Phosphoramidites

MMT-2'-tBDSilyl Adenosine (n-PAC) methyl phosphoramidite

Description: MMT-2'-tBDSilyl Adenosine (n-PAC) methyl phosphoramidite is a reagent used in oligonucleotide synthesis. It comprises adenosine with a monomethoxytrityl (MMT) protecting group at the 2'-position and a tert-butyldimethylsilyl (tBDSilyl) group at the 3'-position. Additionally, the amino group is protected by a phenoxyacetyl (PAC) group. This compound facilitates the controlled synthesis of modified oligonucleotides with enhanced stability and precise chemical modifications.

CAT: BRP-01424

Molecular Formula: C51H65N6O8PSi

Molecular Weight: 949.16

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InChIKey: SRIPSWWUYSURFE-ZPKZLDMBSA-N

CanonicalSMILES: O=C(NC1=NC=NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C=5C=CC=CC5)C6=CC=C(OC)C=C6)C(OP(OC)N(C(C)C)C(C)C)C3O[Si](C)(C)C(C)(C)C)COC=7C=CC=CC7

IUPAC Name: (2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-2-(((4-methoxyphenyl)diphenylmethoxy)methyl)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl methyl diisopropylphosphoramidite

InChI: InChI=1S/C51H65N6O8PSi/c1-35(2)57(36(3)4)66(60-9)64-45-42(31-62-51(37-21-15-12-16-22-37,38-23-17-13-18-24-38)39-27-29-40(59-8)30-28-39)63-49(46(45)65-67(10,11)50(5,6)7)56-34-54-44-47(52-33-53-48(44)56)55-43(58)32-61-41-25-19-14-20-26-41/h12-30,33-36,42,45-46,49H,31-32H2,1-11H3,(H,52,53,55,58)/t42-,45-,46-,49-,66?/m1/s1

Synonyms: 5'-O-MMTr-2'-OTBS A(Pac) OMe-amidite; 5'-O-MMTr-2'-O-TBDMS-A(Pac)-3'-Methoxy-phosphoramidite; Adenosine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5'-O-[(4-methoxyphenyl)diphenylmethyl]-N-(phenoxyacetyl)-, 3'-[methyl bis(1-methylethyl)phosphoramidite]

MMT-2'-tBDSilyl Guanosine (n-PAC) methyl phosphoramidite

Description: MMT-2'-tBDSilyl Guanosine (n-PAC) methyl phosphoramidite is a reagent used in oligonucleotide synthesis. It consists of guanosine with a monomethoxytrityl (MMT) group protecting the 2'-position, a tert-butyldimethylsilyl (tBDSilyl) group protecting the 3'-position, and a phenoxyacetyl (PAC) group protecting the amino group. Additionally, it includes a methyl phosphoramidite moiety. This compound facilitates the controlled synthesis of modified oligonucleotides, providing increased stability and precise chemical modifications.

CAT: BRP-01425

Molecular Formula: C51H65N6O9PSi

Molecular Weight: 965.16

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InChIKey: KJVBHYXASYADQV-YPSZUEOQSA-N

IUPAC Name: (2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-2-(((4-methoxyphenyl)diphenylmethoxy)methyl)-5-(6-oxo-2-(2-phenoxyacetamido)-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl methyl diisopropylphosphoramidite

InChI: InChI=1S/C51H65N6O9PSi/c1-34(2)57(35(3)4)67(61-9)65-44-41(31-63-51(36-21-15-12-16-22-36,37-23-17-13-18-24-37)38-27-29-39(60-8)30-28-38)64-48(45(44)66-68(10,11)50(5,6)7)56-33-52-43-46(56)54-49(55-47(43)59)53-42(58)32-62-40-25-19-14-20-26-40/h12-30,33-35,41,44-45,48H,31-32H2,1-11H3,(H2,53,54,55,58,59)/t41-,44-,45-,48-,67?/m1/s1

Synonyms: 5'-O-MMTr-2'-OTBS G(Pac) OMe-amidite; 5'-O-MMTr-2'-O-TBDMS-G(Pac)-3'-Methoxy-phosphoramidite

2'-tBDSilyl Adenosine (n-PAC) methyl phosphoramidite

Description: 5'-O-DMTr-2'-O-TBDMS-A(Pac)-3'-Methoxy-phosphoramidite is a reagent used in oligonucleotide synthesis. It includes adenosine with a dimethoxytrityl (DMTr) group at the 5'-position, a tert-butyldimethylsilyl (TBDMS) group at the 2'-position, a phenoxyacetyl (Pac) protecting group on the amino group, and a methoxy phosphoramidite at the 3'-position. This configuration enhances stability and allows precise incorporation of adenosine into synthetic oligonucleotides.

CAT: BRP-01426

Molecular Formula: C52H67N6O9PSi

Molecular Weight: 979.18

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InChIKey: PVCNWLDGLBVZQK-KJMRTUCVSA-N

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl methyl diisopropylphosphoramidite

InChI: InChI=1S/C52H67N6O9PSi/c1-35(2)58(36(3)4)68(62-10)66-46-43(31-64-52(37-19-15-13-16-20-37,38-23-27-40(60-8)28-24-38)39-25-29-41(61-9)30-26-39)65-50(47(46)67-69(11,12)51(5,6)7)57-34-55-45-48(53-33-54-49(45)57)56-44(59)32-63-42-21-17-14-18-22-42/h13-30,33-36,43,46-47,50H,31-32H2,1-12H3,(H,53,54,56,59)/t43-,46-,47-,50-,68?/m1/s1

Synonyms: 2'-OTBS A(Pac) OMe-amidite; 5'-O-DMTr-2'-O-TBDMS-A(Pac)-3'-Methoxy-phosphoramidite

2'-tBDSilyl Cytidine (n-PAC) methyl phosphoramidite

Description: 2'-tBDSilyl Cytidine (n-PAC) methyl phosphoramidite is a key reagent used in oligonucleotide synthesis. It consists of cytidine with a tert-butyldimethylsilyl (tBDSilyl) group protecting the 2'-position and a phenoxyacetyl (PAC) group guarding the amino group. Additionally, it contains a methyl phosphoramidite moiety. This compound facilitates the controlled synthesis of modified oligonucleotides, providing enhanced stability and enabling precise chemical modifications.

CAT: BRP-01427

Molecular Formula: C51H67N4O10PSi

Molecular Weight: 955.16

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InChIKey: AJLSWJSVOOCSFR-VUQXMIQESA-N

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2-oxo-4-(2-phenoxyacetamido)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl methyl diisopropylphosphoramidite

InChI: InChI=1S/C51H67N4O10PSi/c1-35(2)55(36(3)4)66(60-10)64-46-43(33-62-51(37-19-15-13-16-20-37,38-23-27-40(58-8)28-24-38)39-25-29-41(59-9)30-26-39)63-48(47(46)65-67(11,12)50(5,6)7)54-32-31-44(53-49(54)57)52-45(56)34-61-42-21-17-14-18-22-42/h13-32,35-36,43,46-48H,33-34H2,1-12H3,(H,52,53,56,57)/t43-,46-,47-,48-,66?/m1/s1

Synonyms: 5'-O-DMTr-2'-OTBS C(Pac) OMe-amidite; 5'-O-DMTr-2'-O-TBDMS-C(Pac)-3'-Methoxy-phosphoramidite

2'-tBDSilyl Guanosine (n-PAC) methyl phosphoramidite

Description: 2'-tBDSilyl Guanosine (n-PAC) methyl phosphoramidite is a reagent commonly used in oligonucleotide synthesis. It consists of guanosine with a tert-butyldimethylsilyl (tBDSilyl) group protecting the 2'-position and a phenoxyacetyl (PAC) group protecting the amino group. Additionally, it features a methyl phosphoramidite moiety. This compound facilitates the controlled synthesis of modified oligonucleotides, providing increased stability and precise chemical modifications.

CAT: BRP-01428

Molecular Formula: C52H67N6O10PSi

Molecular Weight: 995.18

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InChIKey: CEBBQJQCBLOLKE-XIZLBUQOSA-N

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(6-oxo-2-(2-phenoxyacetamido)-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl methyl diisopropylphosphoramidite

InChI: InChI=1S/C52H67N6O10PSi/c1-34(2)58(35(3)4)69(63-10)67-45-42(31-65-52(36-19-15-13-16-20-36,37-23-27-39(61-8)28-24-37)38-25-29-40(62-9)30-26-38)66-49(46(45)68-70(11,12)51(5,6)7)57-33-53-44-47(57)55-50(56-48(44)60)54-43(59)32-64-41-21-17-14-18-22-41/h13-30,33-35,42,45-46,49H,31-32H2,1-12H3,(H2,54,55,56,59,60)/t42-,45-,46-,49-,69?/m1/s1

Synonyms: 5'-O-DMTr-2'-OTBS G(Pac) OMe-amidite; 5'-O-DMTr-2'-O-TBDMS-G(Pac)-3'-Methoxy-phosphoramidite

2'-tBDSilyl Cytidine (n-bz) methyl phosphoramidite

Description: 2'-tBDSilyl Cytidine (n-bz) methyl phosphoramidite is a crucial component in the synthesis of modified oligonucleotides. This compound consists of cytidine with a tert-butyldimethylsilyl (tBDSilyl) group protecting the 2'-position and a benzoyl (n-bz) group guarding the amino group. Additionally, it includes a methyl phosphoramidite moiety. This reagent enables controlled oligonucleotide synthesis, allowing for precise chemical modifications and enhancing the stability of the resulting oligonucleotide strands.

CAT: BRP-01429

CAS: 118684-40-5

Molecular Formula: C50H65N4O9PSi

Molecular Weight: 925.15

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InChIKey: AJJZVDGKUIEJGA-LORUJQNASA-N

CanonicalSMILES: O=C1N=C(C=CN1C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(OP(OC)N(C(C)C)C(C)C)C2O[Si](C)(C)C(C)(C)C)NC(=O)C=6C=CC=CC6

IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl methyl diisopropylphosphoramidite

InChI: InChI=1S/C50H65N4O9PSi/c1-34(2)54(35(3)4)64(59-10)62-44-42(33-60-50(37-21-17-14-18-22-37,38-23-27-40(57-8)28-24-38)39-25-29-41(58-9)30-26-39)61-47(45(44)63-65(11,12)49(5,6)7)53-32-31-43(52-48(53)56)51-46(55)36-19-15-13-16-20-36/h13-32,34-35,42,44-45,47H,33H2,1-12H3,(H,51,52,55,56)/t42-,44-,45-,47-,64?/m1/s1

Synonyms: 5'-O-DMTr-2'-OTBS C(Bz) OMe-amidite; 5'-O-DMTr-2'-O-TBDMS-C(Bz)-3'-Methoxy-phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[methyl bis(1-methylethyl)phosphoramidite]

MMT-2'-tBDSilyl Adenosine (n-bz) methyl phosphoramidite

Description: MMT-2'-tBDSilyl Adenosine (n-bz) methyl phosphoramidite is a reagent utilized in oligonucleotide synthesis. It consists of adenosine with a monomethoxytrityl (MMT) protecting group at the 2'-position and a tert-butyldimethylsilyl (tBDSilyl) group at the 3'-position. The amino group is safeguarded by a benzoyl (bz) group. This compound is employed to synthesize modified oligonucleotides with increased stability and precise chemical modifications.

CAT: BRP-01430

CAS: 101904-21-6

Molecular Formula: C50H63N6O7PSi

Molecular Weight: 919.15

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InChIKey: NUQPPYCKFPVDHB-HHRUMCNBSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OC)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=C(C=C7)OC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-[[di(propan-2-yl)amino]-methoxyphosphanyl]oxy-5-[[(4-methoxyphenyl)-diphenylmethoxy]methyl]oxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C50H63N6O7PSi/c1-34(2)56(35(3)4)64(59-9)62-43-41(31-60-50(37-23-17-13-18-24-37,38-25-19-14-20-26-38)39-27-29-40(58-8)30-28-39)61-48(44(43)63-65(10,11)49(5,6)7)55-33-53-42-45(51-32-52-46(42)55)54-47(57)36-21-15-12-16-22-36/h12-30,32-35,41,43-44,48H,31H2,1-11H3,(H,51,52,54,57)/t41-,43-,44-,48-,64?/m1/s1

Synonyms: Adenosine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5'-O-[(4-methoxyphenyl)diphenylmethyl]-, 3'-[methyl bis(1-methylethyl)phosphoramidite]; 5'-O-MMTr-2'-OTBS A(Bz) OMe-amidite; 5'-O-MMTr-2'-O-TBDMS-A(Bz)-3'-Methoxy-phosphoramidite

MMT-2'-tBDSilyl Guanosine (n-ibu) methyl phosphoramidite

Description: MMT-2'-tBDSilyl Guanosine (n-ibu) methyl phosphoramidite is a reagent commonly used in oligonucleotide synthesis. It consists of guanosine with a monomethoxytrityl (MMT) group protecting the 2'-position, a tert-butyldimethylsilyl (tBDSilyl) group protecting the 3'-position, and an isobutyryl (n-ibu) group protecting the amino group. This compound enables the controlled synthesis of modified oligonucleotides, providing increased stability and precise chemical modifications.

CAT: BRP-01431

Molecular Formula: C47H65N6O8PSi

Molecular Weight: 901.13

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InChIKey: WRCLQRTWWDMGKQ-DMWBDYODSA-N

IUPAC Name: (2R,3R,4R,5R)-4-((tert-butyldimethylsilyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-(((4-methoxyphenyl)diphenylmethoxy)methyl)tetrahydrofuran-3-yl methyl diisopropylphosphoramidite

InChI: InChI=1S/C47H65N6O8PSi/c1-30(2)42(54)50-45-49-41-38(43(55)51-45)48-29-52(41)44-40(61-63(12,13)46(7,8)9)39(60-62(57-11)53(31(3)4)32(5)6)37(59-44)28-58-47(33-20-16-14-17-21-33,34-22-18-15-19-23-34)35-24-26-36(56-10)27-25-35/h14-27,29-32,37,39-40,44H,28H2,1-13H3,(H2,49,50,51,54,55)/t37-,39-,40-,44-,62?/m1/s1

Synonyms: 5'-O-MMTr-2'-OTBS G(iBu) OMe-amidite; 5'-O-MMTr-2'-O-TBDMS-G(iBu)-3'-Methoxy-phosphoramidite

Psoralen 18-Atom Spacer CED phosphoramidite

Description: The Psoralen 18-Atom Spacer CED phosphoramidite is a specialized compound used in nucleic acid synthesis. It combines the photoreactive properties of psoralen with an 18-atom spacer and a CED phosphoramidite group. This enables controlled modification of nucleic acids, allowing for the introduction of psoralen moieties at specific positions within DNA or RNA strands. These modifications can then be crosslinked under ultraviolet (UV) light, making this compound valuable in various molecular biology applications, including DNA-protein interaction studies and nucleic acid structure mapping.

CAT: BRP-01437

Molecular Formula: C36H55N2O11P

Molecular Weight: 722.80

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InChIKey: VDDDZCZDLKUGAG-UHFFFAOYSA-N

CanonicalSMILES: N#CCCOP(OCCOCCOCCOCCOCCOCCOCC1=C(OC2=C1C=C(C(C)=C3)C(OC3=O)=C2C)C)N(C(C)C)C(C)C

IUPAC Name: 2-cyanoethyl (1-(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)-2,5,8,11,14,17-hexaoxanonadecan-19-yl) diisopropylphosphoramidite

InChI: InChI=1S/C36H55N2O11P/c1-26(2)38(27(3)4)50(46-10-8-9-37)47-22-21-44-18-17-42-14-13-40-11-12-41-15-16-43-19-20-45-25-33-30(7)48-36-29(6)35-31(24-32(33)36)28(5)23-34(39)49-35/h23-24,26-27H,8,10-22,25H2,1-7H3

Psoralen phosphoramidite

Description: Psoralen phosphoramidite is a compound used in nucleic acid synthesis, particularly in molecular biology and genetic research. It incorporates a psoralen derivative, a naturally occurring compound known for its ability to crosslink with nucleic acids upon exposure to ultraviolet (UV) light. This phosphoramidite form allows for the controlled addition of psoralen to oligonucleotide chains during solid-phase synthesis, enabling precise positioning within DNA or RNA strands. Psoralen phosphoramidite is valuable for applications involving the study of DNA-protein interactions, nucleic acid structure, and as a tool in various molecular biology techniques.

CAT: BRP-01438

Molecular Formula: C48H55N2O9P

Molecular Weight: 834.93

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InChIKey: BJYRTACQFJUEHM-UHFFFAOYSA-N

CanonicalSMILES: N#CCCOP(OC(COC(C1=CC=CC=C1)(C2=CC=C(OC)C=C2)C3=CC=C(OC)C=C3)COCC4=C(OC5=C4C=C(C(C)=C6)C(OC6=O)=C5C)C)N(C(C)C)C(C)C

IUPAC Name: 1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-((2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)methoxy)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C48H55N2O9P/c1-31(2)50(32(3)4)60(56-25-13-24-49)59-41(28-54-30-44-35(7)57-47-34(6)46-42(27-43(44)47)33(5)26-45(51)58-46)29-55-48(36-14-11-10-12-15-36,37-16-20-39(52-8)21-17-37)38-18-22-40(53-9)23-19-38/h10-12,14-23,26-27,31-32,41H,13,25,28-30H2,1-9H3

Psoralen C-4 CED phosphoramidite

Description: Psoralen C-4 CED phosphoramidite is a specialized compound utilized in nucleic acid synthesis, particularly in molecular biology and genetic research. It likely incorporates a psoralen derivative with modification at the C-4 position, enabling controlled interactions with nucleic acids. The CED phosphoramidite moiety facilitates its incorporation into oligonucleotide chains during solid-phase synthesis, allowing for precise positioning within DNA or RNA strands. This compound is valuable for applications involving psoralen-mediated crosslinking, which is useful for studying DNA-protein interactions and nucleic acid structure.

CAT: BRP-01439

Molecular Formula: C28H39N2O6P

Molecular Weight: 530.59

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InChIKey: KOBCWUDIRGLRAB-UHFFFAOYSA-N

CanonicalSMILES: N#CCCOP(OCCCCOCC1=C(OC2=C1C=C(C(C)=C3)C(OC3=O)=C2C)C)N(C(C)C)C(C)C

IUPAC Name: 2-cyanoethyl (4-((2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)methoxy)butyl) diisopropylphosphoramidite

InChI: InChI=1S/C28H39N2O6P/c1-18(2)30(19(3)4)37(34-14-10-11-29)33-13-9-8-12-32-17-25-22(7)35-28-21(6)27-23(16-24(25)28)20(5)15-26(31)36-27/h15-16,18-19H,8-10,12-14,17H2,1-7H3

Synonyms: Psoralen-C4 CEP; Psoralen C4 Phosphoramidite

2'-O-Methyl-3'-DMT Cytidine (n-bz) 5'-CED phosphoramidite

Description: 2'-O-Methyl-3'-DMT 5-Methyl-Cytidine (N-Bz) 5'-CED Phosphoramidite is a specialized nucleotide compound essential in oligonucleotide synthesis. Featuring a 2'-O-methyl modification and a 3'-DMT protecting group for stability, it also incorporates a 5-methyl-cytidine base with a benzoyl (Bz) modification at the N4 position. Its 5'-CED phosphoramidite functionality enables controlled addition to oligonucleotide chains, offering versatility and precision in molecular biology research and nucleic acid design.

CAT: BRP-01450

CAS: 2101622-72-2

Molecular Formula: C47H54N5O9P

Molecular Weight: 863.93

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InChIKey: MCJDWFDEBMUCDZ-VKBHKTMGSA-N

CanonicalSMILES: N#CCCOP(OCC1OC(N2C=CC(=NC2=O)NC(=O)C=3C=CC=CC3)C(OC)C1OC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C

IUPAC Name: ((2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-methoxytetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C47H54N5O9P/c1-32(2)52(33(3)4)62(58-30-14-28-48)59-31-40-42(43(57-7)45(60-40)51-29-27-41(50-46(51)54)49-44(53)34-15-10-8-11-16-34)61-47(35-17-12-9-13-18-35,36-19-23-38(55-5)24-20-36)37-21-25-39(56-6)26-22-37/h8-13,15-27,29,32-33,40,42-43,45H,14,30-31H2,1-7H3,(H,49,50,53,54)/t40-,42-,43-,45-,62?/m1/s1

Synonyms: Cytidine, N-benzoyl-2'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 2'-O-Me-3'-DMT C(Bz) 5'-CE phosphoramidite; 3'-DMT-2'-OMe-C(Bz)-CE Reverse

2'-O-Methyl-3'-DMT 5-Methyl-Cytidine (n-bz) 5'-CED Phosphoramidite

Description: 2'-O-Methyl-3'-DMT Cytidine (N-Bz) 5'-CED phosphoramidite is a modified nucleotide crucial for precise oligonucleotide synthesis. It incorporates a 2'-O-methyl modification and a 3'-DMT protecting group, ensuring stability during synthesis. Additionally, the cytidine base is modified with a benzoyl (Bz) group, allowing controlled interaction at the N4 position. Its 5'-CED phosphoramidite functionality facilitates stepwise addition to oligonucleotide chains, making it indispensable in molecular biology for tailored nucleic acid design and research applications.

CAT: BRP-01451

Molecular Formula: C48H56N5O9P

Molecular Weight: 877.96

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InChIKey: WSOJMKBDTHLPSQ-AENBYTAOSA-N

IUPAC Name: ((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-methoxytetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C48H56N5O9P/c1-32(2)53(33(3)4)63(59-29-15-28-49)60-31-41-42(43(58-8)46(61-41)52-30-34(5)44(51-47(52)55)50-45(54)35-16-11-9-12-17-35)62-48(36-18-13-10-14-19-36,37-20-24-39(56-6)25-21-37)38-22-26-40(57-7)27-23-38/h9-14,16-27,30,32-33,41-43,46H,15,29,31H2,1-8H3,(H,50,51,54,55)/t41-,42-,43-,46-,63?/m1/s1

Synonyms: 5-Methylcytidine, N-benzoyl-2'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 2'-O-Me-3'-DMT 5-Methyl-C(Bz) 5'-CE phosphoramidite; 3'-DMT-2'-OMe-5-Methyl-C(Bz)-CE Reverse

2'-O-Methyl-3'-DMT 5-Methyl-Uridine 5'-CED Phosphoramidite

Description: 2'-O-Methyl-3'-DMT 5-Methyl-Uridine 5'-CED Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It is characterized by a 2'-O-methyl modification and a 3'-DMT protecting group, ensuring stability during synthesis. Additionally, the uridine base is modified with a methyl group at the 5-position. With its 5'-CED phosphoramidite functionality, this compound facilitates controlled addition to oligonucleotide chains, offering precision and versatility in molecular biology research and nucleic acid design.

CAT: BRP-01452

Molecular Formula: C41H51N4O9P

Molecular Weight: 774.84

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InChIKey: IUNYBTUERIDWLR-VNZAIEIISA-N

IUPAC Name: ((2R,3R,4R,5R)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-methoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C41H51N4O9P/c1-27(2)45(28(3)4)55(51-24-12-23-42)52-26-35-36(37(50-8)39(53-35)44-25-29(5)38(46)43-40(44)47)54-41(30-13-10-9-11-14-30,31-15-19-33(48-6)20-16-31)32-17-21-34(49-7)22-18-32/h9-11,13-22,25,27-28,35-37,39H,12,24,26H2,1-8H3,(H,43,46,47)/t35-,36-,37-,39-,55?/m1/s1

Synonyms: 2'-O-Me-3'-DMT 5-Methyl-U 5'-CE phosphoramidite; 3'-DMT-2'-OMe-5-Methyl-U-CE Reverse

2'-tBDSilyl-3'-DMT-Uridine 5'-CED phosphoramidite

Description: 2'-tBDSilyl-3'-DMT-Uridine 5'-CED phosphoramidite is a specialized nucleotide compound utilized in oligonucleotide synthesis. It is characterized by a 2'-t-butyldimethylsilyl (TBDMS) group protecting the 2' hydroxyl, a 3'-DMT group protecting the 3' hydroxyl, and a uridine base. The 5'-CED phosphoramidite functionality enables controlled addition to oligonucleotide chains during synthesis. This compound provides stability and precise control over nucleotide addition, making it valuable in molecular biology research for designing and synthesizing custom oligonucleotides.

CAT: BRP-01453

CAS: 1146146-30-6

Molecular Formula: C45H61N4O9PSi

Molecular Weight: 861.05

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InChIKey: ADUXPZBKAIWXQM-ZMHKPELYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC1C(C(C(O1)N2C=CC(=O)NC2=O)O[Si](C)(C)C(C)(C)C)OC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: 3-[[(2R,3R,4R,5R)-3-[bis(4-methoxyphenyl)-phenylmethoxy]-4-[tert-butyl(dimethyl)silyl]oxy-5-(2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C45H61N4O9PSi/c1-31(2)49(32(3)4)59(54-29-15-27-46)55-30-38-40(41(58-60(10,11)44(5,6)7)42(56-38)48-28-26-39(50)47-43(48)51)57-45(33-16-13-12-14-17-33,34-18-22-36(52-8)23-19-34)35-20-24-37(53-9)25-21-35/h12-14,16-26,28,31-32,38,40-42H,15,29-30H2,1-11H3,(H,47,50,51)/t38-,40-,41-,42-,59?/m1/s1

Synonyms: Uridine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 2'-O-TBDMS-3'-DMT U 5'-CE phosphoramidite; 3'-DMT-2'-TBDMS-U-CE Reverse

2'-tBDSilyl-3'-DMT-Guanosine (N-iPr PAC) 5'-CED phosphoramidite

Description: 2'-tBDSilyl-3'-DMT-Guanosine (N-iPr PAC) 5'-CED Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It features a 2'-tert-butyldimethylsilyl (tBDSilyl) protecting group and a 3'-dimethoxytrityl (DMT) protecting group for stability during synthesis, with guanosine as the base modified with an isopropyl (N-iPr) phenoxyacetyl (PAC) group. Additionally, it contains a 5'-cyanoethyl (CED) phosphoramidite functionality, enabling controlled addition during synthesis. This compound facilitates stable and precise synthesis of customized oligonucleotides, essential for various molecular biology research applications.

CAT: BRP-01456

CAS: 2095378-87-1

Molecular Formula: C57H74N7O10PSi

Molecular Weight: 1076.30

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InChIKey: MBJRLTFVWCADRZ-WYRUHZNWSA-N

CanonicalSMILES: N#CCCOP(OCC1OC(N2C=NC=3C(=O)N=C(NC(=O)COC4=CC=C(C=C4)C(C)C)NC32)C(O[Si](C)(C)C(C)(C)C)C1OC(C=5C=CC=CC5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)N(C(C)C)C(C)C

IUPAC Name: ((2R,3R,4R,5R)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-((tert-butyldimethylsilyl)oxy)-5-(2-(2-(4-isopropylphenoxy)acetamido)-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C57H74N7O10PSi/c1-37(2)40-20-26-46(27-21-40)69-35-48(65)60-55-61-52-49(53(66)62-55)59-36-63(52)54-51(74-76(12,13)56(7,8)9)50(47(72-54)34-71-75(70-33-17-32-58)64(38(3)4)39(5)6)73-57(41-18-15-14-16-19-41,42-22-28-44(67-10)29-23-42)43-24-30-45(68-11)31-25-43/h14-16,18-31,36-39,47,50-51,54H,17,33-35H2,1-13H3,(H2,60,61,62,65,66)/t47-,50-,51-,54-,75?/m1/s1

Synonyms: 3'-O-DMTr-2'-O-TBDMS-G(iPr-PAC)-5'-CE-Phosphoramidite; 3'-DMT-2'-TBDMS-G(iPr-PAC)-CE Reverse

2'-tBDSilyl-3'-DMT-Adenosine (n-bz) 5'-CED phosphoramidite

Description: 2'-tBDSilyl-3'-DMT-Adenosine (n-bz) 5'-CED phosphoramidite is a specialized nucleotide compound used in oligonucleotide synthesis. It features a 2'-t-butyldimethylsilyl (TBDMS) group protecting the 2' hydroxyl, a 3'-DMT group protecting the 3' hydroxyl, and an adenosine base with a benzoyl (Bz) modification. The 5'-CED phosphoramidite functionality enables controlled addition to oligonucleotide chains during synthesis. This compound offers stability and precise control over nucleotide addition, making it valuable in molecular biology research for custom oligonucleotide design and synthesis.

CAT: BRP-01457

CAS: 1146146-22-6

Molecular Formula: C53H66N7O8PSi

Molecular Weight: 988.19

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InChIKey: LKKBOWOULSPXLM-RFMFGJHUSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)O[Si](C)(C)C(C)(C)C)OC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[tert-butyl(dimethyl)silyl]oxy-5-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]oxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(64-32-18-31-54)65-33-44-46(67-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)47(68-70(10,11)52(5,6)7)51(66-44)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1

Synonyms: ((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite; Adenosine, N-benzoyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 3'-O-DMTr-2'-O-TBDMS-A(Bz)-5'-CE-Phosphoramidite; 3'-DMT-2'-TBDMS-A(Bz)-CE Reverse

2'-tBDSilyl-3'-DMT-Cytidine (n-acetyl) 5'-CED phosphoramidite

Description: 2'-tBDSilyl-3'-DMT-Cytidine (N-acetyl) 5'-CED phosphoramidite is a specialized nucleotide compound utilized in oligonucleotide synthesis. It consists of a 2'-tert-butyldimethylsilyl (tBDSilyl) protecting group and a 3'-dimethoxytrityl (DMT) protecting group for stability during synthesis, with cytidine as the base modified with an acetyl (N-acetyl) group. Additionally, it features a 5'-CED (5'-cyanoethyl) phosphoramidite functionality, allowing controlled addition during synthesis. This compound enables precise and stable synthesis of custom oligonucleotides, essential for various molecular biology research applications.

CAT: BRP-01459

CAS: 1146146-25-9

Molecular Formula: C47H64N5O9PSi

Molecular Weight: 902.10

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InChIKey: GNFNITVIZVVSKA-YOEDQOPESA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC1C(C(C(O1)N2C=CC(=NC2=O)NC(=O)C)O[Si](C)(C)C(C)(C)C)OC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: N-[1-[(2R,3R,4R,5R)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[tert-butyl(dimethyl)silyl]oxy-5-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]oxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C47H64N5O9PSi/c1-32(2)52(33(3)4)62(57-30-16-28-48)58-31-40-42(43(61-63(11,12)46(6,7)8)44(59-40)51-29-27-41(49-34(5)53)50-45(51)54)60-47(35-17-14-13-15-18-35,36-19-23-38(55-9)24-20-36)37-21-25-39(56-10)26-22-37/h13-15,17-27,29,32-33,40,42-44H,16,30-31H2,1-12H3,(H,49,50,53,54)/t40-,42-,43-,44-,62?/m1/s1

Synonyms: 3'-O-DMTr-2'-O-TBDMS-C(Ac)-5'-CE-Phosphoramidite; 3'-DMT-2'-TBDMS-C(Ac)-CE Reverse; Cytidine, N-acetyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

DMT-butane-Diol phosphoramidite

Description: DMT-butane-Diol phosphoramidite is a compound utilized in oligonucleotide synthesis and phosphoramidite chemistry. It acts as a phosphitylating reagent for introducing nucleotide phosphoramidites onto solid supports during the synthesis of oligonucleotides. This compound features a butyl chain with a bis(4-methoxyphenyl)(phenyl)methoxy group attached, along with a 2-cyanoethyl group and diisopropylamidophosphite functionality. Its role in oligonucleotide synthesis involves controlled addition to the growing oligonucleotide chain, enabling precise sequence design and customization for various molecular biology applications.

CAT: BRP-01464

CAS: 225786-84-5

Molecular Formula: C34H45N2O5P

Molecular Weight: 592.71

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InChIKey: IEDMPIUZZYENNJ-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)OCCC#N

IUPAC Name: 3-[4-[bis(4-methoxyphenyl)-phenylmethoxy]butoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C34H45N2O5P/c1-27(2)36(28(3)4)42(41-26-12-23-35)40-25-11-10-24-39-34(29-13-8-7-9-14-29,30-15-19-32(37-5)20-16-30)31-17-21-33(38-6)22-18-31/h7-9,13-22,27-28H,10-12,24-26H2,1-6H3

Synonyms: 4-[Bis(4-methoxyphenyl)(phenyl)methoxy]butyl 2-cyanoethyl diisopropylamidophosphite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 4-[bis(4-methoxyphenyl)phenylmethoxy]butyl 2-cyanoethyl ester; 4-[Bis(4-methoxyphenyl)phenylmethoxy]butyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 4-[bis(4-methoxyphenyl)phenylmethoxy]butyl 2-cyanoethyl ester

Polyethyleneglycol 4500 CED phosphoramidite

Description: Polyethyleneglycol 4500 CED phosphoramidite is a specialized compound utilized in oligonucleotide synthesis. It consists of a polyethylene glycol (PEG) chain with a molecular weight of 4500 Da, modified with a 5'-cyanoethyl (CED) phosphoramidite functionality. This compound serves as a linker or spacer molecule, aiding in the conjugation or attachment of oligonucleotides to various biomolecules or surfaces. The PEG chain offers flexibility and water solubility, while the CED phosphoramidite allows controlled addition during synthesis, facilitating the synthesis of PEGylated oligonucleotides for various biomedical and biotechnological applications, such as drug delivery systems or diagnostics.

CAT: BRP-01465

Molecular Weight: 4500.52

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MMT-2'-tBDSilyl Adenosine (n-PAC) methyl phosphoramidite

MMT-2'-tBDSilyl Guanosine (n-PAC) methyl phosphoramidite

2'-tBDSilyl Adenosine (n-PAC) methyl phosphoramidite

2'-tBDSilyl Cytidine (n-PAC) methyl phosphoramidite

2'-tBDSilyl Guanosine (n-PAC) methyl phosphoramidite

2'-tBDSilyl Cytidine (n-bz) methyl phosphoramidite

MMT-2'-tBDSilyl Adenosine (n-bz) methyl phosphoramidite

MMT-2'-tBDSilyl Guanosine (n-ibu) methyl phosphoramidite

Psoralen 18-Atom Spacer CED phosphoramidite

Psoralen phosphoramidite

Psoralen C-4 CED phosphoramidite

2'-O-Methyl-3'-DMT Cytidine (n-bz) 5'-CED phosphoramidite

2'-O-Methyl-3'-DMT 5-Methyl-Cytidine (n-bz) 5'-CED Phosphoramidite

2'-O-Methyl-3'-DMT 5-Methyl-Uridine 5'-CED Phosphoramidite

2'-tBDSilyl-3'-DMT-Uridine 5'-CED phosphoramidite

2'-tBDSilyl-3'-DMT-Guanosine (N-iPr PAC) 5'-CED phosphoramidite

2'-tBDSilyl-3'-DMT-Adenosine (n-bz) 5'-CED phosphoramidite

2'-tBDSilyl-3'-DMT-Cytidine (n-acetyl) 5'-CED phosphoramidite

DMT-butane-Diol phosphoramidite

Polyethyleneglycol 4500 CED phosphoramidite

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