siRNA libraries had brought about a revolution in the efficiency of functional genomics research, which had realized a high-throughput, low-cost, and ultra-fast way of gene function research and screening. Moreover, siRNA libraries provide a novel and efficient way for gene function screening, disease mechanism research, target discovery and drug development. During recent years, the development of siRNA libraries has advanced many original and breakthrough scientific research results, especially in discovering brand-new targets coupled with the high content analysis and screening platform, making the application of siRNA libraries more extensive.
BOC RNA provides comprehensive predesigned siRNA libraries to meet the research needs in the biology and drug discovery fields.
BOC RNA uses a unique siRNA design algorithm to screen efficient siRNA target sites with an excellent success rate. We fully consider important parameters including base composition, the number of consecutive bases, thermodynamic instability, energy distribution, and base preference. Through BLAST search, we can remove sequences that span important regions similar to off-target transcripts, polymorphic regions (such as SNPs), or siRNA predicted to cause antiviral responses to minimize off-target effects.
BOC RNA’s predesigned siRNA library provides the most attractive siRNA collection for high-throughput screening by targeting genes with high therapeutic value. Flexible product format helps study specific gene combinations or life scientists who need to target all available drug genomes. Through the real-time PCR analysis on hundreds of predesigned siRNAs, 80% of siRNA knockdown efficiency is >75%, and more than 40% of siRNA induces target silencing >90%.
| Catalog | Product Name | Inquiry |
| BRJ-001 | Human Apoptosis siRNA Library | Inquiry |
| BRJ-002 | Human Cancer Genome siRNA Library | Inquiry |
| BRJ-003 | Human Cell Cycle Regulation siRNA Library | Inquiry |
| BRJ-004 | Human Cell Surface siRNA Library | Inquiry |
| BRJ-005 | Human DNA Damage Response siRNA Library | Inquiry |
| BRJ-006 | Human Drug Targets siRNA Library (384well) | Inquiry |
| BRJ-007 | Human Drug Targets siRNA Library (96well) | Inquiry |
| BRJ-008 | Human Drug Transporter siRNA Library | Inquiry |
| BRJ-009 | Human Druggable Genome siRNA Library (384well) | Inquiry |
| BRJ-010 | Human Druggable Genome siRNA Library (96well) | Inquiry |
| BRJ-011 | Human Epigenetics siRNA Library | Inquiry |
| BRJ-012 | Human Genome siRNA Library | Inquiry |
| BRJ-013 | Human GPCR siRNA Library | Inquiry |
| BRJ-014 | Human Ion Channel siRNA Library | Inquiry |
| BRJ-015 | Human Kinase siRNA Library | Inquiry |
| BRJ-016 | Human Membrane Trafficking siRNA Library | Inquiry |
| BRJ-017 | Human Nuclear Hormone Receptor siRNA Library | Inquiry |
| BRJ-018 | Human Phosphatase siRNA Library | Inquiry |
| BRJ-019 | Human Protease siRNA Library | Inquiry |
| BRJ-020 | Human Transcription Factor siRNA Library | Inquiry |
| BRJ-021 | Human Tumor Suppressor siRNA Library | Inquiry |
| BRJ-022 | Human Ubiquitin siRNA Library | Inquiry |
If you need a siRNA list or other information that is not reflected in these predefined collections, or want to discuss your research with our technical experts, please contact us.
We offer comprehensive libraries targeting specific pathways including apoptosis, kinase, epigenetics, and whole-genome collections, with each gene targeted by multiple optimized siRNA sequences.
Our proprietary algorithm evaluates base composition, thermodynamic properties, and off-target potential through BLAST analysis, while chemical modifications further enhance specificity and stability.
Libraries are provided in multi-well plates with individual gene targeting, available in both pre-mixed formats and single-siRNA configurations for flexible experimental setups.
Extensive testing demonstrates >75% knockdown efficiency for 80% of siRNAs, with over 40% achieving >90% target silencing, validated through real-time PCR analysis.
Yes, we provide fully customizable library services, allowing researchers to target specific gene combinations or create hybrid libraries tailored to unique experimental requirements.
Our collections primarily focus on human genomes, with additional options available for other model organisms to support comparative genomic studies.
