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Custom Fluorescence-labeled siRNA

What is Fluorescence-labeled siRNA?

Fluorescence-labeled siRNA can be monitored by fluorescence microscopy (for example: confocal) or flow cytometry, so it can be used to verify the transfection efficiency, optimize the transfection conditions, research of intracellular distribution and double labeling. 

Custom Fluorescence-labeled siRNA Services

BOC RNA provides high-quality and cost-effective siRNA with various fluorescence labels and flexible synthesis scales to meet customers' needs.

All our fluorescence-labeled siRNAs are purified by HPLC, and supplied in lyophilized powder. The quantity we can provide ranges from 2 OD to 250 OD.

Catalog No.LabellingQuantityPurificationPriceLead Time
BRE-0015' 6-FAM2 OD-250 ODHPLCInquiryInquiry
BRE-0023' 6-FAM2 OD-250 ODHPLCInquiryInquiry
BRE-0035' TET2 OD-250 ODHPLCInquiryInquiry
BRE-0043' TET2 OD-250 ODHPLCInquiryInquiry
BRE-0055' HEX2 OD-250 ODHPLCInquiryInquiry
BRE-0063' HEX2 OD-250 ODHPLCInquiryInquiry
BRE-0075' TAMRA2 OD-250 ODHPLCInquiryInquiry
BRE-0083' TAMRA2 OD-250 ODHPLCInquiryInquiry
BRE-0095' ROX2 OD-250 ODHPLCInquiryInquiry
BRE-0103' ROX2 OD-250 ODHPLCInquiryInquiry
BRE-0115' CY32 OD-250 ODHPLCInquiryInquiry
BRE-0123' CY32 OD-250 ODHPLCInquiryInquiry
BRE-0135' CY52 OD-250 ODHPLCInquiryInquiry
BRE-0143' CY52 OD-250 ODHPLCInquiryInquiry
BRE-0155' CY5.52 OD-250 ODHPLCInquiryInquiry
BRE-0163' CY5.52 OD-250 ODHPLCInquiryInquiry
BRE-0175' CY72 OD-250 ODHPLCInquiryInquiry
BRE-0183' CY72 OD-250 ODHPLCInquiryInquiry
BRE-0195' Dyomics6812 OD-250 ODHPLCInquiryInquiry
BRE-0203' Dyomics6812 OD-250 ODHPLCInquiryInquiry
BRE-0215' Dyomics7812 OD-250 ODHPLCInquiryInquiry
BRE-0223' Dyomics7812 OD-250 ODHPLCInquiryInquiry
BRE-0235' Texas Red2 OD-250 ODHPLCInquiryInquiry
BRE-0243' Texas Red2 OD-250 ODHPLCInquiryInquiry
BRE-0255' Methlyene Blue2 OD-250 ODHPLCInquiryInquiry
BRE-0263' Methlyene Blue2 OD-250 ODHPLCInquiryInquiry
BRE-0275' JOE2 OD-250 ODHPLCInquiryInquiry
BRE-0283' JOE2 OD-250 ODHPLCInquiryInquiry
BRE-0295' AMCA2 OD-250 ODHPLCInquiryInquiry
BRE-0303' AMCA2 OD-250 ODHPLCInquiryInquiry
BRE-0315' Dabcyl2 OD-250 ODHPLCInquiryInquiry
BRE-0323' Dabcyl2 OD-250 ODHPLCInquiryInquiry
BRE-0335' BHQ-12 OD-250 ODHPLCInquiryInquiry
BRE-0343' BHQ-12 OD-250 ODHPLCInquiryInquiry
BRE-0355' BHQ-22 OD-250 ODHPLCInquiryInquiry
BRE-0363' BHQ-22 OD-250 ODHPLCInquiryInquiry
BRE-0375' other fluorescent dye2 OD-250 ODHPLCInquiryInquiry
BRE-0383' other fluorescent dye2 OD-250 ODHPLCInquiryInquiry

Please send email to if you need other labeling.

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Frequently Asked Questions (FAQ)

What are the main applications of fluorescence-labeled siRNA?

Fluorescence-labeled siRNA enables real-time tracking of transfection efficiency, optimization of delivery conditions, intracellular distribution studies, and multi-labeling experiments using microscopy and flow cytometry.

What fluorescent dyes are available for siRNA labeling?

We offer comprehensive dye options including FAM, Cy3, Cy5, Alexa Fluor series, and other fluorophores to match various detection systems and experimental requirements.

How does fluorescence labeling affect siRNA functionality?

Our optimized labeling strategies maintain siRNA silencing activity while providing strong fluorescence signals, with validation data confirming minimal impact on gene knockdown efficiency.

Can multiple fluorophores be incorporated on a single siRNA?

Yes, we provide dual-labeling services with compatible dye combinations for advanced applications such as FRET studies and multi-channel detection experiments.

What purification standards ensure labeled siRNA quality?

All fluorescence-labeled siRNAs undergo rigorous HPLC purification, mass spectrometry verification, and functional validation to guarantee optimal performance in both imaging and gene silencing applications.

What scale options are available for fluorescent siRNA synthesis?

We offer flexible synthesis scales from research quantities (2 OD) to bulk production (250 OD), with customization options for specialized labeling requirements.

Complementary siRNA Modification Services

* Only for research. Not suitable for any diagnostic or therapeutic use.
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