The control experiment is very important to get correct data in the experiment.
BOC RNA provides both positive and negative siRNA control. Our controls can be used to optimize the RNAi experimental condition. Transfection efficiency can be observed easily by fluorescence-labeled negative control. The effect of gene silencing can be identified by qPCR or Western Blot.
siRNA positive control is the known siRNA which can silence specific gene, it can be used in control experiment to ensure the effect of gene silencing.
BOC RNA provides high-quality and effective siRNA positive and negative for the customers' control experiment.
All of our siRNA controls are purified by HPLC, and supplied in lyophilized powder. The quantity of our siRNA controls is usually 1 OD.
| Catalog No. | Product | Quantity | Purification | Price | Times |
| BRF-001 | Positive control siRNA | 1 OD | HPLC | Inquiry | Inquiry |
| BRF-002 | Negative control siRNA | 1 OD | HPLC | Inquiry | Inquiry |
| BRF-003 | Fluorescence-labeled negative control siRNA | 1 OD | HPLC | Inquiry | Inquiry |
Please send email to if you need other quantities or other positive/negative control siRNA.
siRNA controls are essential for optimizing transfection conditions, validating experimental systems, assessing silencing efficiency, and ensuring data reliability in RNAi experiments.
Our negative controls are carefully designed with no homology to known genes, undergo comprehensive BLAST analysis, and maintain physical properties similar to active siRNAs while ensuring biological inertness.
All positive controls are experimentally validated for >80% knockdown efficiency, with performance data available for reference genes across common cell lines and experimental conditions.
We offer multiple fluorescent options including Cy3, Cy5, and FAM labels, optimized for detection by fluorescence microscopy, confocal imaging, and flow cytometry applications.
Controls are provided as lyophilized powders and should be stored at -20°C, reconstituted in RNase-free buffer, and aliquoted to maintain stability and prevent degradation.
Yes, we provide custom control design services for unique experimental requirements, including species-specific sequences and specialized validation protocols.
