Custom Oligo Synthesis

Custom Oligo Synthesis

BOC RNA provides high purity customized oligonucleotide production services with a variety of chemistry modifications, specifications, which can be constructed according to your application to meet the research needs in biology, diagnostics, and drug discovery.

Customized oligonucleotide synthesis service includes, but not limited to:

  • cGMP and research-grade oligonucleotide synthesis
  • High-throughput DNA and RNA oligonucleotide synthesis
  • Standard and customized long oligonucleotide synthesis
  • Oligonucleotide modification of various oligonucleotide synthesis scales
  • Extensive purification, specifications, and packaging
  • Mass spectrometry quality control

Our ability

  • Oligonucleotides customization
  • BOC RNA uses phosphoramidite solid-phase synthesis to synthesize unmodified or modified oligonucleotides with specific sequences and provides large-scale customized unmodified oligonucleotide synthesis. These DNA or RNA oligonucleotides synthesized by solid-phase phosphoramidite chemistry can be used in various molecular biology applications, such as PCR, real-time PCR (RT-PCR), sequencing, site-directed mutagenesis, single nucleotide polymorphism (SNP) analysis, microarray, and various therapeutic applications.

  • Purification
  • Each oligonucleotide is strictly monitored during the synthesis process and controlled under BOC RNA's strict quality assurance and quality control standards. The final product is identified by mass spectrometry, and its purity is analyzed by high-throughput electrophoresis or HPLC according to purification options to achieve the required purity.

  • Modifications/labeling

    BOC RNA provides comprehensive modifications for your research needs, including

    • General modifications, such as modified bases, phosphorylation, thiolation, bonding, etc.
    • Labels, such as fluorescent/non-fluorescent dye labels, dual-labeled probes, and multiple RT-PCR labels.
    • Backbone modifications, such as DNA containing phosphorothioate bonds.

    For more details, please refer to our oligo modifications service.

  • Available scales
  • Flexible Synthesis Scales: 20 nmol, 50 nmol, 200 nmol, 1μmol, 5μmol and 10μmol. Bulk orders are available upon request.

Workflow of custom oligo synthesis service

Custom Oligo Synthesis

Competitive advantages

  • Comprehensive modification and labeling
  • From conventional modification to fluorescent/non-fluorescent labeling, even double and multiple labeling

  • Flexible composition ratio
  • Experienced team
  • Scientists and employees with more than 15 years of experience in oligonucleotide synthesis and modification

  • High-quality
  • Comprehensive quality control report

  • Competitive price
  • Fast delivery

If you have any questions, please feel free to contact us.

* Only for research. Not suitable for any diagnostic or therapeutic use.
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