GMP Oligos - RNA / BOC Sciences

Services Details

For more than 15 years, BOC Sciences has been manufacturing oligonucleotides for pre-clinical, clinical, pharmaceutical, food safety, and animal health industries.

BOC Sciences' Manufacturing Capability

BOC Sciences has manufacturing facilities with GMP and ISO certifications. We can provide customized and flexible oligonucleotide GMP production services to meet different GMP-grade production needs. We exceed our customers' expectations by providing exceptional personalized solutions through reproducible systems that meet regulatory standards.

ISO 13485:2003 & ISO 9001:2008 certified	Enables us to design, develop (R&D) and produce oligonucleotide-related products for life science research
Total Product Quality Support	All products are produced in special cleanroom equipment with guaranteed stability. Potential contamination is eliminated. Each oligonucleotide has undergone strict QC and HPLC purification.
Logical, Creative Solutions	We provide a full set of personalized services from research to commercialization. Multiple clean rooms provide maximum flexibility for continuous and parallel production of cGMP-grade oligonucleotides.
Customer-Centric Customization	Provide flexible, customer-defined ordering methods to meet each requirement. Each order is managed by a dedicated cGMP project manager

BOC Sciences' GMP Oligo Manufacturing

GMP Oligonucleotide Manufacturing

Process development
Scale-up, scale-down & process transfer
Proficient in a wide range of oligonucleotide synthesis solutions such as solid phase synthesis.
Production capacity ranges from milligrams to hundreds of kilograms
State-of-the-art technology in oligonucleotide synthesis and downstream processing
Quality-controlled cGMP oligonucleotide laboratory
Purification and verification

BOC Sciences' Oligo Synthesis Service

Types of Oligonucleotides	Oligonucleotide Conjugates	Oligonucleotide Modifications
DNA Oligonucleotide RNA Oligonucleotide Antisense Oligonucleotide(ASO) siRNA mRNA CpG Oligonucleotide SgRNA (for CRISPR/Cas9) Aptamer Catalytically Active Oligonucleotide …	Antibody Oligonucleotide Conjugates Peptide Oligonucleotide Conjugates GalNAc Oligonucleotide Conjugates Protein Oligonucleotide Conjugates Lipids Oligonucleotide Conjugates Enzyme Oligonucleotide Conjugates Nanoparticle Oligonucleotide Conjugates CPP-Oligonucleotide Conjugates Polymer-Oligonucleotide Conjugation …	Oligo Fluorescent Labeling Oligo Backbone Modification Oligo Base Modification Oligo Splicing And Chemical Modification Oligo Spacer Modification Oligo Phosphorylation Modification …

Oligonucleotide Applications

Gene Therapy: Oligonucleotides are mainly involved in the process of RNA interference (RNAi) to achieve specific inhibition of the expression of target genes. Both small interfering RNA (siRNA) and microRNA (miRNA) are common RNAi tools.

Genomics Research: Oligonucleotides can be used in DNA sequencing technologies to accelerate in-depth development of the structure and function of genomes.

Gene Editing: Oligonucleotides play an important role in CRISPR/Cas9 gene editing by helping sgCas9 proteins to make specific gene modifications on target DNA via sgRNA.

Diagnostic Tool: Oligonucleotides can be used as molecular probes to detect specific genes or viral sequences, thus playing a role in medical diagnostics and disease monitoring.

Oligonucleotide Drug Development: The specific properties of oligonucleotide molecules can be used to intervene in disease onset and progression, usually by targeting disease-associated regulation of gene expression, protein function, or viral replication. Oligonucleotide drugs can be developed for the treatment of cancer, hereditary diseases, cardiovascular diseases, neurodegenerative diseases etc.

Advantages of Our GMP Oligos Services

High quality and Compliant Oligonucleotides: As GMP requires strict quality control and management, BOC Sciences ensures the delivery of high quality, pure and GMP compliant oligonucleotide products.
Experienced Team: BOC Sciences has a team of experienced and professional experts who are able to rationally plan the production process, maintain quality control throughout the process, and respond to potential problems in a timely manner.
A Trusted and Well-known Contract Manufacturing Partner: GMP certification is a strong competitive advantage in the marketplace for BOC Sciences' oligonucleotide products to gain customers' trust.
State of the Art Manufacturing Facilities: BOC Sciences has leading-edge production equipment, as well as a well-established system of environmental management and facility maintenance to ensure that the production environment is up to standard, thus guaranteeing the high purity of the oligonucleotide products.

For more detail about our GMP oligos manufacturing services, please feel free to contact us.

* Only for research. Not suitable for any diagnostic or therapeutic use.

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Highlighted Services

GMP Oligonucleotide Manufacturing Service

For more than 15 years, BOC Sciences has been manufacturing oligonucleotides for pre-clinical, pharmaceutical, food safety, and animal health industries. We provide customized and flexible oligonucleotide GMP or non-GMP production services to meet different production needs.

Lipid Nanoparticle(LNP) for RNA Delivery

BOC Sciences offers comprehensive LNP- mRNA delivery services tailored to meet the specific needs of mRNA vaccine development. Our expertise in nanoparticle formulation and mRNA chemistry enables us to design custom LNP formulations optimized for stability, efficacy, and safety.

GalNAc-siRNA Conjugates

BOC Sciences promises to offer you with GalNAc-siRNA conjugation services to help you conduct further research on GalNAc-siRNA conjugates and explore their mores omnics capabilities, the working mechanism as well as their potential therapeutic profiles.

Custom Aptamer Synthesis

BOC Sciences offers aptamer customization services to generate high-quality aptamers tailored to your goals, delivering excellent results even for the most difficult target molecules.

Peptide-Oligonucleotide Conjugation

BOC Sciences is committed to providing our customers with comprehensive modification and labeling, offering affordable custom oligonucleotides or peptide-oligonucleotide conjugates.