GMP Oligonucleotide Manufacturing Services

GMP Oligonucleotide Manufacturing Services

For more than 15 years, BOC Sciences has been manufacturing oligonucleotides for pre-clinical, clinical, pharmaceutical, food safety, and animal health industries.

BOC Sciences has manufacturing facilities with GMP and ISO certifications. We can provide customized and flexible oligonucleotide GMP production services to meet different GMP-grade production needs. We exceed our customers’ expectations by providing exceptional personalized solutions through reproducible systems that meet regulatory standards.

Our Capabilities

ISO 13485:2003 & ISO 9001:2008 certified
  • Enables us to design, develop (R&D) and produce oligonucleotide-related products for life science research
Total Product Quality Support
  • All products are produced in special cleanroom equipment with guaranteed stability.
  • Potential contamination is eliminated.
  • Each oligonucleotide has undergone strict QC and HPLC purification.
Logical, Creative Solutions
  • We provide a full set of personalized services from research to commercialization.
  • Multiple clean rooms provide maximum flexibility for continuous and parallel production of cGMP-grade oligonucleotides.
Customer-Centric Customization
  • Provide flexible, customer-defined ordering methods to meet each requirement.
  • Each order is managed by a dedicated cGMP project manager

Our services for your GMP-level oligonucleotide project include:

  • Process development
  • Scale-up, scale-down & process transfer
  • Production capacity ranges from milligrams to hundreds of kilograms
  • State-of-the-art technology in oligonucleotide synthesis and downstream processing
  • Quality-controlled cGMP oligonucleotide laboratory
  • Purification and verification

We provide the following oligonucleotide categories and conjugates/modifications:

Oligonucleotide categoriesOligonucleotide conjugates/modifications
  • DNA/RNA oligonucleotide
  • Antisense oligonucleotide (ASO)
  • siRNA
  • mRNA
  • CpG oligonucleotide
  • SgRNA for CRISPR/Cas9 technology
  • Aptamers
  • Catalytically active oligonucleotide
  • GalNAc
  • PEG
  • Cholesterol
  • Peptides
  • Lipids
  • Various base and sugar modifications
  • Various backbone modifications
  • Various labeling and fluorescent modifications


  • Oligonucleotide drug development
  • Health care -IVD diagnosis
  • Contract organization -custom analysis reagents
  • Commercial IVD company -standard PCR
  • Consumer products -sequencing
  • Medical genetics testing - next-generation sequencing
  • Forensics -microarray


  • High-quality, reliable, responsive, and flexible
  • Experienced production facilities
  • A trusted and well-known contract manufacturing partner

For more detail about our GMP-grade oligonucleotides manufacturing, please contact us.

* Only for research. Not suitable for any diagnostic or therapeutic use.
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