Diagnostic Probes & Oligos

BOC Sciences, with our expertise, offers a wide range of high-quality diagnostic probes that meet the needs of research and industry from R&D to production. We also provide a variety of modifications or markers on the 5' and 3' ends of probes, or specified locations according to the specific needs of customers.

Diagnostic Probes & Oligos: An Introduction

• What is Molecular diagnostic

Molecular diagnostic technology refers to the uses of DNA or RNA as template materials, and applies with molecular biology techniques to diagnose human body state and diseases by detecting defective or abnormal genes expression. The basic principle of molecular diagnostic is to determine the structure, amount, and expression changes in DNA or RNA, thus further verifying gene stability and abnormality. The molecular diagnostic technique is important for the prognosis, diagnosis and treatment of diseases. According to layman's terms, all methodological techniques based on molecular biology are so-called molecular diagnostic techniques, such as PCR technology, gene sequencing technology, etc. With the rapid development of molecular diagnostic technology, customers have gained more advanced requirements for diagnostic probe products.

• What are Diagnostic Probes?

Diagnostic probes are synthetic DNA or RNA molecules that are designed to hybridize (bind) to specific sequences of nucleic acids. They are usually labeled with a fluorescent, radioactive or other detectable marker that makes them useful in identifying and quantifying nucleic acids in various samples.

• Uses of Diagnostic Probes

Diagnostic probes have several uses in biological research and medicine. They are commonly used to identify pathogens in clinical specimens, such as viruses or bacteria, which may cause diseases. They are also utilized in forensic science to identify individuals through DNA analysis.

In addition, these molecules are useful in gene expression analysis and in detecting genetic mutations that may lead to the development of diseases such as cancer. Diagnostic probes and oligos are therefore essential tools in developing personalized medicine and screening for genetic predisposition to diseases.

BOC Sciences' Diagnostic Probes and Oligos

Benefits of BOC Sciences' Diagnostic Probes

1. High purity and low background noise probes are made with fine purification technology.
2. Stringent quality control system ensures real-time monitoring of probe production and batch-to-batch consistency.
3. Highly customizable: offers a wide range of synthetic specifications from nmol to umol, HPLC, PAGE, and other high-purity, high-standard purification methods.
4. Optional custom QC assays:
1. Fluorescence value enzyme cut increment (FLU): ensure that the fluorescence and quenching groups of TaqMan probes, molecular beacons and other conventional double-labeled primers function properly.
2. Positive template control assay (PTC): ensures the amplification efficiency of positive targets.
3. Human source contamination detection (HSC): avoid primer contamination of human gDNA.
4. No template control assay (NTC): eliminate false positives for negative controls.
5. Cyclical quality tracking system and issue regular quality tracking reports establishment.

Remark

1. The guarantee effects limit to human-derived mouse sources. Other species have no guaranteed effectiveness. The clarity is related to the sample's quality, RNA abundance, slice, and photographing equipment, so clarity effect is not guaranteed.
2. The above invalidity needs to be confirmed by the company. If verification meets the company's shipping standards, customers are responsible for relevant fees.
3. For all affirmation or validity confirmation, different cells pertain to different expressions and rules, so only one type of cell or sample is needed to confirm the effect. There is no guarantee that all cells or samples will achieve a positive result.

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Diagnostic Probes & Oligos

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