Chain Terminators

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Modified DNA or RNA oligonucleotides contribute to the understanding of the mechanistic and stereochemical aspects of many biochemical reactions and processes. BOC RNA offers a full range of high quality custom DNA/RNA oligonucleotide modification services through direct solid-phase chemical synthesis or enzyme-assisted methods.

What is RNA Chain Termination?

Chain termination refers to the process in which chain carriers die out and do not regenerate in a chain reaction, resulting in the termination of chain propagation. Natural breakage of the active chain is unavoidable in controlled growth reactions, which include chain transfer and chain termination reactions. There is an essential difference between the two:

What is RNA Terminator?

Terminator is also known as polymerization stabilizer, chain terminator or retarder. It is the agent used in polymerization process of polymer chemical chain, which can terminate the continuing polymerization reaction. These substances can react with initiating and growing radicals, rendering them inactive, thus terminating chain growth and halting polymerization. High-quality polymer products with uniform molecular weight and stable molecular structure can be obtained by terminating polymerization in due course.

Terminators can be divided into two categories:

The following factors should be considered when selecting a terminator:

We Provide the Following Chain Terminators

Chain TerminatorsShort CodePrice
3' Inverted abasicbInquiry
3' Inverted deoxy-thymidineidT-3'Inquiry
3'-Terminal 3'-Deoxy-Guanosine3'dGInquiry
3'-Terminal dideoxy-cytidineddCInquiry
5' Inverted deoxy-thymidineidTInquiry
5' Terminal 5'-deoxy-ribo-adenosine5'dAInquiry
5' Terminal 5'-deoxy-ribo-cytidine5'dCInquiry
5' Terminal 5'-deoxy-ribo-guanosine5'dGInquiry
5' Terminal 5'-deoxy-ribo-uridine5'dUInquiry

Application of RNA Chain Terminators

Advantages of RNA Chain Terminators from BOC Sciences

* Only for research. Not suitable for any diagnostic or therapeutic use.
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