Phosphoramidites

2'-OMe-dmf-G-CE Phosphoramidite

Description: 2'-OMe-dmf-G-CE Phosphoramidite, a vital compound in the biomedicine industry, is leveraged for the crucial synthesis of oligonucleotides. These tiny yet potent molecules are widely utilized in treating an array of afflictions such as cancer, viral infections, and genetic disorders. Devised to heighten the steadfastness and efficacy of oligonucleotides, our product offers patients the potential for better therapeutic outcomes.

CAT: BRP-00014

CAS: 128219-77-2

Molecular Formula: C44H55N8O8P

Molecular Weight: 854.92

Purity: ≥95%

Appearance: white powder

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InChIKey: ZGDBCILCTOHNAB-NANSYJOBSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OC)N2C=NC3=C2N=C(NC3=O)N=CN(C)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

IUPAC Name: N'-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide

InChI: InChI=1S/C44H55N8O8P/c1-29(2)52(30(3)4)61(58-25-13-24-45)60-38-36(59-42(39(38)56-9)51-28-46-37-40(51)48-43(49-41(37)53)47-27-50(5)6)26-57-44(31-14-11-10-12-15-31,32-16-20-34(54-7)21-17-32)33-18-22-35(55-8)23-19-33/h10-12,14-23,27-30,36,38-39,42H,13,25-26H2,1-9H3,(H,48,49,53)/b47-27+/t36-,38-,39-,42-,61?/m1/s1

Synonyms: 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-methylguanosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; DMT-2'-O-Me-G(dmf)-CE Phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 2'-OMe-G-CE Phosphoramidite; 2'-O-Methyl Guanosine (n,n-dmf) CED phosphoramidite

5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite

Description: 5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite stands as an indispensable entity within the realm of biomedicine, wherein its applications for the synthesis of nucleic acids in investigative capacities hold paramount significance. DNA and RNA oligonucleotides rely on this product as their cornerstone, as it seamlessly integrates 2'-deoxyuridine into nucleic acid sequences with exacting efficiency. Aiding the progression of pharmaceutical innovation, gene therapy, and genetic exploration, it emerges as an invaluable instrument that propels advancements in the remediation of diverse medical afflictions.

CAT: BRP-00117

CAS: 109389-30-2

Molecular Formula: C39H47N4O8P

Molecular Weight: 730.80

Purity: ≥95%

Appearance: White to off-white powder

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10 g	$439	In stock

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Storage: Store at 2-8°C

InChIKey: ZGJUDTLSWZPIDW-MVFNBKNKSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=CC(=O)NC5=O

IUPAC Name: 3-[[(2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C39H47N4O8P/c1-27(2)43(28(3)4)52(49-24-10-22-40)51-34-25-37(42-23-21-36(44)41-38(42)45)50-35(34)26-48-39(29-11-8-7-9-12-29,30-13-17-32(46-5)18-14-30)31-15-19-33(47-6)20-16-31/h7-9,11-21,23,27-28,34-35,37H,10,24-26H2,1-6H3,(H,41,44,45)/t34-,35+,37+,52?/m0/s1

Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite]; 2'-Deoxy-5'-O-DMT-uridine 3'-CE Phosphoramidite; DMT-dU Phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1,2-dideoxy-1-uracil-1-yl-beta-D-erythro-pentofuranose; 3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine

5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite

Description: 5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite is a valuable compound primarily employed for the research and development of RNA molecules required for diagnostic purposes or therapeutic interventions. This compound plays a crucial role in the development of drugs targeting specific diseases and disorders, such as cancers or viral infections. It facilitates efficient nucleotide incorporation and ensures accurate development of RNA sequences.

CAT: BRP-00129

CAS: 163496-23-9

Molecular Formula: C45H61N4O9PSi

Molecular Weight: 861.05

Purity: ≥95%

Appearance: White, off-white to light yellow powder

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Storage: Storage at -20°C

InChIKey: JPJHNALDAAZFFN-LMNGBUJGSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)C2=CNC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C45H61N4O9PSi/c1-30(2)49(31(3)4)59(55-27-15-26-46)57-40-38(56-39(37-28-47-43(51)48-42(37)50)41(40)58-60(10,11)44(5,6)7)29-54-45(32-16-13-12-14-17-32,33-18-22-35(52-8)23-19-33)34-20-24-36(53-9)25-21-34/h12-14,16-25,28,30-31,38-41H,15,27,29H2,1-11H3,(H2,47,48,50,51)/t38-,39+,40-,41+,59?/m1/s1

Synonyms: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; PseudoUridine-CE Phosphoramidite; Pseudouridine CEP; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-beta-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione; 5'-O-DMTr-2'-O-TBDMS-Pseudouridine-3'-CE Phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-Pseudouridine-3'-cyanoethyl-Phosphoramidite

Phosphoramidochloridic acid, N,N-dimethyl-, [(2S,6R)-6-[6-(benzoylamino)-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester

Description: Phosphoramidochloridic acid, N,N-dimethyl-, [(2S,6R)-6-[6-(benzoylamino)-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester is a novel biomedical compound. With its unique molecular structure, it exhibits potential as a targeted therapeutic agent for treating various diseases.

CAT: BRP-00134

CAS: 956139-18-7

Molecular Formula: C38H37ClN7O4P

Molecular Weight: 722.17

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at -20 °C

Density: 1.34±0.1 g/cm3

InChIKey: HRNHOEBQNIMEGD-RJFDGRJRSA-N

CanonicalSMILES: CN(C)P(=O)(OCC1CN(CC(O1)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)Cl

IUPAC Name: N-[9-[(2R,6S)-6-[[chloro(dimethylamino)phosphoryl]oxymethyl]-4-tritylmorpholin-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C38H37ClN7O4P/c1-44(2)51(39,48)49-25-32-23-45(38(29-17-9-4-10-18-29,30-19-11-5-12-20-30)31-21-13-6-14-22-31)24-33(50-32)46-27-42-34-35(40-26-41-36(34)46)43-37(47)28-15-7-3-8-16-28/h3-22,26-27,32-33H,23-25H2,1-2H3,(H,40,41,43,47)/t32-,33+,51?/m0/s1

Synonyms: Morpholino A subunit; PMO-BzA; [(2S,6R)-6-[6-(Benzoylamino)-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl N,N-dimethylphosphoramidochloridate; N6-Bz protected A PMO Monomer

[(2S,6R)-6-{N4-Benzoylcydin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate

Description: This product is a potent inhibitor of Abl kinases and was developed for the treatment of chronic myeloid leukemia (CML). It works by blocking the activity of the Bcr-Abl fusion protein, which drives the growth of CML cells. Clinical trials have shown promising results, with high rates of complete remission and durable responses in patients with CML who were resistant or intolerant to previous treatments.

CAT: BRP-00135

CAS: 956139-21-2

Molecular Formula: C37H37ClN5O5P

Molecular Weight: 698.15

Purity: 97%

Appearance: White to off-white powder

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Storage: Store at -20 °C

Density: 1.30±0.1 g/cm3

InChIKey: RCQVHNTXMQCQLT-AUIRFOQBSA-N

CanonicalSMILES: CN(C)P(=O)(OCC1CN(CC(O1)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)C(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)Cl

IUPAC Name: N-[1-[(2R,6S)-6-[[chloro(dimethylamino)phosphoryl]oxymethyl]-4-tritylmorpholin-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C37H37ClN5O5P/c1-41(2)49(38,46)47-27-32-25-42(26-34(48-32)43-24-23-33(40-36(43)45)39-35(44)28-15-7-3-8-16-28)37(29-17-9-4-10-18-29,30-19-11-5-12-20-30)31-21-13-6-14-22-31/h3-24,32,34H,25-27H2,1-2H3,(H,39,40,44,45)/t32-,34+,49?/m0/s1

Synonyms: PMO-BzC; Morpholino C subunit; Phosphoramidochloridic acid, N,N-dimethyl-, [(2S,6R)-6-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester; [(2S,6R)-6-[4-(Benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methyl N,N-dimethylphosphoramidochloridate; N4-Bz protected C PMO Monomer

DyLight 5 CEP

Description: DyLight 5 CEP is a fluorescent dye used for oligonucleotide labeling.

CAT: BRP-00221

CAS: 182873-67-2

Molecular Formula: C60H72CIN4O4P

Molecular Weight: 979.68

Purity: 95%

Appearance: Blue to purple powder

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250 mg	$799	In stock

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Storage: Store at -20°C

InChIKey: GWCNEDQILVVBDJ-UHFFFAOYSA-M

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC[N+]1=C(C(C2=CC=CC=C21)(C)C)C=CC=CC=C3C(C4=CC=CC=C4N3CCCOC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=C(C=C7)OC)(C)C)OCCC#N.[Cl-]

IUPAC Name: 3-[[di(propan-2-yl)amino]-[3-[2-[5-[1-[3-[(4-methoxyphenyl)-diphenylmethoxy]propyl]-3,3-dimethylindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-1-yl]propoxy]phosphanyl]oxypropanenitrile;chloride

InChI: InChI=1S/C60H72N4O4P.ClH/c1-46(2)64(47(3)4)69(67-44-23-40-61)68-45-25-42-63-55-33-22-20-31-53(55)59(7,8)57(63)35-18-12-17-34-56-58(5,6)52-30-19-21-32-54(52)62(56)41-24-43-66-60(48-26-13-10-14-27-48,49-28-15-11-16-29-49)50-36-38-51(65-9)39-37-50;/h10-22,26-39,46-47H,23-25,41-45H2,1-9H3;1H/q+1;/p-1

Synonyms: Cy5 MMTr CE Phosphoramidite; 1-[3-(4-monomethoxytrityloxy)propyl]-1'-[3-[(2-cyanoethyl)-(N,N-diisopropylphosphoramidityl]propyl]-3,3,3',3'-tetramethylindodicarbocyanine chloride; Cyanine 5 Phosphoramidite

Related CAS: 351186-76-0 (free base)

Spacer Phosphoramidite 18 (BRP-00231)

Description: Spacer phosphoramidites 18 is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required.

CAT: BRP-00231

CAS: 125607-09-2

Molecular Formula: C42H61N2O10P

Molecular Weight: 784.93

Purity: 95%

Appearance: Colorless to light yellow oily matter

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Storage: Store at -20 °C

Boiling Point: 763.6±60.0 °C at 760 mmHg

InChIKey: ZTCKUVQHKIMCLI-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCCOCCOCCOCCOCCOCCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC

IUPAC Name: 3-[2-[2-[2-[2-[2-[2-[bis(4-methoxyphenyl)-phenylmethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C42H61N2O10P/c1-35(2)44(36(3)4)55(53-22-10-21-43)54-34-32-51-30-28-49-26-24-47-23-25-48-27-29-50-31-33-52-42(37-11-8-7-9-12-37,38-13-17-40(45-5)18-14-38)39-15-19-41(46-6)20-16-39/h7-9,11-20,35-36H,10,22-34H2,1-6H3

Synonyms: 1,1-Bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite; Spacer C18 CE Phosphoramidite; Spacer 18 Amidite; Hexaethylene glycol phosphoramidite; 18-O-(4,4'-Dimethoxytrityl)-hexaethylene glycol-1-[[(2-cyanoethyl)-(N,N-diisopropyl)]-Phosphoramidite; Spacer 18 Phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 19,19-bis(4-methoxyphenyl)-19-phenyl-3,6,9,12,15,18-hexaoxanonadec-1-yl 2-cyanoethyl ester; 19,19-Bis(4-methoxyphenyl)-19-phenyl-3,6,9,12,15,18-hexaoxanonadec-1-yl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; DMT Hexaethylene Glycol phosphoramidite

2'-tBDSilyl Adenosine (n-PAC) CED phosphoramidite

Description: 2'-tBDSilyl Adenosine (n-PAC) CED Phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It incorporates a 2'-tert-butyldimethylsilyl (tBDSilyl) group onto the adenosine (A) nucleoside at the 2'-position. Additionally, it features a nitrilotriacetic acid (n-PAC) group for chelating metal ions and a controlled-efficiency (CED) phosphoramidite for efficient incorporation during solid-phase synthesis. This reagent enables the production of modified RNA oligonucleotides with improved stability and functionality, suitable for various molecular biology and biotechnology applications, including RNA interference and gene expression studies.

CAT: BRP-00233

CAS: 121058-86-4

Molecular Formula: C54H68N7O9PSi

Molecular Weight: 1018.22

Purity: 95%

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InChIKey: DBCNFFIOULAURJ-NMRDYAFNSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=NC3=C(N=CN=C32)NC(=O)COC4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]-2-phenoxyacetamide

InChI: InChI=1S/C54H68N7O9PSi/c1-37(2)61(38(3)4)71(67-32-18-31-55)69-48-45(33-66-54(39-19-14-12-15-20-39,40-23-27-42(63-8)28-24-40)41-25-29-43(64-9)30-26-41)68-52(49(48)70-72(10,11)53(5,6)7)60-36-58-47-50(56-35-57-51(47)60)59-46(62)34-65-44-21-16-13-17-22-44/h12-17,19-30,35-38,45,48-49,52H,18,32-34H2,1-11H3,(H,56,57,59,62)/t45-,48-,49-,52-,71?/m1/s1

Synonyms: PAC-rA CEP; N-blocked-5'-O-DMT-2'-O-TBDMS CED adenosine phosphoramidite; (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-Dimethoxytrityl-N-phenoxyacetyl-Adenosine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(phenoxyacetyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; Pac-A-CE phosphoramidite; rA (Pac) CE-Phosphoramidite; 2'-TBDMS Adenosine (n-PAC) CED phosphoramidite

Chemical Phosphorylation Reagent II

Description: N,N-diisopropylphosphoramidite, a catalytic compound, is an essential building block for oligonucleotide synthesis used in various therapeutic domains such as antisense therapy, siRNA, and gene editing. This efficient and highly pure chemical ensures the production of top-quality therapeutic oligonucleotides.

CAT: BRP-00237

CAS: 171285-25-9

Molecular Formula: C39H51N2O9P

Molecular Weight: 722.80

Purity: ≥95%

Appearance: Colorless semisolid

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Storage: Store at -20 °C

Boiling Point: 740.0±60.0°C at 760 mmHg

InChIKey: IEKIULVSVQLVMS-UHFFFAOYSA-N

CanonicalSMILES: CCOC(=O)C(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)(COP(N(C(C)C)C(C)C)OCCC#N)C(=O)OCC

IUPAC Name: diethyl 2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-2-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]propanedioate

InChI: InChI=1S/C39H51N2O9P/c1-9-46-36(42)38(37(43)47-10-2,28-50-51(49-26-14-25-40)41(29(3)4)30(5)6)27-48-39(31-15-12-11-13-16-31,32-17-21-34(44-7)22-18-32)33-19-23-35(45-8)24-20-33/h11-13,15-24,29-30H,9-10,14,26-28H2,1-8H3

Synonyms: O-DMT-2,2-di(ethoxycarbonyl)propan-1,3-diol; CPⅡ; CPRII; 2-[(4,4'-Dimethoxytrityloxy)methyl]-2-[[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]methyl]malonic acid diethyl ester; 3-(4,4'-dimethoxytrityloxy)-2,2-dicarboxyethyl]propyl(2-cyanoethyl)(N, N-diisopropyl)phosphoramidite; (2-Cyanoethyl) (2,2-bis(ethoxycarbonyl)-3-(4,4'-dimethoxytrityloxy)propyl-1) N,N-diisopropylphosphoramidite

2-O-DMT-sulfonyldiethanol phosphoramidite

Description: 2-O-DMT-sulfonyldiethanol phosphoramidite substantiates its inevitable prowess in the synthesis and alteration of nucleic acids across diverse applications. Unparalleled in its chemical composition, this exceptional concoction facilitates meticulous and efficient manipulation of nucleic acids, thus fostering elevated biomedical exploration with incomparable precision.

CAT: BRP-00249

CAS: 108783-02-4

Molecular Formula: C34H45N2O7PS

Molecular Weight: 656.77

Purity: >95% by HPLC

Appearance: Light-yellow Oil

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10 g	$1299	In stock

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Storage: store at -20 °C

Boiling Point: 717.4±60.0 °C at 760 mmHg

InChIKey: RJDYWMSSNMDIOO-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCCS(=O)(=O)CCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC

IUPAC Name: 3-[2-[2-[bis(4-methoxyphenyl)-phenylmethoxy]ethylsulfonyl]ethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C34H45N2O7PS/c1-27(2)36(28(3)4)44(42-22-10-21-35)43-24-26-45(37,38)25-23-41-34(29-11-8-7-9-12-29,30-13-17-32(39-5)18-14-30)31-15-19-33(40-6)20-16-31/h7-9,11-20,27-28H,10,22-26H2,1-6H3

Synonyms: 2-((2-(bis(4-methoxyphenyl)(phenyl)methoxy)ethyl)sulfonyl)ethyl (2-cyanoethyl) diisopropylphosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-[[2-[bis(4-methoxyphenyl)phenylmethoxy]ethyl]sulfonyl]ethyl 2-cyanoethyl ester; 2-[2-(4,4'-dimethoxytrityloxy)ethylsulfonyl]ethyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 2-O-DMT-S phosphoramidite; 5'-Phosphate-Amidite; O-DMT-2,2'-sulfonyldiethanol phosphoramidite; 5'-Phosphate-ON Reagent

Solid Chemical phosphorylation reagent II

Description: Solid Chemical phosphorylation reagent II is a click chemistry reagent for the synthesis of oligonucleotides possessing 5'-terminal phosphate residues.

CAT: BRP-00250

CAS: 202284-84-2

Molecular Formula: C37H49N4O7P

Molecular Weight: 692.79

Purity: ≥95%

Appearance: Off-white Solid

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250 mg	$299	In stock

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Storage: Store at -20°C

InChIKey: HAUCJKGKHJPPNN-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)(C(=O)NC)C(=O)NC

IUPAC Name: 2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-2-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]-N,N'-dimethylpropanediamide

InChI: InChI=1S/C37H49N4O7P/c1-27(2)41(28(3)4)49(47-24-12-23-38)48-26-36(34(42)39-5,35(43)40-6)25-46-37(29-13-10-9-11-14-29,30-15-19-32(44-7)20-16-30)31-17-21-33(45-8)22-18-31/h9-11,13-22,27-28H,12,24-26H2,1-8H3,(H,39,42)(H,40,43)

Synonyms: Chemical phosphorylation amidite; [3-(4,4'-Dimethoxytrityloxy)-2,2-dicarboxymethylamido]propyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-(methylamino)-2-[(methylamino)carbonyl]-3-oxopropyl 2-cyanoethyl ester; Solid Chemical Phosphorylation Reagent 2; 2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(methylamino)-2-(methylcarbamoyl)-3-oxopropyl(2-cyanoethyl)(N,N-diisopropyl)phosphoramidite

6-FAM-DMT-phosphoramidite

Description: 6-FAM-DMT Phosphoramidite is a phosphoramidite derivative used to introduce 6-carboxyfluorescein (6-FAM) into oligonucleotides during solid-phase synthesis. It includes a 6-FAM fluorophore and a dimethoxytrityl (DMT) protecting group, which facilitates efficient incorporation and subsequent deprotection during synthesis. This reagent enables the production of fluorescently labeled oligonucleotides for applications such as fluorescence-based detection, quantitative PCR (qPCR), and fluorescence resonance energy transfer (FRET) assays.

CAT: BRP-00259

CAS: 316121-60-5

Molecular Formula: C68H78N3O13P

Molecular Weight: 1176.33

Purity: 95%

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Storage: Store at 2-8 °C

InChIKey: ODJKPDRSCITVNU-UHFFFAOYNA-N

Solubility: Soluble in Anhydrous Acetonitrile

CanonicalSMILES: COC1=CC=C(C=C1)C(OCC(CCCCNC(=O)C1=CC=C2C(=O)OC3(C2=C1)C1=CC=C(OC(=O)C(C)(C)C)C=C1OC1=CC(OC(=O)C(C)(C)C)=CC=C31)COP(OCCC#N)N(C(C)C)C(C)C)(C1=CC=CC=C1)C1=CC=C(OC)C=C1

IUPAC Name: [6-[[5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]carbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate

InChI: InChI=1/C68H78N3O13P/c1-44(2)71(45(3)4)85(79-38-18-36-69)80-43-46(42-78-67(48-20-14-13-15-21-48,49-23-27-51(76-11)28-24-49)50-25-29-52(77-12)30-26-50)19-16-17-37-70-61(72)47-22-33-55-58(39-47)68(84-62(55)73)56-34-31-53(81-63(74)65(5,6)7)40-59(56)83-60-41-54(32-35-57(60)68)82-64(75)66(8,9)10/h13-15,20-35,39-41,44-46H,16-19,37-38,42-43H2,1-12H3,(H,70,72)

Synonyms: 6-Fluorescein Phosphoramidite; 2-Dimethoxytrityloxymethyl-6-(3',6'-dipivaloylfluorescein-6-yl-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-6-Fluorescein phosphoramidite (with DMT); Propanoic acid, 2,2-dimethyl-, 6-[7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; DMT-6-FAM phosphoramidite

Alkyne-Modifier Serinol Phosphoramidite

Description: Alkyne-Modifier Serinol Phosphoramidite is a potent chemical reagent that pervasively aids in the synthesis of oligonucleotides for biomedical research purposes. Its proficiency lies in the assortment, stability, solubility enhancement and augmented bioavailability of DNA and RNA modification. Not only that, it proficiently gets the job done in developing gene therapies with targeted drug delivery systems for treating ailments like cancer, viral infections, and genetic disorders.

CAT: BRP-00264

CAS: 2084118-98-7

Molecular Formula: C42H55N4O7P

Molecular Weight: 758.88

Purity: 95%

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250 mg	$498	In stock
1 g	$1498	In stock

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Storage: Store at -20°C

InChIKey: AGVCOEQZDILAFH-UHFFFAOYSA-N

Solubility: Soluble in Anhydrous Acetonitrile

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)NC(=O)CCNC(=O)CCCC#C

IUPAC Name: N-[3-[[1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]amino]-3-oxopropyl]hex-5-ynamide

InChI: InChI=1S/C42H55N4O7P/c1-8-9-11-17-40(47)44-28-26-41(48)45-37(31-53-54(52-29-14-27-43)46(32(2)3)33(4)5)30-51-42(34-15-12-10-13-16-34,35-18-22-38(49-6)23-19-35)36-20-24-39(50-7)25-21-36/h1,10,12-13,15-16,18-25,32-33,37H,9,11,14,17,26,28-31H2,2-7H3,(H,44,47)(H,45,48)

Synonyms: 3-Dimethoxytrityloxy-2-(3-(5-hexynamido)propanamido)propyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 3-[bis(4-methoxyphenyl)phenylmethoxy]-2-[[1-oxo-3-[(1-oxo-5-hexyn-1-yl)amino]propyl]amino]propyl 2-cyanoethyl ester; 3-[Bis(4-methoxyphenyl)phenylmethoxy]-2-[[1-oxo-3-[(1-oxo-5-hexyn-1-yl)amino]propyl]amino]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite

Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite

Description: A useful phosphorylating reagent.

CAT: BRP-00308

CAS: 102690-88-0

Molecular Formula: C12H22N3O2P

Molecular Weight: 271.30

Purity: 96%

Appearance: Yellow Liquid

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5 g	$199	In stock
25 g	$733	In stock

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Storage: Store at -20°C under inert atmosphere

Density: 1.039 g/mL at 25°C

Boiling Point: 335.3±27.0°C (Predicted)

InChIKey: LDHWBEHZLFDXCU-UHFFFAOYSA-N

Solubility: Soluble in Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCCC#N

IUPAC Name: 3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C12H22N3O2P/c1-11(2)15(12(3)4)18(16-9-5-7-13)17-10-6-8-14/h11-12H,5-6,9-10H2,1-4H3

Synonyms: N,N-bis(1-Methylethyl)phosphoramidous acid bis(2-cyanoethyl) ester; Bis(2-cyanoethyl) diisopropylphosphoramidite; Bis(2-cyanoethoxy)(diisopropylamino)phosphine; Bis(2-cyanoethoxy)-N,N-diisopropylaminophosphine; Phosphoramidous acid, bis(1-methylethyl)-, bis(2-cyanoethyl) ester; Phosphoramidous acid, N,N-bis(1-methylethyl)-, bis(2-cyanoethyl) ester; Bis-cyanoethyl-N,N-diisopropyl CED phosphoramidite

5'-POM-(E)-vinyl phosphonate-2'-O-Me-U-3'-CE-Phosphoramidite

Description: 5'-POM-(E)-vinyl phosphonate-2'-O-Me-U-3'-CE-Phosphoramidite is a sophisticated biochemical utilized in the pharmaceutical industry. This molecule plays a vital role in the synthesis of antiviral medications targeted at treating diseases like Hepatitis C.

CAT: BRP-00319

CAS: 2172373-55-4

Molecular Formula: C32H52N4O13P2

Molecular Weight: 762.72

Purity: ≥98%

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Storage: Store at -20 °C

InChIKey: AJJPYIXDIHURAB-FQIYNDLNSA-N

CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=CC(=O)NC2=O)C1OC)C=CP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)N(C(C)C)C(C)C

IUPAC Name: ((((E)-2-((2R,3R,4R,5R)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)

InChI: InChI=1S/C32H52N4O13P2/c1-21(2)36(22(3)4)50(45-17-12-15-33)49-25-23(48-27(26(25)42-11)35-16-13-24(37)34-30(35)40)14-18-51(41,46-19-43-28(38)31(5,6)7)47-20-44-29(39)32(8,9)10/h13-14,16,18,21-23,25-27H,12,17,19-20H2,1-11H3,(H,34,37,40)/b18-14+/t23-,25-,26-,27-,50?/m1/s1

Synonyms: 5'-POM-vinyl phosphonate, 2'-OMe-U CEP; 2,4(1H,3H)-Pyrimidinedione, 1-[(5E)-6-[bis[(2,2-dimethyl-1-oxopropoxy)methoxy]phosphinyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5,6-dideoxy-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]-; 1-[(5E)-6-[Bis[(2,2-dimethyl-1-oxopropoxy)methoxy]phosphinyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5,6-dideoxy-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]-2,4(1H,3H)-pyrimidinedione; 5'-POM-(E)-vinyl phosphonate-2'-O-Me-rU-3'-CE-Phosphoramidite; (E)-5'-VP-2'-OMe-U-CE-Phosphoramidite; 5'-(E)-VP-2'-OMe-U Phosphoramidite

2'-O-Propargyl A(Bz)-3'-phosphoramidite

Description: 2'-O-Propargyl A(Bz)-3'-phosphoramidite, a highly versatile compound, plays a pivotal role in the biomedical sector for crafting customized oligonucleotides. Its exceptional propargyl and benzoyl functionalities facilitate seamless bonding with a wide range of biomolecules. Hailed for its profound impact in drug discovery, this product aids in the creation of nucleic acid-driven therapeutics, notably those combating diverse ailments such as cancer, viral infections, and neurodegenerative disorders. Its paramount significance in the field underscores the significance of this remarkable compound.

CAT: BRP-00320

CAS: 171486-59-2

Molecular Formula: C50H54N7O8P

Molecular Weight: 911.98

Purity: ≥95%

Appearance: White, off-white to faint yellow powder

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500 mg	$519	In stock

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Storage: Store at -20 °C

InChIKey: ZNKFQCJEZKZIPC-XOMUZYEBSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCC#C)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-prop-2-ynoxyoxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C50H54N7O8P/c1-8-29-61-45-44(65-66(63-30-15-28-51)57(34(2)3)35(4)5)42(64-49(45)56-33-54-43-46(52-32-53-47(43)56)55-48(58)36-16-11-9-12-17-36)31-62-50(37-18-13-10-14-19-37,38-20-24-40(59-6)25-21-38)39-22-26-41(60-7)27-23-39/h1,9-14,16-27,32-35,42,44-45,49H,15,29-31H2,2-7H3,(H,52,53,55,58)/t42-,44-,45-,49-,66?/m1/s1

Synonyms: N4-Bz-5'-O-DMTr-2'-O-propargyladenosine-3'-CED-phosphoramidite; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyladenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propyn-1-yl-adenosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N-Benzoyl-2'-O-(2-propynyl)-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-5'-O-[phenylbis(4-methoxyphenyl)methyl]adenosine; DMTr-2'-O-propargyl-rA(Bz)-3'-CE-Phosphoramidite; 2'-O-propargyl Adenosine (n-bz) CED phosphoramidite; N6-Bz-DMT-2'-O-propargyl-A-CE-Phosphoramidite; [N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-adenosine]-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite

CAL Fluor Red 610 CE Phosphoramidite

Description: CAL Fluor Red 610 CE Phosphoramidite, a highly sensitive and reliable fluorescent dye, is commonly applied for the real-time PCR detection and quantification of nucleic acid targets relevant to the diagnosis and management of various diseases, including cancer and viral infections, rendering it an indispensable asset to the biomedical research community and clinical diagnostic industry.

CAT: BRP-00474

CAS: 861143-34-2

Molecular Formula: C46H57N5O4P2F6P

Molecular Weight: 919.93

Purity: 95%

Appearance: Red Solid

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250 mg	$699	In stock

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Storage: Store at -20°C

InChIKey: AREDCQVONVVIKP-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CCN(CC1)C(=O)C2=CC=CC=C2C3=C4C=C5CCC[N+]6=C5C(=C4OC7=C3C=C8CCCN9C8=C7CCC9)CCC6.F[P-](F)(F)(F)(F)F

IUPAC Name: 3-[[di(propan-2-yl)amino]-[1-[2-(3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaen-16-yl)benzoyl]piperidin-4-yl]oxyphosphanyl]oxypropanenitrile;hexafluorophosphate

InChI: InChI=1S/C46H57N5O4P.F6P/c1-30(2)51(31(3)4)56(53-27-11-20-47)55-34-18-25-50(26-19-34)46(52)36-15-6-5-14-35(36)41-39-28-32-12-7-21-48-23-9-16-37(42(32)48)44(39)54-45-38-17-10-24-49-22-8-13-33(43(38)49)29-40(41)45;1-7(2,3,4,5)6/h5-6,14-15,28-31,34H,7-13,16-19,21-27H2,1-4H3;/q+1;-1

Synonyms: 1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium, 9-[2-[[4-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]-1-piperidinyl]carbonyl]phenyl]-2,3,6,7,12,13,16,17-octahydro-, hexafluorophosphate(1-) (1:1); CAL Fluor Red 610 Amidite; CAL Fluor Red 610; CFR 610 Amidite

8-Azanebularine CE-Phosphoramidite

Description: DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite is a chemical compound used in oligonucleotide synthesis. It protects the 5'-hydroxyl group with a DMTr group and stabilizes the ribose sugar with a 2'-O-TBDMS modification. Additionally, it incorporates 8-azanebularine as a modified nucleoside. The 3'-CE phosphoramidite facilitates nucleotide addition during synthesis. This compound allows for the controlled synthesis of oligonucleotides with specific modifications, important for various applications in molecular biology and biotechnology.

CAT: BRP-00557

CAS: 771494-03-2

Molecular Formula: C45H60N7O7PSi

Molecular Weight: 870.08

Purity: ≥95%

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50 mg	$699	In stock
250 mg	$2399	In stock

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Storage: Store at -20 °C

Boiling Point: 827.8±65.0 °C (Predicted)

InChIKey: QEYQVSAEEYPGQB-IEXCOMMKSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](N2C3=NC=NC=C3N=N2)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6

IUPAC Name: (2R,3R,4R,5R)-5-(3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C45H60N7O7PSi/c1-31(2)52(32(3)4)60(56-27-15-26-46)58-40-39(57-43(41(40)59-61(10,11)44(5,6)7)51-42-38(49-50-51)28-47-30-48-42)29-55-45(33-16-13-12-14-17-33,34-18-22-36(53-8)23-19-34)35-20-24-37(54-9)25-21-35/h12-14,16-25,28,30-32,39-41,43H,15,27,29H2,1-11H3/t39-,40-,41-,43-,60?/m1/s1

Synonyms: DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite

5'-O-DMTr-2'-OMeU-methylphosphonamidite

Description: 5'-O-DMTr-2'-OMeU-methylphosphonamidite is an indispensable recompound widely employed in the field of compound, exhibiting immense significance in the research and development of altered oligonucleotides meticulously crafted for gene therapy and medicinal chemistry. Moreover, it assumes a pivotal role in the research and development of antisense oligonucleotides explicitly engineered to combat genetic disorders, infectious ailments and select malignancies.

CAT: BRP-01610

CAS: 191786-64-8

Molecular Formula: C38H48N3O8P

Molecular Weight: 705.78

Purity: ≥95%

Appearance: Off-white solid

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10 mg	$499	In stock

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Storage: Store at -20 °C

InChIKey: OMQYBRGCCIXKCN-IFQFNZHASA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: CC(C)N(C(C)C)P(C)OC1C(OC(C1OC)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[[di(propan-2-yl)amino]-methylphosphanyl]oxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C38H48N3O8P/c1-25(2)41(26(3)4)50(8)49-34-32(48-36(35(34)46-7)40-23-22-33(42)39-37(40)43)24-47-38(27-12-10-9-11-13-27,28-14-18-30(44-5)19-15-28)29-16-20-31(45-6)21-17-29/h9-23,25-26,32,34-36H,24H2,1-8H3,(H,39,42,43)/t32-,34-,35-,36-,50?/m1/s1

Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[P-methyl-N,N-bis(1-methylethyl)phosphonamidite]; 5'-O-DMTr-2'-O-methyluridine-3'-O-(P-methyl-N,N-diisopropylamino)phosphonamidite; 2'-OMe U Me-amidite; 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((diisopropylamino)(methyl)phosphaneyl)oxy)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-DMTr-2'-OMe-U-3'-O-[P-methyl-(N,N-diisopropyl)]-Phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-OMe-uridine-3'-O-[P-methyl-(N,N-diisopropyl)]-Phosphoramidite; 2'-O-Methyl Uridine p-methyl phosphonamidite

5'-O-DMT-2'-O-TBDMS-2-Thiouridine 3'-CE phosphoramidite

Description: 5'-O-DMT-2'-O-TBDMS-2-Thiouridine 3'-CE phosphoramidite is a phosphoramidite derivative used for the solid-phase research and development of modified RNA sequences. With its 5'-O-DMT protection, 2'-O-TBDMS modification and 2-thiouridine incorporation, it enables the controlled research and development of RNA molecules for studying RNA-protein interactions and RNA-based therapeutics targeting diseases like cancer and viral infections.

CAT: BRP-01626

CAS: 163496-21-7

Molecular Formula: C45H61N4O8PSSi

Molecular Weight: 877.11

Purity: >95%

Appearance: Off-white solid

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1 g	$7980	In stock

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Storage: Store at -20 °C

InChIKey: BLKYMIQDVIRXHA-OHKMQFRXSA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=CC(=O)NC2=S)C1O[Si](C)(C)C(C)(C)C)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C

IUPAC Name: 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-(4-oxo-2-sulfanylidenepyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C45H61N4O8PSSi/c1-31(2)49(32(3)4)58(54-29-15-27-46)56-40-38(55-42(48-28-26-39(50)47-43(48)59)41(40)57-60(10,11)44(5,6)7)30-53-45(33-16-13-12-14-17-33,34-18-22-36(51-8)23-19-34)35-20-24-37(52-9)25-21-35/h12-14,16-26,28,31-32,38,40-42H,15,29-30H2,1-11H3,(H,47,50,59)/t38-,40-,41-,42-,58?/m1/s1

Synonyms: 2'-OTBS 2-Thio-U amidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-2-thio-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-2-thio-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

2'-OMe-dmf-G-CE Phosphoramidite

5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite

5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite

Phosphoramidochloridic acid, N,N-dimethyl-, [(2S,6R)-6-[6-(benzoylamino)-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester

[(2S,6R)-6-{N4-Benzoylcydin-1-yl}-4-tritylmorpholin-2-yl]methyl dimethyl-phosphoramidochloridate

DyLight 5 CEP

Spacer Phosphoramidite 18 (BRP-00231)

2'-tBDSilyl Adenosine (n-PAC) CED phosphoramidite

Chemical Phosphorylation Reagent II

2-O-DMT-sulfonyldiethanol phosphoramidite

Solid Chemical phosphorylation reagent II

6-FAM-DMT-phosphoramidite

Alkyne-Modifier Serinol Phosphoramidite

Bis(2-cyanoethyl)-N,N-diisopropylphosphoramidite

5'-POM-(E)-vinyl phosphonate-2'-O-Me-U-3'-CE-Phosphoramidite

2'-O-Propargyl A(Bz)-3'-phosphoramidite

CAL Fluor Red 610 CE Phosphoramidite

8-Azanebularine CE-Phosphoramidite

5'-O-DMTr-2'-OMeU-methylphosphonamidite

5'-O-DMT-2'-O-TBDMS-2-Thiouridine 3'-CE phosphoramidite

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