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Phosphoramidites

2'-Modified Phosphoramidites
(594/594)
2'-Phosphoramidites
(27/27)
3'-Modified Phosphoramidites
(246/246)
5'-Modified Phosphoramidites
(79/79)
Arabino Phosphoramidites
(24/24)
Base Protected Phosphoramidites (469/469) Dye Phosphoramidites
(72/72)
Label Phosphoramidites
(86/86)
Linker Phosphoramidites
(113/113)
Other Phosphoramidites
(94/94)
PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12)
Reverse Phosphoramidites
(25/25)
Spacer Phosphoramidites
(24/24)
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6-Hexachloro-Fluorescein Phosphoramidite (BRP-02228)

6-Hexachloro-Fluorescein Phosphoramidite (BRP-02228)

Description: A HEX phosphoramidite for yellow-green fluorescent oligonucleotides. Perfect for multiplex qPCR and genotyping assays.
CAT: BRP-02228
CAS: 1360547-55-2
Molecular Formula: C46H52N3O10Cl6P
Molecular Weight: 1050.61
Purity: ≥95%
Appearance: Off-white Solid
Size Price Stock Quantity
1 g $1449 In stock
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Storage: Store at -20 °C
Boiling Point: 928.7±65.0 °C at 760 mmHg
Symbol: 6-HEX Phosphoramidite; 5'-Hexachloro-Fluorescein-CE Phosphoramidite (HEX)
InChIKey: RDZTYXJTMDFAOO-UHFFFAOYSA-N
Fluorescence Maximum: 549
Absorption Maximum (Lambda Max): 533
Solubility: Soluble in Acetonitrile, DCM
SMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)C1=CC(=C2C(=C1Cl)C3(C4=CC(=C(C(=C4OC5=C(C(=C(C=C53)Cl)OC(=O)C(C)(C)C)Cl)Cl)OC(=O)C(C)(C)C)Cl)OC2=O)Cl)OCCC#N
IUPAC Name: [2',4,4',5',7,7'-hexachloro-6-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C46H52Cl6N3O10P/c1-23(2)55(24(3)4)66(61-19-15-16-53)60-18-14-12-11-13-17-54-40(56)25-20-28(47)31-32(33(25)50)46(65-41(31)57)26-21-29(48)38(63-42(58)44(5,6)7)34(51)36(26)62-37-27(46)22-30(49)39(35(37)52)64-43(59)45(8,9)10/h20-24H,11-15,17-19H2,1-10H3,(H,54,56)
Synonyms: HEX phosphoramidite, 6-isomer; DyLight HEX CEP; 6-(4,7,2',4',5',7'-Hexachloro-3',6'-dipivaloylfluoresceinyl-6-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Propanoic acid, 2,2-dimethyl-, 1,1'-[6-[10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-2',4,4',5',7,7'-hexachloro-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] ester; 1,1'-[6-[10-[Bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-2',4,4',5',7,7'-hexachloro-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] bis(2,2-dimethylpropanoate); Hex-C6-amidite
Cyanine 3 Phosphoramidite (BRP-02234)

Cyanine 3 Phosphoramidite (BRP-02234)

Description: Cyanine 3 Phosphoramidite is a trusted fluorescent phosphoramidite dye for DNA and RNA oligonucleotide labeling. It ensures high fluorescence yield and excellent coupling efficiency for genetic analysis.
CAT: BRP-02234
CAS: 718594-66-2
Molecular Formula: C58H70N4O4P
Molecular Weight: 918.17
Purity: >95%
Appearance: Red Solid
Size Price Stock Quantity
500 mg $1999 In stock
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Storage: Store at -20 °C
Symbol: Cy3 Phosphoramidite
InChIKey: NLVDKXRBDBBNMO-UHFFFAOYSA-N
SMILES: CC(C)N(C(C)C)P(OCCC[N+]1=C(C(C2=CC=CC=C21)(C)C)C=CC=C3C(C4=CC=CC=C4N3CCCOC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=C(C=C7)OC)(C)C)OCCC#N
IUPAC Name: 3-[[di(propan-2-yl)amino]-[3-[2-[3-[1-[3-[(4-methoxyphenyl)-diphenylmethoxy]propyl]-3,3-dimethylindol-2-ylidene]prop-1-enyl]-3,3-dimethylindol-1-ium-1-yl]propoxy]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C58H70N4O4P/c1-44(2)62(45(3)4)67(65-42-21-38-59)66-43-23-40-61-53-31-19-17-29-51(53)57(7,8)55(61)33-20-32-54-56(5,6)50-28-16-18-30-52(50)60(54)39-22-41-64-58(46-24-12-10-13-25-46,47-26-14-11-15-27-47)48-34-36-49(63-9)37-35-48/h10-20,24-37,44-45H,21-23,39-43H2,1-9H3/q+1
Synonyms: 2-[3-[1,3-Dihydro-1-[3-(4-methoxytriphenylmethoxy)propyl]-3,3-dimethyl-2H-indol-2-ylidene]-1-propen-1-yl]-1-[3-[N,N-diisopropylamino(2-cyanoethoxy)phosphinoxy]propyl]-3,3-dimethyl-3H-indolium; 2-[3-[1-[3-[[[Bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1-propen-1-yl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-3H-indolium; 3H-Indolium, 2-[3-[1-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1-propenyl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-; 2-(3-(1-(3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)propyl)-3,3-dimethylindolin-2-ylidene)prop-1-en-1-yl)-1-(3-((4-methoxyphenyl)diphenylmethoxy)propyl)-3,3-dimethyl-3H-indol-1-ium
Related CAS: 182873-76-3 (chloride salt)
Cyanine 5 Phosphoramidite (BRP-02235)

Cyanine 5 Phosphoramidite (BRP-02235)

Description: Cyanine 5 Phosphoramidite is a red-emitting fluorescent phosphoramidite used in DNA synthesis and FRET assays. It provides intense signal and superior purity for molecular diagnostics.
CAT: BRP-02235
CAS: 351186-76-0
Molecular Formula: C60H72N4O4P
Molecular Weight: 944.21
Purity: >95%
Appearance: Blue Solid
Size Price Stock Quantity
250 mg $838 In stock
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Storage: Store at -20 °C
Symbol: Cy5 Phosphoramidite
InChIKey: WQVYZWOFBGLVGB-UHFFFAOYSA-N
SMILES: CC(C)N(C(C)C)P(OCCC[N+]1=C(C(C2=CC=CC=C21)(C)C)C=CC=CC=C3C(C4=CC=CC=C4N3CCCOC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=C(C=C7)OC)(C)C)OCCC#N
IUPAC Name: 3-[[di(propan-2-yl)amino]-[3-[2-[5-[1-[3-[(4-methoxyphenyl)-diphenylmethoxy]propyl]-3,3-dimethylindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-1-yl]propoxy]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C60H72N4O4P/c1-46(2)64(47(3)4)69(67-44-23-40-61)68-45-25-42-63-55-33-22-20-31-53(55)59(7,8)57(63)35-18-12-17-34-56-58(5,6)52-30-19-21-32-54(52)62(56)41-24-43-66-60(48-26-13-10-14-27-48,49-28-15-11-16-29-49)50-36-38-51(65-9)39-37-50/h10-22,26-39,46-47H,23-25,41-45H2,1-9H3/q+1
Synonyms: 2-[5-[1,3-Dihydro-1-[3-(4-methoxytriphenylmethoxy)propyl]-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-[3-[N,N-diisopropylamino(2-cyanoethoxy)phosphinoxy]propyl]-3,3-dimethyl-3H-indolium; 3H-Indolium, 2-[5-[1-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-; 2-[5-[1-[3-[[[Bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-3H-indolium; 3H-Indolium, 2-[5-[1-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadienyl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-
Related CAS: 182873-67-2 (chloride salt)
Quasar 670 CE Phosphoramidite (BRP-02352)

Quasar 670 CE Phosphoramidite

Description: Quasar 670 dyes are cyanine derivatives of Cyanine 5. Cyanine dyes are a popular oligonucleotide modification and are commonly used for imaging, flow cytometry, and genomic applications.
CAT: BRP-02352
CAS: 1032678-33-3
Molecular Formula: C47H67F6N5O2P2
Molecular Weight: 910.02
Purity: 95%
Size Price Stock Quantity
250 mg $699 In stock
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InChIKey: CXTKSIZCEDZHOE-PVMSMBLDNA-O
SMILES: [P+5]([F-])([F-])([F-])([F-])([F-])[F-].C(CCCCC(N[C@@H]1CC[C@@H](OP(N(C(C)C)C(C)C)CCC#N)CC1)=O)N2C=3C(C(C)(C)C2=CC=CC=CC4=[N+](C)C=5C(C4(C)C)=CC=CC5)=CC=CC3
IUPAC Name: 1-(6-(((1r,4r)-4-(((2-cyanoethyl)(diisopropylamino)phosphaneyl)oxy)cyclohexyl)amino)-6-oxohexyl)-3,3-dimethyl-2-(5-(1,3,3-trimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-3H-indol-1-ium;hexafluorophosphate
InChI: InChI=1/C47H66N5O2P.F6P/c1-35(2)52(36(3)4)55(34-20-32-48)54-38-30-28-37(29-31-38)49-45(53)27-14-11-19-33-51-42-24-18-16-22-40(42)47(7,8)44(51)26-13-10-12-25-43-46(5,6)39-21-15-17-23-41(39)50(43)9;1-7(2,3,4,5)6/h10,12-13,15-18,21-26,35-38H,11,14,19-20,27-31,33-34H2,1-9H3;/q;-1/p+1/t37-,38-,55?;
Synonyms: 3H-Indolium, 2-[5-[1-[6-[[trans-4-[[[bis(1-methylethyl)amino](2-cyanoethyl)phosphino]oxy]cyclohexyl]amino]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1,3,3-trimethyl-, hexafluorophosphate(1-) (1:1)
Related CAS: 1032678-32-2 (free base)
Biotin-dT CE-Phosphoramidite (BRP-02358)

Biotin-dT CE-Phosphoramidite

Description: Biotin-dT CE-Phosphoramidite is a prestigious compound, engaged in the critical tasks of labeling and detecting DNA or RNA sequences. With the amalgamation of biotin, this meticulously modified nucleotide engenders a realm of convenience for meticulous purification processes, unrivaled amplification endeavors and captivating visualization techniques.
CAT: BRP-02358
CAS: 198080-40-9
Molecular Formula: C69H89N8O12PS
Molecular Weight: 1285.55
Purity: 95%
Appearance: White, off-white to light yellow powder
Size Price Stock Quantity
250 mg $580 In stock
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Storage: Store at -20 °C
InChIKey: FHABSPMZQJOPSS-GGVSAJPNSA-N
Solubility: Soluble in Anhydrous Acetonitrile
SMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C=CC(=O)NCCCCCCNC(=O)CCCCC6C7C(CS6)N(C(=O)N7)C(=O)C8=CC=C(C=C8)C(C)(C)C
IUPAC Name: 5-[(3aR,6S,6aS)-3-(4-tert-butylbenzoyl)-2-oxo-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]-N-[6-[3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoylamino]hexyl]pentanamide
InChI: InChI=1S/C69H89N8O12PS/c1-46(2)77(47(3)4)90(87-41-19-38-70)89-57-42-62(88-58(57)44-86-69(51-20-13-12-14-21-51,52-29-33-54(84-8)34-30-52)53-31-35-55(85-9)36-32-53)75-43-49(64(80)74-66(75)82)26-37-61(79)72-40-18-11-10-17-39-71-60(78)23-16-15-22-59-63-56(45-91-59)76(67(83)73-63)65(81)48-24-27-50(28-25-48)68(5,6)7/h12-14,20-21,24-37,43,46-47,56-59,62-63H,10-11,15-19,22-23,39-42,44-45H2,1-9H3,(H,71,78)(H,72,79)(H,73,83)(H,74,80,82)/t56-,57-,58+,59-,62+,63-,90?/m0/s1
Synonyms: 5'-Dimethoxytrityloxy-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Biotin-dT Amidite; Biotin-dT Phosphoramidite; (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-(3-((6-(5-((3aS,4S,6aR)-1-(4-(tert-butyl)benzoyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexyl)amino)-3-oxoprop-1-en-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMTr-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-dT-3'-CE-phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxythymidine-3'-O-[(2-cyanoethyl)-N,N-diisopropyl]-phosphoramidite; Biotin-dT
3'-O-DMT-N6-Benzoyl-Cytidine TNA 2'-CE phosphoramidite (BRP-02365)

3'-O-DMT-N6-Benzoyl-Cytidine TNA 2'-CE phosphoramidite

Description: TNA 2'-CE oligonucleotide synthesis necessitates 3'-O-DMT-N6-benzoyl-cytidine, and our TNA 2'-CE phosphoramidite is precisely engineered for just that purpose. Researchers within the biomedicine discipline rely heavily on our product due to their capacity to incorporate TNA monomers as they fabricate artificial nucleic acids for gene-based therapeutics and pharmacological advancement.
CAT: BRP-02365
CAS: 325683-96-3
Molecular Formula: C45H50N5O8P
Molecular Weight: 819.90
Purity: 98%
Size Price Stock Quantity
1 g $998 In stock
100 mg $398 In stock
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InChIKey: URCWUOWKRJMYKD-RBZSHJCZSA-N
SMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(COC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)OC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC
IUPAC Name: N-[1-[(2R,3R,4S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C45H50N5O8P/c1-31(2)50(32(3)4)59(56-29-13-27-46)58-41-39(30-55-43(41)49-28-26-40(48-44(49)52)47-42(51)33-14-9-7-10-15-33)57-45(34-16-11-8-12-17-34,35-18-22-37(53-5)23-19-35)36-20-24-38(54-6)25-21-36/h7-12,14-26,28,31-32,39,41,43H,13,29-30H2,1-6H3,(H,47,48,51,52)/t39-,41+,43+,59?/m0/s1
Synonyms: Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; DMTr-TNA C(Bz)-amidite; (2R,3R,4S)-2-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; TNA-C(Bz)-CE-Phosphoramidite; N-Benzoyl-1-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]cytosine; DMTr-TNA-C(Bz)-Phosphoramidite
3'-O-DMT-O6-DPC-N2-Acetyl-Guanosine TNA 2'-CE phosphoramidite (BRP-02367)

3'-O-DMT-O6-DPC-N2-Acetyl-Guanosine TNA 2'-CE phosphoramidite

Description: 3'-O-DMT-O6-DPC-N2-Acetyl-Guanosine TNA 2'-CE phosphoramidite is a highly complex chemical compound utilized in the biomedical industry to fabricate nucleic acid-based drugs that effectively combat a multitude of ailments, including but not limited to cancer, viral infections, and genetic disorders. The intricate nature of the molecule allows for the synthesis of oligonucleotides that specifically target variably expressed genes, culminating in an unparalleled approach towards achieving precision medication. Procuring this compound necessitates a specialized skill set and equipment, and can only be obtained from esteemed chemical outlets.
CAT: BRP-02367
CAS: 325683-97-4
Molecular Formula: C54H57N8O9P
Molecular Weight: 993.05
Purity: 98%
Size Price Stock Quantity
1 g $998 In stock
100 mg $398 In stock
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InChIKey: QGLNDUMJEPXLMP-DMYMLFOFSA-N
SMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(COC1N2C=NC3=C2N=C(N=C3OC(=O)N(C4=CC=CC=C4)C5=CC=CC=C5)NC(=O)C)OC(C6=CC=CC=C6)(C7=CC=C(C=C7)OC)C8=CC=C(C=C8)OC
IUPAC Name: [2-acetamido-9-[(2R,3R,4S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]聽N,N-diphenylcarbamate
InChI: InChI=1S/C54H57N8O9P/c1-36(2)62(37(3)4)72(68-33-17-32-55)71-48-46(70-54(39-18-11-8-12-19-39,40-24-28-44(65-6)29-25-40)41-26-30-45(66-7)31-27-41)34-67-51(48)60-35-56-47-49(60)58-52(57-38(5)63)59-50(47)69-53(64)61(42-20-13-9-14-21-42)43-22-15-10-16-23-43/h8-16,18-31,35-37,46,48,51H,17,33-34H2,1-7H3,(H,57,58,59,63)/t46-,48+,51+,72?/m0/s1
Synonyms: DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite; TNA-G(O-CONPh2)(N-Ac)CE-Phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[2-(acetylamino)-6-[[(diphenylamino)carbonyl]oxy]-9H-purin-9-yl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; 2-Acetamido-9-((2R,3R,4S)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl diphenylcarbamate
GalNAc-NAG-25 Phosphoramidite (BRP-02368)

GalNAc-NAG-25 Phosphoramidite

Description: GalNAc-NAG-25 Phosphoramidite is a modified phosphoramidite that incorporates a N-acetylgalactosamine (GalNAc) moiety linked to the NAG component, specifically designed for the synthesis of oligonucleotides. This compound enhances the stability and bioactivity of nucleic acids, particularly in applications involving targeted delivery and therapeutic interventions. Its unique structural features allow for improved interactions with cellular receptors, making GalNAc-NAG-25 Phosphoramidite valuable in the development of glyco-engineered therapeutics and in the field of glycobiology, where carbohydrate-based modifications play a crucial role in biological processes.
CAT: BRP-02368
CAS: 2130036-52-9
Molecular Formula: C88H145N10O43P
Molecular Weight: 2062.13
Purity: ≥95%
Appearance: White to light yellow powder
Size Price Stock Quantity
1 g $499 In stock
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Storage: Store at -20 °C
Boiling Point: 1590.2±65.0 °C at 760 mmHg
InChIKey: GTRPVVVEZDWBLA-ODUHJEIDSA-N
SMILES: O=C(C)O[C@@H]([C@H]1OC(C)=O)[C@H]([C@@H](O[C@@H]1COC(C)=O)OCCOCCNC(CC[C@@H](C(NCCOCCO[C@@H]([C@@H]([C@H]([C@H]2OC(C)=O)OC(C)=O)NC(C)=O)O[C@@H]2COC(C)=O)=O)NC(CC[C@@H](C(NCCOCCO[C@@H]3O[C@@H]([C@@H]([C@@H]([C@H]3NC(C)=O)OC(C)=O)OC(C)=O)COC(C)=O)=O)NC(CCOCCOCCOCCOCCOCCOCCOP(N(C(C)C)C(C)C)OCCC#N)=O)=O)=O)NC(C)=O
InChI: InChI=1S/C88H145N10O43P/c1-53(2)98(54(3)4)142(131-27-17-23-89)132-49-45-124-41-40-123-39-38-122-37-36-121-35-34-120-33-32-116-28-22-74(113)97-68(85(115)92-26-31-119-44-48-127-88-77(95-57(7)101)83(138-66(16)110)80(135-63(13)107)71(141-88)52-130-60(10)104)19-21-73(112)96-67(84(114)91-25-30-118-43-47-126-87-76(94-56(6)100)82(137-65(15)109)79(134-62(12)106)70(140-87)51-129-59(9)103)18-20-72(111)90-24-29-117-42-46-125-86-75(93-55(5)99)81(136-64(14)108)78(133-61(11)105)69(139-86)50-128-58(8)102/h53-54,67-71,75-83,86-88H,17-22,24-52H2,1-16H3,(H,90,111)(H,91,114)(H,92,115)(H,93,99)(H,94,100)(H,95,101)(H,96,112)(H,97,113)/t67-,68-,69+,70+,71+,75+,76+,77+,78-,79-,80-,81+,82+,83+,86+,87+,88+,142?/m0/s1
Synonyms: NAG-25; NAG 25; NAG25; GalNAc NAG-25 Phosphoramidite; N2-[23-[Bis(1-methylethyl)amino]-26-cyano-1-oxo-4,7,10,13,16,19,22,24-octaoxa-23-phosphahexacos-1-yl]-N-[2-[2-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]-L-γ-glutamyl-N,N2-bis[2-[2-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethyl]-L-glutamamide
3'-O-DMT-N6-Benzoyl-Adenosine TNA 2'-CE phosphoramidite (BRP-02380)

3'-O-DMT-N6-Benzoyl-Adenosine TNA 2'-CE phosphoramidite

Description: 3'-O-DMT-N6-Benzoyl-Adenosine TNA 2'-CE phosphoramidite is a modified nucleotide used in the synthesis of Threose Nucleic Acid (TNA) molecules for biomedical research. TNA is a promising alternative to DNA and RNA for gene and drug delivery due to its chemical stability and resistance to nuclease degradation. This specific phosphoramidite derivative incorporates a benzoyl-adenosine moiety, making it ideal for designing TNA-based drugs for the treatment of viral infections, inflammatory diseases, and cancer.
CAT: BRP-02380
CAS: 325683-93-0
Molecular Formula: C46H50N7O7P
Molecular Weight: 843.92
Purity: 98%
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1 g $998 In stock
100 mg $398 In stock
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InChIKey: QDGHMYBPKHSPSZ-BZWOVQDPSA-N
SMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(COC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)OC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
IUPAC Name: N-[9-[(2R,3R,4S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C46H50N7O7P/c1-31(2)53(32(3)4)61(58-27-13-26-47)60-41-39(28-57-45(41)52-30-50-40-42(48-29-49-43(40)52)51-44(54)33-14-9-7-10-15-33)59-46(34-16-11-8-12-17-34,35-18-22-37(55-5)23-19-35)36-20-24-38(56-6)25-21-36/h7-12,14-25,29-32,39,41,45H,13,27-28H2,1-6H3,(H,48,49,51,54)/t39-,41+,45+,61?/m0/s1
Synonyms: DMTr-TNA A(Bz)-amidite; TNA-A(Bz)-CE-Phosphoramidite; DMTr-TNA A(Bz)-Phosphoramidite; N-Benzoyl-9-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]-9H-purine-6-amine; 1-{2'-O-[(2-Cyanoethoxy)(diisopropyl amino)phosphino]-3'-O-[(4,4'-dimethoxytriphenyl)methyl]-a-L-threofuranosyl}-N6-benzoyladenine; (2R,3R,4S)-2-[6-(Benzoylamino)-9H-purin-9-yl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[6-(benzoylamino)-9H-purin-9-yl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2R,3R,4S)-2-[6-(benzoylamino)-9H-purin-9-yl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester
DMTr-LNA-C(Bz)-3-CED-phosphoramidite (BRP-00015)

DMTr-LNA-C(Bz)-3-CED-phosphoramidite

Description: DMTr-LNA-C(Bz)-3-CED-phosphoramidite is a purine nucleoside analog which has broad antitumor activity targeting indolent lymphoid malignancies.
CAT: BRP-00015
CAS: 206055-78-9
Molecular Formula: C47H52N5O9P
Molecular Weight: 861.93
Purity: 95%
Appearance: White solid
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InChIKey: SSGINSHBUWKRHC-XCHZTBEFSA-N
SMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C2C(OC1(CO2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)N6C=CC(=NC6=O)NC(=O)C7=CC=CC=C7
IUPAC Name: N-[1-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C47H52N5O9P/c1-32(2)52(33(3)4)62(59-29-13-27-48)61-42-41-44(51-28-26-40(50-45(51)54)49-43(53)34-14-9-7-10-15-34)60-46(42,30-57-41)31-58-47(35-16-11-8-12-17-35,36-18-22-38(55-5)23-19-36)37-20-24-39(56-6)25-21-37/h7-12,14-26,28,32-33,41-42,44H,13,29-31H2,1-6H3,(H,49,50,53,54)/t41-,42+,44-,46-,62?/m1/s1
Synonyms: LNA-C(Bz)-CE Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-LNA-cytidine-3'-cyanoethyl phosphoramidite; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O,4'-C-methylene-cytidine 3'-O-[(2-cyanoethyl) (N,N-diisopropyl)]-phosphorramidite; 5'-O-DMTr-2'-O-4'-C-Locked-C(Bz) Phosphoramidite; DMT-locC(bz)Amidite; DMT-locC(bz) phosphoramidite; LNA-C(Bz)-3-CED-phosphoramidite; Bz-C-LA-CE Phosphoramidite
DMTr-LNA-G(iBu)-3'-CED-phosphoramidite (BRP-00016)

DMTr-LNA-G(iBu)-3'-CED-phosphoramidite

Description: DMTr-LNA-G(iBu)-3'-CED-phosphoramidite is a phosphoramidite used in the biomedical industry for the synthesis of modified nucleic acids. It contains DMTr-protected LNA-G(iBu)-3'-CED, which enables efficient and stable incorporation of modified bases during DNA/RNA synthesis.
CAT: BRP-00016
CAS: 206055-77-8
Molecular Formula: C45H54N7O9P
Molecular Weight: 867.94
Purity: ≥98% by HPLC
Appearance: Off-white to yellow powder
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InChIKey: UUBFSNDSLDOIDQ-NIQOLRRHSA-N
SMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C4C(C(O3)(CO4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C45H54N7O9P/c1-28(2)40(53)49-43-48-39-36(41(54)50-43)47-27-51(39)42-37-38(61-62(59-24-12-23-46)52(29(3)4)30(5)6)44(60-42,25-57-37)26-58-45(31-13-10-9-11-14-31,32-15-19-34(55-7)20-16-32)33-17-21-35(56-8)22-18-33/h9-11,13-22,27-30,37-38,42H,12,24-26H2,1-8H3,(H2,48,49,50,53,54)/t37-,38+,42-,44-,62?/m1/s1
Synonyms: N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-LNA-guanosine-3'-cyanoethyl phosphoramidite; LNA-G(ibu) phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O,4'-C-methyleneguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; LNA-G(iBu)-CE Phosphoramidite; DMTr-2'-O-4'-C-Locked-rG(iBu)-3'-CE-Phosphoramidite; DMT-2'-O-4'-C-Locked-G(iBu)-CE; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-Guanosine-3'-cyanoethyl Phosphoramidite; N2-iBu-2'-O-4'-C-Locked-Gr-CE-Phosphoramidite
5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite (BRP-00128)

5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite

Description: 5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite is a phosphoramidite derivative used in the synthesis of modified oligonucleotides for biomedical research. It enables the incorporation of 2'-O-methyl-pseudouridine modifications into RNA sequences, enhancing stability and specific RNA-protein interactions.
CAT: BRP-00128
CAS: 199737-09-2
Molecular Formula: C40H49N4O9P
Molecular Weight: 760.81
Purity: ≥95% by HPLC
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InChIKey: QRORKJSFBIFPIM-ALEZOLFBSA-N
SMILES: N#CCCOP(OC1C(OC(C2=CNC(=O)NC2=O)C1OC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C40H49N4O9P/c1-26(2)44(27(3)4)54(51-23-11-22-41)53-36-34(52-35(37(36)49-7)33-24-42-39(46)43-38(33)45)25-50-40(28-12-9-8-10-13-28,29-14-18-31(47-5)19-15-29)30-16-20-32(48-6)21-17-30/h8-10,12-21,24,26-27,34-37H,11,23,25H2,1-7H3,(H2,42,43,45,46)/t34-,35+,36-,37+,54?/m1/s1
Synonyms: 2'-O-Methyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; pseudoUridine (with 5'-DMT, 3'-phosphoramidite, and 2'-OMe); 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione
5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite (BRP-00130)

5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite

Description: It is a modified ribonucleoside analogue suitable for incorporation into small interfering RNA (siRNA) to enhance RNA stability in biological applications such as gene silencing.
CAT: BRP-00130
CAS: 875302-45-7
Molecular Formula: C46H63N4O9PSi
Molecular Weight: 875.07
Purity: ≥98%
Appearance: White to off-white powder
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InChIKey: ZDZLHJPETUXZJT-NSASEYFNSA-N
SMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)C2=CN(C(=O)NC2=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
IUPAC Name: (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C46H63N4O9PSi/c1-31(2)50(32(3)4)60(56-28-16-27-47)58-41-39(57-40(38-29-49(8)44(52)48-43(38)51)42(41)59-61(11,12)45(5,6)7)30-55-46(33-17-14-13-15-18-33,34-19-23-36(53-9)24-20-34)35-21-25-37(54-10)26-22-35/h13-15,17-26,29,31-32,39-42H,16,28,30H2,1-12H3,(H,48,51,52)/t39-,40+,41-,42+,60?/m1/s1
Synonyms: 5'-Dimethoxytrityl-1-methyl-pseudouridine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5-​[5-​O-​[bis(4-​methoxyphenyl)​phenylmethyl]​-​3-​O-​[[bis(1-methylethyl)​amino]​(2-​cyanoethoxy)​phosphino]​-​2-​O-​[(1,​1-​dimethylethyl)​dimethylsilyl]​-​β-​D-​ribofuranosyl]​-​1-​methyl-2,​4(1H,​3H)​-​pyrimidinedione; 2'-O-TBDMS-N1-Me-Pseudouridine CEP; 5'-O-DMTr-2'-O-TBDMS-N1-methylpseudouridine 3'-(cyanoethyl-N,N-diisopropyl)phosphoramidite; 5'-O-DMT-2'-O-TBDMS-N1-Me-pU Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-N1-methyl-Pseudouridine-3'-cyanoethyl Phosphoramidite
UNA-A(Bz)-CE Phosphoramidite (BRP-00132)

UNA-A(Bz)-CE Phosphoramidite

Description: UNA-A(Bz)-CE Phosphoramidite is an advanced biomedical compound used for the research of cancer, including breast and lung cancer. It acts by targeting specific cellular pathways involved in cancer progression, inhibiting tumor growth and promoting cell death.
CAT: BRP-00132
CAS: 1120329-52-3
Molecular Formula: C54H58N7O9P
Molecular Weight: 980.06
Purity: ≥98% by HPLC
Appearance: White to off-white powder
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InChIKey: DETQAICZNNZAEM-OWWCMFKUSA-N
SMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)OC(COC(=O)C4=CC=CC=C4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7
IUPAC Name: [(2R)-2-(6-benzamidopurin-9-yl)-2-[(2R)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]oxyethyl] benzoate
InChI: InChI=1S/C54H58N7O9P/c1-38(2)61(39(3)4)71(68-32-16-31-55)69-34-47(33-67-54(42-21-14-9-15-22-42,43-23-27-45(64-5)28-24-43)44-25-29-46(65-6)30-26-44)70-48(35-66-53(63)41-19-12-8-13-20-41)60-37-58-49-50(56-36-57-51(49)60)59-52(62)40-17-10-7-11-18-40/h7-15,17-30,36-39,47-48H,16,32-35H2,1-6H3,(H,56,57,59,62)/t47-,48-,71?/m1/s1
Synonyms: N6-Benzoyl-(5'-(4,4'-dimethoxytrityl)-2'-benzoyl-2',3'-seco-adenosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)] phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2R)-2-[(1R)-1-[6-(benzoylamino)-9H-purin-9-yl]-2-(benzoyloxy)ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester; (2R)-2-[(1R)-1-[6-(Benzoylamino)-9H-purin-9-yl]-2-(benzoyloxy)ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite
UNA-G(iBu)-CE Phosphoramidite (BRP-00133)

UNA-G(iBu)-CE Phosphoramidite

Description: UNA-G(iBu)-CE Phosphoramidite is a uniquely intricate compound possessing potential applications in the realm of cancer therapeutics. Possessing potent antineoplastic capabilities, it demonstrates high efficacy in the research of obstruction in malignant cellular proliferation.
CAT: BRP-00133
CAS: 1120329-61-4
Molecular Formula: C51H60N7O10P
Molecular Weight: 962.04
Purity: ≥98% by HPLC
Appearance: White to off-white powder
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InChIKey: PCZJDFIZVYBABW-WESQYFQMSA-N
SMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C(COC(=O)C3=CC=CC=C3)OC(COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)COP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: [(2R)-2-[(2R)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]oxy-2-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]ethyl] benzoate
InChI: InChI=1S/C51H60N7O10P/c1-34(2)47(59)55-50-54-46-45(48(60)56-50)53-33-57(46)44(32-64-49(61)37-16-11-9-12-17-37)68-43(31-67-69(66-29-15-28-52)58(35(3)4)36(5)6)30-65-51(38-18-13-10-14-19-38,39-20-24-41(62-7)25-21-39)40-22-26-42(63-8)27-23-40/h9-14,16-27,33-36,43-44H,15,29-32H2,1-8H3,(H2,54,55,56,59,60)/t43-,44-,69?/m1/s1
Synonyms: N2-Isobutyryl-(5'-(4,4'-dimethoxytrityl)-2'-benzoyl-2',3'-seco-guanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)] phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2R)-2-[(1R)-2-(benzoyloxy)-1-[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester; (2R)-2-[(1R)-2-(Benzoyloxy)-1-[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite
Yakima Yellow® Phosphoramidite (BRP-00218)

Yakima Yellow® Phosphoramidite

Description: Yakima Yellow® Phosphoramidite is a fluorescent phosphoramidite dye for 5’-end DNA labeling. It emits bright yellow fluorescence with excellent signal-to-noise performance.
CAT: BRP-00218
CAS: 502485-39-4
Molecular Formula: C49H60Cl4N3O10P
Molecular Weight: 1023.81
Appearance: Off-white solid
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InChIKey: POEPDWFKAYRZJK-UHFFFAOYSA-N
SMILES: CC1=C2C(=CC(=C1OC(=O)C(C)(C)C)Cl)C3(C4=CC(=C(C=C4C(=O)O3)Cl)Cl)C5=C(O2)C(=C(C(=C5)CCC(=O)NCCCCCCOP(N(C(C)C)C(C)C)OCCC#N)OC(=O)C(C)(C)C)Cl
IUPAC Name: [2',5,5',6-tetrachloro-7'-[3-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylamino]-3-oxopropyl]-6'-(2,2-dimethylpropanoyloxy)-4'-methyl-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C49H60Cl4N3O10P/c1-27(2)56(28(3)4)67(62-22-16-19-54)61-21-15-13-12-14-20-55-38(57)18-17-30-23-33-43(39(53)42(30)65-46(60)48(9,10)11)63-40-29(5)41(64-45(59)47(6,7)8)37(52)26-34(40)49(33)32-25-36(51)35(50)24-31(32)44(58)66-49/h23-28H,12-18,20-22H2,1-11H3,(H,55,57)
Synonyms: Y-Yellow Phosphoramidite; Yakima Yellow; 3-(5,6,4',7'-tetrachloro-5'-methyl-3',6'-dipivaloylfluorescein-2-yl)-propanamidohexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 1,1'-[2'-[12-[Bis(1-methylethyl)amino]-15-cyano-3-oxo-11,13-dioxa-4-aza-12-phosphapentadec-1-yl]-4',5,6,7'-tetrachloro-5'-methyl-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] bis(2,2-dimethylpropanoate); Propanoic acid, 2,2-dimethyl-, 2'-[3-[[6-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]hexyl]amino]-3-oxopropyl]-4',5,6,7'-tetrachloro-5'-methyl-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; Epoch Yakima Yellow Phosphoramidite; Yakima Yellow Amidite; Yakima Yellow Phosphoramidite
DyLight 3 CEP (BRP-00220)

DyLight 3 CEP

Description: DyLight 3 CEP is a fluorescent dye used for oligonucleotide labeling.
CAT: BRP-00220
CAS: 182873-76-3
Molecular Formula: C58H70CIN4O4P
Molecular Weight: 953.64
Purity: ≥90%
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Storage: Store at -20°C
InChIKey: DQXAVRZQYYKELZ-UHFFFAOYSA-M
SMILES: CC(C)N(C(C)C)P(OCCC[N+]1=C(C(C2=CC=CC=C21)(C)C)C=CC=C3C(C4=CC=CC=C4N3CCCOC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=C(C=C7)OC)(C)C)OCCC#N.[Cl-]
IUPAC Name: 3-[[di(propan-2-yl)amino]-[3-[2-[3-[1-[3-[(4-methoxyphenyl)-diphenylmethoxy]propyl]-3,3-dimethylindol-2-ylidene]prop-1-enyl]-3,3-dimethylindol-1-ium-1-yl]propoxy]phosphanyl]oxypropanenitrile;chloride
InChI: InChI=1S/C58H70N4O4P.ClH/c1-44(2)62(45(3)4)67(65-42-21-38-59)66-43-23-40-61-53-31-19-17-29-51(53)57(7,8)55(61)33-20-32-54-56(5,6)50-28-16-18-30-52(50)60(54)39-22-41-64-58(46-24-12-10-13-25-46,47-26-14-11-15-27-47)48-34-36-49(63-9)37-35-48;/h10-20,24-37,44-45H,21-23,39-43H2,1-9H3;1H/q+1;/p-1
Synonyms: Cy3 MMTr CE Phosphoramidite; 1-[3-(4-monomethoxytrityloxy)propyl]-1'-[3-[(2-cyanoethyl)-(N,N-diisopropyl)phosphoramidityl]propyl]-3,3,3',3'-tetramethylindocarbocyanine chloride; Cyanine 3 Phosphoramidite
Related CAS: 718594-66-2 (free base)
Eclipse® Quencher Phosphoramidite (BRP-00227)

Eclipse® Quencher Phosphoramidite

Description: Eclipse® Quencher Phosphoramidite is a paramount constituent employed in the fabrication of oligonucleotides, emerges as a pivotal ensemble. Its functions lie in its ability to dampen the fluorescence signal within nucleotide probes, consequently facilitating meticulous identification of distinctive DNA or RNA sequences. It substantiates its worth by contributing to the proficiency of diagnostic assays and molecular biology research, consequently augmenting the detection and scrutiny of assorted maladies and genetic irregularities.
CAT: BRP-00227
CAS: 916753-64-5
Molecular Formula: C52H61CIN7O8P
Molecular Weight: 978.51
Appearance: Black solid
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Storage: Store at -20°C
Boiling Point: 962.2±65.0 °C (Predicted)
InChIKey: CXNVOZCFZYENEQ-SOWLJRCBNA-N
SMILES: N#CCCOP(OC1CN(C(=O)CCCN(C2=CC=C(N=NC3=CC=C(C=C3Cl)N(=O)=O)C=C2)C)C(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C1)N(C(C)C)C(C)C
IUPAC Name: rel-(3R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-1-(4-((4-((2-chloro-4-nitrophenyl)diazenyl)phenyl)(methyl)amino)butanoyl)pyrrolidin-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1/C52H61ClN7O8P/c1-37(2)59(38(3)4)69(67-32-12-30-54)68-48-33-45(36-66-52(39-13-9-8-10-14-39,40-16-25-46(64-6)26-17-40)41-18-27-47(65-7)28-19-41)58(35-48)51(61)15-11-31-57(5)43-22-20-42(21-23-43)55-56-50-29-24-44(60(62)63)34-49(50)53/h8-10,13-14,16-29,34,37-38,45,48H,11-12,15,31-33,35-36H2,1-7H3/t45-,48+,69?/s2
Synonyms: EclipseQ Phosphoramidite; Eclipse Quencher Phosphoramidite; 4-N-methyl-N-(4'-nitro-2'-chloroazobenzen-4-yl)-aminobutanamido-1-(2-O-dimethoxytrityloxymethyl)-pyrrolidin-4-yl-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramdite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (3R,5S)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[4-[[4-[2-(2-chloro-4-nitrophenyl)diazenyl]phenyl]methylamino]-1-oxobutyl]-3-pyrrolidinyl 2-cyanoethyl ester, rel-; rel-(3R,5S)-5-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[4-[[4-[2-(2-chloro-4-nitrophenyl)diazenyl]phenyl]methylamino]-1-oxobutyl]-3-pyrrolidinyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; 5'-Eclipse Amidite
5'-Amino Modifier C3-TFA CE Phosphoramidite (BRP-00229)

5'-Amino Modifier C3-TFA CE Phosphoramidite

Description: 5'-Amino Modifier C3-TFA CE Phosphoramidite is a valuable product used in the biomedical industry for the synthesis of modified nucleic acids. This phosphoramidite reagent allows for the introduction of an amino modifier group at the 5' position of nucleosides, enabling the creation of modified oligonucleotides with enhanced properties. It finds applications in various fields such as drug discovery, gene synthesis, and molecular diagnostics.
CAT: BRP-00229
CAS: 853955-89-2
Molecular Formula: C14H25F3N3O3P
Molecular Weight: 371.34
Appearance: Colorless Oil
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Storage: Store at -20 °C
Boiling Point: 391.4±42.0 °C at 760 mmHg
InChIKey: AOAXRHUQUZSDAX-UHFFFAOYSA-N
SMILES: CC(C)N(C(C)C)P(OCCCNC(=O)C(F)(F)F)OCCC#N
IUPAC Name: N-[3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropyl]-2,2,2-trifluoroacetamide
InChI: InChI=1S/C14H25F3N3O3P/c1-11(2)20(12(3)4)24(22-9-5-7-18)23-10-6-8-19-13(21)14(15,16)17/h11-12H,5-6,8-10H2,1-4H3,(H,19,21)
Synonyms: 5'-Amino Modifier C3 TFA CE Phosphoramidite; 5'-Amino-modifier-C 3-tfa cep; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 3-[(trifluoroacetyl)amino]propyl ester; 2-Cyanoethyl 3-[(trifluoroacetyl)amino]propyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 3-[(trifluoroacetyl)amino]propyl ester; 5'-Amino-Modifier C3-TFA
5'-BHQ-1 Phosphoramidite (BRP-00234)

5'-BHQ-1 Phosphoramidite

Description: 5'-BHQ-1 Phosphoramidite, an indispensable reagent, is widely employed in synthesizing oligonucleotides with numerous biomedical potentialities. A notable function is creating luminous probes for detecting nucleic acid sequences in vivo and in vitro. Moreover, it has crucially contributed to the progress in crafting diagnostic devices for malignant neoplasms, viral infections and innate deficiencies.
CAT: BRP-00234
CAS: 1430816-77-5
Molecular Formula: C34H45N8O5P
Molecular Weight: 676.75
Purity: ≥98% by HPLC
Appearance: Dark red solid
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Storage: Store at -20°C
InChIKey: PYSPQPFQYWCYDV-UHFFFAOYSA-N
SMILES: CCN(CCOP(N(C(C)C)C(C)C)OCCC#N)C1=CC=C(C=C1)N=NC2=C(C=C(C(=C2)C)N=NC3=C(C=C(C=C3)C)[N+](=O)[O-])OC
IUPAC Name: 3-[[di(propan-2-yl)amino]-[2-[N-ethyl-4-[[2-methoxy-5-methyl-4-[(4-methyl-2-nitrophenyl)diazenyl]phenyl]diazenyl]anilino]ethoxy]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C34H45N8O5P/c1-9-40(18-20-47-48(46-19-10-17-35)41(24(2)3)25(4)5)29-14-12-28(13-15-29)36-39-32-22-27(7)31(23-34(32)45-8)38-37-30-16-11-26(6)21-33(30)42(43)44/h11-16,21-25H,9-10,18-20H2,1-8H3
Synonyms: 4'-(2-Nitro-4-toluyldiazo)-2'-methoxy-5'-methyl-azobenzene-4''-(N-ethyl)-N-ethyl-2-cyanoethyl-(N,N-diisopropyl)-phosphoramidite; 5'-HDQ-1 Phosphoramidite; BHQ-1-Amidite; BHQ-1 Amidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 2-[ethyl[4-[2-[2-methoxy-5-methyl-4-[2-(4-methyl-2-nitrophenyl)diazenyl]phenyl]diazenyl]phenyl]amino]ethyl ester; 2-Cyanoethyl 2-[ethyl[4-[2-[2-methoxy-5-methyl-4-[2-(4-methyl-2-nitrophenyl)diazenyl]phenyl]diazenyl]phenyl]amino]ethyl N,N-bis(1-methylethyl)phosphoramidite; DusQ1 amidite, 5'-terminal

Frequently Asked Questions (FAQ)

What are phosphoramidites used for?

Phosphoramidites are activated monomers used in solid-phase DNA and RNA oligonucleotide synthesis.

RNA phosphoramidites include additional 2′-hydroxyl protecting groups, making them more sensitive to moisture and handling conditions.

Moisture can cause premature hydrolysis of phosphoramidites, reducing coupling efficiency and synthesis yield.

Yes, high-quality phosphoramidites are essential for achieving good yields in long and complex oligonucleotide sequences.

Modified and specialty phosphoramidites are commonly used to introduce functional groups or labels into oligonucleotides.

* Only for research. Not suitable for any diagnostic or therapeutic use.

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