What are phosphoramidites used for?

Phosphoramidites are activated monomers used in solid-phase DNA and RNA oligonucleotide synthesis.

What is the difference between DNA and RNA phosphoramidites?

RNA phosphoramidites include additional 2′-hydroxyl protecting groups, making them more sensitive to moisture and handling conditions.

Why is moisture control important for phosphoramidites?

Moisture can cause premature hydrolysis of phosphoramidites, reducing coupling efficiency and synthesis yield.

Can phosphoramidites be used for long oligonucleotide synthesis?

Yes, high-quality phosphoramidites are essential for achieving good yields in long and complex oligonucleotide sequences.

Are modified phosphoramidites available for custom oligos?

Modified and specialty phosphoramidites are commonly used to introduce functional groups or labels into oligonucleotides.

Phosphoramidites - RNA / BOC Sciences

5'-O-DMT-2'-O-TBDMS-N4-Acetyl-L-Cytidine 3'-CE phosphoramidite (BRP-02181)

Description: 5'-O-DMT-2'-O-TBDMS-N4-Acetyl-L-Cytidine 3'-CE phosphoramidite, a remarkable substance within the biomedical field, holds immense significance. Its application in the synthesis of altered oligonucleotides for therapeutic intentions is widespread. Through the specific manipulation and addressing of genetic material, particularly RNA, it exhibits a pivotal role in combating diverse ailments. Boasting an exceptional composition, this product possesses the power to revolutionize precision medicine and propel the progression of targeted therapies.

CAT: BRP-02181

CAS: 237060-94-5

Molecular Formula: C47H64N5O9PSi

Molecular Weight: 902.11

Purity: ≥98% by HPLC

Appearance: White to Off-white Powder

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Storage: Store at -20 °C

InChIKey: QKWKXYVKGFKODW-ZYRNLWDWSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: N-[1-[(2S,3S,4S,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C47H64N5O9PSi/c1-32(2)52(33(3)4)62(58-30-16-28-48)60-42-40(59-44(43(42)61-63(11,12)46(6,7)8)51-29-27-41(49-34(5)53)50-45(51)54)31-57-47(35-17-14-13-15-18-35,36-19-23-38(55-9)24-20-36)37-21-25-39(56-10)26-22-37/h13-15,17-27,29,32-33,40,42-44H,16,30-31H2,1-12H3,(H,49,50,53,54)/t40-,42-,43-,44-,62?/m0/s1

Synonyms: Acetamide, N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-; DMT-2'-O-TBDMS-L-rC(Ac) Phosphoramidite

Related CAS: 121058-88-6 (R-isomer)

N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite (BRP-02182)

Description: N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite is used to incorporate 2'-O-methoxyethyl-modified A into oligonucleotide phosphoramidites, which is useful for antisense RNA. The 2'-MOE backbone provides stronger duplex stability, significant nuclease resistance and relatively low toxicity.

CAT: BRP-02182

CAS: 251647-53-7

Molecular Formula: C50H58N7O9P

Molecular Weight: 932.01

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at -20 °C

InChIKey: VPBYBQBHLYRLHG-HDMAWCRFSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCOC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-(2-methoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C50H58N7O9P/c1-34(2)57(35(3)4)67(64-28-14-27-51)66-44-42(31-63-50(37-17-12-9-13-18-37,38-19-23-40(60-6)24-20-38)39-21-25-41(61-7)26-22-39)65-49(45(44)62-30-29-59-5)56-33-54-43-46(52-32-53-47(43)56)55-48(58)36-15-10-8-11-16-36/h8-13,15-26,32-35,42,44-45,49H,14,28-31H2,1-7H3,(H,52,53,55,58)/t42-,44-,45-,49-,67?/m1/s1

Synonyms: N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)adenosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite; N6-Bz-5'-O-DMTr-2'-O-(2-methoxyethyl)-adenosine-3'-CED-phosphoramidite; 2'-O-MOE-A(Bz)-3'-phosphoramidite; N6-Benzoyl-5'-O-DMT-2'-O-MOE-adenosine 3'-CE phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-(2-methoxyethyl)adenosine; DMT-2'-O-MOE-A(Bz)-CE-Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl Phosphoramidite

5'-O-DMT-2'-O-tert-Butyldimethylsilyl-Inosine 3'-CE phosphoramidite (BRP-02183)

Description: Antiviral and anticancer drug for cells infected with influenza A virus, herpes simplex virus type 2, and human lymphocytic leukemia cells.

CAT: BRP-02183

CAS: 261518-12-1

Molecular Formula: C46H61N6O8PSi

Molecular Weight: 885.07

Purity: ≥97% by HPLC

Appearance: White to Off-white Powder

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2 g	$499	In stock

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Storage: Store at RT

Boiling Point: 866.8±75.0°C at 760 mmHg

InChIKey: ZUFMOUFQBYZIHB-JFOZTMRSSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=NC3=C2N=CNC3=O)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

IUPAC Name: 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-(6-oxo-1H-purin-9-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C46H61N6O8PSi/c1-31(2)52(32(3)4)61(57-27-15-26-47)59-40-38(58-44(41(40)60-62(10,11)45(5,6)7)51-30-50-39-42(51)48-29-49-43(39)53)28-56-46(33-16-13-12-14-17-33,34-18-22-36(54-8)23-19-34)35-20-24-37(55-9)25-21-35/h12-14,16-25,29-32,38,40-41,44H,15,27-28H2,1-11H3,(H,48,49,53)/t38-,40-,41-,44-,61?/m1/s1

Synonyms: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-inosine 3'-CE phosphoramidite; 2'-O-(tert-Butyldimethylsilyl)-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)inosine; Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]inosine; DMT-2'-O-TBDMS-I-CE-Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-inosine-3'-cyanoethyl Phosphoramidite

N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE-phosphoramidite (BRP-02184)

Description: N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-CE-phosphoramidite is an antiviral agent that inhibits the replication of DNA.

CAT: BRP-02184

CAS: 329187-86-2

Molecular Formula: C47H51FN7O7P

Molecular Weight: 875.92

Purity: ≥95%

Appearance: White to off-white powder

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Storage: Store at -20 °C

Boiling Point: 905.8±75.0°C at 760 mmHg

InChIKey: VCCMVPDSLHFCBB-SAHKUVNLSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1F)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

IUPAC Name: N-[9-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-fluorooxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C47H51FN7O7P/c1-31(2)55(32(3)4)63(60-27-13-26-49)62-42-39(61-46(40(42)48)54-30-52-41-43(50-29-51-44(41)54)53-45(56)33-14-9-7-10-15-33)28-59-47(34-16-11-8-12-17-34,35-18-22-37(57-5)23-19-35)36-20-24-38(58-6)25-21-36/h7-12,14-25,29-32,39-40,42,46H,13,27-28H2,1-6H3,(H,50,51,53,56)/t39-,40+,42-,46-,63?/m1/s1

Synonyms: N6-Bz-5'-O-DMTr-2'-fluoro-2'-deoxyarabinoadenosine-3'-CEN-phosphoramidite; 2'-Fluoro-2'-deoxy-ara-A(Bz)-3'-phosphoramidite; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxyarabinoadenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 5'-O-DMT-N6-Benzoyl-2'-fluoro-2'-arabinofuranosyl-2'-deoxyadenosine 3'-CE phosphoramidite; 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-6-{[hydroxy(phenyl)methylene]amino}-9H-purine; 2'-F-A(Bz)-ANA-CE-Phosphoramidite; 5'-Dimethoxytrityl-N6-benzoyl-2'-deoxy-2'-fluoroarabinoadenosine 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2'-FANA-A(Bz) Phosphoramidite

5'-O-DMT-2'-O-TBDMS-N2-isobutyryl-L-Guanosine 3'-CE phosphoramidite (BRP-02186)

Description: 5'-O-DMT-2'-O-TBDMS-N2-isobutyryl-L-Guanosine 3'-CE phosphoramidite, a sophisticated compound integral to the production of custom oligonucleotides, showcases remarkable versatility. It serves as a phosphoramidite foundation during solid-phase DNA synthesis, facilitating the integration of guanosine modifications. By harnessing this product, nucleic acid researchers can probe gene expression or delve into the impact of guanosine alterations on ailments such as cancer.

CAT: BRP-02186

CAS: 679809-76-8

Molecular Formula: C50H68N7O9PSi

Molecular Weight: 970.19

Purity: ≥98% by HPLC

Appearance: White, off-white to faint yellow powder

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Storage: Store at -20 °C

InChIKey: PGJKESPHANLWME-ZEXYNXKFSA-N

CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1O[Si](C)(C)C(C)(C)C)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C

IUPAC Name: N-[9-[(2S,3S,4S,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C50H68N7O9PSi/c1-32(2)45(58)54-48-53-44-41(46(59)55-48)52-31-56(44)47-43(66-68(12,13)49(7,8)9)42(65-67(63-29-17-28-51)57(33(3)4)34(5)6)40(64-47)30-62-50(35-18-15-14-16-19-35,36-20-24-38(60-10)25-21-36)37-22-26-39(61-11)27-23-37/h14-16,18-27,31-34,40,42-43,47H,17,29-30H2,1-13H3,(H2,53,54,55,58,59)/t40-,42-,43-,47-,67?/m0/s1

Synonyms: DMT-2'-O-TBDMS-L-rG(ibu) Phosphoramidite; N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropanamide; L-rG(ibu) Phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-G(iBu)-3'-CE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-guanosine-3'-cyanoethyl Phosphoramidite

Related CAS: 147201-04-5 (R-isomer)

5'-O-DMT-N2-isobutyryl-2'-O-methoxyethylguanosine 3'-CE phosphoramidite (BRP-02192)

Description: 5'-O-DMT-N2-isobutyryl-2'-O-methoxyethylguanosine 3'-CE phosphoramidite is used to incorporate 2'-O-methoxyethyl-modified G into oligonucleotides, which is useful for antisense RNA.

CAT: BRP-02192

CAS: 251647-55-9

Molecular Formula: C47H60N7O10P

Molecular Weight: 913.99

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at 2-8 °C, protect from light

InChIKey: LADCDGNEBIQAAU-SBCRAQIVSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCOC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C47H60N7O10P/c1-30(2)43(55)51-46-50-42-39(44(56)52-46)49-29-53(42)45-41(60-27-26-57-7)40(64-65(62-25-13-24-48)54(31(3)4)32(5)6)38(63-45)28-61-47(33-14-11-10-12-15-33,34-16-20-36(58-8)21-17-34)35-18-22-37(59-9)23-19-35/h10-12,14-23,29-32,38,40-41,45H,13,25-28H2,1-9H3,(H2,50,51,52,55,56)/t38-,40-,41-,45-,65?/m1/s1

Synonyms: 5'-O-DMTr-N2-iBu-2'-O-MOE-guanosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-iso-butyroyl-2'-O-(2-methoxyethyl)guanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; 2'-MOE-G(iBu)-3'-phosphoramidite; DMT-2M-O-Me-rG(ib) amidite; N2-isobutyryl-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite; N-Isobutyryl-2'-O-(2-methoxyethyl)-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)guanosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-(2-methoxyethyl)guanosine

N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite (BRP-02194)

Description: N-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It features a benzoyl group protecting the adenine base, a 5'-dimethoxytrityl (DMT) group for 5'-hydroxyl protection, a 2'-O-methyl group to enhance stability, and a cyanoethyl (CE) group on the 3'-phosphoramidite for protection during synthesis. These modifications facilitate the incorporation of modified adenosine into oligonucleotides, improving their stability and performance in various applications such as genetic research and therapeutic development.

CAT: BRP-02194

CAS: 110782-31-5

Molecular Formula: C48H54N7O8P

Molecular Weight: 887.96

Purity: ≥98% by HPLC

Appearance: White to Off-white Solid

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Storage: Store at -20 °C, under inert atmosphere

Melting Point: 93-95 °C

InChIKey: AZCGOTUYEPXHMJ-PSVHYZMASA-N

Solubility: Soluble in Acetonitrile (Sparingly), DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OC)N2C=NC3=C2N=CN=C3NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C48H54N7O8P/c1-32(2)55(33(3)4)64(61-28-14-27-49)63-42-40(62-47(43(42)59-7)54-31-52-41-44(50-30-51-45(41)54)53-46(56)34-15-10-8-11-16-34)29-60-48(35-17-12-9-13-18-35,36-19-23-38(57-5)24-20-36)37-21-25-39(58-6)26-22-37/h8-13,15-26,30-33,40,42-43,47H,14,28-29H2,1-7H3,(H,50,51,53,56)/t40-,42-,43-,47-,64?/m1/s1

Synonyms: N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite; Dmt-2'-O-me-ra(bz) amidite; 2'-O-Methyl-rA(N-Bz)phosphoramidite; DMT-2'O-Methyl-rA(bz) Phosphoramidite; 5'-O-DMT-2'-O-Me-A(bz) phosphoramidite; 2'-OMe-Bz-A-CE-Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-Adenosine-3'-CE-Phosphoramidite

5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite (BRP-02195)

Description: 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite is a phosphoramidite compound used to introduce 2-fluoro-modified nucleotides into oligonucleotides.

CAT: BRP-02195

CAS: 159414-99-0

Molecular Formula: C41H49FN5O8P

Molecular Weight: 789.83

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at -20 °C

InChIKey: CNFKJHKDSRXNFL-UTXREMQHSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1F)N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-fluorooxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C41H49FN5O8P/c1-27(2)47(28(3)4)56(53-25-11-23-43)55-38-35(54-39(37(38)42)46-24-22-36(44-29(5)48)45-40(46)49)26-52-41(30-12-9-8-10-13-30,31-14-18-33(50-6)19-15-31)32-16-20-34(51-7)21-17-32/h8-10,12-22,24,27-28,35,37-39H,11,25-26H2,1-7H3,(H,44,45,48,49)/t35-,37-,38-,39-,56?/m1/s1

Synonyms: N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite; 2'-F-Ac-dC CE phosphoramide; 2'-F-Ac-dC Phosphoramidite; DMT-2'-F-dC(Ac) amidite; DMT-2'Fluoro-dC(Ac) Phosphoramidite; DMT-2'-F-dC(Ac)-CE Phosphoramidite; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxycytidine-3'-CE-Phosphoramidite; 2'-Fluoro-2'-deoxy Cytidine (n-ac) CED Phosphoramidite; 5'-O-DMT-2'-F-Acetyl-Deoxycytidine-CE Phosphoramidite; 5'-O-DMT-2'-F-dC(Ac) 3'-CE phosphoramidite

dSpacer-CEP (BRP-02204)

Description: dSpacer is used to introduce stable abasic sites in oligonucleotides.

CAT: BRP-02204

CAS: 129821-76-7

Molecular Formula: C35H45N2O6P

Molecular Weight: 620.71

Purity: ≥95%

Appearance: Colorless to light yellow oily matter

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100 mg	$329	In stock
1 g	$893	In stock

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Storage: Store at -20 °C

Boiling Point: 658.6±55.0 °C at 760 mmHg

Shipping: Dry ice

InChIKey: XZGSDLJMHWJDHL-JUWSMZLESA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CCOC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC

IUPAC Name: 3-[[(2R,3S)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C35H45N2O6P/c1-26(2)37(27(3)4)44(42-23-10-22-36)43-33-21-24-40-34(33)25-41-35(28-11-8-7-9-12-28,29-13-17-31(38-5)18-14-29)30-15-19-32(39-6)20-16-30/h7-9,11-20,26-27,33-34H,10,21,23-25H2,1-6H3/t33-,34+,44?/m0/s1

Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-1',2'-dideoxyribose-3'-O-[(2-cyanoethyl)-(N,N-Diisopropyl)]-phosphoramidite; 1',2'-Dideoxy-5'-O-DMT-ribose 3'-CE phosphoramidite; dSpacer CE Phosphoramidite; (2R,3S)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; D-erythro-Pentitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

5'-Amino Modifier (BRP-02210)

Description: MMT-Hexylaminolinker Phosphoramidite is designed for use in automatic synthesizers to functionalize the sequence of the 5'end of the target oligonucleotide. The use of trityl-protected amino-modifiers is recommended when purification is required prior to use.

CAT: BRP-02210

CAS: 114616-27-2

Molecular Formula: C35H48N3O3P

Molecular Weight: 589.75

Purity: ≥95%

Appearance: Colorless to light yellow oil

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Storage: Store at -20 °C

Boiling Point: 634.0±55.0 °C at 760 mmHg

Symbol: MMT-hexylamine-linker amidite; N-MMT-C6 Amino Modifier

Formulation: Dilute with anhydrous acetonitrile

Shipping: Dry ice

InChIKey: YBANXOPIYSVPMH-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=C(C=C3)OC)OCCC#N

IUPAC Name: 3-[[di(propan-2-yl)amino]-[6-[[(4-methoxyphenyl)-diphenylmethyl]amino]hexoxy]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C35H48N3O3P/c1-29(2)38(30(3)4)42(41-28-16-25-36)40-27-15-7-6-14-26-37-35(31-17-10-8-11-18-31,32-19-12-9-13-20-32)33-21-23-34(39-5)24-22-33/h8-13,17-24,29-30,37H,6-7,14-16,26-28H2,1-5H3

Synonyms: 6-(4-Monomethoxytrityl)-hexyl-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-MMT-C6 Amino Modifier; 5'-Amino C6 Modifier Amidite

Spacer Phosphoramidite 9 (BRP-02211)

Description: Spacer phosphoramidites 9 is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required.

CAT: BRP-02211

CAS: 146668-73-7

Molecular Formula: C36H49N2O7P

Molecular Weight: 652.77

Purity: >95% by HPLC

Appearance: Colorless to light yellow oily matter

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Storage: Store at -20 °C

Boiling Point: 672.1±55.0 °C at 760 mmHg

Symbol: Spacer-9 CE

InChIKey: PEJGGZVVBQPTRG-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCCOCCOCCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC

IUPAC Name: 3-[2-[2-[2-[bis(4-methoxyphenyl)-phenylmethoxy]ethoxy]ethoxy]ethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C36H49N2O7P/c1-29(2)38(30(3)4)46(44-22-10-21-37)45-28-26-42-24-23-41-25-27-43-36(31-11-8-7-9-12-31,32-13-17-34(39-5)18-14-32)33-15-19-35(40-6)20-16-33/h7-9,11-20,29-30H,10,22-28H2,1-6H3

Synonyms: 9-O-Dimethoxytrityl-triethylene glycol, 1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2-(2-(2-(bis(4-methoxyphenyl)(phenyl)methoxy)ethoxy)ethoxy)ethyl (2-cyanoethyl) diisopropylphosphoramidite; Spacer-9 CEP; Spacer-9 Phosphoramidite; 2-[2-[2-DMT]ethoxy]ethoxy]ethyl CE phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-[2-[2-[bis(4-methoxyphenyl)phenylmethoxy]ethoxy]ethoxy]ethyl 2-cyanoethyl ester; DMTr-O-Triethyleneglycol Phosphoramidite

C3-Spacer-CEP (BRP-02213)

Description: C3-Spacer-CEP is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required.

CAT: BRP-02213

CAS: 110894-23-0

Molecular Formula: C33H43N2O5P

Molecular Weight: 578.68

Purity: ≥98.0%

Appearance: Colorless to light yellow viscous liquid

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Storage: Store at -20 °C

Boiling Point: 620.7±55.0 °C at 760 mmHg

Symbol: Spacer-C3 CEP

InChIKey: IMRNWKAKFIGPOS-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)OCCC#N

IUPAC Name: 3-(bis(4-methoxyphenyl)(phenyl)methoxy)propyl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C33H43N2O5P/c1-26(2)35(27(3)4)41(39-24-10-22-34)40-25-11-23-38-33(28-12-8-7-9-13-28,29-14-18-31(36-5)19-15-29)30-16-20-32(37-6)21-17-30/h7-9,12-21,26-27H,10-11,23-25H2,1-6H3

Synonyms: 3-(4,4'-Dimethoxytrityloxy)propyl-1-[(2-cyanoethyl)-(N,N-diisopropyl)] phosphoramidite; Spacer Phosphoramidite C3; 3-(Bis(4-methoxyphenyl)phenylmethoxy)propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 3-(bis(4-methoxyphenyl)phenylmethoxy)propyl 2-cyanoethyl ester; Spacer-C3 CEP; Spacer-C3 Phosphoramidite; 3-(Bis(4-methoxyphenyl)(phenyl)methoxy)propyl (2-cyanoethyl) diisopropyl phosphoramidite

Biotin TEG Phosphoramidite (BRP-02214)

Description: Biotin TEG Phosphoramidite incorporates a biotin label with triethylene glycol spacer, either internally or at the 5' end of an oligonucleotide. Biotin is commonly used in detection systems in conjunction with streptavidin

CAT: BRP-02214

CAS: 198080-44-3

Molecular Formula: C52H76N5O11PS

Molecular Weight: 1010.24

Purity: ≥95% by NMR

Appearance: Off-white Solid

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Storage: Store at -20 °C

Boiling Point: 1018.0±65.0 °C at 760 mmHg

Symbol: BIOTIN-TEG CEP

Formulation: Dilute with anhydrous acetonitrile

InChIKey: JHOFQGWLXUQCDS-MPUKHDSVSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC(COCCOCCOCCOCCCNC(=O)CCCCC1C2C(CS1)NC(=O)N2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[3-[2-[2-[2-[3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropoxy]ethoxy]ethoxy]ethoxy]propyl]pentanamide

InChI: InChI=1S/C52H76N5O11PS/c1-39(2)57(40(3)4)69(67-29-12-26-53)68-46(37-66-52(41-14-8-7-9-15-41,42-18-22-44(60-5)23-19-42)43-20-24-45(61-6)25-21-43)36-65-35-34-64-33-32-63-31-30-62-28-13-27-54-49(58)17-11-10-16-48-50-47(38-70-48)55-51(59)56-50/h7-9,14-15,18-25,39-40,46-48,50H,10-13,16-17,27-38H2,1-6H3,(H,54,58)(H2,55,56,59)/t46?,47-,48-,50-,69?/m0/s1

Synonyms: 1-Dimethoxytrityloxy-3-O-(N-biotinyl-3-aminopropyl)-triethyleneglycolyl-glyceryl-2-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-3,6,9,12-tetraoxa-16-azaheneicos-1-yl 2-cyanoethyl ester; Phosphoramidous acid, bis(1-methylethyl)-, 1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-21-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-17-oxo-3,6,9,12-tetraoxa-16-azaheneicos-1-yl 2-cyanoethyl ester, [3aS-(3aα,4β,6aα)]-[partial]-; Biotin-TEG CEP; Biotin TEG amidite; Biotin TEG CE Phosphoramidite

Thiol-Modifier C6 S-S (BRP-02226)

Description: Thiol-Modifier C6 S-S incorporates a thiol reactive functional group for conjugation. This disulphide product can also be used to modify the 3'-position by using the phosphoramidite as the first adduct in the oligo sequence.

CAT: BRP-02226

CAS: 148254-21-1

Molecular Formula: C42H61N2O5S2P

Molecular Weight: 769.05

Purity: >95% by HPLC

Appearance: Colorless oily matter

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Storage: Store at -20 °C

Boiling Point: 757.4±60.0 °C at 760 mmHg

InChIKey: VEONRKLBSGQZRU-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCSSCCCCCCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)OCCC#N

IUPAC Name: 3-[6-[6-[bis(4-methoxyphenyl)-phenylmethoxy]hexyldisulfanyl]hexoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C42H61N2O5PS2/c1-35(2)44(36(3)4)50(49-32-18-29-43)48-31-15-8-10-17-34-52-51-33-16-9-7-14-30-47-42(37-19-12-11-13-20-37,38-21-25-40(45-5)26-22-38)39-23-27-41(46-6)28-24-39/h11-13,19-28,35-36H,7-10,14-18,30-34H2,1-6H3

Synonyms: 1-O-Dimethoxytrityl-hexyl-disulfide, 1'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Thiol-Modifier C6 S-S CE Phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 6-[[6-[bis(4-methoxyphenyl)phenylmethoxy]hexyl]dithio]hexyl 2-cyanoethyl ester; N,N-Bis(1-methylethyl)phosphoramidous Acid [[6-[Bis(4-methoxyphenyl)phenylmethoxy]hexyl]dithio]hexyl 2-Cyanoethylester; 6-[[6-[Bis(4-methoxyphenyl)phenylmethoxy]hexyl]dithio]hexyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite

6-Hexachloro-Fluorescein Phosphoramidite (BRP-02228)

Description: A HEX phosphoramidite for yellow-green fluorescent oligonucleotides. Perfect for multiplex qPCR and genotyping assays.

CAT: BRP-02228

CAS: 1360547-55-2

Molecular Formula: C46H52N3O10Cl6P

Molecular Weight: 1050.61

Purity: ≥95%

Appearance: Off-white Solid

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Storage: Store at -20 °C

Boiling Point: 928.7±65.0 °C at 760 mmHg

Symbol: 6-HEX Phosphoramidite; 5'-Hexachloro-Fluorescein-CE Phosphoramidite (HEX)

InChIKey: RDZTYXJTMDFAOO-UHFFFAOYSA-N

Fluorescence Maximum: 549

Absorption Maximum (Lambda Max): 533

Solubility: Soluble in Acetonitrile, DCM

CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)C1=CC(=C2C(=C1Cl)C3(C4=CC(=C(C(=C4OC5=C(C(=C(C=C53)Cl)OC(=O)C(C)(C)C)Cl)Cl)OC(=O)C(C)(C)C)Cl)OC2=O)Cl)OCCC#N

IUPAC Name: [2',4,4',5',7,7'-hexachloro-6-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate

InChI: InChI=1S/C46H52Cl6N3O10P/c1-23(2)55(24(3)4)66(61-19-15-16-53)60-18-14-12-11-13-17-54-40(56)25-20-28(47)31-32(33(25)50)46(65-41(31)57)26-21-29(48)38(63-42(58)44(5,6)7)34(51)36(26)62-37-27(46)22-30(49)39(35(37)52)64-43(59)45(8,9)10/h20-24H,11-15,17-19H2,1-10H3,(H,54,56)

Synonyms: HEX phosphoramidite, 6-isomer; DyLight HEX CEP; 6-(4,7,2',4',5',7'-Hexachloro-3',6'-dipivaloylfluoresceinyl-6-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Propanoic acid, 2,2-dimethyl-, 1,1'-[6-[10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-2',4,4',5',7,7'-hexachloro-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] ester; 1,1'-[6-[10-[Bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-2',4,4',5',7,7'-hexachloro-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] bis(2,2-dimethylpropanoate); Hex-C6-amidite

Cyanine 3 Phosphoramidite (BRP-02234)

Description: Cyanine 3 Phosphoramidite is a trusted fluorescent phosphoramidite dye for DNA and RNA oligonucleotide labeling. It ensures high fluorescence yield and excellent coupling efficiency for genetic analysis.

CAT: BRP-02234

CAS: 718594-66-2

Molecular Formula: C58H70N4O4P

Molecular Weight: 918.17

Purity: >95%

Appearance: Red Solid

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Storage: Store at -20 °C

Symbol: Cy3 Phosphoramidite

InChIKey: NLVDKXRBDBBNMO-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC[N+]1=C(C(C2=CC=CC=C21)(C)C)C=CC=C3C(C4=CC=CC=C4N3CCCOC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=C(C=C7)OC)(C)C)OCCC#N

IUPAC Name: 3-[[di(propan-2-yl)amino]-[3-[2-[3-[1-[3-[(4-methoxyphenyl)-diphenylmethoxy]propyl]-3,3-dimethylindol-2-ylidene]prop-1-enyl]-3,3-dimethylindol-1-ium-1-yl]propoxy]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C58H70N4O4P/c1-44(2)62(45(3)4)67(65-42-21-38-59)66-43-23-40-61-53-31-19-17-29-51(53)57(7,8)55(61)33-20-32-54-56(5,6)50-28-16-18-30-52(50)60(54)39-22-41-64-58(46-24-12-10-13-25-46,47-26-14-11-15-27-47)48-34-36-49(63-9)37-35-48/h10-20,24-37,44-45H,21-23,39-43H2,1-9H3/q+1

Synonyms: 2-[3-[1,3-Dihydro-1-[3-(4-methoxytriphenylmethoxy)propyl]-3,3-dimethyl-2H-indol-2-ylidene]-1-propen-1-yl]-1-[3-[N,N-diisopropylamino(2-cyanoethoxy)phosphinoxy]propyl]-3,3-dimethyl-3H-indolium; 2-[3-[1-[3-[[[Bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1-propen-1-yl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-3H-indolium; 3H-Indolium, 2-[3-[1-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1-propenyl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-; 2-(3-(1-(3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)propyl)-3,3-dimethylindolin-2-ylidene)prop-1-en-1-yl)-1-(3-((4-methoxyphenyl)diphenylmethoxy)propyl)-3,3-dimethyl-3H-indol-1-ium

Related CAS: 182873-76-3 (chloride salt)

Cyanine 5 Phosphoramidite (BRP-02235)

Description: Cyanine 5 Phosphoramidite is a red-emitting fluorescent phosphoramidite used in DNA synthesis and FRET assays. It provides intense signal and superior purity for molecular diagnostics.

CAT: BRP-02235

CAS: 351186-76-0

Molecular Formula: C60H72N4O4P

Molecular Weight: 944.21

Purity: >95%

Appearance: Blue Solid

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Storage: Store at -20 °C

Symbol: Cy5 Phosphoramidite

InChIKey: WQVYZWOFBGLVGB-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC[N+]1=C(C(C2=CC=CC=C21)(C)C)C=CC=CC=C3C(C4=CC=CC=C4N3CCCOC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=C(C=C7)OC)(C)C)OCCC#N

IUPAC Name: 3-[[di(propan-2-yl)amino]-[3-[2-[5-[1-[3-[(4-methoxyphenyl)-diphenylmethoxy]propyl]-3,3-dimethylindol-2-ylidene]penta-1,3-dienyl]-3,3-dimethylindol-1-ium-1-yl]propoxy]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C60H72N4O4P/c1-46(2)64(47(3)4)69(67-44-23-40-61)68-45-25-42-63-55-33-22-20-31-53(55)59(7,8)57(63)35-18-12-17-34-56-58(5,6)52-30-19-21-32-54(52)62(56)41-24-43-66-60(48-26-13-10-14-27-48,49-28-15-11-16-29-49)50-36-38-51(65-9)39-37-50/h10-22,26-39,46-47H,23-25,41-45H2,1-9H3/q+1

Synonyms: 2-[5-[1,3-Dihydro-1-[3-(4-methoxytriphenylmethoxy)propyl]-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-[3-[N,N-diisopropylamino(2-cyanoethoxy)phosphinoxy]propyl]-3,3-dimethyl-3H-indolium; 3H-Indolium, 2-[5-[1-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-; 2-[5-[1-[3-[[[Bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-3H-indolium; 3H-Indolium, 2-[5-[1-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadienyl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-

Related CAS: 182873-67-2 (chloride salt)

Quasar 670 CE Phosphoramidite

Description: Quasar 670 dyes are cyanine derivatives of Cyanine 5. Cyanine dyes are a popular oligonucleotide modification and are commonly used for imaging, flow cytometry, and genomic applications.

CAT: BRP-02352

CAS: 1032678-33-3

Molecular Formula: C47H67F6N5O2P2

Molecular Weight: 910.02

Purity: 95%

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InChIKey: CXTKSIZCEDZHOE-PVMSMBLDNA-O

CanonicalSMILES: [P+5]([F-])([F-])([F-])([F-])([F-])[F-].C(CCCCC(N[C@@H]1CC[C@@H](OP(N(C(C)C)C(C)C)CCC#N)CC1)=O)N2C=3C(C(C)(C)C2=CC=CC=CC4=[N+](C)C=5C(C4(C)C)=CC=CC5)=CC=CC3

IUPAC Name: 1-(6-(((1r,4r)-4-(((2-cyanoethyl)(diisopropylamino)phosphaneyl)oxy)cyclohexyl)amino)-6-oxohexyl)-3,3-dimethyl-2-(5-(1,3,3-trimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-3H-indol-1-ium;hexafluorophosphate

InChI: InChI=1/C47H66N5O2P.F6P/c1-35(2)52(36(3)4)55(34-20-32-48)54-38-30-28-37(29-31-38)49-45(53)27-14-11-19-33-51-42-24-18-16-22-40(42)47(7,8)44(51)26-13-10-12-25-43-46(5,6)39-21-15-17-23-41(39)50(43)9;1-7(2,3,4,5)6/h10,12-13,15-18,21-26,35-38H,11,14,19-20,27-31,33-34H2,1-9H3;/q;-1/p+1/t37-,38-,55?;

Synonyms: 3H-Indolium, 2-[5-[1-[6-[[trans-4-[[[bis(1-methylethyl)amino](2-cyanoethyl)phosphino]oxy]cyclohexyl]amino]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1,3,3-trimethyl-, hexafluorophosphate(1-) (1:1)

Related CAS: 1032678-32-2 (free base)

Biotin-dT CE-Phosphoramidite

Description: Biotin-dT CE-Phosphoramidite is a prestigious compound, engaged in the critical tasks of labeling and detecting DNA or RNA sequences. With the amalgamation of biotin, this meticulously modified nucleotide engenders a realm of convenience for meticulous purification processes, unrivaled amplification endeavors and captivating visualization techniques.

CAT: BRP-02358

CAS: 198080-40-9

Molecular Formula: C69H89N8O12PS

Molecular Weight: 1285.55

Purity: 95%

Appearance: White, off-white to light yellow powder

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Storage: Store at -20 °C

InChIKey: FHABSPMZQJOPSS-GGVSAJPNSA-N

Solubility: Soluble in Anhydrous Acetonitrile

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C=CC(=O)NCCCCCCNC(=O)CCCCC6C7C(CS6)N(C(=O)N7)C(=O)C8=CC=C(C=C8)C(C)(C)C

IUPAC Name: 5-[(3aR,6S,6aS)-3-(4-tert-butylbenzoyl)-2-oxo-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]-N-[6-[3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoylamino]hexyl]pentanamide

InChI: InChI=1S/C69H89N8O12PS/c1-46(2)77(47(3)4)90(87-41-19-38-70)89-57-42-62(88-58(57)44-86-69(51-20-13-12-14-21-51,52-29-33-54(84-8)34-30-52)53-31-35-55(85-9)36-32-53)75-43-49(64(80)74-66(75)82)26-37-61(79)72-40-18-11-10-17-39-71-60(78)23-16-15-22-59-63-56(45-91-59)76(67(83)73-63)65(81)48-24-27-50(28-25-48)68(5,6)7/h12-14,20-21,24-37,43,46-47,56-59,62-63H,10-11,15-19,22-23,39-42,44-45H2,1-9H3,(H,71,78)(H,72,79)(H,73,83)(H,74,80,82)/t56-,57-,58+,59-,62+,63-,90?/m0/s1

Synonyms: 5'-Dimethoxytrityloxy-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Biotin-dT Amidite; Biotin-dT Phosphoramidite; (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-(3-((6-(5-((3aS,4S,6aR)-1-(4-(tert-butyl)benzoyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexyl)amino)-3-oxoprop-1-en-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMTr-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-dT-3'-CE-phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxythymidine-3'-O-[(2-cyanoethyl)-N,N-diisopropyl]-phosphoramidite; Biotin-dT

3'-O-DMT-N6-Benzoyl-Cytidine TNA 2'-CE phosphoramidite

Description: TNA 2'-CE oligonucleotide synthesis necessitates 3'-O-DMT-N6-benzoyl-cytidine, and our TNA 2'-CE phosphoramidite is precisely engineered for just that purpose. Researchers within the biomedicine discipline rely heavily on our product due to their capacity to incorporate TNA monomers as they fabricate artificial nucleic acids for gene-based therapeutics and pharmacological advancement.

CAT: BRP-02365

CAS: 325683-96-3

Molecular Formula: C45H50N5O8P

Molecular Weight: 819.90

Purity: 98%

Size	Price	Stock	Quantity
1 g	$998	In stock
100 mg	$398	In stock

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InChIKey: URCWUOWKRJMYKD-RBZSHJCZSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(COC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)OC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

IUPAC Name: N-[1-[(2R,3R,4S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C45H50N5O8P/c1-31(2)50(32(3)4)59(56-29-13-27-46)58-41-39(30-55-43(41)49-28-26-40(48-44(49)52)47-42(51)33-14-9-7-10-15-33)57-45(34-16-11-8-12-17-34,35-18-22-37(53-5)23-19-35)36-20-24-38(54-6)25-21-36/h7-12,14-26,28,31-32,39,41,43H,13,29-30H2,1-6H3,(H,47,48,51,52)/t39-,41+,43+,59?/m0/s1

Synonyms: Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; DMTr-TNA C(Bz)-amidite; (2R,3R,4S)-2-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; TNA-C(Bz)-CE-Phosphoramidite; N-Benzoyl-1-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]cytosine; DMTr-TNA-C(Bz)-Phosphoramidite