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Phosphoramidites

2'-Modified Phosphoramidites
(549/549)
2'-Phosphoramidites
(27/27)
3'-Modified Phosphoramidites
(201/201)
5'-Modified Phosphoramidites
(34/34)
Arabino Phosphoramidites
(24/24)
Base Protected Phosphoramidites (435/435) Dye Phosphoramidites
(63/63)
Label Phosphoramidites
(81/81)
Linker Phosphoramidites
(97/97)
Other Phosphoramidites
(94/94)
PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12)
Reverse Phosphoramidites
(25/25)
Spacer Phosphoramidites
(24/24)
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5-Br-rU Phosphoramidite

Description: 5-Br-rU Phosphoramidite, a vital constituent in biomedical research and drug development, finds utility as a building block for oligonucleotide union and holds immense potential in therapies for diseases like cancer and viral infections. Notably, owing to its distinctive chemical features, it can tinker with the structure and function of nucleic acids, facilitating precise treatment, and improved delivery of medications.
CAT: BRP-00243
CAS: 166733-98-8
Molecular Formula: C45H60BrN4O9PSi
Molecular Weight: 939.96
Purity: ≥97% by HPLC
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Storage: Store at -20 °C
InChIKey: URWJXIOFFASYFA-IPXQPGKOSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=C(Br)C(=O)NC2=O)C1O[Si](C)(C)C(C)(C)C)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C45H60BrN4O9PSi/c1-30(2)50(31(3)4)60(56-27-15-26-47)58-39-38(57-42(40(39)59-61(10,11)44(5,6)7)49-28-37(46)41(51)48-43(49)52)29-55-45(32-16-13-12-14-17-32,33-18-22-35(53-8)23-19-33)34-20-24-36(54-9)25-21-34/h12-14,16-25,28,30-31,38-40,42H,15,27,29H2,1-11H3,(H,48,51,52)/t38-,39-,40-,42-,60?/m1/s1
Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-bromo-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-5-bromo-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine; 5-Bromo-2'-O-tert-butylbutyldimethylsilyl-5'-O-DMT-D-uridine 3'-CE phosphoramidite; Br-U-CE Phosphoramidite; 5-Bromo Uridine CED phosphoramidite; 5-Bromo 2'-TBDMS Uridine 3'-CE phosphoramidite; DMTr-2'-O-TBDMS-5-Br-rU-3'-CE-Phosphoramidite

5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite

Description: 5'-O-DMT-2'-O-methylinosine 3'-CE phosphoramidite is a vital component used in the research and development of RNA molecules for biomedical research. It functions as a phosphoramidite building block to introduce the modified nucleoside 5'-O-DMT-2'-O-methylinosine into RNA sequences. This modified nucleoside plays a crucial role in studying the structure, function and therapeutic potential of RNA molecules involved in various diseases, including cancer and genetic disorders.
CAT: BRP-00244
CAS: 128219-85-2
Molecular Formula: C41H49N6O8P
Molecular Weight: 784.83
Purity: ≥98%
Appearance: White to off-white powder
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Storage: Store at -20 °C
InChIKey: PVFNTYBGWVZMCX-HLHZJIEZSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OC)N2C=NC3=C2N=CNC3=O)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC
IUPAC Name: 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxy-5-(6-oxo-1H-purin-9-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C41H49N6O8P/c1-27(2)47(28(3)4)56(53-23-11-22-42)55-36-34(54-40(37(36)51-7)46-26-45-35-38(46)43-25-44-39(35)48)24-52-41(29-12-9-8-10-13-29,30-14-18-32(49-5)19-15-30)31-16-20-33(50-6)21-17-31/h8-10,12-21,25-28,34,36-37,40H,11,23-24H2,1-7H3,(H,43,44,48)/t34-,36-,37-,40-,56?/m1/s1
Synonyms: 2'-OMe-I-CE Phosphoramidite; 2'-O-Methyl Inosine Phosphoramidite; 5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl inosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-inosine-3'-cyanoethyl phosphoramidite; Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 5'-Dimethoxytrityl-Inosine, 2'-O-methyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2'-O-Methyl Inosine CED phosphoramidite; 2'-O-Methyl-I CEP

5'-CDPI3 MGB™ Phosphoramidite

Description: 5'-CDPI3 MGB Phosphoramidite is a cutting-edge compound used in the development of drugs for studying various diseases. By utilizing its unique properties, this phosphoramidite aids in the research and development of nucleotide analogs, facilitating the discovery of potential therapeutic compounds targeting specific diseases.
CAT: BRP-00245
CAS: 1419845-08-1
Molecular Formula: C67H82F3N10O13P
Molecular Weight: 1323.42
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Storage: Store at -20°C
InChIKey: AVLXKOFWVIDHMN-UHFFFAOYSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CCOC(=O)N1C2=C(C=C1C(=O)N3CCC4=C3C=CC5=C4C=C(N5C(=O)OCC)C(=O)N6CCC7=C6C=CC8=C7C=C(N8C(=O)OCC)C(=O)N(C)CCCCCCN(C)C(=O)C(F)(F)F)C9=C(C=C2)N(CC9)C(=O)CCCCCOP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: ethyl 6-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexanoyl]-2-[3-ethoxycarbonyl-2-[3-ethoxycarbonyl-2-[methyl-[6-[methyl-(2,2,2-trifluoroacetyl)amino]hexyl]carbamoyl]-7,8-dihydropyrrolo[3,2-e]indole-6-carbonyl]-7,8-dihydropyrrolo[3,2-e]indole-6-carbonyl]-7,8-dihydropyrrolo[3,2-e]indole-3-carboxylate
InChI: InChI=1S/C67H82F3N10O13P/c1-10-89-64(86)77-53-26-23-51-45(47(53)39-56(77)60(82)72(8)32-17-13-14-18-33-73(9)63(85)67(68,69)70)29-35-75(51)62(84)58-41-49-46-30-36-76(52(46)24-27-55(49)79(58)66(88)91-12-3)61(83)57-40-48-44-28-34-74(50(44)22-25-54(48)78(57)65(87)90-11-2)59(81)21-16-15-19-37-92-94(93-38-20-31-71)80(42(4)5)43(6)7/h22-27,39-43H,10-21,28-30,32-38H2,1-9H3
Synonyms: 6-(6-(Ethoxycarbonyl)-7-(6-(ethoxycarbonyl)-7-(6-(ethoxycarbonyl)-7-(methyl(6-(2,2,2-trifluoro-N-methylacetamido)hexyl)carbamoyl)-1,2,3,6-tetrahydropyrrolo[3,2-e]indole-3-carbonyl)-1,2,3,6-tetrahydropyrrolo[3,2-e]indole-3-carbonyl)-1,2-dihydropyrrolo[3,2-e]indol-3(6H)-yl)-6-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Benzo[1,2-b:4,3-b']dipyrrole-3(6H)-carboxylic acid, 6-[[6-[6-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]-1-oxohexyl]-3-(ethoxycarbonyl)-3,6,7,8-tetrahydrobenzo[1,2-b:4,3-b']dipyrrol-2-yl]carbonyl]-2-[[6-(ethoxycarbonyl)-1,6-dihydro-7-[[methyl[6-[methyl(2,2,2-trifluoroacetyl)amino]hexyl]amino]carbonyl]benzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-7,8-dihydro-, ethyl ester; Ethyl 6-[[6-[6-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]-1-oxohexyl]-3-(ethoxycarbonyl)-3,6,7,8-tetrahydrobenzo[1,2-b:4,3-b']dipyrrol-2-yl]carbonyl]-2-[[6-(ethoxycarbonyl)-1,6-dihydro-7-[[methyl[6-[methyl(2,2,2-trifluoroacetyl)amino]hexyl]amino]carbonyl]benzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-7,8-dihydrobenzo[1,2-b:4,3-b']dipyrrole-3(6H)-carboxylate; 5'-CDPI3 MGB Phosphoramidite

2-Cyanoethyl 6-[(2-methyl-1-oxo-2-propen-1-yl)amino]hexyl N,N-bis(1-methylethyl)phosphoramidite

Description: 2-Cyanoethyl 6-[(2-methyl-1-oxo-2-propen-1-yl)amino]hexyl N,N-bis(1-methylethyl)phosphoramidite is a phosphoramidite reagent used in solid-phase oligonucleotide synthesis. This reagent is employed in the synthesis of modified nucleotides and oligonucleotides, particularly for introducing functionalities or labels into nucleic acids for various applications in molecular biology, such as site-specific modification, RNA interference, and antisense technology.
CAT: BRP-00248
CAS: 1226983-36-3
Molecular Formula: C19H36N3O3P
Molecular Weight: 385.48
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Storage: Store at -20 °C
InChIKey: DZRKHCTWELOFAU-UHFFFAOYSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)C(=C)C)OCCC#N
IUPAC Name: N-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]-2-methylprop-2-enamide
InChI: InChI=1S/C19H36N3O3P/c1-16(2)19(23)21-13-9-7-8-10-14-24-26(25-15-11-12-20)22(17(3)4)18(5)6/h17-18H,1,7-11,13-15H2,2-6H3,(H,21,23)
Synonyms: Methacrylate C6 Phosphoramidite; 6-methacrylamido-hexyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 6-[(2-methyl-1-oxo-2-propen-1-yl)amino]hexyl ester; 5'-Acrydite Amidite; Methacrylate C6 Amidite

5'-Amino-Modifier 5

Description: Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl[2-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]ethoxy]ethyl] ester is an intricate biomedical compound, manifesting remarkable potential as a therapeutic agent for targeted drug delivery. Its distinctive mechanism centers on precise cellular pathway targeting, facilitating the hinderance of malignant proliferation and dissemination.
CAT: BRP-00251
CAS: 612548-86-4
Molecular Formula: C33H44N3O4P
Molecular Weight: 577.69
Appearance: Light-yellow Oil
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Storage: Store at -20°C
Boiling Point: 620.3±55.0 °C at 760 mmHg
InChIKey: VPCIMMMVDXMIED-UHFFFAOYSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCCOCCNC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=C(C=C3)OC
IUPAC Name: 3-[[di(propan-2-yl)amino]-[2-[2-[[(4-methoxyphenyl)-diphenylmethyl]amino]ethoxy]ethoxy]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C33H44N3O4P/c1-27(2)36(28(3)4)41(39-23-12-21-34)40-26-25-38-24-22-35-33(29-13-8-6-9-14-29,30-15-10-7-11-16-30)31-17-19-32(37-5)20-18-31/h6-11,13-20,27-28,35H,12,22-26H2,1-5H3
Synonyms: 2-[2-(4-Monomethoxytrityl)aminoethoxy]ethyl-(2-cyanoethyl)-N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl [2-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]ethoxy]ethyl] ester; 2-Cyanoethyl [2-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]ethoxy]ethyl] N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 2-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]ethoxy]ethyl ester

5'-DMS(O)MT-Amino-Modifier C6

Description: 5'-DMS(O)MT-Amino-Modifier C6, a unique oligonucleotide modification derivative utilized as a DNA probe for biomedical research, offers selective DNA fragment labeling for fluorescent detection, hybridization assays, and gene expression analysis.
CAT: BRP-00252
CAS: 1173109-53-9
Molecular Formula: C37H52N3O5PS
Molecular Weight: 681.34
Purity: NMR 1H, 31P, HPLC (95%)
Appearance: yellowish viscous oil
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Storage: Store at -20°C
Boiling Point: 731.2±60.0 °C at 760 mmHg
InChIKey: AEUCXPPPONCIRE-UHFFFAOYSA-N
Solubility: soluble in acetonitrile, dichloromethane
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(C1=CC=C(C=C1)OC)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)S(=O)C)OCCC#N
IUPAC Name: 3-[6-[[bis(4-methoxyphenyl)-(4-methylsulfinylphenyl)methyl]amino]hexoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C37H52N3O5PS/c1-29(2)40(30(3)4)46(45-28-12-25-38)44-27-11-9-8-10-26-39-37(31-13-19-34(42-5)20-14-31,32-15-21-35(43-6)22-16-32)33-17-23-36(24-18-33)47(7)41/h13-24,29-30,39H,8-12,26-28H2,1-7H3
Synonyms: DMS(O)MT aminolink C6; 6-(4,4'-Dimethoxy-4''-methylsulfonyl-tritylamino)hexyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 6-[[bis(4-methoxyphenyl)[4-(methylsulfinyl)phenyl]methyl]amino]hexyl 2-cyanoethyl ester; 6-[[Bis(4-methoxyphenyl)[4-(methylsulfinyl)phenyl]methyl]amino]hexyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite

Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite

Description: Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite is an indispensible compound, catering to the synthesis of modified oligonucleotides. Its application in drug R&D facilitates the investigation of nucleic acid interactions and chemical alterations.
CAT: BRP-00253
CAS: 1173797-55-1
Molecular Formula: C37H45N2O6P
Molecular Weight: 644.74
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Storage: Store at -20 °C
InChIKey: SGSVNADNKJQVBP-OFEIKZNSSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)C#C
IUPAC Name: 3-[[(2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-ethynyloxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C37H45N2O6P/c1-8-32-25-35(45-46(43-24-12-23-38)39(27(2)3)28(4)5)36(44-32)26-42-37(29-13-10-9-11-14-29,30-15-19-33(40-6)20-16-30)31-17-21-34(41-7)22-18-31/h1,9-11,13-22,27-28,32,35-36H,12,24-26H2,2-7H3/t32-,35-,36+,46?/m0/s1
Synonyms: 1-Ethynyl-dSpacer CE Phosphoramidite; 5'-O-Dimethoxytrityl-1'-ethynyl-2'-deoxyribose-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; D-ribo-Hept-1-ynitol, 3,6-anhydro-7-O-[bis(4-methoxyphenyl)phenylmethyl]-1,2,4-trideoxy-, 5-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

5'-Aminooxy-Modifier-11-CE Phosphoramidite

Description: 5'-Aminooxy-Modifier-11-CE Phosphoramidite is a critical component in the synthesis of modified RNA oligonucleotides used in biomedical research. This product is used to introduce aminooxy modifications into the RNA sequence, allowing for specific chemical conjugation reactions with drugs or disease biomarkers. These modified oligonucleotides can be used to study disease mechanisms, develop targeted drug delivery systems, and support gene therapy research.
CAT: BRP-00254
Molecular Formula: C38H54N3O8P
Molecular Weight: 711.82
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Storage: Store at 2-8 °C
InChIKey: HQAZEHVGEGYDBR-UHFFFAOYSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCCOCCOCCOCCONC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC
IUPAC Name: 3-[2-[2-[2-[2-[[bis(4-methoxyphenyl)-phenylmethyl]amino]oxyethoxy]ethoxy]ethoxy]ethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C38H54N3O8P/c1-31(2)41(32(3)4)50(48-22-10-21-39)49-30-28-46-26-24-44-23-25-45-27-29-47-40-38(33-11-8-7-9-12-33,34-13-17-36(42-5)18-14-34)35-15-19-37(43-6)20-16-35/h7-9,11-20,31-32,40H,10,22-30H2,1-6H3
Synonyms: 10-[N-Dimethoxytrityl-aminooxyethyl)]-triethyleneglycol-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-DMT-Aminooxy-PEG4-phosphoramidite

Biotin CE Phosphoramidite

Description: Biotin CE Phosphoramidite is a biomolecule unparalleled in its intricacy and complexity, crucial to the synthesis of DNA strands. This exceptional product, with its multifarious biomedical applications, has been meticulously crafted to facilitate the generation of oligonucleotide probes tailored to the detection of malignant phenomena like cancer; further enhanced by its ability to expedite drug development studies.
CAT: BRP-00256
CAS: 147190-34-9
Molecular Formula: C47H66N5O7PS
Molecular Weight: 876.11
Purity: >95% by HPLC
Appearance: Off-white Solid
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Storage: Store at -20°C
InChIKey: GMVCCUAXEMZEJE-OYSBNFJTSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(CCCCNC(=O)CCCCC1C2C(CS1)NC(=O)N2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
IUPAC Name: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]pentanamide
InChI: InChI=1S/C47H66N5O7PS/c1-34(2)52(35(3)4)60(58-30-14-28-48)59-32-36(15-12-13-29-49-44(53)19-11-10-18-43-45-42(33-61-43)50-46(54)51-45)31-57-47(37-16-8-7-9-17-37,38-20-24-40(55-5)25-21-38)39-22-26-41(56-6)27-23-39/h7-9,16-17,20-27,34-36,42-43,45H,10-15,18-19,29-33H2,1-6H3,(H,49,53)(H2,50,51,54)/t36?,42-,43-,45-,60?/m0/s1
Synonyms: N-[6-[[(Diisopropylamino)(2-cyanoethoxy)phosphino]oxy]-5-[(4,4'-dimethoxytrityloxy)methyl]hexyl]-5-(2-oxo-1,3,3abeta,4,6,6abeta-hexahydro-2H-thieno[3,4-d]imidazole-4alpha-yl)pentanamide

DesthiobiotinTEG Phosphoramidite

Description: DesthiobiotinTEG Phosphoramidite is a vital tool in molecular biology for the synthesis of labeled oligonucleotides. By incorporating this innovative phosphoramidite during DNA synthesis, researchers can generate biotinylated oligonucleotides lacking the intrinsic biotin-avidin affinity. This product is highly beneficial for applications such as DNA labeling is affinity chromatography and bioconjugation for studying biomolecular interactions.
CAT: BRP-00257
Molecular Formula: C52H78N5O11P
Molecular Weight: 980.19
Purity: ≥95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: FNYRRUVUJMFYFL-LAMWNFHDSA-N
CanonicalSMILES: CC1C(NC(=O)N1)CCCCCC(=O)NCCCOCCOCCOCCOCC(COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[3-[2-[2-[2-[3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropoxy]ethoxy]ethoxy]ethoxy]propyl]-6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanamide
InChI: InChI=1S/C52H78N5O11P/c1-40(2)57(41(3)4)69(67-31-14-28-53)68-48(39-66-52(43-16-10-8-11-17-43,44-20-24-46(60-6)25-21-44)45-22-26-47(61-7)27-23-45)38-65-37-36-64-35-34-63-33-32-62-30-15-29-54-50(58)19-13-9-12-18-49-42(5)55-51(59)56-49/h8,10-11,16-17,20-27,40-42,48-49H,9,12-15,18-19,29-39H2,1-7H3,(H,54,58)(H2,55,56,59)/t42-,48?,49+,69?/m0/s1
Synonyms: 1-Dimethoxytrityloxy-3-O-(N-desthiobiotinyl-3-aminopropyl)-triethyleneglycolyl-glyceryl-2-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 1,1-Bis(4-methoxyphenyl)-25-((4R,5S)-5-methyl-2-oxoimidazolidin-4-yl)-20-oxo-1-phenyl-2,6,9,12,15-pentaoxa-19-azapentacosan-4-yl (2-cyanoethyl) diisopropylphosphoramidite; Desthiobiotin TEG Phosphoramidite

Fluorescein Phosphoramidite

Description: Fluorescein Phosphoramidite is an essential compound employed ubiquitously in the realm of biomedical sciences, exhibiting significance for both DNA synthesand modification. Its versatility as a fluorescent marker not only augments the fabrication of diverse diagnostic tools encompassing nucleic acid probes and sensors but also promotes research endeavors concerning DNA sequencing, gene expression analysis and detection of disease-associated genetic mutations.
CAT: BRP-00258
CAS: 178925-53-6
Molecular Formula: C68H79N4O12PS
Molecular Weight: 1207.50
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Storage: Store at 2-8°C
InChIKey: NTIKJRRCLOXTQM-UHFFFAOYSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(CCCCNC(=S)NC1=CC2=C(C=C1)C3(C4=C(C=C(C=C4)OC(=O)C(C)(C)C)OC5=C3C=CC(=C5)OC(=O)C(C)(C)C)OC2=O)COC(C6=CC=CC=C6)(C7=CC=C(C=C7)OC)C8=CC=C(C=C8)OC
IUPAC Name: [5-[[5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]carbamothioylamino]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C68H79N4O12PS/c1-44(2)72(45(3)4)85(79-38-18-36-69)80-43-46(42-78-67(47-20-14-13-15-21-47,48-22-27-51(76-11)28-23-48)49-24-29-52(77-12)30-25-49)19-16-17-37-70-64(86)71-50-26-33-56-55(39-50)61(73)84-68(56)57-34-31-53(81-62(74)65(5,6)7)40-59(57)83-60-41-54(32-35-58(60)68)82-63(75)66(8,9)10/h13-15,20-35,39-41,44-46H,16-19,37-38,42-43H2,1-12H3,(H2,70,71,86)
Synonyms: 1-Dimethoxytrityloxy-2-(N-thiourea-(di-O-pivaloyl-fluorescein)-4-aminobutyl)-propyl-3-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite

Cholesteryl-TEG Phosphoramidite

Description: Cholesteryl-TEG Phosphoramidite is an indispensable component in the biomedical sector, exemplifing its significance by facilitating the research and development of altered nucleotides. Its pivotal contribution lies in propelling the progress of groundbreaking pharmaceuticals and therapeutics aimed at studying malignancies, viral affections and hereditary anomalies.
CAT: BRP-00260
CAS: 873435-29-1
Molecular Formula: C70H106N3O11P
Molecular Weight: 1196.60
Purity: 95%
Appearance: Colorless to faint yellow oily matter
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InChIKey: FNJSTUYYFCEZCA-PORNTWEGSA-N
CanonicalSMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC(=O)NCCCOCCOCCOCCOCC(COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N)C)C
IUPAC Name: [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] N-[3-[2-[2-[2-[3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropoxy]ethoxy]ethoxy]ethoxy]propyl]carbamate
InChI: InChI=1S/C70H106N3O11P/c1-51(2)18-15-19-54(7)64-32-33-65-63-31-26-58-48-61(34-36-68(58,8)66(63)35-37-69(64,65)9)83-67(74)72-39-17-40-77-42-43-78-44-45-79-46-47-80-49-62(84-85(82-41-16-38-71)73(52(3)4)53(5)6)50-81-70(55-20-13-12-14-21-55,56-22-27-59(75-10)28-23-56)57-24-29-60(76-11)30-25-57/h12-14,20-30,51-54,61-66H,15-19,31-37,39-50H2,1-11H3,(H,72,74)/t54-,61+,62?,63+,64-,65+,66+,68+,69-,85?/m1/s1
Synonyms: 1-Dimethoxytrityloxy-3-O-(N-cholesteryl-3-aminopropyl)-triethyleneglycol-glyceryl-2-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Cholest-5-en-3-ol (3β)-, 3-[17-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-19-[bis(1-methylethyl)amino]-22-cyano-6,9,12,15,18,20-hexaoxa-2-aza-19-phosphadocosanoate]; Cholesteryl TEG phosphoramidite; Cholest-5-en-3-ol (3β)-, 17-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-19-[bis(1-methylethyl)amino]-22-cyano-6,9,12,15,18,20-hexaoxa-2-aza-19-phosphadocosanoate; Dimethoxytrityloxy-3-O-(N-cholesteryl-3-aminopropyl)triethyleneglycol-glyceryl-2-O-(2-cyanoethyl)(N,N-diisopropyl)phosphoramidite; DMTr-Cholesteryl-TEG Phosphoramidite (plant source); 1-O-(4,4'-dimethoxytrityl)-3-O-(N-cholesteryl-3-aminopropyl)-triethyleneglycol-glyceryl-2-O-(2-cyanoethyl)-(N,N-diisopropyl) Phosphoramidite; DMT-Cholesterol (Plant) TEG CE phosphoramidite

Psoralen-C2 CEP

Description: Psoralen-C2 CEP is an innovative biomedical compound, used for studying a myriad of skin afflictions, particularly psoriasand vitiligo. It is derived from psoralen, an organic constituent inherent to select flora.
CAT: BRP-00261
CAS: 126221-83-8
Molecular Formula: C26H35N2O6P
Molecular Weight: 502.55
Purity: 95%
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InChIKey: DBDHKKULBPYUPD-UHFFFAOYSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC1=CC(=O)OC2=C(C3=C(C=C12)C(=C(O3)C)COCCOP(N(C(C)C)C(C)C)OCCC#N)C
IUPAC Name: 3-[[di(propan-2-yl)amino]-[2-[(2,5,9-trimethyl-7-oxofuro[3,2-g]chromen-3-yl)methoxy]ethoxy]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C26H35N2O6P/c1-16(2)28(17(3)4)35(31-10-8-9-27)32-12-11-30-15-23-20(7)33-26-19(6)25-21(14-22(23)26)18(5)13-24(29)34-25/h13-14,16-17H,8,10-12,15H2,1-7H3
Synonyms: 2-[4'-(hydroxymethyl)-4,5',8-trimethylpsoralen]-ethyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Psoralen C2 Phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 2-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]ethyl ester; 2-Cyanoethyl (2-((2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)methoxy)ethyl) diisopropylphosphoramidite; Psoralen C-2 CED phosphoramidite

Psoralen C6 Phosphoramidite

Description: Psoralen C6 Phosphoramidite is an indispensable compound, finding extensive employment in DNA synthesis and modification. This remarkable product effectively facilitates the incorporation of psoralen derivatives into oligonucleotides, thereby enabling the research of an extensive array of afflictions encompassing cancer and dermatological conditions.
CAT: BRP-00262
CAS: 518046-08-7
Molecular Formula: C30H43N2O6P
Molecular Weight: 558.65
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InChIKey: VBVUJRRJLYZYNP-UHFFFAOYSA-N
CanonicalSMILES: CC1=CC(=O)OC2=C(C3=C(C=C12)C(=C(O3)C)COCCCCCCOP(N(C(C)C)C(C)C)OCCC#N)C
IUPAC Name: 3-[[di(propan-2-yl)amino]-[6-[(2,5,9-trimethyl-7-oxofuro[3,2-g]chromen-3-yl)methoxy]hexoxy]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C30H43N2O6P/c1-20(2)32(21(3)4)39(36-16-12-13-31)35-15-11-9-8-10-14-34-19-27-24(7)37-30-23(6)29-25(18-26(27)30)22(5)17-28(33)38-29/h17-18,20-21H,8-12,14-16,19H2,1-7H3
Synonyms: 6-[4'-(Hydroxymethyl)-4,5',8-trimethylpsoralen]-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 6-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]hexyl ester; Psoralen C-6 CED phosphoramidite; 2-Cyanoethyl 6-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]hexyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 6-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]hexyl ester; Psoralen-C6 CEP

DNP-TEG CEP

Description: DNP-TEG CEP is a prominent biomedical compound, used in research of mitochondrial dysfunction. In its remarkable capacity as a mitochondrial uncoupler, it efficaciously facilitates energy dissipation while curbing ATP synthesis. Notably, this revolutionary compound exhibits immense promise in studying the burden of metabolic disorders like obesity and diabetes.
CAT: BRP-00263
CAS: 1027512-01-1
Molecular Formula: C48H64N5O13P
Molecular Weight: 950.02
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InChIKey: QMUUCQCGRWITRM-UHFFFAOYSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: N#CCCOP(OC(COCCOCCOCCOCCCNC1=CC=C(C=C1N(=O)=O)N(=O)=O)COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N(C(C)C)C(C)C
IUPAC Name: 2-cyanoethyl (18-((2,4-dinitrophenyl)amino)-1,1-bis(4-methoxyphenyl)-1-phenyl-2,6,9,12,15-pentaoxaoctadecan-4-yl) diisopropylphosphoramidite
InChI: InChI=1S/C48H64N5O13P/c1-37(2)51(38(3)4)67(65-27-10-24-49)66-45(35-63-33-32-62-31-30-61-29-28-60-26-11-25-50-46-23-18-42(52(54)55)34-47(46)53(56)57)36-64-48(39-12-8-7-9-13-39,40-14-19-43(58-5)20-15-40)41-16-21-44(59-6)22-17-41/h7-9,12-23,34,37-38,45,50H,10-11,25-33,35-36H2,1-6H3
Synonyms: 1-Dimethoxytrityloxy-3-O-[N-(2,4-dinitrophenyl)-3-N-aminopropyl-(triethyleneglycol)]-glyceryl-2-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; DNP-TEG Phosphoramidite; 1-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-15-[(2,4-dinitrophenyl)amino]-3,6,9,12-tetraoxapentadec-1-yl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-15-[(2,4-dinitrophenyl)amino]-3,6,9,12-tetraoxapentadec-1-yl 2-cyanoethyl ester; DNP-TEG CED phosphoramidite

Dithiol Serinol Phosphoramidite

Description: Dithiol Serinol Phosphoramidite is a key component in the synthesis of mRNA vaccines used to combat diseases like COVID-19. This compound provides a crucial thiol group that creates a stable linkage between mRNA and its delivery vehicle, enabling efficient cellular uptake and protein translation.
CAT: BRP-00265
Molecular Formula: C44H61N4O7PS2
Molecular Weight: 853.08
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Storage: Store at -20 °C
InChIKey: DVWHOVJDNIOLBR-NDSIFBHOSA-N
Solubility: Soluble in Anhydrous Acetonitrile
IUPAC Name: 2-(3-(5-((R)-1,2-dithiolan-3-yl)pentanamido)propanamido)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C44H61N4O7PS2/c1-33(2)48(34(3)4)56(54-29-12-27-45)55-32-38(47-43(50)25-28-46-42(49)16-11-10-15-41-26-30-57-58-41)31-53-44(35-13-8-7-9-14-35,36-17-21-39(51-5)22-18-36)37-19-23-40(52-6)24-20-37/h7-9,13-14,17-24,33-34,38,41H,10-12,15-16,25-26,28-32H2,1-6H3,(H,46,49)(H,47,50)/t38?,41-,56?/m1/s1
Synonyms: 3-Dimethoxytrityloxy-2-(3-((R)-α-lipoamido)propanamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite

Protected Biotin Serinol Phosphoramidite

Description: Protected Biotin Serinol Phosphoramidite is a biomedicine product used in DNA synthesis for biotin labeling. It serves as a phosphate protecting agent during the synthesis of biotinylated oligonucleotides used in disease diagnostics, gene expression analysis, and biosensor development.
CAT: BRP-00266
CAS: 1275574-85-0
Molecular Formula: C57H75N6O9PS
Molecular Weight: 1051.28
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InChIKey: FKQJXAHANDDQSD-IKNNSCCISA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: N#CCCOP(OCC(NC(=O)CCNC(=O)CCCCC1SCC2N(C(=O)NC12)C(=O)C3=CC=C(C=C3)C(C)(C)C)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: 3-(bis(4-methoxyphenyl)(phenyl)methoxy)-2-(3-(5-((3aS,4S,6aR)-1-(4-(tert-butyl)benzoyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)propanamido)propyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C57H75N6O9PS/c1-39(2)63(40(3)4)73(71-35-15-33-58)72-37-46(36-70-57(43-16-11-10-12-17-43,44-24-28-47(68-8)29-25-44)45-26-30-48(69-9)31-27-45)60-52(65)32-34-59-51(64)19-14-13-18-50-53-49(38-74-50)62(55(67)61-53)54(66)41-20-22-42(23-21-41)56(5,6)7/h10-12,16-17,20-31,39-40,46,49-50,53H,13-15,18-19,32,34-38H2,1-9H3,(H,59,64)(H,60,65)(H,61,67)/t46?,49-,50-,53-,73?/m0/s1
Synonyms: 3-Dimethoxytrityloxy-2-(3-((4-t-butylbenzoyl)-biotinyl)propanamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 3-[Bis(4-methoxyphenyl)phenylmethoxy]-2-[[3-[[5-[(3aS,4S,6aR)-1-[4-(1,1-dimethylethyl)benzoyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-1-oxopropyl]amino]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 3-[bis(4-methoxyphenyl)phenylmethoxy]-2-[[3-[[5-[(3aS,4S,6aR)-1-[4-(1,1-dimethylethyl)benzoyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-1-oxopropyl]amino]propyl 2-cyanoethyl ester

6-Fluorescein Serinol Phosphoramidite

Description: A serinol-linked FAM phosphoramidite improving aqueous stability and coupling. Ideal for robust, high-yield fluorescent oligo synthesis.
CAT: BRP-00267
CAS: 1275574-87-2
Molecular Formula: C67H75N4O14P
Molecular Weight: 1191.30
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Storage: Store at -20°C
InChIKey: GIUBJQWDYGXGQR-UHFFFAOYSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)NC(=O)CCNC(=O)C4=CC5=C(C=C4)C(=O)OC56C7=C(C=C(C=C7)OC(=O)C(C)(C)C)OC8=C6C=CC(=C8)OC(=O)C(C)(C)C
IUPAC Name: [6-[[3-[[1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]amino]-3-oxopropyl]carbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C67H75N4O14P/c1-42(2)71(43(3)4)86(80-36-16-34-68)81-41-48(40-79-66(45-17-14-13-15-18-45,46-20-24-49(77-11)25-21-46)47-22-26-50(78-12)27-23-47)70-59(72)33-35-69-60(73)44-19-30-53-56(37-44)67(85-61(53)74)54-31-28-51(82-62(75)64(5,6)7)38-57(54)84-58-39-52(29-32-55(58)67)83-63(76)65(8,9)10/h13-15,17-32,37-39,42-43,48H,16,33,35-36,40-41H2,1-12H3,(H,69,73)(H,70,72)
Synonyms: 3-Dimethoxytrityloxy-2-(3-(6-carboxy-(di-O-pivaloyl-fluorescein)propanamido)propyl)-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Propanoic acid, 2,2-dimethyl-, 1,1'-[6-[7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-1,5-dioxo-9,11-dioxa-2,6-diaza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] ester; 1,1'-[6-[7-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-1,5-dioxo-9,11-dioxa-2,6-diaza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] bis(2,2-dimethylpropanoate)

Protected BiotinLC Serinol Phosphoramidite

Description: Protected BiotinLC Serinol Phosphoramidite, a derivative of biotin and serinol, has been clinically proven to be an exceptional and highly-effective reagent for synthesizing DNA and RNA probes. With its myriad of applications, this reagent is a versatile choice for professionals in the field of tissue imaging and protein interaction studies. A key component in the creation of oligonucleotides, aptamers, and siRNA, Protected BiotinLC Serinol Phosphoramidite deftly performs a plethora of bioanalytical tasks with the utmost precision and accuracy.
CAT: BRP-00268
Molecular Formula: C68H96N7O14PS
Molecular Weight: 1298.57
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InChIKey: LLAFADMXMWCLJQ-XRKNHYQJSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)CCCCC4C5C(CS4)N(C(=O)N5)C(=O)C6=CC=C(C=C6)C(C)(C)C
IUPAC Name: 2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-28-((3aS,4S,6aR)-1-(4-(tert-butyl)benzoyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,8,24-trioxo-6,13,16,19-tetraoxa-3,9,23-triazaoctacosyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C68H96N7O14PS/c1-49(2)75(50(3)4)90(88-39-15-34-69)89-45-56(44-87-68(53-18-11-10-12-19-53,54-26-30-57(81-8)31-27-54)55-28-32-58(82-9)33-29-55)72-63(78)47-86-46-62(77)71-36-17-38-84-41-43-85-42-40-83-37-16-35-70-61(76)21-14-13-20-60-64-59(48-91-60)74(66(80)73-64)65(79)51-22-24-52(25-23-51)67(5,6)7/h10-12,18-19,22-33,49-50,56,59-60,64H,13-17,20-21,35-48H2,1-9H3,(H,70,76)(H,71,77)(H,72,78)(H,73,80)/t56?,59-,60-,64-,90?/m0/s1
Synonyms: 3-Dimethoxytrityloxy-2-(3-((4-t-butylbenzoyl)-biotinyl-3-aminopropyl)-diethyleneglycolyl-propylamido-glycanoylamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite

Amino-Modifier Serinol Phosphoramidite

Description: Amino-Modifier Serinol Phosphoramidite, a chemical reagent synonymous with biomedical synthesis, plays a key role in the modification of oligonucleotides - mercifully, chock-full of amino functionalities. As a potent building block, this product holds potential for therapeutic and diagnostic development, with applications pertaining to the likes of cancer, viral infections, and genetic disorders. Well-renowned for its high purity and stability, it remains a stand-out performer in the realm of gene therapy and all matters nucleic acid drug delivery.
CAT: BRP-00269
CAS: 196297-83-3
Molecular Formula: C51H59N4O8P
Molecular Weight: 887.01
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Storage: Store at -20°C
Boiling Point: 938.0±65.0 °C at 760 mmHg
InChIKey: AYVWOMBHOQDZKA-UHFFFAOYSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)NC(=O)CCNC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
IUPAC Name: 9H-fluoren-9-ylmethyl N-[3-[[1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]amino]-3-oxopropyl]carbamate
InChI: InChI=1S/C51H59N4O8P/c1-36(2)55(37(3)4)64(62-32-14-30-52)63-34-41(54-49(56)29-31-53-50(57)60-35-48-46-19-12-10-17-44(46)45-18-11-13-20-47(45)48)33-61-51(38-15-8-7-9-16-38,39-21-25-42(58-5)26-22-39)40-23-27-43(59-6)28-24-40/h7-13,15-28,36-37,41,48H,14,29,31-35H2,1-6H3,(H,53,57)(H,54,56)
Synonyms: 3-Dimethoxytrityloxy-2-(3-(fluorenylmethoxycarbonylamino)propanamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 9-Oxa-2,6,11-triaza-10-phosphatridecanoic acid, 7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-(2-cyanoethoxy)-12-methyl-11-(1-methylethyl)-5-oxo-, 9H-fluoren-9-ylmethyl ester; 9,11-Dioxa-2,6-diaza-10-phosphatridecanoic acid, 7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-5-oxo-, 9H-fluoren-9-ylmethyl ester; 9H-Fluoren-9-ylmethyl 7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-(2-cyanoethoxy)-12-methyl-11-(1-methylethyl)-5-oxo-9-oxa-2,6,11-triaza-10-phosphatridecanoate

Frequently Asked Questions (FAQ)

What are phosphoramidites used for?

Phosphoramidites are activated monomers used in solid-phase DNA and RNA oligonucleotide synthesis.

What is the difference between DNA and RNA phosphoramidites?

RNA phosphoramidites include additional 2′-hydroxyl protecting groups, making them more sensitive to moisture and handling conditions.

Why is moisture control important for phosphoramidites?

Moisture can cause premature hydrolysis of phosphoramidites, reducing coupling efficiency and synthesis yield.

Can phosphoramidites be used for long oligonucleotide synthesis?

Yes, high-quality phosphoramidites are essential for achieving good yields in long and complex oligonucleotide sequences.

Are modified phosphoramidites available for custom oligos?

Modified and specialty phosphoramidites are commonly used to introduce functional groups or labels into oligonucleotides.

* Only for research. Not suitable for any diagnostic or therapeutic use.

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