Nucleosides - RNA / BOC Sciences

2'-O-Methyluridine

Description: Uridine analog. Used for preparation of antiviral nucleoside derivatives as inhibitors of subgenomic hepatitis C virus RNA replication.

CAT: BRP-00012

CAS: 2140-76-3

Molecular Formula: C10H14N2O6

Molecular Weight: 258.23

Purity: ≥95%

Appearance: White solid

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Storage: Store at 2-8 °C

Density: 1.53±0.1 g/cm³ (Predicted)

Melting Point: 154-156 °C

Symbol: Um

InChIKey: SXUXMRMBWZCMEN-ZOQUXTDFSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)NC2=O)CO)O

IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C10H14N2O6/c1-17-8-7(15)5(4-13)18-9(8)12-3-2-6(14)11-10(12)16/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,9-/m1/s1

Synonyms: 2'-(O-Methyl) Uridine; Uridine, 2'-O-methyl-; O(2')-Methyluridine; 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-O-Methyl-β-D-ribofuranosyl)uracil

Tubercidin

Description: Tubercidin is an adenosine analog with antiviral, antitrypanosomal, and antifungal properties. It inhibits DNA/RNA synthesis and other metabolic processes.

CAT: BRP-00018

CAS: 69-33-0

Molecular Formula: C11H14N4O4

Molecular Weight: 266.25

Purity: ≥98% by HPLC

Appearance: White Crystalline Powder

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Storage: Store at-20°C

Density: 1.90±0.1 g/cm3

Melting Point: 247-248 °C (dec.)

Boiling Point: 648.8±55.0 °C at 760 mmHg

Application: 7-Deaza-adenosine is an adenosine analog.

Shelf Life: As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly

InChIKey: HDZZVAMISRMYHH-KCGFPETGSA-N

Solubility: Soluble in Methanol

CanonicalSMILES: C1=CN(C2=NC=NC(=C21)N)C3C(C(C(O3)CO)O)O

IUPAC Name: (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C11H14N4O4/c12-9-5-1-2-15(10(5)14-4-13-9)11-8(18)7(17)6(3-16)19-11/h1-2,4,6-8,11,16-18H,3H2,(H2,12,13,14)/t6-,7-,8-,11-/m1/s1

Synonyms: 7-Deazaadenosine; Antibiotic XK 101-1; BRN 0038498; 7-Deaza ribo Adenosine; 7-β-D-Ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 4-Amino-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 6-Amino-9-D-ribofuranosyl-7-desazapurine; N7-Deazaadenosine; NQZ-003; NSC 56408; Sparsamycin A; Sparsomycin A; Tubercidine; U 10071

Nicotinamide riboside

Description: Nicotinamide riboside is a form of pyridine nucleoside with a nicotinamide. It is a precursor to NAD+ and a source of vitamin B3. Nicotinamide riboside increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6, and HEK293 cells. It also activates SIRT1 and SIRT3 in vitro.

CAT: BRP-00044

CAS: 1341-23-7

Molecular Formula: C11H15N2O5

Molecular Weight: 255.25

Purity: ≥95% (Contain ~80% food grade dextrin as stabilizer)

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InChIKey: JLEBZPBDRKPWTD-TURQNECASA-O

CanonicalSMILES: C1=CC(=C[N+](=C1)C2C(C(C(O2)CO)O)O)C(=O)N

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium-3-carboxamide

InChI: InChI=1S/C11H14N2O5/c12-10(17)6-2-1-3-13(4-6)11-9(16)8(15)7(5-14)18-11/h1-4,7-9,11,14-16H,5H2,(H-,12,17)/p+1/t7-,8-,9-,11-/m1/s1

Synonyms: Nicotinamide-beta-riboside; Nicotinamide ribonucleoside; N-Ribosylnicotinamide; 3-(Aminocarbonyl)-1-β-D-ribofuranosylpyridinium; Pyridinium, 3-carbamoyl-1-β-D-ribofuranosyl-; 3-Pyridinecarboxamide, 1-β-D-ribosyl-; Nicotinamide ribose; Ribosylnicotinamide

2'-O,4'-C-Methyleneguanosine

Description: 2'-O,4'-C-Methyleneguanosine, a modified nucleoside molecule, has demonstrated effective outcomes in the domain of antiviral therapeutics, exemplifying excellent potential as a therapeutic agent for hepatitis C and West Nile virus infections. Substantiated by its unique mechanism of action- hindering viral RNA polymerase, a critical enzyme necessary for viral replication, it is deemed a highly potent approach for viral inhibition. Furthermore, this particular compound presents an enticing opportunity for its application as an antitumor agent, drawing interest from scientific communities.

CAT: BRP-00068

CAS: 207131-16-6

Molecular Formula: C11H13N5O5

Molecular Weight: 295.25

Purity: ≥95%

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Storage: Store at -20 °C

Density: 2.31±0.1 g/cm3 (Predicted)

InChIKey: OZVMOEUWPMYRQU-JUQFDLSGSA-N

CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=NC4=C3N=C(NC4=O)N)O)CO

IUPAC Name: 2-amino-9-((1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-1,9-dihydro-6H-purin-6-one

InChI: InChI=1S/C11H13N5O5/c12-10-14-7-4(8(19)15-10)13-3-16(7)9-5-6(18)11(1-17,21-9)2-20-5/h3,5-6,9,17-18H,1-2H2,(H3,12,14,15,19)/t5-,6+,9-,11+/m1/s1

Synonyms: LNA-G; 2-amino-9-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-1H-purin-6-one; 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine; 2-Amino-9-[2,5-anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-1,9-dihydro-6H-purin-6-one

3'-O-Methylguanosine

Description: 3'-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, it becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject.

CAT: BRP-00077

CAS: 10300-27-3

Molecular Formula: C11H15N5O5

Molecular Weight: 297.27

Purity: ≥95%

Appearance: White to Off-white Powder to Crystalline Powder

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Storage: Store at 2-8°C

Density: 1.98±0.10 g/cm3

Melting Point: 263-300 °C

Boiling Point: 711.7 °C at 760 mmHg

InChIKey: UYARPHAXAJAZLU-KQYNXXCUSA-N

Solubility: In Vitro:
DMSO : 25 mg/mL(84.10 mM;ultrasonic and warming and heat to 60°C)

CanonicalSMILES: COC1C(OC(C1O)N2C=NC3=C2N=C(NC3=O)N)CO

IUPAC Name: 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C11H15N5O5/c1-20-7-4(2-17)21-10(6(7)18)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1

Synonyms: 3'-(O-Methyl) Guanosine; 3'-O-Methyl-D-guanosine; 3'-O-Methyl guanosine; O3'-methyl-guanosine; 3'-OMe-G; 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl]-3,9-dihydro-6H-purin-6-one

3'-O-(2-Methoxyethyl)guanosine

Description: 3'-O-(2-Methoxyethyl)guanosine is a remarkable modified nucleoside with immense potential in the field of antiviral drug discovery. This exquisite compound takes center stage in targeting viral RNA-dependent RNA polymerases, thus rendering it a powerful weapon in research of respiratory syncytial virus (RSV) and hepatitis C virus (HCV).

CAT: BRP-00078

CAS: 256224-03-0

Molecular Formula: C13H19N5O6

Molecular Weight: 341.32

Purity: ≥95%

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Density: 1.81±0.1 g/cm3

InChIKey: DQZXNLOSGQCAEG-LYECJJOESA-N

CanonicalSMILES: COCCOC1C(OC(C1O)N2C=NC3C2=NC(=N)NC3=O)CO

IUPAC Name: 9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-(2-methoxyethoxy)oxolan-2-yl]-2-imino-5H-purin-6-one

InChI: InChI=1S/C13H19N5O6/c1-22-2-3-23-9-6(4-19)24-12(8(9)20)18-5-15-7-10(18)16-13(14)17-11(7)21/h5-9,12,19-20H,2-4H2,1H3,(H2,14,17,21)/t6-,7?,8-,9-,12-/m1/s1

Synonyms: Guanosine, 3'-O-(2-methoxyethyl)-; 3'-O-MOE-G; 2-Amino-9-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one

2'-O-(2-Methoxyethyl)adenosine

Description: It is a derivative of adenosine that acts as a building block for crosslinking oligonucleotides.

CAT: BRP-00082

CAS: 168427-74-5

Molecular Formula: C13H19N5O5

Molecular Weight: 325.32

Purity: ≥95%

Appearance: White Solid

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Storage: Store at -20°C under inert atmosphere

Density: 1.701±0.1 g/cm3 (Predicted)

Melting Point: 54-59°C

Boiling Point: 639.0±65.0°C (Predicted)

InChIKey: PUDXUJRJLRLJIU-QYVSTXNMSA-N

Solubility: Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: COCCOC1C(C(OC1N2C=NC3=C(N=CN=C32)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)oxolan-3-ol

InChI: InChI=1S/C13H19N5O5/c1-21-2-3-22-10-9(20)7(4-19)23-13(10)18-6-17-8-11(14)15-5-16-12(8)18/h5-7,9-10,13,19-20H,2-4H2,1H3,(H2,14,15,16)/t7-,9-,10-,13-/m1/s1

Synonyms: (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol; Adenosine, 2'-O-(2-methoxyethyl)-; 2'-O-methoxyethyl Adenosine; 2'-O-MOE-A; 2'-O-MOE-Adenosine; 2'-O-MOE-rA

2'-O-(2-Methoxyethyl)guanosine

Description: It is a guanosine derivative as a building block for crosslinking oligonucleotides.

CAT: BRP-00084

CAS: 473278-54-5

Molecular Formula: C13H19N5O6

Molecular Weight: 341.32

Purity: ≥95%

Appearance: White to Off-white Crystalline Powder

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Storage: Store at -20°C

Density: 1.81±0.1 g/cm3 (Predicted)

Boiling Point: 715.0±70.0°C (Predicted)

InChIKey: VORWLCQFVYLMRX-LYECJJOESA-N

CanonicalSMILES: COCCOC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O

IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C13H19N5O6/c1-22-2-3-23-9-8(20)6(4-19)24-12(9)18-5-15-7-10(18)16-13(14)17-11(7)21/h5-9,12,19-20H,2-4H2,1H3,(H2,14,17,21)/t6-,7?,8-,9-,12-/m1/s1

Synonyms: Guanosine, 2'-O-(2-methoxyethyl)-; 2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one; 2'-MOE-rG; 2'-O-Methoxyethyl-guanosine; 2'-O-MOE-rG

5'-O-DMT-uridine

Description: It is used for nucleoside modification and RNA synthesis.

CAT: BRP-00113

CAS: 81246-79-9

Molecular Formula: C30H30N2O8

Molecular Weight: 546.57

Purity: ≥98% by HPLC

Appearance: White Solid

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Storage: Store at 2-8°C

Density: 1.343±0.06 g/cm3(Predicted)

Melting Point: 111-112 °C

InChIKey: PCFSNQYXXACUHM-YULOIDQLSA-N

Solubility: Soluble in Ethyl Acetate

CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=O)NC5=O)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C30H30N2O8/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-24-26(34)27(35)28(40-24)32-17-16-25(33)31-29(32)36/h3-17,24,26-28,34-35H,18H2,1-2H3,(H,31,33,36)/t24-,26-,27-,28-/m1/s1

Synonyms: 5'-DMT Uridine; 5'-O-DMT uridine; 5'-O-(4,4'-Dimethyltrityl)uridine; 5'-O-DMT-D-uridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]uridine; 1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine

Description: N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine, an influential antiviral agent extensively employed in the biomedical sector, showcases remarkable efficacy in combating RNA viral infections. Its valuable contributions lie in its capacity to combat diverse viral strains, thereby enlightening researchers on viral replication processes and fostering the advancement of groundbreaking antiviral treatments.

CAT: BRP-00164

CAS: 110764-74-4

Molecular Formula: C38H37N3O8

Molecular Weight: 663.72

Purity: ≥95%

Appearance: White to Light Yellow Powder

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Storage: Store at -20°C

Density: 1.27±0.1 g/cm3 (Predicted)

InChIKey: WXJKGOQQYUVNQW-YDXJMRNDSA-N

CanonicalSMILES: COC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C38H37N3O8/c1-45-29-18-14-27(15-19-29)38(26-12-8-5-9-13-26,28-16-20-30(46-2)21-17-28)48-24-31-33(42)34(47-3)36(49-31)41-23-22-32(40-37(41)44)39-35(43)25-10-6-4-7-11-25/h4-23,31,33-34,36,42H,24H2,1-3H3,(H,39,40,43,44)/t31-,33-,34-,36-/m1/s1

Synonyms: N4-Bz-DMT-2'-OMe-Cr; 5'-DMT-2'-(O-Methyl) Cytidine (n-bz); 5'-O-DMTr-2'-O-Me-rC(Bz); N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methycytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-methylcytidine; 5'-O-DMT-N4-Benzoyl-2'-O-Methyl-Cytidine; DMT-2'-OMe-Bz-C; 5'-O-[alpha,alpha-Bis(4-methoxyphenyl)benzyl]-N-benzoyl-2'-O-methylcytidine

5'-O-DMT-N2-isobutyrylguanosine

Description: 5'-O-DMT-N2-isobutyrylguanosine is a biomedicine product commonly used in the field of nucleic acid research. This compound is a modified form of guanosine and is often utilized as a substrate to study various enzymatic reactions related to DNA and RNA synthesis. It plays a crucial role in investigating the functions of guanine derivatives, offering insights into potential therapeutic approaches for diseases involving nucleic acid metabolism.

CAT: BRP-00169

CAS: 81246-83-5

Molecular Formula: C35H37N5O8

Molecular Weight: 655.70

Purity: ≥95%

Appearance: Pale Yellow Solid

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Storage: Store at 2-8°C

Density: 1.4±0.1 g/cm3

Melting Point: >153°C

Boiling Point: 892.9±75.0°C at 760 mmHg

InChIKey: SSYBHRGSXXKZQZ-QBVBFOPXSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)O

IUPAC Name: N-(9-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

InChI: InChI=1S/C35H37N5O8/c1-20(2)31(43)38-34-37-30-27(32(44)39-34)36-19-40(30)33-29(42)28(41)26(48-33)18-47-35(21-8-6-5-7-9-21,22-10-14-24(45-3)15-11-22)23-12-16-25(46-4)17-13-23/h5-17,19-20,26,28-29,33,41-42H,18H2,1-4H3,(H2,37,38,39,43,44)/t26-,28-,29-,33-/m1/s1

Synonyms: 5'-DMT-ibu-rG; N2-iso-Butyryl-5'-O-(4,4'-dimethoxytrityl)guanosine; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-guanosine; N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide; 5'-O-DMT-ibu-rG; 5'-DMT Guanosine (n-ibu)

1-MethylpseudoUridine

Description: N1-methyl-pseudoUridine (1-Methylpseudouridine), a methylpseudoUridine, outperforms 5 mC and 5 mC/N1-methyl-pseudoUridine in translation. N1-methyl-pseudoUridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density.

CAT: BRP-00238

CAS: 13860-38-3

Molecular Formula: C10H14N2O6

Molecular Weight: 258.23

Purity: ≥95%

Appearance: White to pale pink powder

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Storage: Storage at 2-8°C

Density: 1.6±0.1 g/cm3

Symbol: m¹Ψ

InChIKey: UVBYMVOUBXYSFV-XUTVFYLZSA-N

CanonicalSMILES: CN1C=C(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpyrimidine-2,4-dione

InChI: InChI=1S/C10H14N2O6/c1-12-2-4(9(16)11-10(12)17)8-7(15)6(14)5(3-13)18-8/h2,5-8,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,8+/m1/s1

Synonyms: N1-Methylpseudouridine; 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-b-D-ribofuranosyl-; (-)-1-Methyl-5-(β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; Antibiotic U-50228; U-50228; 1-N-Me-pseudouridine; (1S)-1,4-anhydro-1-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol; Uracil, 1-methyl-5-b-D-ribofuranosyl-

β-pseudoUridine

Description: An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation. Studies suggest that Beta-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes.

CAT: BRP-00315

CAS: 1445-07-4

Molecular Formula: C9H12N2O6

Molecular Weight: 244.20

Purity: 98%

Appearance: White to Off-white Solid

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Storage: Store at 2-8°C

Density: 1.641±0.06 g/cm3 (Predicted)

Melting Point: 212-214°C

Boiling Point: 598.4±60.0 °C at 760 mmHg

Symbol: Ψ

InChIKey: PTJWIQPHWPFNBW-GBNDHIKLSA-N

Solubility: Soluble in Methanol (Very Slightly, Heated), Water (Slightly, Sonicated, Heated)

CanonicalSMILES: C1=C(C(=O)NC(=O)N1)C2C(C(C(O2)CO)O)O

IUPAC Name: 5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-pyrimidine-2,4-dione

InChI: InChI=1S/C9H12N2O6/c12-2-4-5(13)6(14)7(17-4)3-1-10-9(16)11-8(3)15/h1,4-7,12-14H,2H2,(H2,10,11,15,16)/t4-,5-,6-,7+/m1/s1

Synonyms: Pseudouridine; ψ-Uridine; 5-(β-D-Ribofuranosyl)uracil; b-pseudoUridine; 5-β-D-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione; 5-Ribosyluracil; NSC 162405; Pseudouridine C; β-D-Pseudouridine; pseudo-Uridine; Pseudouracil; Pseudouridine; β-Pseudouridine; 5-((2S,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine

Description: 3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine is a biochemical compound widely used in the biomedical industry. This product is utilized in the development of antiviral drugs and therapies for treating viral infections such as hepatitis and HIV. Its unique properties make it a valuable tool for researchers studying nucleotide modifications and their impact on RNA function.

CAT: BRP-00361

CAS: 171268-84-1

Molecular Formula: C16H28N2O6Si

Molecular Weight: 372.49

Purity: ≥95%

Appearance: White to Off-white Powder

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5 g	$498	In stock

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Storage: Store at 2-8°C

Density: 1.20±0.1 g/cm3 (Predicted)

InChIKey: VWMFRWSCFRRALN-FMKGYKFTSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1OC)N2C=CC(=O)NC2=O)CO

IUPAC Name: 1-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C16H28N2O6Si/c1-16(2,3)25(5,6)24-12-10(9-19)23-14(13(12)22-4)18-8-7-11(20)17-15(18)21/h7-8,10,12-14,19H,9H2,1-6H3,(H,17,20,21)/t10-,12-,13-,14-/m1/s1

Synonyms: Uridine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-methyl-; 2'-O-Methyl-3'-O-(tert-butyldimethylsilyl)uridine; 1-((2R,3R,4R,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 3'-O-TBDMS-2'-OMe-U; 3'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-2'-O-methyluridine; 3'-TBDMS-2'-O-Me-rU

3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine

Description: 3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine is a highly complex and perplexing compound, playing a pivotal role in combatting viruses. Notably, it showcases exceptional selectivity and efficacy against viral replication and tumor proliferation, thereby emerging as an indispensable asset in the development of antiviral medicines and anticancer researchs.

CAT: BRP-00366

CAS: 1445379-59-8

Molecular Formula: C15H25FN2O5Si

Molecular Weight: 360.45

Purity: ≥95%

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1 g	$399	In stock

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Storage: Store at 2-8 °C

Density: 1.2±0.1 g/cm3

InChIKey: KKWGVZHEXOEALO-OJAKKHQRSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1F)N2C=CC(=O)NC2=O)CO

IUPAC Name: 1-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-3-fluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C15H25FN2O5Si/c1-15(2,3)24(4,5)23-12-9(8-19)22-13(11(12)16)18-7-6-10(20)17-14(18)21/h6-7,9,11-13,19H,8H2,1-5H3,(H,17,20,21)/t9-,11-,12-,13-/m1/s1

Synonyms: 1-((2R,3R,4R,5R)-4-((tert-Butyldimethylsilyl)oxy)-3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-Deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluorouridine; Uridine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-; 3'-O-TBDMS-2'-F-dU

5'-O-DMT-2'-O-methylcytidine

Description: 5'-O-DMT-2'-O-methylcytidine is a biomedicine research product used for the treatment of viral infections, cancer, and neurological disorders. It acts as an antiviral and anticancer agent by inhibiting viral replication and tumor growth, respectively. Additionally, it also has neuroprotective properties that help in treating neurological disorders.

CAT: BRP-01632

CAS: 103285-21-8

Molecular Formula: C31H33N3O7

Molecular Weight: 559.62

Purity: ≥98% by HPLC

Appearance: White to Off-white Powder

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Storage: Store at 2-8°C

Density: 1.3±0.1 g/cm3

Boiling Point: 729.7±70.0°C at 760 mmHg

InChIKey: JUECLTUXFCGWTO-YXINZVNLSA-N

CanonicalSMILES: COC1C(C(OC1N2C=CC(=NC2=O)N)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C31H33N3O7/c1-37-23-13-9-21(10-14-23)31(20-7-5-4-6-8-20,22-11-15-24(38-2)16-12-22)40-19-25-27(35)28(39-3)29(41-25)34-18-17-26(32)33-30(34)36/h4-18,25,27-29,35H,19H2,1-3H3,(H2,32,33,36)/t25-,27-,28-,29-/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine; DMT-2'-OMe-Cr; 5'-O-DMT-2'-O-methyl-D-cytidine; 5'-O-DMT-2'-OMe-rC; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylcytidine

2',3'-Di-O-acetyluridine

Description: 2',3'-Di-O-acetyluridine, a compound extensively utilized in the biomedical domain, exhibits remarkable potential in therapeutics. Notably, it has exhibited substantial efficacy in mitigating diverse ailments including neurological disorders and liver diseases. Research activities are currently underway to unravel the intricate mechanisms of its action and identify precise drug targets.

CAT: BRP-01692

CAS: 29108-90-5

Molecular Formula: C13H16N2O8

Molecular Weight: 328.27

Purity: ≥95%

Appearance: White Crystalline Powder

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1 g	$199	In stock

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Storage: Store at -20°C

Density: 1.49±0.10 g/cm3

Melting Point: 142-143 °C

InChIKey: BUHMZKLSFGZBHP-HJQYOEGKSA-N

CanonicalSMILES: CC(=O)OC1C(OC(C1OC(=O)C)N2C=CC(=O)NC2=O)CO

IUPAC Name: [(2R,3R,4R,5R)-4-acetyloxy-5-(2,4-dioxopyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] acetate

InChI: InChI=1S/C13H16N2O8/c1-6(17)21-10-8(5-16)23-12(11(10)22-7(2)18)15-4-3-9(19)14-13(15)20/h3-4,8,10-12,16H,5H2,1-2H3,(H,14,19,20)/t8-,10-,11-,12-/m1/s1

Synonyms: 2',3'-Diacetyl Uridine; 2'-O,3'-O-Diacetyluridine; 2',3'-Di-O-acetyl-D-uridine; Uridine, 2',3'-diacetate; (2R,3R,4R,5R)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl diacetate; 2',3'-O,O-diacetyluridine

L-Guanosine

Description: L-Guanosine is a remarkable nucleoside widely utilized in exploring intricate neurological disorders, including Alzheimer's disease and dementia. Furthermore, L-Guanosine's pivotal role in RNA synthesis has propelled its prominence in the realm of antiviral drug development, specifically in the context of studying pernicious RNA viruses, such as hepatitis C.

CAT: BRP-01729

CAS: 26578-09-6

Molecular Formula: C10H13N5O5

Molecular Weight: 283.24

Purity: ≥97% by HPLC

Appearance: White to Off-white Crystalline Powder

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10 mg	$298	In stock

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Storage: Store at 2-8°C

Density: 2.25±0.1 g/cm3 (Predicted)

Boiling Point: 775.9±70.0°C (Predicted)

InChIKey: NYHBQMYGNKIUIF-GIMIYPNGSA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(NC2=O)N

IUPAC Name: 2-amino-9-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m0/s1

Synonyms: Beta-L-ribo Guanosine; 9-(b-L-Ribofuranosyl)guanine; L-rG; 2-amino-9-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-L-ribofuranosyl-; 2-Amino-9-(β-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one; 2-Amino-1,9-dihydro-9-β-L-ribofuranosyl-6H-purin-6-one

5-Methoxyuridine

Description: 5-Methoxyuridine is an analog of Uridine and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist.

CAT: BRP-01759

CAS: 35542-01-9

Molecular Formula: C10H14N2O7

Molecular Weight: 274.23

Purity: ≥95%

Appearance: White to Off-white Powder

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50 mg	$239	In stock

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Storage: Store at 2-8 °C

Density: 1.65±0.1 g/cm3 (Predicted)

Melting Point: 217-218°C

Symbol: mo⁵U

InChIKey: ZXIATBNUWJBBGT-JXOAFFINSA-N

Solubility: Soluble in Water (50 mg/mL, clear, colorless)

CanonicalSMILES: COC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxypyrimidine-2,4-dione

InChI: InChI=1S/C10H14N2O7/c1-18-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)19-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1

Synonyms: Uridine, 5-methoxy-; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H,3H)-dione; 5-OMe-Ur

2-Amino-6-chloropurine-9-(2'-O-methyl)riboside

Description: 2-Amino-6-chloropurine-9-(2'-O-methyl)riboside is a remarkable biomedical entity, diligently confronting the pernicious wrath of herpes simplex virus and varicella-zoster virus, rendering them futile through the inhibition of viral DNA synthesis and replication.

CAT: BRP-01768

CAS: 194034-59-8

Molecular Formula: C11H14ClN5O4

Molecular Weight: 315.71

Purity: ≥95%

Appearance: White Solid

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25 mg	$298	In stock

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Storage: Store at 2-8 °C

Density: 1.94±0.1 g/cm3

Boiling Point: 675.6±65.0°C at 760 mmHg

InChIKey: MDXXTTIZSFJMOD-KQYNXXCUSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(N=C3Cl)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol

InChI: InChI=1S/C11H14ClN5O4/c1-20-7-6(19)4(2-18)21-10(7)17-3-14-5-8(12)15-11(13)16-9(5)17/h3-4,6-7,10,18-19H,2H2,1H3,(H2,13,15,16)/t4-,6-,7-,10-/m1/s1

Synonyms: 6-Chloro-2'-O-methylguanosine; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; 2-Amino-6-chloro-9-(2'-O-methyl-beta-D-ribofuranosyl)-9H-purine; 6-Chloro-9-(2-O-methyl-β-D-ribofuranosyl)-9H-purin-2-amine; 2'-O-Methyl-2-amino-6-chloropurine riboside