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2'-Modified Nucleosides
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2'-O-Methyluridine
Description: Uridine analog. Used for preparation of antiviral nucleoside derivatives as inhibitors of subgenomic hepatitis C virus RNA replication.
CAT: BRP-00012
CAS: 2140-76-3
MF: C10H14N2O6
MF: 258.23
Purity: ≥95%
Appearance: White solid
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 25 g | $239 | In stock |
Storage: Store at 2-8 °C
Density: 1.53±0.1 g/cm3 (Predicted)
Melting Point: 154-156 °C
Symbol: Um
InChIKey: SXUXMRMBWZCMEN-ZOQUXTDFSA-N
Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)
CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)NC2=O)CO)O
IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C10H14N2O6/c1-17-8-7(15)5(4-13)18-9(8)12-3-2-6(14)11-10(12)16/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,16)/t5-,7-,8-,9-/m1/s1
Synonyms: 2'-(O-Methyl) Uridine; Uridine, 2'-O-methyl-; O(2')-Methyluridine; 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-O-Methyl-β-D-ribofuranosyl)uracil
Tubercidin
Description: Tubercidin is an adenosine analog with antiviral, antitrypanosomal, and antifungal properties. It inhibits DNA/RNA synthesis and other metabolic processes.
CAT: BRP-00018
CAS: 69-33-0
MF: C11H14N4O4
MF: 266.25
Purity: ≥98% by HPLC
Appearance: White Crystalline Powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 500 mg | $439 | In stock |
Storage: Store at-20°C
Density: 1.90±0.1 g/cm3
Melting Point: 247-248 °C (dec.)
Boiling Point: 648.8±55.0 °C at 760 mmHg
Application: 7-Deaza-adenosine is an adenosine analog.
Shelf Life: As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
InChIKey: HDZZVAMISRMYHH-KCGFPETGSA-N
Solubility: Soluble in Methanol
CanonicalSMILES: C1=CN(C2=NC=NC(=C21)N)C3C(C(C(O3)CO)O)O
IUPAC Name: (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChI: InChI=1S/C11H14N4O4/c12-9-5-1-2-15(10(5)14-4-13-9)11-8(18)7(17)6(3-16)19-11/h1-2,4,6-8,11,16-18H,3H2,(H2,12,13,14)/t6-,7-,8-,11-/m1/s1
Synonyms: 7-Deazaadenosine; Antibiotic XK 101-1; BRN 0038498; 7-Deaza ribo Adenosine; 7-β-D-Ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 4-Amino-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 6-Amino-9-D-ribofuranosyl-7-desazapurine; N7-Deazaadenosine; NQZ-003; NSC 56408; Sparsamycin A; Sparsomycin A; Tubercidine; U 10071
Nicotinamide riboside
Description: Nicotinamide riboside is a form of pyridine nucleoside with a nicotinamide. It is a precursor to NAD+ and a source of vitamin B3. Nicotinamide riboside increases intracellular and mitochondrial NAD+ content in C2C12, Hepa1.6, and HEK293 cells. It also activates SIRT1 and SIRT3 in vitro.
CAT: BRP-00044
CAS: 1341-23-7
MF: C11H15N2O5
MF: 255.25
Purity: ≥95% (Contain ~80% food grade dextrin as stabilizer)
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 5 g | $298 | In stock |
InChIKey: JLEBZPBDRKPWTD-TURQNECASA-O
CanonicalSMILES: C1=CC(=C[N+](=C1)C2C(C(C(O2)CO)O)O)C(=O)N
IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium-3-carboxamide
InChI: InChI=1S/C11H14N2O5/c12-10(17)6-2-1-3-13(4-6)11-9(16)8(15)7(5-14)18-11/h1-4,7-9,11,14-16H,5H2,(H-,12,17)/p+1/t7-,8-,9-,11-/m1/s1
Synonyms: Nicotinamide-beta-riboside; Nicotinamide ribonucleoside; N-Ribosylnicotinamide; 3-(Aminocarbonyl)-1-β-D-ribofuranosylpyridinium; Pyridinium, 3-carbamoyl-1-β-D-ribofuranosyl-; 3-Pyridinecarboxamide, 1-β-D-ribosyl-; Nicotinamide ribose; Ribosylnicotinamide
2'-O,4'-C-Methyleneguanosine
Description: 2'-O,4'-C-Methyleneguanosine, a modified nucleoside molecule, has demonstrated effective outcomes in the domain of antiviral therapeutics, exemplifying excellent potential as a therapeutic agent for hepatitis C and West Nile virus infections. Substantiated by its unique mechanism of action- hindering viral RNA polymerase, a critical enzyme necessary for viral replication, it is deemed a highly potent approach for viral inhibition. Furthermore, this particular compound presents an enticing opportunity for its application as an antitumor agent, drawing interest from scientific communities.
CAT: BRP-00068
CAS: 207131-16-6
MF: C11H13N5O5
MF: 295.25
Purity: ≥95%
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $1099 | In stock |
Storage: Store at -20 °C
Density: 2.31±0.1 g/cm3 (Predicted)
InChIKey: OZVMOEUWPMYRQU-JUQFDLSGSA-N
CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=NC4=C3N=C(NC4=O)N)O)CO
IUPAC Name: 2-amino-9-((1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-1,9-dihydro-6H-purin-6-one
InChI: InChI=1S/C11H13N5O5/c12-10-14-7-4(8(19)15-10)13-3-16(7)9-5-6(18)11(1-17,21-9)2-20-5/h3,5-6,9,17-18H,1-2H2,(H3,12,14,15,19)/t5-,6+,9-,11+/m1/s1
Synonyms: LNA-G; 2-amino-9-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-1H-purin-6-one; 1-(2'-O-4-C-Methylene-b-D-ribofuranosyl)guanine; 2-Amino-9-[2,5-anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-1,9-dihydro-6H-purin-6-one
3'-O-Methylguanosine
Description: 3'-O-Methylguanosine is an endogenous methylated nucleoside found in human fluids. Methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls. DNA hypermethylation is a common finding in malignant cells and has been explored as a therapeutic target for hypomethylating agents. When chemical bonds to DNA, it becomes damaged and proper and complete replication cannot occur to make the normal intended cell. A DNA adduct is an abnormal piece of DNA covalently-bonded to a cancer-causing chemical. This has shown to be the start of a cancerous cell, or carcinogenesis. DNA adducts in scientific experiments are used as bio-markers and as such are themselves measured to reflect quantitatively, for comparison, the amount of cancer in the subject.
CAT: BRP-00077
CAS: 10300-27-3
MF: C11H15N5O5
MF: 297.27
Purity: ≥95%
Appearance: White to Off-white Powder to Crystalline Powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $168 | In stock |
Storage: Store at 2-8°C
Density: 1.98±0.10 g/cm3
Melting Point: 263-300 °C
Boiling Point: 711.7 °C at 760 mmHg
InChIKey: UYARPHAXAJAZLU-KQYNXXCUSA-N
Solubility: In Vitro:
DMSO : 25 mg/mL(84.10 mM;ultrasonic and warming and heat to 60°C)
DMSO : 25 mg/mL(84.10 mM;ultrasonic and warming and heat to 60°C)
CanonicalSMILES: COC1C(OC(C1O)N2C=NC3=C2N=C(NC3=O)N)CO
IUPAC Name: 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-1H-purin-6-one
InChI: InChI=1S/C11H15N5O5/c1-20-7-4(2-17)21-10(6(7)18)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1
Synonyms: 3'-(O-Methyl) Guanosine; 3'-O-Methyl-D-guanosine; 3'-O-Methyl guanosine; O3'-methyl-guanosine; 3'-OMe-G; 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl]-3,9-dihydro-6H-purin-6-one
3'-O-(2-Methoxyethyl)guanosine
Description: 3'-O-(2-Methoxyethyl)guanosine is a remarkable modified nucleoside with immense potential in the field of antiviral drug discovery. This exquisite compound takes center stage in targeting viral RNA-dependent RNA polymerases, thus rendering it a powerful weapon in research of respiratory syncytial virus (RSV) and hepatitis C virus (HCV).
CAT: BRP-00078
CAS: 256224-03-0
MF: C13H19N5O6
MF: 341.32
Purity: ≥95%
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 2 g | $1980 | In stock |
Density: 1.81±0.1 g/cm3
InChIKey: DQZXNLOSGQCAEG-LYECJJOESA-N
CanonicalSMILES: COCCOC1C(OC(C1O)N2C=NC3C2=NC(=N)NC3=O)CO
IUPAC Name: 9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-(2-methoxyethoxy)oxolan-2-yl]-2-imino-5H-purin-6-one
InChI: InChI=1S/C13H19N5O6/c1-22-2-3-23-9-6(4-19)24-12(8(9)20)18-5-15-7-10(18)16-13(14)17-11(7)21/h5-9,12,19-20H,2-4H2,1H3,(H2,14,17,21)/t6-,7?,8-,9-,12-/m1/s1
Synonyms: Guanosine, 3'-O-(2-methoxyethyl)-; 3'-O-MOE-G; 2-Amino-9-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one
2'-O-(2-Methoxyethyl)adenosine
Description: It is a derivative of adenosine that acts as a building block for crosslinking oligonucleotides.
CAT: BRP-00082
CAS: 168427-74-5
MF: C13H19N5O5
MF: 325.32
Purity: ≥95%
Appearance: White Solid
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 1 g | $259 | In stock |
Storage: Store at -20°C under inert atmosphere
Density: 1.701±0.1 g/cm3 (Predicted)
Melting Point: 54-59°C
Boiling Point: 639.0±65.0°C (Predicted)
InChIKey: PUDXUJRJLRLJIU-QYVSTXNMSA-N
Solubility: Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
CanonicalSMILES: COCCOC1C(C(OC1N2C=NC3=C(N=CN=C32)N)CO)O
IUPAC Name: (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)oxolan-3-ol
InChI: InChI=1S/C13H19N5O5/c1-21-2-3-22-10-9(20)7(4-19)23-13(10)18-6-17-8-11(14)15-5-16-12(8)18/h5-7,9-10,13,19-20H,2-4H2,1H3,(H2,14,15,16)/t7-,9-,10-,13-/m1/s1
Synonyms: (2R,3R,4R,5R)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol; Adenosine, 2'-O-(2-methoxyethyl)-; 2'-O-methoxyethyl Adenosine; 2'-O-MOE-A; 2'-O-MOE-Adenosine; 2'-O-MOE-rA
2'-O-(2-Methoxyethyl)guanosine
Description: It is a guanosine derivative as a building block for crosslinking oligonucleotides.
CAT: BRP-00084
CAS: 473278-54-5
MF: C13H19N5O6
MF: 341.32
Purity: ≥95%
Appearance: White to Off-white Crystalline Powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 1 g | $176 | In stock |
Storage: Store at -20°C
Density: 1.81±0.1 g/cm3 (Predicted)
Boiling Point: 715.0±70.0°C (Predicted)
InChIKey: VORWLCQFVYLMRX-LYECJJOESA-N
CanonicalSMILES: COCCOC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O
IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-1H-purin-6-one
InChI: InChI=1S/C13H19N5O6/c1-22-2-3-23-9-8(20)6(4-19)24-12(9)18-5-15-7-10(18)16-13(14)17-11(7)21/h5-9,12,19-20H,2-4H2,1H3,(H2,14,17,21)/t6-,7?,8-,9-,12-/m1/s1
Synonyms: Guanosine, 2'-O-(2-methoxyethyl)-; 2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one; 2'-MOE-rG; 2'-O-Methoxyethyl-guanosine; 2'-O-MOE-rG
5'-O-DMT-uridine
Description: It is used for nucleoside modification and RNA synthesis.
CAT: BRP-00113
CAS: 81246-79-9
MF: C30H30N2O8
MF: 546.57
Purity: ≥98% by HPLC
Appearance: White Solid
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 100 g | $899 | In stock |
Storage: Store at 2-8°C
Density: 1.343±0.06 g/cm3(Predicted)
Melting Point: 111-112 °C
InChIKey: PCFSNQYXXACUHM-YULOIDQLSA-N
Solubility: Soluble in Ethyl Acetate
CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=O)NC5=O)O)O
IUPAC Name: 1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C30H30N2O8/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-24-26(34)27(35)28(40-24)32-17-16-25(33)31-29(32)36/h3-17,24,26-28,34-35H,18H2,1-2H3,(H,31,33,36)/t24-,26-,27-,28-/m1/s1
Synonyms: 5'-DMT Uridine; 5'-O-DMT uridine; 5'-O-(4,4'-Dimethyltrityl)uridine; 5'-O-DMT-D-uridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]uridine; 1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine
Description: N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine, an influential antiviral agent extensively employed in the biomedical sector, showcases remarkable efficacy in combating RNA viral infections. Its valuable contributions lie in its capacity to combat diverse viral strains, thereby enlightening researchers on viral replication processes and fostering the advancement of groundbreaking antiviral treatments.
CAT: BRP-00164
CAS: 110764-74-4
MF: C38H37N3O8
MF: 663.72
Purity: ≥95%
Appearance: White to Light Yellow Powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 5 g | $469 | In stock | |
| 10 g | $788 | In stock |
Storage: Store at -20°C
Density: 1.27±0.1 g/cm3 (Predicted)
InChIKey: WXJKGOQQYUVNQW-YDXJMRNDSA-N
CanonicalSMILES: COC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C38H37N3O8/c1-45-29-18-14-27(15-19-29)38(26-12-8-5-9-13-26,28-16-20-30(46-2)21-17-28)48-24-31-33(42)34(47-3)36(49-31)41-23-22-32(40-37(41)44)39-35(43)25-10-6-4-7-11-25/h4-23,31,33-34,36,42H,24H2,1-3H3,(H,39,40,43,44)/t31-,33-,34-,36-/m1/s1
Synonyms: N4-Bz-DMT-2'-OMe-Cr; 5'-DMT-2'-(O-Methyl) Cytidine (n-bz); 5'-O-DMTr-2'-O-Me-rC(Bz); N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methycytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-methylcytidine; 5'-O-DMT-N4-Benzoyl-2'-O-Methyl-Cytidine; DMT-2'-OMe-Bz-C; 5'-O-[alpha,alpha-Bis(4-methoxyphenyl)benzyl]-N-benzoyl-2'-O-methylcytidine
5'-O-DMT-N2-isobutyrylguanosine
Description: 5'-O-DMT-N2-isobutyrylguanosine is a biomedicine product commonly used in the field of nucleic acid research. This compound is a modified form of guanosine and is often utilized as a substrate to study various enzymatic reactions related to DNA and RNA synthesis. It plays a crucial role in investigating the functions of guanine derivatives, offering insights into potential therapeutic approaches for diseases involving nucleic acid metabolism.
CAT: BRP-00169
CAS: 81246-83-5
MF: C35H37N5O8
MF: 655.70
Purity: ≥95%
Appearance: Pale Yellow Solid
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 25 g | $348 | In stock | |
| 100 g | $629 | In stock |
Storage: Store at 2-8°C
Density: 1.4±0.1 g/cm3
Melting Point: >153°C
Boiling Point: 892.9±75.0°C at 760 mmHg
InChIKey: SSYBHRGSXXKZQZ-QBVBFOPXSA-N
Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)O
IUPAC Name: N-(9-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
InChI: InChI=1S/C35H37N5O8/c1-20(2)31(43)38-34-37-30-27(32(44)39-34)36-19-40(30)33-29(42)28(41)26(48-33)18-47-35(21-8-6-5-7-9-21,22-10-14-24(45-3)15-11-22)23-12-16-25(46-4)17-13-23/h5-17,19-20,26,28-29,33,41-42H,18H2,1-4H3,(H2,37,38,39,43,44)/t26-,28-,29-,33-/m1/s1
Synonyms: 5'-DMT-ibu-rG; N2-iso-Butyryl-5'-O-(4,4'-dimethoxytrityl)guanosine; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-guanosine; N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide; 5'-O-DMT-ibu-rG; 5'-DMT Guanosine (n-ibu)
1-MethylpseudoUridine
Description: N1-methyl-pseudoUridine (1-Methylpseudouridine), a methylpseudoUridine, outperforms 5 mC and 5 mC/N1-methyl-pseudoUridine in translation. N1-methyl-pseudoUridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density.
CAT: BRP-00238
CAS: 13860-38-3
MF: C10H14N2O6
MF: 258.23
Purity: ≥95%
Appearance: White to pale pink powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 1 g | $367 | In stock |
Storage: Storage at 2-8°C
Density: 1.6±0.1 g/cm3
Symbol: m1Ψ
InChIKey: UVBYMVOUBXYSFV-XUTVFYLZSA-N
CanonicalSMILES: CN1C=C(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
IUPAC Name: 5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpyrimidine-2,4-dione
InChI: InChI=1S/C10H14N2O6/c1-12-2-4(9(16)11-10(12)17)8-7(15)6(14)5(3-13)18-8/h2,5-8,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,8+/m1/s1
Synonyms: N1-Methylpseudouridine; 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-b-D-ribofuranosyl-; (-)-1-Methyl-5-(β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; Antibiotic U-50228; U-50228; 1-N-Me-pseudouridine; (1S)-1,4-anhydro-1-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol; Uracil, 1-methyl-5-b-D-ribofuranosyl-
β-pseudoUridine
Description: An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation. Studies suggest that Beta-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes.
CAT: BRP-00315
CAS: 1445-07-4
MF: C9H12N2O6
MF: 244.20
Purity: 98%
Appearance: White to Off-white Solid
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 5 g | $198 | In stock |
Storage: Store at 2-8°C
Density: 1.641±0.06 g/cm3 (Predicted)
Melting Point: 212-214°C
Boiling Point: 598.4±60.0 °C at 760 mmHg
Symbol: Ψ
InChIKey: PTJWIQPHWPFNBW-GBNDHIKLSA-N
Solubility: Soluble in Methanol (Very Slightly, Heated), Water (Slightly, Sonicated, Heated)
CanonicalSMILES: C1=C(C(=O)NC(=O)N1)C2C(C(C(O2)CO)O)O
IUPAC Name: 5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-pyrimidine-2,4-dione
InChI: InChI=1S/C9H12N2O6/c12-2-4-5(13)6(14)7(17-4)3-1-10-9(16)11-8(3)15/h1,4-7,12-14H,2H2,(H2,10,11,15,16)/t4-,5-,6-,7+/m1/s1
Synonyms: Pseudouridine; ψ-Uridine; 5-(β-D-Ribofuranosyl)uracil; b-pseudoUridine; 5-β-D-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione; 5-Ribosyluracil; NSC 162405; Pseudouridine C; β-D-Pseudouridine; pseudo-Uridine; Pseudouracil; Pseudouridine; β-Pseudouridine; 5-((2S,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine
Description: 3'-O-(t-Butyldimethylsilyl)-2'-O-methyluridine is a biochemical compound widely used in the biomedical industry. This product is utilized in the development of antiviral drugs and therapies for treating viral infections such as hepatitis and HIV. Its unique properties make it a valuable tool for researchers studying nucleotide modifications and their impact on RNA function.
CAT: BRP-00361
CAS: 171268-84-1
MF: C16H28N2O6Si
MF: 372.49
Purity: ≥95%
Appearance: White to Off-white Powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 5 g | $498 | In stock |
Storage: Store at 2-8°C
Density: 1.20±0.1 g/cm3 (Predicted)
InChIKey: VWMFRWSCFRRALN-FMKGYKFTSA-N
CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1OC)N2C=CC(=O)NC2=O)CO
IUPAC Name: 1-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C16H28N2O6Si/c1-16(2,3)25(5,6)24-12-10(9-19)23-14(13(12)22-4)18-8-7-11(20)17-15(18)21/h7-8,10,12-14,19H,9H2,1-6H3,(H,17,20,21)/t10-,12-,13-,14-/m1/s1
Synonyms: Uridine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-O-methyl-; 2'-O-Methyl-3'-O-(tert-butyldimethylsilyl)uridine; 1-((2R,3R,4R,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 3'-O-TBDMS-2'-OMe-U; 3'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-2'-O-methyluridine; 3'-TBDMS-2'-O-Me-rU
3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine
Description: 3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine is a highly complex and perplexing compound, playing a pivotal role in combatting viruses. Notably, it showcases exceptional selectivity and efficacy against viral replication and tumor proliferation, thereby emerging as an indispensable asset in the development of antiviral medicines and anticancer researchs.
CAT: BRP-00366
CAS: 1445379-59-8
MF: C15H25FN2O5Si
MF: 360.45
Purity: ≥95%
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 1 g | $399 | In stock |
Storage: Store at 2-8 °C
Density: 1.2±0.1 g/cm3
InChIKey: KKWGVZHEXOEALO-OJAKKHQRSA-N
CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1F)N2C=CC(=O)NC2=O)CO
IUPAC Name: 1-[(2R,3R,4R,5R)-4-[tert-butyl(dimethyl)silyl]oxy-3-fluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C15H25FN2O5Si/c1-15(2,3)24(4,5)23-12-9(8-19)22-13(11(12)16)18-7-6-10(20)17-14(18)21/h6-7,9,11-13,19H,8H2,1-5H3,(H,17,20,21)/t9-,11-,12-,13-/m1/s1
Synonyms: 1-((2R,3R,4R,5R)-4-((tert-Butyldimethylsilyl)oxy)-3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-Deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluorouridine; Uridine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-; 3'-O-TBDMS-2'-F-dU
5'-O-DMT-2'-O-methylcytidine
Description: 5'-O-DMT-2'-O-methylcytidine is a biomedicine research product used for the treatment of viral infections, cancer, and neurological disorders. It acts as an antiviral and anticancer agent by inhibiting viral replication and tumor growth, respectively. Additionally, it also has neuroprotective properties that help in treating neurological disorders.
CAT: BRP-01632
CAS: 103285-21-8
MF: C31H33N3O7
MF: 559.62
Purity: ≥98% by HPLC
Appearance: White to Off-white Powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at 2-8°C
Density: 1.3±0.1 g/cm3
Boiling Point: 729.7±70.0°C at 760 mmHg
InChIKey: JUECLTUXFCGWTO-YXINZVNLSA-N
CanonicalSMILES: COC1C(C(OC1N2C=CC(=NC2=O)N)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O
IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidin-2-one
InChI: InChI=1S/C31H33N3O7/c1-37-23-13-9-21(10-14-23)31(20-7-5-4-6-8-20,22-11-15-24(38-2)16-12-22)40-19-25-27(35)28(39-3)29(41-25)34-18-17-26(32)33-30(34)36/h4-18,25,27-29,35H,19H2,1-3H3,(H2,32,33,36)/t25-,27-,28-,29-/m1/s1
Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine; DMT-2'-OMe-Cr; 5'-O-DMT-2'-O-methyl-D-cytidine; 5'-O-DMT-2'-OMe-rC; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylcytidine
2',3'-Di-O-acetyluridine
Description: 2',3'-Di-O-acetyluridine, a compound extensively utilized in the biomedical domain, exhibits remarkable potential in therapeutics. Notably, it has exhibited substantial efficacy in mitigating diverse ailments including neurological disorders and liver diseases. Research activities are currently underway to unravel the intricate mechanisms of its action and identify precise drug targets.
CAT: BRP-01692
CAS: 29108-90-5
MF: C13H16N2O8
MF: 328.27
Purity: ≥95%
Appearance: White Crystalline Powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 1 g | $199 | In stock |
Storage: Store at -20°C
Density: 1.49±0.10 g/cm3
Melting Point: 142-143 °C
InChIKey: BUHMZKLSFGZBHP-HJQYOEGKSA-N
CanonicalSMILES: CC(=O)OC1C(OC(C1OC(=O)C)N2C=CC(=O)NC2=O)CO
IUPAC Name: [(2R,3R,4R,5R)-4-acetyloxy-5-(2,4-dioxopyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] acetate
InChI: InChI=1S/C13H16N2O8/c1-6(17)21-10-8(5-16)23-12(11(10)22-7(2)18)15-4-3-9(19)14-13(15)20/h3-4,8,10-12,16H,5H2,1-2H3,(H,14,19,20)/t8-,10-,11-,12-/m1/s1
Synonyms: 2',3'-Diacetyl Uridine; 2'-O,3'-O-Diacetyluridine; 2',3'-Di-O-acetyl-D-uridine; Uridine, 2',3'-diacetate; (2R,3R,4R,5R)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl diacetate; 2',3'-O,O-diacetyluridine
L-Guanosine
Description: L-Guanosine is a remarkable nucleoside widely utilized in exploring intricate neurological disorders, including Alzheimer's disease and dementia. Furthermore, L-Guanosine's pivotal role in RNA synthesis has propelled its prominence in the realm of antiviral drug development, specifically in the context of studying pernicious RNA viruses, such as hepatitis C.
CAT: BRP-01729
CAS: 26578-09-6
MF: C10H13N5O5
MF: 283.24
Purity: ≥97% by HPLC
Appearance: White to Off-white Crystalline Powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $298 | In stock |
Storage: Store at 2-8°C
Density: 2.25±0.1 g/cm3 (Predicted)
Boiling Point: 775.9±70.0°C (Predicted)
InChIKey: NYHBQMYGNKIUIF-GIMIYPNGSA-N
CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(NC2=O)N
IUPAC Name: 2-amino-9-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
InChI: InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m0/s1
Synonyms: Beta-L-ribo Guanosine; 9-(b-L-Ribofuranosyl)guanine; L-rG; 2-amino-9-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-L-ribofuranosyl-; 2-Amino-9-(β-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one; 2-Amino-1,9-dihydro-9-β-L-ribofuranosyl-6H-purin-6-one
5-Methoxyuridine
Description: 5-Methoxyuridine is an analog of Uridine and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist.
CAT: BRP-01759
CAS: 35542-01-9
MF: C10H14N2O7
MF: 274.23
Purity: ≥95%
Appearance: White to Off-white Powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $239 | In stock |
Storage: Store at 2-8 °C
Density: 1.65±0.1 g/cm3 (Predicted)
Melting Point: 217-218°C
Symbol: mo5U
InChIKey: ZXIATBNUWJBBGT-JXOAFFINSA-N
Solubility: Soluble in Water (50 mg/mL, clear, colorless)
CanonicalSMILES: COC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxypyrimidine-2,4-dione
InChI: InChI=1S/C10H14N2O7/c1-18-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)19-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
Synonyms: Uridine, 5-methoxy-; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H,3H)-dione; 5-OMe-Ur
2-Amino-6-chloropurine-9-(2'-O-methyl)riboside
Description: 2-Amino-6-chloropurine-9-(2'-O-methyl)riboside is a remarkable biomedical entity, diligently confronting the pernicious wrath of herpes simplex virus and varicella-zoster virus, rendering them futile through the inhibition of viral DNA synthesis and replication.
CAT: BRP-01768
CAS: 194034-59-8
MF: C11H14ClN5O4
MF: 315.71
Purity: ≥95%
Appearance: White Solid
| Size | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $298 | In stock |
Storage: Store at 2-8 °C
Density: 1.94±0.1 g/cm3
Boiling Point: 675.6±65.0°C at 760 mmHg
InChIKey: MDXXTTIZSFJMOD-KQYNXXCUSA-N
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(N=C3Cl)N)CO)O
IUPAC Name: (2R,3R,4R,5R)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol
InChI: InChI=1S/C11H14ClN5O4/c1-20-7-6(19)4(2-18)21-10(7)17-3-14-5-8(12)15-11(13)16-9(5)17/h3-4,6-7,10,18-19H,2H2,1H3,(H2,13,15,16)/t4-,6-,7-,10-/m1/s1
Synonyms: 6-Chloro-2'-O-methylguanosine; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; 2-Amino-6-chloro-9-(2'-O-methyl-beta-D-ribofuranosyl)-9H-purine; 6-Chloro-9-(2-O-methyl-β-D-ribofuranosyl)-9H-purin-2-amine; 2'-O-Methyl-2-amino-6-chloropurine riboside
