What are nucleosides used for?

Nucleosides are base molecules used as starting materials for synthesizing nucleotides and phosphoramidites.

What is the difference between nucleosides and nucleotides?

Nucleosides lack phosphate groups, while nucleotides contain one or more phosphates required for enzymatic reactions.

Are nucleosides used directly in enzymatic reactions?

Nucleosides are typically chemically modified before being used in enzymatic workflows.

Can nucleosides be chemically modified?

Yes, modified nucleosides are widely used to introduce structural or functional changes in nucleic acids.

Why is nucleoside purity important?

High purity ensures correct downstream synthesis of nucleotides and phosphoramidites with predictable performance.

Nucleosides - RNA / BOC Sciences

5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine

Description: 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine, an intriguing bioactive compound, has garnered attention in the biomedical industry for its potential antiviral prowess. Demonstrating commendable efficacy in impeding viral replication, it holds promise in combatting viral ailments such as herpes and hepatitis. However, the precise workings of this compound remain enigmatic, warranting further exploration in the realm of antiviral drug development.

CAT: BRP-00106

CAS: 251647-50-4

Molecular Formula: C38H43N5O9

Molecular Weight: 713.78

Purity: ≥95%

Appearance: White to Pale Yellow Crystalline Powder

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Storage: Store at RT

Density: 1.33±0.1 g/cm3(Predicted)

Melting Point: 112.5-126.6 °C

InChIKey: XDLPRZLZAFJSMA-BEGXHNNXSA-N

Solubility: Soluble in Hexane

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OCCOC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C38H43N5O9/c1-23(2)34(45)41-37-40-33-30(35(46)42-37)39-22-43(33)36-32(50-20-19-47-3)31(44)29(52-36)21-51-38(24-9-7-6-8-10-24,25-11-15-27(48-4)16-12-25)26-13-17-28(49-5)18-14-26/h6-18,22-23,29,31-32,36,44H,19-21H2,1-5H3,(H2,40,41,42,45,46)/t29-,31-,32-,36-/m1/s1

Synonyms: N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 2'-O-MOE-5'-O-DMT-G(iBu); 5'-O-DMT-2'-O-MOE-N2-iBu-rG; 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine

2'-O-(2-Methoxyethyl)-5-methylcytidine

Description: 2'-O-(2-Methoxyethyl)-5-methylcytidine is an intrinsic antiviral compound, garnering substantial interest within the biomedical field for the research of its efficacy against RNA viruses. By impeding viral replication, this compound presenting a formidable prospect for the formulation of unprecedented antiviral interventions.

CAT: BRP-00107

CAS: 244105-55-3

Molecular Formula: C13H21N3O6

Molecular Weight: 315.32

Purity: ≥98% by HPLC

Appearance: White to off-white crystalline powder

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Storage: Store at -20°C under inert atmosphere

Density: 1.52 g/cm3

Melting Point: >70°C (dec.)

Boiling Point: 536.5±60.0 °C(Predicted)

InChIKey: GUEIFVRYWPOXHJ-DNRKLUKYSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)OCCOC

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidin-2-one

InChI: InChI=1S/C13H21N3O6/c1-7-5-16(13(19)15-11(7)14)12-10(21-4-3-20-2)9(18)8(6-17)22-12/h5,8-10,12,17-18H,3-4,6H2,1-2H3,(H2,14,15,19)/t8-,9-,10-,12-/m1/s1

Synonyms: 5-Me-2'-O-MOE-C; 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one; 5-Methyl-2'-O-methoxyethyl-cytidine; 5-Me-2'-O-MOE-Cr

N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-5-methylcytidine

Description: N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-5-methylcytidine, a potent biomedicine, holds significant promise as an antiviral therapeutic agent.

CAT: BRP-00108

CAS: 182496-01-1

Molecular Formula: C41H43N3O9

Molecular Weight: 721.79

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: Store at -20°C

Density: 1.26±0.1 g/cm3

InChIKey: BYSCLUAIKFEFAH-LZURGKRNSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OCCOC

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C41H43N3O9/c1-27-25-44(40(47)43-37(27)42-38(46)28-11-7-5-8-12-28)39-36(51-24-23-48-2)35(45)34(53-39)26-52-41(29-13-9-6-10-14-29,30-15-19-32(49-3)20-16-30)31-17-21-33(50-4)22-18-31/h5-22,25,34-36,39,45H,23-24,26H2,1-4H3,(H,42,43,46,47)/t34-,35-,36-,39-/m1/s1

Synonyms: N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-(2-methoxyethyl)-5-methylcytidine; N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine; N4-Benzoyl-2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methylcytidine; 2'-O-MOE-5'-O-DMT-5-Me-C(Bz); 5'-O-DMT-2'-O-MOE-5-Me-C(Bz)

2'-O-(2-Methoxyethy)-5-methyluridine

Description: 2'-O-(2-Methoxyethy)-5-methyluridine is a nucleoside analog renowned in the biomedical realm, unveiling its potent antiviral attributes. I

CAT: BRP-00109

CAS: 163759-49-7

Molecular Formula: C13H20N2O7

Molecular Weight: 316.31

Purity: ≥95%

Appearance: White to Off-white Crystalline Powder

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Storage: Store at -20°C under inert atmosphere

Density: 1.41 g/cm3

Melting Point: 115.5-116.5 °C

InChIKey: NEVQCHBUJFYGQO-DNRKLUKYSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)OCCOC

IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C13H20N2O7/c1-7-5-15(13(19)14-11(7)18)12-10(21-4-3-20-2)9(17)8(6-16)22-12/h5,8-10,12,16-17H,3-4,6H2,1-2H3,(H,14,18,19)/t8-,9-,10-,12-/m1/s1

Synonyms: 2'-O-MOE-5-Methyluridine; 2'-O-Methoxyethyl-thymidine; 2'-O-MOE-T; 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5-Me-2'-O-MOE U; 5-Me-2'-O-MOE Uridine

5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine

Description: 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a potent compound used in research of RNA viruses, particularly hepatitis C virus and picornaviruses. This nucleoside analogue inhibits viral replication by interfering with viral RNA research and development.

CAT: BRP-00110

CAS: 163759-50-0

Molecular Formula: C34H38N2O9

Molecular Weight: 618.67

Purity: ≥98% by HPLC

Appearance: Off-white Crystalline Powder

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Storage: Store at RT

Density: 1.32 g/cm3

InChIKey: WIPCVBQXKBWNRC-PBAMLIMUSA-N

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OCCOC

IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C34H38N2O9/c1-22-20-36(33(39)35-31(22)38)32-30(43-19-18-40-2)29(37)28(45-32)21-44-34(23-8-6-5-7-9-23,24-10-14-26(41-3)15-11-24)25-12-16-27(42-4)17-13-25/h5-17,20,28-30,32,37H,18-19,21H2,1-4H3,(H,35,38,39)/t28-,29-,30-,32-/m1/s1

Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methyluridine; 5'-O-DMT-2'-O-MOE-5-methyluridine; 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyluridine; 5'-O-DMT-2'-O-MOE-5-MeU

2,2'-Anhydrouridine

Description: 2,2'-Anhydrouridine is a modified nucleoside that lacks a hydroxyl group at the 2' position of the ribose ring. It is commonly found in transfer RNA (tRNA) and plays a role in stabilizing the tRNA structure. This modification is important for proper tRNA function as it helps maintain the overall stability and folding of the molecule. 2,2'-Anhydrouridine is also known to be involved in the recognition and binding of tRNA to the ribosome during protein synthesis.

CAT: BRP-00111

CAS: 3736-77-4

Molecular Formula: C9H10N2O5

Molecular Weight: 226.19

Purity: ≥95%

Appearance: White to off-white (Solid)

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Storage: Store at RT

Density: 2.01±0.1 g/cm3

Melting Point: 234-235 °C

Boiling Point: 456.3±55.0 °C at 760 mmHg

Flash Point: 229.8±31.5 °C

InChIKey: UUGITDASWNOAGG-CCXZUQQUSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: C1=CN2C3C(C(C(O3)CO)O)OC2=NC1=O

IUPAC Name: (2R,4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one

InChI: InChI=1S/C9H10N2O5/c12-3-4-6(14)7-8(15-4)11-2-1-5(13)10-9(11)16-7/h1-2,4,6-8,12,14H,3H2/t4-,6-,7+,8-/m1/s1

Synonyms: 2,2'-Anhydro-b-D-arabinofuranosyl uracil; O-2,2'-Cyclouridine; 2,2'-Anhydro-D-uridine; 2,2'-Anhydro Uridine; (2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-2-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-on; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-, [2R-(2α,3β,3aβ,9aβ)]-; 2,2'-Anhydro(1-β-D-arabinofuranosyl)uracil; 2,2'-Anhydro-N1-(β-D-arabinofuranosyl)uracil; 2,2'-Anhydrouridine; 2,2'-O-Cyclouridine; NSC 157148; O2,2'-Anhydrouridine; O2,2'-Cyclouridine; β-D-2',2-O-Cycloarabinouridine

2,2'-Anhydro-5-methyluridine

Description: 2,2'-Anhydro-5-methyluridine is a chemically modified nucleoside derivative of uridine, where the 2' hydroxyl group of the ribose is linked to the 2-position of the uracil ring, forming an anhydro bond. Additionally, the uracil base is methylated at the 5-position. This modification alters the nucleoside's properties, making it useful in biochemical and pharmacological research, particularly in studies focused on nucleic acid chemistry and potential therapeutic applications.

CAT: BRP-00112

CAS: 22423-26-3

Molecular Formula: C10H12N2O5

Molecular Weight: 240.21

Purity: ≥95%

Appearance: White to off-white crystalline powder

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Storage: Store at RT

Density: 1.88±0.1 g/cm³ (Predicted)

Melting Point: 217.0-221.0 °C

Boiling Point: 452.0±55.0 °C (Predicted)

InChIKey: WLLOAUCNUMYOQI-JAGXHNFQSA-N

CanonicalSMILES: CC1=CN2C3C(C(C(O3)CO)O)OC2=NC1=O

IUPAC Name: (2R,4R,5R,6S)-5-hydroxy-4-(hydroxymethyl)-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one

InChI: InChI=1S/C10H12N2O5/c1-4-2-12-9-7(6(14)5(3-13)16-9)17-10(12)11-8(4)15/h2,5-7,9,13-14H,3H2,1H3/t5-,6-,7+,9-/m1/s1

Synonyms: O-2,2'-Anhydro-5-methyluridine; 2,2'-Anhydro-5-methyl-D-uridine; 2,2'-Anhydro-(1-b-D-arabinofuranosyl)-5-methyluracil; 2,2'-Anhydro-D-thymidine; 2,2'-Anhydro-5-methyluridine; (2R,3R,3aS,9aR)-3-Hydroxy-2-(hydroxymethyl)-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one; 2,2'-Anhydro-1-beta-arabinofuranosylthymine

5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine

Description: 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is an exceptionally powerful antiviral compound, possessing an unparalleled propensity to combat the scourges perpetuated by viral entities. It acts as a formidable weapon against the replication machineries employed by diverse RNA viruses, such as influenza, hepatitis C and respiratory syncytial virus (RSV).

CAT: BRP-00114

CAS: 182496-00-0

Molecular Formula: C34H39N3O8

Molecular Weight: 617.69

Purity: ≥95% by HPLC

Appearance: White to Off-white Solid

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Storage: Store at 2-8 °C

Density: 1.27±0.1 g/cm3 (Predicted)

Boiling Point: 762.6±70.0 °C at 760 mmHg

InChIKey: LYKTVJJXZQTNPK-PBAMLIMUSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OCCOC

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-5-methylpyrimidin-2-one

InChI: InChI=1S/C34H39N3O8/c1-22-20-37(33(39)36-31(22)35)32-30(43-19-18-40-2)29(38)28(45-32)21-44-34(23-8-6-5-7-9-23,24-10-14-26(41-3)15-11-24)25-12-16-27(42-4)17-13-25/h5-17,20,28-30,32,38H,18-19,21H2,1-4H3,(H2,35,36,39)/t28-,29-,30-,32-/m1/s1

Synonyms: 4-Amino-1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one; 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine; 2'-O-methoxyethyl-5'-O-dimethoxytrityl-5-methylcytidine; 2'-O-MOE-5'-O-DMT-5-Me-C; 5'-O-DMT-2'-O-MOE-5-MeC

2,2'-Anhydro-5'-O-DMT-5-methyluridine

Description: 2,2'-Anhydro-5'-O-DMT-5-methyluridine is a remarkable biomedicine agent having shown substantial efficacy in research of combating viral infections and specific neoplastic conditions. Unveiling its antiviral prowess against RNA viruses, this compound showcases a promising proclivity for impeding malignant tumor expansion.

CAT: BRP-00115

CAS: 817623-11-3

Molecular Formula: C31H30N2O7

Molecular Weight: 542.58

Purity: ≥95%

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Storage: Store at 2-8 °C

Density: 1.3±0.1 g/cm3

Boiling Point: 692.9±65.0°C at 760 mmHg

InChIKey: BQEQCEZNLIKSSH-CITHKVLSSA-N

CanonicalSMILES: CC1=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OC2=NC1=O

IUPAC Name: (2R,4R,5R,6S)-4-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-hydroxy-11-methyl-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one

InChI: InChI=1S/C31H30N2O7/c1-19-17-33-29-27(40-30(33)32-28(19)35)26(34)25(39-29)18-38-31(20-7-5-4-6-8-20,21-9-13-23(36-2)14-10-21)22-11-15-24(37-3)16-12-22/h4-17,25-27,29,34H,18H2,1-3H3/t25-,26-,27+,29-/m1/s1

Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-5-methyl-2,2'-anhydro-b-D-arabinofuranosyluracil; 5'-O-(4,4'-Dimethoxytrityl)-5-methyl-2,2'-anhydro-D-uridine; 5'-DMTr-2,2'-anhydrothymidine; (2R,3R,3aS,9aR)-2-{[Bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-hydroxy-7-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one

5'-O-(4,4'-Dimethoxytrityl)-2,2'-anhydro-D-uridine

Description: 5'-O-(4,4'-Dimethoxytrityl)-2,2'-anhydro-D-uridine, a multifaceted compound extensively employed in the field of biomedicine, exhibits utmost significance. Its pivotal involvement lies within the synthesis of pharmaceutical nucleoside analogs, specifically for combating viral infections such as HIV and hepatitis.

CAT: BRP-00116

CAS: 173170-12-2

Molecular Formula: C30H28N2O7

Molecular Weight: 528.55

Purity: ≥95%

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Density: 1.4±0.1 g/cm3

Boiling Point: 688.2±65.0°C at 760 mmHg

InChIKey: OEIRLWHCGAICDW-AOGFTHLWSA-N

CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C5C(O4)N6C=CC(=O)N=C6O5)O

IUPAC Name: (2R,4R,5R,6S)-4-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-hydroxy-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-10-one

InChI: InChI=1S/C30H28N2O7/c1-35-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(36-2)15-11-21)37-18-24-26(34)27-28(38-24)32-17-16-25(33)31-29(32)39-27/h3-17,24,26-28,34H,18H2,1-2H3/t24-,26-,27+,28-/m1/s1

Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2,2'-anhydro-b-D-arabinofuranosyluracil; (2R,3R,3aS,9aR)-2-{[bis(4-methoxyphenyl)(phenyl)methoxy]methyl}-3-hydroxy-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-6-one; 2,2'-Anhydro-5'-O-DMT-uridine; 2,2'-Anhydro-5'-O-(4,4'-dimethoxytrityl)uridine; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-2,3,3a,9a-tetrahydro-3-hydroxy-, [2R-(2α,3β,3aβ,9aβ)]-

S-Adenosyl-L-Methionine

Description: S-adenosyl-l-methionine (SAMe) is a naturally occurring substance which is a major source of methyl groups in the brain. The efficacy of SAMe in treating depressive syndromes and disorders is superior to that of placebo and comparable to that of standard tricyclic antidepressants. Since SAMe is a naturally occurring compound with relatively few side effects, it is a potentially important treatment for depression. S-adenosylmethionine (SAMe) is a dietary supplement used in the management of osteoarthritis (OA) symptoms. Studies evaluating SAMe in the management of OA have been limited to Non Steroidal Anti-inflammatory Drugs (NSAIDs) for comparison. The present study compares the effectiveness of SAMe to a cyclooxygenase-2 (COX-2) inhibitor (celecoxib) for pain control, functional improvement and to decrease side effects in people with osteoarthritis of the knee. It also acts as a PDE4B inhibitor.
Nutritional supplement in health care products.

CAT: BRP-00119

CAS: 29908-03-0

Molecular Formula: C15H22N6O5S

Molecular Weight: 398.44

Purity: 98%

Appearance: White to Off-White Powder

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Storage: Store at -20 °C

Application: Ingredient of health care products.

InChIKey: MEFKEPWMEQBLKI-AIRLBKTGSA-N

CanonicalSMILES: C[S+](CCC(C(=O)[O-])N)CC1C(C(C(O1)N2C=NC3=C2N=CN=C3N)O)O

IUPAC Name: (2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl-methylsulfonio]butanoate

InChI: InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/t7-,8+,10+,11+,14+,27?/m0/s1

Synonyms: S-Adenosylmethionine; Ademetionine; AdoMet; MSI-195; MSI 195; MSI195; SAMe; S-Adenosyl-L-methionine; L-S-Adenosylmethionine; S-Adenosyl methionine; Adenosine, 5'-[(L-3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxy-, hydroxide, inner salt; Active methionine; Adenosyl-L-methionine; Donamet; S Amet; SAH (S-Adenosylmethionine); SAM; SAM (S-Adenosyl methionine); Transmetil

5-Fluoro Cytidine

Description: 5-Fluoro Cytidine is a modified nucleoside that contains a fluorine atom at the 5th position of the cytidine molecule. It is a synthetic compound that has shown potential therapeutic effects in the treatment of certain types of cancer. 5-Fluoro Cytidine works by disrupting the process of RNA replication and inhibiting cell growth. It is currently being studied in clinical trials for its anti-cancer properties. 5-Fluoropyrimidine nucleotides as RNA structure probe using 19F-NMR spectroscopy.

CAT: BRP-00127

CAS: 2341-22-2

Molecular Formula: C9H12FN3O5

Molecular Weight: 261.21

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at -20°C

Density: 1.98±0.1 g/cm3 (Predicted)

Melting Point: 183-185°C

Boiling Point: 511.4±60.0°C (Predicted)

InChIKey: STRZQWQNZQMHQR-UAKXSSHOSA-N

Solubility: Soluble in Methanol (Slightly, Heated), Water (Slightly)

CanonicalSMILES: C1=C(C(=NC(=O)N1C2C(C(C(O2)CO)O)O)N)F

IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoropyrimidin-2-one

InChI: InChI=1S/C9H12FN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1

Synonyms: 5-Fluorocytidine; 5F-C; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidin-2(1H)-one; 4-Amino-5-fluor-1-(β-D-ribofuranosyl)pyrimidin-2(1H)-one; L-β-Ribofuranosyl-5-fluoro-cytosine

3-Deazaadenosine

Description: 3-Deazaadenosine (3-DZA) is an inhibitor of SAH hydrolase (Ki = 3.9 μM). 3-Deazaadenosine is a modified form of the nucleoside adenosine, where a nitrogen atom in the purine ring is replaced with a carbon atom. This modification results in the compound lacking the ability to form hydrogen bonds with complementary nucleotides, making it useful in studying the role of hydrogen bonding in nucleic acid structure and function. 3-Deazaadenosine has been investigated for its potential therapeutic applications, such as in the treatment of viral infections and cancer. It is also used as a biochemical tool in research to study RNA interactions and enzymatic mechanisms.

CAT: BRP-00145

CAS: 6736-58-9

Molecular Formula: C11H14N4O4

Molecular Weight: 266.26

Purity: ≥97% by HPLC

Appearance: Crystalline Solid

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Storage: Store at -20°C

Density: 1.90±0.1 g/cm3 at 20°C, 760 Torr

Melting Point: 222-224°C

Boiling Point: 665.7±65.0°C (Predicted)

Flash Point: 356.4±34.3 °C

InChIKey: DBZQFUNLCALWDY-PNHWDRBUSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=CN=C(C2=C1N(C=N2)C3C(C(C(O3)CO)O)O)N

IUPAC Name: (2R,3R,4S,5R)-2-(4-aminoimidazo[4,5-c]pyridin-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C11H14N4O4/c12-10-7-5(1-2-13-10)15(4-14-7)11-9(18)8(17)6(3-16)19-11/h1-2,4,6,8-9,11,16-18H,3H2,(H2,12,13)/t6-,8-,9-,11-/m1/s1

Synonyms: Deaza-Ado; (2R,3R,4S,5R)-2-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 3-Deaza-rA; 1-(beta-D-ribofuranosyl)-1H-imidazo[4,5-c]pyridin-4-amine; 4-Amino-1-(β-D-ribofuranosyl)-1H-imidazo(4,5)-pyridine

Zeatin riboside

Description: A well-known, highly active stimulant of cell divisions in plant tissue cultures.

CAT: BRP-00146

CAS: 6025-53-2

Molecular Formula: C15H21N5O5

Molecular Weight: 351.36

Purity: 98%

Appearance: White to Pale Yellow Solid

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Storage: Store at -20°C (under dark)

Density: 1.65±0.1 g/cm3

Melting Point: 178-182°C

Boiling Point: 731.8±70.0°C at 760 mmHg

Application: Plant Growth Regulators

InChIKey: GOSWTRUMMSCNCW-HNNGNKQASA-N

Solubility: Soluble in acetic acid (50 mg/mL), DMSO (Slightly), Methanol (Slightly, Sonicated)

CanonicalSMILES: CC(=CCNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O)CO

IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-[[(E)-4-hydroxy-3-methylbut-2-enyl]amino]purin-9-yl]oxolane-3,4-diol

InChI: InChI=1S/C15H21N5O5/c1-8(4-21)2-3-16-13-10-14(18-6-17-13)20(7-19-10)15-12(24)11(23)9(5-22)25-15/h2,6-7,9,11-12,15,21-24H,3-5H2,1H3,(H,16,17,18)/b8-2+/t9-,11-,12-,15-/m1/s1

Synonyms: Adenosine, N-[(2E)-4-hydroxy-3-methyl-2-buten-1-yl]-; Adenosine, N-(4-hydroxy-3-methyl-2-butenyl)-, (E)-; Adenosine, N-[(2E)-4-hydroxy-3-methyl-2-butenyl]-; N-[(2E)-4-Hydroxy-3-methyl-2-buten-1-yl]adenosine; 6-[(E)-4-Hydroxy-3-methylbut-2-enylamino]-9-β-D-ribofuranosylpurine; 6-(4-Hydroxy-3-methyl-trans-2-butenylamino)-9-β-D-ribofuranosylpurine; 9-Ribosyl-trans-zeatin; 9-β-D-Ribofuranosylzeatin; MB 804; N6-(4-Hydroxy-3-methylbut-2-trans-enyl)adenosine; N6-(trans-4-Hydroxy-3-methylbut-2-enyl)adenosine; Ribosyl-trans-zeatin; Ribosylzeatin; trans-Zeatin 9-riboside; trans-Zeatin riboside; Zeatin 9-riboside; Zeatin 9-β-ribonucleoside; Zeatin ribonucleoside; Zeatin-9-β-D-ribofuranoside

Related CAS: 7286-65-9 (Deleted CAS) ; 50816-91-6 (Deleted CAS)

2'-O-tert-Butyldimethylsilyl-5-methyluridine

Description: 2'-O-tert-Butyldimethylsilyl-5-methyluridine standing as an essential entity wielded within the biomedical realm to orchestrate the research and development of nucleoside analogs. Rendering itself instrumental in crafting antiviral medications and providing a foundational cornerstone for tackling an assortment of viral afflictions, this compound exhibiting indomitably consequential characteristics that have propelled it towards the forefront of pharmaceutical research and development.

CAT: BRP-00147

CAS: 922508-26-7

Molecular Formula: C16H28N2O6Si

Molecular Weight: 372.49

Purity: ≥97% by HPLC

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Density: 1.23±0.1 g/cm3

Melting Point: 97-100 °C

InChIKey: PWAAFDSCYLYFMA-HKUMRIAESA-N

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O[Si](C)(C)C(C)(C)C

IUPAC Name: 1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C16H28N2O6Si/c1-9-7-18(15(22)17-13(9)21)14-12(11(20)10(8-19)23-14)24-25(5,6)16(2,3)4/h7,10-12,14,19-20H,8H2,1-6H3,(H,17,21,22)/t10-,11-,12-,14-/m1/s1

Synonyms: 2'-TBDMS-5-Me-rU; 2'-O-[(1,1-Dimethylethyl)dimethylsilyl]-5-methyluridine; 2'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-5-methyluridine

2'-O-tert-butyldimethylsilyl-N4-Benzoyl-cytidine

Description: 2'-O-tert-butyldimethylsilyl-N4-Benzoyl-cytidine is a complex and multifunctional nucleoside analog extensively used in pharmaceutical applications to counter cytidine-sensitive viruses, including hepatitis B and C infections. The compound serves as a significant precursor for the synthesis of modified RNA-based therapies that have promising curative effects for genetic disorders and cancer treatments. Its diverse chemical properties make it an essential and indispensable agent for investigating various antiviral mechanisms that could pave the way for novel and innovative drug discovery.

CAT: BRP-00148

CAS: 185398-21-4

Molecular Formula: C22H31N3O6Si

Molecular Weight: 461.58

Purity: ≥97% by HPLC

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Density: 1.161±0.06 g/cm3

Boiling Point: 608.6±65.0 °C at 760 mmHg

InChIKey: VVBIKBICTSKFIO-DLVXIWMQSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)CO)O

IUPAC Name: N-[1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C22H31N3O6Si/c1-22(2,3)32(4,5)31-18-17(27)15(13-26)30-20(18)25-12-11-16(24-21(25)29)23-19(28)14-9-7-6-8-10-14/h6-12,15,17-18,20,26-27H,13H2,1-5H3,(H,23,24,28,29)/t15-,17-,18-,20-/m1/s1

Synonyms: 2'-TBDMS-Bz-rC; N4-Benzoyl-2'-O-tert-butyldimethylsilylcytidine; N-Benzoyl-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]cytidine; Cytidine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-

2'-O-tert-Butyldimethylsilyluridine

Description: 2'-O-tert-Butyldimethylsilyluridine, an indispensable compound within the biomedical field, serves as a pivotal synthetic intermediate for nucleoside analogues. Notably, it assumes a vital function in the production of antiviral medications, specifically targeting the eradication of hepatitis B and C viral infections. Given its distinct structural and inherent characteristics, this compound assumes an indispensable role in the intricate processes of drug discovery and development.

CAT: BRP-00149

CAS: 54925-71-2

Molecular Formula: C15H26N2O6Si

Molecular Weight: 358.46

Purity: ≥97% by HPLC

Appearance: White to Off-white Crystalline Powder

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Storage: Store at RT

Density: 1.25±0.1 g/cm3

Melting Point: 192-194 °C

InChIKey: AYQZFVZTNUOLCQ-OJAKKHQRSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=CC(=O)NC2=O)CO)O

IUPAC Name: 1-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C15H26N2O6Si/c1-15(2,3)24(4,5)23-12-11(20)9(8-18)22-13(12)17-7-6-10(19)16-14(17)21/h6-7,9,11-13,18,20H,8H2,1-5H3,(H,16,19,21)/t9-,11-,12-,13-/m1/s1

Synonyms: 2'-TBDMS-rU; Uridine, 2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 2'-O-[Dimethyl(2-methyl-2-propanyl)silyl]uridine; 2'-O-[(1,1-Dimethylethyl)dimethylsilyl]uridine

N4-Acetyl-5'-O-tert-butyldimethylsilylcytidine

Description: N4-Acetyl-5'-O-tert-butyldimethylsilylcytidine is utilized as a key component for research and development related to antiviral drugs. It plays a role in the research of various viral infections, supporting the design and development of innovative antiviral therapies.

CAT: BRP-00150

CAS: 119794-51-3

Molecular Formula: C17H29N3O6Si

Molecular Weight: 399.51

Purity: 97%

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Density: 1.28±0.1 g/cm3

InChIKey: WVZROKQICURVJD-NMFUWQPSSA-N

CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO[Si](C)(C)C(C)(C)C)O)O

IUPAC Name: N-[1-[(2R,3R,4S,5R)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-3,4-dihydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C17H29N3O6Si/c1-10(21)18-12-7-8-20(16(24)19-12)15-14(23)13(22)11(26-15)9-25-27(5,6)17(2,3)4/h7-8,11,13-15,22-23H,9H2,1-6H3,(H,18,19,21,24)/t11-,13-,14-,15-/m1/s1

Synonyms: 5'-TBDMS-Ac-rC; Cytidine, N-acetyl-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-; N-Acetyl-5'-O-[(1,1-dimethylethyl)dimethylsilyl]cytidine; 5'-O-tert-Butyldimethylsilyl-N4-acetyl-cytidine

N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine

Description: N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine, a remarkable and potent biomedicine, stands as a beacon of hope in the fight against viral infections, including hepatitis C and HIV. Through meticulous investigation, scientists have unveiled its profound antiviral prowess, effectively hindering viral replication. By skillfully targeting specific viral enzymes, it adeptly curtails viral load while bolstering the body's immune response.

CAT: BRP-00151

CAS: 69504-07-0

Molecular Formula: C23H31N5O5Si

Molecular Weight: 485.61

Purity: ≥97% by HPLC

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Density: 1.33±0.1 g/cm3 (Predicted)

InChIKey: XZQPQOSSEMTXOW-UVLLPENVSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O

IUPAC Name: N-[9-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C23H31N5O5Si/c1-23(2,3)34(4,5)33-18-17(30)15(11-29)32-22(18)28-13-26-16-19(24-12-25-20(16)28)27-21(31)14-9-7-6-8-10-14/h6-10,12-13,15,17-18,22,29-30H,11H2,1-5H3,(H,24,25,27,31)/t15-,17-,18-,22-/m1/s1

Synonyms: 2'-TBDMS-Bz-rA; 2'-O-tert-butyldimethylsilyl-N6-Benzoyl-adenosine; N-Benzoyl-2'-O-(tert-butyldimethylsilyl)adenosine; Adenosine, N-benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; N-Benzoyl-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]adenosine; N-Benzoyl-2'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosine; 2'-O-tert-Butyldimethylsilyl-N-benzoyladenosine; N6-Benzoyl-2'-O-(tert-butyldimethylsilyl)adenosine

6-Chloro-9-(β-D-ribofuranosyl)purine

Description: 6-Chloro-9-(β-D-ribofuranosyl)purine, a potent pharmaceutical compound, finds its application in combating chemotherapy-induced emesis and radiation sickness. Its remarkable antiviral activity thwarts diverse viral infections by effectively impeding viral replication. Additionally, this product serves as an invaluable nucleoside analog for cutting-edge research pertaining to nucleic acids and nucleotide metabolism.

CAT: BRP-00152

CAS: 2004-06-0

Molecular Formula: C10H11ClN4O4

Molecular Weight: 286.67

Purity: 97%

Appearance: Yellow to Green Powder