What are nucleosides used for?

Nucleosides are base molecules used as starting materials for synthesizing nucleotides and phosphoramidites.

What is the difference between nucleosides and nucleotides?

Nucleosides lack phosphate groups, while nucleotides contain one or more phosphates required for enzymatic reactions.

Are nucleosides used directly in enzymatic reactions?

Nucleosides are typically chemically modified before being used in enzymatic workflows.

Can nucleosides be chemically modified?

Yes, modified nucleosides are widely used to introduce structural or functional changes in nucleic acids.

Why is nucleoside purity important?

High purity ensures correct downstream synthesis of nucleotides and phosphoramidites with predictable performance.

Nucleosides - RNA / BOC Sciences

2',3',5'-triacetyl-5-azacytidine

Description: 5-Azacytidine is an inhibitor of DNA methyltransferase, potentially serving to reverse epigenetic changes. 2',3',5'-triacetyl-5-Azacytidine is a prodrug form of 5-azacytidine.

CAT: BRP-00198

CAS: 10302-78-0

Molecular Formula: C14H18N4O8

Molecular Weight: 370.31

Purity: ≥98% by HPLC

Appearance: Crystalline Solid

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Storage: Store at 2-8°C

Density: 1.60±0.1 g/cm3 (Predicted)

Boiling Point: 497.3±55.0 °C at 760 mmHg

InChIKey: OTQJVHISAFFLMA-DDHJBXDOSA-N

Solubility: Soluble in DMF (30 mg/ml), DMSO (30 mg/ml), Ethanol (30 mg/ml), PBS (pH 7.2, 10 mg/ml)

CanonicalSMILES: CC(=O)OCC1C(C(C(O1)N2C=NC(=NC2=O)N)OC(=O)C)OC(=O)C

IUPAC Name: [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(4-amino-2-oxo-1,3,5-triazin-1-yl)oxolan-2-yl]methyl acetate

InChI: InChI=1S/C14H18N4O8/c1-6(19)23-4-9-10(24-7(2)20)11(25-8(3)21)12(26-9)18-5-16-13(15)17-14(18)22/h5,9-12H,4H2,1-3H3,(H2,15,17,22)/t9-,10-,11-,12-/m1/s1

Synonyms: 5-Azacytidine 2',3',5'-O-triacetate; 2',3',5'-Triacetate-4-amino-1-β-D-ribofuranosyl-s-triazin-2(1H)-one; 2',3',5'-Tri-O-acetyl-5-Azacitidine; NSC 291930; 4-Amino-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one

Cytarabine

Description: Arabinofuranosyl-cytosine (ara-C) is an inhibitor of DNA synthesis used as an antineoplastic and antiviral. It is a chemotherapy agent used to treat cancers of white blood cells like acute myeloid leukemia (AML) and non-Hodgkin lymphoma.

CAT: BRP-00199

CAS: 147-94-4

Molecular Formula: C9H13N3O5

Molecular Weight: 243.22

Purity: ≥95%

Appearance: White crystalline powder

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Storage: Store at -20 °C

Density: 1.89±0.1 g/cm3

Melting Point: >210 °C (dec.)

Boiling Point: 545.7±60.0 °C at 760 mmHg

Application: Arabinofuranosyl-cytosine (ara-C) is an inhibitor of DNA synthesis.

InChIKey: UHDGCWIWMRVCDJ-CCXZUQQUSA-N

Solubility: Soluble in DMSO (Slightly, Heated), Ethanol (Slightly), Methanol (Slightly, Heated), Water

CanonicalSMILES: O=C1N=C(C=CN1[C@H]2[C@@H](O)[C@H](O)[C@@H](CO)O2)N

IUPAC Name: 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1

Synonyms: 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone; (Arabinofuranosyl)cytosine; 1-(Arabinofuranosyl)cytosine; 1-(β-D-Arabinofuranosyl)cytosine; 1-β-D-Arabinosylcytosine; 1-β-Arabinofuranosylcytosine; 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine; Ac 1075; Alexan; Ara-C; Ara-cell; ara-Cytosine; Arabinocytosine; Arabinoside C; Arabitin; Aracytidine; Aracytin; Aracytine; Arafcyt; Citozar; Cyclocide; Cylocide; Cylocide N; Cytarabin; Cytarabinoside; Cytosar; Cytosar U; Cytosine arabinoside; Cytosine β-D-arabinofuranoside; Cytosine β-D-arabinoside; Cytosine-1-β-D-arabinofuranoside; Cytosine-1-β-arabinofuranoside; DepoCyt; DepoCyte; Erpalfa; Iretin; MK 8242; NSC 287459; NSC 63878; SCH 900242; Spongocytidine; Tarabine PFS; U 19920; U 19920A; Udicil

Related CAS: 69-74-9 ; (hydrochloride)

Cytidine

Description: Cytidine is a nucleoside molecule that is formed when cytosine is attached to a ribose ring, cytidine is a component of RNA.

CAT: BRP-00200

CAS: 65-46-3

Molecular Formula: C9H13N3O5

Molecular Weight: 243.22

Purity: ≥98% by HPLC

Appearance: White crystalline powder

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Storage: Store at 2-8 °C

Density: 1.89±0.1 g/cm3

Melting Point: 230.5 °C (dec.)

Boiling Point: 545.7±60.0 °C at 760 mmHg

Flash Point: 283.8°C

InChIKey: UHDGCWIWMRVCDJ-XVFCMESISA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O

IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1

Synonyms: Cytarabine Impurity E; 4-Amino-1-β-D-ribofuranosylpyrimidin-2(1H)-one; Cytosine riboside; MK-0431; MK 0431; MK0431; ribo Cytidine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-(amino)pyrimidin-2(1H)-one; 1-(β-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine; 1-β-D-Ribofuranosylcytosine; 4-Amino-1-β-D-ribofuranosyl-2(1H)-pyrimidinone; NSC 20258; β-D-Cytidine; Cytarabine EP Impurity E

2-Iodoadenosine

Description: An intermediate in the synthesis of isoguanosine (crotonoside or 2-hydroxyadenosine), a naturally occuring nucleoside analogue of guanosine. Isoguanosine is incorporated into mammalian but not bacterial nucleic acids, stimulates the accumulation of cyclic AMP in the brain, and is an inhibitor of IMP (pyrophosphorylase).

CAT: BRP-00201

CAS: 35109-88-7

Molecular Formula: C10H12IN5O4

Molecular Weight: 393.14

Purity: ≥95%

Appearance: Off-White to Pale Yellow Solid

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Storage: Store at 2-8°C under inert atmosphere

Density: 2.69±0.1 g/cm3 (Predicted)

Melting Point: >190°C (dec.)

Boiling Point: 776.3±70.0°C (Predicted)

InChIKey: MGEBVSZZNFOIRB-UUOKFMHZSA-N

Solubility: Soluble in DMSO, Hot Methanol, Water

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(N=C2N)I

IUPAC Name: (2R,3R,4S,5R)-2-(6-amino-2-iodopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H12IN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1

Synonyms: 2-Iodo Adenosine; 6-Amino-2-iodo-9-(beta-D-ribofuranosyl)purine; (2R,3R,4S,5R)-2-(6-amino-2-iodo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

5'-Tosyl Adenosine

Description: 5'-Tosyl Adenosine is a chemically modified adenosine nucleotide in which the 5'-hydroxyl group of adenosine is substituted with a tosyl (p-toluenesulfonyl) group. This modification makes it a useful intermediate in organic synthesis and nucleoside chemistry. The tosyl group acts as a leaving group, facilitating various chemical reactions, such as nucleophilic substitutions, that can introduce other functional groups at the 5' position of adenosine. 5'-Tosyl Adenosine is often utilized in the preparation of modified nucleotides for research in biochemistry and molecular biology.

CAT: BRP-00202

CAS: 5135-30-8

Molecular Formula: C17H19N5O6S

Molecular Weight: 421.43

Purity: ≥95%

Appearance: White to off-white solid

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Storage: Store at 2-8 °C (under dark)

Density: 1.8±0.1 g/cm³

Melting Point: 151 °C

Boiling Point: 760.1±70.0 °C at 760 mmHg

InChIKey: CAXLRAROZXYOHH-LSCFUAHRSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Heated)

CanonicalSMILES: CC1=CC=C(C=C1)S(=O)(=O)OCC2C(C(C(O2)N3C=NC4=C3N=CN=C4N)O)O

IUPAC Name: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl 4-methylbenzenesulfonate

InChI: InChI=1S/C17H19N5O6S/c1-9-2-4-10(5-3-9)29(25,26)27-6-11-13(23)14(24)17(28-11)22-8-21-12-15(18)19-7-20-16(12)22/h2-5,7-8,11,13-14,17,23-24H,6H2,1H3,(H2,18,19,20)/t11-,13-,14-,17-/m1/s1

Synonyms: Adenosine 5'-(4-Methylbenzenesulfonate); 5'-O-Toluenesulfonyladenosine; 5'-Tosyladenosine

2-Chloroadenosine

Description: 2-Chloroadenosine is a nucleoside antibiotic produced by Streptomyces rishiensis. It has anti-gram-positive and negative bacteria activity.

CAT: BRP-00203

CAS: 146-77-0

Molecular Formula: C10H12ClN5O4

Molecular Weight: 301.69

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at -20°C

Density: 2.19 g/cm3

Melting Point: 133-136 °C (dec.)

Boiling Point: 591.8°C at 760 mmHg

InChIKey: BIXYYZIIJIXVFW-UUOKFMHZSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)

CanonicalSMILES: C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)Cl)N

IUPAC Name: (2R,3R,4S,5R)-2-(6-amino-2-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H12ClN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1

Synonyms: AT-265-B; AT-265B; 6-Amino-2-chloropurine riboside; (2R,3R,4S,5R)-2-(6-amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2-Chloro-9-(beta-D-ribofuranosyl)adenine; 2-Chlor-9-(β-D-ribofuranosyl)-9H-purin-6-amine; 2'-Chloroadenosine

Related CAS: 81012-94-4 (hemihydrate)

2-Aminoadenosine

Description: It is a nucleoside analogue as an inhibitor or substrate of adenosine kinase from M. tuberculosis.

CAT: BRP-00204

CAS: 2096-10-8

Molecular Formula: C10H14N6O4

Molecular Weight: 282.26

Purity: ≥95%

Appearance: White to off-white solid

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Storage: Store at 2-8 °C

Density: 2.25±0.1 g/cm³ (Predicted)

Melting Point: 241-243 °C (dec.)

Boiling Point: 798.5±70.0 °C at 760 mmHg

InChIKey: ZDTFMPXQUSBYRL-UUOKFMHZSA-N

Solubility: Soluble in Aqueous Acid (Slightly, Heated, Sonicated), DMSO (Slightly, Sonicated), Ethanol

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(N=C2N)N

IUPAC Name: (2R,3R,4S,5R)-2-(2,6-diaminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H14N6O4/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H4,11,12,14,15)/t3-,5-,6-,9-/m1/s1

Synonyms: 2,6-Diamino-9-β-D-ribofuranosyl-9H-purine; 2,6-Diaminonebularine; 9-β-Ribosyl-2,6-diaminopurine; 2,6-Diaminopurine Riboside; 2,6-Diaminopurinosine; NSC 7363; 9-β-D-Ribofuranosyl-9H-purine-2,6-diamine; 2,6-Diaminopurine Ribonucleoside; 2,6-Diamino-9-β-D-ribofuranosylpurine

Vidarabine

Description: 9-β-D-Arabinof uranosyladenine is a nucleoside antibiotic produced by Streptomyces antibioticusm and Str. herbaceusm. It has a strong weeding effect on a variety of monocotyledonous and dicotyledonous plants.

CAT: BRP-00205

CAS: 5536-17-4

Molecular Formula: C10H13N5O4

Molecular Weight: 267.24

Purity: ≥95%

Appearance: White to Off-white Crystalline Powder

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Storage: Store at -20°C under inert atmosphere

Density: 2.08 g/cm3

Melting Point: 260-265°C (dec.)

Boiling Point: 676.3°C at 760 mmHg

Flash Point: 362.8±34.3 °C

InChIKey: OIRDTQYFTABQOQ-UHTZMRCNSA-N

Solubility: Soluble in DMSO (Slightly, Heated), DMF (10 mg/mL), Ethanol (<1 mg/mL at 25°C), Water

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N

IUPAC Name: (2R,3S,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7+,10-/m1/s1

Synonyms: Ara-adenosine; 9-β-D-Arabinofuranosyladenine; 9-(b-D-Arabinofuranosyl)adenine; Adenine arabinoside; Arabinosyladenine; Spongoadenosine; Araadenosine; Arabinosyl adenine; (2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 9-β-D-Arabinofuranosyl-9H-purin-6-amine; Adenine Arabinofuranoside

Related CAS: 24356-66-9 (monohydrate)

2'-O-(2-Methoxyethy)uridine

Description: It is a derivative of uridine that acts as a building block for crosslinking oligonucleotides.

CAT: BRP-00312

CAS: 223777-15-9

Molecular Formula: C12H18N2O7

Molecular Weight: 302.28

Purity: ≥95%

Appearance: White to Orange Powder

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Storage: Store at -20°C

Density: 1.46±0.1 g/cm3 (Predicted)

InChIKey: XTXNROBDOKPICP-QCNRFFRDSA-N

CanonicalSMILES: COCCOC1C(C(OC1N2C=CC(=O)NC2=O)CO)O

IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C12H18N2O7/c1-19-4-5-20-10-9(17)7(6-15)21-11(10)14-3-2-8(16)13-12(14)18/h2-3,7,9-11,15,17H,4-6H2,1H3,(H,13,16,18)/t7-,9-,10-,11-/m1/s1

Synonyms: Uridine, 2'-O-(2-methoxyethyl)-; 2'-O-Methoxyethyluridine; 1-[(2R,3S,4S,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl]pyrimidine-2,4-dione; 2'-O-MOE Uridine; 2'-O-MOE-rU

2'-O-methylinosine

Description: It is a novel nucleoside that is a component of rRNA of Crithidia fasciculata. In addition, it has intrinsic hypotensive activity and is also an apoptosis-inducing nucleoside (AINs).

CAT: BRP-00313

CAS: 3881-21-8

Molecular Formula: C11H14N4O5

Molecular Weight: 282.25

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: Store at RT

Density: 1.84±0.1 g/cm3 (Predicted)

Melting Point: 153-156°C

Boiling Point: 724.3±60.0°C (Predicted)

Symbol: Im

InChIKey: HPHXOIULGYVAKW-IOSLPCCCSA-N

Solubility: Soluble in Water (Slightly)

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=CNC3=O)CO)O

IUPAC Name: 9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C11H14N4O5/c1-19-8-7(17)5(2-16)20-11(8)15-4-14-6-9(15)12-3-13-10(6)18/h3-5,7-8,11,16-17H,2H2,1H3,(H,12,13,18)/t5-,7-,8-,11-/m1/s1

Synonyms: Inosine, 2'-O-methyl-; 2'-O-Methyl-inosine; 2'-(o-Methyl)-inosine; 9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-ol; 2'-(O-Methyl) Inosine

2'-O-(2-Methoxyethyl)cytidine

Description: It is a cytidine derivative as a building block for crosslinking oligonucleotides.

CAT: BRP-00314

CAS: 223777-16-0

Molecular Formula: C12H19N3O6

Molecular Weight: 301.30

Purity: ≥95%

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Storage: Store at -20°C

Density: 1.57±0.1 g/cm3 (Predicted)

Boiling Point: 535.3±60.0°C (Predicted)

InChIKey: YKOGMMXZKKVMBT-QCNRFFRDSA-N

CanonicalSMILES: COCCOC1C(C(OC1N2C=CC(=NC2=O)N)CO)O

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C12H19N3O6/c1-19-4-5-20-10-9(17)7(6-16)21-11(10)15-3-2-8(13)14-12(15)18/h2-3,7,9-11,16-17H,4-6H2,1H3,(H2,13,14,18)/t7-,9-,10-,11-/m1/s1

Synonyms: Cytidine, 2'-O-(2-methoxyethyl)-; 4-amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2'-O-methoxyethylcytidine; 2'-O-MOE Cytidine; 2'-O-MOE-rC

N2-Isobutyryl-2',3'-diacetylguanosine

Description: N2-Isobutyryl-2',3'-diacetylguanosine is an essential biomedical compound, exhibiting unparalleled potential in arresting cancer cell proliferation and thwarting viral replication.

CAT: BRP-00316

CAS: 163586-86-5

Molecular Formula: C18H23N5O8

Molecular Weight: 437.40

Purity: ≥95%

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Storage: Store at -20 °C

Density: 1.62±0.1 g/cm3

InChIKey: HWVKXBNLKJAPSV-CNEMSGBDSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)OC(=O)C)OC(=O)C

IUPAC Name: [(2R,3R,4R,5R)-4-acetyloxy-2-(hydroxymethyl)-5-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl] acetate

InChI: InChI=1S/C18H23N5O8/c1-7(2)15(27)21-18-20-14-11(16(28)22-18)19-6-23(14)17-13(30-9(4)26)12(29-8(3)25)10(5-24)31-17/h6-7,10,12-13,17,24H,5H2,1-4H3,(H2,20,21,22,27,28)/t10-,12-,13-,17-/m1/s1

Synonyms: N2-iBu-2',3'-Acetyl-Guanosine; N-Isobutyryl-2',3'-Acetyl-Guanosine; Guanosine-9-17N, N-(2-methyl-1-oxopropyl)-, 2',3'-diacetate; N-(2-Methyl-1-oxopropyl)guanosine, 2',3'-diacetate; 2',3'-Diacetyl Guanosine (n-ibu)

2'-O-(2-Methoxyethyl)inosine

Description: 2'-O-(2-Methoxyethyl)inosine is a potent nucleoside analog widely used in biomedical research and drug development. It exhibiting antiviral activity against RNA viruses such as influenza and hepatitis C. Additionally, it has shown promising potential in the reserch of various cancers, including colorectal and liver cancer.

CAT: BRP-00349

CAS: 545374-76-3

Molecular Formula: C13H18N4O6

Molecular Weight: 326.31

Purity: ≥95%

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Storage: Store at 2-8 °C

InChIKey: YVCRYUJBJVEBAK-QYVSTXNMSA-N

CanonicalSMILES: COCCOC1C(C(OC1N2C=NC3=C2N=CNC3=O)CO)O

IUPAC Name: 9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one

InChI: InChI=1S/C13H18N4O6/c1-21-2-3-22-10-9(19)7(4-18)23-13(10)17-6-16-8-11(17)14-5-15-12(8)20/h5-7,9-10,13,18-19H,2-4H2,1H3,(H,14,15,20)/t7-,9-,10-,13-/m1/s1

Synonyms: 2'-O-MOE-rI; 2'-o-methoxyethyl inosine; Inosine, 2'-O-(2-methoxyethyl)-; 9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-1H-purin-6-one

5-Methylcytidine

Description: 5-Methylcytidine is a derivative of Cytidine, found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. 5-Methylcytidine is one of many nucleosides that can be used as biomedical marker using liquid chromatography and ion trap mass spectrometry coupling.

CAT: BRP-00350

CAS: 2140-61-6

Molecular Formula: C10H15N3O5

Molecular Weight: 257.24

Purity: ≥98% by HPLC

Appearance: Off-white to pale beige solid

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Storage: Store at 2-8 °C, under inert atmosphere

Density: 1.79±0.1 g/cm³

Melting Point: 212-215 °C (dec.)

Boiling Point: 537.5±60.0 °C at 760 mmHg

Symbol: m⁵C

InChIKey: ZAYHVCMSTBRABG-JXOAFFINSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Sparingly)

CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O

IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one

InChI: InChI=1S/C10H15N3O5/c1-4-2-13(10(17)12-8(4)11)9-7(16)6(15)5(3-14)18-9/h2,5-7,9,14-16H,3H2,1H3,(H2,11,12,17)/t5-,6-,7-,9-/m1/s1

Synonyms: Cytarabine Impurity G; 4-Amino-5-methyl-1-β-D-ribofuranosylpyrimidin-2(1H)-one; 5-Me-rC; 5-Methyl-cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one; NSC 363933; 5-Methyl-D-cytidine; 5-Methyl-ribo Cytidine; Cytarabine EP Impurity G

N4-Benzoyl-2'-O-(2-methoxyethyl)-5-methylcytidine

Description: N4-Benzoyl-2'-O-(2-methoxyethyl)-5-methylcytidine, an extraordinary compound utilized in the biomedical sector, showcases robust antiviral properties. Its efficacy is notably significant against RNA viruses such as respiratory syncytial virus (RSV) and coronaviruses. By selectively inhibiting viral replication through the precise targeting of viral RNA polymerases, it presents itself as a compelling contender for the advancement of groundbreaking antiviral therapeutics. With its multifaceted mechanisms of action, this compound holds immense promise in the realm of cutting-edge antiviral research and development.

CAT: BRP-00351

CAS: 340162-93-8

Molecular Formula: C20H25N3O7

Molecular Weight: 419.43

Purity: ≥95%

Appearance: White, off-white to faint yellow powder

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Storage: Store at 2-8 °C, Keep in a dark and dry place

Density: 1.41±0.1 g/cm3

InChIKey: LGGHYGUGIGYDFX-YKTARERQSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)CO)O)OCCOC

IUPAC Name: N-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C20H25N3O7/c1-12-10-23(19-16(29-9-8-28-2)15(25)14(11-24)30-19)20(27)22-17(12)21-18(26)13-6-4-3-5-7-13/h3-7,10,14-16,19,24-25H,8-9,11H2,1-2H3,(H,21,22,26,27)/t14-,15-,16-,19-/m1/s1

Synonyms: N-Benzoyl-2'-O-(2-methoxyethyl)-5-methylcytidine; N-(1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide; Cytidine, N-benzoyl-2'-O-(2-methoxyethyl)-5-methyl-; 2'-O-MOE-5-Me-rC(Bz); N4-Bz-5-Me-2'-O-MOE-C; N4-benzoyl-5-methyl-2'-O-methoxyethylcytidine

N6-Benzoyl-2'-O,4'-C-methyleneadenosine

Description: N6-Benzoyl-2'-O,4'-C-methyleneadenosine, a highly efficacious agent employed in the realm of biomedicine due to its remarkable anticancer attributes, stands out in the selective eradication of malignant cells via the potent suppression of neoplastic cell proliferation and the initiation of programmed cell death. Notably, this product holds immense potential for the advancement of avant-garde therapeutic strategies devoted to diverse cancer types, encompassing breast, lung, and prostate cancer. Its exceptional mode of action lies in the targeted inhibition of specific enzymes and pathways vital in the malignant cascade, rendering it an exceedingly auspicious contender for antineoplastic interventions.

CAT: BRP-00352

CAS: 209968-94-5

Molecular Formula: C18H17N5O5

Molecular Weight: 383.36

Purity: ≥95%

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Storage: Store at 2-8 °C

Density: 1.7±0.1 g/cm3

InChIKey: LWLHBOKWFIOXPA-OBQMCUGOSA-N

CanonicalSMILES: C1C2(C(C(O1)C(O2)N3C=NC4=C(N=CN=C43)NC(=O)C5=CC=CC=C5)O)CO

IUPAC Name: N-[9-[(1S,3R,4R,7S)-7-hydroxy-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl]purin-6-yl]benzamide

InChI: InChI=1S/C18H17N5O5/c24-6-18-7-27-12(13(18)25)17(28-18)23-9-21-11-14(19-8-20-15(11)23)22-16(26)10-4-2-1-3-5-10/h1-5,8-9,12-13,17,24-25H,6-7H2,(H,19,20,22,26)/t12-,13+,17-,18+/m1/s1

Synonyms: 9-[2,5-Anhydro-4-(hydroxymethyl)-α-L-lyxofuranosyl]-N-benzoyl-9H-purin-6-amine; (1S,3R,4R,7S)-7-Hydroxy-1-hydroxymethyl-3-(6-N-benzoyladenin-9-yl)-2,5-dioxabicyclo-[2.2.1]heptane; LNA-A(Bz); (1S,3R,4R,7S)-3-(6-N-benzoyladenine-9-yl)-7-hydroxy-1-hydroxymethyl-2,5-dioxabicyclo[2.2.1]heptane; 2'-O-4'-C-Locked-rA(Bz)

2'-Deoxy-L-uridine

Description: 2'-Deoxy-L-uridine is a valuable nucleoside analogue commonly used in the biomedical industry playing a crucial role in the research and development of RNA and DNA.

CAT: BRP-00353

CAS: 31501-19-6

Molecular Formula: C9H12N2O5

Molecular Weight: 228.20

Purity: ≥95% by HPLC

Appearance: White to off-white powder

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Storage: Store at 2-8 °C

Density: 1.533±0.06 g/cm3(Predicted)

InChIKey: MXHRCPNRJAMMIM-CHKWXVPMSA-N

CanonicalSMILES: C1C(C(OC1N2C=CC(=O)NC2=O)CO)O

IUPAC Name: 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m1/s1

Synonyms: 1-((2S,4R,5S)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; L-2'-dU; 1-(2-Deoxy-β-L-erythro-pentofuranosyl)-2,4(1H,3H)-pyrimidinedione; Uracil, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-; 2'-Deoxy-β-L-uridine

Related CAS: 189282-17-5 (1-(2-Deoxy-α-L-erythro-pentofuranosyl)-2,4(1H,3H)-pyrimidinedione)

2'-O-Propargyluridine

Description: This cutting-edge product, 2'-O-Propargyluridine, plays a pivotal role in the realm of biomedicine. It serves as a crucial component in the treatment and comprehension of diverse diseases. Specifically, this modified nucleoside exhibits the exceptional ability to integrate into RNA molecules, thereby facilitating the exploration of RNA's intricate structure and functionality. Furthermore, this remarkable compound finds application in the development of antiviral medications, functioning as an invaluable research instrument for unraveling the complexities of RNA biology and viral replication mechanisms.

CAT: BRP-00354

CAS: 129778-58-1

Molecular Formula: C12H14N2O6

Molecular Weight: 282.25

Purity: 97%

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Storage: Store at 2-8 °C

InChIKey: SJIYVXTZWZSVLZ-QCNRFFRDSA-N

CanonicalSMILES: C#CCOC1C(C(OC1N2C=CC(=O)NC2=O)CO)O

IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-prop-2-ynoxyoxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C12H14N2O6/c1-2-5-19-10-9(17)7(6-15)20-11(10)14-4-3-8(16)13-12(14)18/h1,3-4,7,9-11,15,17H,5-6H2,(H,13,16,18)/t7-,9-,10-,11-/m1/s1

Synonyms: 2'-O-2-Propyn-1-yluridine; 2'-O-Propargyl-D-uridine; 2'-O-propargyl-rU; 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-O-propargyl-uridine; 2'-O-propargyl-Ur; 2'-(O-propargyl) Uridine

N4-Benzoyl-2'-O-propargyladenosine

Description: N4-Benzoyl-2'-O-propargyladenosine is a versatile biomedical compound, used for studying diverse viral infections, encompassing notorious culprits like HIV and herpes viruses. Its unrivaled potence resides in the ability to hamper viral replication.

CAT: BRP-00355

CAS: 210096-44-9

Molecular Formula: C20H19N5O5

Molecular Weight: 409.40

Purity: ≥95%

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Storage: Store at 2-8 °C

Density: 1.49±0.1 g/cm3

InChIKey: ADMKUOVXGJZAMV-KHTYJDQRSA-N

CanonicalSMILES: C#CCOC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O

IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-prop-2-ynoxyoxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C20H19N5O5/c1-2-8-29-16-15(27)13(9-26)30-20(16)25-11-23-14-17(21-10-22-18(14)25)24-19(28)12-6-4-3-5-7-12/h1,3-7,10-11,13,15-16,20,26-27H,8-9H2,(H,21,22,24,28)/t13-,15-,16-,20-/m1/s1

Synonyms: N6-Benzoyl-2'-O-(2-propyn-1-yl)adenosine; N4-Benzoyl-2'-O-(2-propyn-1-yl)adenosine; N-(9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide; 2'-O-(1-propyn-3-yl)-6-N-benzoyladenosine; Adenosine, N-benzoyl-2'-O-2-propyn-1-yl-; 2'-O-propargyl-rA(Bz); N-Benzoyl-2'-O-2-propyn-1-yladenosine; N-Benzoyl-2'-O-propargyladenosine; N6-Bz-2'-O-propargyl-Ar; N6-Bz-2'-O-propargyl-adenosine

N2-iso-Butyroyl-2'-O-propargylguanosine

Description: N2-iso-Butyroyl-2'-O-propargylguanosine, an indispensable pharmaceutical compound employed in the biomedical sector, manifests substantial prospects for antiviral drug advancement. It displays commendable efficacy against RNA virus-induced infections, rendering it valuable in combating diseases encompassing hepatitis C and respiratory syncytial viruses.

CAT: BRP-00356

CAS: 2095417-55-1

Molecular Formula: C17H21N5O6

Molecular Weight: 391.38

Purity: ≥95%

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Storage: Store at 2-8 °C

Density: 1.56±0.1 g/cm3

InChIKey: NAZLVNVVZNYAAV-UBEDBUPSSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)OCC#C

IUPAC Name: N-[9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-prop-2-ynoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C17H21N5O6/c1-4-5-27-12-11(24)9(6-23)28-16(12)22-7-18-10-13(22)19-17(21-15(10)26)20-14(25)8(2)3/h1,7-9,11-12,16,23-24H,5-6H2,2-3H3,(H2,19,20,21,25,26)/t9-,11-,12-,16-/m1/s1

Synonyms: 2'-O-propargyl-rG(iBu); N-(9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; N2-iBu-2'-O-propargyl-Gr; N2-iBu-2'-O-propargyl-guanosine