What are nucleosides used for?

Nucleosides are base molecules used as starting materials for synthesizing nucleotides and phosphoramidites.

What is the difference between nucleosides and nucleotides?

Nucleosides lack phosphate groups, while nucleotides contain one or more phosphates required for enzymatic reactions.

Are nucleosides used directly in enzymatic reactions?

Nucleosides are typically chemically modified before being used in enzymatic workflows.

Can nucleosides be chemically modified?

Yes, modified nucleosides are widely used to introduce structural or functional changes in nucleic acids.

Why is nucleoside purity important?

High purity ensures correct downstream synthesis of nucleotides and phosphoramidites with predictable performance.

Nucleosides - RNA / BOC Sciences

3',5'-TIPS-N-Ac-Adenosine

Description: 3',5'-TIPS-N-Ac-Adenosine, a crucial nucleoside employed in biomedicine, exhibits remarkable anti-inflammatory prowess. Its immunosuppressive effects enable the management of allergic ailments such as asthma and allergic rhinitis.

CAT: BRP-00176

CAS: 828247-65-0

Molecular Formula: C24H41N5O6Si2

Molecular Weight: 551.78

Purity: ≥95%

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Density: 1.29±0.1 g/cm3 (Predicted)

InChIKey: ZULOPXIJTCCZDJ-UMCMBGNQSA-N

CanonicalSMILES: CC(C)[Si]1(OCC2C(C(C(O2)N3C=NC4=C(N=CN=C43)NC(=O)C)O)O[Si](O1)(C(C)C)C(C)C)C(C)C

IUPAC Name: N-[9-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]purin-6-yl]acetamide

InChI: InChI=1S/C24H41N5O6Si2/c1-13(2)36(14(3)4)32-10-18-21(34-37(35-36,15(5)6)16(7)8)20(31)24(33-18)29-12-27-19-22(28-17(9)30)25-11-26-23(19)29/h11-16,18,20-21,24,31H,10H2,1-9H3,(H,25,26,28,30)/t18-,20-,21-,24-/m1/s1

Synonyms: N-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine; 3',5'-TIPS-N-Acetyl-adenosine; N-Acetyl-3'-O,5'-O-[oxybis(diisopropylsilanediyl)]adenosine; N6-Acetyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-adenosine; N-{9-[(6aR,8R,9R,9aS)-9-Hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-9H-purin-6-yl}acetamide

3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine

Description: 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine, a bioactive agent synthesized for biomedical applications, demonstrates exceptional efficacy in combating specific viral infections namely, hepatitis C and respiratory syncytial virus (RSV). By exerting potent antiviral effects, this compound significantly impedes viral replication, culminating in the effective prevention and management of these viral infections.

CAT: BRP-00177

CAS: 69304-38-7

Molecular Formula: C21H38N2O7Si2

Molecular Weight: 486.71

Purity: ≥98% by HPLC

Appearance: White to off-white crystalline powder

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Storage: Store at RT

Density: 1.17±0.1 g/cm3

Melting Point: 75-76 °C

InChIKey: KKLQDUCRZCCKHG-VBSBHUPXSA-N

CanonicalSMILES: CC(C)[Si]1(OCC2C(C(C(O2)N3C=CC(=O)NC3=O)O)O[Si](O1)(C(C)C)C(C)C)C(C)C

IUPAC Name: 1-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C21H38N2O7Si2/c1-12(2)31(13(3)4)27-11-16-19(29-32(30-31,14(5)6)15(7)8)18(25)20(28-16)23-10-9-17(24)22-21(23)26/h9-10,12-16,18-20,25H,11H2,1-8H3,(H,22,24,26)/t16-,18-,19-,20-/m1/s1

Synonyms: 3',5'-TIPS-Uridine; 3',5'-TIPPS-uridine; 3',5'-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl]uridine; 3',5'-O-(1,1,3,3-Tetraisopropyldisiloxan-1,3-diyl)uridine; 3',5'-O-(Tetraisopropyldisiloxanediyl)uridine; 3',5'-TIPDS-Ur

N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine

Description: N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)guanosine is a compound, exhibiting great application for studying distinctive maladies. Its usage encompasses the development of pharmaceutical drugs that precisely modulate guanosine metabolism.

CAT: BRP-00178

CAS: 87865-78-9

Molecular Formula: C26H45N5O7Si2

Molecular Weight: 595.84

Purity: ≥95%

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InChIKey: RYRMXMSXLHPLAT-GUQHISFFSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C4C(O3)CO[Si](O[Si](O4)(C(C)C)C(C)C)(C(C)C)C(C)C)O

IUPAC Name: N-[9-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C26H45N5O7Si2/c1-13(2)23(33)29-26-28-22-19(24(34)30-26)27-12-31(22)25-20(32)21-18(36-25)11-35-39(14(3)4,15(5)6)38-40(37-21,16(7)8)17(9)10/h12-18,20-21,25,32H,11H2,1-10H3,(H2,28,29,30,33,34)/t18-,20-,21-,25-/m1/s1

Synonyms: N2-Isobutyryl-3',5'-O-TIPPS-guanosine; 3',5'-O-TIPPS-N2-isobutyrylguanosine; N2-Isobutyryl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-D-guanosine; 9-[3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranosyl]-N2-isobutyrylguanine; N2-isobutyryl-9-[3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranosyl]guanine; 3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-N2-isobutyroylguanosine; 2'-O-(1,1-dioxo-1λ6-thiomorpholine-4-carbothioate)-N2-isobutyrylguanosine; N2-iBu-3',5'-TIPDS-Gr; N2-iBu-3',5'-O-TIPDS-guanosine

N4-Benzoyl-3 ,5 -O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine

Description: N4-Benzoyl-3,5-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine, a formidable biomedical agent, stands as a beacon of hope in the realm of viral infection treatment. Acutely attuned to cytidine-sensitive viruses, this compound, hailing from the prestigious nucleoside analog drug family, adroitly disrupts the replication mechanism ensnaring the targeted foes.

CAT: BRP-00179

CAS: 69304-43-4

Molecular Formula: C28H43N3O7Si2

Molecular Weight: 589.83

Purity: ≥98%

Appearance: White or almost white crystalline powder

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Storage: Store at RT

Density: 1.23±0.1 g/cm3(Predicted)

Melting Point: 101 °C

InChIKey: NFIAUHQTSCWVMS-LYPBTDJXSA-N

CanonicalSMILES: CC(C)[Si]1(OCC2C(C(C(O2)N3C=CC(=NC3=O)NC(=O)C4=CC=CC=C4)O)O[Si](O1)(C(C)C)C(C)C)C(C)C

IUPAC Name: N-[1-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C28H43N3O7Si2/c1-17(2)39(18(3)4)35-16-22-25(37-40(38-39,19(5)6)20(7)8)24(32)27(36-22)31-15-14-23(30-28(31)34)29-26(33)21-12-10-9-11-13-21/h9-15,17-20,22,24-25,27,32H,16H2,1-8H3,(H,29,30,33,34)/t22-,24-,25-,27-/m1/s1

Synonyms: N-Benzoyl-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-Cytidine; 3',5'-TIPS-N-Bz-Cytidine; N4-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)cytidine; 3',5'-TIPS-N4-Benzoyl-cytidine

N6-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine

CAT: BRP-00180

CAS: 79154-57-7

Molecular Formula: C29H43N5O6Si2

Molecular Weight: 613.87

Purity: ≥98%

Appearance: White or almost white crystalline powder

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Storage: Store at RT

InChIKey: MYWCSMGAHXNSPA-UQCYUJMQSA-N

CanonicalSMILES: CC(C)[Si]1(OCC2C(C(C(O2)N3C=NC4=C(N=CN=C43)NC(=O)C5=CC=CC=C5)O)O[Si](O1)(C(C)C)C(C)C)C(C)C

IUPAC Name: N-[9-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]purin-6-yl]benzamide

InChI: InChI=1S/C29H43N5O6Si2/c1-17(2)41(18(3)4)37-14-22-25(39-42(40-41,19(5)6)20(7)8)24(35)29(38-22)34-16-32-23-26(30-15-31-27(23)34)33-28(36)21-12-10-9-11-13-21/h9-13,15-20,22,24-25,29,35H,14H2,1-8H3,(H,30,31,33,36)/t22-,24-,25-,29-/m1/s1

Synonyms: 3',5'-TIPS-N-Bz-Adenosine; N6-Benzoyl-3',5'-O-TIPPS-adenosine; 3',5'-O-TIPPS-N6-benzoyladenosine; N6-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-D-adenosine

2',3',6'-TAc-Ino

Description: 2',3',6'-TAc-Ino, also known as Inosine Triacetate, is a nucleoside analogue utilized in the study of RNA structure and function. It's also used in antiviral drug development targeting diseases like hepatitis C and the flu.

CAT: BRP-00181

CAS: 3181-38-2

Molecular Formula: C16H18N4O8

Molecular Weight: 394.34

Purity: ≥97% by HPLC

Appearance: Crystal Powder

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Storage: Store at 2-8°C

Density: 1.62±0.1 g/cm3

Melting Point: 234-236°C

Boiling Point: 620.7±65.0 °C at 760 mmHg

InChIKey: SFEQTFDQPJQUJM-XNIJJKJLSA-N

Solubility: Soluble in Methanol (Sparingly), Water (Sparingly)

CanonicalSMILES: CC(=O)OCC1C(C(C(O1)N2C=NC3=C2N=CNC3=O)OC(=O)C)OC(=O)C

IUPAC Name: [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl acetate

InChI: InChI=1S/C16H18N4O8/c1-7(21)25-4-10-12(26-8(2)22)13(27-9(3)23)16(28-10)20-6-19-11-14(20)17-5-18-15(11)24/h5-6,10,12-13,16H,4H2,1-3H3,(H,17,18,24)/t10-,12-,13-,16-/m1/s1

Synonyms: 2',3',5'-Tri-O-Acetyl-Inosine; NSC 66386; (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate; O2',O3',O5'-tri-acetylinosine; Inosine 2',3',5'-triacetate

2',3',5'-Tri-O-acetyl-cytidine hydrochloride

Description: 2',3',5'-Tri-O-acetyl-cytidine hydrochloride, a chemical compound extensively used in biomedical research, is a modification of cytidine acetylated at its 2', 3', and 5' positions. This enhancement elevates the compound's stability and solubility that leads to easier experimental usage. Studies have investigated the efficacy of 2',3',5'-Tri-O-acetyl-cytidine hydrochloride as an effective antiviral therapy for viral infections like HIV and an antitumor drug.

CAT: BRP-00182

CAS: 63639-21-4

Molecular Formula: C15H19N3O8.HCl

Molecular Weight: 405.79

Purity: ≥97% by HPLC

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Melting Point: 34-38 °C

InChIKey: DMDAYVSFFBNVOE-VNQMUNOFSA-N

CanonicalSMILES: CC(=O)OCC1C(C(C(O1)N2C=CC(=NC2=O)N)OC(=O)C)OC(=O)C.Cl

IUPAC Name: [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl acetate;hydrochloride

InChI: InChI=1S/C15H19N3O8.ClH/c1-7(19)23-6-10-12(24-8(2)20)13(25-9(3)21)14(26-10)18-5-4-11(16)17-15(18)22;/h4-5,10,12-14H,6H2,1-3H3,(H2,16,17,22);1H/t10-,12-,13-,14-;/m1./s1

Synonyms: 2',3',5'-Tri-O-acetylcytidine HCl; (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate hydrochloride

Related CAS: 56787-28-1 (free base)

2',3',5'-Tri-O-acetyladenosine

Description: 2',3',5'-Tri-O-acetyladenosine is a chemical compound used in biomedicine as a precursor for synthesizing adenosine-containing drugs for the treatment of cardiovascular and neurological diseases, as well as cancer. It is also used as a tool compound for studying adenosine-based signaling pathways in cells.

CAT: BRP-00183

CAS: 7387-57-7

Molecular Formula: C16H19N5O7

Molecular Weight: 393.35

Purity: ≥95%

Appearance: White Solid

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Storage: Store at -20°C

Density: 1.62±0.1 g/cm3 (Predicted)

Melting Point: 168-170°C

Boiling Point: 594.1±60.0°C (Predicted)

InChIKey: GCVZNVTXNUTBFB-XNIJJKJLSA-N

Solubility: Soluble in Chloroform (Sparingly), DMSO (Slightly), Methanol (Sparingly)

CanonicalSMILES: CC(=O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)OC(=O)C)OC(=O)C

IUPAC Name: [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methyl acetate

InChI: InChI=1S/C16H19N5O7/c1-7(22)25-4-10-12(26-8(2)23)13(27-9(3)24)16(28-10)21-6-20-11-14(17)18-5-19-15(11)21/h5-6,10,12-13,16H,4H2,1-3H3,(H2,17,18,19)/t10-,12-,13-,16-/m1/s1

Synonyms: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-amino-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate; Adenosine 2',3',5'-Triacetate; Tri-O-acetyladenosine; NSC 76766; 2',3',5'-Tri-O-acetyl-D-adenosine; 2',3',5'-Tri-O-acetyl-β-D-ribofuranosyl adenine

PN401

Description: PN-401 is a synthetic uridine pro-drug that is converted to uridine in vivo. Uridine, a pyrimidine nucleotide, has been used in a variety of diseases including depressive disorders and inherited myopathies.

CAT: BRP-00184

CAS: 4105-38-8

Molecular Formula: C15H18N2O9

Molecular Weight: 370.314

Purity: 98%

Appearance: Off-white Powder

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Storage: Store at -20 °C, under inert atmosphere

Density: 1.43±0.1 g/cm3

Melting Point: 127-130 °C

InChIKey: AUFUWRKPQLGTGF-FMKGYKFTSA-N

Solubility: Soluble in Chloroform (Slightly), DCM, Dichloromethane (Slightly), DMF, DMSO (Slightly), Ethyl Acetate, Methanol

CanonicalSMILES: CC(=O)OCC1C(C(C(O1)N2C=CC(=O)NC2=O)OC(=O)C)OC(=O)C

IUPAC Name: [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl acetate

InChI: InChI=1S/C15H18N2O9/c1-7(18)23-6-10-12(24-8(2)19)13(25-9(3)20)14(26-10)17-5-4-11(21)16-15(17)22/h4-5,10,12-14H,6H2,1-3H3,(H,16,21,22)/t10-,12-,13-,14-/m1/s1

Synonyms: Uridine Triacetate; Triacetyluridine; 2',3',5'-Tri-O-Acetyluridine; Vistonuridine; 2',3',5'-Triacetyluridine; Uridine 2',3',5'-Triacetate; PN 401; RG 2133; Tri-O-acetyl uridine; PN-401; RG 2133; RG2133; RG-2133; Tri-O-acetyluridine

2',3',5'-Tri-O-acetyl Guanosine

Description: 2',3',5'-Tri-O-acetyl guanosine is a chemical compound commonly used in organic synthesis and nucleic acid chemistry. It features acetyl groups attached to the 2', 3', and 5' positions of the guanosine molecule. This modification serves to protect the reactive hydroxyl groups of guanosine, allowing for precise control over chemical reactions involving the nucleoside. It is often employed as a building block in the synthesis of modified nucleosides, nucleotides, and oligonucleotides for various research and biotechnological applications, including RNA interference, gene expression modulation, and pharmaceutical development.

CAT: BRP-00185

CAS: 6979-94-8

Molecular Formula: C16H19N5O8

Molecular Weight: 409.35

Purity: ≥98%

Appearance: White powder

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Storage: Store at 2-8 °C

Density: 1.7±0.1 g/cm³

Melting Point: 226-231 °C

Boiling Point: 655.8 °C at 760 mmHg

InChIKey: ULXDFYDZZFYGIY-SDBHATRESA-N

Solubility: Soluble in DMSO (Slightly)

CanonicalSMILES: CC(=O)OCC1C(C(C(O1)N2C=NC3=C2N=C(NC3=O)N)OC(=O)C)OC(=O)C

IUPAC Name: [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2-amino-6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl acetate

InChI: InChI=1S/C16H19N5O8/c1-6(22)26-4-9-11(27-7(2)23)12(28-8(3)24)15(29-9)21-5-18-10-13(21)19-16(17)20-14(10)25/h5,9,11-12,15H,4H2,1-3H3,(H3,17,19,20,25)/t9-,11-,12-,15-/m1/s1

Synonyms: 2',3',5'-Triacetylguanosine; Guanosine 2',3',5'-triacetate; Guanosine Triacetate; NSC 66387; Triacetylguanosine

2',3'-Ipr-Ino

Description: 2',3'-Ipr-Ino, an extraordinary biomedicine, exhibits profound efficacy in combating specific diseases. Renowned for its ability to combat RNA viruses, it has undergone comprehensive scrutiny and has consistently illustrated remarkable potential in suppressing the replication of diverse RNA viruses.

CAT: BRP-00186

CAS: 2140-11-6

Molecular Formula: C13H16N4O6

Molecular Weight: 308.29

Purity: 98%

Appearance: White Crystal Powder

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Storage: Store at 2-8°C

Density: 1.80±0.1 g/cm3

Melting Point: 263-272°C

Boiling Point: 606.6±65.0 °C at 760 mmHg

InChIKey: LIEKLUBCIPVWQD-WOUKDFQISA-N

CanonicalSMILES: CC1(OC2C(OC(C2O1)N3C=NC4=C3N=CNC4=O)CO)C

IUPAC Name: 9-[(3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-1H-purin-6-one

InChI: InChI=1S/C13H16N4O5/c1-13(2)21-8-6(3-18)20-12(9(8)22-13)17-5-16-7-10(17)14-4-15-11(7)19/h4-6,8-9,12,18H,3H2,1-2H3,(H,14,15,19)/t6-,8-,9-,12-/m1/s1

Synonyms: 2',3'-O-Isopropylideneinosine; 2',3'-Isopropylideneinosine; 2',3'-o-(1-methylethylidene)inosine

2',3'-O-Isopropylideneguanosine

Description: 2',3'-O-Isopropylideneguanosine is a modified nucleoside derivative of guanosine. It has an isopropylidene group attached at the 2' and 3' positions of the ribose ring. This modification can enhance the stability and bioavailability of the nucleoside, making it useful in pharmaceutical and biochemical research.

CAT: BRP-00187

CAS: 362-76-5

Molecular Formula: C13H17N5O5

Molecular Weight: 323.31

Purity: 98%

Appearance: White to Off-White Solid

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Storage: Store at 2-8°C (under dark)

Density: 1.93 g/cm3

Melting Point: 296 °C

Boiling Point: 647°C at 760 mmHg

InChIKey: XKPDAYWPKILAMO-IOSLPCCCSA-N

Solubility: Soluble in DMSO, Ethanol, Methanol

CanonicalSMILES: CC1(OC2C(OC(C2O1)N3C=NC4=C3N=C(NC4=O)N)CO)C

IUPAC Name: 9-[(3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-2-amino-1H-purin-6-one

InChI: InChI=1S/C13H17N5O5/c1-13(2)22-7-5(3-19)21-11(8(7)23-13)18-4-15-6-9(18)16-12(14)17-10(6)20/h4-5,7-8,11,19H,3H2,1-2H3,(H3,14,16,17,20)/t5-,7-,8-,11-/m1/s1

Synonyms: 2',3'-O-(1-Methylethylidene)guanosine; Guanosine, 2',3'-O-isopropylidene-; 2',3'-Isopropylideneguanosine; Isopropylideneguanosine; 2-Amino-9-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-1H-purin-6(9H)-one; 9-[(3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]-2-amino-3H-purin-6-one

2',3'-Di-O-isopropylidene adenosine

Description: It is used for special nucleoside.

CAT: BRP-00188

CAS: 362-75-4

Molecular Formula: C13H17N5O4

Molecular Weight: 307.31

Purity: ≥95%

Appearance: White to off-white solid

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Storage: Store at 2-8 °C

Density: 1.8±0.1 g/cm³

Melting Point: >214 °C (dec.)

Boiling Point: 570.5±60.0 °C at 760 mmHg

InChIKey: LCCLUOXEZAHUNS-UHFFFAOYSA-N

Solubility: Soluble in Dioxane (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: CC1(OC2C(OC(C2O1)N3C=NC4=C3N=CN=C4N)CO)C

IUPAC Name: [(3aR,4R,6R,6aR)-4-(6-aminopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methanol

InChI: InChI=1S/C13H17N5O4/c1-13(2)21-8-6(3-19)20-12(9(8)22-13)18-5-17-7-10(14)15-4-16-11(7)18/h4-6,8-9,12,19H,3H2,1-2H3,(H2,14,15,16)

Synonyms: 2',3'-O-(1-Methylethylidene)adenosine; NSC 29413; [(1R,2R,4R,5R)-4-(6-aminopurin-9-yl)-7,7-dimethyl-3,6,8-trioxabicyclo[3.3.0]oct-2-yl]methan-1-ol

Isoprinosine

Description: Isoprinosine is a complex of acetaminobenzoic acid, dimethylaminoisopropanol, and inosine with the ratio of 3:3:1. It is an immunomodulatory drug approved in several countries for the treatment of viral infections.

CAT: BRP-00189

CAS: 36703-88-5

Molecular Formula: C10H12N4O5.3C9H9NO3.3C5H13NO

Molecular Weight: 1115.23

Purity: ≥98% by HPLC

Appearance: White or almost white crystalline powder

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Storage: Store in a cool and dry place and at 2-8 °C for short term (days to weeks) or -20 °C for long term (months to years)

Flash Point: 397°C

InChIKey: YLDCUKJMEKGGFI-QCSRICIXSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: CC(CN(C)C)O.CC(CN(C)C)O.CC(CN(C)C)O.CC(=O)NC1=CC=C(C=C1)C(=O)O.CC(=O)NC1=CC=C(C=C1)C(=O)O.CC(=O)NC1=CC=C(C=C1)C(=O)O.C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: 4-acetamidobenzoic acid;9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one;1-(dimethylamino)propan-2-ol

InChI: InChI=1S/C10H12N4O5.3C9H9NO3.3C5H13NO/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18;3*1-6(11)10-8-4-2-7(3-5-8)9(12)13;3*1-5(7)4-6(2)3/h2-4,6-7,10,15-17H,1H2,(H,11,12,18);3*2-5H,1H3,(H,10,11)(H,12,13);3*5,7H,4H2,1-3H3/t4-,6-,7-,10-;;;;;;/m1....../s1

Synonyms: Inosine, compd. with 1-(dimethylamino)-2-propanol 4-(acetylamino)benzoate (1:3:3); Inosine, compd. with 1-(dimethylamino)-2-propanol 4-(acetylamino)benzoate (salt) (1:3); Aviral; Delimmun; Groprinosin; Immunovir; Imunovir; Inosine acedobene dimepranol; Inosine pranobex; Inosiplex; Isoprinosin; Methisoprinol; Metyzoprynol; Modimmunal; NP 113; NPT 10381; Pranosina; Pranosine; Viruxan

Inosine

Description: Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond.

CAT: BRP-00191

CAS: 58-63-9

Molecular Formula: C10H12N4O5

Molecular Weight: 268.23

Purity: ≥98% by HPLC

Appearance: White Crystalline Powder

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Storage: Store at -20°C

Density: 2.1±0.1 g/cm3

Melting Point: 207-210°C

Boiling Point: 670.5±65.0°C at 760 mmHg

Flash Point: 397°C

Application: coenzymes

Symbol: I

InChIKey: UGQMRVRMYYASKQ-KQYNXXCUSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)CO)O)O

IUPAC Name: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6-,7-,10-/m1/s1

Synonyms: 1,9-Dihydro-9-β-D-ribofuranosyl-6H-purin-6-one; 9-β-D-Ribofuranosylhypoxanthine; Hypoxanthine 9-β-D-ribofuranoside; Hypoxanthine Ribonucleoside; Hypoxanthine Riboside; Hypoxanthosine; Ribonosine; Atorel; Oxiamin; Trophicardyl; Selfer; ribo Inosine; HXR; Ino; Inosie; NSC 20262

2'-O-Methyl-5-methyluridine

Description: 2'-O-Methyl-5-methyluridine is a nucleoside analogue used in the development of antiviral drugs and anticancer agents. It has shown inhibitory activity against hepatitis C virus (HCV) and respiratory syncytial virus (RSV). It also acts as a potential target for cancer therapy due to its involvement in the regulation of cell growth and proliferation.

CAT: BRP-00192

CAS: 55486-09-4

Molecular Formula: C11H16N2O6

Molecular Weight: 272.26

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at -20°C under inert atmosphere

Density: 1.47±0.1 g/cm3 (Predicted)

Melting Point: 183-186°C

Symbol: m⁵Um

InChIKey: YHRRPHCORALGKQ-FDDDBJFASA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Sonicated)

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)OC

IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C11H16N2O6/c1-5-3-13(11(17)12-9(5)16)10-8(18-2)7(15)6(4-14)19-10/h3,6-8,10,14-15H,4H2,1-2H3,(H,12,16,17)/t6-,7-,8-,10-/m1/s1

Synonyms: 5-Methyl-2'-O-methyluridine; 2'-O-Methylribothymidine; 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 5,2'-O-Dimethyluridine; 1-(2-O-Methyl-beta-D-ribofuranosyl)thymine

5-Methyluridine

Description: 5-Methyl-uridine is an urinary nucleoside used as biological marker for the treatment of colorectal cancer. It is also a primary degradation product of tRNA.

CAT: BRP-00193

CAS: 1463-10-1

Molecular Formula: C10H14N2O6

Molecular Weight: 258.23

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at -20°C

Density: 1.576±0.06 g/cm3 (Predicted)

Melting Point: 183-185°C

Symbol: m⁵U

InChIKey: DWRXFEITVBNRMK-JXOAFFINSA-N

Solubility: Soluble in Methanol (Slightly, Heated, Sonicated), Water (Sparingly, Sonicated)

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1

Synonyms: Uridine, 5-methyl-; Ribothymidine; Thymine riboside; 1-β-D-Ribofuranosylthymine; 5-Methyl-1-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

Spongouridine

Description: 1-β-D-Arabinofuranosyluracil is an antiviral agent. It is used for the treatment of severe acute respiratory syndrome (SARS). It is also an impurity of Cytarabine.

CAT: BRP-00194

CAS: 3083-77-0

Molecular Formula: C9H12N2O6

Molecular Weight: 244.20

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: Store at -20 °C

Density: 1.674±0.06 g/cm3

Melting Point: 209-216 °C

InChIKey: DRTQHJPVMGBUCF-CCXZUQQUSA-N

Solubility: Soluble in Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7+,8-/m1/s1

Synonyms: Arauridine; 1-(β-D-Arabinofuranosyl)uracil; Uracil-1-β-D-arabinofuranoside; 1-β-D-Arabinofuranosyl-2,4(1H,3H)-pyrimidinedione; Ara-U; Arabinosyluracil; NSC 68928; Cytarabine Impurity A; Cytarabine EP Impurity A; 1-β-D-Arabinofuranosylpyrimidine-2,4(1H,3H)-dione; 1-β-D-Arabinofuranosyluracil; Arabinofuranosyluracil; Spongouridin; Uracil arabinoside; Uracil β-D-arabinofuranoside

Guanosine

Description: Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.

CAT: BRP-00196

CAS: 118-00-3

Molecular Formula: C10H13N5O5

Molecular Weight: 283.24

Purity: ≥95%

Appearance: White to Light Yellow Powder

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Storage: Store at 2-8°C (under dark)

Density: 2.25±0.1 g/cm3

Melting Point: 239°C (dec.)

Boiling Point: 775.9±70.0°C at 760 mmHg

Flash Point: 423.1°C

InChIKey: NYHBQMYGNKIUIF-UUOKFMHZSA-N

Solubility: Soluble in Water

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)NC(=NC2=O)N

IUPAC Name: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1

Synonyms: 2-Amino-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-D-ribofuranosyl-; DL-Guanosine; Guanine ribonucleoside; Guanine, 9-β-D-ribofuranosyl-; Inosine, 2-amino-; NSC 19994; Vernine; β-D-Ribofuranoside, guanine-9; ribo Guanosine

Related CAS: 141433-61-6 (hydrate) ; 85-30-3 (Deleted CAS) ; 484-80-0 (Deleted CAS) ; 685891-87-6 (Deleted CAS) ; 1022900-70-4 (Deleted CAS)

Cytarabine hydrochloride

Description: Cytarabine, an antimetabolite analogue of cytidine with a modified sugar moiety, is an antimetabolic agent and DNA synthesis inhibitor.

CAT: BRP-00197

CAS: 69-74-9

Molecular Formula: C9H14ClN3O5

Molecular Weight: 279.68

Purity: 95%

Appearance: White powder

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Storage: Store at -20 °C

Melting Point: 197-198 °C

Flash Point: 283.8°C

Shelf Life: As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly

InChIKey: KCURWTAZOZXKSJ-JBMRGDGGSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O.Cl

IUPAC Name: 4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one;hydrochloride

InChI: InChI=1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1

Synonyms: Cytosine arabinoside hydrochloride; 1-beta-D-Arabinofuranosylcytosine hydrochloride; Aracytidine hydrochloride; 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone hydrochloride; Arabinocytidine hydrochloride; Arabinofuranosylcytosine hydrochloride

Related CAS: 147-94-4 (free base)