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5'-O-DMT-2'-O-hexadecyl-N6-benzoyladenosine

Description: 5'-O-DMT-2'-O-hexadecyl-N6-benzoyladenosine is a modified adenosine derivative in which the 5'-hydroxyl is protected with a 4,4'-dimethoxytrityl (DMT) group, the 2'-hydroxyl is substituted with a long-chain hexadecyl group, and the exocyclic N6-amino group is protected with a benzoyl group. It is used as a building block in oligonucleotide synthesis to introduce hydrophobic modifications, improving membrane association, stability, and potential delivery properties of nucleic acid therapeutics.
CAT: BRP-02754
CAS: 2382942-34-7
Molecular Formula: C54H67N5O7
Molecular Weight: 898.14
Purity: ≥95%
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Density: 1.18±0.1 g/cm3
InChIKey: RGWHAZWLGXZMBX-YNCYVDIXSA-N
CanonicalSMILES: CCCCCCCCCCCCCCCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-hexadecoxy-4-hydroxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C54H67N5O7/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-23-36-64-49-48(60)46(66-53(49)59-39-57-47-50(55-38-56-51(47)59)58-52(61)40-24-19-17-20-25-40)37-65-54(41-26-21-18-22-27-41,42-28-32-44(62-2)33-29-42)43-30-34-45(63-3)35-31-43/h17-22,24-35,38-39,46,48-49,53,60H,4-16,23,36-37H2,1-3H3,(H,55,56,58,61)/t46-,48-,49-,53-/m1/s1
Synonyms: N6-Bz-5'-O-DMTr-2'-O-hexadecanyladenosine; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-hexadecyl-; 5'-O-DMTr-2'-O-C16-rA(Bz); N6-Benzoyl-5'-O-DMTr-2'-O-hexadecanyladenosine; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(hexadecyloxy)-4-hydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

N4-Bz-5'-O-DMTr-2'-O-hexadecanylcytidine

Description: N4-Bz-5'-O-DMTr-2'-O-hexadecanylcytidine is a modified cytidine nucleoside carrying an N4-benzoyl protective group, a 5'-O-dimethoxytrityl (DMTr) protecting group, and a hydrophobic hexadecyl chain attached at the 2'-position. It is used in oligonucleotide synthesis to introduce hydrophobic modifications that improve nuclease resistance, enhance membrane interaction, and increase circulation stability for potential therapeutic applications.
CAT: BRP-02755
Molecular Formula: C53H67N3O8
Molecular Weight: 874.13
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InChIKey: HPASQTWUTFVJBU-XFPIFJNBSA-N
CanonicalSMILES: O[C@@H]([C@H]([C@@H]1N2C(N=C(NC(C3=CC=CC=C3)=O)C=C2)=O)OCCCCCCCCCCCCCCCC)[C@H](O1)COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(hexadecyloxy)-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide
InChI: InChI=1S/C53H67N3O8/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-23-38-62-49-48(57)46(64-51(49)56-37-36-47(55-52(56)59)54-50(58)40-24-19-17-20-25-40)39-63-53(41-26-21-18-22-27-41,42-28-32-44(60-2)33-29-42)43-30-34-45(61-3)35-31-43/h17-22,24-37,46,48-49,51,57H,4-16,23,38-39H2,1-3H3,(H,54,55,58,59)/t46-,48-,49-,51-/m1/s1
Synonyms: 5'-DMT-2'-O-hexadecyl-N4-benzoylcytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-hexadecylcytidine; 5'-O-DMTr-2'-O-C16-rC(Bz)

5'-O-DMT-2'-O-hexadecyl-N4-acetylcytidine

Description: 5'-O-DMT-2'-O-hexadecyl-N4-acetylcytidine is a modified cytidine nucleoside featuring a 5'-O-dimethoxytrityl (DMT) protecting group, an N4-acetyl protection on the cytosine base, and a hydrophobic hexadecyl chain at the 2'-position. It is applied in oligonucleotide synthesis to enhance stability, promote hydrophobic interactions, and improve cellular uptake in nucleic acid therapeutics and delivery systems.
CAT: BRP-02756
CAS: 2382942-37-0
Molecular Formula: C48H65N3O8
Molecular Weight: 812.05
Purity: ≥98%
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Density: 1.14±0.1 g/cm3
InChIKey: NVPKBRYJGKVRFL-KYJNYJMBSA-N
CanonicalSMILES: O[C@@H]([C@H]([C@@H]1N2C(N=C(NC(C)=O)C=C2)=O)OCCCCCCCCCCCCCCCC)[C@H](O1)COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5
IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(hexadecyloxy)-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
InChI: InChI=1S/C48H65N3O8/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-21-34-57-45-44(53)42(59-46(45)51-33-32-43(49-36(2)52)50-47(51)54)35-58-48(37-22-19-18-20-23-37,38-24-28-40(55-3)29-25-38)39-26-30-41(56-4)31-27-39/h18-20,22-33,42,44-46,53H,5-17,21,34-35H2,1-4H3,(H,49,50,52,54)/t42-,44-,45-,46-/m1/s1
Synonyms: Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-hexadecyl-; N4-Ac-5'-O-DMTr-2'-O-hexadecanylcytidine; 5'-DMT-2'-O-hexadecyl-N4-acetylcytidine; 5'-O-DMTr-2'-O-C16-rC(Ac); N4-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-hexadecylcytidine

5'-O-DMT-2'-O-hexadecyl-N2-isobutyrylguanosine

Description: 5'-O-DMT-2'-O-hexadecyl-N2-isobutyrylguanosine is a modified guanosine derivative where the 5'-hydroxyl is protected with a 4,4'-dimethoxytrityl (DMT) group, the 2'-hydroxyl is substituted with a hydrophobic hexadecyl chain, and the N2 position of guanine is protected with an isobutyryl group. It is used in oligonucleotide synthesis to introduce hydrophobic modifications, enhancing membrane interaction, stability, and delivery potential in nucleic acid–based therapeutics.
CAT: BRP-02757
CAS: 2382942-31-4
Molecular Formula: C51H69N5O8
Molecular Weight: 880.14
Purity: ≥98%
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Density: 1.19±0.1 g/cm3
InChIKey: PJMOFQPOUATKHV-WBGRFHBGSA-N
CanonicalSMILES: CCCCCCCCCCCCCCCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)NC(=O)C(C)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-hexadecoxy-4-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C51H69N5O8/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-22-33-62-45-44(57)42(64-49(45)56-35-52-43-46(56)53-50(55-48(43)59)54-47(58)36(2)3)34-63-51(37-23-20-19-21-24-37,38-25-29-40(60-4)30-26-38)39-27-31-41(61-5)32-28-39/h19-21,23-32,35-36,42,44-45,49,57H,6-18,22,33-34H2,1-5H3,(H2,53,54,55,58,59)/t42-,44-,45-,49-/m1/s1
Synonyms: N2-iBu-5'-O-DMTr-2'-O-hexadecanyl guanosine; N2-iBu-5'-O-DMTr-2'-O-hexadecanylguanosine; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-hexadecyl-N-(2-methyl-1-oxopropyl)-; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-hexadecyl-N-isobutyrylguanosine; 5'-O-DMTr-2'-O-C16-rG(iBu); N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(hexadecyloxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

5'-O-DMT-2'-O-hexadecyluridine

Description: 5'-O-DMT-2'-O-hexadecyluridine is a modified uridine nucleoside bearing a 5'-O-dimethoxytrityl (DMT) protecting group and a long hydrophobic hexadecyl chain at the 2'-position. It is used in oligonucleotide synthesis to introduce hydrophobic modifications that enhance membrane interactions, improve stability, and facilitate delivery in nucleic acid therapeutics.
CAT: BRP-02758
CAS: 2382942-76-7
Molecular Formula: C46H62N2O8
Molecular Weight: 771.01
Purity: ≥98%
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Density: 1.18±0.1 g/cm3
InChIKey: JYFRYIKQCNCSAI-QQIQMRLBSA-N
CanonicalSMILES: CCCCCCCCCCCCCCCCO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O
IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-hexadecoxy-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C46H62N2O8/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-20-33-54-43-42(50)40(56-44(43)48-32-31-41(49)47-45(48)51)34-55-46(35-21-18-17-19-22-35,36-23-27-38(52-2)28-24-36)37-25-29-39(53-3)30-26-37/h17-19,21-32,40,42-44,50H,4-16,20,33-34H2,1-3H3,(H,47,49,51)/t40-,42-,43-,44-/m1/s1
Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-hexadecyl-; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(hexadecyloxy)-4-hydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-DMTr-2'-O-C16-rU; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-hexadecyluridine

N4-Bz-5-methyl-5'-O-DMTr-2'-O-hexadecanylcytidine

Description: N4-Bz-5-methyl-5'-O-DMTr-2'-O-hexadecanylcytidine is a cytidine derivative featuring a 5-methyl substitution on the base, N4-benzoyl protection, a 5'-O-dimethoxytrityl (DMTr) protecting group, and a hydrophobic hexadecyl chain at the 2'-position. It is employed in oligonucleotide synthesis to introduce methylated and hydrophobic cytosine residues, enhancing nucleic acid stability, base-pairing modulation, and lipophilic properties for improved biological performance.
CAT: BRP-02759
Molecular Formula: C54H69N3O8
Molecular Weight: 888.16
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InChIKey: SLHQEAWOHAKSBL-PRCACPCUSA-N
CanonicalSMILES: O[C@@H]([C@H]([C@@H]1N2C(N=C(NC(C3=CC=CC=C3)=O)C(C)=C2)=O)OCCCCCCCCCCCCCCCC)[C@H](O1)COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(hexadecyloxy)-4-hydroxytetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide
InChI: InChI=1S/C54H69N3O8/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-24-37-63-49-48(58)47(65-52(49)57-38-40(2)50(56-53(57)60)55-51(59)41-25-20-18-21-26-41)39-64-54(42-27-22-19-23-28-42,43-29-33-45(61-3)34-30-43)44-31-35-46(62-4)36-32-44/h18-23,25-36,38,47-49,52,58H,5-17,24,37,39H2,1-4H3,(H,55,56,59,60)/t47-,48-,49-,52-/m1/s1
Synonyms: 5'-O-DMTr-2'-O-C16-5-Me-rC(Bz); 5'-DMT-2'-O-hexadecyl-N4-benzoyl-5-methylcytidine; N4-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-hexadecyl-5-methylcytidine; N4-Benzoyl-5'-O-DMTr-2'-O-hexadecanyl-5-methylcytidine

5'-O-DMT-2'-O-hexadecyl-5-methyluridine

Description: 5'-O-DMT-2'-O-hexadecyl-5-methyluridine is a modified nucleoside featuring a 5'-O-dimethoxytrityl (DMT) protecting group, a hydrophobic hexadecyl chain at the 2'-position, and a 5-methyl substitution on uridine. It is employed in oligonucleotide synthesis to enhance nuclease resistance, improve hydrophobic interactions, and increase stability and delivery efficiency in nucleic acid therapeutics.
CAT: BRP-02760
Molecular Formula: C47H64N2O8
Molecular Weight: 785.04
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InChIKey: YKKIIVRJFCKUPJ-QFYXQNDISA-N
CanonicalSMILES: O[C@@H]([C@H]([C@@H]1N2C(NC(C(C)=C2)=O)=O)OCCCCCCCCCCCCCCCC)[C@H](O1)COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5
IUPAC Name: 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(hexadecyloxy)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
InChI: InChI=1S/C47H64N2O8/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-21-32-55-43-42(50)41(57-45(43)49-33-35(2)44(51)48-46(49)52)34-56-47(36-22-19-18-20-23-36,37-24-28-39(53-3)29-25-37)38-26-30-40(54-4)31-27-38/h18-20,22-31,33,41-43,45,50H,5-17,21,32,34H2,1-4H3,(H,48,51,52)/t41-,42-,43-,45-/m1/s1
Synonyms: 5'-O-DMTr-2'-O-hexadecanylthymine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-hexadecyl-5-methyluridine; 5'-O-DMTr-2'-O-C16-5-Me-rU; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-hexadecylthymine; 5'-O-DMTr-2'-O-C16-rT

N2-DMF-5'-O-DMTr-2'-O-hexadecanylguanosine

Description: N2-DMF-5'-O-DMTr-2'-O-hexadecanylguanosine is a guanosine derivative where the N2 position is protected with a dimethylformamidine (DMF) group, the 5'-hydroxyl is protected with a 4,4'-dimethoxytrityl (DMTr) group, and the 2'-hydroxyl is substituted with a hydrophobic hexadecyl chain. It is used in oligonucleotide synthesis to incorporate hydrophobic and chemically protected guanosine residues, improving stability, lipophilicity, and delivery properties of modified nucleic acids.
CAT: BRP-02761
Molecular Formula: C50H68N6O7
Molecular Weight: 865.13
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InChIKey: CBLRPVPEFZTXQX-WLOZIAGUSA-N
CanonicalSMILES: O[C@@H]([C@H]([C@@H]1N2C(N=C(N=CN(C)C)NC3=O)=C3N=C2)OCCCCCCCCCCCCCCCC)[C@H](O1)COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
IUPAC Name: N'-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(hexadecyloxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide
InChI: InChI=1S/C50H68N6O7/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-22-33-61-45-44(57)42(63-48(45)56-36-51-43-46(56)53-49(54-47(43)58)52-35-55(2)3)34-62-50(37-23-20-19-21-24-37,38-25-29-40(59-4)30-26-38)39-27-31-41(60-5)32-28-39/h19-21,23-32,35-36,42,44-45,48,57H,6-18,22,33-34H2,1-5H3,(H,53,54,58)/t42-,44-,45-,48-/m1/s1
Synonyms: N2-DMF-5'-O-DMTr-2'-O-hexadecanyl guanosine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-hexadecanyl-N2-DMF-Guanosine; 5'-O-DMT-2'-O-C16-N2-DMF-rG; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-hexadecanyl-N-[(dimethylamino)methylene]guanosine; 5'-O-DMT-2'-O-C16-rG(DMF)

5'-O-DMTr-2'-O-Propargyl-rC(Bz)

Description: 5'-O-DMTr-2'-O-Propargyl-rC(Bz) is a ribonucleoside derivative bearing a 5'-O-dimethoxytrityl (DMTr) protecting group, a 2'-O-propargyl substituent, and an N4-benzoyl-protected cytidine base. It is used in oligonucleotide synthesis, where the propargyl group enables click chemistry conjugation with azides for biolabeling, probe design, or functional nucleic acid development.
CAT: BRP-02762
CAS: 171486-52-5
Molecular Formula: C40H37N3O8
Molecular Weight: 687.74
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Density: 1.24±0.1 g/cm3
InChIKey: DXNRMSDLGCHDTN-XHOUGWTJSA-N
CanonicalSMILES: O[C@H]1[C@@H](OCC#C)[C@H](N(C=CC(NC(C2=CC=CC=C2)=O)=N3)C3=O)O[C@@H]1COC(C4=CC=C(OC)C=C4)(C5=CC=CC=C5)C6=CC=C(OC)C=C6
IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide
InChI: InChI=1S/C40H37N3O8/c1-4-25-49-36-35(44)33(51-38(36)43-24-23-34(42-39(43)46)41-37(45)27-11-7-5-8-12-27)26-50-40(28-13-9-6-10-14-28,29-15-19-31(47-2)20-16-29)30-17-21-32(48-3)22-18-30/h1,5-24,33,35-36,38,44H,25-26H2,2-3H3,(H,41,42,45,46)/t33-,35-,36-,38-/m1/s1
Synonyms: Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propyn-1-yl-; N4-Bz-5'-O-DMT-2'-O-propargyl-Cr; N4-Bz-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-cytidine; N4-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-propyn-1-yl)cytidine; 5'-O-DMTr-2'-O-PA-C(Bz)

5'-O-DMTr-2'-O-Propargyl-5-Me-rC(Bz)

Description: 5'-O-DMTr-2'-O-Propargyl-5-Me-rC(Bz) is a ribonucleoside derivative in which 5-methylcytidine carries a 5'-O-dimethoxytrityl (DMTr) protecting group, a 2'-O-propargyl substituent, and an N4-benzoyl (Bz)–protected base. This compound is used in oligonucleotide synthesis to introduce a reactive alkyne handle for click chemistry, enabling bioconjugation, labeling, or functional modification of RNA molecules.
CAT: BRP-02763
Molecular Formula: C41H39N3O8
Molecular Weight: 701.78
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InChIKey: WORIBDVDBITLJE-LZURGKRNSA-N
CanonicalSMILES: O[C@H]1[C@@H](OCC#C)[C@H](N(C=C(C)C(NC(C2=CC=CC=C2)=O)=N3)C3=O)O[C@@H]1COC(C4=CC=C(OC)C=C4)(C5=CC=CC=C5)C6=CC=C(OC)C=C6
IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide
InChI: InChI=1S/C41H39N3O8/c1-5-24-50-36-35(45)34(52-39(36)44-25-27(2)37(43-40(44)47)42-38(46)28-12-8-6-9-13-28)26-51-41(29-14-10-7-11-15-29,30-16-20-32(48-3)21-17-30)31-18-22-33(49-4)23-19-31/h1,6-23,25,34-36,39,45H,24,26H2,2-4H3,(H,42,43,46,47)/t34-,35-,36-,39-/m1/s1
Synonyms: Cytidine, 5-methyl-N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propyn-1-yl-; N4-Bz-5'-O-DMT-2'-O-propargyl-5-Me-Cr; N4-Bz-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-5-methylcytidine; N4-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-propyn-1-yl)-5-methylcytidine; 5'-O-DMTr-2'-O-PA-5-MeC(Bz)

5'-O-DMT-2'-O-propargyl-N2-dimethylformamidine-guanosine

Description: 5'-O-DMT-2'-O-propargyl-N2-dimethylformamidine-guanosine is a guanosine derivative in which the 5'-hydroxyl is protected with a dimethoxytrityl (DMT) group, the 2'-hydroxyl carries a propargyl substituent, and the N2 position of guanine is protected with a dimethylformamidine (dmf) group. This compound is used in oligonucleotide synthesis to introduce a reactive alkyne handle for click chemistry, allowing site-specific bioconjugation, labeling, or functional modification of RNA and DNA molecules.
CAT: BRP-02764
CAS: 210096-45-0
Molecular Formula: C37H38N6O7
Molecular Weight: 678.74
Purity: ≥98%
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Density: 1.295±0.14 g/cm3
InChIKey: DYMNGWMGTJHXNI-GNEJCJDASA-N
CanonicalSMILES: CN(C)/C=N/C1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OCC#C
IUPAC Name: N'-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-prop-2-ynoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide
InChI: InChI=1S/C37H38N6O7/c1-6-20-48-32-31(44)29(50-35(32)43-23-38-30-33(43)40-36(41-34(30)45)39-22-42(2)3)21-49-37(24-10-8-7-9-11-24,25-12-16-27(46-4)17-13-25)26-14-18-28(47-5)19-15-26/h1,7-19,22-23,29,31-32,35,44H,20-21H2,2-5H3,(H,40,41,45)/b39-22+/t29-,31-,32-,35-/m1/s1
Synonyms: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-2-propynyl-; N'-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide; N2-DMF-5'-O-DMT-2'-O-propargyl-Gr; N2-DMF-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-guanosine; N2-Dimethylformamide-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-propyn-1-yl)guanosine; 5'-O-DMTr-2'-O-PA-G(DMF)
* Only for research. Not suitable for any diagnostic or therapeutic use.

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