What are nucleosides used for?

Nucleosides are base molecules used as starting materials for synthesizing nucleotides and phosphoramidites.

What is the difference between nucleosides and nucleotides?

Nucleosides lack phosphate groups, while nucleotides contain one or more phosphates required for enzymatic reactions.

Are nucleosides used directly in enzymatic reactions?

Nucleosides are typically chemically modified before being used in enzymatic workflows.

Can nucleosides be chemically modified?

Yes, modified nucleosides are widely used to introduce structural or functional changes in nucleic acids.

Why is nucleoside purity important?

High purity ensures correct downstream synthesis of nucleotides and phosphoramidites with predictable performance.

Nucleosides - BOC Sciences

2-Acetamido-6-chloro-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine

Description: 2-Acetamido-6-chloro-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a remarkable antiviral compound, showing potential in combating a range of viral infections. By impeding viral replication and augmenting immune responses, this compound manifests as a promising tool against afflictions caused by herpes simplex virus and human immunodeficiency virus (HIV).

CAT: BRP-01913

CAS: 137896-02-7

Molecular Formula: C18H20ClN5O8

Molecular Weight: 469.83

Purity: 95%

Appearance: Light Orange Solid

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Storage: Store at -20°C

Density: 1.63±0.1 g/cm3 (Predicted)

Melting Point: 71-73 °C

InChIKey: OVXYEIBYTBNNFE-LSCFUAHRSA-N

Solubility: Soluble in Acetone, Chloroform, Methanol

SMILES: CC(=O)NC1=NC2=C(C(=N1)Cl)N=CN2C3C(C(C(O3)COC(=O)C)OC(=O)C)OC(=O)C

IUPAC Name: [(2R,3R,4R,5R)-5-(2-acetamido-6-chloropurin-9-yl)-3,4-diacetyloxyoxolan-2-yl]methyl acetate

InChI: InChI=1S/C18H20ClN5O8/c1-7(25)21-18-22-15(19)12-16(23-18)24(6-20-12)17-14(31-10(4)28)13(30-9(3)27)11(32-17)5-29-8(2)26/h6,11,13-14,17H,5H2,1-4H3,(H,21,22,23,25)/t11-,13-,14-,17-/m1/s1

Synonyms: N-[6-Chloro-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-9H-purin-2-yl]acetamide; (2R,3R,4R,5R)-2-(2-acetamido-6-chloro-9H-purin-9-yl)-5-(acetoxymethyl)tetrahydrofuran-3,4-diyl diacetate

5'-Amino-5'-deoxy-2',3'-O-(1-methylethylidene)-adenosine

Description: 5'-Amino-5'-deoxy-2',3'-O-(1-methylethylidene)-adenosine, an exceptionally potent nucleoside analogue, exhibits remarkable antiviral characteristics. Its application in the biomedical sector revolves around combatting viral infections, primarily those necessitating adenosine for replication. An impressive attribute of this substance lies in its ability to impede viral replication by derailing the intricate viral RNA synthesis pathway, rendering it highly efficacious against an extensive spectrum of viral ailments.

CAT: BRP-01914

CAS: 21950-36-7

Molecular Formula: C13H18N6O3

Molecular Weight: 306.32

Purity: 98%

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Storage: Store at 2-8 °C, protect from light

Density: 1.80±0.1 g/cm3

Melting Point: 202-203 °C

Boiling Point: 553.1±60.0 °C at 760 mmHg

InChIKey: RGJLVQRLOVOJRF-WOUKDFQISA-N

SMILES: CC1(OC2C(OC(C2O1)N3C=NC4=C(N=CN=C43)N)CN)C

IUPAC Name: 9-[(3aR,4R,6R,6aR)-6-(aminomethyl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]purin-6-amine

InChI: InChI=1S/C13H18N6O3/c1-13(2)21-8-6(3-14)20-12(9(8)22-13)19-5-18-7-10(15)16-4-17-11(7)19/h4-6,8-9,12H,3,14H2,1-2H3,(H2,15,16,17)/t6-,8-,9-,12-/m1/s1

Synonyms: 9-[(3aR,4R,6R,6aR)-6-(aminomethyl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]-9H-purin-6-amine; Adenosine, 5'-amino-5'-deoxy-2',3'-O-(1-methylethylidene)-; 5'-Amino-5'-deoxy-2',3'-O-isopropylidineadenosine

6-Aza-2-thiouridine

Description: 6-Aza-2-thiouridine is a remarkable compound with profound antiviral effects, exhibiting exceptional inhibitory potency against a myriad of RNA viruses encompassing Influenza A and the notorious Zika virus. Its formidable prowess resides in its unrivaled disruption of viral RNA research and development, unequivocally dismantling the intricate replication machinery.

CAT: BRP-01915

CAS: 27089-56-1

Molecular Formula: C8H11N3O5S

Molecular Weight: 261.26

Purity: 98%

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Storage: Store at 2-8 °C, stored under nitrogen

Density: 2.02±0.1 g/cm3

Melting Point: 201-203 °C

InChIKey: TVCBDTCUOVDLNZ-SHUUEZRQSA-N

SMILES: C1=NN(C(=S)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-sulfanylidene-1,2,4-triazin-5-one

InChI: InChI=1S/C8H11N3O5S/c12-2-3-5(14)6(15)7(16-3)11-8(17)10-4(13)1-9-11/h1,3,5-7,12,14-15H,2H2,(H,10,13,17)/t3-,5-,6-,7-/m1/s1

Synonyms: 2-Thio-6-azauridine; 3,4-Dihydro-2-β-D-ribofuranosyl-3-thioxo-1,2,4-triazin-5(2H)-one; as-Triazine-3,5(2H,4H)-dione, 2-β-D-ribofuranosyl-3-thio-; 1-β-D-Ribofuranosyl-2-thio-6-azauracil

2-O-Methyl-5-methyluridine

Description: 2-O-Methyl-5-methyluridine is an indispensable compound with potential antiviral and anticancer activities.

CAT: BRP-01916

CAS: 114952-97-5

Molecular Formula: C11H16N2O6

Molecular Weight: 272.25

Purity: ≥95%

Appearance: White to off-white powder

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Density: 1.61±0.1 g/cm3

Boiling Point: 485.4±55.0°C at 760 mmHg

InChIKey: LTVSTRRNQLBTBJ-FDDDBJFASA-N

SMILES: CC1=CN(C(=NC1=O)OC)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-methoxy-5-methylpyrimidin-4-one

InChI: InChI=1S/C11H16N2O6/c1-5-3-13(11(18-2)12-9(5)17)10-8(16)7(15)6(4-14)19-10/h3,6-8,10,14-16H,4H2,1-2H3/t6-,7-,8-,10-/m1/s1

Synonyms: Uridine, 5-methyl-2-O-methyl-; 5-Methyl-2-O-methyl-uridine; 2-Methoxy-5-methyl-1-(β-D-ribofuranosyl)-4(1H)-pyrimidinone; 4(1H)-Pyrimidinone, 2-methoxy-5-methyl-1-β-D-ribofuranosyl-; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-methoxy-5-methylpyrimidin-4(1H)-one

Related CAS: 55486-09-4 (5-Methyl-2'-O-methyluridine)

8-Aminoguanosine

Description: A potent inhibitor of purine nucleoside phosphorylase.

CAT: BRP-01917

CAS: 3868-32-4

Molecular Formula: C10H14N6O5

Molecular Weight: 298.26

Purity: 98%

Appearance: Off-White to Tan Solid

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Storage: Store at -20 °C, under inert atmosphere

Density: 2.44±0.1 g/cm3

Melting Point: >240 °C (dec.)

InChIKey: FNXPTCITVCRFRK-UMMCILCDSA-N

Solubility: Soluble in Hot DMSO, Hot Water

SMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O

IUPAC Name: 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1

Synonyms: Inosine, 2,8-diamino-; NSC 90390; 2,8-Diaminoinosine; 2,8-diamino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one

6-Chloroguanine riboside

Description: 6-Chloroguanine riboside is a novel inhibitor of endogenous protein degradation. 6-Chloroguanine riboside is a modified nucleoside with a chlorine atom at the 6-position of the guanine base. It is used in biochemical and pharmacological research to study nucleic acid structure and function, mutagenesis, and potential therapeutic applications, including antiviral and anticancer activities.

CAT: BRP-01919

CAS: 2004-07-1

Molecular Formula: C10H12ClN5O4

Molecular Weight: 301.69

Purity: ≥97% by HPLC

Appearance: White Powder

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Storage: Store at -20°C

Density: 2.19 g/cm3

Melting Point: 171-172 °C (dec.)

Boiling Point: 729.9±70.0 °C at 760 mmHg

InChIKey: TXWHPSZYRUHEGT-UUOKFMHZSA-N

Solubility: Soluble in DMSO, Methanol

SMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(N=C2Cl)N

IUPAC Name: (2R,3R,4S,5R)-2-(2-amino-6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H12ClN5O4/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1

Synonyms: 6-Chloroguanosine; 2-Amino-6-chloro-9-(β-D-ribofuranosyl)-purine; 6-Chloro-9-β-D-ribofuranosyl-9H-purin-2-amine; 2-Amino-6-chloropurine Ribonucleoside; 2-Amino-6-chloropurine Riboside; NSC 44586; (2R,3R,4S,5R)-2-(2-Amino-6-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

(E)-N'-(9-((2R,3R,4R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide

Description: (E)-N'-(9-((2R,3R,4R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide, a novel molecule with potential applications in cancer therapy, has been shown to act by selectively inhibiting certain proteins critical to cancer cell proliferation and survival. Studies performed in preclinical models demonstrated promising results, and efforts to further develop this compound are currently underway. Defining a precise mechanism of action will require more detailed studies of this complex therapeutic candidate.

CAT: BRP-01921

Molecular Formula: C40H50N6O7Si

Molecular Weight: 754.95

Purity: 98%

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Density: 1.2±0.1 g/cm3

InChIKey: QLIITSYHYKRUSO-NZMSPFHGSA-N

SMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N=CN(C)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: N'-[9-[(2R,3R,4R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide

InChI: InChI=1S/C40H50N6O7Si/c1-39(2,3)54(8,9)53-34-33(47)31(52-37(34)46-25-41-32-35(46)43-38(44-36(32)48)42-24-45(4)5)23-51-40(26-13-11-10-12-14-26,27-15-19-29(49-6)20-16-27)28-17-21-30(50-7)22-18-28/h10-22,24-25,31,33-34,37,47H,23H2,1-9H3,(H,43,44,48)/b42-24+/t31?,33-,34-,37-/m1/s1

Synonyms: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, (4ξ)-; (4ξ)-5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-N-[(dimethylamino)methylen]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]guanosine

Related CAS: 126922-61-0 (2'-O-(t-Butyldimethylsilyl)-N-(dimethylaminomethylene)-5'-O-(4,4'-dimethoxytrityl)guanosine)

2'-O-(t-Butyldimethylsilyl)-N-(dimethylaminomethylene)-5'-O-(4,4'-dimethoxytrityl)guanosine

Description: 2'-O-(t-Butyldimethylsilyl)-N-(dimethylaminomethylene)-5'-O-(4,4'-dimethoxytrityl)guanosine is a crucial intermediate in the chemical synthesis of RNA oligonucleotides. The protecting groups ensure the correct assembly of RNA sequences by preventing unwanted side reactions. This compound is widely used in biochemical research and therapeutic development, particularly in studies involving RNA structure and function.

CAT: BRP-01922

CAS: 126922-61-0

Molecular Formula: C40H50N6O7Si

Molecular Weight: 754.95

Purity: 95%

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Storage: Store at 2-8 °C

Density: 1.23±0.1 g/cm3

InChIKey: QLIITSYHYKRUSO-SPBWOXKUSA-N

SMILES: CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N=CN(C)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: N'-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide

Synonyms: 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]guanosine; 5'-O-DMT-2'-O-TBDMS-N2-dimethylformamidine-guanosine; 5'-O-DMT-2'-O-TBDMS-G(DMF)

5'-Acetyl-2',3'-isopropylidene Adenosine

Description: 5'-Acetyl-2',3'-isopropylidene Adenosine, a highly advanced and multifunctional bioactive compound, plays a pivotal role in the realm of cutting-edge biomedical research.

CAT: BRP-01923

CAS: 15888-38-7

Molecular Formula: C15H19N5O5

Molecular Weight: 349.34

Purity: 97%

Appearance: White Solid

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Storage: Store at -20°C

Density: 1.68±0.1 g/cm3

Melting Point: 170-172 °C

Boiling Point: 562.2±60.0 °C at 760 mmHg

InChIKey: AGPPMENETHBDES-IDTAVKCVSA-N

Solubility: Soluble in Chloroform (Slightly), Methanol (Slightly)

SMILES: CC(=O)OCC1C2C(C(O1)N3C=NC4=C3N=CN=C4N)OC(O2)(C)C

IUPAC Name: [(3aR,4R,6R,6aR)-4-(6-aminopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methyl acetate

InChI: InChI=1S/C15H19N5O5/c1-7(21)22-4-8-10-11(25-15(2,3)24-10)14(23-8)20-6-19-9-12(16)17-5-18-13(9)20/h5-6,8,10-11,14H,4H2,1-3H3,(H2,16,17,18)/t8-,10-,11-,14-/m1/s1

Synonyms: 5'-O-Acetyl-2',3'-O-isopropylideneadenosine; 2',3'-O-Isopropylidene-5'-O-acetyladenosine; 2',3'-O-(1-Methylethylidene)adenosine 5'-Acetate; NSC 90373; Adenosine, 2',3'-O-(1-methylethylidene)-, 5'-acetate; Adenosine, 2',3'-O-isopropylidene-, 5'-acetate; 5'-Acetyl-2',3'-isopropylideneadenosine

N6-p-Sulfophenyladenosine

Description: N6-p-Sulfophenyladenosine is a modified adenosine derivative used extensively in biochemical and pharmacological research. Its unique modification at the N6 position allows for the detailed study of adenosine receptor interactions, signal transduction pathways, and the development of potential therapeutic agents targeting adenosine-related pathways. The addition of the sulfophenyl group can significantly influence its binding properties and biological activities, making it a valuable tool in various research applications.

CAT: BRP-01924

CAS: 143668-15-9

Molecular Formula: C16H17N5O7S

Molecular Weight: 423.40

Purity: 98%

Appearance: Off-white solid

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Density: 1.91±0.1 g/cm3

InChIKey: ZUEJJBKBTNSMGJ-XNIJJKJLSA-N

SMILES: C1=CC(=CC=C1NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O)S(=O)(=O)O

IUPAC Name: 4-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]benzenesulfonic acid

InChI: InChI=1S/C16H17N5O7S/c22-5-10-12(23)13(24)16(28-10)21-7-19-11-14(17-6-18-15(11)21)20-8-1-3-9(4-2-8)29(25,26)27/h1-4,6-7,10,12-13,16,22-24H,5H2,(H,17,18,20)(H,25,26,27)/t10-,12-,13-,16-/m1/s1

Synonyms: Benzenesulfonic acid, 4-[(9-β-D-ribofuranosyl-9H-purin-6-yl)amino]-; N6-(p-Sulfophenyl)adenosine; 4-[(9-β-D-Ribofuranosyl-9H-purin-6-yl)amino]benzenesulfonic acid; N-(p-Sulfophenyl)adenosine

Related CAS: 1349749-05-8 (monosodium salt) ; 143668-16-0 (triethylamine salt (1:1))

6-Chloropurine Riboside

Description: 6-Chloropurine Riboside is an adenosine deaminase substrate. 6-Chloropurine Riboside is a modified nucleoside where a chlorine atom is attached to the 6-position of the purine base. It is used in biochemical research to study nucleic acid structure and function, and to investigate nucleic acid interactions. Additionally, it serves as a precursor in the synthesis of other modified nucleosides and nucleotides for therapeutic and diagnostic applications.

CAT: BRP-01926

CAS: 5399-87-1

Molecular Formula: C10H11ClN4O4

Molecular Weight: 286.67

Purity: 95%

Appearance: White to beige solid

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Storage: Store at 2-8 °C

Density: 2.03±0.1 g/cm3

Melting Point: 180-182 °C

Boiling Point: 614.8±65.0 °C at 760 mmHg

InChIKey: XHRJGHCQQPETRH-KQYNXXCUSA-N

Solubility: Soluble in DMSO (Sparingly, Heated), Methanol (Slightly, Heated), Water (Slightly, Heated)

SMILES: C1=NC2=C(C(=N1)Cl)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: (2R,3R,4S,5R)-2-(6-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H11ClN4O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2/t4-,6-,7-,10-/m1/s1

Synonyms: 6-Chloro Inosine; 6-Chloro-9-(beta-D-ribofuranosyl)purine; 6-chloroinosine; 6-Chloropurine-9-β-D-ribofuranoside; 6-Chloro-6-deaminoadenosine; 6-Chloro-9-β-D-ribofuranosyl-9H-purine; 6-Chloro-9-β-D-ribofuranosylpurine; 6-Chloronebularine; 6-Chloropurine-D-riboside; 6-Chloropurinosine; 9-(β-D-Ribofuranosyl)-6-chloropurine; NSC 4910; Chloropurine riboside

2,6-Dichloropurine-9-β-D-riboside

Description: 2,6-Dichloropurine riboside is a valuable tool in biochemical, pharmacological, and chemical biology research. Its modified structure allows scientists to study the effects of chlorine substitution on nucleotide function, enzyme interactions, and potential therapeutic applications in antiviral and anticancer treatments. This compound provides insights into the role of modified nucleosides in various biological processes and the development of novel therapeutic agents.

CAT: BRP-01927

CAS: 13276-52-3

Molecular Formula: C10H10Cl2N4O4

Molecular Weight: 321.12

Purity: 97%

Appearance: White to Off-White Solid

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Storage: Store at -20°C

Density: 2.14±0.1 g/cm3(Predicted)

Melting Point: >190°C (dec)

Boiling Point: 542.2±60.0 °C(Predicted)

InChIKey: HJXWZGVMHDPCRS-UUOKFMHZSA-N

Solubility: Soluble in Methanol, Water

SMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(N=C2Cl)Cl

IUPAC Name: (2R,3R,4S,5R)-2-(2,6-dichloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H10Cl2N4O4/c11-7-4-8(15-10(12)14-7)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2/t3-,5-,6-,9-/m1/s1

Synonyms: 2,6-Dichloropurine riboside; (2R,3R,4S,5R)-2-(2,6-Dichloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2,6-Dichloro-9-β-D-ribofuranosyl-9H-purine; Purine, 2,6-dichloro-9-β-D-ribofuranosyl-

4-Chloro-5-iodo-7-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

Description: (2R,3R,4R,5R)-2-((benzoyloxy)methyl)-5-(4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diyl dibenzoate, plays a critical role as an intermediary in the manufacture of cancer-fighting medications, specifically targeting breast, lung, and colorectal cancer. Its complex chemical composition and properties make it a valuable resource in the pharmaceutical industry.

CAT: BRP-01928

CAS: 480439-89-2

Molecular Formula: C32H23ClIN3O7

Molecular Weight: 723.90

Purity: 97%

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Storage: Store at -20 °C, stored under nitrogen

Density: 1.64±0.1 g/cm3

Boiling Point: 796.0±60.0 °C at 760 mmHg

InChIKey: WHVWNDLPQYBIGY-CTDWIVFPSA-N

SMILES: C1=CC=C(C=C1)C(=O)OCC2C(C(C(O2)N3C=C(C4=C3N=CN=C4Cl)I)OC(=O)C5=CC=CC=C5)OC(=O)C6=CC=CC=C6

IUPAC Name: [(2R,3R,4R,5R)-3,4-dibenzoyloxy-5-(4-chloro-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)oxolan-2-yl]methyl benzoate

InChI: InChI=1S/C32H23ClIN3O7/c33-27-24-22(34)16-37(28(24)36-18-35-27)29-26(44-32(40)21-14-8-3-9-15-21)25(43-31(39)20-12-6-2-7-13-20)23(42-29)17-41-30(38)19-10-4-1-5-11-19/h1-16,18,23,25-26,29H,17H2/t23-,25-,26-,29-/m1/s1

Synonyms: 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-5-iodo-7-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-; (2R,3R,4R,5R)-2-((benzoyloxy)methyl)-5-(4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-3,4-diyl dibenzoate

6-Chloropurine-9-(2,3-isopropylidene-β-D-ribofuranoside)

Description: 6-Chloropurine-9-(2,3-isopropylidene-β-D-ribofuranoside) is a protected nucleoside analog used in chemical and biochemical research. The chlorination at the 6-position of the purine base and the isopropylidene protection of the ribose sugar allow for controlled synthesis and modification of nucleosides. This compound is valuable for studying nucleotide analog interactions, enzyme mechanisms, and potential therapeutic applications in antiviral and anticancer research.

CAT: BRP-01929

CAS: 39824-26-5

Molecular Formula: C13H15ClN4O4

Molecular Weight: 326.74

Purity: 98%

Appearance: Pale Yellow Solid

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Storage: Store at -20 °C, sealed storage, away from moisture

Density: 1.79±0.1 g/cm3 (Predicted)

Melting Point: 152-155°C

Boiling Point: 527.8±60.0°C (Predicted)

InChIKey: VDYNZOUPLVQLRV-WOUKDFQISA-N

Solubility: Soluble in Chloroform (Slightly), Dichloromethane (Slightly), Diethyl Ether (Slightly), Ethanol

SMILES: CC1(OC2C(OC(C2O1)N3C=NC4=C3N=CN=C4Cl)CO)C

IUPAC Name: [(3aR,4R,6R,6aR)-4-(6-chloropurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methanol

InChI: InChI=1S/C13H15ClN4O4/c1-13(2)21-8-6(3-19)20-12(9(8)22-13)18-5-17-7-10(14)15-4-16-11(7)18/h4-6,8-9,12,19H,3H2,1-2H3/t6-,8-,9-,12-/m1/s1

Synonyms: 6-Chloro-9-(2',3'-di-O-isopropylidene-beta-D-ribofuranosyl)purine; 6-Chloro-9-β-D-(2,3-isopropylidene)ribofuranosylpurine; 6-Chloro-9-[2,3-O-(1-methylethylidene)-beta-D-ribofuranosyl]-9H-Purine; [(3aR,4R,6R,6aR)-4-(6-chloropurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methanol; 6-Chloro-9-(2,3-O-isopropylidene-β-D-ribofuranosyl)-9H-purine

6-Chloro-7-deazapurine-β-D-riboside

Description: 6-Chloro-7-deazapurine-β-D-riboside is an adenosine kinase inhibitor. 6-Chloro-7-deazapurine-β-D-riboside is a valuable nucleoside analog used in biochemical and pharmacological research. Its modified structure allows scientists to study the effects of chlorination and deaza modifications on nucleotide function, enzyme interactions, and potential therapeutic applications in antiviral and anticancer treatments. This compound provides insights into the role of modified nucleosides in various biological processes and the development of novel therapeutic agents.

CAT: BRP-01930

CAS: 16754-80-6

Molecular Formula: C11H12ClN3O4

Molecular Weight: 285.68

Purity: ≥95%

Appearance: White to Off-White Solid

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Storage: Store at 2-8 °C, stored under nitrogen

Density: 1.87±0.1 g/cm3 (Predicted)

Melting Point: 160-162°C

Boiling Point: 591.4±50.0°C (Predicted)

InChIKey: BFDDOTZWMOKUCD-UIRWVKCDSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)

SMILES: C1=CN(C2=C1C(=NC=N2)Cl)C3C(C(C(O3)CO)O)O

IUPAC Name: (2R,3R,4S,5R)-2-(4-chloropyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C11H12ClN3O4/c12-9-5-1-2-15(10(5)14-4-13-9)11-8(18)7(17)6(3-16)19-11/h1-2,4,6-8,11,16-18H,3H2/t6-,7+,8?,11-/m1/s1

Synonyms: 6-Chloro-7-deazapurine-9-b-D-ribofuranose; 4-Chloro-7-(b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine; 4-Chloro-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 6-Chloro-9-(β-D-ribofuranosyl)-7-deazapurine; 6-Deamino-6-chlorotubercidin; NSC 101161

6-Mercaptopurine Riboside

Description: 6-Mercaptopurine Riboside is a substrate for adenosine deaminase. 6-Mercaptopurine riboside is a nucleoside analog where the purine base is 6-mercaptopurine, which is linked to a ribose sugar. 6-Mercaptopurine riboside is a valuable compound in cancer treatment and immunosuppressive therapy due to its ability to interfere with nucleic acid synthesis and purine metabolism. Its structural similarity to normal nucleosides allows it to be incorporated into RNA and DNA, disrupting the normal function and growth of cells.

CAT: BRP-01931

CAS: 574-25-4

Molecular Formula: C10H12N4O4S

Molecular Weight: 284.29

Purity: 90%

Appearance: White to Beige Solid

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Storage: Store at -20 °C, stored under nitrogen

Density: 2.02±0.1 g/cm3

Melting Point: 198-200 °C (dec.)

Boiling Point: 714.7±70.0 °C at 760 mmHg

Application: Antimetabolites, Antineoplastic

InChIKey: NKGPJODWTZCHGF-KQYNXXCUSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Very Slightly, Heated)

SMILES: C1=NC(=S)C2=C(N1)N(C=N2)C3C(C(C(O3)CO)O)O

IUPAC Name: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione

InChI: InChI=1S/C10H12N4O4S/c15-1-4-6(16)7(17)10(18-4)14-3-13-5-8(14)11-2-12-9(5)19/h2-4,6-7,10,15-17H,1H2,(H,11,12,19)/t4-,6-,7-,10-/m1/s1

Synonyms: 6-Thioinosine; Ribosyl-6-thiopurine; 6-Thio-9-β-D-ribofuranoside; 6-Mercapto-9-β-D-ribofuranosyl-9H-purine; 6-Mercaptoinosine; 6-Mercaptopurine 9-β-D-ribofuranoside; 6-Mercaptopurine ribonucleoside; 6-MPR; 6-Thiopurine ribonucleoside; 6-Thiopurine riboside; 9-β-D-Ribofuranosyl-6-mercaptopurine; 9-β-D-Ribofuranosyl-9H-purine-6-thiol; 9-β-D-Ribofuranosyl-9H-purine-6-thione; 9-β-D-Ribofuranosylpurine-6-thiol; 9-β-D-Ribofuranosylpurine-6-thione; Chembridge 5676375; NSC 4911; Thioinosine

2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine

Description: 2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a valuable nucleoside analog used in chemical synthesis, biochemical, and pharmacological research. The acetylated ribose and dichlorinated purine base allow scientists to study the effects of these modifications on nucleotide function, enzyme interactions, and potential therapeutic applications in antiviral and anticancer treatments. This compound provides insights into the role of modified nucleosides in various biological processes and the development of novel therapeutic agents.

CAT: BRP-01932

CAS: 3056-18-6

Molecular Formula: C16H16Cl2N4O7

Molecular Weight: 447.23

Purity: ≥95%

Appearance: Off-White to Pale Yellow Solid

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Storage: Store at -20 °C, sealed storage, away from moisture

Density: 1.69±0.1 g/cm3 (Predicted)

Melting Point: 151-154°C

Boiling Point: 555.3±60.0°C (Predicted)

InChIKey: PYXZXWLFAMZVPY-SDBHATRESA-N

Solubility: Soluble in Chloroform (Slightly), DMSO (Slightly)

SMILES: CC(=O)OCC1C(C(C(O1)N2C=NC3=C2N=C(N=C3Cl)Cl)OC(=O)C)OC(=O)C

IUPAC Name: [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2,6-dichloropurin-9-yl)oxolan-2-yl]methyl acetate

InChI: InChI=1S/C16H16Cl2N4O7/c1-6(23)26-4-9-11(27-7(2)24)12(28-8(3)25)15(29-9)22-5-19-10-13(17)20-16(18)21-14(10)22/h5,9,11-12,15H,4H2,1-3H3/t9-,11-,12-,15-/m1/s1

Synonyms: 9-(2,3,5-Tri-O-acetyl-beta-D-ribofuranosyl)-2,6-dichloropurine; NSC 76763; (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,6-dichloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate; 2,6-Dichloro-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-9H-purine; 2,6-Dichloro-9-(2-O,3-O,5-O-triacetyl-beta-D-ribofuranosyl)-9H-purine; 9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-2,6-dichloro-9H-purine

3',5'-Di-O-acetyl-5-bromo-2'-O-methyluridine

Description: 3',5'-Di-O-acetyl-5-bromo-2'-O-methyluridine is a remarkable biomedical compound with a resolute focus on research of notorious RNA viruses, such as hepatitis C and influenza.

CAT: BRP-01933

CAS: 1188522-81-7

Molecular Formula: C14H17BrN2O8

Molecular Weight: 421.20

Purity: ≥95%

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Storage: Store at -20 °C, sealed storage, away from moisture

Density: 1.63±0.1 g/cm3

Melting Point: 162-164 °C

InChIKey: SRIIZANGRRSQIV-PRULPYPASA-N

SMILES: CC(=O)OCC1C(C(C(O1)N2C=C(C(=O)NC2=O)Br)OC)OC(=O)C

IUPAC Name: [(2R,3R,4R,5R)-3-acetyloxy-5-(5-bromo-2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-2-yl]methyl acetate

InChI: InChI=1S/C14H17BrN2O8/c1-6(18)23-5-9-10(24-7(2)19)11(22-3)13(25-9)17-4-8(15)12(20)16-14(17)21/h4,9-11,13H,5H2,1-3H3,(H,16,20,21)/t9-,10-,11-,13-/m1/s1

Synonyms: ((2R,3R,4R,5R)-3-acetoxy-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-2-yl)methyl acetate; 5-bromo-3',5'-diacetyl-2'-O-methyluridine; Uridine, 5-bromo-2'-O-methyl-, 3',5'-diacetate; 5-Bromo-2'-O-methyluridine 3',5'-diacetate

9-((3aR,4R,6R,6aR)-2,2-Dimethyl-6-((methylamino)methyl)tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-amine

Description: 9-((3aR,4R,6R,6aR)-2,2-Dimethyl-6-((methylamino)methyl)tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-amine is a formidable and effective suppressor of adenosine kinases, utilized in the amelioration of malignancies and inflammatory disorders, in addition to assorted neurological ailments rooted in adenosine signaling. Its molecular configuration bears striking resemblance to adenosine, facilitating facile assimilation into cellular paths. This enables the thwarting of intracellular effects of adenosine, leading to beneficial outcomes.

CAT: BRP-01934

CAS: 34245-49-3

Molecular Formula: C14H20N6O3

Molecular Weight: 320.35

Purity: 97%

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Storage: Store at 2-8 °C, protect from light

Density: 1.66±0.1 g/cm3

Boiling Point: 537.5±60.0 °C at 760 mmHg

InChIKey: SJXNSGJHLDXAIO-QYVSTXNMSA-N

SMILES: CC1(OC2C(OC(C2O1)N3C=NC4=C(N=CN=C43)N)CNC)C

IUPAC Name: 9-[(3aR,4R,6R,6aR)-2,2-dimethyl-6-(methylaminomethyl)-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]purin-6-amine

InChI: InChI=1S/C14H20N6O3/c1-14(2)22-9-7(4-16-3)21-13(10(9)23-14)20-6-19-8-11(15)17-5-18-12(8)20/h5-7,9-10,13,16H,4H2,1-3H3,(H2,15,17,18)/t7-,9-,10-,13-/m1/s1

Synonyms: Adenosine, 5'-deoxy-5'-(methylamino)-2',3'-O-(1-methylethylidene)-; 5'-Deoxy-5'-(methylamino)-2',3'-O-(1-methylethylidene)adenosine; Adenosine, 5'-deoxy-2',3'-O-isopropylidene-5'-(methylamino)-

5-Chlorouridine

Description: 5-Chlorouridine is a valuable modified nucleoside used in biochemical, pharmacological, and chemical biology research. Its chlorination at the 5-position allows scientists to study the effects of halogenation on nucleotide function, RNA structure, and potential therapeutic applications. This compound provides insights into the role of modified nucleosides in various biological processes and aids in the development of novel therapeutic agents and research tools.

CAT: BRP-01935

CAS: 2880-89-9

Molecular Formula: C9H11ClN2O6

Molecular Weight: 278.65

Purity: ≥98% by HPLC