What are nucleosides used for?

Nucleosides are base molecules used as starting materials for synthesizing nucleotides and phosphoramidites.

What is the difference between nucleosides and nucleotides?

Nucleosides lack phosphate groups, while nucleotides contain one or more phosphates required for enzymatic reactions.

Are nucleosides used directly in enzymatic reactions?

Nucleosides are typically chemically modified before being used in enzymatic workflows.

Can nucleosides be chemically modified?

Yes, modified nucleosides are widely used to introduce structural or functional changes in nucleic acids.

Why is nucleoside purity important?

High purity ensures correct downstream synthesis of nucleotides and phosphoramidites with predictable performance.

Nucleosides - RNA / BOC Sciences

N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-cytidine

Description: N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-cytidine, an influential nucleoside analogue with potent antiviral properties, is extensively employed across the biomedical sector. Its remarkable efficacy extends to a diverse range of DNA and RNA viruses, encompassing herpesvirus, papillomavirus, and retroviruses. Notably, this compound showcases promising outcomes in impeding viral replication, thereby presenting itself as a promising therapeutic avenue for combating viral infections and associated ailments.

CAT: BRP-01764

CAS: 251647-49-1

Molecular Formula: C40H41N3O9

Molecular Weight: 707.77

Purity: ≥95%

Appearance: White to Off-white Powder or Crystals

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at -20°C

Density: 1.26±0.1 g/cm3 (Predicted)

InChIKey: PRAZQDMVAGLVKR-XHOUGWTJSA-N

CanonicalSMILES: COCCOC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C40H41N3O9/c1-47-24-25-50-36-35(44)33(52-38(36)43-23-22-34(42-39(43)46)41-37(45)27-10-6-4-7-11-27)26-51-40(28-12-8-5-9-13-28,29-14-18-31(48-2)19-15-29)30-16-20-32(49-3)21-17-30/h4-23,33,35-36,38,44H,24-26H2,1-3H3,(H,41,42,45,46)/t33-,35-,36-,38-/m1/s1

Synonyms: 5'-O-DMT-N4-BZ-2'-O-(2-Methoxyethyl)-Cytidine; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)cytidine; N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-(2-methoxyethyl)cytidine; 5'-O-DMT-2'-O-MOE-C(Bz)

Arabinofuranosyl-hypoxanthine (ara-HX)

Description: Arabinofuranosyl-hypoxanthine is a prodrug of Vidarabine for improving the oral bioavailability, which is an antiviral drug. It is an antimetabolic nucleoside that inhibits Streptococcus pyogenes and other bacteria, as well as zirconium oxide, pulmonary vasodilation, squamous cell carcinoma, and rate constant.

CAT: BRP-01769

CAS: 7013-16-3

Molecular Formula: C10H12N4O5

Molecular Weight: 268.22

Purity: ≥98%

Appearance: White or off-white solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at 2-8 °C

Density: 2.08±0.1 g/cm3

Melting Point: 259-260 °C

Boiling Point: 797.9±60.0 °C at 760 mmHg

Application: Antiviral Agents

InChIKey: UGQMRVRMYYASKQ-UHTZMRCNSA-N

Solubility: Soluble in DMSO (Slightly), Water (Slightly)

CanonicalSMILES: C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)CO)O)O

IUPAC Name: 9-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6-,7+,10-/m1/s1

Synonyms: Arabinofuranosyl-hypoxanthine; Arabino inosine; 9-β-D-Arabinofuranosyl-1,9-dihydro-6H-purin-6-one; Hypoxanthine, 9-β-D-arabinofuranosyl-; 9-β-D-Arabinofuranosylhypoxanthine; Ara-H; Arabinosylhypoxanthine; Arainosine; Hypoxanthine arabinoside; NSC 405122; 9-(β-D-Arabinofuranosyl)-hypoxanthine

2-Amino-9-(2-O-methyl-β-D-ribofuranosyl)purine

Description: 2-Amino-9-(2-O-methyl-β-D-ribofuranosyl)purine is a renowned pharmaceutical compound, boasting its exceptional potency as an antiviral agent. With a distinctive focus on combating the likes of hepatitis C and diverse DNA viruses, this product manifests remarkable efficacy in hindering viral replication.

CAT: BRP-01770

CAS: 274259-35-7

Molecular Formula: C11H15N5O4

Molecular Weight: 281.27

Purity: ≥97%

Appearance: White or off-white solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at 2-8 °C

Density: 1.84±0.1 g/cm3

Boiling Point: 654.1±65.0 °C at 760 mmHg

InChIKey: UQKXGJSZRSHLBF-FDDDBJFASA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=CN=C(N=C32)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(2-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol

InChI: InChI=1S/C11H15N5O4/c1-19-8-7(18)6(3-17)20-10(8)16-4-14-5-2-13-11(12)15-9(5)16/h2,4,6-8,10,17-18H,3H2,1H3,(H2,12,13,15)/t6-,7-,8-,10-/m1/s1

Synonyms: 2-Amino-9-(2'-O-methyl-beta-D-ribofuranosyl)-9H-purine; 9-(2-O-Methyl-β-D-ribofuranosyl)-9H-purin-2-amine; 2-Amino-9-(2-o-methyl-β-d-ribofuranosyl)purine

2-Thiocytidine

Description: 2-Thiocytidine, a nucleoside analogue, is a potent anti-cancer agent that shows promise in treating several types of cancer, including leukemia, lymphoma, and solid tumors. Through interference with the DNA synthesis process, it effectively halts cancer cell growth, while also demonstrating antiviral activity towards HIV and hepatitis B. From these qualities, it is clear that 2-Thiocytidine holds tremendous potential as a therapeutic agent for the treatment of cancer and viral infections.

CAT: BRP-01771

CAS: 13239-97-9

Molecular Formula: C9H13N3O4S

Molecular Weight: 259.28

Purity: ≥95%

Appearance: Off-white to Dark Brown Solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at -20°C under inert atmosphere

Density: 1.85±0.1 g/cm3(Predicted)

Melting Point: 208-209 °C

Boiling Point: 540.5±60.0 °C at 760 mmHg

Symbol: s²C

InChIKey: RHFUOMFWUGWKKO-XVFCMESISA-N

Solubility: Soluble in Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=CN(C(=S)N=C1N)C2C(C(C(O2)CO)O)O

IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2-thione

InChI: InChI=1S/C9H13N3O4S/c10-5-1-2-12(9(17)11-5)8-7(15)6(14)4(3-13)16-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,17)/t4-,6-,7-,8-/m1/s1

Synonyms: Cytidine, 2-thio-; 4-amino-1-beta-D-ribofuranosylpyrimidine-2(1H)-thione; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2(1H)-thione; 2(1H)-Pyrimidinethione, 4-amino-1-β-D-ribofuranosyl-

N4-Aminocytidine

Description: N4-Aminocytidine is a cytidine analog where an amino group is attached to the nitrogen at the 4th position of the cytosine base. This modification can be used in biochemical and molecular biology research to study nucleic acid interactions, enzymatic activity, and as a potential antiviral or anticancer agent. The presence of the additional amino group can influence base pairing and the overall stability of nucleic acids, providing a useful tool for exploring nucleic acid structure and function. It inhibits the growth of Escherichia coli and Salmonella typhimurium in vitro. It binds to the bacterial ribosome and inhibits protein synthesis, which results in cell death.

CAT: BRP-01773

CAS: 57294-74-3

Molecular Formula: C9H14N4O5

Molecular Weight: 258.23

Purity: ≥98%

Appearance: White or off-white solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at 2-8 °C

Density: 1.93±0.1 g/cm3

InChIKey: RSSRMDMJEZIUJX-XVFCMESISA-N

Solubility: Soluble in DMSO (Slightly), Water (Slightly)

CanonicalSMILES: C1=CN(C(=O)N=C1NN)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydrazinylpyrimidin-2-one

InChI: InChI=1S/C9H14N4O5/c10-12-5-1-2-13(9(17)11-5)8-7(16)6(15)4(3-14)18-8/h1-2,4,6-8,14-16H,3,10H2,(H,11,12,17)/t4-,6-,7-,8-/m1/s1

Synonyms: Uridine, 4-hydrazone; Uridine 4-hydrazone; Cytidine, N-amino-; EIDD 1910; N-Aminocytidine; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydrazinylpyrimidin-2(1H)-one

5-Bromocytidine

Description: 5-Bromocytidine, an indispensable biomedicine compound, holds immense promise for combating viral infections and cancer. Functioning as a nucleoside analog, it effectively impedes the replication of viral RNA and DNA. Moreover, its integration into cellular nucleic acids and subsequent interference with their synthesis inflict cytotoxicity upon cancer cells.

CAT: BRP-01774

CAS: 3066-86-2

Molecular Formula: C9H12BrN3O5

Molecular Weight: 322.11

Purity: ≥95%

Appearance: White to Off-white Crystalline Powder

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at 2-8°C

Density: 2.28±0.1 g/cm3 (Predicted)

Melting Point: 183-185°C

Boiling Point: 555.4±60.0°C (Predicted)

InChIKey: HRDXGYQCVPZEJE-UAKXSSHOSA-N

CanonicalSMILES: C1=C(C(=NC(=O)N1C2C(C(C(O2)CO)O)O)N)Br

IUPAC Name: 4-amino-5-bromo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C9H12BrN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1

Synonyms: 5-Bromo-ribo Cytidine; 4-amino-5-bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 5-Bromo-D-cytidine

N2,N2-Dimethylguanosine

Description: N2,N2-Dimethylguanosine is a modified nucleoside where two methyl groups are attached to the nitrogen at the second position of the guanine base. This modification can affect hydrogen bonding and base pairing within nucleic acids. It is often found in tRNA and other RNA molecules, contributing to their stability and function. In biochemical research, N2,N2-dimethylguanosine is used to study enzyme interactions and the impact of methylation on nucleic acid structure and function.

CAT: BRP-01775

CAS: 2140-67-2

Molecular Formula: C12H17N5O5

Molecular Weight: 311.29

Purity: ≥95%

Appearance: White to Pale Beige Solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at -20°C

Density: 1.83±0.1 g/cm3 (Predicted)

Melting Point: >218°C (dec.)

Boiling Point: 683.6°C at 760 mmHg

Symbol: m²₂G

InChIKey: RSPURTUNRHNVGF-IOSLPCCCSA-N

Solubility: Soluble in DMSO (Slightly, Heated), Methanol (Slightly, Heated)

CanonicalSMILES: CN(C)C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-(dimethylamino)-1H-purin-6-one

InChI: InChI=1S/C12H17N5O5/c1-16(2)12-14-9-6(10(21)15-12)13-4-17(9)11-8(20)7(19)5(3-18)22-11/h4-5,7-8,11,18-20H,3H2,1-2H3,(H,14,15,21)/t5-,7-,8-,11-/m1/s1

Synonyms: N,N-Dimethylguanosine; N2-Dimethylguanosine; 2,2-Dimethylguanosine; 2-Dimethylamino-6-oxypurine riboside; 2-Dimethylguanosine; 2-(dimethylamino)-9-(beta-D-ribofuranosyl)-1,9-dihydro-6H-purin-6-one; 9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-(dimethylamino)-1H-purin-6(9H)-one

2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]inosine

Description: 2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]inosine is a remarkable and transformative compound research and development, manifesting its remarkable potential in research of an array of incessant and pernicious viral infections. As a meticulously tailored nucleoside analog, this compound exerts its magnificent influence by diligently thwarting the relentless propagation of notorious entities such as herpes simplex virus (HSV) and human immunodeficiency virus (HIV).

CAT: BRP-01778

CAS: 171284-49-4

Molecular Formula: C18H18FN5O7

Molecular Weight: 435.36

Purity: ≥95%

Appearance: White or off-white solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at 2-8 °C

Density: 1.76±0.1 g/cm3

Boiling Point: 811.6±75.0 °C at 760 mmHg

InChIKey: XUQAGOPCIUTOKD-LSCFUAHRSA-N

CanonicalSMILES: C1=CC(=CC=C1CCOC2=NC(=NC3=C2N=CN3C4C(C(C(O4)CO)O)O)F)[N+](=O)[O-]

IUPAC Name: (2R,3R,4S,5R)-2-[2-fluoro-6-[2-(4-nitrophenyl)ethoxy]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C18H18FN5O7/c19-18-21-15-12(20-8-23(15)17-14(27)13(26)11(7-25)31-17)16(22-18)30-6-5-9-1-3-10(4-2-9)24(28)29/h1-4,8,11,13-14,17,25-27H,5-7H2/t11-,13-,14-,17-/m1/s1

Synonyms: 2-Fluoro-O6-(p-nitrophenylethyl)-9-b-D-ribofuranosyl)purine; 2-Fluoro-9-(beta-D-ribofuranosyl)-6-[2-(4-nitrophenyl)ethoxy]-9H-purine; (2R,3R,4S,5R)-2-{2-Fluoro-6-[2-(4-nitro-phenyl)-ethoxy]-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol; 2-fluoro-O6-[2-(4-nitrophenyl)ethyl]inosine

8-Azaguanosine

Description: 8-Azaguanosine is a modified nucleoside where a nitrogen atom replaces the carbon at the eighth position of the guanine base. This alteration can impact base pairing and hydrogen bonding properties. It is used in biochemical and molecular biology research to study nucleic acid interactions, enzyme activity, and the structural effects of nucleobase modifications. Additionally, 8-azaguanosine is investigated for its potential antiviral and anticancer properties due to its ability to interfere with nucleic acid metabolism.

CAT: BRP-01779

CAS: 2133-80-4

Molecular Formula: C9H12N6O5

Molecular Weight: 284.23

Purity: ≥95%

Appearance: Pale yellow solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at 2-8 °C

Density: 2.49±0.1 g/cm3 (Predicted)

Melting Point: 250-252°C (dec.)

Boiling Point: 567.3°C at 760 mmHg

InChIKey: QOVIBFFZCVPCEI-UMMCILCDSA-N

Solubility: Soluble in Water

CanonicalSMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=N2)O)O)O

IUPAC Name: 5-amino-3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6H-triazolo[4,5-d]pyrimidin-7-one

InChI: InChI=1S/C9H12N6O5/c10-9-11-6-3(7(19)12-9)13-14-15(6)8-5(18)4(17)2(1-16)20-8/h2,4-5,8,16-18H,1H2,(H3,10,11,12,19)/t2-,4-,5-,8-/m1/s1

Synonyms: Azaguanosine; NSC 46788; NSC 130283; 5-Amino-3,6-dihydro-3-β-D-ribofuranosyl-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one; 3H-v-Triazolo[4,5-d]pyrimidin-7(6H)-one, 5-amino-3-β-D-ribofuranosyl-; 3H-v-Triazolo[4,5-d]pyrimidin-7-ol, 5-amino-3-β-D-ribofuranosyl-; 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,4-dihydro-3-β-D-ribofuranosyl-; 7H-v-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,6-dihydro-3-β-D-ribofuranosyl-

2-Amino-6-chloropurine-9-(2'-O-propargyl)riboside

Description: 2-Amino-6-chloropurine-9-(2'-O-propargyl)riboside, a revolutionary biomedicine, has been developed to combat various types of malignant tumors. This potent compound, an incredibly effective CDK9 inhibitory agent, promises to be a boon in the scientific community as it is capable of arresting malignant cell division and growth. Studies have shown that this complex could potentially mitigate the adverse effects of leukemia, lymphoma, and breast cancer, making it a versatile cure for widespread ailments. Furthermore, in addition to its medicinal properties, its potential application as a research tool in understanding CDK9 mediated phenomenon in cellular processes is also noteworthy.

CAT: BRP-01781

CAS: 2095417-35-7

Molecular Formula: C13H14ClN5O4

Molecular Weight: 339.73

Purity: ≥95%

Appearance: White to off-white solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at 2-8 °C

Density: 1.75±0.1 g/cm3

Boiling Point: 704.4±70.0 °C at 760 mmHg

InChIKey: QAXQMTXPZDSDLF-WOUKDFQISA-N

CanonicalSMILES: C#CCOC1C(C(OC1N2C=NC3=C2N=C(N=C3Cl)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)-4-prop-2-ynoxyoxolan-3-ol

InChI: InChI=1S/C13H14ClN5O4/c1-2-3-22-9-8(21)6(4-20)23-12(9)19-5-16-7-10(14)17-13(15)18-11(7)19/h1,5-6,8-9,12,20-21H,3-4H2,(H2,15,17,18)/t6-,8-,9-,12-/m1/s1

Synonyms: 2-Amino-6-chloro-9-(2-O-propargyl-b-D-ribofuranosyl)-9H-purine; 2-Amino-6-chloro-2'-O-propargylpurine-9-riboside; 2-Amino-6-chloro-9-(2'-O-propargyl-b-D-ribofuranosyl)purine; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-ol

6-Azauridine

Description: 6-Azauridine is a nucleoside analog where a nitrogen atom replaces the carbon at the sixth position of the uridine base, altering its chemical properties and inhibiting RNA and DNA synthesis. It is studied for its antiviral and anticancer potential due to its ability to interfere with nucleic acid metabolism. Additionally, 6-azauridine is used in biochemical research to explore the effects of nucleoside analogs on cellular processes and enzyme activities related to nucleic acid synthesis.

CAT: BRP-01782

CAS: 54-25-1

Molecular Formula: C8H11N3O6

Molecular Weight: 245.19

Purity: ≥95%

Appearance: White to Off-white Solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at 2-8°C under inert atmosphere

Density: 2.08±0.1 g/cm3

Melting Point: >238°C (dec.)

InChIKey: WYXSYVWAUAUWLD-SHUUEZRQSA-N

Solubility: Soluble in DMSO (Slightly, Heated), Methanol (Slightly, Heated), Pyridine (Slightly), Water

CanonicalSMILES: C1=NN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazine-3,5-dione

InChI: InChI=1S/C8H11N3O6/c12-2-3-5(14)6(15)7(17-3)11-8(16)10-4(13)1-9-11/h1,3,5-7,12,14-15H,2H2,(H,10,13,16)/t3-,5-,6-,7-/m1/s1

Synonyms: 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione; 2-β-D-Ribofuranosyl-as-triazine-3,5(2H,4H)-dione; 6-AzUr; 6-Azauracil 1-riboside; 6-Azauracil-β-D-riboside; NSC 32074; Ribo-azuracil; Riboazauracil; Azauridine

9-(b-D-Xylofuranosyl)adenine

Description: 9-(b-D-Xylofuranosyl)adenine is an anticancer agent. 9-(β-D-Xylofuranosyl)adenine is a nucleoside analog in which the ribose sugar of adenosine is replaced with β-D-xylofuranose, altering its interaction with nucleic acid-related enzymes. It is used in biochemical research to study the effects of sugar modifications on nucleoside function and enzyme activity. Additionally, it has potential applications in antiviral and anticancer research due to its ability to disrupt nucleic acid synthesis and function.

CAT: BRP-01784

CAS: 524-69-6

Molecular Formula: C10H13N5O4

Molecular Weight: 267.24

Purity: ≥95%

Appearance: White solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at 2-8 °C

Density: 2.08±0.1 g/cm3 (Predicted)

Melting Point: 125-140°C

Boiling Point: 676.3±65.0°C (Predicted)

InChIKey: OIRDTQYFTABQOQ-GAWUUDPSSA-N

Solubility: Soluble in DMF, DMSO, Methanol, Water

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N

IUPAC Name: (2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6+,7-,10-/m1/s1

Synonyms: Xylo-adenosine; NSC7359; 9-β-D-Xylofuranosyladenine; NSC 7359; (2R,3R,4R,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Adenine xyloside; Xylosyladenine; Xylosyl A; 9-β-D-Xylofuranosyl-9H-purin-6-amine; Adenine, 9-β-D-xylofuranosyl-; Adenine β-D-xylofuranoside; Adenine-9-β-D-xylofuranoside; AMG 002370; NQZ-007; NSC 7359; Xyloadenosine

5-Aminouridine

Description: 5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. It therefore exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses.

CAT: BRP-01785

CAS: 2149-76-0

Molecular Formula: C9H13N3O6

Molecular Weight: 259.22

Purity: ≥95%

Appearance: Off-white to Yellow Powder

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at -20°C

Density: 1.712±0.06 g/cm3 (Predicted)

Melting Point: 214-216°C

InChIKey: YBTWWWIJBCCYNR-UAKXSSHOSA-N

Solubility: Soluble in Methanol (Slightly, Heated), Water (Slightly, Sonicated)

CanonicalSMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)N

IUPAC Name: 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H13N3O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2,10H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1

Synonyms: 5-Amino Uridine; 5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5-Amino-1-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione; NSC 72560

Related CAS: 116154-74-6 (monohydrochloride)

Kinetin Riboside

Description: Kinetin Riboside is a cell growth inhibitor used as an anticancer and antiviral agent. Kinetin Riboside is a modified nucleoside where a furfuryl group is attached to the sixth position nitrogen of the adenosine base. This modification is utilized in biochemical research to investigate nucleic acid structure and function, RNA modification studies, and drug development due to its potential to modulate nucleic acid metabolism. Its altered chemical properties make it a valuable tool for understanding RNA biology and exploring therapeutic applications.

CAT: BRP-01786

CAS: 4338-47-0

Molecular Formula: C15H17N5O5

Molecular Weight: 347.33

Purity: 98%

Appearance: White to Pale Brown Solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: 2-8 °C

Density: 1.78±0.1 g/cm3

Melting Point: >129°C (dec.)

Boiling Point: 683.7±65.0°C at 760 mmHg

InChIKey: CAGLGYNQQSIUGX-SDBHATRESA-N

Solubility: Soluble in DMSO (Slightly), Ethanol (Slightly, Heated, Sonicated), Methanol (Very Slightly)

CanonicalSMILES: C1=COC(=C1)CNC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O

IUPAC Name: (2R,3R,4S,5R)-2-[6-(furan-2-ylmethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C15H17N5O5/c21-5-9-11(22)12(23)15(25-9)20-7-19-10-13(17-6-18-14(10)20)16-4-8-2-1-3-24-8/h1-3,6-7,9,11-12,15,21-23H,4-5H2,(H,16,17,18)/t9-,11-,12-,15-/m1/s1

Synonyms: Furfurylaminopurineriboside; N6-Furfuryladenosine; 6-Furfurylaminopurine Riboside, N-(2-Furanylmethyl)adenosine; NSC 120958; Ribosylkinetin; Kinetin-9-riboside; N6-(2-Furanyl-methyl)adenosine; N-(2-Furylmethyl)-9-pentofuranosyl-9H-purin-6-amine

3-Deazauridine

Description: 3-Deazauridine is a nucleoside analog. It is converted intracellularly to 3-deazauridine triphosphate, which competitively inhibits cytidine triphosphate synthetase thereby inhibiting biosynthesis of the nucleic acid cytidine 5'-triphosphate (CTP).

CAT: BRP-01787

CAS: 23205-42-7

Molecular Formula: C10H13NO6

Molecular Weight: 243.21

Purity: ≥95%

Appearance: White to Pale Beige Solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at 2-8°C

Density: 1.718±0.06 g/cm3 (Predicted)

Melting Point: 230-232 °C

Boiling Point: 569.2±50.0°C (Predicted)

Application: Antimetabolites, Antineoplastic

InChIKey: CBOKZNLSFMZJJA-PEBGCTIMSA-N

Solubility: Soluble in DMF (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=CN(C(=O)C=C1O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxypyridin-2-one

InChI: InChI=1S/C10H13NO6/c12-4-6-8(15)9(16)10(17-6)11-2-1-5(13)3-7(11)14/h1-3,6,8-10,12-13,15-16H,4H2/t6-,8-,9-,10-/m1/s1

Synonyms: 4-Hydroxy-1-beta-D-ribofuranosyl-2(1H)-pyridinone; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxypyridin-2(1H)-one; 1-β-D-Ribofuranosyl-4-hydroxy-2-pyridone; 4-Hydroxy-1-(β-D-ribofuranosyl)-2-pyridone; NSC 126849

(R)-N-(2,3-dihydro-1H-indenyl)adenosine

Description: PD-117519 is a N6-substituted adenosine receptor agonist. It shows oral antihypertensive activity in pharmacological animal models. It is used as a potential antihypertensive agent.

CAT: BRP-01789

CAS: 96392-15-3

Molecular Formula: C19H21N5O4

Molecular Weight: 383.40

Purity: ≥95%

Appearance: White solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at -20°C

Density: 1.71±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr

Melting Point: 185-187 °C

Boiling Point: 723.3±70.0 °C | Condition: Press: 760 Torr

Application: PD-117519 is used as a potential antihypertensive agent.

Shelf Life: 2 month in rt, long time

InChIKey: FSKMJUWPFLDDRS-BYMDKACISA-N

Solubility: Soluble in DMSO (>3.9 mg/mL)

CanonicalSMILES: C1CC2=CC=CC=C2C1NC3=NC=NC4=C3N=CN4C5C(C(C(O5)CO)O)O

IUPAC Name: (2R,3R,4S,5R)-2-[6-[[(1R)-2,3-dihydro-1H-inden-1-yl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C19H21N5O4/c25-7-13-15(26)16(27)19(28-13)24-9-22-14-17(20-8-21-18(14)24)23-12-6-5-10-3-1-2-4-11(10)12/h1-4,8-9,12-13,15-16,19,25-27H,5-7H2,(H,20,21,23)/t12-,13-,15-,16-,19-/m1/s1

Synonyms: N-[(R)-Indan-1-yl]adenosine; PD 117519; PD117519; PD-117519; N-[(1R)-2,3-Dihydro-1H-inden-1-yl]adenosine; N-[[(R)-2,3-Dihydro-1H-inden]-1α-yl]adenosine; (2R,3R,4S,5R)-2-(6-(((R)-2,3-dihydro-1H-inden-1-yl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; CI-947; CI 947; CI 947

1-Methylinosine

Description: 1-Methylinosine is a modified nucleoside which is present in higher concentrations in the urinary excretion of patients afflicted with breast cancer. It acts as a biomarker for diagnosis of the disease.

CAT: BRP-01790

CAS: 2140-73-0

Molecular Formula: C11H14N4O5

Molecular Weight: 282.26

Purity: ≥95%

Appearance: White Solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at -20°C

Density: 1.88±0.1 g/cm3 (Predicted)

Melting Point: 211-212 °C

Boiling Point: 695.3±65.0 °C at 760 mmHg

Symbol: m¹I

InChIKey: WJNGQIYEQLPJMN-IOSLPCCCSA-N

Solubility: Soluble in Chloroform (Slightly, Heated), DMSO (Slightly, Heated)

CanonicalSMILES: CN1C=NC2=C(C1=O)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpurin-6-one

InChI: InChI=1S/C11H14N4O5/c1-14-3-13-9-6(10(14)19)12-4-15(9)11-8(18)7(17)5(2-16)20-11/h3-5,7-8,11,16-18H,2H2,1H3/t5-,7-,8-,11-/m1/s1

Synonyms: N1-Methylinosine; 1-Methyl-Inosine; Inosine, 1-methyl-; 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1-methyl-1,9-dihydro-6H-purin-6-one

2'-O-(2-Methoxyethyl)-2-aminoadenosine

Description: 2'-O-(2-Methoxyethyl)-2-aminoadenosine is a vital compound widely used in the biomedical industry. It exhibits potent antiviral properties, making it a valuable tool in the treatment and research of viral infections such as HIV.

CAT: BRP-01793

CAS: 256224-13-2

Molecular Formula: C13H20N6O5

Molecular Weight: 340.34

Purity: ≥95%

Appearance: White to off-white solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at 2-8 °C

Density: 1.81±0.1 g/cm3

Boiling Point: 734.5±70.0°C at 760 mmHg

InChIKey: ZPWSGIIALWUBNX-WOUKDFQISA-N

CanonicalSMILES: COCCOC1C(C(OC1N2C=NC3=C(N=C(N=C32)N)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(2,6-diaminopurin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)oxolan-3-ol

InChI: InChI=1S/C13H20N6O5/c1-22-2-3-23-9-8(21)6(4-20)24-12(9)19-5-16-7-10(14)17-13(15)18-11(7)19/h5-6,8-9,12,20-21H,2-4H2,1H3,(H4,14,15,17,18)/t6-,8-,9-,12-/m1/s1

Synonyms: Adenosine, 2-amino-2'-O-(2-methoxyethyl)-; 2-Amino-2'-O-(2-methoxyethyl)adenosine; (2R,3R,4R,5R)-5-(2,6-Diamino-9H-purin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol; 9-[2-O-(2-Methoxyethyl)-β-D-xylofuranosyl]-9H-purine-2,6-diamine

1-Methylguanosine

Description: 1-Methylguanosine is a methylated nucleoside. It is known that some modified, especially methylated, nucleosides originating from RNA degradation are excreted in abnormal levels in the urine of patients with malignant tumours. These nucleosides have been proposed as tumour markers. Their measurement could provide a non-invasive diagnostic method, help identify different cancers, and monitor any therapeutic effects.

CAT: BRP-01794

CAS: 2140-65-0

Molecular Formula: C11H15N5O5

Molecular Weight: 297.27

Purity: ≥95%

Appearance: White to Off-white Solid

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at -20°C under inert atmosphere

Density: 2.02±0.1 g/cm3 (Predicted)

Melting Point: 163 °C

Boiling Point: 737.4±70.0 °C at 760 mmHg

Symbol: m¹G

InChIKey: UTAIYTHAJQNQDW-KQYNXXCUSA-N

Solubility: Soluble in Methanol (Slightly), Water (Slightly)

CanonicalSMILES: CN1C(=O)C2=C(N=C1N)N(C=N2)C3C(C(C(O3)CO)O)O

IUPAC Name: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpurin-6-one

InChI: InChI=1S/C11H15N5O5/c1-15-9(20)5-8(14-11(15)12)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14)/t4-,6-,7-,10-/m1/s1

Synonyms: N1-Methylguanosine; Guanosine, 1-methyl-; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1-methyl-1H-purin-6(9H)-one; 1-Methyl-2-amino-9-(β-D-ribofuranosyl)-9H-purine-6(1H)-one; NSC 70897

8-Chloroadenosine

Description: 8-Chloroadenosine is an analog of adenosine. It is metabolized in vivo to 8-Chloro-ATP. It depletes ATP and inhibits tumor growth in hematological malignancies. It also inhibits tumor growth in lung and breast cancer cell lines. It incorporates into RNA during transcription and inhibits RNA synthesis. It mitotics catastrophe and induces G2/M cell cycle arrest in A549 and H1299 cells.
It is a useful research chemical and has cytotoxicity effects.

CAT: BRP-01796

CAS: 34408-14-5

Molecular Formula: C10H12ClN5O4

Molecular Weight: 301.69

Purity: ≥98% by HPLC

Appearance: White to Off-white Crystalline Powder

Size	Price	Stock	Quantity
--	--	--

Inquiry

Storage: Store at -20°C

Density: 2.19±0.1 g/cm3

Melting Point: 189-191 °C

Boiling Point: 707.4±70.0°C at 760 mmHg

InChIKey: MHDPPLULTMGBSI-UUOKFMHZSA-N

Solubility: Soluble in DMSO, Water

CanonicalSMILES: C1=NC(=C2C(=N1)N(C(=N2)Cl)C3C(C(C(O3)CO)O)O)N

IUPAC Name: (2R,3R,4S,5R)-2-(6-amino-8-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H12ClN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)/t3-,5-,6-,9-/m1/s1

Synonyms: 6-Amino-8-chloropurine riboside; 8-Cl-Ado; 8-Chloro-adenosine; (2R,3R,4S,5R)-2-(6-amino-8-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Chloro-D-adenosine