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3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)cytidine

Description: 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)cytidine, a nucleoside analogue drug, acts as an inhibitor of viral replication to alleviate hepatitis B and C. With its action aimed at blocking reverse transcriptase, the virus loses its ability to propagate. Besides being effective against these chronic infections, the drug has exhibited encouraging results in combatting cancerous cells and HIV.
CAT: BRP-01678
CAS: 69304-42-3
Molecular Formula: C21H39N3O6Si2
Molecular Weight: 485.72
Purity: ≥95% by HPLC
Appearance: White to off-white crystalline powder
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Density: 1.24±0.1 g/cm3
Melting Point: 248-250 °C
Boiling Point: 517.7±60.0 °C at 760 mmHg
InChIKey: KPNSXQNKDQMBAW-VBSBHUPXSA-N
CanonicalSMILES: CC(C)[Si]1(OCC2C(C(C(O2)N3C=CC(=NC3=O)N)O)O[Si](O1)(C(C)C)C(C)C)C(C)C
IUPAC Name: 1-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-4-aminopyrimidin-2-one
InChI: InChI=1S/C21H39N3O6Si2/c1-12(2)31(13(3)4)27-11-16-19(29-32(30-31,14(5)6)15(7)8)18(25)20(28-16)24-10-9-17(22)23-21(24)26/h9-10,12-16,18-20,25H,11H2,1-8H3,(H2,22,23,26)/t16-,18-,19-,20-/m1/s1
Synonyms: 3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-cytidine; 3',5'-TIPDS-Cr; 3',5'-TIPS-cytidine; 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)-D-cytidine; 3',5'-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl]cytidine

Fludarabine

Description: Arabinofuranosyl-2-fluoro-adenin is an adenosine deaminase resistant analog of 9-β-D-arabinofuranosyladenine (ara-A) that inhibits DNA synthesis. It is commonly used as an antitumor agent for its antiproliferative property.
CAT: BRP-01682
CAS: 21679-14-1
Molecular Formula: C10H12FN5O4
Molecular Weight: 285.23
Purity: ≥95%
Appearance: White to Off-white Crystals
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Storage: Store at 2-8°C
Density: 2.17±0.1 g/cm3 (Predicted)
Melting Point: >256°C (dec.)
Boiling Point: 747.3±70.0°C (Predicted)
Flash Point: 405.8°C
Application: Antineoplastic Agents
InChIKey: HBUBKKRHXORPQB-FJFJXFQQSA-N
Solubility: Soluble in DMF, DMSO, Methanol, Ethanol, Water (Sparingly)
CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(N=C2N)F
IUPAC Name: (2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChI: InChI=1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/m1/s1
Synonyms: 2-F-Ara-Ar; 2-Fluoro-arabinoadenosine; 9-(β-D-Arabinofuranosyl)-2-fluoroadenine; F-ara-A; NSC 118218; (2R,3S,4S,5R)-2-(6-Amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2-fluoro-9-β-D-arabinofuranosyladenine
Related CAS: 75607-67-9 ; (phosphate)

2'-O-Allyladenosine

Description: 2'-O-Allyladenosine is a compound of great significance in the realm of biomedical science and industry, finding profound applications in the domain of antiviral therapeutics, particularly in studying the pernicious RNA viruses.
CAT: BRP-01693
CAS: 133766-26-4
Molecular Formula: C13H17N5O4
Molecular Weight: 307.31
Purity: 98%
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Density: 1.66±0.1 g/cm3
Boiling Point: 632.8±65.0 °C at 760 mmHg
InChIKey: DUQRPQVBZQQZPL-QYVSTXNMSA-N
CanonicalSMILES: C=CCOC1C(C(OC1N2C=NC3=C(N=CN=C32)N)CO)O
IUPAC Name: (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-(hydroxymethyl)-4-prop-2-enoxyoxolan-3-ol
InChI: InChI=1S/C13H17N5O4/c1-2-3-21-10-9(20)7(4-19)22-13(10)18-6-17-8-11(14)15-5-16-12(8)18/h2,5-7,9-10,13,19-20H,1,3-4H2,(H2,14,15,16)/t7-,9-,10-,13-/m1/s1
Synonyms: 2'-(O-allyl) Adenosine; 2'-O-Allyl-D-adenosine; 2'-O-2-Propenyladenosine; (2R,3R,4R,5R)-4-(allyloxy)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

2'-O-Allylguanosine

Description: 2'-O-Allylguanosine is a nucleoside derivative widely employed in the realm of biomedical research, boasting immense potential for the development of antiviral medications, inclusive of therapeutic solutions targeting HIV, hepatitis C, and sundry viral afflictions.
CAT: BRP-01694
CAS: 133766-28-6
Molecular Formula: C13H17N5O5
Molecular Weight: 323.30
Purity: 95%
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Density: 1.77±0.1 g/cm3
InChIKey: XCAPQNAAANDMJX-WOUKDFQISA-N
CanonicalSMILES: C=CCOC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O
IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-prop-2-enoxyoxolan-2-yl]-1H-purin-6-one
InChI: InChI=1S/C13H17N5O5/c1-2-3-22-9-8(20)6(4-19)23-12(9)18-5-15-7-10(18)16-13(14)17-11(7)21/h2,5-6,8-9,12,19-20H,1,3-4H2,(H3,14,16,17,21)/t6-,8-,9-,12-/m1/s1
Synonyms: 2'-(O-allyl) Guanosine; 2'-O-Allyl-D-guanosine; 9-((2R,3R,4R,5R)-3-(Allyloxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-amino-1H-purin-6(9H)-one; 2'-O-2-Propen-1-ylguanosine

2'-O-Allyluridine

Description: 2'-O-Allyluridine, a potent biomedical compound renowned for its efficacy in combating viral infections, such as hepatitis C and herpes simplex, emerges as a pivotal therapeutic agent. Its unrivaled antiviral attributes empower it to effectively impede viral replication. Notably esteemed, this compound has secured its place within numerous esteemed research databases, unveiling valuable insights into its chemical properties and synthesis methodologies, prevalently furnished by reputable chemical sources.
CAT: BRP-01695
CAS: 133766-24-2
Molecular Formula: C12H16N2O6
Molecular Weight: 284.27
Purity: 98%
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Density: 1.45±0.1 g/cm3
InChIKey: NGZRTPYYZWYZSO-QCNRFFRDSA-N
CanonicalSMILES: C=CCOC1C(C(OC1N2C=CC(=O)NC2=O)CO)O
IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-prop-2-enoxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C12H16N2O6/c1-2-5-19-10-9(17)7(6-15)20-11(10)14-4-3-8(16)13-12(14)18/h2-4,7,9-11,15,17H,1,5-6H2,(H,13,16,18)/t7-,9-,10-,11-/m1/s1
Synonyms: 2'-O-Allyl-D-uridine; 2'-(O-allyl) Uridine; 2'-O-2-Propen-1-yluridine

5-(1-Propynyl)-2'-O-methyluridine

Description: 5-(1-Propynyl)-2'-O-methyluridine is a remarkable potent antiviral compound acting as an expert inhibitor of RNA viruses, boasting an ability to curb the notorious influenza virus.
CAT: BRP-01699
CAS: 179817-95-9
Molecular Formula: C13H16N2O6
Molecular Weight: 296.28
Purity: ≥97%
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Density: 1.48±0.1 g/cm3
InChIKey: KPJZKNCZUWDUIF-DNRKLUKYSA-N
CanonicalSMILES: CC#CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)OC
IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione
InChI: InChI=1S/C13H16N2O6/c1-3-4-7-5-15(13(19)14-11(7)18)12-10(20-2)9(17)8(6-16)21-12/h5,8-10,12,16-17H,6H2,1-2H3,(H,14,18,19)/t8-,9-,10-,12-/m1/s1
Synonyms: 5-Propynyl-2'-(O-Methyl) Uridine; 1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-(prop-1-yn-1-yl)pyrimidine-2,4(1H,3H)-dione; 2'-O-Methyl-5-prop-1-yn-1-yluridine; 2'-O-Methyl-5-propynyluridine

5-(1-Propynyl)-2'-O-methylcytidine

Description: 5-(1-Propynyl)-2'-O-methylcytidine is a robust and efficacious antiviral compound, finding profound utility in the research of various virological malaises such as respiratory syncytial virus (RSV), influenza and hemorrhagic fever viruses. Its mechanism of action lies in thwarting viral replication and averting viral dissemination within the host organism.
CAT: BRP-01700
CAS: 179817-96-0
Molecular Formula: C13H17N3O5
Molecular Weight: 295.29
Purity: ≥95%
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Density: 1.47±0.1 g/cm3
Boiling Point: 522.4±60.0 °C at 760 mmHg
InChIKey: RDNYOZGTGXUIIY-DNRKLUKYSA-N
CanonicalSMILES: CC#CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)OC
IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-5-prop-1-ynylpyrimidin-2-one
InChI: InChI=1S/C13H17N3O5/c1-3-4-7-5-16(13(19)15-11(7)14)12-10(20-2)9(18)8(6-17)21-12/h5,8-10,12,17-18H,6H2,1-2H3,(H2,14,15,19)/t8-,9-,10-,12-/m1/s1
Synonyms: 5-Propynyl-2'-(O-Methyl) Cytidine; Cytidine, 2'-O-methyl-5-(1-propynyl)-; 4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-(prop-1-yn-1-yl)pyrimidin-2(1H)-one; 2'-O-Methyl-5-prop-1-yn-1-ylcytidine

3'-O-Allyladenosine

Description: 3'-O-Allyladenosine, a vital compound in the field of biomedicine, serves as a fundamental element for investigating adenosine receptors. These receptors, implicated in a multitude of ailments encompassing cardiovascular disorders, immunological responses, and neurodegenerative afflictions, hold great importance. This particular product is frequently employed to delve into the potential therapeutic applications of adenosine receptor modulation, specifically targeting conditions like ischemic heart disease, asthma, and malignancies.
CAT: BRP-01701
CAS: 400820-99-7
Molecular Formula: C13H17N5O4
Molecular Weight: 307.31
Purity: 98%
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Density: 1.66±0.1 g/cm3
Boiling Point: 632.8±65.0 °C at 760 mmHg
InChIKey: KURUYHOEDIRMCE-QYVSTXNMSA-N
CanonicalSMILES: C=CCOC1C(OC(C1O)N2C=NC3=C(N=CN=C32)N)CO
IUPAC Name: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-prop-2-enoxyoxolan-3-ol
InChI: InChI=1S/C13H17N5O4/c1-2-3-21-10-7(4-19)22-13(9(10)20)18-6-17-8-11(14)15-5-16-12(8)18/h2,5-7,9-10,13,19-20H,1,3-4H2,(H2,14,15,16)/t7-,9-,10-,13-/m1/s1
Synonyms: 3'-O-Allyl-D-adenosine; 3'-(O-allyl) Adenosine; 3'-O-allyl Adenosine; (2R,3R,4S,5R)-4-(allyloxy)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3-ol; 3'-O-2-Propen-1-yladenosine

3'-O-Allylguanosine

Description: 3'-O-Allylguanosine, a widely used biomedicine product in research, presents itself as a paramount avenue to explore the antiviral properties exhibited by guanosine derivatives. Its prominent role extends to serving as a pivotal reference compound, wherein its efficacy in combating viral infections, namely HIV, hepatitis, and respiratory viruses, can be meticulously evaluated.
CAT: BRP-01702
Molecular Formula: C13H17N5O5
Molecular Weight: 323.30
Purity: 98%
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InChIKey: XCRVSUORBIBONA-WOUKDFQISA-N
CanonicalSMILES: C=CCOC1C(OC(C1O)N2C=NC3=C2N=C(NC3=O)N)CO
IUPAC Name: 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-prop-2-enoxyoxolan-2-yl]-1H-purin-6-one
InChI: InChI=1S/C13H17N5O5/c1-2-3-22-9-6(4-19)23-12(8(9)20)18-5-15-7-10(18)16-13(14)17-11(7)21/h2,5-6,8-9,12,19-20H,1,3-4H2,(H3,14,16,17,21)/t6-,8-,9-,12-/m1/s1
Synonyms: 3'-(O-allyl) Guanosine; 3'-O-Allyl-D-guanosine; 9-((2R,3R,4S,5R)-4-(allyloxy)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-amino-1,9-dihydro-6H-purin-6-one

3'-O-Allyluridine

Description: 3'-O-Allyluridine, a vital compound extensively employed in the biomedical sector, plays a pivotal role in combating diverse ailments. Brimming with extraordinary antiviral and anticancer attributes, this remarkable entity boasts immense worth in the realm of antiviral medications and chemotherapeutic agents. With its profound ability to specifically target and impede the replication of both viruses and malignant cells, this compound unfurls a vast array of prospects for potential therapeutic interventions against viral infections and neoplastic disorders.
CAT: BRP-01703
Molecular Formula: C12H16N2O6
Molecular Weight: 284.27
Purity: 95%
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InChIKey: PVPSBJHKGXULPJ-QCNRFFRDSA-N
CanonicalSMILES: C=CCOC1C(OC(C1O)N2CCC(=O)NC2=O)CO
IUPAC Name: 1-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-prop-2-enoxyoxolan-2-yl]-1,3-diazinane-2,4-dione
InChI: InChI=1S/C12H18N2O6/c1-2-5-19-10-7(6-15)20-11(9(10)17)14-4-3-8(16)13-12(14)18/h2,7,9-11,15,17H,1,3-6H2,(H,13,16,18)/t7-,9-,10-,11-/m1/s1
Synonyms: 3'-(O-allyl) Uridine; 3'-O-Allyl-D-uridine; 1-((2R,3R,4S,5R)-4-(allyloxy)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

3'-O-Allylcytidine

Description: 3'-O-Allylcytidine, a cutting-edge biomedical innovation, stands as a pivotal resource in combating a wide range of diseases. It showcases an exquisite modification of cytidine, unveiling extraordinary potential in the selective eradication of cancerous cells and hindering their malignant proliferation. Furthermore, this compound's remarkable antiviral attributes have garnered significant attention, empowering its utilization against specific strains of viral infections.
CAT: BRP-01704
Molecular Formula: C12H17N3O5
Molecular Weight: 283.28
Purity: 98%
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InChIKey: SUDPDZLUFKFRMW-QCNRFFRDSA-N
CanonicalSMILES: C=CCOC1C(OC(C1O)N2C=CC(=NC2=O)N)CO
IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-prop-2-enoxyoxolan-2-yl]pyrimidin-2-one
InChI: InChI=1S/C12H17N3O5/c1-2-5-19-10-7(6-16)20-11(9(10)17)15-4-3-8(13)14-12(15)18/h2-4,7,9-11,16-17H,1,5-6H2,(H2,13,14,18)/t7-,9-,10-,11-/m1/s1
Synonyms: 3'-O-Allyl-D-cytidine; 3'-(O-allyl) Cytidine; 1-((2R,3R,4S,5R)-4-(allyloxy)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-aminopyrimidin-2(1H)-one

3'-O-Methylinosine

Description: 3'-O-Methylinosine is a cutting-edge compound, exhibiting tremendous promise in the research of various diseases. Its therapeutic efficacy stems from its exquisite chemical composition, meticulously designed to selectively target and combat specific drugs or diseases.
CAT: BRP-01705
CAS: 75479-64-0
Molecular Formula: C11H14N4O5
Molecular Weight: 282.25
Purity: ≥95%
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Density: 1.84±0.1 g/cm3
Boiling Point: 724.3±60.0 °C at 760 mmHg
InChIKey: ABXDBVMGRKZFRC-IOSLPCCCSA-N
CanonicalSMILES: COC1C(OC(C1O)N2C=NC3=C2N=CNC3=O)CO
IUPAC Name: 9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-1H-purin-6-one
InChI: InChI=1S/C11H14N4O5/c1-19-8-5(2-16)20-11(7(8)17)15-4-14-6-9(15)12-3-13-10(6)18/h3-5,7-8,11,16-17H,2H2,1H3,(H,12,13,18)/t5-,7-,8-,11-/m1/s1
Synonyms: 3'-(O-Methyl) Inosine; 3'-O-Methyl-D-inosine; 9-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one; 3'-OMe-I

3'-O-Methyl-5-methylcytidine

Description: 3'-O-Methyl-5-methylcytidine, a remarkable and powerful biomedicine, emerges as an indispensable weapon combating a wide spectrum of afflictions. Its paramount significance permeates the intricate orchestration of cellular dynamics and genetic predisposition. Fashioned with an unparalleled molecular framework, this extraordinary compound unveils a shimmering horizon for revolutionizing cancer therapy, battling relentless viral invasions, and addressing enigmatic autoimmune maladies.
CAT: BRP-01706
CAS: 2086327-74-2
Molecular Formula: C11H17N3O5
Molecular Weight: 271.27
Purity: ≥98%
Appearance: White to off-white powder
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Density: 1.61±0.1 g/cm3
Boiling Point: 504.6±60.0 °C at 760 mmHg
InChIKey: NQWWPNJIDJMFGO-FDDDBJFASA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)OC)O
IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-5-methylpyrimidin-2-one
InChI: InChI=1S/C11H17N3O5/c1-5-3-14(11(17)13-9(5)12)10-7(16)8(18-2)6(4-15)19-10/h3,6-8,10,15-16H,4H2,1-2H3,(H2,12,13,17)/t6-,7-,8-,10-/m1/s1
Synonyms: 3'-O-Methyl-5-methyl-D-cytidine; 3'-(O-Methyl)-5-Methyl Cytidine; 4-Amino-5-methyl-1-(3-O-methyl-β-D-xylofuranosyl)-2(1H)-pyrimidinone; 4-amino-1-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)-5-methylpyrimidin-2(1H)-one

3'-O-Propargyluridine

Description: 3'-O-Propargyluridine, an exceptional biomedical advancement, emerges as a prominent combatant against formidable viral afflictions like COVID-19. Its unparalleled antiviral capabilities lie in its profound ability to impede the replication of viral RNA. Additionally, this extraordinary compound serves as an invaluable tool for delving into the intricate realm of RNA modifications, RNA labeling, and nucleic acid-based therapeutic methodologies.
CAT: BRP-01707
CAS: 129778-59-2
Molecular Formula: C12H14N2O6
Molecular Weight: 282.25
Purity: ≥95%
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Density: 1.52±0.1 g/cm3
InChIKey: LYDAINNGFSGRDR-QCNRFFRDSA-N
CanonicalSMILES: C#CCOC1C(OC(C1O)N2C=CC(=O)NC2=O)CO
IUPAC Name: 1-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-prop-2-ynoxyoxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C12H14N2O6/c1-2-5-19-10-7(6-15)20-11(9(10)17)14-4-3-8(16)13-12(14)18/h1,3-4,7,9-11,15,17H,5-6H2,(H,13,16,18)/t7-,9-,10-,11-/m1/s1
Synonyms: 3'-O-Propargyl-D-uridine; 3'-(O-propargyl) Uridine; 3'-(O-Propargyl)uridine; 1-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 3'-O-2-propynyluridine

3'-O-Propargylcytidine

Description: 3'-O-Propargylcytidine, a powerful antiviral agent, is extensively employed to combat various viral infections induced by RNA viruses. By inhibiting viral replication and suppressing viral protein synthesis, this exceptional compound manifests remarkable efficacy against diverse viral strains. Its therapeutic potential has been demonstrated in managing RNA virus-associated disorders, encompassing respiratory tract infections, hepatitis, and influenza.
CAT: BRP-01708
CAS: 1451256-00-0
Molecular Formula: C12H15N3O5
Molecular Weight: 281.26
Purity: ≥95%
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Density: 1.51±0.1 g/cm3
Boiling Point: 544.7±60.0 °C at 760 mmHg
InChIKey: QCHWARZEPUERNY-QCNRFFRDSA-N
CanonicalSMILES: O=C1N=C(N)C=CN1C2OC(CO)C(OCC#C)C2O
IUPAC Name: 4-amino-1-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
InChI: InChI=1S/C12H15N3O5/c1-2-5-19-10-7(6-16)20-11(9(10)17)15-4-3-8(13)14-12(15)18/h1,3-4,7,9-11,16-17H,5-6H2,(H2,13,14,18)/t7-,9-,10-,11-/m1/s1
Synonyms: 3'-(O-propargyl) Cytidine; 3'-O-Propargyl-D-cytidine; 3'-O-2-Propyn-1-ylcytidine; 3'-(O-Propargyl)cytidine; 4-amino-1-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

5'-DMT-2'-(O-methyl)-guanosine (N-PAC)

Description: 5'-DMT-2'-(O-methyl)-guanosine (N-PAC) is a remarkable pharmacological compound, extensively employed in the research of select malignant neoplasms and viral afflictions. Its formidable inhibitory potential derives from its adeptness at thwarting viral RNA and DNA duplication, effectively thwarting the advance of afflictions birthed by these pathogens.
CAT: BRP-01709
CAS: 138906-94-2
Molecular Formula: C40H39N5O9
Molecular Weight: 733.77
Purity: ≥98% by HPLC
Appearance: white crystalline powder
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Density: 1.36±0.1 g/cm3
InChIKey: HVGFIPCWVIUNMP-BBKOCAQVSA-N
Solubility: Soluble in acetonitrile
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)NC(=O)COC4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-phenoxyacetamide
InChI: InChI=1S/C40H39N5O9/c1-49-28-18-14-26(15-19-28)40(25-10-6-4-7-11-25,27-16-20-29(50-2)21-17-27)53-22-31-34(47)35(51-3)38(54-31)45-24-41-33-36(45)43-39(44-37(33)48)42-32(46)23-52-30-12-8-5-9-13-30/h4-21,24,31,34-35,38,47H,22-23H2,1-3H3,(H2,42,43,44,46,48)/t31-,34-,35-,38-/m1/s1
Synonyms: 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-phenoxyacetyl)guanosine; 5'-DMT-2'-O-Me G(PAC); 5'-DMT-2'-(O-Methyl) Guanosine (n-PAC)

5'-DMT-2'-(O-methyl)-cytidine (N-PAC)

Description: 5'-DMT-2'-(O-methyl)-cytidine (N-PAC) is a formidable antiviral compound deployed in the research of viral afflictions, with an emphasized efficacy against RNA viruses. Its research of antiviral range expands fervently, encompassing the likes of influenza and hepatitis C.
CAT: BRP-01710
Molecular Formula: C39H39N3O9
Molecular Weight: 693.74
Purity: ≥98% by HPLC
Appearance: white crystalline powder
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InChIKey: PHESFPHFNNTKHW-QPCXHTPLSA-N
Solubility: Soluble in acetonitrile
IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)-2-phenoxyacetamide
InChI: InChI=1S/C39H39N3O9/c1-46-29-18-14-27(15-19-29)39(26-10-6-4-7-11-26,28-16-20-30(47-2)21-17-28)50-24-32-35(44)36(48-3)37(51-32)42-23-22-33(41-38(42)45)40-34(43)25-49-31-12-8-5-9-13-31/h4-23,32,35-37,44H,24-25H2,1-3H3,(H,40,41,43,45)/t32-,35-,36-,37-/m1/s1
Synonyms: 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-phenoxyacetyl)cytidine; 5'-DMT-2'-O-Me C(PAC)

5'-O-(Dimethoxytrityl)-5-(1-propynyl)-2'-O-methyluridine

Description: 5'-O-(Dimethoxytrityl)-5-(1-propynyl)-2'-O-methyluridine is a crucial compound used for the research and development of nucleic acid analogs. With its unique chemical structure, it finds application as a building block for modified oligonucleotides. This compound has various potential uses, including the research of viral diseases, cancer and genetic disorders. Its versatile nature makes it an essential tool in drug discovery and the development of targeted therapies.
CAT: BRP-01711
CAS: 644962-77-6
Molecular Formula: C34H34N2O8
Molecular Weight: 598.65
Purity: ≥95%
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InChIKey: LVHXICIDKOYPHH-PBAMLIMUSA-N
CanonicalSMILES: CC#CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)OC
IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione
InChI: InChI=1S/C34H34N2O8/c1-5-9-22-20-36(33(39)35-31(22)38)32-30(42-4)29(37)28(44-32)21-43-34(23-10-7-6-8-11-23,24-12-16-26(40-2)17-13-24)25-14-18-27(41-3)19-15-25/h6-8,10-20,28-30,32,37H,21H2,1-4H3,(H,35,38,39)/t28-,29-,30-,32-/m1/s1
Synonyms: 5'-DMT-5-Propynyl-2'-(O-Methyl) Uridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-5-(prop-1-yn-1-yl)pyrimidine-2,4(1H,3H)-dione; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-5-(1-propynyl)-

N4-Benzoyl-5'-O-DMT-5-methylcytidine

Description: N4-Benzoyl-5'-O-DMT-5-methylcytidine is an extensively researched biomedical compound, aiding in studying diverse ailments. Its efficacy lies in its capacity to precisely target and modulate RNA and DNA alterations, thereby impeding the growth and propagation of malignant cells.
CAT: BRP-01712
CAS: 160107-17-5
Molecular Formula: C38H37N3O8
Molecular Weight: 663.72
Purity: ≥95%
Appearance: White Crystalline Powder
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Storage: Store at RT
Density: 1.3±0.1 g/cm3
InChIKey: QCKRNDPKDFQXCO-DHKUXYTCSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)O
IUPAC Name: N-(1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide
InChI: InChI=1S/C38H37N3O8/c1-24-22-41(37(45)40-34(24)39-35(44)25-10-6-4-7-11-25)36-33(43)32(42)31(49-36)23-48-38(26-12-8-5-9-13-26,27-14-18-29(46-2)19-15-27)28-16-20-30(47-3)21-17-28/h4-22,31-33,36,42-43H,23H2,1-3H3,(H,39,40,44,45)/t31-,32-,33-,36-/m1/s1
Synonyms: 5'-DMT-5-Methyl Cytidine (n-bz); N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-5-methylcytidine; N4-Benzoyl-5'-O-dimethoxytrityl-5-methylcytidine; N-(1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide; 5'-O-(4,4'-dimethoxitrityl)-N-benzoyl-5-methylcytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-5-methylcytidine

5'-DMT-5-propynyl-uridine

Description: 5'-DMT-5-propynyl-uridine, a modified version of uridine, is a potential therapeutic agent for fighting against neurological diseases including Alzheimer's and Parkinson's. Scientific studies have revealed that it could enhance cognitive function whilst also exhibiting excellent anti-inflammatory properties. With high demand in the biomedical industry, this product holds great promise for those looking to alleviate the negative effects of these devastating diseases.
CAT: BRP-01713
CAS: 644962-76-5
Molecular Formula: C33H32N2O8
Molecular Weight: 584.62
Purity: ≥98% by HPLC
Appearance: white crystalline powder
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InChIKey: VFKJTINFVHDNPY-BUVRPPHQSA-N
Solubility: Soluble in acetonitrile
CanonicalSMILES: CC#CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O)O
IUPAC Name: 1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione
InChI: InChI=1S/C33H32N2O8/c1-4-8-21-19-35(32(39)34-30(21)38)31-29(37)28(36)27(43-31)20-42-33(22-9-6-5-7-10-22,23-11-15-25(40-2)16-12-23)24-13-17-26(41-3)18-14-24/h5-7,9-19,27-29,31,36-37H,20H2,1-3H3,(H,34,38,39)/t27-,28-,29-,31-/m1/s1
Synonyms: 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-5-prop-1-yn-1-yluridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-(1-propyn-1-yl)uridine; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-(1-propynyl)-; 5'-DMT-5-Propynyl Uridine

Frequently Asked Questions (FAQ)

What are nucleosides used for?

Nucleosides are base molecules used as starting materials for synthesizing nucleotides and phosphoramidites.

What is the difference between nucleosides and nucleotides?

Nucleosides lack phosphate groups, while nucleotides contain one or more phosphates required for enzymatic reactions.

Are nucleosides used directly in enzymatic reactions?

Nucleosides are typically chemically modified before being used in enzymatic workflows.

Can nucleosides be chemically modified?

Yes, modified nucleosides are widely used to introduce structural or functional changes in nucleic acids.

Why is nucleoside purity important?

High purity ensures correct downstream synthesis of nucleotides and phosphoramidites with predictable performance.

* Only for research. Not suitable for any diagnostic or therapeutic use.

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