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5'-DMT Cytidine (n-ibu)

Description: 5'-DMT Cytidine (N-ibu) is a specialized reagent used in the synthesis of oligonucleotides. It consists of a cytidine nucleoside modified with a 5'-DMT (dimethoxytrityl) group to protect the 5' hydroxyl position and an isobutyryl (ibu) group protecting the N4 amino group. These protective groups are essential for preventing unwanted side reactions during the stepwise assembly of nucleotide chains in automated DNA or RNA synthesis, ensuring efficient and precise production of oligonucleotides. This reagent is crucial for various applications in molecular biology, genetic research, and the development of nucleic acid-based therapeutics.
CAT: BRP-01316
CAS: 141946-76-1
Molecular Formula: C34H37N3O8
Molecular Weight: 615.67
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Density: 1.30±0.1 g/cm3
InChIKey: BSWZUOHBMILLLQ-SSKIFPDDSA-N
CanonicalSMILES: O=C1N=C(C=CN1C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(O)C2O)NC(=O)C(C)C
IUPAC Name: N-(1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)isobutyramide
InChI: InChI=1S/C34H37N3O8/c1-21(2)31(40)35-28-18-19-37(33(41)36-28)32-30(39)29(38)27(45-32)20-44-34(22-8-6-5-7-9-22,23-10-14-25(42-3)15-11-23)24-12-16-26(43-4)17-13-24/h5-19,21,27,29-30,32,38-39H,20H2,1-4H3,(H,35,36,40,41)/t27-,29-,30-,32-/m1/s1
Synonyms: N4-iBu-5'-O-DMT-cytidine; Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-

5'-DMT Guanosine (N2-Fmoc)

Description: 5'-DMT Guanosine (N2-Fmoc) is a specialized reagent used in the synthesis of oligonucleotides. It consists of a guanosine nucleoside modified with a 5'-DMT (dimethoxytrityl) group to protect the 5' hydroxyl position and an N2-Fmoc (9-fluorenylmethyloxycarbonyl) group protecting the N2 amino group. These protective groups are crucial for preventing unwanted side reactions during the stepwise assembly of nucleotide chains in automated DNA or RNA synthesis, ensuring efficient and precise production of oligonucleotides. This reagent is essential for applications in molecular biology, genetic research, and the development of nucleic acid-based therapeutics.
CAT: BRP-01317
Molecular Formula: C46H41N5O9
Molecular Weight: 807.85
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InChIKey: IFXLKLGOPCQLTM-KEJRJOSKSA-N
IUPAC Name: (9H-fluoren-9-yl)methyl (9-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)carbamate
InChI: InChI=1S/C46H41N5O9/c1-56-30-20-16-28(17-21-30)46(27-10-4-3-5-11-27,29-18-22-31(57-2)23-19-29)59-25-37-39(52)40(53)43(60-37)51-26-47-38-41(51)48-44(49-42(38)54)50-45(55)58-24-36-34-14-8-6-12-32(34)33-13-7-9-15-35(33)36/h3-23,26,36-37,39-40,43,52-53H,24-25H2,1-2H3,(H2,48,49,50,54,55)/t37-,39-,40-,43-/m1/s1
Synonyms: 5'-O-DMT-Fmoc-rG

5'-DMT Cytidine (n-PAC)

Description: 5'-DMT Cytidine (N-PAC) is a specialized reagent used in the synthesis of oligonucleotides. This compound features a cytidine nucleoside modified with a 5'-DMT (dimethoxytrityl) group to protect the 5' hydroxyl position and a PAC (phenoxyacetyl) group protecting the N4 amino group. These protective groups prevent unwanted side reactions during the stepwise assembly of nucleotide chains in automated DNA or RNA synthesis, ensuring efficient and precise production of oligonucleotides. This reagent is crucial for various applications in molecular biology, genetic research, and the development of nucleic acid-based therapeutics.
CAT: BRP-01318
Molecular Formula: C38H37N3O9
Molecular Weight: 679.72
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InChIKey: WUUDYVZMSNJZAC-MBWVZDRISA-N
IUPAC Name: N-(1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)-2-phenoxyacetamide
InChI: InChI=1S/C38H37N3O9/c1-46-28-17-13-26(14-18-28)38(25-9-5-3-6-10-25,27-15-19-29(47-2)20-16-27)49-23-31-34(43)35(44)36(50-31)41-22-21-32(40-37(41)45)39-33(42)24-48-30-11-7-4-8-12-30/h3-22,31,34-36,43-44H,23-24H2,1-2H3,(H,39,40,42,45)/t31-,34-,35-,36-/m1/s1
Synonyms: N4-Pac-5'-O-DMT-cytidine

5'-DMT Guanosine (n-PAC)

Description: 5'-DMT Guanosine (N-PAC) is a specialized reagent used in the synthesis of oligonucleotides. This compound features a guanosine nucleoside modified with a 5'-DMT (dimethoxytrityl) group to protect the 5' hydroxyl position and a PAC (phenoxyacetyl) group protecting the N2 amino group. These protective groups are essential for preventing unwanted side reactions during the stepwise assembly of nucleotide chains in automated DNA or RNA synthesis, ensuring efficient and precise production of oligonucleotides. This reagent is crucial for various applications in molecular biology, genetic research, and the development of nucleic acid-based therapeutics.
CAT: BRP-01319
CAS: 121058-81-9
Molecular Formula: C39H37N5O9
Molecular Weight: 719.74
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Density: 1.40±0.1 g/cm3
InChIKey: CGSGHXPPKFOVHX-KKKGQUFWSA-N
CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=NC6=C5N=C(NC6=O)NC(=O)COC7=CC=CC=C7)O)O
IUPAC Name: N-[9-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-phenoxyacetamide
InChI: InChI=1S/C39H37N5O9/c1-49-27-17-13-25(14-18-27)39(24-9-5-3-6-10-24,26-15-19-28(50-2)20-16-26)52-21-30-33(46)34(47)37(53-30)44-23-40-32-35(44)42-38(43-36(32)48)41-31(45)22-51-29-11-7-4-8-12-29/h3-20,23,30,33-34,37,46-47H,21-22H2,1-2H3,(H2,41,42,43,45,48)/t30-,33-,34-,37-/m1/s1
Synonyms: N2-Phenoxyacetyl-5'-O-(4,4'-dimethoxytrityl)guanosine; 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N2-phenoxyacetyl-guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-(2-phenoxyacetyl)guanosine; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(phenoxyacetyl)-; 5'-O-DMT-Pac-rG

5-(1-Propynyl)cytidine

Description: 5-(1-Propynyl)cytidine is a modified nucleoside where a propynyl group (-C≡CH) is attached to the 5-position of the cytidine base. This modification alters the chemical structure of the nucleoside, potentially affecting its base-pairing properties and interactions with other molecules. 5-(1-Propynyl)cytidine is used in various biochemical and medicinal chemistry applications, including RNA modification studies, development of nucleic acid-based therapeutics, and as a tool
CAT: BRP-01400
CAS: 188254-40-2
Molecular Formula: C12H15N3O5
Molecular Weight: 281.26
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Density: 1.59±0.1 g/cm3
Boiling Point: 550.8±60.0 °C at 760 mmHg
InChIKey: XXSIICQLPUAUDF-TURQNECASA-N
CanonicalSMILES: CC#CC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O
IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidin-2-one
InChI: InChI=1S/C12H15N3O5/c1-2-3-6-4-15(12(19)14-10(6)13)11-9(18)8(17)7(5-16)20-11/h4,7-9,11,16-18H,5H2,1H3,(H2,13,14,19)/t7-,8-,9-,11-/m1/s1
Synonyms: 5-Propynyl-ribo Cytidine; Cytidine, 5-(1-propyn-1-yl)-; 5-(1-Propyn-1-yl)cytidine; Cytidine, 5-(1-propynyl)-; 5-(1-Propynyl)-cytidine

5-(1-Propynyl)uridine

Description: 5-(1-Propynyl)uridine is a modified nucleoside where a propynyl group (-C≡CH) is attached to the 5-position of the uridine base. This modification can influence the base-pairing properties and interactions of the nucleoside, making it useful for various biochemical and medicinal applications, including RNA modification studies and the development of nucleic acid-based therapeutics.
CAT: BRP-01401
CAS: 188254-39-9
Molecular Formula: C12H14N2O6
Molecular Weight: 282.25
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Density: 1.61±0.1 g/cm3
InChIKey: QLOCVMVCRJOTTM-TURQNECASA-N
CanonicalSMILES: CC#CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione
InChI: InChI=1S/C12H14N2O6/c1-2-3-6-4-14(12(19)13-10(6)18)11-9(17)8(16)7(5-15)20-11/h4,7-9,11,15-17H,5H2,1H3,(H,13,18,19)/t7-,8-,9-,11-/m1/s1
Synonyms: 5-Propynyl-ribo Uridine; 5-(1-Propyn-1-yl)uridine; Uridine, 5-(1-propynyl)-; 5-Propynyl-uridine; 5-Propynyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(prop-1-yn-1-yl)pyrimidine-2,4(1H,3H)-dione

ribo Isoguanosine (n,n-diisobutylformamidine)

Description: ribo Isoguanosine (n,n-diisobutylformamidine) is a modified form of guanosine used in nucleic acid chemistry and molecular biology research. It features a ribose sugar backbone and a modified guanine base with N,N-diisobutylformamidine. This modification alters the properties of the nucleoside, potentially affecting base pairing and stability in nucleic acid structures. Ribose Isoguanosine finds applications in various areas, including RNA modification studies, nucleic acid labeling, and as a probe in molecular biology assays.
CAT: BRP-01461
Molecular Formula: C19H30N6O5
Molecular Weight: 422.48
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InChIKey: YPOHJXMARJLOJQ-SCFUHWHPSA-N
IUPAC Name: N,N-dibutyl-N'-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-3,9-dihydro-2H-purin-6-yl)formimidamide
InChI: InChI=1S/C19H30N6O5/c1-3-5-7-24(8-6-4-2)10-21-16-13-17(23-19(29)22-16)25(11-20-13)18-15(28)14(27)12(9-26)30-18/h10-12,14-15,18,26-28H,3-9H2,1-2H3,(H,22,23,29)/t12-,14-,15-,18-/m1/s1
Synonyms: Ribose Isoguanosine (N,N-diisobutylformamidine)

N-Isobutyrylcytidine

Description: N-Isobutyrylcytidine is a modified form of cytidine used in nucleic acid research and synthesis. It features a cytidine base with an isobutyryl group attached to the amine group of the nucleobase. This modification alters the properties of cytidine and can affect its base pairing and stability in nucleic acid structures. N-Isobutyrylcytidine finds applications in various molecular biology techniques, such as oligonucleotide synthesis, RNA modification studies, and nucleic acid labeling.
CAT: BRP-01462
CAS: 60107-05-3
Molecular Formula: C13H19N3O6
Molecular Weight: 313.31
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Density: 1.59±0.1 g/cm3
InChIKey: QNCJITIARBTMOQ-UGKPPGOTSA-N
CanonicalSMILES: CC(C)C(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)O)O
IUPAC Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]-2-methylpropanamide
InChI: InChI=1S/C13H19N3O6/c1-6(2)11(20)14-8-3-4-16(13(21)15-8)12-10(19)9(18)7(5-17)22-12/h3-4,6-7,9-10,12,17-19H,5H2,1-2H3,(H,14,15,20,21)/t7-,9-,10-,12-/m1/s1
Synonyms: ribo Cytidine (n-ibu); N-(2-Methyl-1-oxopropyl)cytidine; N-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)isobutyramide; N4-Isobutyrylcytidine

N-Phenoxyacetylcytidine

Description: N-Phenoxyacetylcytidine is a modified form of cytidine used in nucleic acid research and synthesis. It contains a cytidine base with a phenoxyacetyl group attached to the amine group of the nucleobase. This modification alters the properties of cytidine and can influence its base pairing and stability in nucleic acid structures. N-Phenoxyacetylcytidine finds applications in various molecular biology techniques, including oligonucleotide synthesis, RNA modification studies, and nucleic acid labeling.
CAT: BRP-01463
CAS: 124345-56-8
Molecular Formula: C17H19N3O7
Molecular Weight: 377.35
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Density: 1.57±0.1 g/cm3
Melting Point: 180-182 °C
InChIKey: SWPJUNUVFHWYME-RAEVTNRLSA-N
CanonicalSMILES: C1=CC=C(C=C1)OCC(=O)NC2=NC(=O)N(C=C2)C3C(C(C(O3)CO)O)O
IUPAC Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]-2-phenoxyacetamide
InChI: InChI=1S/C17H19N3O7/c21-8-11-14(23)15(24)16(27-11)20-7-6-12(19-17(20)25)18-13(22)9-26-10-4-2-1-3-5-10/h1-7,11,14-16,21,23-24H,8-9H2,(H,18,19,22,25)/t11-,14-,15-,16-/m1/s1
Synonyms: ribo Cytidine (n-PAC); N4-Phenoxyacetylcytidine; Cytidine, N-(phenoxyacetyl)-; N-(2-Phenoxyacetyl)cytidine; N-(Phenoxyacetyl)cytidine

3',5'-O-DTBS-2'-O-TBDMS-N4-Ac-rC

Description: 3',5'-O-DTBS-2'-O-TBDMS-N4-Ac-rC is a modified cytidine nucleoside used in oligonucleotide synthesis. It is characterized by protective groups such as di-tert-butylsilyl (DTBS) at the 3' and 5' hydroxyl positions, a tert-butyldimethylsilyl (TBDMS) group at the 2' hydroxyl position, and an acetyl group at the N4 position of the cytidine base. These modifications enhance stability and protection during the synthesis process, facilitating the precise and efficient assembly of oligonucleotides for various applications in molecular biology and biotechnology.
CAT: BRP-01488
CAS: 401812-96-2
Molecular Formula: C25H45N3O6Si2
Molecular Weight: 539.81
Purity: ≥97%
Appearance: White to off-white powder
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Density: 1.13±0.1 g/cm3
InChIKey: DYKRNVAKLAJPHD-CWJKEVGVSA-N
CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C3C(O2)CO[Si](O3)(C(C)(C)C)C(C)(C)C)O[Si](C)(C)C(C)(C)C
IUPAC Name: N-[1-[(4aR,6R,7R,7aR)-2,2-ditert-butyl-7-[tert-butyl(dimethyl)silyl]oxy-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxasilin-6-yl]-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C25H45N3O6Si2/c1-16(29)26-18-13-14-28(22(30)27-18)21-20(33-35(11,12)23(2,3)4)19-17(32-21)15-31-36(34-19,24(5,6)7)25(8,9)10/h13-14,17,19-21H,15H2,1-12H3,(H,26,27,29,30)/t17-,19-,20-,21-/m1/s1
Synonyms: Cytidine, N-acetyl-3',5'-O-[bis(1,1-dimethylethyl)silylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 3',5'-O-DTBS-2'-O-TBDMS-N4-Acetyl-Cytidine; N-Acetyl-3',5'-O-[bis(1,1-dimethylethyl)silylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]cytidine

3',5'-O-DTBS-2'-O-TBDMS-N6-Bz-rA

Description: 3',5'-O-DTBS-2'-O-TBDMS-N6-Bz-rA is a modified adenosine nucleoside used in oligonucleotide synthesis. It features protective groups, including di-tert-butylsilyl (DTBS) at the 3' and 5' hydroxyl positions, tert-butyldimethylsilyl (TBDMS) at the 2' hydroxyl position, and a benzoyl (Bz) group at the N6 position of the adenine base. These modifications provide stability and protection during synthesis, ensuring precise and efficient assembly of oligonucleotides for various molecular biology and biotechnology applications.
CAT: BRP-01489
CAS: 401812-98-4
Molecular Formula: C31H47N5O5Si2
Molecular Weight: 625.91
Purity: ≥97%
Appearance: White to off-white powder
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Density: 1.19±0.1 g/cm3
Melting Point: 127-128 °C
InChIKey: KJCFCWKXNODZCR-WBMMKZCBSA-N
CanonicalSMILES: CC(C)(C)[Si]1(OCC2C(O1)C(C(O2)N3C=NC4=C(N=CN=C43)NC(=O)C5=CC=CC=C5)O[Si](C)(C)C(C)(C)C)C(C)(C)C
IUPAC Name: N-[9-[(4aR,6R,7R,7aR)-2,2-ditert-butyl-7-[tert-butyl(dimethyl)silyl]oxy-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxasilin-6-yl]purin-6-yl]benzamide
InChI: InChI=1S/C31H47N5O5Si2/c1-29(2,3)42(10,11)40-24-23-21(17-38-43(41-23,30(4,5)6)31(7,8)9)39-28(24)36-19-34-22-25(32-18-33-26(22)36)35-27(37)20-15-13-12-14-16-20/h12-16,18-19,21,23-24,28H,17H2,1-11H3,(H,32,33,35,37)/t21-,23-,24-,28-/m1/s1
Synonyms: Adenosine, N-benzoyl-3',5'-O-[bis(1,1-dimethylethyl)silylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 3',5'-O-Bis(t-butylsilyl)-2'-O-(t-butyldimethylsilyl)-N6-benzoyladenosine

3',5'-O-DTBS-2'-O-TBDMS-N2-ibu-rG

Description: 3',5'-O-DTBS-2'-O-TBDMS-N2-ibu-rG is a modified guanosine nucleoside used in oligonucleotide synthesis. It contains protective groups, including di-tert-butylsilyl (DTBS) at the 3' and 5' hydroxyl positions, tert-butyldimethylsilyl (TBDMS) at the 2' hydroxyl position, and an isobutyryl (ibu) group at the N2 position of the guanine base. These modifications ensure stability and protection during the synthesis process, allowing for precise and efficient assembly of oligonucleotides for various applications in molecular biology and biotechnology.
CAT: BRP-01490
CAS: 401813-00-1
Molecular Formula: C28H49N5O6Si2
Molecular Weight: 607.89
Purity: ≥97%
Appearance: White to off-white powder
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Density: 1.21±0.1 g/cm3
InChIKey: UCNRPVSECIYJFT-AGFSROSKSA-N
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C4C(O3)CO[Si](O4)(C(C)(C)C)C(C)(C)C)O[Si](C)(C)C(C)(C)C
IUPAC Name: N-[9-[(4aR,6R,7R,7aR)-2,2-ditert-butyl-7-[tert-butyl(dimethyl)silyl]oxy-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxasilin-6-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C28H49N5O6Si2/c1-16(2)22(34)31-25-30-21-18(23(35)32-25)29-15-33(21)24-20(38-40(12,13)26(3,4)5)19-17(37-24)14-36-41(39-19,27(6,7)8)28(9,10)11/h15-17,19-20,24H,14H2,1-13H3,(H2,30,31,32,34,35)/t17-,19-,20-,24-/m1/s1
Synonyms: Guanosine, 3',5'-O-[bis(1,1-dimethylethyl)silylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-; 3',5'-O-DTBS-2'-O-TBDMS-N2-isobutyryl-Guanosine

3',5'-O-DTBS-2'-O-TBDMS-rA

Description: 3',5'-O-DTBS-2'-O-TBDMS-rA is a chemically modified adenosine nucleoside used in oligonucleotide synthesis. It is characterized by protective groups, including di-tert-butylsilyl (DTBS) groups at both the 3' and 5' hydroxyl positions, and a tert-butyldimethylsilyl (TBDMS) group at the 2' hydroxyl position of the ribose sugar. These modifications help protect the nucleoside during synthesis, ensuring stability and precision in the creation of oligonucleotides for various applications in molecular biology and biotechnology.
CAT: BRP-01491
CAS: 212375-93-4
Molecular Formula: C24H43N5O4Si2
Molecular Weight: 521.80
Purity: ≥97%
Appearance: White to off-white powder
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Density: 1.19±0.1 g/cm3
Melting Point: 191-193.4 °C
Boiling Point: 578.2±60.0 °C at 760 mmHg
InChIKey: NKVFXNVWNYNCJM-QTQZEZTPSA-N
CanonicalSMILES: CC(C)(C)[Si]1(OCC2C(O1)C(C(O2)N3C=NC4=C(N=CN=C43)N)O[Si](C)(C)C(C)(C)C)C(C)(C)C
IUPAC Name: 9-[(4aR,6R,7R,7aR)-2,2-ditert-butyl-7-[tert-butyl(dimethyl)silyl]oxy-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxasilin-6-yl]purin-6-amine
InChI: InChI=1S/C24H43N5O4Si2/c1-22(2,3)34(10,11)32-18-17-15(12-30-35(33-17,23(4,5)6)24(7,8)9)31-21(18)29-14-28-16-19(25)26-13-27-20(16)29/h13-15,17-18,21H,12H2,1-11H3,(H2,25,26,27)/t15-,17-,18-,21-/m1/s1
Synonyms: Adenosine, 3',5'-O-[bis(1,1-dimethylethyl)silylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 3',5'-O-Bis(t-butylsilyl)-2'-O-(t-butyldimethylsilyl)adenosine

3',5'-O-DTBS-2'-O-TBDMS-rC

Description: 3',5'-O-DTBS-2'-O-TBDMS-rC is a chemically modified cytidine nucleoside used in oligonucleotide synthesis. It features protective groups including di-tert-butylsilyl (DTBS) groups at both the 3' and 5' hydroxyl positions, and a tert-butyldimethylsilyl (TBDMS) group at the 2' hydroxyl position of the ribose sugar. These modifications ensure stability and protection during synthesis, facilitating the creation of high-quality, customized oligonucleotides for various applications in molecular biology and biotechnology.
CAT: BRP-01492
CAS: 438582-96-8
Molecular Formula: C23H43N3O5Si2
Molecular Weight: 497.78
Purity: ≥97%
Appearance: White to off-white powder
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Density: 1.13±0.1 g/cm3
Boiling Point: 519.6±60.0 °C at 760 mmHg
InChIKey: IAERLBNQNFRAMO-NXWXRZEISA-N
CanonicalSMILES: CC(C)(C)[Si]1(OCC2C(O1)C(C(O2)N3C=CC(=NC3=O)N)O[Si](C)(C)C(C)(C)C)C(C)(C)C
IUPAC Name: 1-[(4aR,6R,7R,7aR)-2,2-ditert-butyl-7-[tert-butyl(dimethyl)silyl]oxy-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxasilin-6-yl]-4-aminopyrimidin-2-one
InChI: InChI=1S/C23H43N3O5Si2/c1-21(2,3)32(10,11)30-18-17-15(29-19(18)26-13-12-16(24)25-20(26)27)14-28-33(31-17,22(4,5)6)23(7,8)9/h12-13,15,17-19H,14H2,1-11H3,(H2,24,25,27)/t15-,17-,18-,19-/m1/s1
Synonyms: Cytidine, 3',5'-O-[bis(1,1-dimethylethyl)silylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 3',5'-O-[Bis(1,1-dimethylethyl)silylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]cytidine

3',5'-O-DTBS-2'-O-TBDMS-rU

Description: 3',5'-O-DTBS-2'-O-TBDMS-rU is a chemically modified uridine nucleoside used in oligonucleotide synthesis. It is characterized by protective groups, including di-tert-butylsilyl (DTBS) groups at both the 3' and 5' hydroxyl positions, and a tert-butyldimethylsilyl (TBDMS) group at the 2' hydroxyl position of the ribose sugar. These modifications protect the nucleoside during synthesis, ensuring stability and precision in the creation of oligonucleotides for various applications in molecular biology and biotechnology.
CAT: BRP-01493
CAS: 212375-92-3
Molecular Formula: C23H42N2O6Si2
Molecular Weight: 498.76
Purity: ≥97%
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Density: 1.11±0.1 g/cm3
InChIKey: HWUBERHQHCSGOU-NXWXRZEISA-N
CanonicalSMILES: CC(C)(C)[Si]1(OCC2C(O1)C(C(O2)N3C=CC(=O)NC3=O)O[Si](C)(C)C(C)(C)C)C(C)(C)C
IUPAC Name: 1-[(4aR,6R,7R,7aR)-2,2-ditert-butyl-7-[tert-butyl(dimethyl)silyl]oxy-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxasilin-6-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C23H42N2O6Si2/c1-21(2,3)32(10,11)30-18-17-15(29-19(18)25-13-12-16(26)24-20(25)27)14-28-33(31-17,22(4,5)6)23(7,8)9/h12-13,15,17-19H,14H2,1-11H3,(H,24,26,27)/t15-,17-,18-,19-/m1/s1
Synonyms: Uridine, 3',5'-O-[bis(1,1-dimethylethyl)silylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-; 3',5'-O-[Bis(1,1-dimethylethyl)silylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]uridine

5-Ethynyluridine

Description: 5-Ethynyluridine is a modified uridine nucleoside featuring an ethynyl group (-C≡CH) attached to the fifth carbon atom of the uracil base. This modification provides unique properties such as enhanced base stacking interactions and increased stability of nucleic acid structures. It is commonly used in RNA labeling and detection applications, including RNA synthesis, site-specific modification, and click chemistry-mediated conjugation reactions for studying RNA dynamics and function in biological systems.
CAT: BRP-01494
CAS: 69075-42-9
Molecular Formula: C11H12N2O6
Molecular Weight: 268.22
Purity: ≥98%
Appearance: White to off-white powder
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Density: 1.67±0.1 g/cm3
Melting Point: 188-190 °C
InChIKey: QCWBIPKYTBFWHH-FDDDBJFASA-N
CanonicalSMILES: C#CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-ethynylpyrimidine-2,4-dione
InChI: InChI=1S/C11H12N2O6/c1-2-5-3-13(11(18)12-9(5)17)10-8(16)7(15)6(4-14)19-10/h1,3,6-8,10,14-16H,4H2,(H,12,17,18)/t6-,7-,8-,10-/m1/s1
Synonyms: 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpyrimidine-2,4-(1H,3H)-dione; 5-Ethynyl uridine; 5-EU

N6-p-Sulfophenyladenosine sodium salt

Description: N6-p-Sulfophenyladenosine sodium salt is a modified adenosine derivative used extensively in biochemical and pharmacological research. Its unique modification at the N6 position allows for the detailed study of adenosine receptor interactions, signal transduction pathways, and the development of potential therapeutic agents targeting adenosine-related pathways. The addition of the sulfophenyl group can significantly influence its binding properties and biological activities, making it a valuable tool in various research applications.
CAT: BRP-01501
CAS: 1349749-05-8
Molecular Formula: C16H16N5NaO7S
Molecular Weight: 445.38
Purity: ≥95%
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InChIKey: JYEFPEJJPNYEHO-KHXPSBENSA-M
CanonicalSMILES: C1=CC(=CC=C1NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O)S(=O)(=O)[O-].[Na+]
IUPAC Name: sodium;4-[[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]benzenesulfonate
InChI: InChI=1S/C16H17N5O7S.Na/c22-5-10-12(23)13(24)16(28-10)21-7-19-11-14(17-6-18-15(11)21)20-8-1-3-9(4-2-8)29(25,26)27;/h1-4,6-7,10,12-13,16,22-24H,5H2,(H,17,18,20)(H,25,26,27);/q;+1/p-1/t10-,12-,13-,16-;/m1./s1
Synonyms: Benzenesulfonic acid, 4-[(9-β-D-ribofuranosyl-9H-purin-6-yl)amino]-, sodium salt(1:1); N6-(p-Sulfophenyl)adenosine sodium salt; 4-[(9-β-D-Ribofuranosyl-9H-purin-6-yl)amino]benzenesulfonic acid sodium salt; N-(p-Sulfophenyl)adenosine sodium salt
Related CAS: 143668-15-9 (free acid)

6-Chlorouridine

Description: 6-Chlorouridine is a valuable modified nucleoside used in biochemical, pharmacological, and chemical biology research. Its chlorination at the 6-position allows scientists to study the effects of halogenation on nucleotide function, RNA structure, and potential therapeutic applications. This compound provides insights into the role of modified nucleosides in various biological processes and aids in the development of novel therapeutic agents and research tools.
CAT: BRP-01502
CAS: 255723-79-6
Molecular Formula: C9H11ClN2O6
Molecular Weight: 278.65
Purity: ≥95%
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Density: 1.80±0.1 g/cm3
InChIKey: CYMWXTBIGHJEJG-YXZULKJRSA-N
CanonicalSMILES: C1=C(N(C(=O)NC1=O)C2C(C(C(O2)CO)O)O)Cl
IUPAC Name: 6-chloro-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
InChI: InChI=1S/C9H11ClN2O6/c10-4-1-5(14)11-9(17)12(4)8-7(16)6(15)3(2-13)18-8/h1,3,6-8,13,15-16H,2H2,(H,11,14,17)/t3-,6-,7-,8-/m1/s1
Synonyms: 6-chloro-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Adenosine, monohydrochloride

Description: Adenosine monohydrochloride is a hydrochloride salt form of adenosine, a nucleoside composed of adenine and ribose. Adenosine plays a crucial role in biochemical processes such as energy transfer (e.g., ATP) and signal transduction as a neurotransmitter. In its monohydrochloride form, adenosine is more soluble in water, making it useful for various biochemical and pharmaceutical applications. This compound is employed in research focused on cellular metabolism, enzyme functions, and nucleic acid interactions. Additionally, adenosine monohydrochloride is used in studies investigating the effects of adenosine on cardiovascular and neurological functions.
CAT: BRP-01521
CAS: 19065-22-6
Molecular Formula: C10H13N5O4.HCl
Molecular Weight: 303.70
Purity: ≥98% by HPLC
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InChIKey: YFJCRJZTDYDCRZ-MCDZGGTQSA-N
CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N.Cl
IUPAC Name: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol;hydrochloride
InChI: InChI=1S/C10H13N5O4.ClH/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10;/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13);1H/t4-,6-,7-,10-;/m1./s1
Synonyms: Adenosine hydrochloride; Adenosine hydrochloride (1:1); (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol hydrochloride; 9-β-D-Ribofuranosyl-9H-purin-6-amine monohydrochloride; 9-β-D-Ribofuranosyladenine monohydrochloride; D-Adenosine monohydrochloride; Adenine riboside monohydrochloride; β-D-Adenosine monohydrochloride; β-Adenosine monohydrochloride
Related CAS: 58-61-7 (free base) ; 58056-57-8 (x-hydrochloride )

Uridine, monohydrate

Description: Uridine hydrate is a hydrated form of uridine, a nucleoside consisting of uracil attached to a ribose sugar. Uridine is a key component of RNA and plays a significant role in cellular processes, including the synthesis of nucleic acids, glycoproteins, and cell membranes. Uridine hydrate is often used in biochemical and medical research to study RNA synthesis, metabolism, and the effects of nucleosides on cellular functions. It is also investigated for its potential therapeutic benefits in neurological disorders, liver function improvement, and cognitive enhancement. The hydrated form of uridine ensures better solubility and stability for various experimental and clinical applications.
CAT: BRP-01522
CAS: 128475-15-0
Molecular Formula: C9H12N2O6.H2O
Molecular Weight: 262.22
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InChIKey: IDZICQNRCHBMKN-IAIGYFSYSA-N
CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O.O
IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione;hydrate
InChI: InChI=1S/C9H12N2O6.H2O/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16;/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16);1H2/t4-,6-,7-,8-;/m1./s1
Synonyms: Uridine, hydrate (1:1); Uridine hydrate; 1-β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione hydrate; 1-β-D-Ribofuranosyluracil hydrate; β-Uridine hydrate
Related CAS: 58-96-8 (anhydrous) ; 921930-23-6 (dihydrate)

Frequently Asked Questions (FAQ)

What are nucleosides used for?

Nucleosides are base molecules used as starting materials for synthesizing nucleotides and phosphoramidites.

What is the difference between nucleosides and nucleotides?

Nucleosides lack phosphate groups, while nucleotides contain one or more phosphates required for enzymatic reactions.

Are nucleosides used directly in enzymatic reactions?

Nucleosides are typically chemically modified before being used in enzymatic workflows.

Can nucleosides be chemically modified?

Yes, modified nucleosides are widely used to introduce structural or functional changes in nucleic acids.

Why is nucleoside purity important?

High purity ensures correct downstream synthesis of nucleotides and phosphoramidites with predictable performance.

* Only for research. Not suitable for any diagnostic or therapeutic use.

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