Nucleosides

N6-iBu-3',5'-TIPDS-Ar

Description: N6-iBu-3',5'-TIPDS-Ar features an adenosine nucleotide where the nitrogen at position 6 (N6) of the adenine base is protected with an isobutyryl (iBu) group. Similarly, the ribose sugar at positions 3' and 5' is protected with 3',5'-di-tert-isopropylsilyl (TIPDS) groups. This modification is used in oligonucleotide synthesis to introduce modified adenosine residues, ensuring stability and enhancing functionality in nucleic acid applications.

CAT: BRP-01201

CAS: 163774-15-0

Molecular Formula: C26H45N5O6Si2

Molecular Weight: 579.84

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Density: 1.27±0.1 g/cm3

InChIKey: ZYESLHXCOCSGRD-RKCWLVDCSA-N

CanonicalSMILES: CC(C)C(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C4C(O3)CO[Si](O[Si](O4)(C(C)C)C(C)C)(C(C)C)C(C)C)O

IUPAC Name: N-[9-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]purin-6-yl]-2-methylpropanamide

InChI: InChI=1S/C26H45N5O6Si2/c1-14(2)25(33)30-23-20-24(28-12-27-23)31(13-29-20)26-21(32)22-19(35-26)11-34-38(15(3)4,16(5)6)37-39(36-22,17(7)8)18(9)10/h12-19,21-22,26,32H,11H2,1-10H3,(H,27,28,30,33)/t19-,21-,22-,26-/m1/s1

Synonyms: N6-isobutyryl-3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-adenosine; N-(9-((6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-9H-purin-6-yl)isobutyramide; N-(2-Methyl-1-oxopropyl)-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]adenosine

N2-dmf-3',5'-TIPDS-Gr

Description: N2-dmf-3',5'-TIPDS-Gr comprises a guanosine nucleotide where the nitrogen at position 2 (N2) of the guanine base is protected with a dimethylformamide (dmf) group. The ribose sugar at positions 3' and 5' is protected with 3',5'-di-tert-isopropylsilyl (TIPDS) groups. This modification is applied in oligonucleotide synthesis to incorporate modified guanosine residues, ensuring stability and compatibility in various nucleic acid studies.

CAT: BRP-01202

CAS: 120853-22-7

Molecular Formula: C25H44N6O6Si2

Molecular Weight: 580.83

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Density: 1.28±0.1 g/cm3

InChIKey: SQVNAKSYJCMYQC-UMCMBGNQSA-N

CanonicalSMILES: O=C1N=C(N=CN(C)C)NC2=C1N=CN2C3OC4CO[Si](O[Si](OC4C3O)(C(C)C)C(C)C)(C(C)C)C(C)C

IUPAC Name: N'-(9-((6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide

InChI: InChI=1S/C25H44N6O6Si2/c1-14(2)38(15(3)4)34-11-18-21(36-39(37-38,16(5)6)17(7)8)20(32)24(35-18)31-13-26-19-22(31)28-25(29-23(19)33)27-12-30(9)10/h12-18,20-21,24,32H,11H2,1-10H3,(H,28,29,33)/t18-,20-,21-,24-/m1/s1

Synonyms: N2-dimethylformamidine-3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-guanosine; N-[(Dimethylamino)methylene]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine

N4-Bz-3',5'-TIPDS-5-Me-Cr

Description: N4-Bz-3',5'-TIPDS-5-Me-Cr is a modified cytidine nucleotide where the nitrogen at position 4 (N4) of the cytosine base is protected with a benzoyl (Bz) group. Similar to the other compounds, the ribose sugar at positions 3' and 5' is protected with 3',5'-di-tert-isopropylsilyl (TIPDS) groups. This modification is utilized in oligonucleotide synthesis to introduce modified cytidine residues, enhancing stability and specificity for applications in molecular biology, diagnostics, and therapeutics.

CAT: BRP-01203

CAS: 2940859-44-7

Molecular Formula: C29H45N3O7Si2

Molecular Weight: 603.85

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Density: 1.22±0.1 g/cm3

InChIKey: NSDMZZWBUMTBDG-PAHOUZJPSA-N

CanonicalSMILES: O=C1N=C(NC(=O)C=2C=CC=CC2)C(=CN1C3OC4CO[Si](O[Si](OC4C3O)(C(C)C)C(C)C)(C(C)C)C(C)C)C

IUPAC Name: N-(1-((6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide

InChI: InChI=1S/C29H45N3O7Si2/c1-17(2)40(18(3)4)36-16-23-25(38-41(39-40,19(5)6)20(7)8)24(33)28(37-23)32-15-21(9)26(31-29(32)35)30-27(34)22-13-11-10-12-14-22/h10-15,17-20,23-25,28,33H,16H2,1-9H3,(H,30,31,34,35)/t23-,24-,25-,28-/m1/s1

Synonyms: N4-benzoyl-3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-5-methyl-cytidine

5'-O-DMT-2'-O-TBDMS-N6-Acetyl-Adenosine

Description: 5'-O-DMT-2'-O-TBDMS-N6-Acetyl-Adenosine is a modified nucleoside where adenosine is altered with an acetyl group attached to the N6 position. It features protective groups (DMT and TBDMS) on the 5'- and 2'- hydroxyl groups respectively, which enhance stability and solubility in biochemical assays. This modification is useful in RNA synthesis and modification studies, allowing researchers to investigate how specific chemical alterations affect nucleic acid function and interactions with proteins.

CAT: BRP-01221

CAS: 1115247-32-9

Molecular Formula: C39H47N5O7Si

Molecular Weight: 725.92

Purity: ≥97% by HPLC

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Density: 1.23±0.1 g/cm3

InChIKey: VDNBCIWKZZGQST-SPBWOXKUSA-N

CanonicalSMILES: O=C(NC1=NC=NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(O)C3O[Si](C)(C)C(C)(C)C)C

IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)acetamide

InChI: InChI=1S/C39H47N5O7Si/c1-25(45)43-35-32-36(41-23-40-35)44(24-42-32)37-34(51-52(7,8)38(2,3)4)33(46)31(50-37)22-49-39(26-12-10-9-11-13-26,27-14-18-29(47-5)19-15-27)28-16-20-30(48-6)21-17-28/h9-21,23-24,31,33-34,37,46H,22H2,1-8H3,(H,40,41,43,45)/t31-,33-,34-,37-/m1/s1

Synonyms: N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosine; N6-Acetyl-2'-O-(tert-butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-adenosine

5'-O-DMT-2'-OMe-G(dmf)-3'-O-succinate, TEA salt

Description: 5'-O-DMT-2'-OMe-G(dmf)-3'-O-succinate, TEA salt is a nucleoside analog that has a guanosine (G) base with a 2'-OMe modification and a succinate group at the 3'-position. The TEA (triethylamine) salt form ensures improved solubility and stability in aqueous solutions, making it suitable for biochemical research involving RNA structure and function. This compound is valuable for probing RNA-protein interactions and studying enzymatic processes that involve guanosine derivatives.

CAT: BRP-01222

Molecular Formula: C39H42N6O10 (free acid)

Molecular Weight: 754.80 (free acid)

Purity: ≥98% by HPLC

Appearance: White to yellow powder

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IUPAC Name: 4-(((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-((dimethylamino)methylene)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: N2-dimethylformamide-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-guanosine 3'-O-succinate, triethylamine salt; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-methyl-, 3'-(hydrogen butanedioate), triethylamine salt

Related CAS: 143028-80-2 (free base)

N4-Bz-DMT-2'-O-Me-Cr-3'-succinate, TEA salt

Description: N4-Bz-DMT-2'-O-Me-Cr-3'-succinate, TEA salt, a nucleoside derivative, contains a cytosine (C) base modified with a benzoyl (Bz) group at the N4 position and a methyl group (Me) at the 2'-position. The succinate and TEA salt formulation enhances solubility and ease of handling in experimental settings. It is commonly employed in nucleic acid synthesis research to explore the impact of chemical modifications on RNA stability, structure, and function, particularly in the context of RNA-protein interactions.

CAT: BRP-01223

Molecular Formula: C42H41N3O11 (free acid)

Molecular Weight: 763.79 (free acid)

Purity: ≥98% by HPLC

Appearance: White to yellow powder

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IUPAC Name: 4-[(2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine-3'-O-succinate, triethylamine salt; DMT-2'-O-Me-C(Bz)-3'-succinate, TEA salt

Related CAS: 2940874-28-0 (free base)

DMT-2'-O-Me-Ur-3'-succinate, TEA salt

Description: DMT-2'-O-Me-Ur-3'-succinate, TEA salt is a uridine (U) nucleoside derivative featuring a methyl group (Me) at the 2'-position and a succinate group at the 3'-position, stabilized with TEA salt. It is utilized in biochemical studies to investigate RNA biology and nucleoside chemistry. Its structure allows researchers to explore how modifications at the 2'-position of uridine affect RNA structure, stability, and interactions with proteins, providing insights into cellular processes and potential therapeutic targets.

CAT: BRP-01224

Molecular Formula: C35H36N2O11 (free acid)

Molecular Weight: 660.67 (free acid)

Purity: ≥98% by HPLC

Appearance: White to yellow powder

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IUPAC Name: 4-[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-uridine-3'-O-succinate, triethylamine salt

Related CAS: 114745-30-1 (free base) ; 1792211-00-7 (TEA salt (1:1))

N2-iBu-DMT-2'-O-Me-Gr-3'-succinate, TEA salt

Description: N2-iBu-DMT-2'-O-Me-Gr-3'-succinate, TEA salt is a nucleoside analog that comprises guanosine (G) with an isobutyl (iBu) group at the N2 position and a methyl group (Me) at the 2'-position, along with a succinate group stabilized by TEA salt. It is employed in biochemical and molecular biology research to study nucleoside modifications and their impact on RNA function. This compound is valuable for exploring guanosine derivatives' roles in RNA metabolism, structure, and enzymatic reactions involved in nucleic acid synthesis and modification.

CAT: BRP-01225

Molecular Formula: C40H43N5O11 (free acid)

Molecular Weight: 769.80 (free acid)

Purity: ≥98% by HPLC

Appearance: White to yellow powder

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IUPAC Name: 4-[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxy-5-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylguanosine-3'-O-succinate, triethylamine salt; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-, 3'-(hydrogen butanedioate), triethylamine salt; DMT-2'-O-Me-G(iBu)-3'-succinate, TEA salt

Related CAS: 114745-31-2 (free base)

N6-Bz-DMT-2'-O-Me-Ar-3'-succinate, TEA salt

Description: N6-Bz-DMT-2'-O-Me-Ar-3'-succinate, TEA salt is an adenosine (A) derivative that features a benzoyl (Bz) group at the N6 position and a methyl group (Me) at the 2'-position, with succinate and TEA salt for solubility. It is utilized in biochemical and molecular biology studies to investigate modified nucleosides' effects on RNA structure and function. Researchers use this compound to explore how specific chemical modifications at critical positions of adenosine affect RNA-protein interactions, enzymatic processes, and cellular signaling pathways.

CAT: BRP-01226

Molecular Formula: C43H41N5O8 (free acid)

Molecular Weight: 787.81 (free acid)

Purity: ≥98% by HPLC

Appearance: White to yellow powder

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IUPAC Name: 4-[(2R,3R,4R,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-adenosine-3'-O-succinate, triethylamine salt; DMT-2'-O-Me-A(Bz)-3'-succinate, TEA salt

Related CAS: 2940857-85-0 (free base)

5'-O-DMTr-2'-O-MOE-5-Me-C(Bz)-3'-O-succinate, TEA salt

Description: 5'-O-DMTr-2'-O-MOE-5-Me-C(Bz)-3'-O-succinate, TEA salt is a modified nucleoside that contains a cytosine (C) base substituted with a 5-Me-C(Bz) group and a 2'-position methoxyethyl (MOE) modification, with succinate and TEA salt to improve solubility. It is used in synthetic biology and RNA research to investigate nucleoside structure-function relationships and their roles in biological processes. This compound allows researchers to study how specific chemical modifications impact RNA stability, secondary structure formation, and interactions with proteins, advancing our understanding of nucleic acid biochemistry and potential therapeutic applications.

CAT: BRP-01227

Molecular Formula: C45H47N3O12 (free acid)

Molecular Weight: 821.88 (free acid)

Purity: ≥98% by HPLC

Appearance: White to yellow powder

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IUPAC Name: 4-(((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: N4-benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine-3'-O-succinate, triethylamine salt; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-(hydrogen butanedioate), triethylamine salt

Related CAS: 1536204-26-8 (free base) ; 1536204-27-9 (TEA salt (1:1))

5'-DMT-2'-O-MOE-C(Ac)-3'-succinate, TEA salt

Description: 5'-DMT-2'-O-MOE-C(Ac)-3'-succinate, TEA salt is a nucleoside derivative that features a cytosine (C) base modified with an acetyl (Ac) group at the 2'-position and a succinate group at the 3'-position. The TEA (triethylamine) salt formulation ensures improved solubility and stability in aqueous solutions. This compound is used in biochemical research to study RNA structure and function, particularly in exploring how modifications at specific nucleoside positions affect RNA-protein interactions and enzymatic processes.

CAT: BRP-01228

Molecular Formula: C45H58N4O12

Molecular Weight: 846.97

Purity: ≥98% by HPLC

Appearance: White to yellow powder

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InChIKey: GISCEWMZFVCQKL-WKHDLHBGSA-N

CanonicalSMILES: CCN(CC)CC.CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OC(=O)CCC(=O)O)OCCOC

IUPAC Name: 4-[(2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-(2-methoxyethoxy)oxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

InChI: InChI=1S/C39H43N3O12.C6H15N/c1-25(43)40-32-20-21-42(38(47)41-32)37-36(51-23-22-48-2)35(54-34(46)19-18-33(44)45)31(53-37)24-52-39(26-8-6-5-7-9-26,27-10-14-29(49-3)15-11-27)28-12-16-30(50-4)17-13-28;1-4-7(5-2)6-3/h5-17,20-21,31,35-37H,18-19,22-24H2,1-4H3,(H,44,45)(H,40,41,43,47);4-6H2,1-3H3/t31-,35-,36-,37-;/m1./s1

Synonyms: N4-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine-3'-O-succinate, triethylamine salt; Triethylamine 4-(((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoate

5'-O-DMT-2'-O-MOE-U-3'-succinate, TEA salt

Description: 5'-O-DMT-2'-O-MOE-U-3'-succinate, TEA salt is a nucleoside analog that contains a uridine (U) base with a methoxyethyl (MOE) modification at the 2'-position and a succinate group at the 3'-position, stabilized with TEA salt. It is utilized in nucleic acid synthesis and modification studies to investigate the impact of chemical modifications on RNA stability and structure. Researchers use this compound to explore how modifications at the 2'-position of uridine influence RNA function and interactions with proteins.

CAT: BRP-01229

Molecular Formula: C37H40N2O12 (free acid)

Molecular Weight: 704.73 (free acid)

Purity: ≥98% by HPLC

Appearance: White to yellow powder

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IUPAC Name: 4-[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-(2-methoxyethoxy)oxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-uridine 3'-O-succinate, triethylamine salt

5'-O-DMT-2'-O-MOE-A(Bz)-3'-O-succinate, TEA salt

Description: 5'-O-DMT-2'-O-MOE-A(Bz)-3'-O-succinate, TEA salt is an adenosine (A) derivative that features a benzoyl (Bz) group at the 2'-position and a methoxyethyl (MOE) modification at the 2'-position, with a succinate group at the 3'-position and stabilized with TEA salt. It is employed in biochemical research to investigate modified nucleosides' effects on RNA structure, stability, and function. This compound is valuable for studying adenosine derivatives' roles in RNA metabolism, enzymatic processes, and interactions with RNA-binding proteins.

CAT: BRP-01230

Molecular Formula: C45H45N5O11 (free acid)

Molecular Weight: 831.88 (free acid)

Purity: ≥98% by HPLC

Appearance: White to yellow powder

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IUPAC Name: 4-[(2R,3R,4R,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-(2-methoxyethoxy)oxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine 3'-O-succinate, triethylamine salt

Related CAS: 444814-78-2 (free base)

5'-O-DMTr-2'-O-TMBTM-C(Bz)-3'-O-succinate, TEA salt

Description: 5'-O-DMTr-2'-O-TMBTM-C(Bz)-3'-O-succinate, TEA salt is a nucleoside derivative that contains a cytosine (C) base modified with a benzoyl (Bz) group at the 2'-position and a TMBTM group at the 2'-position, with a succinate group at the 3'-position and stabilized with TEA salt. It is used in nucleic acid synthesis and modification research to explore the impact of chemical modifications on RNA structure and function. This compound allows researchers to study how specific modifications at critical positions of cytosine influence RNA-protein interactions and enzymatic activities.

CAT: BRP-01231

Molecular Formula: C52H53N3O14S (free acid)

Molecular Weight: 976.06 (free acid)

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at -20 °C

IUPAC Name: 4-(((2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2,4,6-trimethoxybenzyl)thio)methoxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2,4,6-trimethoxybenzylthiomethyl)-cytidine-3'-O-succinate, triethylamine salt

5'-O-DMTr-2'-O-TMBTM-G(iBu)-3'-O-succinate, TEA salt

Description: 5'-O-DMTr-2'-O-TMBTM-G(iBu)-3'-O-succinate, TEA salt is a guanosine (G) nucleoside analog that is modified with an isobutyl (iBu) group at the 2'-position and a TMBTM group at the 2'-position, with a succinate group at the 3'-position and stabilized with TEA salt. It is utilized in biochemical and molecular biology research to investigate modified nucleosides' effects on RNA structure and function. Researchers use this compound to explore how modifications at the 2'-position of guanosine impact RNA stability, enzymatic reactions, and interactions with RNA-binding proteins.

CAT: BRP-01232

Molecular Formula: C50H55N5O14S (free acid)

Molecular Weight: 982.07 (free acid)

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at -20 °C

IUPAC Name: 4-(((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(((2,4,6-trimethoxybenzyl)thio)methoxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2,4,6-trimethoxybenzylthiomethyl)-guanosine-3'-O-succinate, triethylamine salt

5'-O-DMTr-2'-O-TMBTM-U-3'-O-succinate, TEA salt

Description: 5'-O-DMTr-2'-O-TMBTM-U-3'-O-succinate, TEA salt is a uridine (U) nucleoside derivative that features a TMBTM modification at the 2'-position and a succinate group at the 3'-position, stabilized with TEA salt. It is used in nucleic acid research to study RNA modifications and their impact on RNA biology. This compound allows researchers to investigate how modifications at the 2'-position of uridine affect RNA structure, stability, and interactions with proteins, providing insights into cellular processes and potential therapeutic applications.

CAT: BRP-01233

Molecular Formula: C45H48N2O14S (free acid)

Molecular Weight: 872.94 (free acid)

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at 2-8 °C

IUPAC Name: 4-(((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-(((2,4,6-trimethoxybenzyl)thio)methoxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2,4,6-trimethoxybenzylthiomethyl)-uridine-3'-O-succinate, triethylamine salt

5'-O-DMTr-2'-O-TMBTM-A(Bz)-3'-O-succinate, TEA salt

Description: 5'-O-DMTr-2'-O-TMBTM-A(Bz)-3'-O-succinate, TEA salt is an adenosine (A) derivative that contains a benzoyl (Bz) group at the 2'-position and a TMBTM modification at the 2'-position, with a succinate group at the 3'-position and stabilized with TEA salt. It is employed in biochemical and molecular biology research to study nucleoside modifications and their impact on RNA function. This compound allows researchers to explore how modifications at the 2'-position of adenosine influence RNA metabolism, structure, and interactions with proteins involved in RNA processing and regulation.

CAT: BRP-01234

Molecular Formula: C53H53N5O13S (free acid)

Molecular Weight: 1000.09 (free acid)

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at -20 °C

IUPAC Name: 4-(((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2,4,6-trimethoxybenzyl)thio)methoxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine

Synonyms: N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2,4,6-trimethoxybenzylthiomethyl)-adenosine-3'-O-succinate, triethylamine salt

5'-O-DMTr-2'-O-TOM-U succinate

Description: 5'-O-DMTr-2'-O-TOM-U succinate is a nucleoside derivative that features a uridine (U) base with a TOM (2'-O-TOM) modification at the 2'-position and a succinate group at the 3'-position. It is used in nucleic acid synthesis and modification studies to investigate the role of modified nucleosides in RNA structure and function. The succinate modification aids in enhancing solubility and stability in biochemical assays, making it suitable for studying RNA-protein interactions and enzymatic activities involved in RNA metabolism.

CAT: BRP-01235

Molecular Formula: C44H56N2O12Si

Molecular Weight: 833.02

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at -20 °C

InChIKey: TWSPHFOHWURPEH-GLONBZIJSA-N

IUPAC Name: 4-(((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-(((triisopropylsilyl)oxy)methoxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid

InChI: InChI=1S/C44H56N2O12Si/c1-28(2)59(29(3)4,30(5)6)56-27-54-41-40(58-39(50)23-22-38(48)49)36(57-42(41)46-25-24-37(47)45-43(46)51)26-55-44(31-12-10-9-11-13-31,32-14-18-34(52-7)19-15-32)33-16-20-35(53-8)21-17-33/h9-21,24-25,28-30,36,40-42H,22-23,26-27H2,1-8H3,(H,48,49)(H,45,47,51)/t36-,40-,41-,42-/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-triisopropylsilyloxymethyl-uridine-succinate; 5'-O-DMTr-2'-O-TOM-U-3'-O-succinate

5'-O-DMTr-2'-O-TOM-C(Ac) succinate

Description: 5'-O-DMTr-2'-O-TOM-C(Ac) succinate is a cytosine (C) nucleoside analog that contains an acetyl (Ac) group at the 2'-position and a TOM (2'-O-TOM) modification at the 2'-position, with a succinate group at the 3'-position. It is utilized in biochemical research to explore modified nucleosides' effects on RNA stability and function. This compound allows researchers to investigate how modifications at the 2'-position of cytosine influence RNA structure, enzymatic processes, and interactions with proteins, advancing our understanding of nucleic acid biochemistry and potential therapeutic applications.

CAT: BRP-01236

Molecular Formula: C46H59N3O12Si

Molecular Weight: 874.07

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at -20 °C

InChIKey: AQUZVAWRHRMGSV-LAYMWRTISA-N

IUPAC Name: 4-(((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((triisopropylsilyl)oxy)methoxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid

InChI: InChI=1S/C46H59N3O12Si/c1-29(2)62(30(3)4,31(5)6)59-28-57-43-42(61-41(53)24-23-40(51)52)38(60-44(43)49-26-25-39(47-32(7)50)48-45(49)54)27-58-46(33-13-11-10-12-14-33,34-15-19-36(55-8)20-16-34)35-17-21-37(56-9)22-18-35/h10-22,25-26,29-31,38,42-44H,23-24,27-28H2,1-9H3,(H,51,52)(H,47,48,50,54)/t38-,42-,43-,44-/m1/s1

Synonyms: N4-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-triisopropylsilyloxymethyl-cytidine-succinate; 5'-O-DMTr-2'-O-TOM-C(Ac)-3'-O-succinate

5'-O-DMTr-2'-O-TOM-A(Ac) succinate

Description: 5'-O-DMTr-2'-O-TOM-A(Ac) succinate is an adenosine (A) nucleoside derivative featuring an acetyl (Ac) group at the 2'-position and a TOM (2'-O-TOM) modification at the 2'-position, with a succinate group at the 3'-position. This derivative is used in nucleic acid research to study RNA modifications and their impact on RNA structure and function. It allows researchers to explore how modifications at specific positions of adenosine affect RNA stability, enzymatic processes, and interactions with RNA-binding proteins.

CAT: BRP-01237

Molecular Formula: C47H59N5O11Si

Molecular Weight: 898.10

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at -20 °C

InChIKey: BWTSLHAPYYEBNJ-LSWBLBMOSA-N

IUPAC Name: 4-(((2R,3R,4R,5R)-5-(6-acetamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((triisopropylsilyl)oxy)methoxy)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid

InChI: InChI=1S/C47H59N5O11Si/c1-29(2)64(30(3)4,31(5)6)61-28-59-43-42(63-40(56)24-23-39(54)55)38(62-46(43)52-27-50-41-44(51-32(7)53)48-26-49-45(41)52)25-60-47(33-13-11-10-12-14-33,34-15-19-36(57-8)20-16-34)35-17-21-37(58-9)22-18-35/h10-22,26-27,29-31,38,42-43,46H,23-25,28H2,1-9H3,(H,54,55)(H,48,49,51,53)/t38-,42-,43-,46-/m1/s1

Synonyms: N6-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-triisopropylsilyloxymethyl-adenosine-succinate; 5'-O-DMTr-2'-O-TOM-A(Ac)-3'-O-succinate

N6-iBu-3',5'-TIPDS-Ar

N2-dmf-3',5'-TIPDS-Gr

N4-Bz-3',5'-TIPDS-5-Me-Cr

5'-O-DMT-2'-O-TBDMS-N6-Acetyl-Adenosine

5'-O-DMT-2'-OMe-G(dmf)-3'-O-succinate, TEA salt

N4-Bz-DMT-2'-O-Me-Cr-3'-succinate, TEA salt

DMT-2'-O-Me-Ur-3'-succinate, TEA salt

N2-iBu-DMT-2'-O-Me-Gr-3'-succinate, TEA salt

N6-Bz-DMT-2'-O-Me-Ar-3'-succinate, TEA salt

5'-O-DMTr-2'-O-MOE-5-Me-C(Bz)-3'-O-succinate, TEA salt

5'-DMT-2'-O-MOE-C(Ac)-3'-succinate, TEA salt

5'-O-DMT-2'-O-MOE-U-3'-succinate, TEA salt

5'-O-DMT-2'-O-MOE-A(Bz)-3'-O-succinate, TEA salt

5'-O-DMTr-2'-O-TMBTM-C(Bz)-3'-O-succinate, TEA salt

5'-O-DMTr-2'-O-TMBTM-G(iBu)-3'-O-succinate, TEA salt

5'-O-DMTr-2'-O-TMBTM-U-3'-O-succinate, TEA salt

5'-O-DMTr-2'-O-TMBTM-A(Bz)-3'-O-succinate, TEA salt

5'-O-DMTr-2'-O-TOM-U succinate

5'-O-DMTr-2'-O-TOM-C(Ac) succinate

5'-O-DMTr-2'-O-TOM-A(Ac) succinate

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