What are nucleosides used for?

Nucleosides are base molecules used as starting materials for synthesizing nucleotides and phosphoramidites.

What is the difference between nucleosides and nucleotides?

Nucleosides lack phosphate groups, while nucleotides contain one or more phosphates required for enzymatic reactions.

Are nucleosides used directly in enzymatic reactions?

Nucleosides are typically chemically modified before being used in enzymatic workflows.

Can nucleosides be chemically modified?

Yes, modified nucleosides are widely used to introduce structural or functional changes in nucleic acids.

Why is nucleoside purity important?

High purity ensures correct downstream synthesis of nucleotides and phosphoramidites with predictable performance.

Nucleosides - RNA / BOC Sciences

9-(2'-Fluoro-2'-deoxy-β-L-arabinofuranosyl)adenine

Description: 9-(2'-Fluoro-2'-deoxy-β-L-arabinofuranosyl)adenine is a modified nucleoside where adenine is attached to a β-L-arabinofuranosyl sugar with a 2'-fluoro-2'-deoxy modification at the ribose. This modification enhances the stability and alters the chemical properties of the nucleoside, making it useful in nucleic acid chemistry for applications such as nucleotide analog synthesis and structural studies.

CAT: BRP-01593

CAS: 193754-07-3

Molecular Formula: C10H12FN5O3

Molecular Weight: 269.23

Purity: ≥98%

Appearance: White to off-white powder

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Density: 2.01±0.1 g/cm3

Boiling Point: 628.6±65.0 °C at 760 mmHg

InChIKey: ZGYYPTJWJBEXBC-JZWIFLOVSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)F)N

IUPAC Name: (2S,3S,4R,5S)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol

InChI: InChI=1S/C10H12FN5O3/c11-5-7(18)4(1-17)19-10(5)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5+,7-,10-/m0/s1

Synonyms: L-2'-F-Ara-Adenosine; 9-(2-Deoxy-2-fluoro-beta-L-arabinofuranosyl)adenine; (2S,3S,4R,5S)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol; 9-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-9H-purin-6-amine; 9H-Purin-6-amine, 9-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-

9-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)guanine

Description: 9-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)guanine is a modified nucleoside where guanine is attached to a β-L-arabinofuranosyl sugar with a 2-deoxy-2-fluoro modification. This modification enhances the stability and alters the chemical properties of the nucleoside, making it useful in nucleic acid chemistry for applications such as nucleotide analog synthesis and structural studies.

CAT: BRP-01594

CAS: 193754-19-7

Molecular Formula: C10H12FN5O4

Molecular Weight: 285.23

Purity: ≥98%

Appearance: White to off-white powder

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Density: 2.17±0.1 g/cm3

Boiling Point: 726.1±70.0 °C at 760 mmHg

InChIKey: UXUZARPLRQRNNX-LSSUFRDISA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)F)N=C(NC2=O)N

IUPAC Name: 2-amino-9-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4+,6-,9-/m0/s1

Synonyms: L-2'-F-Ara-Guanosine; 9-(2-Fluoro-2-deoxy-β-L-arabinofuranosyl)guanine; 6H-Purin-6-one, 2-amino-9-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-3,9-dihydro-; 2-Amino-9-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-3,9-dihydro-6H-purin-6-one; 2-amino-9-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]purin-6-ol; 6H-Purin-6-one, 2-amino-9-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-1,9-dihydro-; 2-Amino-9-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one

1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)uracil

Description: 1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)uracil is a modified nucleoside where uracil is attached to a β-L-arabinofuranosyl sugar with a 2-deoxy-2-fluoro modification. This modification enhances the stability and alters the chemical properties of the nucleoside, making it useful in nucleic acid chemistry for applications such as nucleotide analog synthesis and structural studies.

CAT: BRP-01595

CAS: 1312300-54-1

Molecular Formula: C9H11FN2O5

Molecular Weight: 246.19

Purity: ≥98%

Appearance: White to off-white powder

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Density: 1.63±0.1 g/cm3

InChIKey: UIYWFOZZIZEEKJ-UCVXFZOQSA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)F

IUPAC Name: 1-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6+,7-,8-/m0/s1

Synonyms: 1-((2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-Deoxy-2'-fluoro-beta-L-arabinouridine; 1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-; 2'-Fluoro-5-ethyl-1-β-L-arabinofuranosyluracil

N,2'-O,3'-O-Triacetylcytidine

Description: N,2'-O,3'-O-Triacetylcytidine is an exceptional biomedical product, used for studying conspicuous viral infections, such as hepatitis C and influenza. It has the remarkable ability to impede viral RNA replication.

CAT: BRP-01628

CAS: 40632-06-2

Molecular Formula: C15H19N3O8

Molecular Weight: 369.33

Appearance: White to off-white powder

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Storage: Store at -20 °C

Density: 1.53±0.1 g/cm3

InChIKey: PWCGIZSEUGLASX-FMKGYKFTSA-N

CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)OC(=O)C)OC(=O)C

IUPAC Name: [(2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1-yl)-4-acetyloxy-2-(hydroxymethyl)oxolan-3-yl] acetate

InChI: InChI=1S/C15H19N3O8/c1-7(20)16-11-4-5-18(15(23)17-11)14-13(25-9(3)22)12(24-8(2)21)10(6-19)26-14/h4-5,10,12-14,19H,6H2,1-3H3,(H,16,17,20,23)/t10-,12-,13-,14-/m1/s1

Synonyms: N4-acetyl-2',3'-diacetyl-cytidine; 2',3'-diAc-C(Ac); Cytidine, N-acetyl-, 2',3'-diacetate; (2R,3R,4R,5R)-2-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl diacetate; N-Acetyl-2',3'-di-O-acetylcytidine

5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O,4'-C-methyleneguanosine

Description: 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O,4'-C-methyleneguanosine is a revolutionary biomedical substance renowned for its remarkable antiviral and antiproliferative attributes.

CAT: BRP-01629

CAS: 206055-72-3

Molecular Formula: C36H37N5O8

Molecular Weight: 667.71

Purity: ≥95%

Appearance: Off-white to yellow powder

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Storage: Store at -20 °C

Density: 1.41±0.1 g/cm3

InChIKey: JMGQUFRCVHVMAX-UBMDZZGASA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C4C(C(O3)(CO4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O

IUPAC Name: N-[9-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C36H37N5O8/c1-21(2)31(43)39-34-38-30-27(32(44)40-34)37-20-41(30)33-28-29(42)35(49-33,18-47-28)19-48-36(22-8-6-5-7-9-22,23-10-14-25(45-3)15-11-23)24-12-16-26(46-4)17-13-24/h5-17,20-21,28-29,33,42H,18-19H2,1-4H3,(H2,38,39,40,43,44)/t28-,29+,33-,35-/m1/s1

Synonyms: N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-guanosine; N2-iBu-DMT-2'-O-4'-C-Locked-Gr; N-(9-{(1R,3R,4R,7S)-1-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-7-hydroxy-2,5-dioxa-bicyclo[2.2.1]hept-3-yl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O,4'-C-methylene-N-(2-methyl-1-oxopropyl)-; (1R,3R,4R,7S)-1-(4,4'-Dimethoxytrityloxymethyl)-7-hydroxy-3-(2-N-isobutyrylguanin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane

N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-2'-O,4'-C-methylenecytidine

Description: N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-2'-O,4'-C-methylenecytidine, a highly potent compound extensively employed in the biomedical field, exhibits exceptional efficacy in combatting viral infections. This compound particularly exhibits remarkable proficiency against RNA viruses, such as SARS-CoV-2, ensuring its pervasive usefulness. By engaging viral RNA polymerase, it effectively impedes viral replication, thereby portraying its indispensable antiviral attributes.

CAT: BRP-01630

CAS: 445012-77-1

Molecular Formula: C39H37N3O8

Molecular Weight: 675.73

Purity: ≥98% by HPLC

Appearance: White, off-white to faint yellow powder

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Storage: Store at 2-8 °C, in tightly closed container, protected from light and humidity

Density: 1.32±0.1 g/cm3

InChIKey: CTGWFRQUULNNIN-OSZGUBSQSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C4C(C(O3)(CO4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O

IUPAC Name: N-(1-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide

InChI: InChI=1S/C39H37N3O8/c1-25-22-42(37(45)41-34(25)40-35(44)26-10-6-4-7-11-26)36-32-33(43)38(50-36,23-48-32)24-49-39(27-12-8-5-9-13-27,28-14-18-30(46-2)19-15-28)29-16-20-31(47-3)21-17-29/h4-22,32-33,36,43H,23-24H2,1-3H3,(H,40,41,44,45)/t32-,33+,36-,38-/m1/s1

Synonyms: N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-5-methyl-cytidine; N-(1-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide; Benzamide, N-[1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-α-L-lyxofuranosyl]-1,2-dihydro-5-methyl-2-oxo-4-pyrimidinyl]-; N-[1-[2,5-Anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-α-L-lyxofuranosyl]-1,2-dihydro-5-methyl-2-oxo-4-pyrimidinyl]benzamide; N4-Bz-DMT-2'-O-4'-C-Locked-5-Me-Cr

N4-Benzoyl-5'-O-(dimethoxytrityl)-5-methyl-2'-O-methylcytidine

Description: N4-Benzoyl-5'-O-(dimethoxytrityl)-5-methyl-2'-O-methylcytidine, a recently developed cytidine derivative, exhibits potential application in treating various diseases, such as cancer and viral infections, by suppressing malignancy and viral proliferation whilst preserving normal cells. With its unique mechanism, this product may have a significant impact in the combat of severe afflictions.

CAT: BRP-01631

CAS: 741725-57-5

Molecular Formula: C39H39N3O8

Molecular Weight: 677.76

Purity: ≥98% by HPLC

Appearance: White, off-white to faint yellow powder

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Storage: Store at 2-8 °C, Keep in a dark and dry place

Density: 1.26±0.1 g/cm3 (Predicted)

InChIKey: BUUDDUQHVVDKLA-TUDCZORBSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OC

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C39H39N3O8/c1-25-23-42(38(45)41-35(25)40-36(44)26-11-7-5-8-12-26)37-34(48-4)33(43)32(50-37)24-49-39(27-13-9-6-10-14-27,28-15-19-30(46-2)20-16-28)29-17-21-31(47-3)22-18-29/h5-23,32-34,37,43H,24H2,1-4H3,(H,40,41,44,45)/t32-,33-,34-,37-/m1/s1

Synonyms: N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyl-Cytidine; DMT-2'-O-Me-5-Me-C(Bz); 5'-O-DMT-2'-OMe-N4-Bz-5-Me-C; N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine; 5'-O-(4,4'-Dimethoxytrityl)-N4-Benzoyl-2'-O-Methy-5-MethyCytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-5-methyl-2'-O-methylcytidine; N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine

5'-O-DMT-2'-O-methylcytidine

Description: 5'-O-DMT-2'-O-methylcytidine is a biomedicine research product used for the treatment of viral infections, cancer, and neurological disorders. It acts as an antiviral and anticancer agent by inhibiting viral replication and tumor growth, respectively. Additionally, it also has neuroprotective properties that help in treating neurological disorders.

CAT: BRP-01632

CAS: 103285-21-8

Molecular Formula: C31H33N3O7

Molecular Weight: 559.62

Purity: ≥98% by HPLC

Appearance: White to Off-white Powder

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Storage: Store at 2-8°C

Density: 1.3±0.1 g/cm3

Boiling Point: 729.7±70.0°C at 760 mmHg

InChIKey: JUECLTUXFCGWTO-YXINZVNLSA-N

CanonicalSMILES: COC1C(C(OC1N2C=CC(=NC2=O)N)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C31H33N3O7/c1-37-23-13-9-21(10-14-23)31(20-7-5-4-6-8-20,22-11-15-24(38-2)16-12-22)40-19-25-27(35)28(39-3)29(41-25)34-18-17-26(32)33-30(34)36/h4-18,25,27-29,35H,19H2,1-3H3,(H2,32,33,36)/t25-,27-,28-,29-/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine; DMT-2'-OMe-Cr; 5'-O-DMT-2'-O-methyl-D-cytidine; 5'-O-DMT-2'-OMe-rC; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylcytidine

5'-O-(Dimethoxytrityl)-2'-O-methylinosine

Description: 5'-O-(Dimethoxytrityl)-2'-O-methylinosine is an indispensable compound employed in the biomedical industry, showcasing considerable promise as a research tool for diverse afflictions and maladies. With profound implications in drug development, it enables the precise modulation of molecular pathways and gene expressions. The multifaceted utilization of this compound extends to the realm of research of cancer, viral infections and neurological impairments.

CAT: BRP-01633

CAS: 128219-84-1

Molecular Formula: C32H32N4O7

Molecular Weight: 584.63

Purity: ≥97% by HPLC

Appearance: White to off-white powder

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Storage: Store at 2-8 °C, Keep in a dark and dry place

Density: 1.35±0.1 g/cm3

Boiling Point: 841.8±65.0 °C at 760 mmHg

InChIKey: KXFBGUCGEWPHRA-QWOIFIOOSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=CNC3=O)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: 9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C32H32N4O7/c1-39-23-13-9-21(10-14-23)32(20-7-5-4-6-8-20,22-11-15-24(40-2)16-12-22)42-17-25-27(37)28(41-3)31(43-25)36-19-35-26-29(36)33-18-34-30(26)38/h4-16,18-19,25,27-28,31,37H,17H2,1-3H3,(H,33,34,38)/t25-,27-,28-,31-/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-inosine; DMT-2'-OMe-Ir; 5'-O-Dmt-2'-O-methyl-inosine; Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-; 9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one

5'-O-DMT-2'-O-methylguanosine

Description: 5'-O-DMT-2'-O-methylguanosine, a nucleoside analogue, finds its purpose in biomedical research due to its potential antiviral activity against RNA viruses, an area of significant scientific interest. Its inhibitory role in the replication of notorious viruses such as Zika virus and hepatitis C virus warrants further academic study.

CAT: BRP-01634

CAS: 103285-24-1

Molecular Formula: C32H33N5O7

Molecular Weight: 599.65

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Density: 1.40±0.1 g/cm3

InChIKey: AYVWAUNZRMANQB-BQOYKFDPSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C32H33N5O7/c1-40-22-13-9-20(10-14-22)32(19-7-5-4-6-8-19,21-11-15-23(41-2)16-12-21)43-17-24-26(38)27(42-3)30(44-24)37-18-34-25-28(37)35-31(33)36-29(25)39/h4-16,18,24,26-27,30,38H,17H2,1-3H3,(H3,33,35,36,39)/t24-,26-,27-,30-/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-guanosine; DMT-2'-OMe-Gr; 2'-O-Methyl-5'-O-DMT-D-guanosine; 5'-O-Dimethoxytrityl-2'-O-methylguanosine; 5'-O-DMT-2'-O-methyl-D-guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylguanosine

3'-O-Acetyl-5'-O-DMT-5-iodo-2'-O-methyl-uridine

Description: Highly specialized in the field of biomedicine, 3'-O-Acetyl-5'-O-DMT-5-iodo-2'-O-methyl-uridine stands as a critical compound. Its employment primarily revolves around synthesizing nucleotide analogs for antiviral drug development and acting as a probe in biochemical studies concerning RNA. Promising therapeutic applications against viral infections, like HIV and hepatitis B, are attributed to this product.

CAT: BRP-01635

CAS: 1374692-34-8

Molecular Formula: C33H33IN2O9

Molecular Weight: 728.53

Purity: ≥95%

Appearance: White Solid

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Density: 1.55±0.1 g/cm3

InChIKey: FRHDXHYTYBOQIT-BUVRPPHQSA-N

CanonicalSMILES: CC(=O)OC1C(OC(C1OC)N2C=C(C(=O)NC2=O)I)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: [(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(5-iodo-2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl] acetate

InChI: InChI=1S/C33H33IN2O9/c1-20(37)44-28-27(45-31(29(28)42-4)36-18-26(34)30(38)35-32(36)39)19-43-33(21-8-6-5-7-9-21,22-10-14-24(40-2)15-11-22)23-12-16-25(41-3)17-13-23/h5-18,27-29,31H,19H2,1-4H3,(H,35,38,39)/t27-,28-,29-,31-/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-3'-acetyl-5-Iodo-2'-O-methyl-uridine; 5'-O-DMT-3'-Ac-5-I-2'-OMe-Ur; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-3'-O-acetyl-5-iodouridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-iodo-2'-O-methyl-uridine 3'-acetate; 5-Iodo-5'-DMT-2'-O-methyl-3'-acetyl-uridine; 3'-O-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-5-iodo-2'-O-methyluridine

5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine

Description: 5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is an advanced compound prescribed for research of viral infections, demonstrating inhibitory efficacy by selectively targeting specific RNA viruses. Employing a potent mechanism of inhibiting viral replication and considerably attenuating viral loads, this compound exhibits promising potential in the research of RNA virus-induced ailments such as influenza and hepatitis C.

CAT: BRP-01636

CAS: 171486-53-6

Molecular Formula: C38H39N5O8

Molecular Weight: 693.74

Purity: ≥95%

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Density: 1.31±0.1 g/cm3

InChIKey: ZTBYTNLGRCUAEU-BEGXHNNXSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OCC#C

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-prop-2-ynoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C38H39N5O8/c1-6-20-49-32-31(44)29(51-36(32)43-22-39-30-33(43)40-37(42-35(30)46)41-34(45)23(2)3)21-50-38(24-10-8-7-9-11-24,25-12-16-27(47-4)17-13-25)26-14-18-28(48-5)19-15-26/h1,7-19,22-23,29,31-32,36,44H,20-21H2,2-5H3,(H2,40,41,42,45,46)/t29-,31-,32-,36-/m1/s1

Synonyms: N2-iBu-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-2-propyn-1-yl-Guanosine; N2-iBu-DMT-2'-O-propargyl-Gr; N2-iso-Butyroyl-5'-(4,4'-dimethoxytrityl)-2'-O-propargylguanosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-N-isobutyryl-2'-O-2-propyn-1-ylguanosine; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-2-propynyl-

5'-O-DMT-2'-O-Propargyl-Uridine

Description: 5'-O-DMT-2'-O-Propargyl-Uridine, a nucleoside analog commonly used for cancer therapy, serves as a potent inhibitor of nucleic acid synthesis, thus holding the capacity to trigger cell death upon incorporation with DNA of cancerous cells. Such an enticing compound is marked with potential therapeutic benefits for patients suffering from leukemia and lymphoma, thereby marking a boon for the medical fraternity in tackling cancer at its core.

CAT: BRP-01637

CAS: 171486-54-7

Molecular Formula: C33H32N2O8

Molecular Weight: 584.63

Purity: ≥97% by HPLC

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Density: 1.35±0.1 g/cm3

InChIKey: VFYMBSPPKISNAZ-PMFUCWTESA-N

CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=O)NC5=O)OCC#C)O

IUPAC Name: 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

InChI: InChI=1S/C33H32N2O8/c1-4-20-41-30-29(37)27(43-31(30)35-19-18-28(36)34-32(35)38)21-42-33(22-8-6-5-7-9-22,23-10-14-25(39-2)15-11-23)24-12-16-26(40-3)17-13-24/h1,5-19,27,29-31,37H,20-21H2,2-3H3,(H,34,36,38)/t27-,29-,30-,31-/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-uridine; 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; DMT-2'-O-propargyl-Ur; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propyn-1-yl-; 5-O-(4,4'-dimethoxytrityl)-1-deoxy-2-O-prop-2-ynyl-1-uracil-1-yl-beta-D-ribo-pentofuranose; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propyn-1-yluridine

N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine

Description: N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine stands as an influential and efficacious compound widely employed in the research of ailments, encompassing cancers and viral infections.

CAT: BRP-01638

CAS: 171486-51-4

Molecular Formula: C41H37N5O7

Molecular Weight: 711.76

Purity: ≥95%

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Density: 1.29±0.1 g/cm3

InChIKey: HJXHRBGNFZRNDJ-MUMPVVMASA-N

CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)OCC#C)O

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-prop-2-ynoxyoxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C41H37N5O7/c1-4-23-51-36-35(47)33(53-40(36)46-26-44-34-37(42-25-43-38(34)46)45-39(48)27-11-7-5-8-12-27)24-52-41(28-13-9-6-10-14-28,29-15-19-31(49-2)20-16-29)30-17-21-32(50-3)22-18-30/h1,5-22,25-26,33,35-36,40,47H,23-24H2,2-3H3,(H,42,43,45,48)/t33-,35-,36-,40-/m1/s1

Synonyms: N6-Bz-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-adenosine; N6-Bz-DMT-2'-O-propargyl-Ar; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(propyn-1-yl)adenosine; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl adenosine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-2-propyn-1-yladenosine; N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

5'-O-DMT-cytidine

Description: 5'-O-DMT-cytidine is a highly influential and extensively utilized component, having extraordinary aptitude as a remarkable countermeasure against both DNA and RNA viral compounds. Profoundly indispensable in the confrontment of pernicious viral afflictions, such as herpes simplex, HIV and hepatitis, this exalted compound exhibits an unparalleled capability in suppressing viral replication.

CAT: BRP-01639

CAS: 112897-99-1

Molecular Formula: C30H31N3O7

Molecular Weight: 545.58

Purity: ≥95%

Appearance: Powder

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Density: 1.34 g/cm3

Boiling Point: 742.5±70.0°C at 760 mmHg

InChIKey: SUENBDLQORXVMC-YULOIDQLSA-N

CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=NC5=O)N)O)O

IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3,4-dihydroxyoxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C30H31N3O7/c1-37-22-12-8-20(9-13-22)30(19-6-4-3-5-7-19,21-10-14-23(38-2)15-11-21)39-18-24-26(34)27(35)28(40-24)33-17-16-25(31)32-29(33)36/h3-17,24,26-28,34-35H,18H2,1-2H3,(H2,31,32,36)/t24-,26-,27-,28-/m1/s1

Synonyms: 5'-O-(4,4'-Dimethoxytrityl)cytidine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]cytidine; 4-Amino-1-((2R,3R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidin-2(1H)-one; DMT-Cr

5-Iodo-2'-O-methylcytidine

Description: 5-Iodo-2'-O-methylcytidine, a nucleoside analogue (NSA), is a chemotherapeutic agent that induces neuronal differentiation.

CAT: BRP-01640

CAS: 847650-69-5

Molecular Formula: C10H14IN3O5

Molecular Weight: 383.14

Purity: ≥95%

Appearance: White to off-white powder

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Storage: Store at 2-8 °C, Keep in a dark and dry place

Density: 2.24±0.1 g/cm3

Boiling Point: 533.0±60.0°C at 760 mmHg

InChIKey: JQWRBXTVVLSBBM-JXOAFFINSA-N

CanonicalSMILES: COC1C(C(OC1N2C=C(C(=NC2=O)N)I)CO)O

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-5-iodopyrimidin-2-one

InChI: InChI=1S/C10H14IN3O5/c1-18-7-6(16)5(3-15)19-9(7)14-2-4(11)8(12)13-10(14)17/h2,5-7,9,15-16H,3H2,1H3,(H2,12,13,17)/t5-,6-,7-,9-/m1/s1

Synonyms: 5-Iodo-2'-O-methyl-cytidine; 5-I-2'-O-Me-Cr; Cytidine, 5-iodo-2'-O-methyl-; 4-Amino-1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one

3'-O-Propargylguanosine

Description: 3'-O-Propargylguanosine, a widely utilized biomedicine product, has gained significant attention as a valuable tool in academic research for exploring diverse cellular processes. Serving as a modified guanosine nucleotide, it exhibits the ability to be seamlessly integrated into RNA molecules during the transcriptional phase. By leveraging this product, researchers can delve deep into the intricate realm of RNA biology, meticulously examining its structural composition, synthetic mechanisms, and functional aspects.

CAT: BRP-01641

CAS: 1429494-08-5

Molecular Formula: C13H15N5O5

Molecular Weight: 321.29

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Density: 1.76±0.1 g/cm3

Boiling Point: 737.5±70.0 °C at 760 mmHg

InChIKey: XJXNRNJCUMEGAU-WOUKDFQISA-N

CanonicalSMILES: C#CCOC1C(OC(C1O)N2C=NC3=C2N=C(NC3=O)N)CO

IUPAC Name: 2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-prop-2-ynoxyoxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C13H15N5O5/c1-2-3-22-9-6(4-19)23-12(8(9)20)18-5-15-7-10(18)16-13(14)17-11(7)21/h1,5-6,8-9,12,19-20H,3-4H2,(H3,14,16,17,21)/t6-,8-,9-,12-/m1/s1

Synonyms: 3'-O-propargyl-guanosine; 2-amino-9-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one; 3'-O-2-Propyn-1-ylguanosine; 3'-Propargylguanosine; 3'-O-propargyl-Gr; 3'-O-Propargyl-D-guanosine; 3'-(O-propargyl) Guanosine

2-Amino-2'-O-(2-propyn-1-yl)adenosine

Description: 2-Amino-2'-O-(2-propyn-1-yl)adenosine is an adenosine receptor agonist capable of orchestrating and redefining the intricate web of cellular signaling pathways.

CAT: BRP-01642

CAS: 1451256-04-4

Molecular Formula: C13H16N6O4

Molecular Weight: 320.30

Purity: ≥95%

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Density: 1.8±0.1 g/cm3

Boiling Point: 757.8±70.0°C at 760 mmHg

InChIKey: AGYDCNMIAHDTSH-WOUKDFQISA-N

CanonicalSMILES: C#CCOC1C(C(OC1N2C=NC3=C(N=C(N=C32)N)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(2,6-diaminopurin-9-yl)-2-(hydroxymethyl)-4-prop-2-ynoxyoxolan-3-ol

InChI: InChI=1S/C13H16N6O4/c1-2-3-22-9-8(21)6(4-20)23-12(9)19-5-16-7-10(14)17-13(15)18-11(7)19/h1,5-6,8-9,12,20-21H,3-4H2,(H4,14,15,17,18)/t6-,8-,9-,12-/m1/s1

Synonyms: 2'-O-propargyl-2-amino-adenosine; 2'-O-propargyl-2-amino-Ar; 2'-O-Propygyl-2-aminoadenosine; Adenosine, 2-amino-2'-O-2-propyn-1-yl-; 9-(2-O-Propargyl-beta-D-ribofuranosyl)-9H-purine-2,6-diamine; (2R,3R,4R,5R)-5-(2,6-Diamino-9H-purin-9-yl)-2-(hydroxymethyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-ol; 2-Amino-2'-O-2-propyn-1-yladenosine

5'-Deoxy-5'-fluorouridine

Description: 5'-Deoxy-5'-fluorouridine is a modified nucleoside lacking the 5'-hydroxyl group of uridine and substituted with a fluorine atom. This compound is utilized in biochemical and pharmaceutical research as an antiviral and anticancer agent. It can be incorporated into RNA during transcription, altering RNA structure and function. Studying its effects helps understand RNA biology and explore potential therapeutic applications.

CAT: BRP-01643

CAS: 38817-29-7

Molecular Formula: C9H11FN2O5

Molecular Weight: 246.19

Purity: 95%

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Density: 1.601±0.06 g/cm3

Melting Point: 141-142 °C

InChIKey: JIWIXZJAAUQOCE-XVFCMESISA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CF)O)O

IUPAC Name: 1-[(2R,3R,4S,5S)-5-(fluoromethyl)-3,4-dihydroxyoxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H11FN2O5/c10-3-4-6(14)7(15)8(17-4)12-2-1-5(13)11-9(12)16/h1-2,4,6-8,14-15H,3H2,(H,11,13,16)/t4-,6-,7-,8-/m1/s1

Synonyms: 5'-fluoro-uridine; 5'-F-Ur; 1-((2R,3R,4S,5S)-5-(fluoromethyl)-3,4-dihydroxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-DFUR; 5'-Deoxy-5-fluorouridine; 5'-Fluorodeoxyuridine; NSC 524310

3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine

Description: 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine is a vital compound used in the biomedical industry. It acts as a crucial building block in the synthesis of RNA and DNA molecules, playing a significant role in gene expression and regulation. This compound finds utility in research related to nucleic acids, drug discovery, and the development of treatments targeting diseases such as cancer and viral infections.

CAT: BRP-01677

CAS: 69304-44-5

Molecular Formula: C22H39N5O6Si2

Molecular Weight: 525.76

Purity: ≥98%

Appearance: White to off-white crystalline powder

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Density: 1.36±0.1 g/cm3

Melting Point: >260 °C

InChIKey: CWVNMKRKFJYCCC-QTQZEZTPSA-N

CanonicalSMILES: CC(C)[Si]1(OCC2C(C(C(O2)N3C=NC4=C3N=C(NC4=O)N)O)O[Si](O1)(C(C)C)C(C)C)C(C)C

IUPAC Name: 9-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-amino-1H-purin-6-one

InChI: InChI=1S/C22H39N5O6Si2/c1-11(2)34(12(3)4)30-9-15-18(32-35(33-34,13(5)6)14(7)8)17(28)21(31-15)27-10-24-16-19(27)25-22(23)26-20(16)29/h10-15,17-18,21,28H,9H2,1-8H3,(H3,23,25,26,29)/t15-,17-,18-,21-/m1/s1

Synonyms: 3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-guanosine; 3',5'-TIPDS-Gr; 3',5'-O-TIPPS-guanosine; 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disoloxanediyl-D-guanosine; 3',5'-O-[1,1,3,3-Tetrakis(1-methylethyl)-1,3-disiloxanediyl]guanosine; 3',5'-TIPS-guanosine