What are nucleosides used for?

Nucleosides are base molecules used as starting materials for synthesizing nucleotides and phosphoramidites.

What is the difference between nucleosides and nucleotides?

Nucleosides lack phosphate groups, while nucleotides contain one or more phosphates required for enzymatic reactions.

Are nucleosides used directly in enzymatic reactions?

Nucleosides are typically chemically modified before being used in enzymatic workflows.

Can nucleosides be chemically modified?

Yes, modified nucleosides are widely used to introduce structural or functional changes in nucleic acids.

Why is nucleoside purity important?

High purity ensures correct downstream synthesis of nucleotides and phosphoramidites with predictable performance.

Nucleosides - RNA / BOC Sciences

N2-Ac-DMT-2'-OMe-Gr

Description: N2-Ac-DMT-2'-OMe-Gr is a modified nucleoside used in oligonucleotide synthesis. It consists of an acetyl (Ac) group attached to the N2 position of guanine, a dimethoxytrityl (DMT) protecting group, a methyl (Me) group at the 2' position of ribose, and a modified guanine (Gr). It is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enhancing stability or enabling interactions with complementary sequences.

CAT: BRP-01002

CAS: 909033-39-2

Molecular Formula: C34H35N5O8

Molecular Weight: 641.67

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Density: 1.38±0.1 g/cm3

InChIKey: IJLYUZAEWUUOCY-DWCTZGTLSA-N

CanonicalSMILES: O=C1N=C(NC(=O)C)NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(O)C3OC

IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide

InChI: InChI=1S/C34H35N5O8/c1-20(40)36-33-37-30-27(31(42)38-33)35-19-39(30)32-29(45-4)28(41)26(47-32)18-46-34(21-8-6-5-7-9-21,22-10-14-24(43-2)15-11-22)23-12-16-25(44-3)17-13-23/h5-17,19,26,28-29,32,41H,18H2,1-4H3,(H2,36,37,38,40,42)/t26-,28-,29-,32-/m1/s1

Synonyms: N2-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-guanosine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylguanosine

N4-dmf-DMT-2'-O-Me-5-Me-Cr

Description: N4-dmf-DMT-2'-O-Me-5-Me-Cr is a modified nucleoside used in oligonucleotide synthesis. It consists of a dibutylformamidine (dmf) group attached to the N4 position of cytosine, a dimethoxytrityl (DMT) protecting group, a methyl (Me) group at the 2' position of ribose, and methyl groups (Me) at the 5th position of cytosine. It is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enhancing stability or enabling interactions with complementary sequences.

CAT: BRP-01003

Molecular Formula: C35H40N4O7

Molecular Weight: 628.71

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InChIKey: BEDTXIPBGSIHIU-WTGZKXAYSA-N

CanonicalSMILES: O=C1N=C(N=CN(C)C)C(=CN1C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(O)C2OC)C

IUPAC Name: N'-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)-N,N-dimethylformimidamide

InChI: InChI=1S/C35H40N4O7/c1-23-20-39(34(41)37-32(23)36-22-38(2)3)33-31(44-6)30(40)29(46-33)21-45-35(24-10-8-7-9-11-24,25-12-16-27(42-4)17-13-25)26-14-18-28(43-5)19-15-26/h7-20,22,29-31,33,40H,21H2,1-6H3/t29-,30-,31-,33-/m1/s1

Synonyms: N4-dimethylformamidine-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyl-cytidine

Related CAS: 2940857-82-7 (Z-isomer)

N4-Ac-DMT-2'-O-propargyl-Cr

Description: N4-Ac-DMT-2'-O-propargyl-Cr is a modified nucleoside used in oligonucleotide synthesis. It consists of an acetyl (Ac) group attached to the N4 position of cytosine, a dimethoxytrityl (DMT) protecting group, and a propargyl group attached to the 2' position of ribose, along with a modified cytosine (Cr). It is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, which can be useful for various applications in molecular biology and biotechnology.

CAT: BRP-01004

CAS: 1498305-50-2

Molecular Formula: C35H35N3O8

Molecular Weight: 625.67

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Density: 1.25±0.1 g/cm3

InChIKey: WTXRMORXMCBUCK-WXQJYUTRSA-N

CanonicalSMILES: O=C1N=C(C=CN1C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(O)C2OCC#C)NC(=O)C

IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

InChI: InChI=1S/C35H35N3O8/c1-5-21-44-32-31(40)29(46-33(32)38-20-19-30(36-23(2)39)37-34(38)41)22-45-35(24-9-7-6-8-10-24,25-11-15-27(42-3)16-12-25)26-13-17-28(43-4)18-14-26/h1,6-20,29,31-33,40H,21-22H2,2-4H3,(H,36,37,39,41)/t29-,31-,32-,33-/m1/s1

Synonyms: N4-Ac-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-cytidine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propyn-1-ylcytidine

N2-Ac-DMT-2'-O-propargyl-Gr

Description: N2-Ac-DMT-2'-O-propargyl-Gr is a modified nucleoside used in oligonucleotide synthesis. It consists of an acetyl (Ac) group attached to the N2 position of guanine, a dimethoxytrityl (DMT) protecting group, and a propargyl group attached to the 2' position of ribose, along with a modified guanine (Gr). The modification is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enabling various applications in molecular biology and biotechnology.

CAT: BRP-01005

Molecular Formula: C36H35N5O8

Molecular Weight: 665.70

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InChIKey: CEGYIJROMOEVDV-UTBAFCPYSA-N

IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide

InChI: InChI=1S/C36H35N5O8/c1-5-19-47-31-30(43)28(49-34(31)41-21-37-29-32(41)39-35(38-22(2)42)40-33(29)44)20-48-36(23-9-7-6-8-10-23,24-11-15-26(45-3)16-12-24)25-13-17-27(46-4)18-14-25/h1,6-18,21,28,30-31,34,43H,19-20H2,2-4H3,(H2,38,39,40,42,44)/t28-,30-,31-,34-/m1/s1

Synonyms: N2-Ac-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-guanosine

3',5'-O-diDMT-2'-O-propargyl-Ur

Description: 3',5'-O-diDMT-2'-O-propargyl-Ur is a modified nucleoside used in oligonucleotide synthesis. It consists of two dimethoxytrityl (DMT) protecting groups attached to the 3' and 5' hydroxyl groups of uracil, and a propargyl group attached to the 2' position of ribose. The modification is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enabling various applications in molecular biology and biotechnology.

CAT: BRP-01006

Molecular Formula: C54H50N2O10

Molecular Weight: 887.00

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InChIKey: FHAVBSPASFBLTH-BUBCVBHASA-N

IUPAC Name: 1-((2R,3R,4R,5R)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

InChI: InChI=1S/C54H50N2O10/c1-6-35-63-50-49(66-54(38-15-11-8-12-16-38,41-21-29-45(61-4)30-22-41)42-23-31-46(62-5)32-24-42)47(65-51(50)56-34-33-48(57)55-52(56)58)36-64-53(37-13-9-7-10-14-37,39-17-25-43(59-2)26-18-39)40-19-27-44(60-3)28-20-40/h1,7-34,47,49-51H,35-36H2,2-5H3,(H,55,57,58)/t47-,49-,50-,51-/m1/s1

Synonyms: 3',5'-O-di(4,4'-dimethoxytrityl)-2'-O-propargyl-uridine

5'-O-DMTr-2'-O-TBDMS-G(Ac)

Description: 5'-O-DMTr-2'-O-TBDMS-G(Ac) is a modified nucleoside used in oligonucleotide synthesis. It consists of a dimethoxytrityl (DMTr) protecting group at the 5' hydroxyl, a tert-butyldimethylsilyl (TBDMS) group at the 2' position of ribose, and an acetyl (Ac) group attached to guanine. This modification is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enabling various applications in molecular biology and biotechnology.

CAT: BRP-01007

CAS: 1256468-15-1

Molecular Formula: C39H47N5O8Si

Molecular Weight: 741.92

Purity: ≥98% by HPLC

Appearance: White, off-white to faint yellow powder

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Storage: Store at 2-8 °C

Density: 1.26±0.1 g/cm3

InChIKey: WMJSMYRPSADDEA-QGGAYTEESA-N

CanonicalSMILES: O=C1N=C(NC(=O)C)NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(O)C3O[Si](C)(C)C(C)(C)C

IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide

InChI: InChI=1S/C39H47N5O8Si/c1-24(45)41-37-42-34-31(35(47)43-37)40-23-44(34)36-33(52-53(7,8)38(2,3)4)32(46)30(51-36)22-50-39(25-12-10-9-11-13-25,26-14-18-28(48-5)19-15-26)27-16-20-29(49-6)21-17-27/h9-21,23,30,32-33,36,46H,22H2,1-8H3,(H2,41,42,43,45,47)/t30-,32-,33-,36-/m1/s1

Synonyms: N2-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-guanine; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]guanosine; 5'-O-DMT-2'-O-TBDMS-N2-Acetyl-Guanosine

5-Acrylic-5'-DMT-dU

Description: 5-Acrylic-5'-DMT-dU features an acrylic group attached to the 5 position of deoxyuridine, along with a dimethoxytrityl (DMT) protecting group. It is used in oligonucleotide synthesis to introduce specific functionalities, such as for covalent modification or interaction with other biomolecules.

CAT: BRP-01008

CAS: 923023-62-5

Molecular Formula: C33H32N2O9

Molecular Weight: 600.62

Purity: ≥98% by HPLC

Appearance: White, off-white to yellow powder

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Storage: Store at 2-8 °C

Density: 1.369±0.06 g/cm3

InChIKey: GRDHCWWOTJFHSF-CTJHEALJSA-N

CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(CC(O4)N5C=C(C(=O)NC5=O)C=CC(=O)O)O

IUPAC Name: (E)-3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoic acid

InChI: InChI=1S/C33H32N2O9/c1-41-25-13-9-23(10-14-25)33(22-6-4-3-5-7-22,24-11-15-26(42-2)16-12-24)43-20-28-27(36)18-29(44-28)35-19-21(8-17-30(37)38)31(39)34-32(35)40/h3-17,19,27-29,36H,18,20H2,1-2H3,(H,37,38)(H,34,39,40)/b17-8+/t27-,28+,29+/m0/s1

Synonyms: 5-Acrylic-5'-O-(4,4'-dimethoxytrityl)-uridine; (E)-3-(1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylic acid; (2E)-3-[1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-2-propenoic acid; (E)-5-(2-Carboxyvinyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine

5-Acrylic-5'-DMT-dU TEA salt

Description: 5-Acrylic-5'-DMT-dU TEA salt is the triethylammonium (TEA) salt form of 5-Acrylic-5'-DMT-dU, typically used to provide better solubility or handling during synthesis.

CAT: BRP-01009

Molecular Formula: C33H32N2O9.C6H15N

Molecular Weight: 701.82

Purity: ≥98% by HPLC

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Storage: Store at 2-8 °C

InChIKey: SKPFWOYCDYVDPX-IZFLFKNXSA-N

CanonicalSMILES: CCN(CC)CC.COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(CC(O4)N5C=C(C(=O)NC5=O)C=CC(=O)O)O

IUPAC Name: (E)-3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoic acid;N,N-diethylethanamine

InChI: InChI=1S/C33H32N2O9.C6H15N/c1-41-25-13-9-23(10-14-25)33(22-6-4-3-5-7-22,24-11-15-26(42-2)16-12-24)43-20-28-27(36)18-29(44-28)35-19-21(8-17-30(37)38)31(39)34-32(35)40;1-4-7(5-2)6-3/h3-17,19,27-29,36H,18,20H2,1-2H3,(H,37,38)(H,34,39,40);4-6H2,1-3H3/b17-8+;/t27-,28+,29+;/m0./s1

Synonyms: (E)-5-(2-Carboxyvinyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine, triethylamine salt; 5-Acrylic-5'-O-(4,4'-dimethoxytrityl)-uridine,triethylamine salt; (E)-3-(1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylic acid triethylamine salt; (2E)-3-[1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-2-propenoic acid triethylamine salt

Related CAS: 923023-62-5 (free base)

3',5'-di-O-TBDMS-2'-O-4'-C-Locked-Gr

Description: 3',5'-di-O-TBDMS-2'-O-4'-C-Locked-Gr consists of two tert-butyldimethylsilyl (TBDMS) protecting groups attached to the 3' and 5' hydroxyl groups, along with a 2'-O modificationa, 4'-carbon locked guanine (Locked-Gr). It is used in oligonucleotide synthesis to enhance sequence stability and specific biological activities.

CAT: BRP-01010

CAS: 2940861-48-1

Molecular Formula: C23H41N5O5Si2

Molecular Weight: 523.77

Purity: ≥98% by HPLC

Appearance: White, off-white to faint yellow powder

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Storage: Store at RT. Keep container tightly closed. Protect from light.

Density: 1.24±0.1 g/cm3

Boiling Point: 616.6±65.0 °C at 760 mmHg

InChIKey: LDLRSVCCRZMOLN-QIEVIBBNSA-N

CanonicalSMILES: O=C1N=C(N)NC2=C1N=CN2C3OC4(COC3C4O[Si](C)(C)C(C)(C)C)CO[Si](C)(C)C(C)(C)C

IUPAC Name: 2-amino-9-((1R,3R,4R,7S)-7-((tert-butyldimethylsilyl)oxy)-1-(((tert-butyldimethylsilyl)oxy)methyl)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-1,9-dihydro-6H-purin-6-one

InChI: InChI=1S/C23H41N5O5Si2/c1-21(2,3)34(7,8)31-12-23-11-30-15(16(23)33-35(9,10)22(4,5)6)19(32-23)28-13-25-14-17(28)26-20(24)27-18(14)29/h13,15-16,19H,11-12H2,1-10H3,(H3,24,26,27,29)/t15-,16+,19-,23-/m1/s1

Synonyms: 3',5'-di-O-(t-butyl-dimethylsilyl)-2'-O-4'-C-Locked-guanosine

5'-O-Ts-3'-O-TBDMS-2'-O-4'-C-Locked-Ur

Description: 5'-O-Ts-3'-O-TBDMS-2'-O-4'-C-Locked-Ur features a p-toluenesulfonyl (Ts) group attached to the 5' hydroxyl, a tert-butyldimethylsilyl (TBDMS) group attached to the 3' hydroxyl, and a 2'-O modificationa, a 4'-carbon locked uracil (Locked-Ur). It is used in oligonucleotide synthesis to introduce specific protecting groups or functional moieties.

CAT: BRP-01011

CAS: 2387667-44-7

Molecular Formula: C23H32N2O8SSi

Molecular Weight: 524.66

Purity: ≥98% by HPLC

Appearance: White, off-white to faint yellow powder

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Storage: Store at 2-8 °C

Density: 1.33±0.1 g/cm3

InChIKey: YXMSGMAYACMFID-VLVHOKLOSA-N

CanonicalSMILES: O=C1C=CN(C(=O)N1)C2OC3(COC2C3O[Si](C)(C)C(C)(C)C)COS(=O)(=O)C4=CC=C(C=C4)C

IUPAC Name: ((1R,3R,4R,7S)-7-((tert-butyldimethylsilyl)oxy)-3-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl)methyl 4-methylbenzenesulfonate

InChI: InChI=1S/C23H32N2O8SSi/c1-15-7-9-16(10-8-15)34(28,29)31-14-23-13-30-18(19(23)33-35(5,6)22(2,3)4)20(32-23)25-12-11-17(26)24-21(25)27/h7-12,18-20H,13-14H2,1-6H3,(H,24,26,27)/t18-,19+,20-,23-/m1/s1

Synonyms: 5'-O-Tosyl-3'-O-(t-butyldimethylsilyl)-1-(2'-O,4'-C-methylene-beta-D-ribofuranosyl)-uridineacil; 5'-O-Ts-3'-O-TBDMS-LNA-Ur

5'-NH2-3'-O-TBDMS-2'-O-4'-C-Locked-Ur

Description: 5'-NH2-3'-O-TBDMS-2'-O-4'-C-Locked-Ur includes an amino (NH2) group replaced to the 5' hydroxyl, a tert-butyldimethylsilyl (TBDMS) group attached to the 3' hydroxyl, and a 2'-O modificationa, a 4'-carbon locked uracil (Locked-Ur). It is used in oligonucleotide synthesis to introduce amino functional groups.

CAT: BRP-01012

Molecular Formula: C16H27N3O5Si

Molecular Weight: 369.49

Purity: ≥98% by HPLC

Appearance: White, off-white to faint yellow powder

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Storage: Store at 2-8 °C

InChIKey: QJDAOGPSEQMRJU-IATRGZMQSA-N

IUPAC Name: 1-((1S,3R,4R,7S)-1-(aminomethyl)-7-((tert-butyldimethylsilyl)oxy)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidine-2,4(1H,3H)-dione

InChI: InChI=1S/C16H27N3O5Si/c1-15(2,3)25(4,5)24-12-11-13(23-16(12,8-17)9-22-11)19-7-6-10(20)18-14(19)21/h6-7,11-13H,8-9,17H2,1-5H3,(H,18,20,21)/t11-,12+,13-,16+/m1/s1

Synonyms: 5'-amino-3'-O-(t-butyldimethylsilyl)-1-(2'-O,4'-C-methylene-beta-D-ribofuranosyl)-uridineacil; 5'-NH2-3'-O-TBDMS-LNA-Ur

5'-N3-3'-O-TBDMS-2'-O-4'-C-Locked-Ur

Description: 5'-N3-3'-O-TBDMS-2'-O-4'-C-Locked-Ur consists of an N3 replaced to the 5' hydroxyl, a tert-butyldimethylsilyl (TBDMS) group attached to the 3' hydroxyl, and a 2'-O modificationa, a 4'-carbon locked uracil (Locked-Ur). It is used in oligonucleotide synthesis to introduce specific functional groups.

CAT: BRP-01013

Molecular Formula: C16H25N5O5Si

Molecular Weight: 395.49

Purity: ≥98% by HPLC

Appearance: White, off-white to faint yellow powder

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Storage: Store at 2-8 °C

InChIKey: YVKIMFHCMXNURY-IATRGZMQSA-N

IUPAC Name: 1-((1S,3R,4R,7S)-1-(azidomethyl)-7-((tert-butyldimethylsilyl)oxy)-2,5-dioxabicyclo[2.2.1]heptan-3-yl)pyrimidine-2,4(1H,3H)-dione

InChI: InChI=1S/C16H25N5O5Si/c1-15(2,3)27(4,5)26-12-11-13(21-7-6-10(22)19-14(21)23)25-16(12,9-24-11)8-18-20-17/h6-7,11-13H,8-9H2,1-5H3,(H,19,22,23)/t11-,12+,13-,16+/m1/s1

Synonyms: 5'-Azido-3'-O-(t-butyldimethylsilyl)-1-(2'-O,4'-C-methylene-beta-D-ribofuranosyl)-uridineacil; 5'-N3-3'-O-TBDMS-LNA-Ur

5'-O-DMTr-2'-O-Me-A(iBu)

Description: 5'-O-DMTr-2'-O-Me-A(iBu) consists of a dimethoxytrityl (DMTr) protecting group attached to the 5' hydroxyl, along with an isobutyl (iBu) group attached to the 2' position of ribose. It is used in oligonucleotide synthesis to introduce protecting groups and provide specific chemical properties.

CAT: BRP-01015

Molecular Formula: C36H39N5O7

Molecular Weight: 653.74

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at -20 °C

InChIKey: PNFDGHXTXJOSKF-JYYIKNSZSA-N

IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)isobutyramide

InChI: InChI=1S/C36H39N5O7/c1-22(2)34(43)40-32-29-33(38-20-37-32)41(21-39-29)35-31(46-5)30(42)28(48-35)19-47-36(23-9-7-6-8-10-23,24-11-15-26(44-3)16-12-24)25-13-17-27(45-4)18-14-25/h6-18,20-22,28,30-31,35,42H,19H2,1-5H3,(H,37,38,40,43)/t28-,30-,31-,35-/m1/s1

Synonyms: N2-isobutyryl-5'-O-4,4'-dimethoxytrityl)-2'-O-methyl-adenosine

7-Me-2'-O-Me-Gr

Description: 7-Me-2'-O-Me-Gr is a modified nucleoside used in oligonucleotide synthesis. It consists of a methyl group (Me) attached to the 7th position of guanine and a methyl (Me) group at the 2' position of ribose. This modification is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, allowing for tailored modifications and improved nucleic acid properties.

CAT: BRP-01016

CAS: 1125657-23-9

Molecular Formula: C12H17N5O5

Molecular Weight: 311.29

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InChIKey: CJRPFMAFZQADLD-IOSLPCCCSA-N

CanonicalSMILES: CN1C=[N+](C2=C1C(=NC(=N2)N)[O-])C3C(C(C(O3)CO)O)OC

IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-7-methylpurin-9-ium-6-olate

InChI: InChI=1S/C12H17N5O5/c1-16-4-17(9-6(16)10(20)15-12(13)14-9)11-8(21-2)7(19)5(3-18)22-11/h4-5,7-8,11,18-19H,3H2,1-2H3,(H2-,13,14,15,20)/t5-,7-,8-,11-/m1/s1

Synonyms: 7-Me-2'-O-Me-guanosine; (9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-7-methyl-6-oxo-6,9-dihydro-3H-purin-7-ium-2-yl)amide; 2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-7-methyl-9H-purin-7-ium-6-olate; Guanosine, 7-methyl-2'-O-methyl-, inner salt

Related CAS: 1093268-98-4 (7-Methyl-2'-O-methylguanosine)

3'-O-propargyl-2-amino-Ar

Description: 3'-O-propargyl-2-amino-Ar is a modified nucleoside used in oligonucleotide synthesis. It consists of a propargyl group attached to the 3' position of ribose and a 2-amino group attached to the adenine base. This modification is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, enabling conjugation or further modifications for various applications.

CAT: BRP-01017

CAS: 1451256-05-5

Molecular Formula: C13H16N6O4

Molecular Weight: 320.31

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Density: 1.76±0.1 g/cm3

Boiling Point: 757.8±70.0 °C at 760 mmHg

InChIKey: BVSATFBMHIPHQP-WOUKDFQISA-N

CanonicalSMILES: C#CCOC1C(OC(C1O)N2C=NC3=C(N=C(N=C32)N)N)CO

IUPAC Name: (2R,3R,4S,5R)-2-(2,6-diaminopurin-9-yl)-5-(hydroxymethyl)-4-prop-2-ynoxyoxolan-3-ol

InChI: InChI=1S/C13H16N6O4/c1-2-3-22-9-6(4-20)23-12(8(9)21)19-5-16-7-10(14)17-13(15)18-11(7)19/h1,5-6,8-9,12,20-21H,3-4H2,(H4,14,15,17,18)/t6-,8-,9-,12-/m1/s1

Synonyms: 3'-O-propargyl-2-amino-adenosine; 2-Amino-3'-O-2-propyn-1-yladenosine

7-Me-3'-O-Me-Gr

Description: 7-Me-3'-O-Me-Gr is a modified nucleoside used in oligonucleotide synthesis. It consists of a methyl group (Me) attached to the 7th position of guanine and a methyl (Me) group at the 3' position of ribose. This modification is employed in oligonucleotide synthesis to introduce specific functionalities or properties into the oligonucleotide sequence, allowing for tailored modifications and improved nucleic acid properties.

CAT: BRP-01018

Molecular Formula: C12H17N5O5

Molecular Weight: 311.29

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InChIKey: BQGWLQOGQUOEIW-IOSLPCCCSA-N

IUPAC Name: 2-amino-9-((2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxytetrahydrofuran-2-yl)-7-methyl-9H-purin-7-ium-6-olate

InChI: InChI=1S/C12H17N5O5/c1-16-4-17(9-6(16)10(20)15-12(13)14-9)11-7(19)8(21-2)5(3-18)22-11/h4-5,7-8,11,18-19H,3H2,1-2H3,(H2-,13,14,15,20)/t5-,7-,8-,11-/m1/s1

Synonyms: 7-methyl-3'-O-methyl-guanosine

2,3'-Anhydro-5-Me-Ur

Description: 2,3'-Anhydro-5-Me-Ur is a modified nucleoside used in oligonucleotide synthesis. It is a derivative of uridine where the hydroxyl groups at the 2' and 3' positions of ribose are eliminated, and a methyl (Me) group is attached to the 5th position of the uracil base. This modification is employed in oligonucleotide synthesis to introduce specific structural features or properties into the oligonucleotide sequence, allowing for various applications in research and biotechnology.

CAT: BRP-01019

Molecular Formula: C10H14N2O5

Molecular Weight: 242.23

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InChIKey: OPNAHQQKNKLRRL-IWLPKDRNSA-N

IUPAC Name: (2R,3R,5R,11R)-11-hydroxy-3-(hydroxymethyl)-8-methyl-2,3,10,10a-tetrahydro-5H,9H-2,5-methanopyrimido[2,1-b][1,5,3]dioxazepin-9-one

InChI: InChI=1S/C10H14N2O5/c1-4-2-12-9-6(14)7(5(3-13)16-9)17-10(12)11-8(4)15/h2,5-7,9-10,13-14H,3H2,1H3,(H,11,15)/t5-,6-,7+,9-,10?/m1/s1

Synonyms: 2,3'-Anhydro-5-Me-uridine

2',4-Anhydro-pU

Description: 2',4-Anhydro-pU is a modified nucleoside used in oligonucleotide synthesis. It is a derivative of pseudouridine where the hydroxyl groups at the 2' and 4' positions of ribose are eliminated. This modification is employed in oligonucleotide synthesis to introduce specific structural features or properties into the oligonucleotide sequence, which may influence RNA structure, stability, or interactions with other molecules.

CAT: BRP-01020

Molecular Formula: C9H12N2O5

Molecular Weight: 228.20

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InChIKey: RVTBSCYISWGRMI-KEWYIRBNSA-N

CanonicalSMILES: O=C1NC=C2C(OC3C(O)C(OC23)CO)N1

IUPAC Name: (4bS,6R,7R,7aR)-7-hydroxy-6-(hydroxymethyl)-3,4b,6,7,7a,8a-hexahydrofuro[2',3':4,5]furo[2,3-d]pyrimidin-2(1H)-one

InChI: InChI=1S/C9H12N2O5/c12-2-4-5(13)7-6(15-4)3-1-10-9(14)11-8(3)16-7/h1,4-8,12-13H,2H2,(H2,10,11,14)/t4-,5-,6+,7-,8?/m1/s1

Synonyms: 2',4-Anhydro-pseudouridine; Furo[2',3':4,5]furo[2,3-d]pyrimidin-2(1H)-one, 3,4b,6,7,7a,8a-hexahydro-7-hydroxy-6-(hydroxymethyl)-, (4bS,6R,7R,7aR)-

2-Iodo-9-β-D-ribofuranosyl-9H-purine

Description: 2-Iodo-9-β-D-ribofuranosyl-9H-purine is a modified nucleoside used in oligonucleotide synthesis. It consists of an iodine atom (I) attached to the 2-position of 9-β-D-ribofuranosyl-9H-purine. This modification is employed in oligonucleotide synthesis for various applications, including labeling, cross-linking studies, or structural probing experiments.

CAT: BRP-01021

CAS: 125425-46-9

Molecular Formula: C10H11IN4O4

Molecular Weight: 378.12

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Density: 2.53±0.1 g/cm3

Melting Point: 163-165 °C

Boiling Point: 695.9±65.0 °C at 760 mmHg

InChIKey: JNWLMGAOAHHDJY-JXOAFFINSA-N

CanonicalSMILES: IC=1N=CC=2N=CN(C2N1)C3OC(CO)C(O)C3O

IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(2-iodo-9H-purin-9-yl)tetrahydrofuran-3,4-diol

InChI: InChI=1S/C10H11IN4O4/c11-10-12-1-4-8(14-10)15(3-13-4)9-7(18)6(17)5(2-16)19-9/h1,3,5-7,9,16-18H,2H2/t5-,6-,7-,9-/m1/s1

Synonyms: 2-Iodo-purine-ribose; 2-I-purine-ribose; 9H-Purine, 2-iodo-9-β-D-ribofuranosyl-

1-Methylpseudoisocytidine

Description: 1-Methylpseudoisocytidine is a modified nucleoside used in oligonucleotide synthesis. It is a derivative of pseudoisocytidine where a methyl group (Me) is attached to the nitrogen atom. This modification is employed in oligonucleotide synthesis to introduce specific structural features or properties into the oligonucleotide sequence, allowing for various applications in RNA research and therapeutics.

CAT: BRP-01022

CAS: 80229-06-7

Molecular Formula: C10H15N3O5

Molecular Weight: 257.25

Purity: ≥98% by HPLC

Appearance: White, off-white to light yellow powder

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Storage: Store at -20 °C

Density: 1.79±0.1 g/cm3

Boiling Point: 540.4±60.0 °C at 760 mmHg

InChIKey: MIXBUOXRHTZHKR-XUTVFYLZSA-N

CanonicalSMILES: CN1C=C(C(=O)N=C1N)C2C(C(C(O2)CO)O)O

IUPAC Name: 2-amino-5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpyrimidin-4-one

InChI: InChI=1S/C10H15N3O5/c1-13-2-4(9(17)12-10(13)11)8-7(16)6(15)5(3-14)18-8/h2,5-8,14-16H,3H2,1H3,(H2,11,12,17)/t5-,6-,7-,8+/m1/s1

Synonyms: N1-methyl-Pseudoisocytidine; 2-Amino-5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1-methylpyrimidin-4(1H)-one; N1-Me-Pseudo-iso-Cytidine; 2-Amino-1-methyl-5-β-D-ribofuranosyl-4(1H)-pyrimidinone; 1-Methyl-pseudoisocytidine