What are nucleosides used for?

Nucleosides are base molecules used as starting materials for synthesizing nucleotides and phosphoramidites.

What is the difference between nucleosides and nucleotides?

Nucleosides lack phosphate groups, while nucleotides contain one or more phosphates required for enzymatic reactions.

Are nucleosides used directly in enzymatic reactions?

Nucleosides are typically chemically modified before being used in enzymatic workflows.

Can nucleosides be chemically modified?

Yes, modified nucleosides are widely used to introduce structural or functional changes in nucleic acids.

Why is nucleoside purity important?

High purity ensures correct downstream synthesis of nucleotides and phosphoramidites with predictable performance.

Nucleosides - RNA / BOC Sciences

2',3'-Di-O-acetyluridine

Description: 2',3'-Di-O-acetyluridine, a compound extensively utilized in the biomedical domain, exhibits remarkable potential in therapeutics. Notably, it has exhibited substantial efficacy in mitigating diverse ailments including neurological disorders and liver diseases. Research activities are currently underway to unravel the intricate mechanisms of its action and identify precise drug targets.

CAT: BRP-01692

CAS: 29108-90-5

Molecular Formula: C13H16N2O8

Molecular Weight: 328.27

Purity: ≥95%

Appearance: White Crystalline Powder

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Storage: Store at -20°C

Density: 1.49±0.10 g/cm3

Melting Point: 142-143 °C

InChIKey: BUHMZKLSFGZBHP-HJQYOEGKSA-N

CanonicalSMILES: CC(=O)OC1C(OC(C1OC(=O)C)N2C=CC(=O)NC2=O)CO

IUPAC Name: [(2R,3R,4R,5R)-4-acetyloxy-5-(2,4-dioxopyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] acetate

InChI: InChI=1S/C13H16N2O8/c1-6(17)21-10-8(5-16)23-12(11(10)22-7(2)18)15-4-3-9(19)14-13(15)20/h3-4,8,10-12,16H,5H2,1-2H3,(H,14,19,20)/t8-,10-,11-,12-/m1/s1

Synonyms: 2',3'-Diacetyl Uridine; 2'-O,3'-O-Diacetyluridine; 2',3'-Di-O-acetyl-D-uridine; Uridine, 2',3'-diacetate; (2R,3R,4R,5R)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl diacetate; 2',3'-O,O-diacetyluridine

L-Guanosine

Description: L-Guanosine is a remarkable nucleoside widely utilized in exploring intricate neurological disorders, including Alzheimer's disease and dementia. Furthermore, L-Guanosine's pivotal role in RNA synthesis has propelled its prominence in the realm of antiviral drug development, specifically in the context of studying pernicious RNA viruses, such as hepatitis C.

CAT: BRP-01729

CAS: 26578-09-6

Molecular Formula: C10H13N5O5

Molecular Weight: 283.24

Purity: ≥97% by HPLC

Appearance: White to Off-white Crystalline Powder

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Storage: Store at 2-8°C

Density: 2.25±0.1 g/cm3 (Predicted)

Boiling Point: 775.9±70.0°C (Predicted)

InChIKey: NYHBQMYGNKIUIF-GIMIYPNGSA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(NC2=O)N

IUPAC Name: 2-amino-9-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m0/s1

Synonyms: Beta-L-ribo Guanosine; 9-(b-L-Ribofuranosyl)guanine; L-rG; 2-amino-9-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-β-L-ribofuranosyl-; 2-Amino-9-(β-L-ribofuranosyl)-1,9-dihydro-6H-purin-6-one; 2-Amino-1,9-dihydro-9-β-L-ribofuranosyl-6H-purin-6-one

5-Methoxyuridine

Description: 5-Methoxyuridine is an analog of Uridine and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist.

CAT: BRP-01759

CAS: 35542-01-9

Molecular Formula: C10H14N2O7

Molecular Weight: 274.23

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: Store at 2-8 °C

Density: 1.65±0.1 g/cm3 (Predicted)

Melting Point: 217-218°C

Symbol: mo⁵U

InChIKey: ZXIATBNUWJBBGT-JXOAFFINSA-N

Solubility: Soluble in Water (50 mg/mL, clear, colorless)

CanonicalSMILES: COC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxypyrimidine-2,4-dione

InChI: InChI=1S/C10H14N2O7/c1-18-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)19-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1

Synonyms: Uridine, 5-methoxy-; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidine-2,4(1H,3H)-dione; 5-OMe-Ur

2-Amino-6-chloropurine-9-(2'-O-methyl)riboside

Description: 2-Amino-6-chloropurine-9-(2'-O-methyl)riboside is a remarkable biomedical entity, diligently confronting the pernicious wrath of herpes simplex virus and varicella-zoster virus, rendering them futile through the inhibition of viral DNA synthesis and replication.

CAT: BRP-01768

CAS: 194034-59-8

Molecular Formula: C11H14ClN5O4

Molecular Weight: 315.71

Purity: ≥95%

Appearance: White Solid

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Storage: Store at 2-8 °C

Density: 1.94±0.1 g/cm3

Boiling Point: 675.6±65.0°C at 760 mmHg

InChIKey: MDXXTTIZSFJMOD-KQYNXXCUSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(N=C3Cl)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol

InChI: InChI=1S/C11H14ClN5O4/c1-20-7-6(19)4(2-18)21-10(7)17-3-14-5-8(12)15-11(13)16-9(5)17/h3-4,6-7,10,18-19H,2H2,1H3,(H2,13,15,16)/t4-,6-,7-,10-/m1/s1

Synonyms: 6-Chloro-2'-O-methylguanosine; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol; 2-Amino-6-chloro-9-(2'-O-methyl-beta-D-ribofuranosyl)-9H-purine; 6-Chloro-9-(2-O-methyl-β-D-ribofuranosyl)-9H-purin-2-amine; 2'-O-Methyl-2-amino-6-chloropurine riboside

2'-O-Methyl-2-thiouridine

Description: 2'-O-Methyl-2-thiouridine is a valuable compound widely used in biomedicine. It acts as an RNA modification tool, incorporating into RNA molecules during synthesis. This powerful molecule exhibits antiviral activity against various viral infections, making it a potential therapeutic option for treating RNA virus-associated diseases. Its unique properties and versatility make it an essential tool for studying RNA biology and developing antiviral therapies.

CAT: BRP-01772

CAS: 113886-72-9

Molecular Formula: C10H14N2O5S

Molecular Weight: 274.29

Purity: ≥95%

Appearance: Off-white to Brown Powder

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Storage: Store at 2-8 °C

Density: 1.55±0.1 g/cm3 (Predicted)

Symbol: s²Um

InChIKey: WARUUAMZJXEUEA-ZOQUXTDFSA-N

CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)NC2=S)CO)O

IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2-sulfanylidenepyrimidin-4-one

InChI: InChI=1S/C10H14N2O5S/c1-16-8-7(15)5(4-13)17-9(8)12-3-2-6(14)11-10(12)18/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,18)/t5-,7-,8-,9-/m1/s1

Synonyms: 2-thio-2'-O-methyluridine; Uridine, 2'-O-methyl-2-thio-; 1-(2-O-Methyl-β-D-ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 4(1H)-Pyrimidinone, 2,3-dihydro-1-(2-O-methyl-β-D-ribofuranosyl)-2-thioxo-; 1-((2R,3R,4R,5R)-4-Hydroxy-5-hydroxymethyl-3-methoxy-tetrahydro-furan-2-yl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

1-(b-D-Xylofuranosyl)uracil

Description: 1-(b-D-Xylofuranosyl)uracil, a potent nucleoside analogue, has proven efficacy in treating herpes simplex virus infections as an antiviral agent. Its active mechanism, closely resembling that of natural nucleosides, gives it the ability to impair viral replication, making it a promising therapeutic option for herpes simplex infections.

CAT: BRP-01776

CAS: 16535-78-7

Molecular Formula: C9H12N2O6

Molecular Weight: 244.20

Purity: ≥95%

Appearance: White or off-white solid

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Storage: Store at -20°C

Density: 1.674±0.06 g/cm3 (Predicted)

Melting Point: 158-158.5°C

InChIKey: DRTQHJPVMGBUCF-PXBUCIJWSA-N

Solubility: Soluble in Ethanol

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6+,7-,8-/m1/s1

Synonyms: Xylo-uridine; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(beta-D-Xylofuranosyl)uracil; 2,4(1H,3H)-Pyrimidinedione, 1-β-D-xylofuranosyl-; 9-(β-D-Xylofuranosyl)uracil; 1-β-D-Xylofuranosyl-2,4(1H,3H)-pyrimidinedione; 1-Xylosyluracil; 1-β-D-Xylofuranosyluracil; 1-β-D-Xylosyluracil; β-D-Xylouracil

5,6-Dihydrouridine

Description: 5,6-Dihydrouridine is an intermediate used in the synthesis of 3,4,5,6-Tetrahydrouridine (>80%), which is a derivative of Uridine. Tetrahydrouridine (THU) is a potent inhibitor of cytidine. It inhibits cell proliferation through cell cycle regulation regardless of cytidine deaminase expression levels deaminase (CDA), and thus can be used as a potential and promising treatment for tumors with highly expressed CDA.

CAT: BRP-01777

CAS: 5627-05-4

Molecular Formula: C9H14N2O6

Molecular Weight: 246.22

Purity: ≥95%

Appearance: White to Off-White Solid

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Storage: Store at 2-8°C under inert atmosphere

Density: 1.614±0.06 g/cm3 (Predicted)

Melting Point: >64°C (dec.)

Symbol: D

InChIKey: ZPTBLXKRQACLCR-XVFCMESISA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione

InChI: InChI=1S/C9H14N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4,6-8,12,14-15H,1-3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1

Synonyms: Dihydro-1-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione; Dihydrouridine; 1-β-D-Ribofuranosyl-hydrouracil; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)dihydropyrimidine-2,4(1H,3H)-dione; 1-(β-L-Ribofuranosyl)dihydro-2,4(1H,3H)-pyrimidinedione

2-Thiouridine

Description: 2-Thiouridine, an esteemed biomedical marvel, is renowned for its profound efficacy in combatting malignant neoplasms and thwarting viral affections. This exalted nucleoside derivative ingeniously integrates itself into RNA, instigating the impeding of viral propagation and invoking apoptosis within neoplastic entities. Its exceptional anti-tumorigenic and antiviral prowess has propelled 2-Thiouridine to the vanguard of biomedical exploration and therapeutic breakthroughs.

CAT: BRP-01780

CAS: 20235-78-3

Molecular Formula: C9H12N2O5S

Molecular Weight: 260.27

Purity: ≥95%

Appearance: White to Off-white Solid

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5 g	$599	In stock

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Storage: Store at 2-8°C under inert atmosphere

Density: 1.72±0.1 g/cm3 at 20°C, 760 Torr

Melting Point: 216-218 °C

Symbol: s²U

InChIKey: GJTBSTBJLVYKAU-XVFCMESISA-N

Solubility: Soluble in DMSO (Slightly, Heated), Water (Slightly, Heated)

CanonicalSMILES: C1=CN(C(=S)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one

InChI: InChI=1S/C9H12N2O5S/c12-3-4-6(14)7(15)8(16-4)11-2-1-5(13)10-9(11)17/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,17)/t4-,6-,7-,8-/m1/s1

Synonyms: 1-β-D-Ribofuranosyl-2-thiouracil; 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; Thiouridine

Binodenoson

Description: Binodenoson is a pharmacologic stress agent specific to the only adenosine receptor necessary for increased cardiac blood flow, the A2A receptor agonist. It is used to diagnose coronary artery disease.

CAT: BRP-01783

CAS: 144348-08-3

Molecular Formula: C17H25N7O4

Molecular Weight: 391.42

Purity: 95%

Appearance: White solid

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Storage: Store at -20 °C

Density: 1.76±0.1 g/cm3

Melting Point: 154-157°C

Boiling Point: 765.6±70.0 °C at 760 mmHg

Application: Purinergic P1 Receptor Agonists

InChIKey: XJFMHMFFBSOEPR-XNIJJKJLSA-N

Solubility: Soluble in DMSO: 125 mg/mL

CanonicalSMILES: C1CCC(CC1)C=NNC2=NC(=C3C(=N2)N(C=N3)C4C(C(C(O4)CO)O)O)N

IUPAC Name: (2R,3R,4S,5R)-2-[6-amino-2-[2-(cyclohexylmethylidene)hydrazinyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C17H25N7O4/c18-14-11-15(22-17(21-14)23-20-6-9-4-2-1-3-5-9)24(8-19-11)16-13(27)12(26)10(7-25)28-16/h6,8-10,12-13,16,25-27H,1-5,7H2,(H3,18,21,22,23)/t10-,12-,13-,16-/m1/s1

Synonyms: MRE0470; MRE-0470; WRC-0470; SHA-174; 2-((Cyclohexylmethylene)hydrazino)adenosine; 2-(Cyclohexylmethylidene hydrazino) adenosine; 2-[2-(Cyclohexylmethylene)hydrazinyl]adenosine; 2-(Cyclohexylmethylidenehydrazino)adenosine; SHA 211; WRC 0470

5-Hydroxyuridine

Description: 5-Hydroxyuridine is an anticancer agent. 5-Hydroxyuridine is a modified nucleoside derived from uridine, commonly found in RNA molecules, especially in transfer RNA (tRNA), where it plays a significant role in RNA structure and function.

CAT: BRP-01788

CAS: 957-77-7

Molecular Formula: C9H12N2O7

Molecular Weight: 260.20

Purity: ≥95%

Appearance: White to Off-White Solid

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Storage: Store at -20°C under inert atmosphere

Density: 1.848±0.1 g/cm3

Melting Point: >240°C (dec.)

Symbol: ho⁵U

InChIKey: QXDXBKZJFLRLCM-UAKXSSHOSA-N

Solubility: Soluble in Water (Slightly, Heated, Sonicated)

CanonicalSMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-hydroxypyrimidine-2,4-dione

InChI: InChI=1S/C9H12N2O7/c12-2-4-5(14)6(15)8(18-4)11-1-3(13)7(16)10-9(11)17/h1,4-6,8,12-15H,2H2,(H,10,16,17)/t4-,5-,6-,8-/m1/s1

Synonyms: Uridine, 5-hydroxy-; 1-(beta-D-ribofuranosyl)-5-hydroxypyrimidine-2,4(1H,3H)-dione; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-hydroxy-pyrimidine-2,4-dione; 1-β-D-Ribofuranosylisobarbituric acid; Isobarbituridine

3'-O-Propargyladenosine

Description: 3'-O-Propargyladenosine, a pharmaceutical product extensively employed within the biomedical industry, exhibits remarkable efficacy in treating numerous ailments, inclusive of cancer and viral infections. Via its potent antineoplastic properties, it diligently impedes the proliferation of malignant tumors, while commendably repressing viral replication as an antiviral agent.

CAT: BRP-01791

CAS: 2305416-10-6

Molecular Formula: C13H15N5O4

Molecular Weight: 305.29

Purity: 95%

Appearance: White to off-white solid

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Storage: Store at 2-8 °C

Density: 1.7±0.1 g/cm3

Boiling Point: 655.1±65.0°C at 760 mmHg

InChIKey: SLZDQTVTJDVDJE-QYVSTXNMSA-N

CanonicalSMILES: C#CCO[C@@H]1[C@H](O[C@H]([C@@H]1O)N2C=NC3=C(N=CN=C32)N)CO

IUPAC Name: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-prop-2-ynoxyoxolan-3-ol

InChI: InChI=1S/C13H15N5O4/c1-2-3-21-10-7(4-19)22-13(9(10)20)18-6-17-8-11(14)15-5-16-12(8)18/h1,5-7,9-10,13,19-20H,3-4H2,(H2,14,15,16)/t7-,9-,10-,13-/m1/s1

Synonyms: 3'-(O-propargyl) Adenosine; 3'-O-2-Propyn-1-yladenosine; 3'-O-Propargyl-D-adenosine; (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-ol

N6,2'-O-dimethyladenosine

Description: N6,2'-O-dimethyladenosine is a naturally occurring modified nucleoside in RNA. It is known to play roles in regulating RNA stability, translation, and other cellular processes.

CAT: BRP-01795

CAS: 57817-83-1

Molecular Formula: C12H17N5O4

Molecular Weight: 295.29

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at -20°C under inert atmosphere

Density: 1.7±0.1 g/cm3

Melting Point: 177-179°C

Boiling Point: 606.5±65.0°C at 760 mmHg

Symbol: m⁶Am

InChIKey: GRYSXUXXBDSYRT-WOUKDFQISA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Sonicated)

CanonicalSMILES: CNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)OC

IUPAC Name: (2R,3R,4R,5R)-2-(hydroxymethyl)-4-methoxy-5-[6-(methylamino)purin-9-yl]oxolan-3-ol

InChI: InChI=1S/C12H17N5O4/c1-13-10-7-11(15-4-14-10)17(5-16-7)12-9(20-2)8(19)6(3-18)21-12/h4-6,8-9,12,18-19H,3H2,1-2H3,(H,13,14,15)/t6-,8-,9-,12-/m1/s1

Synonyms: N6-Methyl-2'-O-methyladenosine; Adenosine, N-methyl-2'-O-methyl-; N(6),O(2')-Dimethyladenosine; N-Methyl-2'-O-methyladenosine; 2'-O-Methyl-6-methyladenosine; 6-Methyl-2'-O-methyladenosine; N6,O2'-Dimethyladenosine; Sulodexide

4-Thiouridine

Description: Nucleotide analogue is essential to cell growth in certain bacterial species, which is also able to chelate with certain metal ions, and in tRNA. It can act as a built-in antiphotomutagenic agent protecting Escherichia coli cells against mutagenesis.

CAT: BRP-01799

CAS: 13957-31-8

Molecular Formula: C9H12N2O5S

Molecular Weight: 260.27

Purity: ≥95%

Appearance: Light Yellow to Yellow Solid

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Storage: Store at 2-8°C

Density: 1.72 g/cm3

Melting Point: 80-83°C; 139-140°C (ethanol)

Application: Affinity Labels

Symbol: s⁴U

InChIKey: ZLOIGESWDJYCTF-XVFCMESISA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Sonicated)

CanonicalSMILES: C1=CN(C(=O)NC1=S)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidenepyrimidin-2-one

InChI: InChI=1S/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17)/t4-,6-,7-,8-/m1/s1

Synonyms: Uridine, 4-thio-; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidene-1,2,3,4-tetrahydropyrimidin-2-one; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-4-thioxo-pyrimidin-2-one; 1-beta-D-ribofuranosyl-4-thiouracil; 1-(β-D-Ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone; 4-Thio Uridine

2',3'-Bis-(O-t-butyldimethylsilyl)uridine

Description: 2',3'-Bis-(O-t-butyldimethylsilyl)uridine, a widely utilized compound in the realm of biomedicine, assumes an indispensable function in the amalgamation of nucleoside analogs and antiviral pharmaceuticals, notably AZT and acyclovir. Moreover, it exerts an inhibitory effect on viral replication, rendering it instrumental in combating illnesses such as HIV and herpes. Its exceptional attributes render this biomedical research and drug development tool truly invaluable.

CAT: BRP-01800

CAS: 69504-12-7

Molecular Formula: C21H40N2O6Si2

Molecular Weight: 472.72

Purity: ≥95%

Appearance: White to off-white solid

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Storage: Store at -20 °C

Density: 1.10±0.1 g/cm3

Melting Point: 226-227 °C

InChIKey: FZXFJQVZSQAGPM-VDHUWJSZSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=CC(=O)NC2=O)CO

IUPAC Name: 1-((2R,3R,4R,5R)-3,4-bis((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

InChI: InChI=1S/C21H40N2O6Si2/c1-20(2,3)30(7,8)28-16-14(13-24)27-18(23-12-11-15(25)22-19(23)26)17(16)29-31(9,10)21(4,5)6/h11-12,14,16-18,24H,13H2,1-10H3,(H,22,25,26)/t14-,16-,17-,18-/m1/s1

Synonyms: Uridine, 2',3'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-; 2',3'-Bis-O-tert-butyldimethylsilyluridine; 2'-O,3'-O-Bis(tert-butyldimethylsilyl)uridine; 2',3'-Bis-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine; 2',3'-Bis-O-[(1,1-dimethylethyl)dimethylsilyl]uridine

Nebularine

Description: Nebularine is originally isolated from Agaricus nebularis. Shown to have inhibitory effects against mouse Sarcoma 180 and mycobacteria.

CAT: BRP-01802

CAS: 550-33-4

Molecular Formula: C10H12N4O4

Molecular Weight: 252.23

Purity: ≥ 95% by HPLC

Appearance: Off-white to Beige Solid

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Storage: Store at -20°C

Density: 1.91±0.1 g/cm3

Melting Point: 180-181°C

Boiling Point: 591.6±60.0 °C at 760 mmHg

InChIKey: MRWXACSTFXYYMV-FDDDBJFASA-N

Solubility: Soluble in DMSO (Slightly), Ethanol, Methanol (Slightly)

CanonicalSMILES: C1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O

IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-purin-9-yloxolane-3,4-diol

InChI: InChI=1S/C10H12N4O4/c15-2-6-7(16)8(17)10(18-6)14-4-13-5-1-11-3-12-9(5)14/h1,3-4,6-8,10,15-17H,2H2/t6-,7-,8-,10-/m1/s1

Synonyms: 9-(beta-D-Ribofuranosyl)-9H-purine; Purine riboside; Purine-9-β-D-ribofuranoside; 9-β-D-Ribofuranosyl-9H-purine; Ribosyl-isopurine; N-D-Ribosylpurine; Purinosine; NSC 65423; 6-Deaminoadenosine; 9-β-D-Ribofuranosylpurine; 9-β-D-Ribosyl-9H-purine; Desaminoadenosine; Isopurine, ribosyl-; Ribosylpurine

9-(b-D-Xylofuranosyl)guanine

Description: 9-(β-D-Xylofuranosyl)guanine, a renowned biomedicine product, is widely recognized for its efficaciousness in combating viral infections, particularly those induced by herpes viruses. Functioning as an antiviral agent, this compound effectively hinders the proliferation of viral DNA, thereby mitigating viral burden and alleviating symptoms related to herpes virus infections.

CAT: BRP-01803

CAS: 27462-39-1

Molecular Formula: C10H13N5O5

Molecular Weight: 283.24

Purity: ≥95%

Appearance: White to off-white solid

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Storage: Store at 2-8 °C

Density: 2.25±0.1 g/cm3

Boiling Point: 775.9±70.0°C at 760 mmHg

InChIKey: NYHBQMYGNKIUIF-FTWQFJAYSA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(NC2=O)N

IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5+,6-,9-/m1/s1

Synonyms: 6H-Purin-6-one, 1,9-dihydro-2-amino-9-beta-D-xylofuranosyl-; 2-Amino-9-(β-D-xylofuranosyl)-1,9-dihydro-6H-purin-6-one; 2-Amino-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-Amino-1,9-dihydro-9-β-D-xylofuranosyl-6H-purin-6-one; Guanine, 9-β-D-xylofuranosyl-; 9-β-D-Xylofuranosylguanine; NSC 115607

N1-EthylpseudoUridine

Description: N1-EthylpseudoUridine is an indispensable compound in the biomedical field, demonstrating profound applications encompass disease research, prevention and intervention. This exceptional substance exhibits unparalleled potential in studying viral onslaughts, malignant neoplasms and neurologic afflictions.

CAT: BRP-01804

CAS: 1613529-72-8

Molecular Formula: C11H16N2O6

Molecular Weight: 272.25

Purity: ≥95%

Appearance: White to off-white solid

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5 mg	$298	In stock

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Storage: Storage at 2-8°C

Density: 1.501±0.06 g/cm3

InChIKey: AMMRPAYSYYGRKP-BGZDPUMWSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: CCN1C=C(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1-ethylpyrimidine-2,4(1H,3H)-dione

InChI: InChI=1S/C11H16N2O6/c1-2-13-3-5(10(17)12-11(13)18)9-8(16)7(15)6(4-14)19-9/h3,6-9,14-16H,2,4H2,1H3,(H,12,17,18)/t6-,7-,8-,9+/m1/s1

Synonyms: 1-Ethylpseudouridine; 1-ethyl-pseudouridine; 2,4(1H,3H)-Pyrimidinedione, 1-ethyl-5-β-D-ribofuranosyl-; 1-Ethyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione

8-Iodo-guanosine

Description: 8-Iodo-guanosine, a chemical compound used in biomedical research, has proven instrumental in studying the impacts of purine nucleoside analogs on cancers and viral infections. As an iodine-substituted guanosine derivative, it exhibits the potential to act as an inhibitor of RNA viruses like HIV and hepatitis C.

CAT: BRP-01848

CAS: 18438-99-8

Molecular Formula: C10H12IN5O5

Molecular Weight: 409.14

Purity: ≥97% by HPLC

Appearance: Solid

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Density: 2.85±0.1 g/cm3 (Predicted)

InChIKey: PBEHMRJESXYIKX-UMMCILCDSA-N

CanonicalSMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2I)O)O)O

IUPAC Name: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-iodo-1H-purin-6-one

InChI: InChI=1S/C10H12IN5O5/c11-9-13-3-6(14-10(12)15-7(3)20)16(9)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H3,12,14,15,20)/t2-,4-,5-,8-/m1/s1

Synonyms: 8-Iodoguanosine; 8-I-rG; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-iodo-1H-purin-6(9H)-one; 8-Iodocoumarin; NSC 79218

2'-Deoxy-2'-fluoro-5-iodouridine

Description: It is an antiviral drug and nucleoside analogue with anti-hepatitis B activity.

CAT: BRP-01855

CAS: 55612-21-0

Molecular Formula: C9H10FIN2O5

Molecular Weight: 372.09

Purity: ≥95%

Appearance: White to Off-white Powder

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100 mg	$358	In stock

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Storage: Store at 2-8°C

Density: 2.18±0.1 g/cm3 (Predicted)

Melting Point: 216-218°C

InChIKey: IPVFGAYTKQKGBM-UAKXSSHOSA-N

CanonicalSMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)F)I

IUPAC Name: 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione

InChI: InChI=1S/C9H10FIN2O5/c10-5-6(15)4(2-14)18-8(5)13-1-3(11)7(16)12-9(13)17/h1,4-6,8,14-15H,2H2,(H,12,16,17)/t4-,5-,6-,8-/m1/s1

Synonyms: 1-(2'-Deoxy-2'-fluoro-beta-D-ribofuranosyl)-5-iodouracil; 2'-epi-Fialuridine; FIRU; 5-Iodo-1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)uracil; 1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidine-2,4(1H,3H)-dione

N6-(2-Hydroxyethyl)adenosine

Description: It is an anticonvulsant by activating the adenosine A1 receptor (AA1R).

CAT: BRP-01863

CAS: 4338-48-1

Molecular Formula: C12H17N5O5

Molecular Weight: 311.29

Purity: ≥95%

Appearance: White to Off-white Solid

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5 g	$699	In stock

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Storage: Store at -20°C

Density: 1.88±0.1 g/cm3

Melting Point: 194-195°C

Boiling Point: 725.8±70.0°C at 760 mmHg

InChIKey: BBOCDRLDMQHWJP-WOUKDFQISA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)NCCO

IUPAC Name: (2R,3R,4S,5R)-2-[6-(2-hydroxyethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C12H17N5O5/c18-2-1-13-10-7-11(15-4-14-10)17(5-16-7)12-9(21)8(20)6(3-19)22-12/h4-6,8-9,12,18-21H,1-3H2,(H,13,14,15)/t6-,8-,9-,12-/m1/s1

Synonyms: (2R,3R,4S,5R)-2-(6-((2-Hydroxyethyl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; N-(2-Hydroxyethyl)adenosine; Adenosine, N-(2-hydroxyethyl)-; N-hydroxyethyl adenosine; 6-(2-Hydroxyethyl)amino-9-beta-D-ribofuranosylpurine; NSC 54251; 6-[(2-Hydroxyethyl)amino]-9-β-D-ribofuranosylpurine; 6-Hydroxyethyladenosine