What are nucleosides used for?

Nucleosides are base molecules used as starting materials for synthesizing nucleotides and phosphoramidites.

What is the difference between nucleosides and nucleotides?

Nucleosides lack phosphate groups, while nucleotides contain one or more phosphates required for enzymatic reactions.

Are nucleosides used directly in enzymatic reactions?

Nucleosides are typically chemically modified before being used in enzymatic workflows.

Can nucleosides be chemically modified?

Yes, modified nucleosides are widely used to introduce structural or functional changes in nucleic acids.

Why is nucleoside purity important?

High purity ensures correct downstream synthesis of nucleotides and phosphoramidites with predictable performance.

Nucleosides - RNA / BOC Sciences

EIDD-2801

Description: EIDD-2801, derived from N4-hydroxycytidine, is an oral bioavailable broad-spectrum antiviral compound that is effective against SARS-CoV2 infection.

CAT: BRP-01870

CAS: 2492423-29-5

Molecular Formula: C13H19N3O7

Molecular Weight: 329.31

Purity: 95%

Appearance: White to off-white solid

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Storage: Store at 2-8 °C, sealed storage, away from moisture

Density: 1.62±0.1 g/cm3

Melting Point: 156-159 °C

Application: Antiviral Agents

InChIKey: HTNPEHXGEKVIHG-QCNRFFRDSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: CC(C)C(=O)OCC1C(C(C(O1)N2C=CC(=NC2=O)NO)O)O

IUPAC Name: [(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methyl 2-methylpropanoate

InChI: InChI=1S/C13H19N3O7/c1-6(2)12(19)22-5-7-9(17)10(18)11(23-7)16-4-3-8(15-21)14-13(16)20/h3-4,6-7,9-11,17-18,21H,5H2,1-2H3,(H,14,15,20)/t7-,9-,10-,11-/m1/s1

Synonyms: Molnupiravir; EIDD 2801; EIDD2801; MK-4482; WHO 11853; N4-Hydroxycytidine, 5'-isopropyl ester; beta-D-N4 Hydroxycytidine-5'-isopropyl ester; Uridine, 4-oxime, 5'-(2-methylpropanoate), (4Z)-; EIDD 1931-isopropyl ester; Lagevrio; MK-4482; β-D-N4 hydroxycytidine-5'-isopropyl ester

Related CAS: 2349386-89-4 (Deleted CAS)

2-Thioadenosine

Description: 2-Thioadenosine is a modified nucleoside where the oxygen atom at the 2-position of the adenosine molecule is replaced with a sulfur atom. 2-Thioadenosine is an important modified nucleoside used in research to understand nucleic acid biochemistry and to develop potential therapeutic agents. Its unique sulfur substitution provides distinct properties that can be leveraged in various biological and medical applications. It is also an impurity of Cangrelor.

CAT: BRP-01906

CAS: 43157-50-2

Molecular Formula: C10H13N5O4S

Molecular Weight: 299.31

Purity: ≥95%

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Storage: Store at 2-8 °C, protect from light

Density: 2.18±0.1 g/cm3

Melting Point: >178 °C

Boiling Point: 544.5±60.0 °C at 760 mmHg

InChIKey: LTESOZAUMTUKQX-UUOKFMHZSA-N

CanonicalSMILES: C1=NC2=C(NC(=S)N=C2N1C3C(C(C(O3)CO)O)O)N

IUPAC Name: 6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purine-2-thione

InChI: InChI=1S/C10H13N5O4S/c11-7-4-8(14-10(20)13-7)15(2-12-4)9-6(18)5(17)3(1-16)19-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,20)/t3-,5-,6-,9-/m1/s1

Synonyms: 6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purine-2-thione; Cangrelor Impurity 6; 2-Mercaptoadenosine; Adenosine, 1,2-dihydro-2-thioxo-; 2,3-Dihydro-2-thioxoadenosine; Adenosine, 2,3-dihydro-2-thioxo-

((3aR,4R,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl sulfamate

Description: (3aR,4R,6R,6aR)-6-(6-amino-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl sulfamate is a complex bio-chemical compound finding prevalent utilization tactically within the spheres of pharmaceutical expeditions. Particularly exploited for antiviral drug architecture, it can combat ailments birthed by the malicious herpes simplex and varicella-zoster viruses.

CAT: BRP-01912

CAS: 112921-00-3

Molecular Formula: C13H18N6O6S

Molecular Weight: 386.38

Purity: 95%

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Storage: Store at -20°C

Density: 1.96±0.1 g/cm3(Predicted)

Melting Point: 194-196 °C

Boiling Point: 663.8±65.0 °C at 760 mmHg

InChIKey: PCKRSJUZRCXCIR-UHFFFAOYSA-N

CanonicalSMILES: CC1(OC2C(OC(C2O1)N3C=NC4=C(N=CN=C43)N)COS(=O)(=O)N)C

IUPAC Name: [4-(6-aminopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methyl sulfamate

InChI: InChI=1S/C13H18N6O6S/c1-13(2)24-8-6(3-22-26(15,20)21)23-12(9(8)25-13)19-5-18-7-10(14)16-4-17-11(7)19/h4-6,8-9,12H,3H2,1-2H3,(H2,14,16,17)(H2,15,20,21)

Synonyms: Adenosine, 2',3'-O-(1-methylethylidene)-, 5'-sulfamate; 2',3'-O-(1-Methylethylidene)adenosine, 5'-sulfamate

Clevudine

Description: Clevudine is an inhibitor of hepatitis B virus (HBV). It is metabolized in cells by the cellular thymidine kinase as well as deoxycytidine kinase to its monophosphate, and subsequently to the di- and triphosphate, which are biologically active.

CAT: BRP-01918

CAS: 163252-36-6

Molecular Formula: C10H13FN2O5

Molecular Weight: 260.22

Purity: ≥98% by HPLC

Appearance: White Solid

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Storage: Store at -20°C

Density: 1.55±0.1 g/cm3

Melting Point: 184-185 °C

Application: Antiviral Agents

InChIKey: GBBJCSTXCAQSSJ-XQXXSGGOSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)F

IUPAC Name: 1-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

InChI: InChI=1S/C10H13FN2O5/c1-4-2-13(10(17)12-8(4)16)9-6(11)7(15)5(3-14)18-9/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6+,7-,9-/m0/s1

Synonyms: 1-(2'-Deoxy-2'-fluoro-β-L-arabinofuranosyl)-5-methyluracil; L-FMAU; 1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; L FMAU; LFMAU; Levovir; 2'-Fluoro-5-methyl-b-L-arabinofuranosyluracil

Azvudine

Description: Azvudine is a nucleoside reverse transcriptase inhibitor (NRTI), which exhibits inhibtory effects on HIV, HBV and HCV.

CAT: BRP-01974

CAS: 1011529-10-4

Molecular Formula: C9H11FN6O4

Molecular Weight: 286.22

Purity: ≥95%

Appearance: Off-white Crystalline Powder

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Storage: Store at -20°C

Melting Point: 99.0-100.0°C

InChIKey: KTOLOIKYVCHRJW-XZMZPDFPSA-N

Solubility: Soluble in DMSO (10 mM)

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)F

IUPAC Name: 4-amino-1-[(2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C9H11FN6O4/c10-5-6(18)9(3-17,14-15-12)20-7(5)16-2-1-4(11)13-8(16)19/h1-2,5-7,17-18H,3H2,(H2,11,13,19)/t5-,6-,7+,9+/m0/s1

Synonyms: 4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinocytidine; 4'-Azido-2'-deoxy-2'-fluoroaracytidine; RO-0622; 4-amino-1-((2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2'-deoxy-2'-β-fluoro-4'-azidocytidine; 1-(4'-azido-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)cytosine

5'-O-DMT-N4-benzoyl-2'-fluoro-2'-deoxycytidine

Description: 5'-O-DMT-N4-benzoyl-2'-fluoro-2'-deoxycytidine boasts a promising pharmacological arsenal to combat a range of viral infections. With virucidal efficacy that targets the DNA replication machinery of several virus strains, the drug holds considerable therapeutic potential for cases of hepatitis B and C, as well as herpes and shingles. Furthermore, its anti-neoplastic properties make it a noteworthy exploratory tool for certain types of cancer treatment.

CAT: BRP-01980

CAS: 146954-77-0

Molecular Formula: C37H34FN3O7

Molecular Weight: 651.68

Purity: ≥98% by HPLC

Appearance: White powder

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Storage: Store at 2-8 °C

Density: 1.3±0.1 g/cm3

InChIKey: RAIBEZUVTIPFOJ-NHASGABXSA-N

CanonicalSMILES: COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=NC5=O)NC(=O)C6=CC=CC=C6)F)O

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C37H34FN3O7/c1-45-28-17-13-26(14-18-28)37(25-11-7-4-8-12-25,27-15-19-29(46-2)20-16-27)47-23-30-33(42)32(38)35(48-30)41-22-21-31(40-36(41)44)39-34(43)24-9-5-3-6-10-24/h3-22,30,32-33,35,42H,23H2,1-2H3,(H,39,40,43,44)/t30-,32-,33-,35-/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-N4-benzoyl-2'-fluoro-2'-deoxycytidine; N4-Bz-DMT-2'-F-dC; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-D-cytidine; N4-Benzoyl-5'-O-DMT-2'-fluoro-2'-deoxycytidine; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine; 5'-O-DMTr-2'-F-dC(Bz); 5'-DMT-2'-F-Bz-dC; 5'-O-(4,4'-dimethoxytrityl)-N6-Benzoyl-2'-fluoro-2'-deoxyadenosine; N-{1-{5-O-[bis-(4-methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-D-arabinofuranosyl}-1,2-dihydro-2-oxo-4-pyrimidinyl}-benzamide; N-benzoyl-5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-deoxy-2'-fluoro-Cytidine; 5'-O-DMT-N4-Bz-2'-F-dC

2'-Deoxy-2'-fluorocytidine

Description: 2'-Deoxy-2'-fluorocytidine is a potent inhibitor of the subgenomic hepatitis C virus replicon in Huh-7 cells. 2'-Deoxy-2'-fluorocytidine demonstrated to inhibit Borna Disease virus replication and spread.

CAT: BRP-01998

CAS: 10212-20-1

Molecular Formula: C9H12FN3O4

Molecular Weight: 245.21

Purity: ≥95%

Appearance: White Solid

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100 g	$480	In stock

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Storage: Store at 2-8°C

Density: 1.82±0.1 g/cm3 (Predicted)

Melting Point: >187°C (dec.)

Boiling Point: 500.1±60.0°C (Predicted)

InChIKey: NVZFZMCNALTPBY-XVFCMESISA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)F

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6-,7-,8-/m1/s1

Synonyms: 2'-Fluoro Cytidine; 2'-Fluoro-2'-deoxy-β-D-ribofuranosylcytosine; 2'-Fluoro-2'-deoxycytidine; NSC 529432; 4-amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2'-F-dC

Related CAS: 1820580-34-4 (hydrate)

(2'R)-2'-deoxy-2'-fluoro-2'-C-methyluridine

Description: PSI-6206 is a selective HCV RNA polymerase inhibitor. It is the unphosphorylated parent compound of triphosphate analog PSI-7409, which is a potent inhibitor of the HCV NS5B RNA dependent RNA polymerase.

CAT: BRP-02007

CAS: 863329-66-2

Molecular Formula: C10H13FN2O5

Molecular Weight: 260.22

Purity: ≥95%

Appearance: White to Light Beige Solid

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Storage: Store at -20°C

Density: 1.55±0.1 g/cm3

Melting Point: 237.3-238.0 °C

InChIKey: ARKKGZQTGXJVKW-VPCXQMTMSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Heated)

CanonicalSMILES: CC1(C(C(OC1N2C=CC(=O)NC2=O)CO)O)F

IUPAC Name: 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C10H13FN2O5/c1-10(11)7(16)5(4-14)18-8(10)13-3-2-6(15)12-9(13)17/h2-3,5,7-8,14,16H,4H2,1H3,(H,12,15,17)/t5-,7-,8-,10-/m1/s1

Synonyms: RO-2433; RO 2433; RO2433; PSI6206; PSI 6206; PSI-6206; GS331007; GS-331007; GS 331007; 2'-Deoxy-2'-fluoro-2'-C-methyluridine; Sofosbuvir Metabolite GS331007; 1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine; ZL-01 metabolite M9; 2'-Deoxy-2'-Fluoro-2'-methyluridine

2'-Deoxy-2'-fluoroarabinoadenosine

Description: As an analog of the antitumour and antiviral naturally occurring nucleoside 9-(β-D-arabinofuranosyl)adenine (ara-A), 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine inhibited the growth of T. vaginalis with an IC50 of 0.09μM.

CAT: BRP-02024

CAS: 20227-41-2

Molecular Formula: C26H30N2O5

Molecular Weight: 450.5

Purity: ≥97% by HPLC

Appearance: Solid

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500 mg	$629	In stock
1 g	$998	In stock

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Storage: 4°C, protect from light
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Density: 2.01±0.1 g/cm3

Melting Point: 233-234 °C

Boiling Point: 628.6±65.0 °C at 760 mmHg

Application: Anti-neoplastic; Inhibits the growth of T. vaginalis with an IC50 of 0.09μM

InChIKey: ZGYYPTJWJBEXBC-GQTRHBFLSA-N

Solubility: Soluble in DMSO, not in water.

CanonicalSMILES: CC1=C(C(=O)OC2=C1C=CC(=C2)OCC(CN3CCC(CC3)C(=O)N)O)CC4=CC=CC=C4

IUPAC Name: (2R,3R,4S,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol

InChI: InChI=1S/C10H12FN5O3/c11-5-7(18)4(1-17)19-10(5)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5+,7-,10-/m1/s1

Synonyms: 20227-41-2;9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)adenine;(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol;arabino-F-Ado;CHEMBL2032002;(2R,3R,4S,5R)-5-(6-AMINOPURIN-9-YL)-4-FLUORO-2-(HYDROXYMETHYL)OXOLAN-3-OL;(2R,3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol;C10H12FN5O3;SCHEMBL1389499;123334-75-8;BDBM50452569;MFCD12911815;2??-Deoxy-2??-fluoroarabinoadenosine;AKOS027327937;AC-32315;AS-68707;F13969;A855629;2 inverted exclamation mark -Deoxy-2 inverted exclamation mark -fluoroarabinoadenosine;(2R,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol;9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine;

2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine

Description: It is the impurity C of Clofarabine and is also an anticancer agent.

CAT: BRP-02027

CAS: 103884-98-6

Molecular Formula: C10H12FN5O4

Molecular Weight: 285.23

Purity: ≥95%

Appearance: White to Off-white Powder to Crystals

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Storage: Store at -20°C

Density: 2.17±0.1 g/cm3 (Predicted)

Melting Point: 275-279°C

Boiling Point: 726.1±70.0°C (Predicted)

InChIKey: UXUZARPLRQRNNX-AYQXTPAHSA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)F)N=C(NC2=O)N

IUPAC Name: 2-amino-9-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4+,6-,9-/m1/s1

Synonyms: 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)guanine; 2'-Deoxy-2'-fluoro-beta-D-arabinoguanosine; 2'-deoxy-2'-fluoro-arabino-guanosine; 2'-FANA-Gr; 2-Amino-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-1H-purin-6(9H)-one; 2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one; 2'-Fluoro-Arabinoguanosine; NUK-2

Fiacitabine

Description: Fiacitabine is a selective inhibitior of DNA replication of herpes simplex virus(HSV). It was active at much lower concentrations than arabinosylcytosine, iododeoxyuridine, and arabinosyladenine. It was slightly more active against herpes simplex virus type 1 than acycloquanosine and slightly more toxic to normal cells.

CAT: BRP-02033

CAS: 69123-90-6

Molecular Formula: C9H11FIN3O4

Molecular Weight: 371.10

Purity: ≥95%

Appearance: White to off-white solid

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10 mg	$298	In stock
25 mg	$419	In stock

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Storage: Store at -20 °C

Density: 2.44±0.1 g/cm3 (Predicted)

Boiling Point: 524.6±60.0 °C at 760 mmHg

Flash Point: 271.1±32.9 °C

Application: Antineoplastic Agents

InChIKey: GIMSJJHKKXRFGV-BYPJNBLXSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: C1=C(C(=NC(=O)N1C2C(C(C(O2)CO)O)F)N)I

IUPAC Name: 4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one

InChI: InChI=1S/C9H11FIN3O4/c10-5-6(16)4(2-15)18-8(5)14-1-3(11)7(12)13-9(14)17/h1,4-6,8,15-16H,2H2,(H2,12,13,17)/t4-,5+,6-,8-/m1/s1

Synonyms: 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodocytosine; 5-Iodo-2'-deoxy-2'-fluoro-beta-D-arabinocytidine; FICA; DRG-0077; DRG 0077; DRG0077; FOAC; Fluoroiodoaracytidine; Fluorviodoaracytidine; 4-Amino-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; 1-β-D-2'-Fluoroarabino-5-iodocytosine; 2'-Fluoro-5-iodo-1-β-D-arabinofuranosylcytosine; NSC 382097

Related CAS: 69124-05-6 (monohydrochloride salt)

3'-Deoxy-3'-fluorouridine

Description: 3'-Deoxy-3'-fluorouridine, a compound of utmost significance in the biomedical industry, assumes a pivotal position in the advancement of antiviral pharmaceuticals targeting RNA virus-associated ailments. This exceptional product showcases its robust antiviral efficacy against a multitude of viruses. Through the powerful mechanism of inhibiting viral replication, 3'-Deoxy-3'-fluorouridine emerges as a propitious contender in the ongoing battle against these formidable infectious maladies.

CAT: BRP-02035

CAS: 57944-13-5

Molecular Formula: C9H11FN2O5

Molecular Weight: 246.19

Purity: ≥95%

Appearance: Off-white Solid

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Storage: Store at -20 °C

Density: 1.63±0.1 g/cm3 (Predicted)

InChIKey: FVBOTRDLABQYMI-XVFCMESISA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)F)O

IUPAC Name: 1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H11FN2O5/c10-6-4(3-13)17-8(7(6)15)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s1

Synonyms: 3'-Fluoro-3'-deoxyuridine; 1-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)uracil; 1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoroguanosine

Description: N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoroguanosine, a biomedical compound, demonstrates its effectiveness in targeting and treating specific diseases. Its therapeutic potential and precise mechanism of action can be explored through the referenced websites, providing comprehensive information concerning drug interactions and its efficacy in addressing various medical conditions.

CAT: BRP-02037

CAS: 2080404-19-7

Molecular Formula: C35H36FN5O7

Molecular Weight: 657.69

Purity: ≥95%

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Density: 1.38±0.1 g/cm3

InChIKey: DHDSAIMYCCHNMS-UNVYQVKTSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)F)O

IUPAC Name: N-[9-[(2R,3S,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-fluoro-3-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C35H36FN5O7/c1-20(2)31(43)39-34-38-30-28(32(44)40-34)37-19-41(30)33-29(42)27(36)26(48-33)18-47-35(21-8-6-5-7-9-21,22-10-14-24(45-3)15-11-22)23-12-16-25(46-4)17-13-23/h5-17,19-20,26-27,29,33,42H,18H2,1-4H3,(H2,38,39,40,43,44)/t26-,27-,29-,33-/m1/s1

Synonyms: 5'-O-DMT-N2-isobutyryl-3'-Fluoro-3'-deoxyguanosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-deoxy-3'-fluoro-N-isobutyrylguanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-3'-fluoro-N-(2-methyl-1-oxopropyl)guanosine; N-(9-((2R,3S,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-3-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; 5'-O-DMT-N2-ibu-3'-F-3'-dG; 5'-O-DMT-3'-F-dG(iBu)

3'-Deoxy-3'-fluorocytidine

Description: 3'-Deoxy-3'-fluorocytidine is a purine nucleoside analogue. It is an antiviral agent.

CAT: BRP-02038

CAS: 123402-20-0

Molecular Formula: C9H12FN3O4

Molecular Weight: 245.21

Purity: ≥95%

Appearance: Off-white Solid

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5 mg	$298	In stock

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Storage: Store at 2-8 °C

Density: 1.82±0.1 g/cm3 (Predicted)

Melting Point: 221-223°C

Boiling Point: 500.1±60.0°C (Predicted)

InChIKey: PKOBNLOZXOHYOP-XVFCMESISA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)F)O

IUPAC Name: 4-amino-1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C9H12FN3O4/c10-6-4(3-14)17-8(7(6)15)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6-,7-,8-/m1/s1

Synonyms: Cytidine, 3-deoxy-3-fluoro-; 3'-Fluoro-3'-deoxycytidine; 1-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)thymine; 4-amino-1-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-3,4-dihydropyrimidin-2(1H)-one; 3'-F-3'-Dc

7-Methylguanosine (BRP-02122)

Description: 7-Methylguanosine is a modified form of the purine nucleotides. When present in human urine, it may be a biomarker for certain cancers.

CAT: BRP-02122

CAS: 20244-86-4

Molecular Formula: C11H16N5O5

Molecular Weight: 298.28

Purity: ≥95%

Appearance: White Powder

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100 mg	$299	In stock
1 g	$599	In stock

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Storage: Store at 2-8 °C

Melting Point: 165 °C

Symbol: m⁷G

InChIKey: OGHAROSJZRTIOK-KQYNXXCUSA-O

Solubility: Soluble in DMSO (Slightly), Water (Slightly)

CanonicalSMILES: CN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)CO)O)O

IUPAC Name: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-methyl-1H-purin-9-ium-6-one

InChI: InChI=1S/C11H15N5O5/c1-15-3-16(8-5(15)9(20)14-11(12)13-8)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2-,12,13,14,20)/p+1/t4-,6-,7-,10-/m1/s1

Synonyms: N7-Methylguanosine; 1H-Purinium, 2-amino-6,9-dihydroxy-7-methyl-6-oxo-9-b-D-ribofuranosyl-; Purinium, 2-amino-1,6,-dihydroxy-7-methyl-6-oxo-9-β-D-ribofuranosyl-; Guanosine, 7-Methyl-

Related CAS: 34080-10-9 (Deleted CAS)

5-Methoxycarbonylmethyl-2-thiouridine (BRP-02129)

Description: 5-(Methoxycarbonylmethyl)-2-thiouridine can be used as analyte in biological study for attomole quantification and global profile of RNA modifications in study of epitranscriptome of human neural stem cells. It can also be used to biological computational studies to provide insights into effects of modified ribonucleotides and Mg2+ on structures and stabilities of tRNAs. A trace nucleoside, isolated from yeast transfer RNA. A nucleoside in the anticodon at the wobble position of some Saccharomyces cerevisiae bacteria.

CAT: BRP-02129

CAS: 20299-15-4

Molecular Formula: C12H16N2O7S

Molecular Weight: 332.33

Purity: ≥95%

Appearance: White to Off-white Powder

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25 mg	$1150	In stock

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Storage: Store at RT

Density: 1.6±0.1 g/cm3

Melting Point: 195-197 °C

Symbol: mcm⁵s²U

InChIKey: HLZXTFWTDIBXDF-PNHWDRBUSA-N

CanonicalSMILES: COC(=O)CC1=CN(C(=S)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: methyl 2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-2-sulfanylidenepyrimidin-5-yl]acetate

InChI: InChI=1S/C12H16N2O7S/c1-20-7(16)2-5-3-14(12(22)13-10(5)19)11-9(18)8(17)6(4-15)21-11/h3,6,8-9,11,15,17-18H,2,4H2,1H3,(H,13,19,22)/t6-,8-,9-,11-/m1/s1

Synonyms: 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-4-oxo-1-β-D-ribofuranosyl-2-thioxo-, methyl ester; 5-(Methoxycarbonylmethyl)-2-thiouridine; 5-(2-methoxy-2-oxoethyl)-1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 5-(2-methoxy-2-oxoethyl)2-thiouridine

5-Methoxycarbonylmethyluridine (BRP-02131)

Description: 5-Methoxycarbonyl methyl uridine is a nucleoside constituent of yeast transfer RNA. 5-Methoxycarbonyl methyl uridine is also a derivative of 5-carboxymethyluridine, a carboxyl-containing nucleoside that was isolated from transfer RNA of Baker's Yeast.

CAT: BRP-02131

CAS: 29428-50-0

Molecular Formula: C12H16N2O8

Molecular Weight: 316.26

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at -20 °C

Density: 1.570±0.06 g/cm3 at 20°C, 760 Torr

Melting Point: 160-162 °C

Symbol: mcm⁵U

InChIKey: YIZYCHKPHCPKHZ-PNHWDRBUSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: COC(=O)CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: methyl 2-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]acetate

InChI: InChI=1S/C12H16N2O8/c1-21-7(16)2-5-3-14(12(20)13-10(5)19)11-9(18)8(17)6(4-15)22-11/h3,6,8-9,11,15,17-18H,2,4H2,1H3,(H,13,19,20)/t6-,8-,9-,11-/m1/s1

Synonyms: 5-(Methoxycarbonyl)methyluridine (MCM5U); Uridine 5-acetic acid methyl ester; 1,2,3,4-Tetrahydro-2,4-dioxo-1-beta-D-ribofuranosyl-5-pyrimidineacetic acid methyl ester; 5-(2-methoxy-2-oxoethyl)uridine; 5-Mcmu; Methyl 2-(1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetate

5-Methoxycarbonylmethyl-2'-O-methyluridine (BRP-02136)

Description: 5-Methoxycarbonylmethyl-2'-O-methyluridine, an indispensable biomedical compound, is extensively employed in the realm of research and development for antiviral drugs. This multifaceted compound assumes a paramount role in tackling diverse viral infections, meticulously targeting distinctive RNA viruses. Its eminent significance stems from its peculiar chemical structure which confers it with the potential to exhibit vigorous antiviral activity, hindering viral replication.

CAT: BRP-02136

CAS: 60197-31-1

Molecular Formula: C13H18N2O8

Molecular Weight: 330.29

Purity: ≥95%

Appearance: White to Off-white Solid

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5 mg	$599	In stock
20 mg	$990	In stock

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Storage: Store at 2-8 °C

Density: 1.50±0.1 g/cm3

Symbol: mcm⁵Um

InChIKey: XOTXNXXJZCFUOA-UGKPPGOTSA-N

CanonicalSMILES: COC1C(C(OC1N2C=C(C(=O)NC2=O)CC(=O)OC)CO)O

IUPAC Name: methyl 2-[1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]acetate

InChI: InChI=1S/C13H18N2O8/c1-21-8(17)3-6-4-15(13(20)14-11(6)19)12-10(22-2)9(18)7(5-16)23-12/h4,7,9-10,12,16,18H,3,5H2,1-2H3,(H,14,19,20)/t7-,9-,10-,12-/m1/s1

Synonyms: 5-(Methoxycarbonyl)methyl-2'-O-Methyl uridine; (2-OMe-MCM5U); 2'-O-Methyluridine 5-acetic acid methyl ester; 1,2,3,4-Tetrahydro-1-(2-O-methyl-beta-D-ribofuranosyl)-2,4-dioxo-5-pyrimidineacetic acid methyl ester; 5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-1-(2-O-methyl-b-D-ribofuranosyl)-2,4-dioxo-, methyl ester; Methyl 2-(1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetate

1-Methyladenosine (BRP-02149)

Description: 1-Methyladenosine is a modified nucleoside often found in tRNAs and rRNA. In the biomedical industry, it is pivotal for protein synthesis, cellular function, and responses to stressors. It's also being studied concerning viral RNA methylation in diseases such as hepatitis C.

CAT: BRP-02149

CAS: 15763-06-1

Molecular Formula: C11H15N5O4

Molecular Weight: 281.27

Purity: ≥95%

Appearance: White to Off-white Crystalline Powder

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Storage: Store at -20 °C, under inert atmosphere

Density: 1.88±0.1 g/cm3

Melting Point: >217 °C (dec.)

Boiling Point: 655.4±65.0 °C at 760 mmHg

Symbol: m¹A

InChIKey: GFYLSDSUCHVORB-IOSLPCCCSA-N

Solubility: Soluble in DMSO (Slightly), Water (Slightly, Sonicated)

CanonicalSMILES: CN1C=NC2=C(C1=N)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methylpurin-9-yl)oxolane-3,4-diol

InChI: InChI=1S/C11H15N5O4/c1-15-3-14-10-6(9(15)12)13-4-16(10)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11-12,17-19H,2H2,1H3/t5-,7-,8-,11-/m1/s1

Synonyms: Adenosine, 1-methyl-; N1-Methyladenosine; N1-Methyl-D-adenosine; NSC 92165; (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)tetrahydrofuran-3,4-diol; Adenosine, N,6-didehydro-1,9-dihydro-1-methyl-

2'-O-Methylguanosine

Description: It is a guanine nucleoside analogue that is used to prepare nucleoside derivatives as inhibitors of RNA-dependent RNA virus polymerases.

CAT: BRP-00011

CAS: 2140-71-8

Molecular Formula: C11H15N5O5

Molecular Weight: 297.27

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at 2-8°C

Density: 1.98±0.1 g/cm3 (Predicted)

Melting Point: >216°C (dec.)

Boiling Point: 711.7°C at 760 mmHg

Symbol: Gm

InChIKey: OVYNGSFVYRPRCG-KQYNXXCUSA-N

Solubility: Soluble in Aqueous Base (Slightly), DMSO (Slightly)

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)CO)O

IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C11H15N5O5/c1-20-7-6(18)4(2-17)21-10(7)16-3-13-5-8(16)14-11(12)15-9(5)19/h3-4,6-7,10,17-18H,2H2,1H3,(H3,12,14,15,19)/t4-,6-,7-,10-/m1/s1

Synonyms: 2'-(O-Methyl) Guanosine; Guanosine, 2'-O-methyl-; 2'-O-Methyl Guanosine; O2'-Methylguanosine; 2-amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-amino-9-(2-O-methyl-beta-D-ribofuranosyl)-1,9-dihydro-6H-purin-6-one