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Phosphoramidites

2'-Modified Phosphoramidites
(529/529)
2'-Phosphoramidites
(27/27)
3'-Modified Phosphoramidites
(201/201)
5'-Modified Phosphoramidites
(30/30)
Arabino Phosphoramidites
(23/23)
Base Protected Phosphoramidites (418/418) Dye Phosphoramidites
(53/53)
Label Phosphoramidites
(80/80)
Linker Phosphoramidites
(85/85)
Other Phosphoramidites
(97/97)
PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12)
Reverse Phosphoramidites
(25/25)
Spacer Phosphoramidites
(24/24)
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[5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-U](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-U](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite] is a complex modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of three sequentially linked nucleosides: a 5'-O-DMTr-2'-OMe-uridine (U), a second 2'-OMe-uridine, and a third 2'-OMe-uridine. Each linkage is protected by a cyanoethyl (CE) group, ensuring stability during synthesis. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making them valuable for advanced biochemical research and therapeutic applications.
CAT: BRP-01188
Molecular Formula: C66H81N10O25P3
Molecular Weight: 1507.34
Purity: ≥90% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: RVLLLKZWUNUMEY-BNMQGBNESA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C66H81N10O25P3/c1-41(2)76(42(3)4)102(91-35-13-29-67)99-54-49(97-60(57(54)87-7)73-32-26-51(77)70-63(73)80)39-94-103(83,92-36-14-30-68)101-56-50(98-62(59(56)89-9)75-34-28-53(79)72-65(75)82)40-95-104(84,93-37-15-31-69)100-55-48(96-61(58(55)88-8)74-33-27-52(78)71-64(74)81)38-90-66(43-16-11-10-12-17-43,44-18-22-46(85-5)23-19-44)45-20-24-47(86-6)25-21-45/h10-12,16-28,32-34,41-42,48-50,54-62H,13-15,35-40H2,1-9H3,(H,70,77,80)(H,71,78,81)(H,72,79,82)/t48-,49-,50-,54-,55-,56-,57-,58-,59-,60-,61-,62-,102?,103?,104?/m1/s1
Synonyms: mU[5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-U](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]mU-mU

PMO-CAG trimer phosphoramidochloridate

Description: PMO-CAG trimer phosphoramidochloridate is a chemically modified oligonucleotide used in molecular biology and therapeutic applications. It consists of a trimer sequence (Cytosine-Adenine-Guanine, CAG) within a phosphorodiamidate morpholino oligomer (PMO) backbone. The phosphoramidate group is modified with a chloridate moiety, which aids in coupling the trimer to other molecular structures or sequences during synthesis. This configuration enhances the stability, binding affinity, and resistance to nucleases, making it a valuable tool for gene modulation, antisense therapies, and other nucleic acid-based applications.
CAT: BRP-01189
Molecular Formula: C80H90ClN20O16P3
Molecular Weight: 1716.10
Purity: ≥90% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: NCZHWRORJFEAOK-UTKGGJPZSA-N
IUPAC Name: ((2S,6R)-6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-((((2S,6R)-6-(6-benzamido-9H-purin-9-yl)-4-((dimethylamino)(((2S,6R)-6-(2-isobutyramido-6-(4-nitrophenethoxy)-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methoxy)phosphoryl)morpholin-2-yl)methoxy)(dimethylamino)phosphoryl)morpholin-2-yl)methyl dimethylphosphoramidochloridate
InChI: InChI=1S/C80H90ClN20O16P3/c1-54(2)74(102)90-78-89-73-70(77(91-78)111-41-39-55-34-36-61(37-35-55)101(106)107)85-53-100(73)66-45-95(80(58-28-18-11-19-29-58,59-30-20-12-21-31-59)60-32-22-13-23-33-60)42-62(115-66)49-113-120(110,94(7)8)97-44-64(117-68(47-97)99-52-84-69-71(82-51-83-72(69)99)88-76(104)57-26-16-10-17-27-57)50-114-119(109,93(5)6)96-43-63(48-112-118(81,108)92(3)4)116-67(46-96)98-40-38-65(87-79(98)105)86-75(103)56-24-14-9-15-25-56/h9-38,40,51-54,62-64,66-68H,39,41-50H2,1-8H3,(H,82,83,88,104)(H,86,87,103,105)(H,89,90,91,102)/t62-,63-,64-,66+,67+,68+,118?,119?,120?/m0/s1
Synonyms: PMO-C(Ac)A(Bz)G(iBu) trimer phosphoramidochloridate

[5'-O-DMTr-2'-F-dC(Ac)](pCyEt)[2'-OMe-U](pCyEt)[2'-F-dG(iBu)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-F-dC(Ac)](pCyEt)[2'-OMe-U](pCyEt)[2'-F-dG(iBu)-3'-CE-Phosphoramidite] is a complex modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of three sequentially linked nucleosides: a 5'-O-DMTr-2'-fluoro-deoxycytidine (2'-F-dC) with an acetyl (Ac) protecting group, a 2'-O-methyl-uridine (2'-OMe-U), and a 2'-fluoro-deoxyguanosine (2'-F-dG) with an isobutyryl (iBu) protecting group. Each linkage is protected by a cyanoethyl (CE) group, ensuring stability during synthesis. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making them valuable for advanced biochemical research and therapeutic applications.
CAT: BRP-01190
Molecular Formula: C71H85F2N14O23P3
Molecular Weight: 1633.45
Purity: ≥92% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: LFFQMQJBVLQFPU-VKWGPYKVSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-fluoro-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C71H85F2N14O23P3/c1-41(2)63(90)82-68-81-62-57(64(91)83-68)77-40-86(62)66-55(72)58(108-111(100-34-14-29-74)87(42(3)4)43(5)6)51(106-66)38-103-113(95,102-36-16-31-76)110-60-52(107-67(61(60)98-10)85-33-28-54(89)80-70(85)93)39-104-112(94,101-35-15-30-75)109-59-50(105-65(56(59)73)84-32-27-53(78-44(7)88)79-69(84)92)37-99-71(45-17-12-11-13-18-45,46-19-23-48(96-8)24-20-46)47-21-25-49(97-9)26-22-47/h11-13,17-28,32-33,40-43,50-52,55-56,58-61,65-67H,14-16,34-39H2,1-10H3,(H,80,89,93)(H,78,79,88,92)(H2,81,82,83,90,91)/t50-,51-,52-,55-,56-,58-,59-,60-,61-,65-,66-,67-,111?,112?,113?/m1/s1

mU[5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-G(iBu)](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]-mG-Mu

Description: mU[5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-G(iBu)](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]-mG-Mu is a complex modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of three sequentially linked nucleosides: a 5'-O-DMTr-2'-O-methyl-uridine (2'-OMe-U), a 2'-O-methyl-guanosine (2'-OMe-G) with an isobutyryl (iBu) protecting group, and another 2'-O-methyl-uridine (2'-OMe-U). Each linkage is protected by a cyanoethyl (CE) group, ensuring stability during synthesis. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making them valuable for advanced biochemical research and therapeutic applications.
CAT: BRP-01191
Molecular Formula: C71H88N13O25P3
Molecular Weight: 1616.47
Purity: ≥90% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: LHSQAKDMIMJKFU-FSOKJIOASA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C71H88N13O25P3/c1-42(2)63(87)79-68-78-62-55(64(88)80-68)75-41-83(62)67-61(97-11)58(109-111(91,100-36-16-31-73)102-39-51-56(107-110(99-35-15-30-72)84(43(3)4)44(5)6)59(95-9)65(105-51)81-33-28-53(85)76-69(81)89)52(106-67)40-103-112(92,101-37-17-32-74)108-57-50(104-66(60(57)96-10)82-34-29-54(86)77-70(82)90)38-98-71(45-18-13-12-14-19-45,46-20-24-48(93-7)25-21-46)47-22-26-49(94-8)27-23-47/h12-14,18-29,33-34,41-44,50-52,56-61,65-67H,15-17,35-40H2,1-11H3,(H,76,85,89)(H,77,86,90)(H2,78,79,80,87,88)/t50-,51-,52-,56-,57-,58-,59-,60-,61-,65-,66-,67-,110?,111?,112?/m1/s1
Synonyms: [5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-G(iBu)](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]; UmGmUm

[5'-O-DMTr-2'-OMe-C(Ac)](P-thio-pCyEt)[2'-OMe-U](P-thio-pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-C(Ac)](P-thio-pCyEt)[2'-OMe-U](P-thio-pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite] is a complex modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of three sequentially linked nucleosides: a 5'-O-DMTr-2'-O-methyl-cytidine (2'-OMe-C) with an acetyl (Ac) protecting group, a 2'-O-methyl-uridine (2'-OMe-U), and a 2'-O-methyl-adenosine (2'-OMe-A) with a benzoyl (Bz) protecting group. Each linkage is protected by a phosphorothioate (P-thio) group and a cyanoethyl (CE) group, ensuring stability during synthesis. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making them valuable for advanced biochemical research and therapeutic applications.
CAT: BRP-01192
Molecular Formula: C76H89N14O22P3S2
Molecular Weight: 1707.67
Purity: ≥90% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: YRUITVGNVXNUNZ-QPPMCZIUSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphorothioyl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphorothioyl)oxy)methyl)-5-(6-benzamido-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C76H89N14O22P3S2/c1-47(2)90(48(3)4)113(102-39-17-34-77)110-62-57(108-73(65(62)98-8)89-46-82-61-68(80-45-81-69(61)89)86-70(93)50-20-13-11-14-21-50)43-105-114(116,103-40-18-35-78)112-64-58(109-72(67(64)100-10)88-38-33-60(92)85-75(88)95)44-106-115(117,104-41-19-36-79)111-63-56(107-71(66(63)99-9)87-37-32-59(83-49(5)91)84-74(87)94)42-101-76(51-22-15-12-16-23-51,52-24-28-54(96-6)29-25-52)53-26-30-55(97-7)31-27-53/h11-16,20-33,37-38,45-48,56-58,62-67,71-73H,17-19,39-44H2,1-10H3,(H,85,92,95)(H,80,81,86,93)(H,83,84,91,94)/t56-,57-,58-,62-,63-,64-,65-,66-,67-,71-,72-,73-,113?,114?,115?/m1/s1
Synonyms: mC[5'-O-DMTr-2'-OMe-C(Ac)](P-thio-pCyEt)[2'-OMe-U](P-thio-pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite]mU-mA

[5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-G(iBu)](pCyEt)[2'-OMe-C(Ac)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-G(iBu)](pCyEt)[2'-OMe-C(Ac)-3'-CE-Phosphoramidite] is a complex modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of three sequentially linked nucleosides: a 5'-O-DMTr-2'-O-methyl-uridine (2'-OMe-U), a 2'-O-methyl-guanosine (2'-OMe-G) with an isobutyryl (iBu) protecting group, and a 2'-O-methyl-cytidine (2'-OMe-C) with an acetyl (Ac) protecting group. Each linkage is protected by a cyanoethyl (CE) group, ensuring stability during synthesis. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making them valuable for advanced biochemical research and therapeutic applications.
CAT: BRP-01193
Molecular Formula: C73H91N14O25P3
Molecular Weight: 1657.53
Purity: ≥90% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: CTRIMGUISJCSNZ-VILHZJDJSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((((((2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C73H91N14O25P3/c1-43(2)65(90)82-70-81-64-57(66(91)83-70)77-42-86(64)69-63(100-12)60(112-114(94,103-37-17-32-75)105-40-53-58(110-113(102-36-16-31-74)87(44(3)4)45(5)6)61(98-10)67(108-53)84-34-29-55(78-46(7)88)79-71(84)92)54(109-69)41-106-115(95,104-38-18-33-76)111-59-52(107-68(62(59)99-11)85-35-30-56(89)80-72(85)93)39-101-73(47-19-14-13-15-20-47,48-21-25-50(96-8)26-22-48)49-23-27-51(97-9)28-24-49/h13-15,19-30,34-35,42-45,52-54,58-63,67-69H,16-18,36-41H2,1-12H3,(H,80,89,93)(H,78,79,88,92)(H2,81,82,83,90,91)/t52-,53-,54-,58-,59-,60-,61-,62-,63-,67-,68-,69-,113?,114?,115?/m1/s1
Synonyms: mU[5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-G(iBu)](pCyEt)[2'-OMe-C(Ac)-3'-CE-Phosphoramidite]mG-mC

[5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-OMe-A(Bz)](pCyEt)[2'-OMe-C(Ac)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-OMe-A(Bz)](pCyEt)[2'-OMe-C(Ac)-3'-CE-Phosphoramidite] is a complex modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of three sequentially linked nucleosides: a 5'-O-DMTr-2'-O-methyl-guanosine (2'-OMe-G) with an isobutyryl (iBu) protecting group, a 2'-O-methyl-adenosine (2'-OMe-A) with a benzoyl (Bz) protecting group, and a 2'-O-methyl-cytidine (2'-OMe-C) with an acetyl (Ac) protecting group. Each linkage is protected by a cyanoethyl (CE) group, ensuring stability during synthesis. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making them valuable for advanced biochemical research and therapeutic applications.
CAT: BRP-01194
Molecular Formula: C81H96N17O24P3
Molecular Weight: 1784.68
Purity: ≥90% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: OTKBGJKLKVYCOV-FEONMEANSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C81H96N17O24P3/c1-48(2)73(100)93-79-92-72-63(75(102)94-79)88-47-97(72)78-68(109-11)65(58(117-78)42-111-81(53-24-17-14-18-25-53,54-26-30-56(106-8)31-27-54)55-28-32-57(107-9)33-29-55)121-125(105,114-41-21-37-84)116-44-60-66(69(110-12)77(119-60)96-46-87-62-70(85-45-86-71(62)96)91-74(101)52-22-15-13-16-23-52)122-124(104,113-40-20-36-83)115-43-59-64(120-123(112-39-19-35-82)98(49(3)4)50(5)6)67(108-10)76(118-59)95-38-34-61(89-51(7)99)90-80(95)103/h13-18,22-34,38,45-50,58-60,64-69,76-78H,19-21,39-44H2,1-12H3,(H,85,86,91,101)(H,89,90,99,103)(H2,92,93,94,100,102)/t58-,59-,60-,64-,65-,66-,67-,68-,69-,76-,77-,78-,123?,124?,125?/m1/s1
Synonyms: mG[5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-OMe-A(Bz)](pCyEt)[2'-OMe-C(Ac)-3'-CE-Phosphoramidite]mA-mC

TFA-Aminobutyl-1-3-propanediol-DMT succinate, TEA salt

Description: TFA-Aminobutyl-1-3-propanediol-DMT succinate, TEA salt, is a synthetic intermediate or compound used in organic chemistry and biochemical research. It features a trifluoroacetyl (TFA) group, an aminobutyl-1,3-propanediol moiety, and a dimethoxytrityl (DMT) protection group linked to a succinate modification. This compound is utilized in solid-phase synthesis of molecules and potentially in drug discovery processes where chemical modifications and protection groups are essential for the development and manipulation of organic molecules.
CAT: BRP-01241
Molecular Formula: C34H38F3NO8 (free acid)
Molecular Weight: 645.67 (free acid)
Purity: ≥98% by UPLC
Appearance: Colorless to yellow oily matter
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Storage: Store at -20 °C
IUPAC Name: 4-((2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-6-(2,2,2-trifluoroacetamido)hexyl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine
Synonyms: Trifluoroacetatyl-Aminobutyl-1-3-Propanediol-DMT Succinate, TEA salt

3-O-DMT-2,2-(dicarboxymethylamido)propyl-1-O-succinate, TEA salt

Description: 3-O-DMT-2,2-(dicarboxymethylamido)propyl-1-O-succinate, TEA salt is a chemical compound stabilized with triethylamine (TEA) salt. This compound is likely used in organic synthesis as an intermediate or precursor for the modification of biomolecules or organic compounds, particularly in solid-phase synthesis or other chemical reactions requiring stable protection groups and functional groups for further manipulation.
CAT: BRP-01242
Molecular Formula: C32H36N2O9 (free acid)
Molecular Weight: 592.65 (free acid)
Purity: ≥97% by HPLC
Appearance: White, off-white to light yellow powder
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Storage: Store at -20 °C, in tightly closed containers, protected from humidity
IUPAC Name: 4-(2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(methylamino)-2-(methylcarbamoyl)-3-oxopropoxy)-4-oxobutanoic acid;N,N-diethylethanamine
Synonyms: 3-(4,4'-dimethoxytrityloxy)-2,2-(dicarboxymethylamido)propyl-1-O-succinate, triethylamine salt

Cholesteryl succinate, TEA salt (plant source)

Description: Cholesteryl succinate, TEA salt (plant source), refers to a compound derived from plants that combines cholesteryl (a cholesterol derivative) with succinic acid, forming a salt stabilized with triethylamine (TEA). This compound is utilized in various biochemical and pharmaceutical applications, particularly in lipid research and drug delivery systems. Cholesteryl derivatives are known for their ability to interact with lipid membranes and cellular structures, making them valuable in studies involving liposomes, lipid-based nanoparticles, and drug formulation.
CAT: BRP-01243
Molecular Formula: C61H86O9 (free acid)
Molecular Weight: 963.35 (free acid)
Purity: ≥98% by HPLC
Appearance: Colorless to faint yellow oily matter
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Storage: Store at -20 °C
IUPAC Name: 4-((1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-((6-(((3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)hexyl)oxy)propan-2-yl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine
Synonyms: 1-(4,4'-Dimethoxytrityloxy)-3-(6-(Cholest-5-en-3β-oxy)hexyloxy) propan-2-succinate, triethylamine salt (plant source)

3'-Thio modifier 6 S-S-DMTr-linker-succinate, TEA salt

Description: 3'-Thio modifier 6 S-S-DMTr-linker-succinate, TEA salt, is a specialized chemical compound used in nucleic acid synthesis and modification. The salt form is stabilized with triethylamine (TEA), enhancing its stability and solubility in aqueous solutions commonly used in biochemical research. This compound is crucial in nucleoside chemistry for introducing modifications at the 3' end of nucleic acids, which can alter their stability, interaction properties, or enzymatic resistance. Such modifications are valuable in studies aiming to understand RNA or DNA structure-function relationships, in nucleic acid-based technologies, and in the development of therapeutic oligonucleotides.
CAT: BRP-01244
Molecular Formula: C35H44O9S2 (free acid)
Molecular Weight: 672.85 (free acid)
Purity: ≥98% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
IUPAC Name: 4-[2-[3-[3-[2-[bis(4-methoxyphenyl)-phenylmethoxy]ethoxy]propyldisulfanyl]propoxy]ethoxy]-4-oxobutanoic acid;N,N-diethylethanamine
Synonyms: 1-O-Dimethoxytrityl-3-oxahexyl-disulfide 1'-succinate, triethylamine salt; 1,1-bis(4-methoxyphenyl)-18-oxo-1-phenyl-2,5,14,17-tetraoxa-9,10-dithiahenicosan-21-oic acid, triethylamine salt

Cholesteryl-TEG-succinate (plant source)

Description: Cholesteryl-TEG-succinate (plant source) is a compound derived from plants that combines cholesteryl (a derivative of cholesterol) with succinic acid, incorporating a tetraethylene glycol (TEG) linker. This structure is designed to enhance the solubility and stability of cholesteryl in aqueous solutions, making it suitable for various applications in biochemical and pharmaceutical research. In biochemical studies, cholesteryl derivatives are utilized to investigate lipid-protein interactions, lipid-based drug delivery systems, and the formation of liposomes. The addition of a TEG linker further improves the compound's solubility and allows for conjugation with other molecules or attachment to surfaces, potentially facilitating its use in drug delivery vehicles or biomaterials.
CAT: BRP-01245
CAS: 873435-28-0
Molecular Formula: C65H93NO13
Molecular Weight: 1096.45
Purity: ≥98% by HPLC
Appearance: Colorless to faint yellow oily matter
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Storage: Store at -20 °C
InChIKey: YSSIXSBUMAIUOE-MFCMZYHHSA-N
IUPAC Name: 17-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-1-(((3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-1,19-dioxo-6,9,12,15,18-pentaoxa-2-azadocosan-22-oic acid
InChI: InChI=1S/C65H93NO13/c1-46(2)13-11-14-47(3)57-27-28-58-56-26-21-51-43-54(31-33-63(51,4)59(56)32-34-64(57,58)5)79-62(70)66-35-12-36-73-37-38-74-39-40-75-41-42-76-44-55(78-61(69)30-29-60(67)68)45-77-65(48-15-9-8-10-16-48,49-17-22-52(71-6)23-18-49)50-19-24-53(72-7)25-20-50/h8-10,15-25,46-47,54-59H,11-14,26-45H2,1-7H3,(H,66,70)(H,67,68)/t47-,54+,55?,56+,57-,58+,59+,63+,64-/m1/s1
Synonyms: Cholest-5-en-3-ol (3β)-, 3-(22-hydrogen 17-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-19-oxo-6,9,12,15,18-pentaoxa-2-azadocosanedioate)

2',3'-Diacetyl Guanosine (n-ibu) CED phosphoramidite

Description: 2',3'-Diacetyl Guanosine (n-ibu) CED phosphoramidite is a chemically modified guanosine nucleotide used in oligonucleotide synthesis. Featuring acetyl groups at the 2' and 3' positions and a CED (cyanoethyl diisopropylamino) phosphoramidite group, it facilitates the creation of stable, high-fidelity DNA and RNA sequences for advanced genetic research and biotechnological applications.
CAT: BRP-01255
CAS: 1350450-67-7
Molecular Formula: C27H40N7O9P
Molecular Weight: 637.63
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InChIKey: IGPBVQCAEJGBML-KIDUIKHZSA-N
CanonicalSMILES: N#CCCOP(OCC1OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C(OC(=O)C)C1OC(=O)C)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-2-((((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
InChI: InChI=1S/C27H40N7O9P/c1-14(2)24(37)31-27-30-23-20(25(38)32-27)29-13-33(23)26-22(42-18(8)36)21(41-17(7)35)19(43-26)12-40-44(39-11-9-10-28)34(15(3)4)16(5)6/h13-16,19,21-22,26H,9,11-12H2,1-8H3,(H2,30,31,32,37,38)/t19-,21-,22-,26-,44?/m1/s1
Synonyms: Guanosine, N-(2-methyl-1-oxopropyl)-, 2',3'-diacetate 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

2',3'-Diacetyl Uridine CED phosphoramidite

Description: 2',3'-Diacetyl Uridine CED phosphoramidite is a modified uridine nucleotide used in the synthesis of RNA and DNA oligonucleotides. It has acetyl groups at the 2' and 3' positions and a CED (cyanoethyl diisopropylamino) phosphoramidite group, enabling the production of stable and high-fidelity nucleic acid sequences for genetic research and biotechnological applications.
CAT: BRP-01256
CAS: 208655-84-9
Molecular Formula: C22H33N4O9P
Molecular Weight: 528.49
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InChIKey: QUNYGIBAHMVXKK-UZKKNRNZSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC1C(C(C(O1)N2C=CC(=O)NC2=O)OC(=O)C)OC(=O)C
IUPAC Name: [(2R,3R,4R,5R)-4-acetyloxy-2-[[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxymethyl]-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl] acetate
InChI: InChI=1S/C22H33N4O9P/c1-13(2)26(14(3)4)36(31-11-7-9-23)32-12-17-19(33-15(5)27)20(34-16(6)28)21(35-17)25-10-8-18(29)24-22(25)30/h8,10,13-14,17,19-21H,7,11-12H2,1-6H3,(H,24,29,30)/t17-,19-,20-,21-,36?/m1/s1
Synonyms: Uridine, 2',3'-diacetate 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Uridine, 2',3'-diacetate 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-2-((((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate

2'-O-butyne Uridine CED phosphoramidite

Description: 2'-O-butyne Uridine CED phosphoramidite is a chemical compound used in oligonucleotide synthesis. It is a derivative of uridine, where the 2' position of the ribose sugar is modified with a butyne group (-C≡C-) and is functionalized with a CED (2-cyanoethyl diisopropylphosphoramidite) moiety. This modification allows for the selective incorporation of the modified uridine into the growing nucleotide chain during solid-phase synthesis of oligonucleotides. The presence of the butyne group enables further chemical reactions for the conjugation of various functional groups or molecules. This compound plays a crucial role in the design and synthesis of specialized oligonucleotides for applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-01258
CAS: 2305570-48-1
Molecular Formula: C43H51N4O9P
Molecular Weight: 798.86
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InChIKey: IZIBOIGAGRJZFP-QBLJBMGASA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=CC(=O)NC2=O)C1OCC#CC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(but-2-yn-1-yloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C43H51N4O9P/c1-8-9-27-52-40-39(56-57(54-28-13-25-44)47(30(2)3)31(4)5)37(55-41(40)46-26-24-38(48)45-42(46)49)29-53-43(32-14-11-10-12-15-32,33-16-20-35(50-6)21-17-33)34-18-22-36(51-7)23-19-34/h10-12,14-24,26,30-31,37,39-41H,13,27-29H2,1-7H3,(H,45,48,49)/t37-,39-,40-,41-,57?/m1/s1
Synonyms: 5'-O-DMTr-2'-O-butyne-U-3'-CE-Phosphoramidite

2'-O-butyne Adenosine (n-bz) CED phosphoramidite

Description: 2'-O-butyne Adenosine (n-bz) CED phosphoramidite is a specialized compound used in oligonucleotide synthesis. It consists of an adenosine nucleoside with a modification at the 2' position of the ribose sugar, where a butyne (-C≡C-) group is attached. Additionally, it features a benzoyl (n-bz) group to protect the amino group at the N6 position of adenine and a CED (2-cyanoethyl diisopropylphosphoramidite) moiety. This modification enables the selective incorporation of the modified adenosine into the growing nucleotide chain during solid-phase synthesis of oligonucleotides. The presence of the butyne group allows for further functionalization or conjugation, making it useful for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-01259
Molecular Formula: C51H56N7O8P
Molecular Weight: 926.01
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InChIKey: FNMMYMFLDRVDOX-LTMMGAFGSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(but-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C51H56N7O8P/c1-8-9-30-62-46-45(66-67(64-31-16-29-52)58(35(2)3)36(4)5)43(65-50(46)57-34-55-44-47(53-33-54-48(44)57)56-49(59)37-17-12-10-13-18-37)32-63-51(38-19-14-11-15-20-38,39-21-25-41(60-6)26-22-39)40-23-27-42(61-7)28-24-40/h10-15,17-28,33-36,43,45-46,50H,16,30-32H2,1-7H3,(H,53,54,56,59)/t43-,45-,46-,50-,67?/m1/s1
Synonyms: 5'-O-DMTr-2'-O-butyne-A(Bz)-3'-CE-Phosphoramidite

2'-O-butyne Guanosine (n-ibu) CED phosphoramidite

Description: 2'-O-butyne Guanosine (n-ibu) CED phosphoramidite is a specialized compound utilized in oligonucleotide synthesis. It consists of a guanosine nucleoside with a modification at the 2' position of the ribose sugar, where a butyne (-C≡C-) group is attached. Additionally, it features an isobutyryl (n-ibu) group to protect the amino group at the N2 position of guanine and a CED (2-cyanoethyl diisopropylphosphoramidite) moiety. This modification allows for the selective incorporation of the modified guanosine into the growing nucleotide chain during solid-phase synthesis of oligonucleotides. The presence of the butyne group enables further functionalization or conjugation, making it valuable for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-01260
Molecular Formula: C48H58N7O9P
Molecular Weight: 907.99
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InChIKey: ABJZHECXWHOPKB-VKFKYRIUSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(but-2-yn-1-yloxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C48H58N7O9P/c1-10-11-27-60-42-41(64-65(62-28-15-26-49)55(32(4)5)33(6)7)39(63-46(42)54-30-50-40-43(54)51-47(53-45(40)57)52-44(56)31(2)3)29-61-48(34-16-13-12-14-17-34,35-18-22-37(58-8)23-19-35)36-20-24-38(59-9)25-21-36/h12-14,16-25,30-33,39,41-42,46H,15,27-29H2,1-9H3,(H2,51,52,53,56,57)/t39-,41-,42-,46-,65?/m1/s1
Synonyms: 5'-O-DMTr-2'-O-butyne-G(iBu)-3'-CE-Phosphoramidite

2'-O-butyne Cytidine (n-bz) CED phosphoramidite

Description: 2'-O-butyne Cytidine (n-bz) CED phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It consists of a cytidine nucleoside modified with a 2'-O-butyne group and protected with a benzoyl (n-bz) group. Additionally, it contains a CED (2-cyanoethyl diisopropylphosphoramidite) moiety, which serves as a protecting group during the synthesis process. This phosphoramidite derivative allows for efficient and selective incorporation of the modified cytidine into the growing nucleotide chain during solid-phase synthesis. The presence of the butyne group enables further chemical reactions for the conjugation of various functional groups or molecules. This compound plays a crucial role in the design and synthesis of specialized oligonucleotides for applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-01265
Molecular Formula: C50H56N5O9P
Molecular Weight: 901.98
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InChIKey: ZCJRISCCQSIUEK-BZESDKEVSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(but-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C50H56N5O9P/c1-8-9-32-60-46-45(64-65(62-33-16-30-51)55(35(2)3)36(4)5)43(63-48(46)54-31-29-44(53-49(54)57)52-47(56)37-17-12-10-13-18-37)34-61-50(38-19-14-11-15-20-38,39-21-25-41(58-6)26-22-39)40-23-27-42(59-7)28-24-40/h10-15,17-29,31,35-36,43,45-46,48H,16,32-34H2,1-7H3,(H,52,53,56,57)/t43-,45-,46-,48-,65?/m1/s1
Synonyms: 5'-O-DMTr-2'-O-butyne-C(Bz)-3'-CE-Phosphoramidite

2'-O-Methyl Guanosine (n-PAC) CED phosphoramidite

Description: 2'-O-Methyl Guanosine (n-PAC) CED phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It consists of a guanosine nucleoside modified with a 2'-O-Methyl group and protected with a PAC (phenoxyacetyl) group. Additionally, it contains a CED (2-cyanoethyl diisopropylphosphoramidite) moiety, which serves as a protecting group during the synthesis process. This phosphoramidite derivative allows for efficient and selective incorporation of the modified guanosine into the growing nucleotide chain during solid-phase synthesis. The presence of the 2'-O-Methyl group provides stability and can influence the properties of the resulting oligonucleotide. This compound is essential in the design and synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-01267
CAS: 138906-79-3
Molecular Formula: C49H56N7O10P
Molecular Weight: 933.96
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InChIKey: FBLBODSDYPHQTB-KPWHVHSNSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(NC(=O)COC=4C=CC=CC4)NC32)C1OC)COC(C=5C=CC=CC5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxy-5-(6-oxo-2-(2-phenoxyacetamido)-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C49H56N7O10P/c1-32(2)56(33(3)4)67(64-28-14-27-50)66-43-40(29-63-49(34-15-10-8-11-16-34,35-19-23-37(59-5)24-20-35)36-21-25-38(60-6)26-22-36)65-47(44(43)61-7)55-31-51-42-45(55)53-48(54-46(42)58)52-41(57)30-62-39-17-12-9-13-18-39/h8-13,15-26,31-33,40,43-44,47H,14,28-30H2,1-7H3,(H2,52,53,54,57,58)/t40-,43-,44-,47-,67?/m1/s1
Synonyms: 5'-O-DMTr-2'-O-Methyl-G(Pac)-3'-CE-Phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(phenoxyacetyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

MMT-2'-O-Methyl Adenosine (n-bz) CED phosphoramidite

Description: MMT-2'-O-Methyl Adenosine (n-bz) CED phosphoramidite is a specialized reagent used in oligonucleotide synthesis. It consists of an adenosine nucleoside modified with a 2'-O-Methyl group and protected with a benzoyl (n-bz) group. Additionally, it contains a CED (2-cyanoethyl diisopropylphosphoramidite) moiety, which serves as a protecting group during the synthesis process. The MMT (Monomethoxytrityl) group is typically used for temporary protection of hydroxyl groups in nucleosides. This phosphoramidite derivative allows for efficient and selective incorporation of the modified adenosine into the growing nucleotide chain during solid-phase synthesis. This compound is crucial in the design and synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-01270
CAS: 2645354-88-5
Molecular Formula: C47H52N7O7P
Molecular Weight: 857.93
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InChIKey: GBMKDKSAHVWHSY-JIUDHRTHSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=NC=NC32)NC(=O)C=4C=CC=CC4)C1OC)COC(C=5C=CC=CC5)(C=6C=CC=CC6)C7=CC=C(OC)C=C7)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-methoxy-2-(((4-methoxyphenyl)diphenylmethoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C47H52N7O7P/c1-32(2)54(33(3)4)62(59-28-16-27-48)61-41-39(29-58-47(35-19-12-8-13-20-35,36-21-14-9-15-22-36)37-23-25-38(56-5)26-24-37)60-46(42(41)57-6)53-31-51-40-43(49-30-50-44(40)53)52-45(55)34-17-10-7-11-18-34/h7-15,17-26,30-33,39,41-42,46H,16,28-29H2,1-6H3,(H,49,50,52,55)/t39-,41-,42-,46-,62?/m1/s1
Synonyms: 5'-O-MMTr-2'-O-Methyl-A(Bz)-3'-CE-Phosphoramidite
* Only for research. Not suitable for any diagnostic or therapeutic use.

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