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Phosphoramidites

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2'-Modified Phosphoramidites
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[5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-guanosine with an isobutyryl (iBu) protecting group, coupled with a 2'-O-Me-adenosine featuring a benzoyl (Bz) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01148
Molecular Formula: C66H77N13O16P2
Molecular Weight: 1370.36
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: VTDGJORSPBHICB-LLYQIHFBSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C66H77N13O16P2/c1-40(2)60(80)75-65-74-59-52(62(82)76-65)72-39-78(59)64-56(87-10)54(49(92-64)35-88-66(44-21-15-12-16-22-44,45-23-27-47(84-7)28-24-45)46-25-29-48(85-8)30-26-46)95-97(83,90-34-18-32-68)91-36-50-53(94-96(89-33-17-31-67)79(41(3)4)42(5)6)55(86-9)63(93-50)77-38-71-51-57(69-37-70-58(51)77)73-61(81)43-19-13-11-14-20-43/h11-16,19-30,37-42,49-50,53-56,63-64H,17-18,33-36H2,1-10H3,(H,69,70,73,81)(H2,74,75,76,80,82)/t49-,50-,53-,54-,55-,56-,63-,64-,96?,97?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-G(isobutyryl)](pCyEt)[2'-O-methyl-A(benzoyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-OMe-C(Ac)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-OMe-C(Ac)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-guanosine with an isobutyryl (iBu) protecting group, coupled with a 2'-O-Me-cytidine featuring an acetyl (Ac) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01149
Molecular Formula: C60H75N11O17P2
Molecular Weight: 1284.27
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: RBAOMSBFWCYTRH-UWSVYRINSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C60H75N11O17P2/c1-36(2)54(73)67-58-66-53-48(55(74)68-58)63-35-70(53)57-52(80-11)50(45(85-57)33-81-60(40-17-13-12-14-18-40,41-19-23-43(77-8)24-20-41)42-21-25-44(78-9)26-22-42)88-90(76,83-32-16-29-62)84-34-46-49(87-89(82-31-15-28-61)71(37(3)4)38(5)6)51(79-10)56(86-46)69-30-27-47(64-39(7)72)65-59(69)75/h12-14,17-27,30,35-38,45-46,49-52,56-57H,15-16,31-34H2,1-11H3,(H,64,65,72,75)(H2,66,67,68,73,74)/t45-,46-,49-,50-,51-,52-,56-,57-,89?,90?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-G(isobutyryl)](pCyEt)[2'-O-methyl-C(acetyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-OMe-A(Bz)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-A(Bz)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-adenosine with a benzoyl (Bz) protecting group, coupled with a 2'-O-Me-adenosine also featuring a benzoyl (Bz) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01150
Molecular Formula: C69H75N13O15P2
Molecular Weight: 1388.38
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: DKVYWLXZDOXBOR-VVBNRIDZSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C69H75N13O15P2/c1-44(2)82(45(3)4)98(91-36-18-34-70)96-57-54(95-67(59(57)88-7)80-42-76-55-61(72-40-74-63(55)80)78-65(83)46-20-12-9-13-21-46)39-93-99(85,92-37-19-35-71)97-58-53(94-68(60(58)89-8)81-43-77-56-62(73-41-75-64(56)81)79-66(84)47-22-14-10-15-23-47)38-90-69(48-24-16-11-17-25-48,49-26-30-51(86-5)31-27-49)50-28-32-52(87-6)33-29-50/h9-17,20-33,40-45,53-54,57-60,67-68H,18-19,36-39H2,1-8H3,(H,72,74,78,83)(H,73,75,79,84)/t53-,54-,57-,58-,59-,60-,67-,68-,98?,99?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-A(benzoyl)](pCyEt)[2'-O-methyl-A(benzoyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-OMe-A(Bz)](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-A(Bz)](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-adenosine with a benzoyl (Bz) protecting group, coupled with a 2'-O-Me-uridine. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01151
Molecular Formula: C61H70N10O16P2
Molecular Weight: 1261.23
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: AKASCWHWFRSDPA-DNSVLMGFSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C61H70N10O16P2/c1-39(2)71(40(3)4)88(81-33-15-30-62)86-51-48(85-58(53(51)78-7)69-32-29-49(72)67-60(69)74)36-83-89(75,82-34-16-31-63)87-52-47(84-59(54(52)79-8)70-38-66-50-55(64-37-65-56(50)70)68-57(73)41-17-11-9-12-18-41)35-80-61(42-19-13-10-14-20-42,43-21-25-45(76-5)26-22-43)44-23-27-46(77-6)28-24-44/h9-14,17-29,32,37-40,47-48,51-54,58-59H,15-16,33-36H2,1-8H3,(H,67,72,74)(H,64,65,68,73)/t47-,48-,51-,52-,53-,54-,58-,59-,88?,89?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-A(benzoyl)](pCyEt)[2'-O-Me-U-3'-cyanoethyl-Phosphoramidite]; AmUm; [5'-O-DMTr-2'-OMe-dA(Bz)](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]

[5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-uridine, coupled with a 2'-O-Me-uridine. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01152
Molecular Formula: C53H65N7O17P2
Molecular Weight: 1134.08
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: SGCPCDCDFYMHHQ-SXOXBGJYSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C53H65N7O17P2/c1-34(2)60(35(3)4)78(71-30-12-26-54)76-45-42(75-49(47(45)68-7)58-28-24-43(61)56-51(58)63)33-73-79(65,72-31-13-27-55)77-46-41(74-50(48(46)69-8)59-29-25-44(62)57-52(59)64)32-70-53(36-14-10-9-11-15-36,37-16-20-39(66-5)21-17-37)38-18-22-40(67-6)23-19-38/h9-11,14-25,28-29,34-35,41-42,45-50H,12-13,30-33H2,1-8H3,(H,56,61,63)(H,57,62,64)/t41-,42-,45-,46-,47-,48-,49-,50-,78?,79?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-U](pCyEt)[2'-O-Me-U-3'-cyanoethyl-Phosphoramidite]; UmUm; [5'-O-DMTr-2'-OMe-U](pCyEt)[2'-OMe-U-3'-CE Phosphoramidite]

[5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-cytidine with an acetyl (Ac) protecting group, coupled with a 2'-O-Me-uridine. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01153
Molecular Formula: C55H68N8O17P2
Molecular Weight: 1175.14
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: DBULUINHIAJRPG-AQFWJGNWSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C55H68N8O17P2/c1-35(2)63(36(3)4)81(74-31-13-27-56)79-47-44(78-51(49(47)71-8)62-30-26-46(65)60-54(62)67)34-76-82(68,75-32-14-28-57)80-48-43(77-52(50(48)72-9)61-29-25-45(58-37(5)64)59-53(61)66)33-73-55(38-15-11-10-12-16-38,39-17-21-41(69-6)22-18-39)40-19-23-42(70-7)24-20-40/h10-12,15-26,29-30,35-36,43-44,47-52H,13-14,31-34H2,1-9H3,(H,60,65,67)(H,58,59,64,66)/t43-,44-,47-,48-,49-,50-,51-,52-,81?,82?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-C(acetyl)](pCyEt)[2'-O-Me-U-3'-cyanoethyl-Phosphoramidite]; CmUm; [5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-OMe-U-3'-CE Phosphoramidite]

[5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-guanosine with an isobutyryl (iBu) protecting group, coupled with a 2'-O-Me-guanosine also featuring an isobutyryl (iBu) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01154
Molecular Formula: C63H79N13O17P2
Molecular Weight: 1352.35
Purity: ≥95% by HPLC
Appearance: White to off-white powder
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Storage: Store at -20 °C
InChIKey: MSQJFSFYPIFAMO-XXECTENDSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C63H79N13O17P2/c1-36(2)55(77)70-61-68-53-47(57(79)72-61)66-34-74(53)59-51(84-11)49(92-94(87-30-16-28-64)76(38(5)6)39(7)8)46(91-59)33-89-95(81,88-31-17-29-65)93-50-45(90-60(52(50)85-12)75-35-67-48-54(75)69-62(73-58(48)80)71-56(78)37(3)4)32-86-63(40-18-14-13-15-19-40,41-20-24-43(82-9)25-21-41)42-22-26-44(83-10)27-23-42/h13-15,18-27,34-39,45-46,49-52,59-60H,16-17,30-33H2,1-12H3,(H2,68,70,72,77,79)(H2,69,71,73,78,80)/t45-,46-,49-,50-,51-,52-,59-,60-,94?,95?/m1/s1
Synonyms: [5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

[5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-uridine, coupled with a 2'-O-Me-guanosine featuring an isobutyryl (iBu) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01155
Molecular Formula: C58H72N10O17P2
Molecular Weight: 1243.21
Purity: ≥95% by HPLC
Appearance: White to off-white powder
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Storage: Store at -20 °C
InChIKey: PJSNGMFTSNHPEB-DEECTFEXSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C58H72N10O17P2/c1-35(2)52(70)64-56-63-51-46(53(71)65-56)61-34-67(51)55-49(76-9)47(84-86(79-30-14-27-59)68(36(3)4)37(5)6)44(83-55)33-81-87(73,80-31-15-28-60)85-48-43(82-54(50(48)77-10)66-29-26-45(69)62-57(66)72)32-78-58(38-16-12-11-13-17-38,39-18-22-41(74-7)23-19-39)40-20-24-42(75-8)25-21-40/h11-13,16-26,29,34-37,43-44,47-50,54-55H,14-15,30-33H2,1-10H3,(H,62,69,72)(H2,63,64,65,70,71)/t43-,44-,47-,48-,49-,50-,54-,55-,86?,87?/m1/s1
Synonyms: [5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

[5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-cytidine with an acetyl (Ac) protecting group, coupled with a 2'-O-Me-guanosine featuring an isobutyryl (iBu) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01156
Molecular Formula: C60H75N11O17P2
Molecular Weight: 1284.27
Purity: ≥95% by HPLC
Appearance: White to off-white powder
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Storage: Store at -20 °C
InChIKey: JREOEYAVHNOKMM-UWSVYRINSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C60H75N11O17P2/c1-36(2)54(73)67-58-66-53-48(55(74)68-58)63-35-70(53)57-51(79-10)49(87-89(82-31-15-28-61)71(37(3)4)38(5)6)46(86-57)34-84-90(76,83-32-16-29-62)88-50-45(85-56(52(50)80-11)69-30-27-47(64-39(7)72)65-59(69)75)33-81-60(40-17-13-12-14-18-40,41-19-23-43(77-8)24-20-41)42-21-25-44(78-9)26-22-42/h12-14,17-27,30,35-38,45-46,49-52,56-57H,15-16,31-34H2,1-11H3,(H,64,65,72,75)(H2,66,67,68,73,74)/t45-,46-,49-,50-,51-,52-,56-,57-,89?,90?/m1/s1
Synonyms: [5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

[5'-O-DMTr-2'-OMe-A(Bz)](P-thio-pCyEt) [2'-O-Me-A(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-A(Bz)](P-thio-pCyEt) [2'-O-Me-A(Bz)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-adenosine with a benzoyl (Bz) protecting group, coupled with a 2'-O-Me-adenosine also featuring a benzoyl (Bz) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01157
Molecular Formula: C69H75N13O14P2S
Molecular Weight: 1404.44
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: XCGJIPXEZUXVNV-YKUGJANUSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=NC=NC32)NC(=O)C=4C=CC=CC4)C1OC)COP(=S)(OCCC#N)OC5C(OC(N6C=NC=7C(=NC=NC76)NC(=O)C=8C=CC=CC8)C5OC)COC(C=9C=CC=CC9)(C%10=CC=C(OC)C=C%10)C%11=CC=C(OC)C=C%11)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphorothioyl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C69H75N13O14P2S/c1-44(2)82(45(3)4)97(90-36-18-34-70)95-57-54(94-67(59(57)87-7)80-42-76-55-61(72-40-74-63(55)80)78-65(83)46-20-12-9-13-21-46)39-92-98(99,91-37-19-35-71)96-58-53(93-68(60(58)88-8)81-43-77-56-62(73-41-75-64(56)81)79-66(84)47-22-14-10-15-23-47)38-89-69(48-24-16-11-17-25-48,49-26-30-51(85-5)31-27-49)50-28-32-52(86-6)33-29-50/h9-17,20-33,40-45,53-54,57-60,67-68H,18-19,36-39H2,1-8H3,(H,72,74,78,83)(H,73,75,79,84)/t53-,54-,57-,58-,59-,60-,67-,68-,97?,98?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-A(benzoyl)](P-thio-pCyEt) [2'-O-Me-A(benzoyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-OMe-A(Bz)](pCyEt) [2'-F-dA(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-A(Bz)](pCyEt) [2'-F-dA(Bz)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-adenosine with a benzoyl (Bz) protecting group, coupled with a 2'-fluoro-deoxyadenosine (2'-F-dA) also featuring a benzoyl (Bz) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01158
Molecular Formula: C68H72FN13O14P2
Molecular Weight: 1376.35
Purity: ≥95% by HPLC
Appearance: White to off-white powder
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InChIKey: XJSBJPLHTAATIR-YKZUEJCGSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C68H72FN13O14P2/c1-43(2)82(44(3)4)97(90-35-17-33-70)95-57-53(93-66(54(57)69)80-41-76-55-60(72-39-74-62(55)80)78-64(83)45-19-11-8-12-20-45)38-92-98(85,91-36-18-34-71)96-58-52(94-67(59(58)88-7)81-42-77-56-61(73-40-75-63(56)81)79-65(84)46-21-13-9-14-22-46)37-89-68(47-23-15-10-16-24-47,48-25-29-50(86-5)30-26-48)49-27-31-51(87-6)32-28-49/h8-16,19-32,39-44,52-54,57-59,66-67H,17-18,35-38H2,1-7H3,(H,72,74,78,83)(H,73,75,79,84)/t52-,53-,54-,57-,58-,59-,66-,67-,97?,98?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-A(benzoyl)](pCyEt)[2'-Fluoro-dA(benzoyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-F-dC(Ac)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-F-dC(Ac)-3'-CE-Phosphoramidite] is a specialized building block used in the chemical synthesis of modified oligonucleotides. The modifications to the guanine and cytidine bases, including methoxy, fluoro, and protective groups, improve the properties of nucleic acids for research and therapeutic applications. This compound is significant in biochemical research and therapeutic development, contributing to advancements in genetic and molecular medicine.
CAT: BRP-01159
Molecular Formula: C59H72FN11O16P2
Molecular Weight: 1272.21
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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InChIKey: JWJXHOVUDQYNQH-FVZAZZLTSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C59H72FN11O16P2/c1-35(2)53(73)67-57-66-52-48(54(74)68-57)63-34-70(52)56-51(79-10)50(44(85-56)32-80-59(39-16-12-11-13-17-39,40-18-22-42(77-8)23-19-40)41-20-24-43(78-9)25-21-41)87-89(76,82-31-15-28-62)83-33-45-49(86-88(81-30-14-27-61)71(36(3)4)37(5)6)47(60)55(84-45)69-29-26-46(64-38(7)72)65-58(69)75/h11-13,16-26,29,34-37,44-45,47,49-51,55-56H,14-15,30-33H2,1-10H3,(H,64,65,72,75)(H2,66,67,68,73,74)/t44-,45-,47-,49-,50-,51-,55-,56-,88?,89?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-G(isobutyryl)](pCyEt)[2'-Fluoro-dC(acetyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-F-dC(Ac)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-F-dC(Ac)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-fluoro-deoxycytidine (2'-F-dC) with an acetyl (Ac) protecting group, coupled with a 2'-O-Me-adenosine featuring a benzoyl (Bz) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01160
Molecular Formula: C62H70FN11O15P2
Molecular Weight: 1290.25
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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InChIKey: FLVRUPWUNDBISN-QKVILFJXSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(6-benzamido-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C62H70FN11O15P2/c1-39(2)74(40(3)4)90(83-33-15-30-64)88-54-49(87-60(55(54)81-8)73-38-68-52-56(66-37-67-57(52)73)71-58(76)42-17-11-9-12-18-42)36-85-91(78,84-34-16-31-65)89-53-48(86-59(51(53)63)72-32-29-50(69-41(5)75)70-61(72)77)35-82-62(43-19-13-10-14-20-43,44-21-25-46(79-6)26-22-44)45-23-27-47(80-7)28-24-45/h9-14,17-29,32,37-40,48-49,51,53-55,59-60H,15-16,33-36H2,1-8H3,(H,66,67,71,76)(H,69,70,75,77)/t48-,49-,51-,53-,54-,55-,59-,60-,90?,91?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-Fluoro-dC(acetyl)](pCyEt)[2'-O-methyl-A(benzoyl)-3'-cyanoethyl-Phosphoramidite]; CfAm; [5'-O-DMTr-2'-F-C(Ac)](pCyEt)[2'-OMe dA(Bz)-3'-CE-Phosphoramidite]; [5'-O-DMTr-2'-F-C(Ac)](pCyEt)[2'-OMe_x005f_x0002_A(Bz)-3'-CE Phosphoramidite]

[5'-O-DMTr-2'-F-dA(Bz)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-F-dA(Bz)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-fluoro-deoxyadenosine (2'-F-dA) with a benzoyl (Bz) protecting group, coupled with a 2'-O-Me-adenosine also featuring a benzoyl (Bz) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01161
Molecular Formula: C68H72FN13O14P2
Molecular Weight: 1376.35
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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InChIKey: IEMHYBRYTKNWOB-YKZUEJCGSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C68H72FN13O14P2/c1-43(2)82(44(3)4)97(90-35-17-33-70)95-58-53(94-67(59(58)88-7)81-42-77-56-61(73-40-75-63(56)81)79-65(84)46-21-13-9-14-22-46)38-92-98(85,91-36-18-34-71)96-57-52(93-66(54(57)69)80-41-76-55-60(72-39-74-62(55)80)78-64(83)45-19-11-8-12-20-45)37-89-68(47-23-15-10-16-24-47,48-25-29-50(86-5)30-26-48)49-27-31-51(87-6)32-28-49/h8-16,19-32,39-44,52-54,57-59,66-67H,17-18,35-38H2,1-7H3,(H,72,74,78,83)(H,73,75,79,84)/t52-,53-,54-,57-,58-,59-,66-,67-,97?,98?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-Fluoro-deoxyadenosine(benzoyl)](pCyEt)[2'-O-methyl-A(benzoyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-F-dG(iBu)](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-F-dG(iBu)](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-fluoro-deoxyguanosine (2'-F-dG) with an isobutyryl (iBu) protecting group, coupled with a 2'-O-Me-uridine. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01162
Molecular Formula: C57H69FN10O16P2
Molecular Weight: 1231.16
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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InChIKey: XPODDDMZDAYSLB-DDOFDVFASA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C57H69FN10O16P2/c1-34(2)51(70)64-55-63-50-46(52(71)65-55)61-33-67(50)53-45(58)47(42(81-53)31-77-57(37-15-11-10-12-16-37,38-17-21-40(74-7)22-18-38)39-19-23-41(75-8)24-20-39)84-86(73,79-30-14-27-60)80-32-43-48(83-85(78-29-13-26-59)68(35(3)4)36(5)6)49(76-9)54(82-43)66-28-25-44(69)62-56(66)72/h10-12,15-25,28,33-36,42-43,45,47-49,53-54H,13-14,29-32H2,1-9H3,(H,62,69,72)(H2,63,64,65,70,71)/t42-,43-,45-,47-,48-,49-,53-,54-,85?,86?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-Fluoro-deoxyguanosine(isobutyryl)](pCyEt)[2'-O-methyl-U-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-F-dG(iBu)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-F-dG(iBu)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-fluoro-deoxyguanosine (2'-F-dG) with an isobutyryl (iBu) protecting group, coupled with a 2'-O-Me-adenosine featuring a benzoyl (Bz) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01163
Molecular Formula: C65H74FN13O15P2
Molecular Weight: 1358.33
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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InChIKey: LRTYNAWUQYQBND-XLCQULBRSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C65H74FN13O15P2/c1-39(2)59(80)75-64-74-58-52(61(82)76-64)72-38-78(58)62-50(66)53(48(91-62)34-87-65(43-20-14-11-15-21-43,44-22-26-46(84-7)27-23-44)45-24-28-47(85-8)29-25-45)94-96(83,89-33-17-31-68)90-35-49-54(93-95(88-32-16-30-67)79(40(3)4)41(5)6)55(86-9)63(92-49)77-37-71-51-56(69-36-70-57(51)77)73-60(81)42-18-12-10-13-19-42/h10-15,18-29,36-41,48-50,53-55,62-63H,16-17,32-35H2,1-9H3,(H,69,70,73,81)(H2,74,75,76,80,82)/t48-,49-,50-,53-,54-,55-,62-,63-,95?,96?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-Fluoro-deoxyguanosine(isobutyryl)](pCyEt)[2'-O-methyl-A(benzoyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-F-dU](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-F-dU](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-fluoro-deoxyuridine (2'-F-dU), coupled with a 2'-O-Me-uridine. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01164
Molecular Formula: C52H62FN7O16P2
Molecular Weight: 1122.05
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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InChIKey: HHTCFGCOBNOOGE-OSAWNNERSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C52H62FN7O16P2/c1-33(2)60(34(3)4)77(70-29-11-25-54)75-46-41(74-49(47(46)68-7)59-28-24-43(62)57-51(59)64)32-72-78(65,71-30-12-26-55)76-45-40(73-48(44(45)53)58-27-23-42(61)56-50(58)63)31-69-52(35-13-9-8-10-14-35,36-15-19-38(66-5)20-16-36)37-17-21-39(67-6)22-18-37/h8-10,13-24,27-28,33-34,40-41,44-49H,11-12,29-32H2,1-7H3,(H,56,61,63)(H,57,62,64)/t40-,41-,44-,45-,46-,47-,48-,49-,77?,78?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-Fluoro-deoxyuridine](pCyEt)[2'-O-methyl-U-3'-cyanoethyl-Phosphoramidite]; UfUm; [5'-O-DMTr-2'-F-U](pCyEt)[2'-OMe-U-3'-CE Phosphoramidite]

[5'-O-DMTr-2'-F-dA(Bz)](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-F-dA(Bz)](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-fluoro-deoxyadenosine (2'-F-dA) with a benzoyl (Bz) protecting group, coupled with a 2'-O-Me-uridine. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01165
Molecular Formula: C60H67FN10O15P2
Molecular Weight: 1249.20
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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InChIKey: MLTDAQATQGSCMC-YJAGKEHNSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C60H67FN10O15P2/c1-38(2)71(39(3)4)87(80-32-14-29-62)85-52-47(84-58(53(52)78-7)69-31-28-48(72)67-59(69)74)35-82-88(75,81-33-15-30-63)86-51-46(83-57(49(51)61)70-37-66-50-54(64-36-65-55(50)70)68-56(73)40-16-10-8-11-17-40)34-79-60(41-18-12-9-13-19-41,42-20-24-44(76-5)25-21-42)43-22-26-45(77-6)27-23-43/h8-13,16-28,31,36-39,46-47,49,51-53,57-58H,14-15,32-35H2,1-7H3,(H,67,72,74)(H,64,65,68,73)/t46-,47-,49-,51-,52-,53-,57-,58-,87?,88?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-Fluoro-deoxyadenosine(benzoyl)](pCyEt)[2'-O-methyl-U-3'-cyanoethyl-Phosphoramidite]; AfUm; [5'-O-DMTr-2'-F A(Bz)](pCyEt)[2'-OMe-U-3'-CE Phosphoramidite]

[5'-O-DMTr-2'-F-dU](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-F-dU](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-fluoro-deoxyuridine (2'-F-dU), coupled with a 2'-O-Me-adenosine featuring a benzoyl (Bz) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01166
Molecular Formula: C60H67FN10O15P2
Molecular Weight: 1249.20
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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InChIKey: MXFDTLAJATVWHH-YJAGKEHNSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C60H67FN10O15P2/c1-38(2)71(39(3)4)87(80-32-14-29-62)85-52-47(84-58(53(52)78-7)70-37-66-50-54(64-36-65-55(50)70)68-56(73)40-16-10-8-11-17-40)35-82-88(75,81-33-15-30-63)86-51-46(83-57(49(51)61)69-31-28-48(72)67-59(69)74)34-79-60(41-18-12-9-13-19-41,42-20-24-44(76-5)25-21-42)43-22-26-45(77-6)27-23-43/h8-13,16-28,31,36-39,46-47,49,51-53,57-58H,14-15,32-35H2,1-7H3,(H,67,72,74)(H,64,65,68,73)/t46-,47-,49-,51-,52-,53-,57-,58-,87?,88?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-Fluoro-deoxyuridine](pCyEt)[2'-O-methyl-A(benzoyl)-3'-cyanoethyl-Phosphoramidite]; UfAm; [5'-O-DMTr-2'-F-U](pCyEt)[2'-OMe-A(Bz)-3'-CE Phosphoramidite]

[5'-O-DMTr-2'-F-dC(Ac)](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-F-dC(Ac)](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-fluoro-deoxycytidine (2'-F-dC) with an acetyl (Ac) protecting group, coupled with a 2'-O-Me-uridine. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.
CAT: BRP-01167
Molecular Formula: C54H65FN8O16P2
Molecular Weight: 1163.10
Purity: ≥97% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: VRMGJNPMTYRHKS-JFJKBCMNSA-N
IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C54H65FN8O16P2/c1-34(2)63(35(3)4)80(73-30-12-26-56)78-48-43(77-51(49(48)71-8)62-29-25-45(65)60-53(62)67)33-75-81(68,74-31-13-27-57)79-47-42(76-50(46(47)55)61-28-24-44(58-36(5)64)59-52(61)66)32-72-54(37-14-10-9-11-15-37,38-16-20-40(69-6)21-17-38)39-18-22-41(70-7)23-19-39/h9-11,14-25,28-29,34-35,42-43,46-51H,12-13,30-33H2,1-8H3,(H,60,65,67)(H,58,59,64,66)/t42-,43-,46-,47-,48-,49-,50-,51-,80?,81?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-Fluoro-dC(acetyl)](pCyEt)[2'-O-methyl-U-3'-cyanoethyl-Phosphoramidite]
* Only for research. Not suitable for any diagnostic or therapeutic use.

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