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Phosphoramidites

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2'-Modified Phosphoramidites
(529/529) 2'-Phosphoramidites
(27/27) 3'-Modified Phosphoramidites
(201/201) 5'-Modified Phosphoramidites
(30/30) Arabino Phosphoramidites
(23/23) Base Protected Phosphoramidites (418/418) Dye Phosphoramidites
(53/53) Label Phosphoramidites
(80/80) Linker Phosphoramidites
(85/85) Other Phosphoramidites
(97/97) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(25/25) Spacer Phosphoramidites
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2'-OTBS G(iBu) ThioPhosphamidite

Description: 2'-OTBS G(iBu) ThioPhosphamidite is a reagent used in oligonucleotide synthesis. It contains a tert-butyldimethylsilyl (TBS) protecting group at the 2' position of ribose, guanosine (G) potentially protected with an isobutyl (iBu) group, and incorporates a thio modification. ThioPhosphamidite suggests the presence of a phosphoramidite moiety with a thiol (-SH) group attached. This reagent enables the controlled synthesis of oligonucleotides with thio modifications, providing specific chemical or biological functionalities to the resulting sequences.
CAT: BRP-00950
Molecular Formula: C54H67N6O9PS2Si
Molecular Weight: 1067.36
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: HXMLZPZNEIUXMQ-UFCBNZGASA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: S-(2-(((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate
InChI: InChI=1S/C54H67N6O9PS2Si/c1-36(2)48(61)57-52-56-47-44(49(62)58-52)55-35-60(47)50-46(69-73(8,9)53(3,4)5)45(68-70(59-30-16-17-31-59)72-33-32-71-51(63)37-18-12-10-13-19-37)43(67-50)34-66-54(38-20-14-11-15-21-38,39-22-26-41(64-6)27-23-39)40-24-28-42(65-7)29-25-40/h10-15,18-29,35-36,43,45-46,50H,16-17,30-34H2,1-9H3,(H2,56,57,58,61,62)/t43-,45-,46-,50-,70?/m1/s1
Synonyms: 5'-DMT-2'-OTBS-G(iBu)-3'-PS-Phosphoramidite; DMT-2'-OTBS-G(iBu)-3'-PS

SNA C(Bz) amidite

Description: SNA C(Bz) amidite is a reagent used in solid-phase oligonucleotide synthesis, particularly in the synthesis of SNA (serinol nucleic acid) oligomers. It contains cytosine (C) with a benzoyl (Bz) protecting group attached to the amino group of the nucleobase, allowing for controlled coupling reactions during synthesis. SNA, or serinol nucleic acid, is a type of nucleic acid analog. This reagent facilitates the synthesis of SNA oligonucleotides, which have applications in various biotechnological and therapeutic areas due to their unique properties.
CAT: BRP-00951
CAS: 1280548-93-7
Molecular Formula: C46H53N6O8P
Molecular Weight: 848.94
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: XRUGORVLABOZAD-PPCUMKKXSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OCC(NC(=O)CN1C=CC(=NC1=O)NC(=O)C=2C=CC=CC2)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C
IUPAC Name: (S)-2-(2-(4-benzamido-2-oxopyrimidin-1(2H)-yl)acetamido)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C46H53N6O8P/c1-33(2)52(34(3)4)61(59-29-13-27-47)60-32-39(48-43(53)30-51-28-26-42(50-45(51)55)49-44(54)35-14-9-7-10-15-35)31-58-46(36-16-11-8-12-17-36,37-18-22-40(56-5)23-19-37)38-20-24-41(57-6)25-21-38/h7-12,14-26,28,33-34,39H,13,29-32H2,1-6H3,(H,48,53)(H,49,50,54,55)/t39-,61?/m0/s1
Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2S)-2-[[2-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]acetyl]amino]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester; (2S)-2-[[2-[4-(Benzoylamino)-2-oxo-1(2H)-pyrimidinyl]acetyl]amino]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; (S)-SNA-C(Bz) Phosphoramidite

SNA A(Bz) amidite

Description: SNA A(Bz) amidite is a reagent used in solid-phase oligonucleotide synthesis, particularly for synthesizing SNA (serinol nucleic acid) oligomers. It contains adenine (A) with a benzoyl (Bz) protecting group attached to the amino group of the nucleobase, enabling controlled coupling reactions during synthesis. This reagent facilitates the synthesis of SNA oligonucleotides, which are nucleic acid analogs with modified backbone structures. SNA oligomers have applications in various fields such as molecular biology, diagnostics, and therapeutics due to their unique properties and potential functionalities.
CAT: BRP-00952
CAS: 1280548-94-8
Molecular Formula: C47H53N8O7P
Molecular Weight: 872.96
Purity: >97%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: ALIIACZLWAKPSI-QGGVFJROSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OCC(NC(=O)CN1C=NC=2C(=NC=NC21)NC(=O)C=3C=CC=CC3)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: (S)-2-(2-(6-benzamido-9H-purin-9-yl)acetamido)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C47H53N8O7P/c1-33(2)55(34(3)4)63(61-27-13-26-48)62-30-39(52-42(56)28-54-32-51-43-44(49-31-50-45(43)54)53-46(57)35-14-9-7-10-15-35)29-60-47(36-16-11-8-12-17-36,37-18-22-40(58-5)23-19-37)38-20-24-41(59-6)25-21-38/h7-12,14-25,31-34,39H,13,27-30H2,1-6H3,(H,52,56)(H,49,50,53,57)/t39-,63?/m0/s1
Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2S)-2-[[2-[6-(benzoylamino)-9H-purin-9-yl]acetyl]amino]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester; (2S)-2-[[2-[6-(Benzoylamino)-9H-purin-9-yl]acetyl]amino]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; (S)-SNA-A(Bz) Phosphoramidite

SNA G(iBu) amidite

Description: SNA G(iBu) amidite is a reagent utilized in solid-phase oligonucleotide synthesis, particularly for the synthesis of SNA (serinol nucleic acid) oligomers. It contains guanosine (G) with an isobutyl (iBu) protecting group attached, enabling controlled coupling reactions during synthesis. This reagent is essential for the synthesis of SNA oligonucleotides, which are nucleic acid analogs with modified backbone structures. SNA oligomers have diverse applications in biotechnology, diagnostics, and therapeutics due to their unique properties and potential functionalities.
CAT: BRP-00953
CAS: 1280548-97-1
Molecular Formula: C44H55N8O8P
Molecular Weight: 854.95
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: GIZOJVPZHAXHBF-VJZXMLMYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OCC(NC(=O)CN1C=NC=2C(=O)N=C(NC(=O)C(C)C)NC21)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C
IUPAC Name: (S)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-2-(2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)acetamido)propyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C44H55N8O8P/c1-29(2)41(54)49-43-48-40-39(42(55)50-43)46-28-51(40)25-38(53)47-35(27-60-61(59-24-12-23-45)52(30(3)4)31(5)6)26-58-44(32-13-10-9-11-14-32,33-15-19-36(56-7)20-16-33)34-17-21-37(57-8)22-18-34/h9-11,13-22,28-31,35H,12,24-27H2,1-8H3,(H,47,53)(H2,48,49,50,54,55)/t35-,61?/m0/s1
Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2S)-3-[bis(4-methoxyphenyl)phenylmethoxy]-2-[[2-[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]acetyl]amino]propyl 2-cyanoethyl ester; (2S)-3-[Bis(4-methoxyphenyl)phenylmethoxy]-2-[[2-[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]acetyl]amino]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; (S)-SNA-G(iBu) Phosphoramidite

DMTr PEG4 amidite

Description: DMTr PEG4 amidite is a reagent used in solid-phase oligonucleotide synthesis, where DMTr stands for 4,4'-dimethoxytrityl protecting group, and PEG4 refers to a tetraethylene glycol (PEG) spacer with four ethylene glycol units. This reagent allows for the controlled synthesis of oligonucleotides with a PEG4 spacer attached. PEGylation can impart various properties to oligonucleotides, such as increased solubility, stability, and reduced nonspecific binding, making them useful in applications like drug delivery, diagnostics, and bioconjugation.
CAT: BRP-00954
CAS: 158041-83-9
Molecular Formula: C38H53N2O8P
Molecular Weight: 696.82
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: VLNPELUWVKFPRH-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCCOCCOCCOCCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC
IUPAC Name: 3-[2-[2-[2-[2-[bis(4-methoxyphenyl)-phenylmethoxy]ethoxy]ethoxy]ethoxy]ethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C38H53N2O8P/c1-31(2)40(32(3)4)49(47-22-10-21-39)48-30-28-45-26-24-43-23-25-44-27-29-46-38(33-11-8-7-9-12-33,34-13-17-36(41-5)18-14-34)35-15-19-37(42-6)20-16-35/h7-9,11-20,31-32H,10,22-30H2,1-6H3
Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, 13,13-bis(4-methoxyphenyl)-13-phenyl-3,6,9,12-tetraoxatridec-1-yl 2-cyanoethyl ester; 13,13-Bis(4-methoxyphenyl)-13-phenyl-3,6,9,12-tetraoxatridec-1-yl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 13,13-bis(4-methoxyphenyl)-13-phenyl-3,6,9,12-tetraoxatridec-1-yl 2-cyanoethyl ester; 1,1-bis(4-methoxyphenyl)-1-phenyl-2,5,8,11-tetraoxatridecan-13-yl (2-cyanoethyl) diisopropylphosphoramidite; DMT-tetraethyloxy-Glycol CED phosphoramidite

1-DMTr-(S)-2-C9-Glycol amidite

Description: 1-DMTr-(S)-2-C9-Glycol amidite is a reagent used in solid-phase oligonucleotide synthesis. This reagent allows for the introduction of a chiral C9 spacer with a glycol moiety into oligonucleotides during synthesis. Chiral spacers can be useful for various applications, such as enhancing binding affinity or specificity in certain contexts.
CAT: BRP-00955
Molecular Formula: C41H59N2O5P
Molecular Weight: 690.91
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: VDNAYUVRQSPTOJ-VFNQWJAUSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC(COC(C=1C=CC=CC1)(C2=CC=C(OC)C=C2)C3=CC=C(OC)C=C3)CCCCCCCCC)N(C(C)C)C(C)C
IUPAC Name: 3-[[(2S)-1-[bis(4-methoxyphenyl)-phenylmethoxy]undecan-2-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C41H59N2O5P/c1-8-9-10-11-12-13-17-21-40(48-49(47-31-18-30-42)43(33(2)3)34(4)5)32-46-41(35-19-15-14-16-20-35,36-22-26-38(44-6)27-23-36)37-24-28-39(45-7)29-25-37/h14-16,19-20,22-29,33-34,40H,8-13,17-18,21,31-32H2,1-7H3/t40-,49?/m0/s1
Synonyms: Phosphoramidous acid, bis(1-methylethyl)-, 1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]decyl 2-cyanoethyl ester, (1S)-; (S)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)undecan-2-yl (2-cyanoethyl) diisopropylphosphoramidite
Related CAS: 178939-65-6 (R-isomer)

1-DMTr-2-(S)-propanediyl amidite

Description: 1-DMTr-2-(S)-propanediyl amidite is a reagent used in solid-phase oligonucleotide synthesis. This reagent allows for the introduction of a chiral propanediyl spacer into oligonucleotides during synthesis. Chiral spacers can impart specific properties or functionalities to oligonucleotides, making them useful for various applications in biotechnology and therapeutics.
CAT: BRP-00956
CAS: 161029-25-0
Molecular Formula: C33H43N2O5P
Molecular Weight: 578.69
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: XCLJWHBPKOARSH-VNFCCXQASA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC(C)COC(C=1C=CC=CC1)(C2=CC=C(OC)C=C2)C3=CC=C(OC)C=C3)N(C(C)C)C(C)C
IUPAC Name: (S)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C33H43N2O5P/c1-25(2)35(26(3)4)41(39-23-11-22-34)40-27(5)24-38-33(28-12-9-8-10-13-28,29-14-18-31(36-6)19-15-29)30-16-20-32(37-7)21-17-30/h8-10,12-21,25-27H,11,23-24H2,1-7H3/t27-,41?/m0/s1
Synonyms: Phosphoramidous acid, bis(1-methylethyl)-, 2-[bis(4-methoxyphenyl)phenylmethoxy]-1-methylethyl 2-cyanoethyl ester, (1S)-

1-DMTr-3-(S)-butanediyl amidite

Description: 1-DMTr-3-(S)-butanediyl amidite is a reagent used in solid-phase oligonucleotide synthesis. This reagent allows for the introduction of a chiral butanediyl spacer into oligonucleotides during synthesis. Chiral spacers can introduce specific properties or functionalities to oligonucleotides, useful for various applications in biotechnology and therapeutics.
CAT: BRP-00957
CAS: 161106-24-7
Molecular Formula: C34H45N2O5P
Molecular Weight: 592.72
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: QTYXEIMXWNEEOP-DHZXTJRXSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC(C)CCOC(C=1C=CC=CC1)(C2=CC=C(OC)C=C2)C3=CC=C(OC)C=C3)N(C(C)C)C(C)C
IUPAC Name: 3-[[(2S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]butan-2-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C34H45N2O5P/c1-26(2)36(27(3)4)42(40-24-11-23-35)41-28(5)22-25-39-34(29-12-9-8-10-13-29,30-14-18-32(37-6)19-15-30)31-16-20-33(38-7)21-17-31/h8-10,12-21,26-28H,11,22,24-25H2,1-7H3/t28-,42?/m0/s1
Synonyms: Phosphoramidous acid, bis(1-methylethyl)-, (1S)-3-[bis(4-methoxyphenyl)phenylmethoxy]-1-methylpropyl 2-cyanoethyl ester; Phosphoramidous acid, bis(1-methylethyl)-, 3-[bis(4-methoxyphenyl)phenylmethoxy]-1-methylpropyl 2-cyanoethyl ester, (1S)-; (S)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)butan-2-yl (2-cyanoethyl) diisopropylphosphoramidite

Propargyl C4 amidite

Description: Propargyl C4 amidite is a reagent used in oligonucleotide synthesis. This reagent allows for the introduction of a propargyl modification of the nucleobase during oligonucleotide synthesis. Propargyl modifications are useful for various applications such as click chemistry reactions for further functionalization or conjugation.
CAT: BRP-00958
CAS: 1173382-08-5
Molecular Formula: C16H29N2O3P
Molecular Weight: 328.39
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: LQEYCRIHZDOGRQ-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OCCCCOCC#C)N(C(C)C)C(C)C
IUPAC Name: 2-cyanoethyl (4-(prop-2-yn-1-yloxy)butyl) diisopropylphosphoramidite
InChI: InChI=1S/C16H29N2O3P/c1-6-11-19-12-7-8-13-20-22(21-14-9-10-17)18(15(2)3)16(4)5/h1,15-16H,7-9,11-14H2,2-5H3
Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 4-(2-propyn-1-yloxy)butyl ester; 2-Cyanoethyl 4-(2-propyn-1-yloxy)butyl N,N-bis(1-methylethyl)phosphoramidite

2'-OTBS Pyridinone amidite

Description: 2'-OTBS Pyridinone amidite is a reagent used in oligonucleotide synthesis, featuring a tert-butyldimethylsilyl (TBS) protecting group at the 2' position of ribose and incorporating a pyridinone moiety. This amidite enables the controlled synthesis of oligonucleotides with pyridinone modifications, offering unique properties or functionalities for applications in biotechnology and therapeutics.
CAT: BRP-00959
CAS: 179915-57-2
Molecular Formula: C46H62N3O8PSi
Molecular Weight: 844.08
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: FMVRDFSSWDAZFJ-VDXGOTTOSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=CC=CC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
IUPAC Name: 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-(2-oxopyridin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C46H62N3O8PSi/c1-33(2)49(34(3)4)58(54-31-17-29-47)56-42-40(55-44(48-30-16-15-20-41(48)50)43(42)57-59(10,11)45(5,6)7)32-53-46(35-18-13-12-14-19-35,36-21-25-38(51-8)26-22-36)37-23-27-39(52-9)28-24-37/h12-16,18-28,30,33-34,40,42-44H,17,31-32H2,1-11H3/t40-,42-,43-,44-,58?/m1/s1
Synonyms: Pyridin-2-one-CE Phosphoramidite; 5'-Dimethoxytrityl-pyridin-2-one-riboside, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Pyridin-2-one riboside CEP; 2(1H)-Pyridinone, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-; 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-2(1H)-pyridinone; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2-oxopyridin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; Pyridine-2-One CED phosphoramidite

Tocopherol amidite

Description: Tocopherol amidite is a reagent utilized in oligonucleotide synthesis. It contains a tocopherol moiety, which is a form of vitamin E, attached to an amidite group suitable for solid-phase synthesis. This reagent allows for the conjugation of tocopherol to oligonucleotides during synthesis. Tocopherol modifications can provide various properties such as increased stability, cellular uptake, or antioxidant activity to the resulting oligonucleotides, making them potentially useful for applications in drug delivery or other biomedical fields.
CAT: BRP-00960
CAS: 142386-74-1
Molecular Formula: C38H67N2O3P
Molecular Weight: 630.94
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: USUSEQXJHLFSON-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC1=C(C(=C(C2=C1OC(CC2)(C)CCCC(C)CCCC(C)CCCC(C)C)C)OP(N(C(C)C)C(C)C)OCCC#N)C
IUPAC Name: 3-[[di(propan-2-yl)amino]-[[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydrochromen-6-yl]oxy]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C38H67N2O3P/c1-27(2)17-13-18-30(7)19-14-20-31(8)21-15-23-38(12)24-22-35-34(11)36(32(9)33(10)37(35)42-38)43-44(41-26-16-25-39)40(28(3)4)29(5)6/h27-31H,13-24,26H2,1-12H3
Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester; 2-Cyanoethyl 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester; 2-cyanoethyl (2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-yl) diisopropylphosphoramidite

C8 amidite

Description: C8 amidite is a linker used in oligonucleotide synthesis. This linker provides a connection between the oligonucleotide and other molecules or surfaces during synthesis or conjugation processes. The ''C8'' designation indicates that it consists of a linker with an 8-carbon chain length. This linker facilitates the attachment of oligonucleotides to various molecules or surfaces, enabling specific applications such as biomolecule conjugation, solid-phase synthesis, or surface immobilization in bioassays.
CAT: BRP-00961
CAS: 194015-05-9
Molecular Formula: C17H35N2O2P
Molecular Weight: 330.45
Purity: >98%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: SYIZTDJMSOSVGQ-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CCCCCCCCOP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: 3-[[di(propan-2-yl)amino]-octoxyphosphanyl]oxypropanenitrile
InChI: InChI=1S/C17H35N2O2P/c1-6-7-8-9-10-11-14-20-22(21-15-12-13-18)19(16(2)3)17(4)5/h16-17H,6-12,14-15H2,1-5H3
Synonyms: 2-Cyanoethyl octyl diisopropylphosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl octyl ester; O-β-Cyanoethyl-O-octyl-N,N-diisopropyl phosphoramidite

C11 amidite

Description: C11 amidite is a linker used in oligonucleotide synthesis, consisting of an 11-carbon chain length. This linker facilitates the connection between the oligonucleotide and other molecules or surfaces during synthesis or conjugation processes. It provides flexibility and space between the oligonucleotide and the attached moiety, enabling various applications such as biomolecule conjugation, solid-phase synthesis, or surface immobilization in bioassays.
CAT: BRP-00962
CAS: 125676-85-9
Molecular Formula: C20H41N2O2P
Molecular Weight: 372.53
Purity: >98%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: IJPKCIKPYVOSEV-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OCCCCCCCCCCC)N(C(C)C)C(C)C
IUPAC Name: 2-cyanoethyl undecyl diisopropylphosphoramidite
InChI: InChI=1S/C20H41N2O2P/c1-6-7-8-9-10-11-12-13-14-17-23-25(24-18-15-16-21)22(19(2)3)20(4)5/h19-20H,6-15,17-18H2,1-5H3
Synonyms: 2-Cyanoethyl undecyl diisopropylphosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl undecyl ester; 2-Cyanoethyl undecyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl undecyl ester

C14 amidite

Description: C14 amidite is a linker utilized in oligonucleotide synthesis, featuring a 14-carbon chain length. This linker serves to connect the oligonucleotide to other molecules or surfaces during synthesis or conjugation processes. The ''C14'' designation indicates the length of the carbon chain in the linker. It provides flexibility and space between the oligonucleotide and the attached moiety, facilitating specific applications such as biomolecule conjugation, solid-phase synthesis, or surface immobilization in various bioassays.
CAT: BRP-00963
CAS: 198987-41-6
Molecular Formula: C23H47N2O2P
Molecular Weight: 414.62
Purity: >98%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: BGMXNCIZEALUBC-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CCCCCCCCCCCCCCOP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: 3-[[di(propan-2-yl)amino]-tetradecoxyphosphanyl]oxypropanenitrile
InChI: InChI=1S/C23H47N2O2P/c1-6-7-8-9-10-11-12-13-14-15-16-17-20-26-28(27-21-18-19-24)25(22(2)3)23(4)5/h22-23H,6-18,20-21H2,1-5H3
Synonyms: 2-Cyanoethyl tetradecyl diisopropylphosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl tetradecyl ester; 2-Cyanoethyl tetradecyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl tetradecyl ester

11-Br-C11 amidite

Description: 11-Br-C11 amidite is a reagent used in oligonucleotide synthesis, featuring an 11-carbon chain length with a bromine (Br) atom. This linker allows for the attachment of oligonucleotides to other molecules or surfaces during synthesis or conjugation processes. The bromine atom provides a reactive site for further functionalization or coupling reactions. It provides flexibility and space between the oligonucleotide and the attached moiety, enabling specific applications such as biomolecule conjugation, solid-phase synthesis, or surface immobilization in various bioassays.
CAT: BRP-00964
CAS: 804567-08-6
Molecular Formula: C20H40BrN2O2P
Molecular Weight: 451.43
Purity: >98%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: MZMSOHBMQFZJNM-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OCCCCCCCCCCCBr)N(C(C)C)C(C)C
IUPAC Name: 11-bromoundecyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C20H40BrN2O2P/c1-19(2)23(20(3)4)26(25-18-14-16-22)24-17-13-11-9-7-5-6-8-10-12-15-21/h19-20H,5-15,17-18H2,1-4H3
Synonyms: Phosphoramidous acid, bis(1-methylethyl)-, 11-bromoundecyl 2-cyanoethyl ester

2'-O-NMA PseudoUridine amidite

Description: 2'-O-NMA PseudoUridine amidite is a reagent used in oligonucleotide synthesis, featuring a modification at the 2' position of ribose with N-methylaminomethylene (NMA) and incorporating a pseudo-uridine moiety. This reagent enables the synthesis of oligonucleotides containing pseudo-uridine modifications, which can confer specific properties or functionalities to the resulting oligonucleotides. PseudoUridine modifications are valuable for applications in biotechnology and therapeutics due to their potential to enhance stability, specificity, or other desired characteristics.
CAT: BRP-00965
Molecular Formula: C42H52N5O10P
Molecular Weight: 817.88
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: NHSKCVXWHUBLRO-AZUJSHLHSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-(2-(methylamino)-2-oxoethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C42H52N5O10P/c1-27(2)47(28(3)4)58(55-23-11-22-43)57-38-35(56-37(39(38)53-26-36(48)44-5)34-24-45-41(50)46-40(34)49)25-54-42(29-12-9-8-10-13-29,30-14-18-32(51-6)19-15-30)31-16-20-33(52-7)21-17-31/h8-10,12-21,24,27-28,35,37-39H,11,23,25-26H2,1-7H3,(H,44,48)(H2,45,46,49,50)/t35-,37+,38-,39+,58?/m1/s1

2'-O-NMA N1-Methyl PseudoUridine amidite

Description: 2'-O-NMA N1-Methyl PseudoUridine amidite is a reagent employed in oligonucleotide synthesis. It involves a modification at the 2' position of ribose with N-methylaminomethylene (NMA) and incorporates N1-Methyl PseudoUridine, a modified nucleoside resembling uridine with a methyl group attached to the nitrogen at position 1. This reagent enables the synthesis of oligonucleotides with N1-Methyl PseudoUridine modifications, offering specific properties or functionalities to the resulting oligonucleotides. These modifications can be advantageous for various biotechnological and therapeutic applications, providing enhanced stability or other desired characteristics.
CAT: BRP-00966
Molecular Formula: C43H54N5O10P
Molecular Weight: 831.90
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: PRKXXSDXURDTSF-ZIVCPKBRSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-(2-(methylamino)-2-oxoethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C43H54N5O10P/c1-28(2)48(29(3)4)59(56-24-12-23-44)58-39-36(57-38(40(39)54-27-37(49)45-5)35-25-47(6)42(51)46-41(35)50)26-55-43(30-13-10-9-11-14-30,31-15-19-33(52-7)20-16-31)32-17-21-34(53-8)22-18-32/h9-11,13-22,25,28-29,36,38-40H,12,24,26-27H2,1-8H3,(H,45,49)(H,46,50,51)/t36-,38+,39-,40+,59?/m1/s1

2'-OEt-S-S-tBu C(Bz) amidite

Description: 2'-OEt-S-S-tBu C(Bz) amidite is a reagent used in oligonucleotide synthesis, containing a disulfide linkage with tert-butyl (tBu) termination and cytosine protected with benzoyl (Bz) group at the 2' position of ribose. This modification allows for the introduction of reversible crosslinking or enhanced stability properties to the resulting oligonucleotides.
CAT: BRP-00967
CAS: 176747-35-6
Molecular Formula: C52H64N5O9PS2
Molecular Weight: 998.22
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: GGJPSSSMERVJTA-YOVDOAOFSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=CC(=NC2=O)NC(=O)C=3C=CC=CC3)C1OCCSSC(C)(C)C)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(tert-butyldisulfaneyl)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C52H64N5O9PS2/c1-36(2)57(37(3)4)67(64-32-16-30-53)66-46-44(35-63-52(39-19-14-11-15-20-39,40-21-25-42(60-8)26-22-40)41-23-27-43(61-9)28-24-41)65-49(47(46)62-33-34-68-69-51(5,6)7)56-31-29-45(55-50(56)59)54-48(58)38-17-12-10-13-18-38/h10-15,17-29,31,36-37,44,46-47,49H,16,32-35H2,1-9H3,(H,54,55,58,59)/t44-,46-,47-,49-,67?/m1/s1
Synonyms: Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[2-[(1,1-dimethylethyl)dithio]ethyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

Thio(Bz) C6 amidite

Description: Thio(Bz) C6 amidite is a reagent used in oligonucleotide synthesis, featuring a thiol modification with a benzoyl (Bz) protecting group and a 6-carbon linker. This reagent allows for the introduction of a thiol-modified linker with a 6-carbon chain length into oligonucleotide sequences during synthesis. Thiol modifications can be employed for various applications such as covalent conjugation, labeling, or surface immobilization in bioassays.
CAT: BRP-00968
CAS: 176640-52-1
Molecular Formula: C22H35N2O3PS
Molecular Weight: 438.57
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: UDUVXNZCIKTQTP-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OCCCCCCSC(=O)C=1C=CC=CC1)N(C(C)C)C(C)C
IUPAC Name: S-(6-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)hexyl) benzothioate
InChI: InChI=1S/C22H35N2O3PS/c1-19(2)24(20(3)4)28(27-17-12-15-23)26-16-10-5-6-11-18-29-22(25)21-13-8-7-9-14-21/h7-9,13-14,19-20H,5-6,10-12,16-18H2,1-4H3
Synonyms: Benzenecarbothioic acid, S-[6-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]hexyl] ester; S-[6-[[[Bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]hexyl] benzenecarbothioate

Thio(Ac) C6 amidite

Description: Thio(Ac) C6 amidite is a reagent used in oligonucleotide synthesis, featuring a thiol modification with an acetyl (Ac) protecting group and a 6-carbon linker. This reagent enables the introduction of a thiol-modified linker with a 6-carbon chain length into oligonucleotide sequences during synthesis. Thiol modifications can be utilized for various applications such as covalent conjugation, labeling, or surface immobilization in bioassays.
CAT: BRP-00969
CAS: 176640-51-0
Molecular Formula: C17H33N2O3PS
Molecular Weight: 376.50
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: YYZTVJUOQPJPLL-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OCCCCCCSC(=O)C)N(C(C)C)C(C)C
IUPAC Name: S-(6-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)hexyl) ethanethioate
InChI: InChI=1S/C17H33N2O3PS/c1-15(2)19(16(3)4)23(22-13-10-11-18)21-12-8-6-7-9-14-24-17(5)20/h15-16H,6-10,12-14H2,1-5H3
Synonyms: Ethanethioic acid, S-[6-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]hexyl] ester; S-[6-[[[Bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]hexyl] ethanethioate
* Only for research. Not suitable for any diagnostic or therapeutic use.

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