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What are Linker Phosphoramidites and Their Applications?

BOC RNA provides linker phosphoramidites used for DNA/RNA synthesis. Use an amino linker to conjugate biotin, fluorescein, or other modifiers and a reporter group to the 5'end of the oligonucleotide or adheres to the surface.

Advantages of linker phosphoramidites

Types and applications

As the DNA-based microarrays and multi-label diagnostic systems become increasingly important, the demand for easy preparation of functionalized oligonucleotides is also growing. At present, the most common modification is the primary amine at the 5'end of the oligonucleotide. TFA-protected and MMT-protected 5'-amino modifiers can be used in automatic synthesizers or manual coupling to connect various moieties to 5'-primary amines, including fluorescent dyes, biotin, and EDTA.

Main features of amino linkers

Quality control

Custom services

Custom manufacturing services are available to help develop or expand phosphoramidite compounds.

If you have any questions or requirements, please feel free to contact us.

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* Only for research. Not suitable for any diagnostic or therapeutic use.
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