Phosphoramidites - RNA / BOC Sciences

[5'-O-DMTr-2'-OMe-C(Ac)](P-thio-pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-C(Ac)](P-thio-pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. The modifications, including 2'-O-methyl, phosphorothioate, and protective groups like DMTr, acetyl, and isobutyryl, enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic development.

CAT: BRP-01137

MF: C60H75N11O16P2S

MF: 1300.33

Purity: ≥95% by HPLC

Appearance: White, off-white to light yellow powder

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InChIKey: WVXVWJZTQGZYKP-AITXLTLESA-N

IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphorothioyl)oxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C60H75N11O16P2S/c1-36(2)54(73)67-58-66-53-48(55(74)68-58)63-35-70(53)57-51(78-10)49(86-88(81-31-15-28-61)71(37(3)4)38(5)6)46(85-57)34-83-89(90,82-32-16-29-62)87-50-45(84-56(52(50)79-11)69-30-27-47(64-39(7)72)65-59(69)75)33-80-60(40-17-13-12-14-18-40,41-19-23-43(76-8)24-20-41)42-21-25-44(77-9)26-22-42/h12-14,17-27,30,35-38,45-46,49-52,56-57H,15-16,31-34H2,1-11H3,(H,64,65,72,75)(H2,66,67,68,73,74)/t45-,46-,49-,50-,51-,52-,56-,57-,88?,89?/m1/s1

Synonyms: [5'-O-DMTr-2'-O-Me-C(Ac)](P-thio-pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite

[5'-O-DMTr-2'-OMe-C(Ac)](P-thio-pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-C(Ac)](P-thio-pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite] is a chemically modified nucleoside phosphoramidite used in the synthesis of oligonucleotides. The modifications, including 2'-O-methyl, phosphorothioate, and various protecting groups like DMTr and acetyl, enhance the stability, binding affinity, and resistance to degradation of the resulting oligonucleotides. This makes it a valuable tool for biochemical research and therapeutic development.

CAT: BRP-01138

MF: C55H68N8O16P2S

MF: 1191.20

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: SPDNYGNFSNICHW-SZYQAGCUSA-N

IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphorothioyl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C55H68N8O16P2S/c1-35(2)63(36(3)4)80(73-31-13-27-56)78-47-44(77-51(49(47)70-8)62-30-26-46(65)60-54(62)67)34-75-81(82,74-32-14-28-57)79-48-43(76-52(50(48)71-9)61-29-25-45(58-37(5)64)59-53(61)66)33-72-55(38-15-11-10-12-16-38,39-17-21-41(68-6)22-18-39)40-19-23-42(69-7)24-20-40/h10-12,15-26,29-30,35-36,43-44,47-52H,13-14,31-34H2,1-9H3,(H,60,65,67)(H,58,59,64,66)/t43-,44-,47-,48-,49-,50-,51-,52-,80?,81?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-C(acetyl)](P-thio-pCyEt)[2'-O-methyl-U-3'-cyanoethyl-Phosphoramidite]

DMO-4AA-N,N-dimethyl phosphoramidochloridate

Description: DMO-4AA-N,N-dimethyl phosphoramidochloridate is a reagent used in oligonucleotide synthesis. It features a 4-amino group on the nucleobase and a dimethyl phosphoramidochloridate group, facilitating the introduction of specific phosphoramidite functionalities. This enhances the chemical stability and hybridization properties of the synthesized oligonucleotides, making it valuable for research and therapeutic applications.

CAT: BRP-01139

MF: C57H59ClN14O8P2

MF: 1165.59

Purity: ≥95% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: DFGOMKBKDOPFFZ-OJYZEZLKSA-N

IUPAC Name: ((2S,6R)-6-(6-benzamido-9H-purin-9-yl)-4-((((2S,6R)-6-(6-benzamido-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methoxy)(dimethylamino)phosphoryl)morpholin-2-yl)methyl dimethylphosphoramidochloridate

InChI: InChI=1S/C57H59ClN14O8P2/c1-67(2)81(58,75)77-34-46-31-70(33-48(80-46)72-39-64-50-52(60-37-62-54(50)72)66-56(74)41-22-12-6-13-23-41)82(76,68(3)4)78-35-45-30-69(57(42-24-14-7-15-25-42,43-26-16-8-17-27-43)44-28-18-9-19-29-44)32-47(79-45)71-38-63-49-51(59-36-61-53(49)71)65-55(73)40-20-10-5-11-21-40/h5-29,36-39,45-48H,30-35H2,1-4H3,(H,59,61,65,73)(H,60,62,66,74)/t45-,46-,47+,48+,81?,82?/m0/s1

Synonyms: DMO-4A(Bz)A(Bz)-N,N-dimethyl phosphoramidochloridate

DMO-4CA-N,N-dimethyl phosphoramidochloridate

Description: DMO-4CA-N,N-dimethyl phosphoramidochloridate is a reagent employed in oligonucleotide synthesis. It contains a 4-amino group on the cytosine nucleobase and a dimethyl phosphoramidochloridate group, allowing for the introduction of specific phosphoramidite functionalities. This enhances the stability and binding properties of the resulting oligonucleotides, making it useful for various research and therapeutic applications.

CAT: BRP-01140

MF: C56H59ClN12O9P2

MF: 1141.56

Purity: ≥95% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: VVSWCOAQQJYWEF-INJDICEFSA-N

IUPAC Name: ((2S,6R)-6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-((((2S,6R)-6-(6-benzamido-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methoxy)(dimethylamino)phosphoryl)morpholin-2-yl)methyl dimethylphosphoramidochloridate

InChI: InChI=1S/C56H59ClN12O9P2/c1-64(2)79(57,73)75-36-46-33-67(35-49(78-46)68-31-30-47(62-55(68)72)61-53(70)40-20-10-5-11-21-40)80(74,65(3)4)76-37-45-32-66(56(42-24-14-7-15-25-42,43-26-16-8-17-27-43)44-28-18-9-19-29-44)34-48(77-45)69-39-60-50-51(58-38-59-52(50)69)63-54(71)41-22-12-6-13-23-41/h5-31,38-39,45-46,48-49H,32-37H2,1-4H3,(H,58,59,63,71)(H,61,62,70,72)/t45-,46-,48+,49+,79?,80?/m0/s1

Synonyms: DMO-4C(Bz)A(Bz)-N,N-dimethyl phosphoramidochloridate

DMO-4CC-N,N-dimethyl phosphoramidochloridate

Description: DMO-4CC-N,N-dimethyl phosphoramidochloridate is a reagent used in oligonucleotide synthesis, featuring a 4-amino group on the cytosine nucleobase and a dimethyl phosphoramidochloridate group. It enables the introduction of specific phosphoramidite functionalities, enhancing the stability and binding affinity of the synthesized oligonucleotides. This reagent is valuable for research and therapeutic applications in nucleic acid chemistry.

CAT: BRP-01141

MF: C55H59ClN10O10P2

MF: 1117.52

Purity: ≥95% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: AJXQYLRIFMQLHF-XWKZHAFPSA-N

IUPAC Name: ((2S,6R)-6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-((((2S,6R)-6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methoxy)(dimethylamino)phosphoryl)morpholin-2-yl)methyl dimethylphosphoramidochloridate

InChI: InChI=1S/C55H59ClN10O10P2/c1-61(2)77(56,71)73-38-46-35-64(37-50(76-46)66-33-31-48(60-54(66)70)58-52(68)41-22-12-6-13-23-41)78(72,62(3)4)74-39-45-34-63(36-49(75-45)65-32-30-47(59-53(65)69)57-51(67)40-20-10-5-11-21-40)55(42-24-14-7-15-25-42,43-26-16-8-17-27-43)44-28-18-9-19-29-44/h5-33,45-46,49-50H,34-39H2,1-4H3,(H,57,59,67,69)(H,58,60,68,70)/t45-,46-,49+,50+,77?,78?/m0/s1

Synonyms: DMO-4C(Bz)C(Bz)-N,N-dimethyl phosphoramidochloridate

DMO-4AC-N,N-dimethyl phosphoramidochloridate

Description: DMO-4AC-N,N-dimethyl phosphoramidochloridate is a reagent used in oligonucleotide synthesis. It contains a 4-amino group on the adenine nucleobase and a dimethyl phosphoramidochloridate group, allowing for the introduction of specific phosphoramidite functionalities. This enhances the stability, binding affinity, and overall performance of the resulting oligonucleotides, making it valuable for research and therapeutic applications.

CAT: BRP-01142

MF: C56H59ClN12O9P2

MF: 1141.56

Purity: ≥95% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: MGRBUUDLZWZYSJ-INJDICEFSA-N

IUPAC Name: ((2S,6R)-4-((((2S,6R)-6-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-tritylmorpholin-2-yl)methoxy)(dimethylamino)phosphoryl)-6-(6-benzamido-9H-purin-9-yl)morpholin-2-yl)methyl dimethylphosphoramidochloridate

InChI: InChI=1S/C56H59ClN12O9P2/c1-64(2)79(57,73)75-36-46-33-67(35-49(78-46)69-39-60-50-51(58-38-59-52(50)69)63-54(71)41-22-12-6-13-23-41)80(74,65(3)4)76-37-45-32-66(34-48(77-45)68-31-30-47(62-55(68)72)61-53(70)40-20-10-5-11-21-40)56(42-24-14-7-15-25-42,43-26-16-8-17-27-43)44-28-18-9-19-29-44/h5-31,38-39,45-46,48-49H,32-37H2,1-4H3,(H,58,59,63,71)(H,61,62,70,72)/t45-,46-,48+,49+,79?,80?/m0/s1

Synonyms: DMO-4A(Bz)C(Bz)-N,N-dimethyl phosphoramidochloridate

[5'-O-DMTr-2'-OMe-A(Bz)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-A(Bz)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It contains a 5'-O-DMTr-2'-OMe-adenosine with a benzoyl (Bz) protecting group, coupled with a 2'-O-Me-guanosine featuring an isobutyryl (iBu) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01143

MF: C66H77N13O16P2

MF: 1370.36

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: VVYUEZXTVXFAIS-LLYQIHFBSA-N

IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C66H77N13O16P2/c1-40(2)60(80)75-65-74-59-52(62(82)76-65)72-39-78(59)63-55(86-9)53(94-96(89-33-17-31-67)79(41(3)4)42(5)6)50(93-63)36-91-97(83,90-34-18-32-68)95-54-49(92-64(56(54)87-10)77-38-71-51-57(69-37-70-58(51)77)73-61(81)43-19-13-11-14-20-43)35-88-66(44-21-15-12-16-22-44,45-23-27-47(84-7)28-24-45)46-25-29-48(85-8)30-26-46/h11-16,19-30,37-42,49-50,53-56,63-64H,17-18,33-36H2,1-10H3,(H,69,70,73,81)(H2,74,75,76,80,82)/t49-,50-,53-,54-,55-,56-,63-,64-,96?,97?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-A(benzoyl)](pCyEt)[2'-O-Me-G(isobutyryl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It features a 5'-O-DMTr-2'-OMe-guanosine with an isobutyryl (iBu) protecting group, coupled with a 2'-O-Me-uridine. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01144

MF: C58H72N10O17P2

MF: 1243.21

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: KJCRHKCTDIUGLT-DEECTFEXSA-N

IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C58H72N10O17P2/c1-35(2)52(70)64-56-63-51-46(53(71)65-56)61-34-67(51)55-50(77-10)48(43(82-55)32-78-58(38-16-12-11-13-17-38,39-18-22-41(74-7)23-19-39)40-20-24-42(75-8)25-21-40)85-87(73,80-31-15-28-60)81-33-44-47(84-86(79-30-14-27-59)68(36(3)4)37(5)6)49(76-9)54(83-44)66-29-26-45(69)62-57(66)72/h11-13,16-26,29,34-37,43-44,47-50,54-55H,14-15,30-33H2,1-10H3,(H,62,69,72)(H2,63,64,65,70,71)/t43-,44-,47-,48-,49-,50-,54-,55-,86?,87?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-G(isobutyryl)](pCyEt)[2'-O-Me-U-3'-cyanoethyl-Phosphoramidite]; GmUm; [5'-O-DMTr-2'-OMe-G(ibu)](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]

[5'-O-DMTr-2'-OMe-A(Bz)](pCyEt)[2'-O-Me-C(Ac)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-A(Bz)](pCyEt)[2'-O-Me-C(Ac)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-adenosine with a benzoyl (Bz) protecting group, coupled with a 2'-O-Me-cytidine featuring an acetyl (Ac) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01145

MF: C63H73N11O16P2

MF: 1302.29

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: BRZMOTWQGIPHRX-ZXQRUMROSA-N

IUPAC Name: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C63H73N11O16P2/c1-40(2)74(41(3)4)91(84-34-16-31-64)89-53-50(88-60(55(53)81-8)72-33-30-51(69-42(5)75)70-62(72)77)37-86-92(78,85-35-17-32-65)90-54-49(87-61(56(54)82-9)73-39-68-52-57(66-38-67-58(52)73)71-59(76)43-18-12-10-13-19-43)36-83-63(44-20-14-11-15-21-44,45-22-26-47(79-6)27-23-45)46-24-28-48(80-7)29-25-46/h10-15,18-30,33,38-41,49-50,53-56,60-61H,16-17,34-37H2,1-9H3,(H,66,67,71,76)(H,69,70,75,77)/t49-,50-,53-,54-,55-,56-,60-,61-,91?,92?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-A(benzoyl)](pCyEt)[2'-O-Me-C(acetyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-cytidine with an acetyl (Ac) protecting group, coupled with a 2'-O-Me-adenosine featuring a benzoyl (Bz) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01146

MF: C63H73N11O16P2

MF: 1302.29

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: SPTHDVXNFLLFJO-ZXQRUMROSA-N

IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(6-benzamido-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C63H73N11O16P2/c1-40(2)74(41(3)4)91(84-34-16-31-64)89-53-50(88-61(55(53)81-8)73-39-68-52-57(66-38-67-58(52)73)71-59(76)43-18-12-10-13-19-43)37-86-92(78,85-35-17-32-65)90-54-49(87-60(56(54)82-9)72-33-30-51(69-42(5)75)70-62(72)77)36-83-63(44-20-14-11-15-21-44,45-22-26-47(79-6)27-23-45)46-24-28-48(80-7)29-25-46/h10-15,18-30,33,38-41,49-50,53-56,60-61H,16-17,34-37H2,1-9H3,(H,66,67,71,76)(H,69,70,75,77)/t49-,50-,53-,54-,55-,56-,60-,61-,91?,92?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-C(acetyl)](pCyEt)[2'-O-methyl-A(benzoyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-OMe-U](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-U](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It contains a 5'-O-DMTr-2'-OMe-uridine, coupled with a 2'-O-Me-adenosine featuring a benzoyl (Bz) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01147

MF: C61H70N10O16P2

MF: 1261.23

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: ASHCZTKKWZMQOE-DNSVLMGFSA-N

IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C61H70N10O16P2/c1-39(2)71(40(3)4)88(81-33-15-30-62)86-51-48(85-59(53(51)78-7)70-38-66-50-55(64-37-65-56(50)70)68-57(73)41-17-11-9-12-18-41)36-83-89(75,82-34-16-31-63)87-52-47(84-58(54(52)79-8)69-32-29-49(72)67-60(69)74)35-80-61(42-19-13-10-14-20-42,43-21-25-45(76-5)26-22-43)44-23-27-46(77-6)28-24-44/h9-14,17-29,32,37-40,47-48,51-54,58-59H,15-16,33-36H2,1-8H3,(H,67,72,74)(H,64,65,68,73)/t47-,48-,51-,52-,53-,54-,58-,59-,88?,89?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-U](pCyEt)[5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-A(benzoyl)-3'-cyanoethyl-Phosphoramidite]; [5'-O-DMTr-2'-OMe-U](pCyEt)[5'-O-DMTr-2'-OMe-A(Bz)-3'-CE-Phosphoramidite]

[5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-guanosine with an isobutyryl (iBu) protecting group, coupled with a 2'-O-Me-adenosine featuring a benzoyl (Bz) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01148

MF: C66H77N13O16P2

MF: 1370.36

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: VTDGJORSPBHICB-LLYQIHFBSA-N

IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C66H77N13O16P2/c1-40(2)60(80)75-65-74-59-52(62(82)76-65)72-39-78(59)64-56(87-10)54(49(92-64)35-88-66(44-21-15-12-16-22-44,45-23-27-47(84-7)28-24-45)46-25-29-48(85-8)30-26-46)95-97(83,90-34-18-32-68)91-36-50-53(94-96(89-33-17-31-67)79(41(3)4)42(5)6)55(86-9)63(93-50)77-38-71-51-57(69-37-70-58(51)77)73-61(81)43-19-13-11-14-20-43/h11-16,19-30,37-42,49-50,53-56,63-64H,17-18,33-36H2,1-10H3,(H,69,70,73,81)(H2,74,75,76,80,82)/t49-,50-,53-,54-,55-,56-,63-,64-,96?,97?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-G(isobutyryl)](pCyEt)[2'-O-methyl-A(benzoyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-OMe-C(Ac)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-OMe-C(Ac)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-guanosine with an isobutyryl (iBu) protecting group, coupled with a 2'-O-Me-cytidine featuring an acetyl (Ac) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01149

MF: C60H75N11O17P2

MF: 1284.27

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: RBAOMSBFWCYTRH-UWSVYRINSA-N

IUPAC Name: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C60H75N11O17P2/c1-36(2)54(73)67-58-66-53-48(55(74)68-58)63-35-70(53)57-52(80-11)50(45(85-57)33-81-60(40-17-13-12-14-18-40,41-19-23-43(77-8)24-20-41)42-21-25-44(78-9)26-22-42)88-90(76,83-32-16-29-62)84-34-46-49(87-89(82-31-15-28-61)71(37(3)4)38(5)6)51(79-10)56(86-46)69-30-27-47(64-39(7)72)65-59(69)75/h12-14,17-27,30,35-38,45-46,49-52,56-57H,15-16,31-34H2,1-11H3,(H,64,65,72,75)(H2,66,67,68,73,74)/t45-,46-,49-,50-,51-,52-,56-,57-,89?,90?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-G(isobutyryl)](pCyEt)[2'-O-methyl-C(acetyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-OMe-A(Bz)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-A(Bz)](pCyEt)[2'-OMe-A(Bz)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-adenosine with a benzoyl (Bz) protecting group, coupled with a 2'-O-Me-adenosine also featuring a benzoyl (Bz) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01150

MF: C69H75N13O15P2

MF: 1388.38

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: DKVYWLXZDOXBOR-VVBNRIDZSA-N

IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C69H75N13O15P2/c1-44(2)82(45(3)4)98(91-36-18-34-70)96-57-54(95-67(59(57)88-7)80-42-76-55-61(72-40-74-63(55)80)78-65(83)46-20-12-9-13-21-46)39-93-99(85,92-37-19-35-71)97-58-53(94-68(60(58)89-8)81-43-77-56-62(73-41-75-64(56)81)79-66(84)47-22-14-10-15-23-47)38-90-69(48-24-16-11-17-25-48,49-26-30-51(86-5)31-27-49)50-28-32-52(87-6)33-29-50/h9-17,20-33,40-45,53-54,57-60,67-68H,18-19,36-39H2,1-8H3,(H,72,74,78,83)(H,73,75,79,84)/t53-,54-,57-,58-,59-,60-,67-,68-,98?,99?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-A(benzoyl)](pCyEt)[2'-O-methyl-A(benzoyl)-3'-cyanoethyl-Phosphoramidite]

[5'-O-DMTr-2'-OMe-A(Bz)](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-A(Bz)](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-adenosine with a benzoyl (Bz) protecting group, coupled with a 2'-O-Me-uridine. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01151

MF: C61H70N10O16P2

MF: 1261.23

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: AKASCWHWFRSDPA-DNSVLMGFSA-N

IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C61H70N10O16P2/c1-39(2)71(40(3)4)88(81-33-15-30-62)86-51-48(85-58(53(51)78-7)69-32-29-49(72)67-60(69)74)36-83-89(75,82-34-16-31-63)87-52-47(84-59(54(52)79-8)70-38-66-50-55(64-37-65-56(50)70)68-57(73)41-17-11-9-12-18-41)35-80-61(42-19-13-10-14-20-42,43-21-25-45(76-5)26-22-43)44-23-27-46(77-6)28-24-44/h9-14,17-29,32,37-40,47-48,51-54,58-59H,15-16,33-36H2,1-8H3,(H,67,72,74)(H,64,65,68,73)/t47-,48-,51-,52-,53-,54-,58-,59-,88?,89?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-A(benzoyl)](pCyEt)[2'-O-Me-U-3'-cyanoethyl-Phosphoramidite]; AmUm; [5'-O-DMTr-2'-OMe-dA(Bz)](pCyEt)[2'-OMe-U-3'-CE-Phosphoramidite]

[5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-uridine, coupled with a 2'-O-Me-uridine. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01152

MF: C53H65N7O17P2

MF: 1134.08

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: SGCPCDCDFYMHHQ-SXOXBGJYSA-N

IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C53H65N7O17P2/c1-34(2)60(35(3)4)78(71-30-12-26-54)76-45-42(75-49(47(45)68-7)58-28-24-43(61)56-51(58)63)33-73-79(65,72-31-13-27-55)77-46-41(74-50(48(46)69-8)59-29-25-44(62)57-52(59)64)32-70-53(36-14-10-9-11-15-36,37-16-20-39(66-5)21-17-37)38-18-22-40(67-6)23-19-38/h9-11,14-25,28-29,34-35,41-42,45-50H,12-13,30-33H2,1-8H3,(H,56,61,63)(H,57,62,64)/t41-,42-,45-,46-,47-,48-,49-,50-,78?,79?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-U](pCyEt)[2'-O-Me-U-3'-cyanoethyl-Phosphoramidite]; UmUm; [5'-O-DMTr-2'-OMe-U](pCyEt)[2'-OMe-U-3'-CE Phosphoramidite]

[5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-O-Me-U-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-cytidine with an acetyl (Ac) protecting group, coupled with a 2'-O-Me-uridine. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01153

MF: C55H68N8O17P2

MF: 1175.14

Purity: ≥97% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: DBULUINHIAJRPG-AQFWJGNWSA-N

IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C55H68N8O17P2/c1-35(2)63(36(3)4)81(74-31-13-27-56)79-47-44(78-51(49(47)71-8)62-30-26-46(65)60-54(62)67)34-76-82(68,75-32-14-28-57)80-48-43(77-52(50(48)72-9)61-29-25-45(58-37(5)64)59-53(61)66)33-73-55(38-15-11-10-12-16-38,39-17-21-41(69-6)22-18-39)40-19-23-42(70-7)24-20-40/h10-12,15-26,29-30,35-36,43-44,47-52H,13-14,31-34H2,1-9H3,(H,60,65,67)(H,58,59,64,66)/t43-,44-,47-,48-,49-,50-,51-,52-,81?,82?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-C(acetyl)](pCyEt)[2'-O-Me-U-3'-cyanoethyl-Phosphoramidite]; CmUm; [5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-OMe-U-3'-CE Phosphoramidite]

[5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-guanosine with an isobutyryl (iBu) protecting group, coupled with a 2'-O-Me-guanosine also featuring an isobutyryl (iBu) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01154

MF: C63H79N13O17P2

MF: 1352.35

Purity: ≥95% by HPLC

Appearance: White to off-white powder

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InChIKey: MSQJFSFYPIFAMO-XXECTENDSA-N

IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C63H79N13O17P2/c1-36(2)55(77)70-61-68-53-47(57(79)72-61)66-34-74(53)59-51(84-11)49(92-94(87-30-16-28-64)76(38(5)6)39(7)8)46(91-59)33-89-95(81,88-31-17-29-65)93-50-45(90-60(52(50)85-12)75-35-67-48-54(75)69-62(73-58(48)80)71-56(78)37(3)4)32-86-63(40-18-14-13-15-19-40,41-20-24-43(82-9)25-21-41)42-22-26-44(83-10)27-23-42/h13-15,18-27,34-39,45-46,49-52,59-60H,16-17,30-33H2,1-12H3,(H2,68,70,72,77,79)(H2,69,71,73,78,80)/t45-,46-,49-,50-,51-,52-,59-,60-,94?,95?/m1/s1

Synonyms: [5'-O-DMTr-2'-OMe-G(iBu)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

[5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-uridine, coupled with a 2'-O-Me-guanosine featuring an isobutyryl (iBu) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01155

MF: C58H72N10O17P2

MF: 1243.21

Purity: ≥95% by HPLC

Appearance: White to off-white powder

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InChIKey: PJSNGMFTSNHPEB-DEECTFEXSA-N

IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C58H72N10O17P2/c1-35(2)52(70)64-56-63-51-46(53(71)65-56)61-34-67(51)55-49(76-9)47(84-86(79-30-14-27-59)68(36(3)4)37(5)6)44(83-55)33-81-87(73,80-31-15-28-60)85-48-43(82-54(50(48)77-10)66-29-26-45(69)62-57(66)72)32-78-58(38-16-12-11-13-17-38,39-18-22-41(74-7)23-19-39)40-20-24-42(75-8)25-21-40/h11-13,16-26,29,34-37,43-44,47-50,54-55H,14-15,30-33H2,1-10H3,(H,62,69,72)(H2,63,64,65,70,71)/t43-,44-,47-,48-,49-,50-,54-,55-,86?,87?/m1/s1

Synonyms: [5'-O-DMTr-2'-OMe-U](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

[5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]

Description: [5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite] is a modified nucleoside phosphoramidite used in oligonucleotide synthesis. It consists of a 5'-O-DMTr-2'-OMe-cytidine with an acetyl (Ac) protecting group, coupled with a 2'-O-Me-guanosine featuring an isobutyryl (iBu) protecting group. These modifications enhance the stability, binding specificity, and resistance to enzymatic degradation of the resulting oligonucleotides, making it valuable for biochemical research and therapeutic applications.

CAT: BRP-01156

MF: C60H75N11O17P2

MF: 1284.27

Purity: ≥95% by HPLC

Appearance: White to off-white powder

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InChIKey: JREOEYAVHNOKMM-UWSVYRINSA-N

IUPAC Name: (2R,3R,4R,5R)-2-((((((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphoryl)oxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C60H75N11O17P2/c1-36(2)54(73)67-58-66-53-48(55(74)68-58)63-35-70(53)57-51(79-10)49(87-89(82-31-15-28-61)71(37(3)4)38(5)6)46(86-57)34-84-90(76,83-32-16-29-62)88-50-45(85-56(52(50)80-11)69-30-27-47(64-39(7)72)65-59(69)75)33-81-60(40-17-13-12-14-18-40,41-19-23-43(77-8)24-20-41)42-21-25-44(78-9)26-22-42/h12-14,17-27,30,35-38,45-46,49-52,56-57H,15-16,31-34H2,1-11H3,(H,64,65,72,75)(H2,66,67,68,73,74)/t45-,46-,49-,50-,51-,52-,56-,57-,89?,90?/m1/s1

Synonyms: [5'-O-DMTr-2'-OMe-C(Ac)](pCyEt)[2'-O-Me-G(iBu)-3'-CE-Phosphoramidite]