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2'-Modified Phosphoramidites
(466/466) 2'-Phosphoramidites
(21/21) 3'-Modified Phosphoramidites
(186/186) 5'-Modified Phosphoramidites
(21/21) Arabino Phosphoramidites
(19/19) Base Protected Phosphoramidites (365/365) Dye Phosphoramidites
(53/53) Label Phosphoramidites
(82/82) Linker Phosphoramidites
(72/72) Other Phosphoramidites
(92/92) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(15/15) Spacer Phosphoramidites
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(466/466) 2'-Phosphoramidites
(21/21) 3'-Modified Phosphoramidites
(186/186) 5'-Modified Phosphoramidites
(21/21) Arabino Phosphoramidites
(19/19) Base Protected Phosphoramidites (365/365) Dye Phosphoramidites
(53/53) Label Phosphoramidites
(82/82) Linker Phosphoramidites
(72/72) Other Phosphoramidites
(92/92) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(15/15) Spacer Phosphoramidites
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-amidite.gif)
2'-OTBS 7De8a-A(dmf) amidite
Description: 2'-OTBS 7De8a-A(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of adenine residues modified with a 7-deaza-8-azaadenine (7De8a) nucleoside and protected with dimethylformamidine (dmf) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00890
MF: C49H67N8O7PSi
MF: 939.18
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: FFFMJLRLMAOUHM-NWPXMRGSSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(4-(((dimethylamino)methylene)amino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C49H67N8O7PSi/c1-34(2)57(35(3)4)65(61-29-17-28-50)63-43-42(31-60-49(36-18-15-14-16-19-36,37-20-24-39(58-10)25-21-37)38-22-26-40(59-11)27-23-38)62-47(44(43)64-66(12,13)48(5,6)7)56-46-41(30-54-56)45(51-32-52-46)53-33-55(8)9/h14-16,18-27,30,32-35,42-44,47H,17,29,31H2,1-13H3/t42-,43-,44-,47-,65?/m1/s1
Synonyms: 5'-O-DMT-2'-O-TBDMS 7De8a-A(dmf) 3'-CE Phosphoramidite
PHT PEG3 amidite
Description: PHT PEG3 amidite is a modified phosphoramidite used in oligonucleotide synthesis. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00891
CAS: 2170381-91-4
MF: C23H34N3O7P
MF: 495.51
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: UDTLXDXACDJZQQ-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(N(C(C)C)P(OCCC#N)OCCOCCOCCON(C(C1=C2C=CC=C1)=O)C2=O)C
IUPAC Name: 2-cyanoethyl (2-(2-(2-((1,3-dioxoisoindolin-2-yl)oxy)ethoxy)ethoxy)ethyl) diisopropylphosphoramidite
InChI: InChI=1S/C23H34N3O7P/c1-18(2)26(19(3)4)34(32-11-7-10-24)33-17-15-30-13-12-29-14-16-31-25-22(27)20-8-5-6-9-21(20)23(25)28/h5-6,8-9,18-19H,7,11-17H2,1-4H3
Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 2-[2-[2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]ethoxy]ethoxy]ethyl ester
PHT PEG4 amidite
Description: PHT PEG4 amidite is a modified phosphoramidite utilized in oligonucleotide synthesis. This compound is vital for the creation of oligonucleotides with tailored modifications, which find applications across molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00892
CAS: 539820-47-8
MF: C25H38N3O8P
MF: 539.57
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: GRCXVBYRTJTFCI-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCCOCCOCCOCCON1C(=O)C2=CC=CC=C2C1=O
IUPAC Name: 3-[2-[2-[2-[2-(1,3-dioxoisoindol-2-yl)oxyethoxy]ethoxy]ethoxy]ethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C25H38N3O8P/c1-20(2)28(21(3)4)37(35-11-7-10-26)36-19-17-33-15-13-31-12-14-32-16-18-34-27-24(29)22-8-5-6-9-23(22)25(27)30/h5-6,8-9,20-21H,7,11-19H2,1-4H3
Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 2-[2-[2-[2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]ethoxy]ethoxy]ethoxy]ethyl ester; 2-cyanoethyl (2-(2-(2-(2-((1,3-dioxoisoindolin-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethyl) diisopropylphosphoramidite
Cyanoethoxycarbonyl C6 amine amidite
Description: Cyanoethoxycarbonyl C6 amine amidite is a modified phosphoramidite used in oligonucleotide synthesis. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00893
CAS: 242147-85-9
MF: C19H35N4O4P
MF: 414.49
Purity: >98%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: OXPJJHKDHVDTKR-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)OCCC#N)OCCC#N
IUPAC Name: 2-cyanoethyl N-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]carbamate
InChI: InChI=1S/C19H35N4O4P/c1-17(2)23(18(3)4)28(27-16-10-12-21)26-15-8-6-5-7-13-22-19(24)25-14-9-11-20/h17-18H,5-10,13-16H2,1-4H3,(H,22,24)
Synonyms: 2-cyanoethyl (6-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)hexyl)carbamate
Cbz C2 amine amidite
Description: Cbz C2 amine amidite is a modified phosphoramidite used in oligonucleotide synthesis. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00894
CAS: 133339-58-9
MF: C19H30N3O4P
MF: 395.44
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: BFXBTPRPHVBFNA-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCCNC(=O)OCC1=CC=CC=C1
IUPAC Name: benzyl N-[2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyethyl]carbamate
InChI: InChI=1S/C19H30N3O4P/c1-16(2)22(17(3)4)27(25-13-8-11-20)26-14-12-21-19(23)24-15-18-9-6-5-7-10-18/h5-7,9-10,16-17H,8,12-15H2,1-4H3,(H,21,23)
Synonyms: 5-Oxa-2,7-diaza-6-phosphanonanoic acid, 6-(2-cyanoethoxy)-8-methyl-7-(1-methylethyl)-, phenylmethyl ester; benzyl (2-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)ethyl)carbamate
Cbz C6 amine amidite
Description: Cbz C6 amine amidite is a modified phosphoramidite used in oligonucleotide synthesis. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00895
CAS: 1235579-76-6
MF: C23H38N3O4P
MF: 451.55
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: DEWXQEGATRHNSP-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)OCC1=CC=CC=C1)OCCC#N
IUPAC Name: benzyl N-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]carbamate
InChI: InChI=1S/C23H38N3O4P/c1-20(2)26(21(3)4)31(30-18-12-15-24)29-17-11-6-5-10-16-25-23(27)28-19-22-13-8-7-9-14-22/h7-9,13-14,20-21H,5-6,10-12,16-19H2,1-4H3,(H,25,27)
Synonyms: 9-Oxa-2,11-diaza-10-phosphatridecanoic acid, 10-(2-cyanoethoxy)-12-methyl-11-(1-methylethyl)-, phenylmethyl ester; benzyl (6-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)hexyl)carbamate
Chloracetyl C6 amine amidite
Description: Chloracetyl C6 amine amidite is a modified phosphoramidite used in oligonucleotide synthesis. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00896
CAS: 220555-61-3
MF: C17H33ClN3O3P
MF: 393.90
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: LHDZYEHTVUMWHK-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)CCl)OCCC#N
IUPAC Name: 2-chloro-N-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]acetamide
InChI: InChI=1S/C17H33ClN3O3P/c1-15(2)21(16(3)4)25(24-13-9-10-19)23-12-8-6-5-7-11-20-17(22)14-18/h15-16H,5-9,11-14H2,1-4H3,(H,20,22)
Synonyms: 6-[(2-Chloroacetyl)amino]hexyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; 6-(2-chloroacetamido)hexyl (2-cyanoethyl) diisopropylphosphoramidite
amino-peg3-glycerin-amidite.gif)
O1-DMTr-O3-(Fmoc)amino-PEG3 Glycerin amidite
Description: O1-DMTr-O3-(Fmoc)amino-PEG3 Glycerin amidite is a modified phosphoramidite used in oligonucleotide synthesis. This compound enables the synthesis of oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00897
MF: C54H66N3O10P
MF: 948.11
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: VWAHQMAILUKYAF-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(N(C(C)C)P(OCCC#N)OC(COC(C1=CC=CC=C1)(C2=CC=C(OC)C=C2)C3=CC=C(OC)C=C3)COCCOCCOCCNC(OCC4C5=C(C=CC=C5)C6=C4C=CC=C6)=O)C
IUPAC Name: (9H-fluoren-9-yl)methyl (4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-1,1-bis(4-methoxyphenyl)-1-phenyl-2,6,9,12-tetraoxatetradecan-14-yl)carbamate
InChI: InChI=1S/C54H66N3O10P/c1-40(2)57(41(3)4)68(66-31-14-29-55)67-47(38-65-54(42-15-8-7-9-16-42,43-21-25-45(59-5)26-22-43)44-23-27-46(60-6)28-24-44)37-63-36-35-62-34-33-61-32-30-56-53(58)64-39-52-50-19-12-10-17-48(50)49-18-11-13-20-51(49)52/h7-13,15-28,40-41,47,52H,14,30-39H2,1-6H3,(H,56,58)
ANA 2'-OAc C(Ac) amidite
Description: ANA 2'-OAc C(Ac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues modified with 2'-O-acetyl and protected with acetyl (Ac) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00898
CAS: 373645-92-2
MF: C43H52N5O10P
MF: 829.89
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: JCLYEEIHQSPYLZ-ZDPTUIABSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3S,4R,5R)-2-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-3-yl acetate
InChI: InChI=1S/C43H52N5O10P/c1-28(2)48(29(3)4)59(55-26-12-24-44)58-39-37(57-41(40(39)56-31(6)50)47-25-23-38(45-30(5)49)46-42(47)51)27-54-43(32-13-10-9-11-14-32,33-15-19-35(52-7)20-16-33)34-17-21-36(53-8)22-18-34/h9-11,13-23,25,28-29,37,39-41H,12,26-27H2,1-8H3,(H,45,46,49,51)/t37-,39-,40+,41-,59?/m1/s1
Synonyms: N-[1-[2-O-Acetyl-5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-β-D-arabinofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]acetamide; 2'-OAc-C(Ac)-ANA-CE-Phosphoramidite; DMTr-2'-ara-OAc-C(Ac)-3'-CE-Phosphoramidite
ANA 2'-OMe C(Bz) amidite
Description: ANA 2'-OMe C(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues modified with 2'-O-methyl and protected with benzoyl (Bz) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00899
CAS: 373645-97-7
MF: C47H54N5O9P
MF: 863.95
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: JFFSFQRVIPPCBC-XBCOPKIOSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OC)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC
IUPAC Name: N-[1-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C47H54N5O9P/c1-32(2)52(33(3)4)62(59-30-14-28-48)61-42-40(60-45(43(42)57-7)51-29-27-41(50-46(51)54)49-44(53)34-15-10-8-11-16-34)31-58-47(35-17-12-9-13-18-35,36-19-23-38(55-5)24-20-36)37-21-25-39(56-6)26-22-37/h8-13,15-27,29,32-33,40,42-43,45H,14,30-31H2,1-7H3,(H,49,50,53,54)/t40-,42-,43+,45-,62?/m1/s1
Synonyms: (2R,3R,4S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; N-[1-[2-O-Methyl-5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-β-D-arabinofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide; 2'-OMe-C(Bz)-ANA-CE-Phosphoramidite; DMTr-2'-ara-OMe-C(Bz)-3'-CE-Phosphoramidite; 5'-O-DMTr-2'-ara-OMe-C(Bz)-3'-CE-Phosphoramidite; N4-benzoyl-(5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-arabinocytidine-3'-[(2-cyanoethyl)-(N,N-diisopropropyl)]-Phosphoramidite
ANA 2'-OMe G(iBu) amidite
Description: ANA 2'-OMe G(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of guanosine residues modified with 2'-O-methyl and protected with isobutyl (iBu) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00900
CAS: 1239669-74-9
MF: C45H56N7O9P
MF: 869.96
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: IRRDHRZUOZNWDJ-HHNCBLOXSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1OC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9)38(61-62(59-25-13-24-46)52(29(3)4)30(5)6)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39+,43-,62?/m1/s1
Synonyms: DMTr-2'-ara-OMe-G(iBu)-3'-CE-Phosphoramidite; 2'-OMe-G(iBu)-ANA-CE-Phosphoramidite; N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-arabinofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropanamide; 5'-O-DMTr-2'-ara-OMe-G(iBu)-3'-CE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-arabinoguanosine-3'-[(2-cyanoethyl)-(N,N-diisopropropyl)]-Phosphoramidite
ANA 2'-OMe U amidite
Description: ANA 2'-OMe U amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of uridine residues modified with 2'-O-methyl into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00901
CAS: 1239669-77-2
MF: C40H49N4O9P
MF: 760.83
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: UVUOJOLPNDCIHL-LYEFJPEKSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OC)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
IUPAC Name: 3-[[(2R,3R,4S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C40H49N4O9P/c1-27(2)44(28(3)4)54(51-25-11-23-41)53-36-34(52-38(37(36)49-7)43-24-22-35(45)42-39(43)46)26-50-40(29-12-9-8-10-13-29,30-14-18-32(47-5)19-15-30)31-16-20-33(48-6)21-17-31/h8-10,12-22,24,27-28,34,36-38H,11,25-26H2,1-7H3,(H,42,45,46)/t34-,36-,37+,38-,54?/m1/s1
Synonyms: 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-arabinofuranosyl]-2,4(1H,3H)-pyrimidinedione; 2'-OMe-U-ANA-CE-Phosphoramidite; (2R,3R,4S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5-O-(4,4'-dimethoxytrityl)-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1-deoxy-2-O-methyl-1-uracil-1-yl-beta-D-arabino-pentofuranose; DMTr-2'-ara-OMe-U-3'-CE-Phosphoramidite; 5'-O-DMTr-2'-ara-OMe-U-3'-CE-Phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-arabinouridine-3'-[(2-cyanoethyl)-(N,N-diisopropropyl)]-Phosphoramidite
ANA 2'-OMe A(Bz) amidite
Description: ANA 2'-OMe A(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of adenine residues modified with 2'-O-methyl and protected with benzoyl (Bz) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00902
CAS: 1239669-70-5
MF: C48H54N7O8P
MF: 887.98
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: AZCGOTUYEPXHMJ-VOJYYREFSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
IUPAC Name: N-[9-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C48H54N7O8P/c1-32(2)55(33(3)4)64(61-28-14-27-49)63-42-40(62-47(43(42)59-7)54-31-52-41-44(50-30-51-45(41)54)53-46(56)34-15-10-8-11-16-34)29-60-48(35-17-12-9-13-18-35,36-19-23-38(57-5)24-20-36)37-21-25-39(58-6)26-22-37/h8-13,15-26,30-33,40,42-43,47H,14,28-29H2,1-7H3,(H,50,51,53,56)/t40-,42-,43+,47-,64?/m1/s1
Synonyms: DMTr-2'-ara-OMe-A(Bz)-3'-CE-Phosphoramidite; 2'-OMe-A(Bz)-ANA-CE-Phosphoramidite; Benzamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-arabinofuranosyl]-9H-purin-6-yl]-; (2R,3R,4S,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMTr-2'-ara-OMe-A(Bz)-3'-CE-Phosphoramidite; N6-benzoyl-(5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-arabinoadenosine-3'-[(2-cyanoethyl)-(N, N-diisopropropyl)]-Phosphoramidite
aTNA A(Bz) amidite
Description: aTNA A(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00903
CAS: 1654757-57-9
MF: C48H55N8O7P
MF: 886.99
Purity: >98%
Appearance: White solid
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Storage: Store at -20 °C
InChIKey: IHMRCPNOGYPCLE-BZSGYPRQSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC(C)C(NC(=O)CN1C=NC=2C(=NC=NC21)NC(=O)C=3C=CC=CC3)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: (2R,3R)-3-(2-(6-benzamido-9H-purin-9-yl)acetamido)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)butan-2-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C48H55N8O7P/c1-33(2)56(34(3)4)64(62-28-14-27-49)63-35(5)42(53-43(57)29-55-32-52-44-45(50-31-51-46(44)55)54-47(58)36-15-10-8-11-16-36)30-61-48(37-17-12-9-13-18-37,38-19-23-40(59-6)24-20-38)39-21-25-41(60-7)26-22-39/h8-13,15-26,31-35,42H,14,28-30H2,1-7H3,(H,53,57)(H,50,51,54,58)/t35-,42-,64?/m1/s1
Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1R,2R)-2-[[2-[6-(benzoylamino)-9H-purin-9-yl]acetyl]amino]-3-[bis(4-methoxyphenyl)phenylmethoxy]-1-methylpropyl 2-cyanoethyl ester; (1R,2R)-2-[[2-[6-(Benzoylamino)-9H-purin-9-yl]acetyl]amino]-3-[bis(4-methoxyphenyl)phenylmethoxy]-1-methylpropyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite
2'-OTBS 5-I-C(Bz) amidite
Description: 2'-OTBS 5-I-C(Bz) amidite is used in the synthesis of oligonucleotides where specific modifications are required for various research or therapeutic applications. The iodine atom at the 5-position allows for further functionalization or labeling, the TBDMS group protects the 2'-hydroxyl during synthesis, and the benzoyl group protects the exocyclic amino group. This reagent is particularly useful in applications that demand modified nucleotides for enhanced properties such as increased stability or specific binding characteristics.
CAT: BRP-00907
CAS: 256493-91-1
MF: C52H65IN5O9PSi
MF: 1090.08
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: UVIALSKMICAVNV-ZQRHXHOESA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=C(C(=NC2=O)NC(=O)C3=CC=CC=C3)I)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-5-iodo-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C52H65IN5O9PSi/c1-35(2)58(36(3)4)68(64-32-18-31-54)66-45-44(34-63-52(38-21-16-13-17-22-38,39-23-27-41(61-8)28-24-39)40-25-29-42(62-9)30-26-40)65-49(46(45)67-69(10,11)51(5,6)7)57-33-43(53)47(56-50(57)60)55-48(59)37-19-14-12-15-20-37/h12-17,19-30,33,35-36,44-46,49H,18,32,34H2,1-11H3,(H,55,56,59,60)/t44-,45-,46-,49-,68?/m1/s1
Synonyms: Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-iodo-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-5-(4-benzamido-5-iodo-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5-Iodo Cytidine CED phosphoramidite; 5-Iodo 2'-TBDMS C(Bz) 3'-CE phosphoramidite
2'-OMe PseudoIsoCytidine(dmf) amidite
Description: 2'-OMe PseudoIsoCytidine(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of pseudoisocytidine modified with 2'-O-methyl and protected with dimethylformamidine (dmf) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as RNA research, antisense oligonucleotide design, and therapeutics.
CAT: BRP-00908
CAS: 141411-21-4
MF: C43H55N6O8P
MF: 814.92
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: SGBFUZIGEGJKFA-SAAFSQBVSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC1C(OC(C2=CN=C(N=CN(C)C)NC2=O)C1OC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-(((dimethylamino)methylene)amino)-6-oxo-1,6-dihydropyrimidin-5-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C43H55N6O8P/c1-29(2)49(30(3)4)58(55-25-13-24-44)57-39-37(56-38(40(39)53-9)36-26-45-42(47-41(36)50)46-28-48(5)6)27-54-43(31-14-11-10-12-15-31,32-16-20-34(51-7)21-17-32)33-18-22-35(52-8)23-19-33/h10-12,14-23,26,28-30,37-40H,13,25,27H2,1-9H3,(H,45,47,50)/t37-,38+,39-,40+,58?/m1/s1
Synonyms: Methanimidamide, N'-[5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-1,4-dihydro-4-oxo-2-pyrimidinyl]-N,N-dimethyl-; Phosphoramidous acid, bis(1-methylethyl)-, mono(2-cyanoethyl) ester, ester with N'-[5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-methyl-β-D-ribofuranosyl]-1,4-dihydro-4-oxo-2-pyrimidinyl]-N,N-dimethylmethanimidamide
2'-OTBS PseudoIsoCytidine(dmf) amidite
Description: 2'-OTBS PseudoIsoCytidine(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of pseudoisocytidine modified with a tert-butyldimethylsilyl (OTBS) protecting group and protected with dimethylformamidine (dmf) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as RNA research, antisense oligonucleotide design, and therapeutics.
CAT: BRP-00909
CAS: 1192344-93-6
MF: C48H67N6O8PSi
MF: 915.16
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: LSKHQLXTKWPBJC-LHBYQZGQSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC1C(OC(C2=CN=C(N=CN(C)C)NC2=O)C1O[Si](C)(C)C(C)(C)C)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2-(((dimethylamino)methylene)amino)-6-oxo-1,6-dihydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C48H67N6O8PSi/c1-33(2)54(34(3)4)63(59-29-17-28-49)61-43-41(60-42(44(43)62-64(12,13)47(5,6)7)40-30-50-46(52-45(40)55)51-32-53(8)9)31-58-48(35-18-15-14-16-19-35,36-20-24-38(56-10)25-21-36)37-22-26-39(57-11)27-23-37/h14-16,18-27,30,32-34,41-44H,17,29,31H2,1-13H3,(H,50,52,55)/t41-,42+,43-,44+,63?/m1/s1
Synonyms: Methanimidamide, N'-[5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-1,6-dihydro-6-oxo-2-pyrimidinyl]-N,N-dimethyl-; N'-[5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-1,6-dihydro-6-oxo-2-pyrimidinyl]-N,N-dimethylmethanimidamide
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Cyanine 3 amidite (iodide)
Description: Cyanine 3 amidite (iodide) is a fluorescent dye-labeled phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of Cyanine 3 (Cy3) fluorophore into the oligonucleotide sequence. This compound is widely used in various applications such as fluorescence in situ hybridization (FISH), microarray analysis, and fluorescence-based detection assays in molecular biology and diagnostics due to its strong and stable fluorescence properties.
CAT: BRP-00910
MF: C58H70IN4O4P
MF: 1045.10
Purity: >95%
Appearance: Dark-purple solid
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Storage: Store at -20 °C
InChIKey: GTLRVZNKJSCYOV-UHFFFAOYSA-M
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC1(C)C(C=CC=C2N(CCCOP(OCCC#N)N(C(C)C)C(C)C)C3=C(C=CC=C3)C2(C)C)=[N+](CCCOC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)C7=C1C=CC=C7.[I-]
IUPAC Name: 2-(3-(1-(3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)propyl)-3,3-dimethylindolin-2-ylidene)prop-1-en-1-yl)-1-(3-((4-methoxyphenyl)diphenylmethoxy)propyl)-3,3-dimethyl-3H-indol-1-ium;iodide
InChI: InChI=1S/C58H70N4O4P.HI/c1-44(2)62(45(3)4)67(65-42-21-38-59)66-43-23-40-61-53-31-19-17-29-51(53)57(7,8)55(61)33-20-32-54-56(5,6)50-28-16-18-30-52(50)60(54)39-22-41-64-58(46-24-12-10-13-25-46,47-26-14-11-15-27-47)48-34-36-49(63-9)37-35-48;/h10-20,24-37,44-45H,21-23,39-43H2,1-9H3;1H/q+1;/p-1
Synonyms: 3H-Indolium, 2-[3-[1-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1-propen-1-yl]-1-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-3,3-dimethyl-, iodide (1:1); Cyanine 3 amidite
Related CAS: 182873-76-3 (chloride) ; 718594-66-2 (free base)
ENA MeC(Bz) amidite
Description: ENA MeC(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as antisense technology, RNA research, and diagnostics.
CAT: BRP-00911
CAS: 287737-53-5
MF: C49H56N5O9P
MF: 889.99
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: ALWJTTIHWFLNHB-ABEMJPNPSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C4C(C(O3)(CCO4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[1-[(1R,5R,7R,8S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-8-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2,6-dioxabicyclo[3.2.1]octan-7-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C49H56N5O9P/c1-33(2)54(34(3)4)64(61-29-14-28-50)63-43-42-46(53-31-35(5)44(52-47(53)56)51-45(55)36-15-10-8-11-16-36)62-48(43,27-30-59-42)32-60-49(37-17-12-9-13-18-37,38-19-23-40(57-6)24-20-38)39-21-25-41(58-7)26-22-39/h8-13,15-26,31,33-34,42-43,46H,14,27,29-30,32H2,1-7H3,(H,51,52,55,56)/t42-,43+,46-,48-,64?/m1/s1
Synonyms: Benzamide, N-[1-[2,6-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5-deoxy-α-L-lyxo-hexofuranosyl]-1,2-dihydro-5-methyl-2-oxo-4-pyrimidinyl]-; ENA-5MeC (bz) Phosphoramidite; (1R,5R,7R,8S)-7-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2,6-dioxabicyclo[3.2.1]octan-8-yl (2-cyanoethyl) diisopropylphosphoramidite
-amidite.gif)
ENA MeC(dmf) amidite
Description: ENA MeC(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis. This compound is crucial for synthesizing oligonucleotides with ENA backbone modifications, which can impart enhanced stability and other properties for applications such as antisense technology, RNA research, and diagnostics.
CAT: BRP-00912
MF: C45H57N6O8P
MF: 840.96
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: UXKOVGOMMGRMCZ-GIEZTROHSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (1R,5R,7R,8S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-(4-(((dimethylamino)methylene)amino)-5-methyl-2-oxopyrimidin-1(2H)-yl)-2,6-dioxabicyclo[3.2.1]octan-8-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C45H57N6O8P/c1-31(2)51(32(3)4)60(57-26-13-25-46)59-40-39-42(50-28-33(5)41(48-43(50)52)47-30-49(6)7)58-44(40,24-27-55-39)29-56-45(34-14-11-10-12-15-34,35-16-20-37(53-8)21-17-35)36-18-22-38(54-9)23-19-36/h10-12,14-23,28,30-32,39-40,42H,13,24,26-27,29H2,1-9H3/t39-,40+,42-,44-,60?/m1/s1
Synonyms: ENA MeC(dmf) Phosphoramidite
