Phosphoramidites

2'-TFA-AE G(iBu) amidite

Description: 2'-TFA-AE G(iBu) amidite is a modified phosphoramidite utilized in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of guanine residues with 2'-trifluoroacetyl modification and isobutyl protection into the oligonucleotide sequence. This compound is valuable for synthesizing modified oligonucleotides for diverse applications in molecular biology, diagnostics, and therapeutics.

CAT: BRP-00856

CAS: 853748-79-5

Molecular Formula: C48H58F3N8O10P

Molecular Weight: 995.01

Purity: >95%

Appearance: Off-white solid

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InChIKey: XIQAQHLVRVPSFM-DYTYPCPCSA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCNC(=O)C(F)(F)F

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-[(2,2,2-trifluoroacetyl)amino]ethoxy]oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C48H58F3N8O10P/c1-29(2)42(60)56-46-55-41-38(43(61)57-46)54-28-58(41)44-40(65-26-24-53-45(62)48(49,50)51)39(69-70(67-25-12-23-52)59(30(3)4)31(5)6)37(68-44)27-66-47(32-13-10-9-11-14-32,33-15-19-35(63-7)20-16-33)34-17-21-36(64-8)22-18-34/h9-11,13-22,28-31,37,39-40,44H,12,24-27H2,1-8H3,(H,53,62)(H2,55,56,57,60,61)/t37-,39-,40-,44-,70?/m1/s1

Synonyms: (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-3,6-dihydro-9H-purin-9-yl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-O-(TFA-aminoethyl)-G(iBu) 3'-CE Phosphoramidite

2'-TFA-AE U amidite

Description: 2'-TFA-AE U amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of uracil residues with 2'-trifluoroacetyl modification into the oligonucleotide sequence. This compound is essential for synthesizing modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.

CAT: BRP-00857

CAS: 853748-56-8

Molecular Formula: C43H51F3N5O10P

Molecular Weight: 885.87

Purity: >95%

Appearance: Off-white solid

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InChIKey: YBHWJTBVGJAGKI-BVGHISPXSA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCNC(=O)C(F)(F)F)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: N-[2-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxyethyl]-2,2,2-trifluoroacetamide

InChI: InChI=1S/C43H51F3N5O10P/c1-28(2)51(29(3)4)62(59-25-10-22-47)61-37-35(60-39(50-24-21-36(52)49-41(50)54)38(37)57-26-23-48-40(53)43(44,45)46)27-58-42(30-11-8-7-9-12-30,31-13-17-33(55-5)18-14-31)32-15-19-34(56-6)20-16-32/h7-9,11-21,24,28-29,35,37-39H,10,23,25-27H2,1-6H3,(H,48,53)(H,49,52,54)/t35-,37-,38-,39-,62?/m1/s1

Synonyms: 5'-O-DMT-2'-O-(TFA-aminoethyl)-rU 3'-CE Phosphoramidite; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

2'-TFA-AE G(Ac) amidite

Description: 2'-TFA-AE G(Ac) amidite is a modified phosphoramidite employed in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of guanine residues with 2'-trifluoroacetyl modification and acetyl protection into the oligonucleotide sequence. This compound is crucial for synthesizing modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.

CAT: BRP-00858

CAS: 911110-89-9

Molecular Formula: C46H54F3N8O10P

Molecular Weight: 966.95

Purity: >95%

Appearance: Off-white solid

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InChIKey: MHPBJBUMRBEOBZ-DZAGQWDNSA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCNC(=O)C(F)(F)F)N2C=NC3=C2N=C(NC3=O)NC(=O)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

IUPAC Name: N-[2-[(2R,3R,4R,5R)-2-(2-acetamido-6-oxo-1H-purin-9-yl)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-3-yl]oxyethyl]-2,2,2-trifluoroacetamide

InChI: InChI=1S/C46H54F3N8O10P/c1-28(2)57(29(3)4)68(65-24-11-22-50)67-38-36(26-64-45(31-12-9-8-10-13-31,32-14-18-34(61-6)19-15-32)33-16-20-35(62-7)21-17-33)66-42(39(38)63-25-23-51-43(60)46(47,48)49)56-27-52-37-40(56)54-44(53-30(5)58)55-41(37)59/h8-10,12-21,27-29,36,38-39,42H,11,23-26H2,1-7H3,(H,51,60)(H2,53,54,55,58,59)/t36-,38-,39-,42-,68?/m1/s1

Synonyms: Guanosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[2-[(trifluoroacetyl)amino]ethyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-5-(2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-O-(TFA-aminoethyl)-G(Ac) 3'-CE Phosphoramidite

2'-TFA-AE MeC(Bz) amidite

Description: 2'-TFA-AE MeC(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 5-methylcytidine residues with 2'-trifluoroacetyl modification and benzoyl protection into the oligonucleotide sequence. This compound is essential for synthesizing modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.

CAT: BRP-00859

CAS: 911110-81-1

Molecular Formula: C51H58F3N6O10P

Molecular Weight: 1003.03

Purity: >95%

Appearance: Off-white solid

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InChIKey: SXKUHFATFPKDLA-DCGXNHRISA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCNC(=O)C(F)(F)F

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-[(2,2,2-trifluoroacetyl)amino]ethoxy]oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C51H58F3N6O10P/c1-33(2)60(34(3)4)71(68-29-14-27-55)70-43-42(32-67-50(37-17-12-9-13-18-37,38-19-23-40(64-6)24-20-38)39-21-25-41(65-7)26-22-39)69-47(44(43)66-30-28-56-48(62)51(52,53)54)59-31-35(5)45(58-49(59)63)57-46(61)36-15-10-8-11-16-36/h8-13,15-26,31,33-34,42-44,47H,14,28-30,32H2,1-7H3,(H,56,62)(H,57,58,61,63)/t42-,43-,44-,47-,71?/m1/s1

Synonyms: 5'-O-DMT-2'-O-(TFA-aminoethyl)-MeC(Bz) 3'-CE Phosphoramidite; (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

2'-(PHT)aminoethyl U amidite

Description: 2'-(PHT)aminoethyl U amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of uracil residues with a 2'-(PHT)aminoethyl modification into the oligonucleotide sequence. This compound is important for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.

CAT: BRP-00860

CAS: 1037523-39-9

Molecular Formula: C49H54N5O11P

Molecular Weight: 919.97

Purity: >95%

Appearance: Off-white solid

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InChIKey: VIVGUNXKRHKESW-FEVKEASNSA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCN2C(=O)C3=CC=CC=C3C2=O)N4C=CC(=O)NC4=O)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

IUPAC Name: 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-(1,3-dioxoisoindol-2-yl)ethoxy]-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C49H54N5O11P/c1-32(2)54(33(3)4)66(63-29-12-26-50)65-43-41(31-62-49(34-13-8-7-9-14-34,35-17-21-37(59-5)22-18-35)36-19-23-38(60-6)24-20-36)64-47(53-27-25-42(55)51-48(53)58)44(43)61-30-28-52-45(56)39-15-10-11-16-40(39)46(52)57/h7-11,13-25,27,32-33,41,43-44,47H,12,28-31H2,1-6H3,(H,51,55,58)/t41-,43-,44-,47-,66?/m1/s1

Synonyms: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-(PHT)aminoethyl-U 3'-CE Phosphoramidite

2'-MOE C(pac) amidite

Description: 2'-MOE C(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues with 2'-methoxyethyl (2'-MOE) modification and phenoxyacetyl (pac) protection into the oligonucleotide sequence. This compound is essential for synthesizing modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.

CAT: BRP-00861

Molecular Formula: C50H60N5O11P

Molecular Weight: 938.03

Purity: >95%

Appearance: Off-white solid

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InChIKey: UZRZIHOXKZDIFQ-KUTAVOKMSA-N

Solubility: Soluble in Acetonitrile, DMF

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)-5-(2-oxo-4-(2-phenoxyacetamido)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C50H60N5O11P/c1-35(2)55(36(3)4)67(64-30-14-28-51)66-46-43(33-63-50(37-15-10-8-11-16-37,38-19-23-40(59-6)24-20-38)39-21-25-41(60-7)26-22-39)65-48(47(46)61-32-31-58-5)54-29-27-44(53-49(54)57)52-45(56)34-62-42-17-12-9-13-18-42/h8-13,15-27,29,35-36,43,46-48H,14,30-34H2,1-7H3,(H,52,53,56,57)/t43-,46-,47-,48-,67?/m1/s1

Synonyms: 5'-O-DMT-2'-O-MOE-C(pac) 3'-CE Phosphoramidite

2'-MOE MeC(dmf) amidite

Description: 2'-MOE MeC(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of 2'-methoxyethyl (2'-MOE) modified cytidine residues with dimethylformamidine (dmf) protection into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.

CAT: BRP-00862

Molecular Formula: C46H61N6O9P

Molecular Weight: 873.00

Purity: >97%

Appearance: Off-white solid

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InChIKey: WUCVRRYJZTWUBS-XUMVYBCMSA-N

Solubility: Soluble in Acetonitrile, DMF

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-(((dimethylamino)methylene)amino)-5-methyl-2-oxopyrimidin-1(2H)-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C46H61N6O9P/c1-32(2)52(33(3)4)62(59-26-14-25-47)61-41-40(60-44(42(41)57-28-27-54-8)51-29-34(5)43(49-45(51)53)48-31-50(6)7)30-58-46(35-15-12-11-13-16-35,36-17-21-38(55-9)22-18-36)37-19-23-39(56-10)24-20-37/h11-13,15-24,29,31-33,40-42,44H,14,26-28,30H2,1-10H3/t40-,41-,42-,44-,62?/m1/s1

Synonyms: 5'-O-DMT-2'-O-MOE-MeC(dmf) 3'-CE Phosphoramidite

2'-MOE A(dmf) amidite

Description: 2'-MOE A(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 2'-methoxyethyl (2'-MOE) modified adenine residues with dimethylformamidine (dmf) protection into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.

CAT: BRP-00863

Molecular Formula: C46H59N8O8P

Molecular Weight: 883.00

Purity: >98%

Appearance: Off-white solid

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InChIKey: HNUYQNDVGXBRKT-GIDUWHSKSA-N

Solubility: Soluble in Acetonitrile, DMF

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-(((dimethylamino)methylene)amino)-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C46H59N8O8P/c1-32(2)54(33(3)4)63(60-25-13-24-47)62-41-39(61-45(42(41)58-27-26-55-7)53-31-50-40-43(51-30-52(5)6)48-29-49-44(40)53)28-59-46(34-14-11-10-12-15-34,35-16-20-37(56-8)21-17-35)36-18-22-38(57-9)23-19-36/h10-12,14-23,29-33,39,41-42,45H,13,25-28H2,1-9H3/t39-,41-,42-,45-,63?/m1/s1

Synonyms: 5'-O-DMT-2'-O-MOE-A(dmf) 3'-CE Phosphoramidite

2'-MOE A(pac) amidite

Description: 2'-MOE A(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of adenine residues modified with 2'-methoxyethyl (2'-MOE) and protected with phenoxyacetyl (pac) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.

CAT: BRP-00864

Molecular Formula: C51H60N7O10P

Molecular Weight: 962.05

Purity: >97%

Appearance: Off-white solid

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InChIKey: DGWJRMSFFQNJSR-UMSFVQQVSA-N

Solubility: Soluble in Acetonitrile, DMF

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C51H60N7O10P/c1-35(2)58(36(3)4)69(66-28-14-27-52)68-46-43(31-65-51(37-15-10-8-11-16-37,38-19-23-40(61-6)24-20-38)39-21-25-41(62-7)26-22-39)67-50(47(46)63-30-29-60-5)57-34-55-45-48(53-33-54-49(45)57)56-44(59)32-64-42-17-12-9-13-18-42/h8-13,15-26,33-36,43,46-47,50H,14,28-32H2,1-7H3,(H,53,54,56,59)/t43-,46-,47-,50-,69?/m1/s1

Synonyms: 5'-O-DMT-2'-O-MOE-A(pac) 3'-CE Phosphoramidite

2'-MOE MeC(pac) amidite

Description: 2'-MOE MeC(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues modified with 2'-methoxyethyl (2'-MOE) and protected with phenoxyacetyl (pac) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics,

CAT: BRP-00865

Molecular Formula: C51H62N5O11P

Molecular Weight: 952.06

Purity: >98%

Appearance: Off-white solid

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InChIKey: KQFFNZKJAGTJRO-VVFLMUEQSA-N

Solubility: Soluble in Acetonitrile, DMF

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)-5-(5-methyl-2-oxo-4-(2-phenoxyacetamido)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C51H62N5O11P/c1-35(2)56(36(3)4)68(65-29-15-28-52)67-46-44(33-64-51(38-16-11-9-12-17-38,39-20-24-41(60-7)25-21-39)40-22-26-42(61-8)27-23-40)66-49(47(46)62-31-30-59-6)55-32-37(5)48(54-50(55)58)53-45(57)34-63-43-18-13-10-14-19-43/h9-14,16-27,32,35-36,44,46-47,49H,15,29-31,33-34H2,1-8H3,(H,53,54,57,58)/t44-,46-,47-,49-,68?/m1/s1

Synonyms: 5'-O-DMT-2'-O-MOE-MeC(pac) 3'-CE Phosphoramidite

2'-MOE G(iPr-pac) amidite

Description: 2'-MOE G(iPr-pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of guanine residues modified with 2'-methoxyethyl (2'-MOE) and protected with isopropylphenoxyacetyl (iPr-pac) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.

CAT: BRP-00866

Molecular Formula: C54H66N7O11P

Molecular Weight: 1020.13

Purity: >95%

Appearance: Off-white solid

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InChIKey: HCOJSGDKIGGZGC-LZDPKHDJSA-N

Solubility: Soluble in Acetonitrile, DMF

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-(2-(4-isopropylphenoxy)acetamido)-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C54H66N7O11P/c1-35(2)38-16-22-44(23-17-38)68-33-46(62)57-53-58-50-47(51(63)59-53)56-34-60(50)52-49(67-31-30-64-7)48(72-73(70-29-13-28-55)61(36(3)4)37(5)6)45(71-52)32-69-54(39-14-11-10-12-15-39,40-18-24-42(65-8)25-19-40)41-20-26-43(66-9)27-21-41/h10-12,14-27,34-37,45,48-49,52H,13,29-33H2,1-9H3,(H2,57,58,59,62,63)/t45-,48-,49-,52-,73?/m1/s1

Synonyms: 5'-O-DMT-2'-O-MOE-G(iPr-pac) 3'-CE Phosphoramidite

2'-O-NMA A(Bz) amidite

Description: 2'-O-NMA A(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of adenine residues modified with 2'-O-(2-(methylamino)-2-oxoethyl) (NMA) and protected with benzoyl (Bz) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.

CAT: BRP-00867

CAS: 1025783-20-3

Molecular Formula: C50H57N8O9P

Molecular Weight: 945.03

Purity: >98%

Appearance: Off-white solid

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InChIKey: GEYNOJIHDLPUEX-GNUXOQNYSA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCC(=O)NC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-(methylamino)-2-oxoethoxy]oxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C50H57N8O9P/c1-33(2)58(34(3)4)68(65-28-14-27-51)67-44-41(29-64-50(36-17-12-9-13-18-36,37-19-23-39(61-6)24-20-37)38-21-25-40(62-7)26-22-38)66-49(45(44)63-30-42(59)52-5)57-32-55-43-46(53-31-54-47(43)57)56-48(60)35-15-10-8-11-16-35/h8-13,15-26,31-34,41,44-45,49H,14,28-30H2,1-7H3,(H,52,59)(H,53,54,56,60)/t41-,44-,45-,49-,68?/m1/s1

Synonyms: Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[2-(methylamino)-2-oxoethyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(methylamino)-2-oxoethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-DMT-2'-O-NMA-A(Bz)-3'-CE-Phosphoramidite; [6-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]adenosine]-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite

2'-O-NMA G(iBu) amidite

Description: 2'-O-NMA G(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of guanine residues modified with 2'-O-(2-(methylamino)-2-oxoethyl) (NMA) and protected with isobutyl (iBu) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.

CAT: BRP-00868

CAS: 1025783-22-5

Molecular Formula: C47H59N8O10P

Molecular Weight: 927.01

Purity: >98%

Appearance: Off-white solid

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InChIKey: BNLNDNDXCOPBTF-NCJSJSGWSA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCC(=O)NC

InChI: InChI=1S/C47H59N8O10P/c1-29(2)43(57)52-46-51-42-39(44(58)53-46)50-28-54(42)45-41(61-27-38(56)49-7)40(65-66(63-25-13-24-48)55(30(3)4)31(5)6)37(64-45)26-62-47(32-14-11-10-12-15-32,33-16-20-35(59-8)21-17-33)34-18-22-36(60-9)23-19-34/h10-12,14-23,28-31,37,40-41,45H,13,25-27H2,1-9H3,(H,49,56)(H2,51,52,53,57,58)/t37-,40-,41-,45-,66?/m1/s1

Synonyms: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[2-(methylamino)-2-oxoethyl]-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-(methylamino)-2-oxoethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-DMT-2'-O-NMA-G(iBu)-3'-CE-Phosphoramidite; [5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-2-N-isobutyrylguanosine]-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite

2'-O-NMA MeC(Bz) amidite

Description: 2'-O-NMA MeC(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues modified with 2'-O-(2-(methylamino)-2-oxoethyl) (NMA) and protected with benzoyl (Bz) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.

CAT: BRP-00869

CAS: 1025783-18-9

Molecular Formula: C50H59N6O10P

Molecular Weight: 935.03

Purity: >95%

Appearance: Off-white solid

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InChIKey: OABRWFIIVWCDDM-WBHVIXSUSA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=C(C(=NC2=O)NC(=O)C=3C=CC=CC3)C)C1OCC(=O)NC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C

IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(methylamino)-2-oxoethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C50H59N6O10P/c1-33(2)56(34(3)4)67(64-29-15-28-51)66-44-42(31-63-50(37-18-13-10-14-19-37,38-20-24-40(60-7)25-21-38)39-22-26-41(61-8)27-23-39)65-48(45(44)62-32-43(57)52-6)55-30-35(5)46(54-49(55)59)53-47(58)36-16-11-9-12-17-36/h9-14,16-27,30,33-34,42,44-45,48H,15,29,31-32H2,1-8H3,(H,52,57)(H,53,54,58,59)/t42-,44-,45-,48-,67?/m1/s1

Synonyms: Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-methyl-2'-O-[2-(methylamino)-2-oxoethyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-DMT-2'-O-NMA-5-Me-C(Bz)-3'-CE-Phosphoramidite

2'-OAlly A(Bz) amidite

Description: 2'-OAlly A(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of adenine residues modified with 2'-O-allyl and protected with benzoyl (Bz) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.

CAT: BRP-00870

CAS: 136834-09-8

Molecular Formula: C50H56N7O8P

Molecular Weight: 914.01

Purity: >95%

Appearance: Off-white solid

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InChIKey: PZHYXONYDRPFHJ-XOMUZYEBSA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCC=C)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-prop-2-enoxyoxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C50H56N7O8P/c1-8-29-61-45-44(65-66(63-30-15-28-51)57(34(2)3)35(4)5)42(64-49(45)56-33-54-43-46(52-32-53-47(43)56)55-48(58)36-16-11-9-12-17-36)31-62-50(37-18-13-10-14-19-37,38-20-24-40(59-6)25-21-38)39-22-26-41(60-7)27-23-39/h8-14,16-27,32-35,42,44-45,49H,1,15,29-31H2,2-7H3,(H,52,53,55,58)/t42-,44-,45-,49-,66?/m1/s1

Synonyms: (2R,3R,4R,5R)-4-(Allyloxy)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propenyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

2'-OAlly G(iBu) amidite

Description: 2'-OAlly G(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of guanine residues modified with 2'-O-allyl and protected with isobutyl (iBu) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.

CAT: BRP-00871

CAS: 163070-99-3

Molecular Formula: C47H58N7O9P

Molecular Weight: 896.00

Purity: >95%

Appearance: Off-white solid

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InChIKey: WZIZCXQOBBGIEA-VCGWOZLGSA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1OCC=C)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C

IUPAC Name: (2R,3R,4R,5R)-4-(allyloxy)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C47H58N7O9P/c1-10-26-59-41-40(63-64(61-27-14-25-48)54(31(4)5)32(6)7)38(62-45(41)53-29-49-39-42(53)50-46(52-44(39)56)51-43(55)30(2)3)28-60-47(33-15-12-11-13-16-33,34-17-21-36(57-8)22-18-34)35-19-23-37(58-9)24-20-35/h10-13,15-24,29-32,38,40-41,45H,1,14,26-28H2,2-9H3,(H2,50,51,52,55,56)/t38-,40-,41-,45-,64?/m1/s1

Synonyms: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-2-propenyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

2'-OAlly U amidite

Description: 2'-OAlly U amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of uracil residues modified with 2'-O-allyl into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.

CAT: BRP-00872

CAS: 171486-64-9

Molecular Formula: C42H51N4O9P

Molecular Weight: 786.86

Purity: >95%

Appearance: Off-white solid

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InChIKey: PRCRTSIDLZWSDO-CYSIDSPMSA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCC=C)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-prop-2-enoxyoxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C42H51N4O9P/c1-8-26-51-39-38(55-56(53-27-12-24-43)46(29(2)3)30(4)5)36(54-40(39)45-25-23-37(47)44-41(45)48)28-52-42(31-13-10-9-11-14-31,32-15-19-34(49-6)20-16-32)33-17-21-35(50-7)22-18-33/h8-11,13-23,25,29-30,36,38-40H,1,12,26-28H2,2-7H3,(H,44,47,48)/t36-,38-,39-,40-,56?/m1/s1

Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propenyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-4-(allyloxy)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5-O-(4,4'-dimethoxytrityl)-2-O-allyl-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1-deoxy-1-uracil-1-yl-beta-D-ribo-pentofuranose

2'-OTBS MeC(pac) amidite

Description: 2'-OTBS MeC(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues modified with 2'-O-tert-butyldimethylsilyl (2'-OTBS) and protected with phenoxyacetyl (pac) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.

CAT: BRP-00873

Molecular Formula: C54H70N5O10PSi

Molecular Weight: 1008.24

Purity: >95%

Appearance: Off-white solid

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InChIKey: HKKHIMPFWSYKJT-XCUKYXTNSA-N

Solubility: Soluble in Acetonitrile, DMF

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(5-methyl-2-oxo-4-(2-phenoxyacetamido)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C54H70N5O10PSi/c1-37(2)59(38(3)4)70(66-33-19-32-55)68-48-46(35-65-54(40-20-15-13-16-21-40,41-24-28-43(62-9)29-25-41)42-26-30-44(63-10)31-27-42)67-51(49(48)69-71(11,12)53(6,7)8)58-34-39(5)50(57-52(58)61)56-47(60)36-64-45-22-17-14-18-23-45/h13-18,20-31,34,37-38,46,48-49,51H,19,33,35-36H2,1-12H3,(H,56,57,60,61)/t46-,48-,49-,51-,70?/m1/s1

Synonyms: 5'-O-DMT-2'-O-TBDMS-5-Me-C(pac) 3'-CE Phosphoramidite

2'-OPivOM U amidite

Description: 2'-O-PivOM U amidite is a specialized nucleotide for oligonucleotide synthesis, featuring a pivaloyloxymethyl (PivOM) group protecting the 2'-hydroxyl group of uridine. This modification enhances stability during synthesis and can be removed under mild acidic conditions post-synthesis. The amidite functionality allows for the stepwise addition of this nucleotide in solid-phase synthesis, making it essential for creating RNA molecules with specific modifications for research and therapeutic applications.

CAT: BRP-00874

CAS: 1097131-15-1

Molecular Formula: C45H57N4O11P

Molecular Weight: 860.94

Purity: >95%

Appearance: Off-white solid

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InChIKey: CWFIVBQKXNPXJJ-WXSPLRIASA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCOC(=O)C(C)(C)C)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: [(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxymethyl 2,2-dimethylpropanoate

InChI: InChI=1S/C45H57N4O11P/c1-30(2)49(31(3)4)61(58-27-13-25-46)60-39-37(59-41(48-26-24-38(50)47-43(48)52)40(39)55-29-56-42(51)44(5,6)7)28-57-45(32-14-11-10-12-15-32,33-16-20-35(53-8)21-17-33)34-18-22-36(54-9)23-19-34/h10-12,14-24,26,30-31,37,39-41H,13,27-29H2,1-9H3,(H,47,50,52)/t37-,39-,40-,41-,61?/m1/s1

Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(2,2-dimethyl-1-oxopropoxy)methyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)oxy)methyl pivalate; 2'-O-PivOM-5'-O-DMT-Uridine 3'-CEP

2'-OPivOM C(Ac) amidite

Description: 2'-O-PivOM C(Ac) amidite is a modified cytidine nucleotide used in oligonucleotide synthesis. It features a 2'-O-pivaloyloxymethyl group protecting the 2'-hydroxyl and an acetyl group protecting the amino group at the 4-position, facilitating stepwise addition during solid-phase synthesis. This allows for the creation of RNA molecules with specific modifications.

CAT: BRP-00875

CAS: 1097131-18-4

Molecular Formula: C47H60N5O11P

Molecular Weight: 902.00

Purity: >95%

Appearance: Off-white solid

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InChIKey: XGSYTNZPEKBGAM-JFALYFJISA-N

Solubility: Soluble in Acetonitrile, DMF

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCOC(=O)C(C)(C)C)N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: [(2R,3R,4R,5R)-2-(4-acetamido-2-oxopyrimidin-1-yl)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-3-yl]oxymethyl 2,2-dimethylpropanoate

InChI: InChI=1S/C47H60N5O11P/c1-31(2)52(32(3)4)64(61-28-14-26-48)63-41-39(62-43(42(41)58-30-59-44(54)46(6,7)8)51-27-25-40(49-33(5)53)50-45(51)55)29-60-47(34-15-12-11-13-16-34,35-17-21-37(56-9)22-18-35)36-19-23-38(57-10)24-20-36/h11-13,15-25,27,31-32,39,41-43H,14,28-30H2,1-10H3,(H,49,50,53,55)/t39-,41-,42-,43-,64?/m1/s1

Synonyms: Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(2,2-dimethyl-1-oxopropoxy)methyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (((2R,3R,4R,5R)-2-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-3-yl)oxy)methyl pivalate; 2'-O-PivOM-5'-O-DMT-Cytidine (N-Ac) 3'-CEP

2'-TFA-AE G(iBu) amidite

2'-TFA-AE U amidite

2'-TFA-AE G(Ac) amidite

2'-TFA-AE MeC(Bz) amidite

2'-(PHT)aminoethyl U amidite

2'-MOE C(pac) amidite

2'-MOE MeC(dmf) amidite

2'-MOE A(dmf) amidite

2'-MOE A(pac) amidite

2'-MOE MeC(pac) amidite

2'-MOE G(iPr-pac) amidite

2'-O-NMA A(Bz) amidite

2'-O-NMA G(iBu) amidite

2'-O-NMA MeC(Bz) amidite

2'-OAlly A(Bz) amidite

2'-OAlly G(iBu) amidite

2'-OAlly U amidite

2'-OTBS MeC(pac) amidite

2'-OPivOM U amidite

2'-OPivOM C(Ac) amidite

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