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Phosphoramidites

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2'-Modified Phosphoramidites
(535/535) 2'-Phosphoramidites
(27/27) 3'-Modified Phosphoramidites
(201/201) 5'-Modified Phosphoramidites
(34/34) Arabino Phosphoramidites
(24/24) Base Protected Phosphoramidites (423/423) Dye Phosphoramidites
(64/64) Label Phosphoramidites
(81/81) Linker Phosphoramidites
(91/91) Other Phosphoramidites
(93/93) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(25/25) Spacer Phosphoramidites
(24/24)
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PMO I(NPE) Monomer

Description: PMO I(NPE) monomer refers to a monomeric unit used in the synthesis of Phosphorodiamidate Morpholino Oligomers (PMOs). PMOs are synthetic nucleic acid analogs used in antisense therapy and molecular biology research. The ''I(NPE)'' modification provides unique properties to the PMO, such as enhanced binding affinity or stability, and it can be used to target specific RNA sequences for therapeutic or research purposes.
CAT: BRP-00836
Molecular Formula: C39H39ClN7O6P
Molecular Weight: 768.21
Purity: >98%
Appearance: Yellow solid
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Storage: Store at -20 °C
InChIKey: FQWVICSCUXDSJM-SSGMMMFMSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: ((2S,6R)-6-(6-(4-nitrophenethoxy)-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate
InChI: InChI=1S/C39H39ClN7O6P/c1-44(2)54(40,50)52-26-34-24-45(39(30-12-6-3-7-13-30,31-14-8-4-9-15-31)32-16-10-5-11-17-32)25-35(53-34)46-28-43-36-37(46)41-27-42-38(36)51-23-22-29-18-20-33(21-19-29)47(48)49/h3-21,27-28,34-35H,22-26H2,1-2H3/t34-,35+,54?/m0/s1

(R)-SNA MeC(Bz) amidite

Description: (R)-SNA MeC(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It is used to introduce SNA backbone modifications and benzoyl-protected cytidine residues during solid-phase oligonucleotide synthesis. SNA modifications can enhance the stability and binding affinity of oligonucleotides, and benzoyl protection allows selective deprotection under mild conditions.
CAT: BRP-00837
Molecular Formula: C47H55N6O8P
Molecular Weight: 862.97
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: INDCRCPSOKWLRY-CEEWGNETSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (R)-2-(2-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)acetamido)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C47H55N6O8P/c1-33(2)53(34(3)4)62(60-28-14-27-48)61-32-40(49-43(54)30-52-29-35(5)44(51-46(52)56)50-45(55)36-15-10-8-11-16-36)31-59-47(37-17-12-9-13-18-37,38-19-23-41(57-6)24-20-38)39-21-25-42(58-7)26-22-39/h8-13,15-26,29,33-34,40H,14,28,30-32H2,1-7H3,(H,49,54)(H,50,51,55,56)/t40-,62?/m1/s1
Synonyms: (R)-SNA C(Bz) amidite; (R)-SNA 5-Me-C(Bz) amidite

(R)-SNA G(iBu) amidite

Description: (R)-SNA G(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It is used to introduce SNA backbone modifications and isobutyl-protected guanosine residues during solid-phase oligonucleotide synthesis. SNA modifications can enhance the stability and binding affinity of oligonucleotides, and isobutyl protection allows selective deprotection under mild conditions.
CAT: BRP-00838
Molecular Formula: C44H55N8O8P
Molecular Weight: 854.95
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: GIZOJVPZHAXHBF-KGRUAYADSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (R)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-2-(2-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)acetamido)propyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C44H55N8O8P/c1-29(2)41(54)49-43-48-40-39(42(55)50-43)46-28-51(40)25-38(53)47-35(27-60-61(59-24-12-23-45)52(30(3)4)31(5)6)26-58-44(32-13-10-9-11-14-32,33-15-19-36(56-7)20-16-33)34-17-21-37(57-8)22-18-34/h9-11,13-22,28-31,35H,12,24-27H2,1-8H3,(H,47,53)(H2,48,49,50,54,55)/t35-,61?/m1/s1
Related CAS: 1280548-97-1 (S-isomer)

LNA I amidite

Description: LNA I amidite is a phosphoramidite used in oligonucleotide synthesis to introduce LNA (Locked Nucleic Acid) modifications containing an inosine (I) nucleobase. LNA modifications enhance the stability and binding affinity of oligonucleotides to their complementary RNA or DNA strands. LNA I amidite allows for the synthesis of oligonucleotides containing inosine-modified LNA residues, which can be useful in various molecular biology applications, including antisense therapy, RNA structural studies, and gene expression modulation.
CAT: BRP-00839
Molecular Formula: C41H47N6O8P
Molecular Weight: 782.84
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: JVTYXZHEHLVHJW-NKXPIFMZSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C2C(OC1(CO2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)N6C=NC7=C6N=CNC7=O
IUPAC Name: 3-[[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-(6-oxo-1H-purin-9-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C41H47N6O8P/c1-27(2)47(28(3)4)56(53-22-10-21-42)55-36-35-39(46-26-45-34-37(46)43-25-44-38(34)48)54-40(36,23-51-35)24-52-41(29-11-8-7-9-12-29,30-13-17-32(49-5)18-14-30)31-15-19-33(50-6)20-16-31/h7-9,11-20,25-28,35-36,39H,10,22-24H2,1-6H3,(H,43,44,48)/t35-,36+,39-,40-,56?/m1/s1
Synonyms: (1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(6-oxo-1,6-dihydro-9H-purin-9-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite

2'-MOE MeC(Ac) OMe-amidite

Description: 2'-MOE MeC(Ac) OMe-amidite is a modified phosphoramidite used in oligonucleotide synthesis to introduce 2'-methoxyethyl (2'-MOE) modifications into cytidine (C) residues. 2'-MOE MeC(Ac) OMe-amidite is crucial for the controlled synthesis of modified oligonucleotides, which find applications in molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00840
Molecular Formula: C43H57N4O10P
Molecular Weight: 820.92
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: FKPROVDGFNABNE-KZQAAKLLSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-5-(4-acetamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl methyl diisopropylphosphoramidite
InChI: InChI=1S/C43H57N4O10P/c1-28(2)47(29(3)4)58(53-10)57-38-37(56-41(39(38)54-25-24-50-7)46-26-30(5)40(44-31(6)48)45-42(46)49)27-55-43(32-14-12-11-13-15-32,33-16-20-35(51-8)21-17-33)34-18-22-36(52-9)23-19-34/h11-23,26,28-29,37-39,41H,24-25,27H2,1-10H3,(H,44,45,48,49)/t37-,38-,39-,41-,58?/m1/s1

1-DMTr-2-propanediyl amidite

Description: 1-DMTr-2-propanediyl amidite is a phosphoramidite used in oligonucleotide synthesis. It serves as a spacer moiety during solid-phase oligonucleotide synthesis, allowing for the attachment of nucleotide building blocks to a growing oligonucleotide chain. 1-DMTr-2-propanediyl amidite plays a crucial role in the efficient and controlled synthesis of oligonucleotides for various applications in molecular biology and biotechnology.
CAT: BRP-00841
Molecular Formula: C33H43N2O5P
Molecular Weight: 578.69
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: XCLJWHBPKOARSH-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC(C)COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC
IUPAC Name: 3-[1-[bis(4-methoxyphenyl)-phenylmethoxy]propan-2-yloxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C33H43N2O5P/c1-25(2)35(26(3)4)41(39-23-11-22-34)40-27(5)24-38-33(28-12-9-8-10-13-28,29-14-18-31(36-6)19-15-29)30-16-20-32(37-7)21-17-30/h8-10,12-21,25-27H,11,23-24H2,1-7H3
Synonyms: 1-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite

LNA MeC(pac) amidite

Description: LNA MeC(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis to introduce Locked Nucleic Acid (LNA) modifications containing a methylated cytidine (MeC) base with a phenoxyacetyl (pac) protecting group. LNA MeC(pac) amidite allows for the synthesis of oligonucleotides containing LNA modifications with methylated cytidine residues, which can be useful in various molecular biology applications, including gene expression modulation and RNA targeting.
CAT: BRP-00842
Molecular Formula: C49H56N5O10P
Molecular Weight: 905.99
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: PRARYIAJOKFQRQ-MJKSTTCNSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(5-methyl-2-oxo-4-(2-phenoxyacetamido)pyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C49H56N5O10P/c1-33(2)54(34(3)4)65(62-28-14-27-50)64-44-43-46(53-29-35(5)45(52-47(53)56)51-42(55)30-59-41-17-12-9-13-18-41)63-48(44,31-60-43)32-61-49(36-15-10-8-11-16-36,37-19-23-39(57-6)24-20-37)38-21-25-40(58-7)26-22-38/h8-13,15-26,29,33-34,43-44,46H,14,28,30-32H2,1-7H3,(H,51,52,55,56)/t43-,44+,46-,48-,65?/m1/s1
Synonyms: LNA-5-Me-C(pac) CE-Phosphoramidite; DMTr-LNA-5MeC(pac)-3-CED-phosphoramidite

MMTr PEG3 amidite

Description: MMTr PEG3 amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a linker during solid-phase oligonucleotide synthesis, allowing for the attachment of nucleotide building blocks to a growing oligonucleotide chain with the flexibility provided by the PEG3 linker. MMTr PEG3 amidite plays a crucial role in the efficient and controlled synthesis of oligonucleotides for various applications in molecular biology and biotechnology, particularly when flexibility or spacing is desired.
CAT: BRP-00843
Molecular Formula: C35H47N2O6P
Molecular Weight: 622.74
Purity: >95%
Appearance: Colourless oily matter
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Storage: Store at -20 °C
InChIKey: FUFCVFZHFJGQTH-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OCCOCCOCCOC(C(C=C1)=CC=C1OC)(C2=CC=CC=C2)C3=CC=CC=C3)N(C(C)C)C(C)C
IUPAC Name: 2-cyanoethyl (2-(2-(2-((4-methoxyphenyl)diphenylmethoxy)ethoxy)ethoxy)ethyl) diisopropylphosphoramidite
InChI: InChI=1S/C35H47N2O6P/c1-29(2)37(30(3)4)44(42-22-12-21-36)43-28-26-40-24-23-39-25-27-41-35(31-13-8-6-9-14-31,32-15-10-7-11-16-32)33-17-19-34(38-5)20-18-33/h6-11,13-20,29-30H,12,22-28H2,1-5H3

LNA MeC(dmf) amidite

Description: LNA MeC(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis to introduce Locked Nucleic Acid (LNA) modifications containing a methylated cytidine (MeC) base with a dimethylformamidine (dmf) protecting group. LNA MeC(dmf) amidite allows for the synthesis of oligonucleotides containing LNA modifications with methylated cytidine residues, which can be useful in various molecular biology applications, including gene expression modulation and RNA targeting.
CAT: BRP-00844
Molecular Formula: C44H55N6O8P
Molecular Weight: 826.93
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: ALMLYLOSIBVJJH-JHFWARBRSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(4-(((dimethylamino)methylene)amino)-5-methyl-2-oxopyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C44H55N6O8P/c1-30(2)50(31(3)4)59(56-25-13-24-45)58-39-38-41(49-26-32(5)40(47-42(49)51)46-29-48(6)7)57-43(39,27-54-38)28-55-44(33-14-11-10-12-15-33,34-16-20-36(52-8)21-17-34)35-18-22-37(53-9)23-19-35/h10-12,14-23,26,29-31,38-39,41H,13,25,27-28H2,1-9H3/t38-,39+,41-,43-,59?/m1/s1
Synonyms: LNA-5-Me-C(dmf) CE-Phosphoramidite; DMTr-LNA-5MeC(dmf)-3-CED-phosphoramidite

LNA A(dmf) amidite

Description: LNA A(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis to introduce Locked Nucleic Acid (LNA) modifications containing a dimethylformamidine (dmf) protecting group on adenine (A) nucleobase. LNA A(dmf) amidite allows for the synthesis of oligonucleotides containing LNA modifications with adenine residues protected by dimethylformamidine, which can be useful in various molecular biology applications, including gene expression modulation and RNA targeting.
CAT: BRP-00845
Molecular Formula: C44H53N8O7P
Molecular Weight: 836.93
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: VCQRTYMXOYNMDL-IPPGHXGVSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(6-(((dimethylamino)methylene)amino)-9H-purin-9-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C44H53N8O7P/c1-30(2)52(31(3)4)60(57-24-12-23-45)59-39-38-42(51-29-48-37-40(49-28-50(5)6)46-27-47-41(37)51)58-43(39,25-55-38)26-56-44(32-13-10-9-11-14-32,33-15-19-35(53-7)20-16-33)34-17-21-36(54-8)22-18-34/h9-11,13-22,27-31,38-39,42H,12,24-26H2,1-8H3/t38-,39+,42-,43-,60?/m1/s1
Synonyms: LNA A(dmf) CE-Phosphoramidite; DMTr-LNA-A(dmf)-3-CED-phosphoramidite

MMTr C3 amine amidite

Description: MMTr C3 amine amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a linker during solid-phase oligonucleotide synthesis, allowing for the attachment of nucleotide building blocks to a growing oligonucleotide chain. MMTr C3 amine amidite plays a crucial role in the efficient and controlled synthesis of oligonucleotides for various applications in molecular biology and biotechnology.
CAT: BRP-00846
CAS: 119462-97-4
Molecular Formula: C32H42N3O3P
Molecular Weight: 547.68
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: ZDCIPDOLNLJZRB-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCNC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=C(C=C3)OC)OCCC#N
IUPAC Name: 3-[[di(propan-2-yl)amino]-[3-[[(4-methoxyphenyl)-diphenylmethyl]amino]propoxy]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C32H42N3O3P/c1-26(2)35(27(3)4)39(37-24-12-22-33)38-25-13-23-34-32(28-14-8-6-9-15-28,29-16-10-7-11-17-29)30-18-20-31(36-5)21-19-30/h6-11,14-21,26-27,34H,12-13,23-25H2,1-5H3
Synonyms: 2-Cyanoethyl 3-[[(4-methoxyphenyl)diphenylmethyl]amino]propyl N,N-bis(1-methylethyl)phosphoramidite; 2-cyanoethyl (3-(((4-methoxyphenyl)diphenylmethyl)amino)propyl) diisopropylphosphoramidite; MMTr C3 linker Phosphoramidite; Monomethoxytrityl-propylamine-linker Phosphoramidite

(S)-BuNA U amidite

Description: (S)-BuNA U amidite is a modified phosphoramidite used in oligonucleotide synthesis. It is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00847
CAS: 1452390-83-8
Molecular Formula: C38H47N4O7P
Molecular Weight: 702.79
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: GMUTXDAJRYBBQH-NMIPJSAASA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC(CN1C=CC(=O)NC1=O)CCOC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N(C(C)C)C(C)C
IUPAC Name: (S)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-1-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)butan-2-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C38H47N4O7P/c1-28(2)42(29(3)4)50(48-25-10-23-39)49-35(27-41-24-21-36(43)40-37(41)44)22-26-47-38(30-11-8-7-9-12-30,31-13-17-33(45-5)18-14-31)32-15-19-34(46-6)20-16-32/h7-9,11-21,24,28-29,35H,10,22,25-27H2,1-6H3,(H,40,43,44)/t35-,50?/m0/s1
Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S)-3-[bis(4-methoxyphenyl)phenylmethoxy]-1-[(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methyl]propyl 2-cyanoethyl ester; (1S)-3-[Bis(4-methoxyphenyl)phenylmethoxy]-1-[(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methyl]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite

(S)-BuNA C(Bz) amidite

Description: (S)-BuNA C(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00848
CAS: 1452390-96-3
Molecular Formula: C45H52N5O7P
Molecular Weight: 805.91
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: OZJXSCDXPZBOPH-ONFVIWAESA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC(CCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)CN4C=CC(=NC4=O)NC(=O)C5=CC=CC=C5
IUPAC Name: N-[1-[(2S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxybutyl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C45H52N5O7P/c1-33(2)50(34(3)4)58(56-30-13-28-46)57-41(32-49-29-26-42(48-44(49)52)47-43(51)35-14-9-7-10-15-35)27-31-55-45(36-16-11-8-12-17-36,37-18-22-39(53-5)23-19-37)38-20-24-40(54-6)25-21-38/h7-12,14-26,29,33-34,41H,13,27,30-32H2,1-6H3,(H,47,48,51,52)/t41-,58?/m0/s1
Synonyms: (S)-1-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)butan-2-yl (2-cyanoethyl) diisopropylphosphoramidite

(S)-BuNA A(Bz) amidite

Description: (S)-BuNA A(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00849
CAS: 1452390-99-6
Molecular Formula: C46H52N7O6P
Molecular Weight: 829.94
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: QOLFEXISLSPHKS-CTHPAJCMSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC(CCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)CN4C=NC5=C(N=CN=C54)NC(=O)C6=CC=CC=C6
IUPAC Name: N-[9-[(2S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxybutyl]purin-6-yl]benzamide
InChI: InChI=1S/C46H52N7O6P/c1-33(2)53(34(3)4)60(58-28-13-27-47)59-41(30-52-32-50-42-43(48-31-49-44(42)52)51-45(54)35-14-9-7-10-15-35)26-29-57-46(36-16-11-8-12-17-36,37-18-22-39(55-5)23-19-37)38-20-24-40(56-6)25-21-38/h7-12,14-25,31-34,41H,13,26,28-30H2,1-6H3,(H,48,49,51,54)/t41-,60?/m0/s1
Synonyms: (S)-1-(6-benzamido-9H-purin-9-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)butan-2-yl (2-cyanoethyl) diisopropylphosphoramidite

(S)-BuNA G(iBu) amidite

Description: (S)-BuNA G(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00850
Molecular Formula: C43H54N7O7P
Molecular Weight: 811.92
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: JDXNYQOHJJNIOS-BVARLVFGSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2CC(CCOC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxybutyl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C43H54N7O7P/c1-29(2)40(51)47-42-46-39-38(41(52)48-42)45-28-49(39)27-37(57-58(56-25-12-24-44)50(30(3)4)31(5)6)23-26-55-43(32-13-10-9-11-14-32,33-15-19-35(53-7)20-16-33)34-17-21-36(54-8)22-18-34/h9-11,13-22,28-31,37H,12,23,25-27H2,1-8H3,(H2,46,47,48,51,52)/t37-,58?/m0/s1
Synonyms: (S)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-1-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)butan-2-yl (2-cyanoethyl) diisopropylphosphoramidite

3'-O-Me-U-2'-phosphoramidite

Description: 3'-O-Me-U-2'-phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 3'-O-methyluridine residues into the oligonucleotide sequence. 3'-O-Me-U-2'-phosphoramidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00851
CAS: 179479-05-1
Molecular Formula: C40H49N4O9P
Molecular Weight: 760.83
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: FPRLFGWVAXFXTL-XKZJCBTISA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OC
IUPAC Name: 3-[[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-2-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C40H49N4O9P/c1-27(2)44(28(3)4)54(51-25-11-23-41)53-37-36(49-7)34(52-38(37)43-24-22-35(45)42-39(43)46)26-50-40(29-12-9-8-10-13-29,30-14-18-32(47-5)19-15-30)31-16-20-33(48-6)21-17-31/h8-10,12-22,24,27-28,34,36-38H,11,25-26H2,1-7H3,(H,42,45,46)/t34-,36-,37-,38-,54?/m1/s1
Synonyms: 3'-OMe U 2'-amidite; 5'-O-(4,4'-Dimethoxytrityl)-3'-O-methyl-uridine-2'-cyanoethyl phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-DMTr-3'-O-methyluridine-2'-CED-phosphoramidite; 3'-OMe-U Phosphoramidite; 5'-O-DMTr-3'-O-methyluridine-3'-CED-phosphoramidite; 3'-O-Methyl Uridine CED phosphoramidite

3'-O-Me-C(Ac)-2'-phosphoramidite

Description: 3'-O-Me-C(Ac)-2'-phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 3'-O-methylcytidine residues with acetyl protection into the oligonucleotide sequence. 3'-O-Me-C(Ac)-2'-phosphoramidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00852
Molecular Formula: C42H52N5O9P
Molecular Weight: 801.88
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: GATGWWGSSVDAEU-UAQIPLLRSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OC
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C42H52N5O9P/c1-28(2)47(29(3)4)57(54-26-12-24-43)56-39-38(52-8)36(55-40(39)46-25-23-37(44-30(5)48)45-41(46)49)27-53-42(31-13-10-9-11-14-31,32-15-19-34(50-6)20-16-32)33-17-21-35(51-7)22-18-33/h9-11,13-23,25,28-29,36,38-40H,12,26-27H2,1-8H3,(H,44,45,48,49)/t36-,38-,39-,40-,57?/m1/s1
Synonyms: (2R,3R,4R,5R)-2-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 3'-OMe C(Ac) 2'-amidite; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methyl-cytidine-2'-cyanoethyl phosphoramidite; 3'-OMe-C(Ac) Phosphoramidite

3'-O-Me-C(Bz)-2'-phosphoramidite

Description: 3'-O-Me-C(Bz)-2'-phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 3'-O-methylcytidine residues with benzoyl protection into the oligonucleotide sequence. 3'-O-Me-C(Bz)-2'-phosphoramidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00853
CAS: 179479-03-9
Molecular Formula: C47H54N5O9P
Molecular Weight: 863.95
Purity: >95%
Appearance: Off-white solid
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InChIKey: BENGZEFYMXNUAR-VKBHKTMGSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OC
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C47H54N5O9P/c1-32(2)52(33(3)4)62(59-30-14-28-48)61-43-42(57-7)40(60-45(43)51-29-27-41(50-46(51)54)49-44(53)34-15-10-8-11-16-34)31-58-47(35-17-12-9-13-18-35,36-19-23-38(55-5)24-20-36)37-21-25-39(56-6)26-22-37/h8-13,15-27,29,32-33,40,42-43,45H,14,30-31H2,1-7H3,(H,49,50,53,54)/t40-,42-,43-,45-,62?/m1/s1
Synonyms: 3'-OMe C(Bz) 2'-amidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N4-Bz-5'-O-DMTr-3'-O-methylcytidine-2'-CED-phosphoramidite; 3'-O-Methyl Cytidine (n-bz) CED phosphoramidite

3'-O-Me-G(iBu)-2'-phosphoramidite

Description: 3'-O-Me-G(iBu)-2'-phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 3'-O-methylguanosine residues with isobutyl protection into the oligonucleotide sequence. 3'-O-Me-G(iBu)-2'-phosphoramidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00854
CAS: 179479-04-0
Molecular Formula: C45H56N7O9P
Molecular Weight: 869.96
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: POYXHFZLQWXZTI-MLLDKZSOSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(61-62(59-25-13-24-46)52(29(3)4)30(5)6)38(57-9)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/m1/s1
Synonyms: 3'-OMe G(iBu) 2'-amidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-DMTr-N2-iso-butyroyl-3'-O-methylguanosine-2'-CED-phosphoramidite; 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)guanosine, 2'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylguanosine-2'-cyanoethyl phosphoramidite; 3'-O-Methyl Guanosine (n-ibu) CED phosphoramidite

2'-TFA-AE A(iBu) amidite

Description: 2'-TFA-AE A(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of adenine residues with 2'-trifluoroacetyl modification and isobutyl protection into the oligonucleotide sequence. 2'-TFA-AE A(iBu) amidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00855
CAS: 853748-67-1
Molecular Formula: C48H58F3N8O9P
Molecular Weight: 979.01
Purity: >95%
Appearance: Off-white solid
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InChIKey: PDBNCRNDNUXWIB-KUGYPCBWSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCNC(=O)C(F)(F)F
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-[(2,2,2-trifluoroacetyl)amino]ethoxy]oxolan-2-yl]purin-6-yl]-2-methylpropanamide
InChI: InChI=1S/C48H58F3N8O9P/c1-30(2)44(60)57-42-39-43(55-28-54-42)58(29-56-39)45-41(64-26-24-53-46(61)48(49,50)51)40(68-69(66-25-12-23-52)59(31(3)4)32(5)6)38(67-45)27-65-47(33-13-10-9-11-14-33,34-15-19-36(62-7)20-16-34)35-17-21-37(63-8)22-18-35/h9-11,13-22,28-32,38,40-41,45H,12,24-27H2,1-8H3,(H,53,61)(H,54,55,57,60)/t38-,40-,41-,45-,69?/m1/s1
Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-[2-[(trifluoroacetyl)amino]ethyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-isobutyramido-9H-purin-9-yl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-O-(TFA-aminoethyl)-A(iBu) 3'-CE Phosphoramidite
* Only for research. Not suitable for any diagnostic or therapeutic use.

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