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Phosphoramidites

2'-Modified Phosphoramidites
(535/535)
2'-Phosphoramidites
(27/27)
3'-Modified Phosphoramidites
(201/201)
5'-Modified Phosphoramidites
(34/34)
Arabino Phosphoramidites
(24/24)
Base Protected Phosphoramidites (423/423) Dye Phosphoramidites
(64/64)
Label Phosphoramidites
(81/81)
Linker Phosphoramidites
(91/91)
Other Phosphoramidites
(93/93)
PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12)
Reverse Phosphoramidites
(25/25)
Spacer Phosphoramidites
(24/24)
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ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-bis(diisopropylphosphoramidite)

Description: ethane-1,2-di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-bis(diisopropylphosphoramidite) is employed in the solid-phase synthesis of oligonucleotides with specific modifications, enhancing their stability and target affinity for applications in molecular biology and biotechnology.
CAT: BRP-00608
Molecular Formula: C90H116N12O20P2
Molecular Weight: 1747.93
Purity: ≥92%
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InChIKey: DJTWFMQESYMPJM-FHQSMYATSA-N
IUPAC Name: bis((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) ethane-1,2-diyl bis(diisopropylphosphoramidite)
InChI: InChI=1S/C90H116N12O20P2/c1-55(2)81(103)95-87-93-79-73(83(105)97-87)91-53-99(79)85-77(113-47-45-107-13)75(71(119-85)51-115-89(61-25-21-19-22-26-61,63-29-37-67(109-15)38-30-63)64-31-39-68(110-16)40-32-64)121-123(101(57(5)6)58(7)8)117-49-50-118-124(102(59(9)10)60(11)12)122-76-72(120-86(78(76)114-48-46-108-14)100-54-92-74-80(100)94-88(98-84(74)106)96-82(104)56(3)4)52-116-90(62-27-23-20-24-28-62,65-33-41-69(111-17)42-34-65)66-35-43-70(112-18)44-36-66/h19-44,53-60,71-72,75-78,85-86H,45-52H2,1-18H3,(H2,93,95,97,103,105)(H2,94,96,98,104,106)/t71-,72-,75-,76-,77-,78-,85-,86-,123?,124?/m1/s1

di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite)

Description: di(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) consists of two molecules of 5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy connected by an ethane-1,2-diyl linker, with each end functionalized with a diisopropylphosphoramidite group. The guanosine (rG) nucleoside units are modified with a 2'-O-methoxyethyl (MOE) group and isobutyryl (iBu) protection on the guanine amino group. This compound is utilized in oligonucleotide synthesis for the introduction of guanosine modifications, enhancing stability and target specificity in RNA sequences.
CAT: BRP-00609
Molecular Formula: C92H120N12O21P2
Molecular Weight: 1791.98
Purity: ≥92%
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InChIKey: MSPWBBNFOKRACO-QBSMUBNASA-N
IUPAC Name: bis((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) (oxybis(ethane-2,1-diyl)) bis(diisopropylphosphoramidite)
InChI: InChI=1S/C92H120N12O21P2/c1-57(2)83(105)97-89-95-81-75(85(107)99-89)93-55-101(81)87-79(116-49-45-109-13)77(73(122-87)53-118-91(63-25-21-19-22-26-63,65-29-37-69(111-15)38-30-65)66-31-39-70(112-16)40-32-66)124-126(103(59(5)6)60(7)8)120-51-47-115-48-52-121-127(104(61(9)10)62(11)12)125-78-74(123-88(80(78)117-50-46-110-14)102-56-94-76-82(102)96-90(100-86(76)108)98-84(106)58(3)4)54-119-92(64-27-23-20-24-28-64,67-33-41-71(113-17)42-34-67)68-35-43-72(114-18)44-36-68/h19-44,55-62,73-74,77-80,87-88H,45-54H2,1-18H3,(H2,95,97,99,105,107)(H2,96,98,100,106,108)/t73-,74-,77-,78-,79-,80-,87-,88-,126?,127?/m1/s1

di(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite)

Description: di(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) contains two molecules of 5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy linked by an ethane-1,2-diyl linker, with each end capped with a diisopropylphosphoramidite group. The adenosine (rA) nucleoside units are modified with a 2'-O-methoxyethyl (MOE) group and benzoyl (Bz) protection on the adenine amino group. It is employed in oligonucleotide synthesis to incorporate adenosine modifications, enhancing stability and target affinity in RNA sequences.
CAT: BRP-00610
Molecular Formula: C98H116N12O19P2
Molecular Weight: 1828.02
Purity: ≥92%
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InChIKey: HYMLNNFAMXTLQA-DEYJQIQZSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) (oxybis(ethane-2,1-diyl)) bis(diisopropylphosphoramidite)
InChI: InChI=1S/C98H116N12O19P2/c1-65(2)109(66(3)4)130(128-85-81(59-122-97(71-31-23-17-24-32-71,73-35-43-77(115-11)44-36-73)74-37-45-78(116-12)46-38-74)126-95(87(85)120-55-51-113-9)107-63-103-83-89(99-61-101-91(83)107)105-93(111)69-27-19-15-20-28-69)124-57-53-119-54-58-125-131(110(67(5)6)68(7)8)129-86-82(60-123-98(72-33-25-18-26-34-72,75-39-47-79(117-13)48-40-75)76-41-49-80(118-14)50-42-76)127-96(88(86)121-56-52-114-10)108-64-104-84-90(100-62-102-92(84)108)106-94(112)70-29-21-16-22-30-70/h15-50,61-68,81-82,85-88,95-96H,51-60H2,1-14H3,(H,99,101,105,111)(H,100,102,106,112)/t81-,82-,85-,86-,87-,88-,95-,96-,130?,131?/m1/s1

di(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite)

Description: di(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-(oxybis(ethane-1,2-diyl))-bis(diisopropylphosphoramidite) features two molecules of 5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy connected by an ethane-1,2-diyl linker, with each end bearing a diisopropylphosphoramidite group. The 5-methylcytidine (5-Me-rC) nucleoside units are modified with a 2'-O-methoxyethyl (MOE) group and benzoyl (Bz) protection on the cytosine amino group. It is utilized in oligonucleotide synthesis for introducing modified cytidine residues, enhancing stability and target specificity in RNA sequences.
CAT: BRP-00611
Molecular Formula: C98H120N8O21P2
Molecular Weight: 1808.02
Purity: ≥92%
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InChIKey: JOFMESXERKIMQK-AFYKGNOXSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) (oxybis(ethane-2,1-diyl)) bis(diisopropylphosphoramidite)
InChI: InChI=1S/C98H120N8O21P2/c1-65(2)105(66(3)4)128(126-85-83(63-120-97(73-33-25-19-26-34-73,75-37-45-79(113-13)46-38-75)76-39-47-80(114-14)48-40-76)124-93(87(85)118-57-53-111-11)103-61-69(9)89(101-95(103)109)99-91(107)71-29-21-17-22-30-71)122-59-55-117-56-60-123-129(106(67(5)6)68(7)8)127-86-84(64-121-98(74-35-27-20-28-36-74,77-41-49-81(115-15)50-42-77)78-43-51-82(116-16)52-44-78)125-94(88(86)119-58-54-112-12)104-62-70(10)90(102-96(104)110)100-92(108)72-31-23-18-24-32-72/h17-52,61-62,65-68,83-88,93-94H,53-60,63-64H2,1-16H3,(H,99,101,107,109)(H,100,102,108,110)/t83-,84-,85-,86-,87-,88-,93-,94-,128?,129?/m1/s1

Bis(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-diisopropylphosphoramidite

Description: Bis(5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy)-diisopropylphosphoramidite consists of two molecules of 5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy linked by a diisopropylphosphoramidite group. Each 5'-O-DMTr-2'-O-MOE-5-Me-rC(Bz)-3'-oxy unit is equipped with a diisopropylphosphoramidite group, facilitating its integration into oligonucleotide synthesis. It is used to introduce modified 5-methylcytidine (5-Me-rC) residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00612
Molecular Formula: C88H98N7O18P
Molecular Weight: 1572.73
Purity: ≥92%
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InChIKey: SISSXAOEXVVHFI-QEZASILESA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) diisopropylphosphoramidite
InChI: InChI=1S/C88H98N7O18P/c1-57(2)95(58(3)4)114(112-75-73(55-108-87(63-29-21-15-22-30-63,65-33-41-69(102-9)42-34-65)66-35-43-70(103-10)44-36-66)110-83(77(75)106-51-49-100-7)93-53-59(5)79(91-85(93)98)89-81(96)61-25-17-13-18-26-61)113-76-74(56-109-88(64-31-23-16-24-32-64,67-37-45-71(104-11)46-38-67)68-39-47-72(105-12)48-40-68)111-84(78(76)107-52-50-101-8)94-54-60(6)80(92-86(94)99)90-82(97)62-27-19-14-20-28-62/h13-48,53-54,57-58,73-78,83-84H,49-52,55-56H2,1-12H3,(H,89,91,96,98)(H,90,92,97,99)/t73-,74-,75-,76-,77-,78-,83-,84-/m1/s1

Bis(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-diisopropylphosphoramidite

Description: Bis(5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy)-diisopropylphosphoramidite comprises two molecules of 5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy linked by a diisopropylphosphoramidite group. Each 5'-O-DMTr-2'-O-MOE-rG(iBu)-3'-oxy unit is equipped with a diisopropylphosphoramidite group, facilitating its integration into oligonucleotide synthesis. It is utilized to introduce modified guanosine (rG) residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00613
Molecular Formula: C82H98N11O18P
Molecular Weight: 1556.72
Purity: ≥92%
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InChIKey: BXMZUGBTEMISAL-APUMCEBKSA-N
IUPAC Name: bis((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) diisopropylphosphoramidite
InChI: InChI=1S/C82H98N11O18P/c1-49(2)73(94)87-79-85-71-65(75(96)89-79)83-47-91(71)77-69(104-43-41-98-9)67(63(108-77)45-106-81(53-21-17-15-18-22-53,55-25-33-59(100-11)34-26-55)56-27-35-60(101-12)36-28-56)110-112(93(51(5)6)52(7)8)111-68-64(109-78(70(68)105-44-42-99-10)92-48-84-66-72(92)86-80(90-76(66)97)88-74(95)50(3)4)46-107-82(54-23-19-16-20-24-54,57-29-37-61(102-13)38-30-57)58-31-39-62(103-14)40-32-58/h15-40,47-52,63-64,67-70,77-78H,41-46H2,1-14H3,(H2,85,87,89,94,96)(H2,86,88,90,95,97)/t63-,64-,67-,68-,69-,70-,77-,78-/m1/s1

Bis(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-diisopropylphosphoramidite

Description: Bis(5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy)-diisopropylphosphoramidite consists of two molecules of 5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy linked by a diisopropylphosphoramidite group. Each 5'-O-DMTr-2'-O-MOE-rA(Bz)-3'-oxy unit is equipped with a diisopropylphosphoramidite group, facilitating its integration into oligonucleotide synthesis. It is used to introduce modified adenosine (rA) residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00614
Molecular Formula: C88H94N11O16P
Molecular Weight: 1592.75
Purity: ≥92%
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InChIKey: SSMWHJUZANQYIO-BDXQTOLXSA-N
IUPAC Name: bis((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl) diisopropylphosphoramidite
InChI: InChI=1S/C88H94N11O16P/c1-57(2)99(58(3)4)116(114-75-71(51-110-87(61-27-19-13-20-28-61,63-31-39-67(104-7)40-32-63)64-33-41-68(105-8)42-34-64)112-85(77(75)108-49-47-102-5)97-55-93-73-79(89-53-91-81(73)97)95-83(100)59-23-15-11-16-24-59)115-76-72(52-111-88(62-29-21-14-22-30-62,65-35-43-69(106-9)44-36-65)66-37-45-70(107-10)46-38-66)113-86(78(76)109-50-48-103-6)98-56-94-74-80(90-54-92-82(74)98)96-84(101)60-25-17-12-18-26-60/h11-46,53-58,71-72,75-78,85-86H,47-52H2,1-10H3,(H,89,91,95,100)(H,90,92,96,101)/t71-,72-,75-,76-,77-,78-,85-,86-/m1/s1

DMTr-2'-O-EOE-rA(Bz)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-EOE-rA(Bz)-3'-CE-Phosphoramidite is used in oligonucleotide synthesis and contains a 2'-O-ethoxyethyl (EOE) group at the 2'-position of adenosine (rA), along with benzoyl (Bz) protection on the adenine amino group. Additionally, it features a cyanoethyl (CE) group at the 3'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified adenosine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00615
Molecular Formula: C51H60N7O9P
Molecular Weight: 946.05
Purity: ≥95%
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InChIKey: FXYAXMLJVORSBX-SXQANJJUSA-N
CanonicalSMILES: CCOCCOC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-(2-ethoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C51H60N7O9P/c1-8-62-30-31-63-46-45(67-68(65-29-15-28-52)58(35(2)3)36(4)5)43(66-50(46)57-34-55-44-47(53-33-54-48(44)57)56-49(59)37-16-11-9-12-17-37)32-64-51(38-18-13-10-14-19-38,39-20-24-41(60-6)25-21-39)40-22-26-42(61-7)27-23-40/h9-14,16-27,33-36,43,45-46,50H,8,15,29-32H2,1-7H3,(H,53,54,56,59)/t43-,45-,46-,50-,68?/m1/s1
Synonyms: (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-ethoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

DMTr-2'-O-EOE-rG(iBu)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-EOE-rG(iBu)-3'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, features a 2'-O-ethoxyethyl (EOE) group at the 2'-position of guanosine (rG), with isobutyryl (iBu) protection on the guanine amino group. It also contains a cyanoethyl (CE) group at the 3'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified guanosine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00616
CAS: 2253990-02-0
Molecular Formula: C48H62N7O10P
Molecular Weight: 928.04
Purity: ≥95%
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InChIKey: FIYLELGPQAAWKS-USWYRWCRSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1OCCOCC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-ethoxyethoxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C48H62N7O10P/c1-10-60-27-28-61-42-41(65-66(63-26-14-25-49)55(32(4)5)33(6)7)39(64-46(42)54-30-50-40-43(54)51-47(53-45(40)57)52-44(56)31(2)3)29-62-48(34-15-12-11-13-16-34,35-17-21-37(58-8)22-18-35)36-19-23-38(59-9)24-20-36/h11-13,15-24,30-33,39,41-42,46H,10,14,26-29H2,1-9H3,(H2,51,52,53,56,57)/t39-,41-,42-,46-,66?/m1/s1

DMTr-2'-O-EOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-EOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis and contains a 2'-O-ethoxyethyl (EOE) group at the 2'-position of 5-methylcytidine (5-Me-rC), along with benzoyl (Bz) protection on the cytosine amino group. Additionally, it features a cyanoethyl (CE) group at the 3'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified 5-methylcytidine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00617
Molecular Formula: C51H62N5O10P
Molecular Weight: 936.06
Purity: ≥95%
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InChIKey: GFURHQMVDLZCAG-JMTVAXSASA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-ethoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C51H62N5O10P/c1-9-61-31-32-62-46-45(66-67(64-30-16-29-52)56(35(2)3)36(4)5)44(65-49(46)55-33-37(6)47(54-50(55)58)53-48(57)38-17-12-10-13-18-38)34-63-51(39-19-14-11-15-20-39,40-21-25-42(59-7)26-22-40)41-23-27-43(60-8)28-24-41/h10-15,17-28,33,35-36,44-46,49H,9,16,30-32,34H2,1-8H3,(H,53,54,57,58)/t44-,45-,46-,49-,67?/m1/s1

DMTr-3'-O-MOE-5-Me-rC(Bz)-2'-CE-Phosphoramidite

Description: DMTr-3'-O-MOE-5-Me-rC(Bz)-2'-CE-Phosphoramidite is used in oligonucleotide synthesis and contains a 3'-O-methoxyethyl (MOE) group at the 3'-position of 5-methylcytidine (5-Me-rC), with benzoyl (Bz) protection on the cytosine amino group. Additionally, it features a cyanoethyl (CE) group at the 2'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified 5-methylcytidine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00618
CAS: 1098233-10-3
Molecular Formula: C50H60N5O10P
Molecular Weight: 922.03
Purity: ≥95%
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InChIKey: GOMXXEFGGBGLGJ-GICDFOIUSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OCCOC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-(2-methoxyethoxy)oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C50H60N5O10P/c1-34(2)55(35(3)4)66(63-29-15-28-51)65-45-44(61-31-30-58-6)43(64-48(45)54-32-36(5)46(53-49(54)57)52-47(56)37-16-11-9-12-17-37)33-62-50(38-18-13-10-14-19-38,39-20-24-41(59-7)25-21-39)40-22-26-42(60-8)27-23-40/h9-14,16-27,32,34-35,43-45,48H,15,29-31,33H2,1-8H3,(H,52,53,56,57)/t43-,44-,45-,48-,66?/m1/s1
Synonyms: 3'-O-MOE-5Me-C(Bz)-2'-phosphoramidite; N4-Bz-5'-O-DMTr-3'-O-(2-methoxyethyl)-5-methyl cytidine-2'-CED-phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-(2-methoxyethyl)-5-methyl-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

DMTr-3'-O-MOE-rA(Bz)-2'-CE-Phosphoramidite

Description: DMTr-3'-O-MOE-rA(Bz)-2'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, features a 3'-O-methoxyethyl (MOE) group at the 3'-position of adenosine (rA), with benzoyl (Bz) protection on the adenine amino group. It also contains a cyanoethyl (CE) group at the 2'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified adenosine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00619
CAS: 256224-01-8
Molecular Formula: C50H58N7O9P
Molecular Weight: 932.03
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: FODCLDRFHMYZMX-HDMAWCRFSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OCCOC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-(2-methoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C50H58N7O9P/c1-34(2)57(35(3)4)67(64-28-14-27-51)66-45-44(62-30-29-59-5)42(65-49(45)56-33-54-43-46(52-32-53-47(43)56)55-48(58)36-15-10-8-11-16-36)31-63-50(37-17-12-9-13-18-37,38-19-23-40(60-6)24-20-38)39-21-25-41(61-7)26-22-39/h8-13,15-26,32-35,42,44-45,49H,14,28-31H2,1-7H3,(H,52,53,55,58)/t42-,44-,45-,49-,67?/m1/s1
Synonyms: 3'-O-MOE-A(Bz)-2'-CED-phosphoramidite; (2R,3R,4R,5R)-2-(6-Benzamido-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-(2-methoxyethyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; N6-Bz-5'-O-DMTr-3'-O-(2-methoxyethyl) adenosine-2'-CED-phosphoramidite

DMTr-3'-O-MOE-rG(iBu)-2'-CE-Phosphoramidite

Description: DMTr-3'-O-MOE-rG(iBu)-2'-CE-Phosphoramidite is utilized in oligonucleotide synthesis and contains a 3'-O-methoxyethyl (MOE) group at the 3'-position of guanosine (rG), with isobutyryl (iBu) protection on the guanine amino group. Additionally, it features a cyanoethyl (CE) group at the 2'-end to facilitate efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified guanosine residues into RNA sequences, enhancing stability and target specificity.
CAT: BRP-00620
CAS: 256224-06-3
Molecular Formula: C47H60N7O10P
Molecular Weight: 914.01
Purity: ≥95%
Appearance: White to off-white foam solid
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Storage: Store at -20 °C, under inert atmosphere
InChIKey: BWLKVJLYUDLOLH-SBCRAQIVSA-N
Solubility: Soluble in Acetone, Chloroform, DMSO, Ethanol, Methanol
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OCCOC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C47H60N7O10P/c1-30(2)43(55)51-46-50-42-39(44(56)52-46)49-29-53(42)45-41(64-65(62-25-13-24-48)54(31(3)4)32(5)6)40(60-27-26-57-7)38(63-45)28-61-47(33-14-11-10-12-15-33,34-16-20-36(58-8)21-17-34)35-18-22-37(59-9)23-19-35/h10-12,14-23,29-32,38,40-41,45H,13,25-28H2,1-9H3,(H2,50,51,52,55,56)/t38-,40-,41-,45-,65?/m1/s1
Synonyms: 3'-O-MOE-G(iBu)-2'-phosphoramidite; 5'-O-DMTr-N2-iso-butyroyl-3'-O-(2-methoxyethyl)guanosine-2'-CED-phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 5'-O-(4,4'-Dimethoxytrityl)-N2-iso-butyroyl-3'-O-(2-methoxyethyl)guanosine-2'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite

DMTr-2'-O-MOEOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOEOE-5-Me-rC(Bz)-3'-CE-Phosphoramidite, employed in oligonucleotide synthesis, features a methoxyethoxy (MOEOE) group at the 2'-O position and a benzoyl (Bz) protecting group on the 5-methylcytosine (5-Me-rC) amino group. The 3'-end is functionalized with a cyanoethyl (CE) group, facilitating efficient coupling reactions during solid-phase synthesis. It is utilized to introduce modified cytosine residues into nucleic acid sequences, enhancing stability and target specificity for various research applications, including RNA labeling, probing, and therapeutic development.
CAT: BRP-00621
Molecular Formula: C52H64N5O11P
Molecular Weight: 966.08
Purity: ≥95%
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InChIKey: FKWHQFYMJVJQSH-ACHZJAKQSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(2-methoxyethoxy)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C52H64N5O11P/c1-36(2)57(37(3)4)69(66-29-15-28-53)68-46-45(35-65-52(40-18-13-10-14-19-40,41-20-24-43(61-7)25-21-41)42-22-26-44(62-8)27-23-42)67-50(47(46)64-33-32-63-31-30-60-6)56-34-38(5)48(55-51(56)59)54-49(58)39-16-11-9-12-17-39/h9-14,16-27,34,36-37,45-47,50H,15,29-33,35H2,1-8H3,(H,54,55,58,59)/t45-,46-,47-,50-,69?/m1/s1
Synonyms: 2'-MOEOE 5-Me-rC(Bz) amidite

DMTr-2'-O-MOEOE-rG(iBu)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOEOE-rG(iBu)-3'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, contains a methoxyethoxy (MOEOE) group at the 2'-O position and an isobutyryl (iBu) protecting group on the guanine amino group. The 3'-end is functionalized with a cyanoethyl (CE) group, facilitating efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified guanine residues into nucleic acid sequences, enhancing stability and target specificity for applications such as RNA research, gene silencing, and aptamer development.
CAT: BRP-00622
Molecular Formula: C49H64N7O11P
Molecular Weight: 958.06
Purity: ≥95%
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: OATUMETWWCLSRW-LCVXBTAASA-N
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-(2-methoxyethoxy)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C49H64N7O11P/c1-32(2)45(57)53-48-52-44-41(46(58)54-48)51-31-55(44)47-43(63-29-28-62-27-26-59-7)42(67-68(65-25-13-24-50)56(33(3)4)34(5)6)40(66-47)30-64-49(35-14-11-10-12-15-35,36-16-20-38(60-8)21-17-36)37-18-22-39(61-9)23-19-37/h10-12,14-23,31-34,40,42-43,47H,13,25-30H2,1-9H3,(H2,52,53,54,57,58)/t40-,42-,43-,47-,68?/m1/s1
Synonyms: 2'-MOEOE rG(iBu) amidite; N2-iBu-DMT-2'-O-MOEOE-Gr-CE-Phosphoramidite; N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-(2-Methoxyethoxy)ethyl)-guanosine-3'-cyanoethyl Phosphoramidite

DMTr-2'-O-MOEOE-rA(Bz)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOEOE-rA(Bz)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis, featuring a methoxyethoxy (MOEOE) group at the 2'-O position and a benzoyl (Bz) protecting group on the adenine amino group. The 3'-end is functionalized with a cyanoethyl (CE) group, facilitating efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified adenine residues into nucleic acid sequences, enhancing stability and target specificity for various molecular biology applications, including RNA labeling, structural studies, and gene regulation research.
CAT: BRP-00623
Molecular Formula: C52H62N7O10P
Molecular Weight: 976.08
Purity: ≥95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: PKYUXPBRGLVQBQ-MABFDDSHSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCOCCOC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-(2-methoxyethoxy)ethoxy]oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C52H62N7O10P/c1-36(2)59(37(3)4)70(67-28-14-27-53)69-46-44(33-66-52(39-17-12-9-13-18-39,40-19-23-42(62-6)24-20-40)41-21-25-43(63-7)26-22-41)68-51(47(46)65-32-31-64-30-29-61-5)58-35-56-45-48(54-34-55-49(45)58)57-50(60)38-15-10-8-11-16-38/h8-13,15-26,34-37,44,46-47,51H,14,28-33H2,1-7H3,(H,54,55,57,60)/t44-,46-,47-,51-,70?/m1/s1
Synonyms: (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(2-methoxyethoxy)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 2'-MOEOE A(Bz) amidite; N6-Bz-DMT-2'-O-MOEOE-Ar-CE-Phosphoramidite; N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-(2-Methoxyethoxy)ethyl)-adenosine-3'-cyanoethyl Phosphoramidite

DMTr-2'-O-Bu-rA(Bz)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-Bu-rA(Bz)-3'-CE-Phosphoramidite, used in oligonucleotide synthesis, features a butyl (Bu) group at the 2'-O position, and a benzoyl (Bz) protecting group on the adenine amino group. The 3'-end is functionalized with a cyanoethyl (CE) group, facilitating efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified adenine residues into nucleic acid sequences, enhancing stability and target specificity for applications such as RNA labeling, structural studies, and gene regulation research.
CAT: BRP-00624
Molecular Formula: C51H60N7O8P
Molecular Weight: 930.06
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: PGNPDHTYAGNPAM-LTMMGAFGSA-N
CanonicalSMILES: CCCCOC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-butoxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C51H60N7O8P/c1-8-9-30-62-46-45(66-67(64-31-16-29-52)58(35(2)3)36(4)5)43(65-50(46)57-34-55-44-47(53-33-54-48(44)57)56-49(59)37-17-12-10-13-18-37)32-63-51(38-19-14-11-15-20-38,39-21-25-41(60-6)26-22-39)40-23-27-42(61-7)28-24-40/h10-15,17-28,33-36,43,45-46,50H,8-9,16,30-32H2,1-7H3,(H,53,54,56,59)/t43-,45-,46-,50-,67?/m1/s1
Synonyms: (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-butoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

DMTr-2'-O-Et-rA(Bz)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-Et-rA(Bz)-3'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, contains an ethyl (Et) group at the 2'-O position, and a benzoyl (Bz) protecting group on the adenine amino group. The 3'-end is functionalized with a cyanoethyl (CE) group, facilitating efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified adenine residues into nucleic acid sequences, enhancing stability and target specificity for various molecular biology applications, including RNA labeling, gene synthesis, and RNA interference studies.
CAT: BRP-00625
Molecular Formula: C49H56N7O8P
Molecular Weight: 902.00
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: BWEYMSXPRQAMFY-FVPMUMJWSA-N
CanonicalSMILES: CCOC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-ethoxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C49H56N7O8P/c1-8-60-44-43(64-65(62-29-15-28-50)56(33(2)3)34(4)5)41(63-48(44)55-32-53-42-45(51-31-52-46(42)55)54-47(57)35-16-11-9-12-17-35)30-61-49(36-18-13-10-14-19-36,37-20-24-39(58-6)25-21-37)38-22-26-40(59-7)27-23-38/h9-14,16-27,31-34,41,43-44,48H,8,15,29-30H2,1-7H3,(H,51,52,54,57)/t41-,43-,44-,48-,65?/m1/s1
Synonyms: (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-ethoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

DMTr-2'-O-Bu-5-Me-rC(Bz)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-Bu-5-Me-rC(Bz)-3'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, features a butyl (Bu) group at the 2'-O position, and a benzoyl (Bz) protecting group on the 5-methylcytosine (5-Me-rC) amino group. The 3'-end is functionalized with a cyanoethyl (CE) group, facilitating efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified cytosine residues into nucleic acid sequences, enhancing stability and target specificity for applications such as RNA labeling, probing, and therapeutic development.
CAT: BRP-00626
Molecular Formula: C51H62N5O9P
Molecular Weight: 920.06
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: JRVKTZYKHMIWMA-BZPNBFHRSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-butoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C51H62N5O9P/c1-9-10-31-61-46-45(65-66(63-32-17-30-52)56(35(2)3)36(4)5)44(64-49(46)55-33-37(6)47(54-50(55)58)53-48(57)38-18-13-11-14-19-38)34-62-51(39-20-15-12-16-21-39,40-22-26-42(59-7)27-23-40)41-24-28-43(60-8)29-25-41/h11-16,18-29,33,35-36,44-46,49H,9-10,17,31-32,34H2,1-8H3,(H,53,54,57,58)/t44-,45-,46-,49-,66?/m1/s1

DMTr-2'-O-Et-5-Me-rC(Bz)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-Et-5-Me-rC(Bz)-3'-CE-Phosphoramidite, utilized in oligonucleotide synthesis, features an ethyl (Et) group at the 2'-O position, and a benzoyl (Bz) protecting group on the 5-methylcytosine (5-Me-rC) amino group. The 3'-end is functionalized with a cyanoethyl (CE) group, facilitating efficient coupling reactions during solid-phase synthesis. It is employed to introduce modified cytosine residues into nucleic acid sequences, enhancing stability and target specificity for various research applications, including RNA labeling, probing, and therapeutic development.
CAT: BRP-00627
Molecular Formula: C49H58N5O9P
Molecular Weight: 892.00
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: NKWGOVVNANYUQH-ADJAFLDTSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-ethoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C49H58N5O9P/c1-9-59-44-43(63-64(61-30-16-29-50)54(33(2)3)34(4)5)42(62-47(44)53-31-35(6)45(52-48(53)56)51-46(55)36-17-12-10-13-18-36)32-60-49(37-19-14-11-15-20-37,38-21-25-40(57-7)26-22-38)39-23-27-41(58-8)28-24-39/h10-15,17-28,31,33-34,42-44,47H,9,16,30,32H2,1-8H3,(H,51,52,55,56)/t42-,43-,44-,47-,64?/m1/s1
* Only for research. Not suitable for any diagnostic or therapeutic use.

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