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Phosphoramidites

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2'-Modified Phosphoramidites
(529/529) 2'-Phosphoramidites
(27/27) 3'-Modified Phosphoramidites
(201/201) 5'-Modified Phosphoramidites
(30/30) Arabino Phosphoramidites
(23/23) Base Protected Phosphoramidites (418/418) Dye Phosphoramidites
(53/53) Label Phosphoramidites
(80/80) Linker Phosphoramidites
(85/85) Other Phosphoramidites
(97/97) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(25/25) Spacer Phosphoramidites
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2'-MOE C(pac) amidite

Description: 2'-MOE C(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues with 2'-methoxyethyl (2'-MOE) modification and phenoxyacetyl (pac) protection into the oligonucleotide sequence. This compound is essential for synthesizing modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00861
Molecular Formula: C50H60N5O11P
Molecular Weight: 938.03
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: UZRZIHOXKZDIFQ-KUTAVOKMSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)-5-(2-oxo-4-(2-phenoxyacetamido)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C50H60N5O11P/c1-35(2)55(36(3)4)67(64-30-14-28-51)66-46-43(33-63-50(37-15-10-8-11-16-37,38-19-23-40(59-6)24-20-38)39-21-25-41(60-7)26-22-39)65-48(47(46)61-32-31-58-5)54-29-27-44(53-49(54)57)52-45(56)34-62-42-17-12-9-13-18-42/h8-13,15-27,29,35-36,43,46-48H,14,30-34H2,1-7H3,(H,52,53,56,57)/t43-,46-,47-,48-,67?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-C(pac) 3'-CE Phosphoramidite

2'-MOE MeC(dmf) amidite

Description: 2'-MOE MeC(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of 2'-methoxyethyl (2'-MOE) modified cytidine residues with dimethylformamidine (dmf) protection into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00862
Molecular Formula: C46H61N6O9P
Molecular Weight: 873.00
Purity: >97%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: WUCVRRYJZTWUBS-XUMVYBCMSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-(((dimethylamino)methylene)amino)-5-methyl-2-oxopyrimidin-1(2H)-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C46H61N6O9P/c1-32(2)52(33(3)4)62(59-26-14-25-47)61-41-40(60-44(42(41)57-28-27-54-8)51-29-34(5)43(49-45(51)53)48-31-50(6)7)30-58-46(35-15-12-11-13-16-35,36-17-21-38(55-9)22-18-36)37-19-23-39(56-10)24-20-37/h11-13,15-24,29,31-33,40-42,44H,14,26-28,30H2,1-10H3/t40-,41-,42-,44-,62?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-MeC(dmf) 3'-CE Phosphoramidite

2'-MOE A(dmf) amidite

Description: 2'-MOE A(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 2'-methoxyethyl (2'-MOE) modified adenine residues with dimethylformamidine (dmf) protection into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00863
Molecular Formula: C46H59N8O8P
Molecular Weight: 883.00
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: HNUYQNDVGXBRKT-GIDUWHSKSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-(((dimethylamino)methylene)amino)-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C46H59N8O8P/c1-32(2)54(33(3)4)63(60-25-13-24-47)62-41-39(61-45(42(41)58-27-26-55-7)53-31-50-40-43(51-30-52(5)6)48-29-49-44(40)53)28-59-46(34-14-11-10-12-15-34,35-16-20-37(56-8)21-17-35)36-18-22-38(57-9)23-19-36/h10-12,14-23,29-33,39,41-42,45H,13,25-28H2,1-9H3/t39-,41-,42-,45-,63?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-A(dmf) 3'-CE Phosphoramidite

2'-MOE A(pac) amidite

Description: 2'-MOE A(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of adenine residues modified with 2'-methoxyethyl (2'-MOE) and protected with phenoxyacetyl (pac) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00864
Molecular Formula: C51H60N7O10P
Molecular Weight: 962.05
Purity: >97%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: DGWJRMSFFQNJSR-UMSFVQQVSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C51H60N7O10P/c1-35(2)58(36(3)4)69(66-28-14-27-52)68-46-43(31-65-51(37-15-10-8-11-16-37,38-19-23-40(61-6)24-20-38)39-21-25-41(62-7)26-22-39)67-50(47(46)63-30-29-60-5)57-34-55-45-48(53-33-54-49(45)57)56-44(59)32-64-42-17-12-9-13-18-42/h8-13,15-26,33-36,43,46-47,50H,14,28-32H2,1-7H3,(H,53,54,56,59)/t43-,46-,47-,50-,69?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-A(pac) 3'-CE Phosphoramidite

2'-MOE MeC(pac) amidite

Description: 2'-MOE MeC(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues modified with 2'-methoxyethyl (2'-MOE) and protected with phenoxyacetyl (pac) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics,
CAT: BRP-00865
Molecular Formula: C51H62N5O11P
Molecular Weight: 952.06
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: KQFFNZKJAGTJRO-VVFLMUEQSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)-5-(5-methyl-2-oxo-4-(2-phenoxyacetamido)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C51H62N5O11P/c1-35(2)56(36(3)4)68(65-29-15-28-52)67-46-44(33-64-51(38-16-11-9-12-17-38,39-20-24-41(60-7)25-21-39)40-22-26-42(61-8)27-23-40)66-49(47(46)62-31-30-59-6)55-32-37(5)48(54-50(55)58)53-45(57)34-63-43-18-13-10-14-19-43/h9-14,16-27,32,35-36,44,46-47,49H,15,29-31,33-34H2,1-8H3,(H,53,54,57,58)/t44-,46-,47-,49-,68?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-MeC(pac) 3'-CE Phosphoramidite

2'-MOE G(iPr-pac) amidite

Description: 2'-MOE G(iPr-pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of guanine residues modified with 2'-methoxyethyl (2'-MOE) and protected with isopropylphenoxyacetyl (iPr-pac) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00866
Molecular Formula: C54H66N7O11P
Molecular Weight: 1020.13
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: HCOJSGDKIGGZGC-LZDPKHDJSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-(2-(4-isopropylphenoxy)acetamido)-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C54H66N7O11P/c1-35(2)38-16-22-44(23-17-38)68-33-46(62)57-53-58-50-47(51(63)59-53)56-34-60(50)52-49(67-31-30-64-7)48(72-73(70-29-13-28-55)61(36(3)4)37(5)6)45(71-52)32-69-54(39-14-11-10-12-15-39,40-18-24-42(65-8)25-19-40)41-20-26-43(66-9)27-21-41/h10-12,14-27,34-37,45,48-49,52H,13,29-33H2,1-9H3,(H2,57,58,59,62,63)/t45-,48-,49-,52-,73?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-G(iPr-pac) 3'-CE Phosphoramidite

2'-O-NMA A(Bz) amidite

Description: 2'-O-NMA A(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of adenine residues modified with 2'-O-(2-(methylamino)-2-oxoethyl) (NMA) and protected with benzoyl (Bz) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00867
CAS: 1025783-20-3
Molecular Formula: C50H57N8O9P
Molecular Weight: 945.03
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: GEYNOJIHDLPUEX-GNUXOQNYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCC(=O)NC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-(methylamino)-2-oxoethoxy]oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C50H57N8O9P/c1-33(2)58(34(3)4)68(65-28-14-27-51)67-44-41(29-64-50(36-17-12-9-13-18-36,37-19-23-39(61-6)24-20-37)38-21-25-40(62-7)26-22-38)66-49(45(44)63-30-42(59)52-5)57-32-55-43-46(53-31-54-47(43)57)56-48(60)35-15-10-8-11-16-35/h8-13,15-26,31-34,41,44-45,49H,14,28-30H2,1-7H3,(H,52,59)(H,53,54,56,60)/t41-,44-,45-,49-,68?/m1/s1
Synonyms: Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[2-(methylamino)-2-oxoethyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(methylamino)-2-oxoethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-DMT-2'-O-NMA-A(Bz)-3'-CE-Phosphoramidite; [6-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]adenosine]-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite

2'-O-NMA G(iBu) amidite

Description: 2'-O-NMA G(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of guanine residues modified with 2'-O-(2-(methylamino)-2-oxoethyl) (NMA) and protected with isobutyl (iBu) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00868
CAS: 1025783-22-5
Molecular Formula: C47H59N8O10P
Molecular Weight: 927.01
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: BNLNDNDXCOPBTF-NCJSJSGWSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCC(=O)NC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-(methylamino)-2-oxoethoxy]oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C47H59N8O10P/c1-29(2)43(57)52-46-51-42-39(44(58)53-46)50-28-54(42)45-41(61-27-38(56)49-7)40(65-66(63-25-13-24-48)55(30(3)4)31(5)6)37(64-45)26-62-47(32-14-11-10-12-15-32,33-16-20-35(59-8)21-17-33)34-18-22-36(60-9)23-19-34/h10-12,14-23,28-31,37,40-41,45H,13,25-27H2,1-9H3,(H,49,56)(H2,51,52,53,57,58)/t37-,40-,41-,45-,66?/m1/s1
Synonyms: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[2-(methylamino)-2-oxoethyl]-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-(methylamino)-2-oxoethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-DMT-2'-O-NMA-G(iBu)-3'-CE-Phosphoramidite; [5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-2-N-isobutyrylguanosine]-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite

2'-O-NMA MeC(Bz) amidite

Description: 2'-O-NMA MeC(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues modified with 2'-O-(2-(methylamino)-2-oxoethyl) (NMA) and protected with benzoyl (Bz) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00869
CAS: 1025783-18-9
Molecular Formula: C50H59N6O10P
Molecular Weight: 935.03
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: OABRWFIIVWCDDM-WBHVIXSUSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=C(C(=NC2=O)NC(=O)C=3C=CC=CC3)C)C1OCC(=O)NC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(methylamino)-2-oxoethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C50H59N6O10P/c1-33(2)56(34(3)4)67(64-29-15-28-51)66-44-42(31-63-50(37-18-13-10-14-19-37,38-20-24-40(60-7)25-21-38)39-22-26-41(61-8)27-23-39)65-48(45(44)62-32-43(57)52-6)55-30-35(5)46(54-49(55)59)53-47(58)36-16-11-9-12-17-36/h9-14,16-27,30,33-34,42,44-45,48H,15,29,31-32H2,1-8H3,(H,52,57)(H,53,54,58,59)/t42-,44-,45-,48-,67?/m1/s1
Synonyms: Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-methyl-2'-O-[2-(methylamino)-2-oxoethyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-DMT-2'-O-NMA-5-Me-C(Bz)-3'-CE-Phosphoramidite

2'-OAlly A(Bz) amidite

Description: 2'-OAlly A(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of adenine residues modified with 2'-O-allyl and protected with benzoyl (Bz) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00870
CAS: 136834-09-8
Molecular Formula: C50H56N7O8P
Molecular Weight: 914.01
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: PZHYXONYDRPFHJ-XOMUZYEBSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCC=C)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-prop-2-enoxyoxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C50H56N7O8P/c1-8-29-61-45-44(65-66(63-30-15-28-51)57(34(2)3)35(4)5)42(64-49(45)56-33-54-43-46(52-32-53-47(43)56)55-48(58)36-16-11-9-12-17-36)31-62-50(37-18-13-10-14-19-37,38-20-24-40(59-6)25-21-38)39-22-26-41(60-7)27-23-39/h8-14,16-27,32-35,42,44-45,49H,1,15,29-31H2,2-7H3,(H,52,53,55,58)/t42-,44-,45-,49-,66?/m1/s1
Synonyms: (2R,3R,4R,5R)-4-(Allyloxy)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propenyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

2'-OAlly G(iBu) amidite

Description: 2'-OAlly G(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of guanine residues modified with 2'-O-allyl and protected with isobutyl (iBu) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00871
CAS: 163070-99-3
Molecular Formula: C47H58N7O9P
Molecular Weight: 896.00
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: WZIZCXQOBBGIEA-VCGWOZLGSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1OCC=C)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-4-(allyloxy)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C47H58N7O9P/c1-10-26-59-41-40(63-64(61-27-14-25-48)54(31(4)5)32(6)7)38(62-45(41)53-29-49-39-42(53)50-46(52-44(39)56)51-43(55)30(2)3)28-60-47(33-15-12-11-13-16-33,34-17-21-36(57-8)22-18-34)35-19-23-37(58-9)24-20-35/h10-13,15-24,29-32,38,40-41,45H,1,14,26-28H2,2-9H3,(H2,50,51,52,55,56)/t38-,40-,41-,45-,64?/m1/s1
Synonyms: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-2-propenyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

2'-OAlly U amidite

Description: 2'-OAlly U amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of uracil residues modified with 2'-O-allyl into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00872
CAS: 171486-64-9
Molecular Formula: C42H51N4O9P
Molecular Weight: 786.86
Purity: >95%
Appearance: Off-white solid
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InChIKey: PRCRTSIDLZWSDO-CYSIDSPMSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCC=C)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
IUPAC Name: 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-prop-2-enoxyoxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C42H51N4O9P/c1-8-26-51-39-38(55-56(53-27-12-24-43)46(29(2)3)30(4)5)36(54-40(39)45-25-23-37(47)44-41(45)48)28-52-42(31-13-10-9-11-14-31,32-15-19-34(49-6)20-16-32)33-17-21-35(50-7)22-18-33/h8-11,13-23,25,29-30,36,38-40H,1,12,26-28H2,2-7H3,(H,44,47,48)/t36-,38-,39-,40-,56?/m1/s1
Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-2-propenyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-4-(allyloxy)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5-O-(4,4'-dimethoxytrityl)-2-O-allyl-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1-deoxy-1-uracil-1-yl-beta-D-ribo-pentofuranose

2'-OTBS MeC(pac) amidite

Description: 2'-OTBS MeC(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues modified with 2'-O-tert-butyldimethylsilyl (2'-OTBS) and protected with phenoxyacetyl (pac) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00873
Molecular Formula: C54H70N5O10PSi
Molecular Weight: 1008.24
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: HKKHIMPFWSYKJT-XCUKYXTNSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(5-methyl-2-oxo-4-(2-phenoxyacetamido)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C54H70N5O10PSi/c1-37(2)59(38(3)4)70(66-33-19-32-55)68-48-46(35-65-54(40-20-15-13-16-21-40,41-24-28-43(62-9)29-25-41)42-26-30-44(63-10)31-27-42)67-51(49(48)69-71(11,12)53(6,7)8)58-34-39(5)50(57-52(58)61)56-47(60)36-64-45-22-17-14-18-23-45/h13-18,20-31,34,37-38,46,48-49,51H,19,33,35-36H2,1-12H3,(H,56,57,60,61)/t46-,48-,49-,51-,70?/m1/s1
Synonyms: 5'-O-DMT-2'-O-TBDMS-5-Me-C(pac) 3'-CE Phosphoramidite

2'-OPivOM U amidite

Description: 2'-O-PivOM U amidite is a specialized nucleotide for oligonucleotide synthesis, featuring a pivaloyloxymethyl (PivOM) group protecting the 2'-hydroxyl group of uridine. This modification enhances stability during synthesis and can be removed under mild acidic conditions post-synthesis. The amidite functionality allows for the stepwise addition of this nucleotide in solid-phase synthesis, making it essential for creating RNA molecules with specific modifications for research and therapeutic applications.
CAT: BRP-00874
CAS: 1097131-15-1
Molecular Formula: C45H57N4O11P
Molecular Weight: 860.94
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: CWFIVBQKXNPXJJ-WXSPLRIASA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCOC(=O)C(C)(C)C)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
IUPAC Name: [(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxymethyl 2,2-dimethylpropanoate
InChI: InChI=1S/C45H57N4O11P/c1-30(2)49(31(3)4)61(58-27-13-25-46)60-39-37(59-41(48-26-24-38(50)47-43(48)52)40(39)55-29-56-42(51)44(5,6)7)28-57-45(32-14-11-10-12-15-32,33-16-20-35(53-8)21-17-33)34-18-22-36(54-9)23-19-34/h10-12,14-24,26,30-31,37,39-41H,13,27-29H2,1-9H3,(H,47,50,52)/t37-,39-,40-,41-,61?/m1/s1
Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(2,2-dimethyl-1-oxopropoxy)methyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)oxy)methyl pivalate; 2'-O-PivOM-5'-O-DMT-Uridine 3'-CEP

2'-OPivOM C(Ac) amidite

Description: 2'-O-PivOM C(Ac) amidite is a modified cytidine nucleotide used in oligonucleotide synthesis. It features a 2'-O-pivaloyloxymethyl group protecting the 2'-hydroxyl and an acetyl group protecting the amino group at the 4-position, facilitating stepwise addition during solid-phase synthesis. This allows for the creation of RNA molecules with specific modifications.
CAT: BRP-00875
CAS: 1097131-18-4
Molecular Formula: C47H60N5O11P
Molecular Weight: 902.00
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: XGSYTNZPEKBGAM-JFALYFJISA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCOC(=O)C(C)(C)C)N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
IUPAC Name: [(2R,3R,4R,5R)-2-(4-acetamido-2-oxopyrimidin-1-yl)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-3-yl]oxymethyl 2,2-dimethylpropanoate
InChI: InChI=1S/C47H60N5O11P/c1-31(2)52(32(3)4)64(61-28-14-26-48)63-41-39(62-43(42(41)58-30-59-44(54)46(6,7)8)51-27-25-40(49-33(5)53)50-45(51)55)29-60-47(34-15-12-11-13-16-34,35-17-21-37(56-9)22-18-35)36-19-23-38(57-10)24-20-36/h11-13,15-25,27,31-32,39,41-43H,14,28-30H2,1-10H3,(H,49,50,53,55)/t39-,41-,42-,43-,64?/m1/s1
Synonyms: Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(2,2-dimethyl-1-oxopropoxy)methyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (((2R,3R,4R,5R)-2-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-3-yl)oxy)methyl pivalate; 2'-O-PivOM-5'-O-DMT-Cytidine (N-Ac) 3'-CEP

2'-OPivOM A(pac) amidite

Description: 2'-O-PivOM A(Pac) amidite is a modified adenosine nucleotide used in oligonucleotide synthesis. It includes a 2'-O-pivaloyloxymethyl group protecting the 2'-hydroxyl and a phenoxyacetyl (Pac) group protecting the exocyclic amino group at the N6 position, enabling precise incorporation during solid-phase synthesis for constructing RNA sequences with desired modifications.
CAT: BRP-00876
CAS: 1097131-21-9
Molecular Formula: C54H64N7O11P
Molecular Weight: 1018.12
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: JMGAJBBCWCMKLV-PQTVSCHKSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCOC(=O)C(C)(C)C)N2C=NC3=C(N=CN=C32)NC(=O)COC4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
IUPAC Name: [(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2-[6-[(2-phenoxyacetyl)amino]purin-9-yl]oxolan-3-yl]oxymethyl 2,2-dimethylpropanoate
InChI: InChI=1S/C54H64N7O11P/c1-36(2)61(37(3)4)73(70-30-16-29-55)72-47-44(31-69-54(38-17-12-10-13-18-38,39-21-25-41(64-8)26-22-39)40-23-27-42(65-9)28-24-40)71-51(48(47)67-35-68-52(63)53(5,6)7)60-34-58-46-49(56-33-57-50(46)60)59-45(62)32-66-43-19-14-11-15-20-43/h10-15,17-28,33-34,36-37,44,47-48,51H,16,30-32,35H2,1-9H3,(H,56,57,59,62)/t44-,47-,48-,51-,73?/m1/s1
Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(2,2-dimethyl-1-oxopropoxy)methyl]-N-(2-phenoxyacetyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-2-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl)oxy)methyl pivalate; 2'-O-PivOM-5'-O-DMT-Adenosine (N-PAC) 3'-CEP

2'-OTBS A(Ac) amidite

Description: 2'-OTBS A(Ac) amidite is a specialized compound used in oligonucleotide synthesis. It contains a nucleoside derivative with a tert-butyldimethylsilyl (OTBS) group protecting the 2'-hydroxyl position of adenosine. Additionally, it features an acetyl (Ac) group attached to the amine group of the adenosine base. This compound enables controlled addition during oligonucleotide synthesis, allowing for precise customization and design of adenosine-modified oligonucleotides for various molecular biology applications, such as RNA interference (RNAi) studies and gene expression analysis.
CAT: BRP-00877
CAS: 1220889-84-8
Molecular Formula: C48H64N7O8PSi
Molecular Weight: 926.14
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: IISGHHSYMWMWKH-FLEVKJGDSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=NC3=C(N=CN=C32)NC(=O)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]acetamide
InChI: InChI=1S/C48H64N7O8PSi/c1-32(2)55(33(3)4)64(60-28-16-27-49)62-42-40(61-46(43(42)63-65(11,12)47(6,7)8)54-31-52-41-44(53-34(5)56)50-30-51-45(41)54)29-59-48(35-17-14-13-15-18-35,36-19-23-38(57-9)24-20-36)37-21-25-39(58-10)26-22-37/h13-15,17-26,30-33,40,42-43,46H,16,28-29H2,1-12H3,(H,50,51,53,56)/t40-,42-,43-,46-,64?/m1/s1
Synonyms: Adenosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(trimethylsilyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; DMT-2'-O-TBDMS-A(Ac)-CE Phosphoramidite; 2'-O-TBDMS-A(Ac) CE Phosphoramidite; (2R,3R,4R,5R)-5-(6-Acetamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 2'-tBDSilyl Adenosine (n-acetyl) CED phosphoramidite

2'-OTBS O6-NPE-I amidite

Description: 2'-OTBS O6-NPE-I amidite is a chemically modified phosphoramidite used in the synthesis of oligonucleotides. This compound features inosine as the nucleoside base, with an O6 position protected by a nitrophenylethyl (NPE) group. Additionally, the ribose sugar is protected at the 2' position with a tert-butyldimethylsilyl (TBS) group. This phosphoramidite is specifically designed for incorporation into DNA or RNA sequences during solid-phase oligonucleotide synthesis. The TBS and NPE protecting groups ensure selective deprotection, allowing for precise modifications of oligonucleotides. This modified amidite is useful in various research applications, including the study of nucleotide interactions, enzymatic processing of modified nucleotides, and the development of therapeutic oligonucleotides, particularly those requiring enhanced stability or specific chemical modifications.
CAT: BRP-00878
CAS: 151059-66-4
Molecular Formula: C54H68N7O10PSi
Molecular Weight: 1034.24
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: ORFDMMXBXUZNMM-YYONJIEZSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(6-(4-nitrophenethoxy)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C54H68N7O10PSi/c1-37(2)60(38(3)4)72(68-32-15-31-55)70-48-46(34-67-54(40-16-13-12-14-17-40,41-20-26-44(64-8)27-21-41)42-22-28-45(65-9)29-23-42)69-52(49(48)71-73(10,11)53(5,6)7)59-36-58-47-50(59)56-35-57-51(47)66-33-30-39-18-24-43(25-19-39)61(62)63/h12-14,16-29,35-38,46,48-49,52H,15,30,32-34H2,1-11H3/t46-,48-,49-,52-,72?/m1/s1
Synonyms: 5'-O-DMT-2'-O-TBDMS O6-NPE-I 3'-CE Phosphoramidite

2'-OTBS C(pac) amidite

Description: 2'-OTBS C(Pac) amidite is a specialized compound used in oligonucleotide synthesis. It consists of a nucleoside derivative with a tert-butyldimethylsilyl (OTBS) group protecting the 2'-hydroxyl position of cytidine. Additionally, it features a phenoxyacetyl (Pac) group attached to the amine group of the cytidine base. This compound facilitates controlled addition during oligonucleotide synthesis, enabling precise customization and design of cytidine-modified oligonucleotides for various molecular biology applications, including RNA interference (RNAi) studies, gene expression analysis, and antisense oligonucleotide design.
CAT: BRP-00879
CAS: 259144-69-9
Molecular Formula: C53H68N5O10PSi
Molecular Weight: 994.21
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: HUTVBXXKUWIFOM-OPZOZVPWSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(2-oxo-4-(2-phenoxyacetamido)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C53H68N5O10PSi/c1-37(2)58(38(3)4)69(65-34-18-32-54)67-48-45(35-64-53(39-19-14-12-15-20-39,40-23-27-42(61-8)28-24-40)41-25-29-43(62-9)30-26-41)66-50(49(48)68-70(10,11)52(5,6)7)57-33-31-46(56-51(57)60)55-47(59)36-63-44-21-16-13-17-22-44/h12-17,19-31,33,37-38,45,48-50H,18,34-36H2,1-11H3,(H,55,56,59,60)/t45-,48-,49-,50-,69?/m1/s1
Synonyms: 2'-tBDSilyl Cytidine (n-PAC) CED phosphoramidite; 2'-O-TBDMS C(pac) 3'-CE phosphoramidite

2'-OMe O6-NPE-I amidite

Description: 2'-OTBS O6-NPE-I amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of nucleosides modified at the O6 position with NPE (nitrophenylethyl) functionality and protected with tert-butyldimethylsilyl (OTBS) into the oligonucleotide sequence. This compound is important for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00880
Molecular Formula: C49H56N7O10P
Molecular Weight: 934.00
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: WOXYNKAZRDURES-WBHVIXSUSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxy-5-(6-(4-nitrophenethoxy)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C49H56N7O10P/c1-33(2)55(34(3)4)67(64-28-11-27-50)66-44-42(30-63-49(36-12-9-8-10-13-36,37-16-22-40(59-5)23-17-37)38-18-24-41(60-6)25-19-38)65-48(45(44)61-7)54-32-53-43-46(54)51-31-52-47(43)62-29-26-35-14-20-39(21-15-35)56(57)58/h8-10,12-25,31-34,42,44-45,48H,11,26,28-30H2,1-7H3/t42-,44-,45-,48-,67?/m1/s1
Synonyms: 5'-O-DMT-2'-O-Me O6-NPE-I 3'-CE Phosphoramidite
* Only for research. Not suitable for any diagnostic or therapeutic use.

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