Phosphoramidites

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2'-Modified Phosphoramidites
(466/466) 2'-Phosphoramidites
(21/21) 3'-Modified Phosphoramidites
(186/186) 5'-Modified Phosphoramidites
(21/21) Arabino Phosphoramidites
(19/19) Base Protected Phosphoramidites (365/365) Dye Phosphoramidites
(53/53) Label Phosphoramidites
(82/82) Linker Phosphoramidites
(72/72) Other Phosphoramidites
(92/92) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(15/15) Spacer Phosphoramidites
(22/22)
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(S)-BuNA G(iBu) amidite

Description: (S)-BuNA G(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00850
MF: C43H54N7O7P
MF: 811.92
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: JDXNYQOHJJNIOS-BVARLVFGSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2CC(CCOC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxybutyl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C43H54N7O7P/c1-29(2)40(51)47-42-46-39-38(41(52)48-42)45-28-49(39)27-37(57-58(56-25-12-24-44)50(30(3)4)31(5)6)23-26-55-43(32-13-10-9-11-14-32,33-15-19-35(53-7)20-16-33)34-17-21-36(54-8)22-18-34/h9-11,13-22,28-31,37H,12,23,25-27H2,1-8H3,(H2,46,47,48,51,52)/t37-,58?/m0/s1
Synonyms: (S)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-1-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)butan-2-yl (2-cyanoethyl) diisopropylphosphoramidite

3'-O-Me-U-2'-phosphoramidite

Description: 3'-O-Me-U-2'-phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 3'-O-methyluridine residues into the oligonucleotide sequence. 3'-O-Me-U-2'-phosphoramidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00851
CAS: 179479-05-1
MF: C40H49N4O9P
MF: 760.83
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: FPRLFGWVAXFXTL-XKZJCBTISA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OC
IUPAC Name: 3-[[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-2-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C40H49N4O9P/c1-27(2)44(28(3)4)54(51-25-11-23-41)53-37-36(49-7)34(52-38(37)43-24-22-35(45)42-39(43)46)26-50-40(29-12-9-8-10-13-29,30-14-18-32(47-5)19-15-30)31-16-20-33(48-6)21-17-31/h8-10,12-22,24,27-28,34,36-38H,11,25-26H2,1-7H3,(H,42,45,46)/t34-,36-,37-,38-,54?/m1/s1
Synonyms: 3'-OMe U 2'-amidite; 5'-O-(4,4'-Dimethoxytrityl)-3'-O-methyl-uridine-2'-cyanoethyl phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-DMTr-3'-O-methyluridine-2'-CED-phosphoramidite; 3'-OMe-U Phosphoramidite; 5'-O-DMTr-3'-O-methyluridine-3'-CED-phosphoramidite; 3'-O-Methyl Uridine CED phosphoramidite

3'-O-Me-C(Ac)-2'-phosphoramidite

Description: 3'-O-Me-C(Ac)-2'-phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 3'-O-methylcytidine residues with acetyl protection into the oligonucleotide sequence. 3'-O-Me-C(Ac)-2'-phosphoramidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00852
MF: C42H52N5O9P
MF: 801.88
Purity: >95%
Appearance: Off-white solid
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InChIKey: GATGWWGSSVDAEU-UAQIPLLRSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OC
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C42H52N5O9P/c1-28(2)47(29(3)4)57(54-26-12-24-43)56-39-38(52-8)36(55-40(39)46-25-23-37(44-30(5)48)45-41(46)49)27-53-42(31-13-10-9-11-14-31,32-15-19-34(50-6)20-16-32)33-17-21-35(51-7)22-18-33/h9-11,13-23,25,28-29,36,38-40H,12,26-27H2,1-8H3,(H,44,45,48,49)/t36-,38-,39-,40-,57?/m1/s1
Synonyms: (2R,3R,4R,5R)-2-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 3'-OMe C(Ac) 2'-amidite; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methyl-cytidine-2'-cyanoethyl phosphoramidite; 3'-OMe-C(Ac) Phosphoramidite

3'-O-Me-C(Bz)-2'-phosphoramidite

Description: 3'-O-Me-C(Bz)-2'-phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 3'-O-methylcytidine residues with benzoyl protection into the oligonucleotide sequence. 3'-O-Me-C(Bz)-2'-phosphoramidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00853
CAS: 179479-03-9
MF: C47H54N5O9P
MF: 863.95
Purity: >95%
Appearance: Off-white solid
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InChIKey: BENGZEFYMXNUAR-VKBHKTMGSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OC
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C47H54N5O9P/c1-32(2)52(33(3)4)62(59-30-14-28-48)61-43-42(57-7)40(60-45(43)51-29-27-41(50-46(51)54)49-44(53)34-15-10-8-11-16-34)31-58-47(35-17-12-9-13-18-35,36-19-23-38(55-5)24-20-36)37-21-25-39(56-6)26-22-37/h8-13,15-27,29,32-33,40,42-43,45H,14,30-31H2,1-7H3,(H,49,50,53,54)/t40-,42-,43-,45-,62?/m1/s1
Synonyms: 3'-OMe C(Bz) 2'-amidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N4-Bz-5'-O-DMTr-3'-O-methylcytidine-2'-CED-phosphoramidite; 3'-O-Methyl Cytidine (n-bz) CED phosphoramidite

3'-O-Me-G(iBu)-2'-phosphoramidite

Description: 3'-O-Me-G(iBu)-2'-phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 3'-O-methylguanosine residues with isobutyl protection into the oligonucleotide sequence. 3'-O-Me-G(iBu)-2'-phosphoramidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00854
CAS: 179479-04-0
MF: C45H56N7O9P
MF: 869.96
Purity: >95%
Appearance: Off-white solid
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InChIKey: POYXHFZLQWXZTI-MLLDKZSOSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(61-62(59-25-13-24-46)52(29(3)4)30(5)6)38(57-9)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/m1/s1
Synonyms: 3'-OMe G(iBu) 2'-amidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-DMTr-N2-iso-butyroyl-3'-O-methylguanosine-2'-CED-phosphoramidite; 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)guanosine, 2'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylguanosine-2'-cyanoethyl phosphoramidite; 3'-O-Methyl Guanosine (n-ibu) CED phosphoramidite

2'-TFA-AE A(iBu) amidite

Description: 2'-TFA-AE A(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of adenine residues with 2'-trifluoroacetyl modification and isobutyl protection into the oligonucleotide sequence. 2'-TFA-AE A(iBu) amidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00855
CAS: 853748-67-1
MF: C48H58F3N8O9P
MF: 979.01
Purity: >95%
Appearance: Off-white solid
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InChIKey: PDBNCRNDNUXWIB-KUGYPCBWSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCNC(=O)C(F)(F)F
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-[(2,2,2-trifluoroacetyl)amino]ethoxy]oxolan-2-yl]purin-6-yl]-2-methylpropanamide
InChI: InChI=1S/C48H58F3N8O9P/c1-30(2)44(60)57-42-39-43(55-28-54-42)58(29-56-39)45-41(64-26-24-53-46(61)48(49,50)51)40(68-69(66-25-12-23-52)59(31(3)4)32(5)6)38(67-45)27-65-47(33-13-10-9-11-14-33,34-15-19-36(62-7)20-16-34)35-17-21-37(63-8)22-18-35/h9-11,13-22,28-32,38,40-41,45H,12,24-27H2,1-8H3,(H,53,61)(H,54,55,57,60)/t38-,40-,41-,45-,69?/m1/s1
Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-[2-[(trifluoroacetyl)amino]ethyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-isobutyramido-9H-purin-9-yl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-O-(TFA-aminoethyl)-A(iBu) 3'-CE Phosphoramidite

2'-TFA-AE G(iBu) amidite

Description: 2'-TFA-AE G(iBu) amidite is a modified phosphoramidite utilized in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of guanine residues with 2'-trifluoroacetyl modification and isobutyl protection into the oligonucleotide sequence. This compound is valuable for synthesizing modified oligonucleotides for diverse applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00856
CAS: 853748-79-5
MF: C48H58F3N8O10P
MF: 995.01
Purity: >95%
Appearance: Off-white solid
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InChIKey: XIQAQHLVRVPSFM-DYTYPCPCSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCNC(=O)C(F)(F)F
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-[(2,2,2-trifluoroacetyl)amino]ethoxy]oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C48H58F3N8O10P/c1-29(2)42(60)56-46-55-41-38(43(61)57-46)54-28-58(41)44-40(65-26-24-53-45(62)48(49,50)51)39(69-70(67-25-12-23-52)59(30(3)4)31(5)6)37(68-44)27-66-47(32-13-10-9-11-14-32,33-15-19-35(63-7)20-16-33)34-17-21-36(64-8)22-18-34/h9-11,13-22,28-31,37,39-40,44H,12,24-27H2,1-8H3,(H,53,62)(H2,55,56,57,60,61)/t37-,39-,40-,44-,70?/m1/s1
Synonyms: (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-3,6-dihydro-9H-purin-9-yl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-O-(TFA-aminoethyl)-G(iBu) 3'-CE Phosphoramidite

2'-TFA-AE U amidite

Description: 2'-TFA-AE U amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of uracil residues with 2'-trifluoroacetyl modification into the oligonucleotide sequence. This compound is essential for synthesizing modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00857
CAS: 853748-56-8
MF: C43H51F3N5O10P
MF: 885.87
Purity: >95%
Appearance: Off-white solid
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InChIKey: YBHWJTBVGJAGKI-BVGHISPXSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCNC(=O)C(F)(F)F)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
IUPAC Name: N-[2-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxyethyl]-2,2,2-trifluoroacetamide
InChI: InChI=1S/C43H51F3N5O10P/c1-28(2)51(29(3)4)62(59-25-10-22-47)61-37-35(60-39(50-24-21-36(52)49-41(50)54)38(37)57-26-23-48-40(53)43(44,45)46)27-58-42(30-11-8-7-9-12-30,31-13-17-33(55-5)18-14-31)32-15-19-34(56-6)20-16-32/h7-9,11-21,24,28-29,35,37-39H,10,23,25-27H2,1-6H3,(H,48,53)(H,49,52,54)/t35-,37-,38-,39-,62?/m1/s1
Synonyms: 5'-O-DMT-2'-O-(TFA-aminoethyl)-rU 3'-CE Phosphoramidite; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

2'-TFA-AE G(Ac) amidite

Description: 2'-TFA-AE G(Ac) amidite is a modified phosphoramidite employed in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of guanine residues with 2'-trifluoroacetyl modification and acetyl protection into the oligonucleotide sequence. This compound is crucial for synthesizing modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00858
CAS: 911110-89-9
MF: C46H54F3N8O10P
MF: 966.95
Purity: >95%
Appearance: Off-white solid
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InChIKey: MHPBJBUMRBEOBZ-DZAGQWDNSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCNC(=O)C(F)(F)F)N2C=NC3=C2N=C(NC3=O)NC(=O)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC
IUPAC Name: N-[2-[(2R,3R,4R,5R)-2-(2-acetamido-6-oxo-1H-purin-9-yl)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-3-yl]oxyethyl]-2,2,2-trifluoroacetamide
InChI: InChI=1S/C46H54F3N8O10P/c1-28(2)57(29(3)4)68(65-24-11-22-50)67-38-36(26-64-45(31-12-9-8-10-13-31,32-14-18-34(61-6)19-15-32)33-16-20-35(62-7)21-17-33)66-42(39(38)63-25-23-51-43(60)46(47,48)49)56-27-52-37-40(56)54-44(53-30(5)58)55-41(37)59/h8-10,12-21,27-29,36,38-39,42H,11,23-26H2,1-7H3,(H,51,60)(H2,53,54,55,58,59)/t36-,38-,39-,42-,68?/m1/s1
Synonyms: Guanosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[2-[(trifluoroacetyl)amino]ethyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-5-(2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-O-(TFA-aminoethyl)-G(Ac) 3'-CE Phosphoramidite

2'-TFA-AE MeC(Bz) amidite

Description: 2'-TFA-AE MeC(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 5-methylcytidine residues with 2'-trifluoroacetyl modification and benzoyl protection into the oligonucleotide sequence. This compound is essential for synthesizing modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00859
CAS: 911110-81-1
MF: C51H58F3N6O10P
MF: 1003.03
Purity: >95%
Appearance: Off-white solid
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InChIKey: SXKUHFATFPKDLA-DCGXNHRISA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCNC(=O)C(F)(F)F
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-[(2,2,2-trifluoroacetyl)amino]ethoxy]oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C51H58F3N6O10P/c1-33(2)60(34(3)4)71(68-29-14-27-55)70-43-42(32-67-50(37-17-12-9-13-18-37,38-19-23-40(64-6)24-20-38)39-21-25-41(65-7)26-22-39)69-47(44(43)66-30-28-56-48(62)51(52,53)54)59-31-35(5)45(58-49(59)63)57-46(61)36-15-10-8-11-16-36/h8-13,15-26,31,33-34,42-44,47H,14,28-30,32H2,1-7H3,(H,56,62)(H,57,58,61,63)/t42-,43-,44-,47-,71?/m1/s1
Synonyms: 5'-O-DMT-2'-O-(TFA-aminoethyl)-MeC(Bz) 3'-CE Phosphoramidite; (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

2'-(PHT)aminoethyl U amidite

Description: 2'-(PHT)aminoethyl U amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of uracil residues with a 2'-(PHT)aminoethyl modification into the oligonucleotide sequence. This compound is important for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00860
CAS: 1037523-39-9
MF: C49H54N5O11P
MF: 919.97
Purity: >95%
Appearance: Off-white solid
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InChIKey: VIVGUNXKRHKESW-FEVKEASNSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCN2C(=O)C3=CC=CC=C3C2=O)N4C=CC(=O)NC4=O)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
IUPAC Name: 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-(1,3-dioxoisoindol-2-yl)ethoxy]-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C49H54N5O11P/c1-32(2)54(33(3)4)66(63-29-12-26-50)65-43-41(31-62-49(34-13-8-7-9-14-34,35-17-21-37(59-5)22-18-35)36-19-23-38(60-6)24-20-36)64-47(53-27-25-42(55)51-48(53)58)44(43)61-30-28-52-45(56)39-15-10-11-16-40(39)46(52)57/h7-11,13-25,27,32-33,41,43-44,47H,12,28-31H2,1-6H3,(H,51,55,58)/t41-,43-,44-,47-,66?/m1/s1
Synonyms: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-(PHT)aminoethyl-U 3'-CE Phosphoramidite

2'-MOE C(pac) amidite

Description: 2'-MOE C(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues with 2'-methoxyethyl (2'-MOE) modification and phenoxyacetyl (pac) protection into the oligonucleotide sequence. This compound is essential for synthesizing modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00861
MF: C50H60N5O11P
MF: 938.03
Purity: >95%
Appearance: Off-white solid
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InChIKey: UZRZIHOXKZDIFQ-KUTAVOKMSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)-5-(2-oxo-4-(2-phenoxyacetamido)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C50H60N5O11P/c1-35(2)55(36(3)4)67(64-30-14-28-51)66-46-43(33-63-50(37-15-10-8-11-16-37,38-19-23-40(59-6)24-20-38)39-21-25-41(60-7)26-22-39)65-48(47(46)61-32-31-58-5)54-29-27-44(53-49(54)57)52-45(56)34-62-42-17-12-9-13-18-42/h8-13,15-27,29,35-36,43,46-48H,14,30-34H2,1-7H3,(H,52,53,56,57)/t43-,46-,47-,48-,67?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-C(pac) 3'-CE Phosphoramidite

2'-MOE MeC(dmf) amidite

Description: 2'-MOE MeC(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of 2'-methoxyethyl (2'-MOE) modified cytidine residues with dimethylformamidine (dmf) protection into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00862
MF: C46H61N6O9P
MF: 873.00
Purity: >97%
Appearance: Off-white solid
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InChIKey: WUCVRRYJZTWUBS-XUMVYBCMSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-(((dimethylamino)methylene)amino)-5-methyl-2-oxopyrimidin-1(2H)-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C46H61N6O9P/c1-32(2)52(33(3)4)62(59-26-14-25-47)61-41-40(60-44(42(41)57-28-27-54-8)51-29-34(5)43(49-45(51)53)48-31-50(6)7)30-58-46(35-15-12-11-13-16-35,36-17-21-38(55-9)22-18-36)37-19-23-39(56-10)24-20-37/h11-13,15-24,29,31-33,40-42,44H,14,26-28,30H2,1-10H3/t40-,41-,42-,44-,62?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-MeC(dmf) 3'-CE Phosphoramidite

2'-MOE A(dmf) amidite

Description: 2'-MOE A(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 2'-methoxyethyl (2'-MOE) modified adenine residues with dimethylformamidine (dmf) protection into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00863
MF: C46H59N8O8P
MF: 883.00
Purity: >98%
Appearance: Off-white solid
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InChIKey: HNUYQNDVGXBRKT-GIDUWHSKSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-(((dimethylamino)methylene)amino)-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C46H59N8O8P/c1-32(2)54(33(3)4)63(60-25-13-24-47)62-41-39(61-45(42(41)58-27-26-55-7)53-31-50-40-43(51-30-52(5)6)48-29-49-44(40)53)28-59-46(34-14-11-10-12-15-34,35-16-20-37(56-8)21-17-35)36-18-22-38(57-9)23-19-36/h10-12,14-23,29-33,39,41-42,45H,13,25-28H2,1-9H3/t39-,41-,42-,45-,63?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-A(dmf) 3'-CE Phosphoramidite

2'-MOE A(pac) amidite

Description: 2'-MOE A(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of adenine residues modified with 2'-methoxyethyl (2'-MOE) and protected with phenoxyacetyl (pac) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00864
MF: C51H60N7O10P
MF: 962.05
Purity: >97%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: DGWJRMSFFQNJSR-UMSFVQQVSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C51H60N7O10P/c1-35(2)58(36(3)4)69(66-28-14-27-52)68-46-43(31-65-51(37-15-10-8-11-16-37,38-19-23-40(61-6)24-20-38)39-21-25-41(62-7)26-22-39)67-50(47(46)63-30-29-60-5)57-34-55-45-48(53-33-54-49(45)57)56-44(59)32-64-42-17-12-9-13-18-42/h8-13,15-26,33-36,43,46-47,50H,14,28-32H2,1-7H3,(H,53,54,56,59)/t43-,46-,47-,50-,69?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-A(pac) 3'-CE Phosphoramidite

2'-MOE MeC(pac) amidite

Description: 2'-MOE MeC(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues modified with 2'-methoxyethyl (2'-MOE) and protected with phenoxyacetyl (pac) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics,
CAT: BRP-00865
MF: C51H62N5O11P
MF: 952.06
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: KQFFNZKJAGTJRO-VVFLMUEQSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)-5-(5-methyl-2-oxo-4-(2-phenoxyacetamido)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C51H62N5O11P/c1-35(2)56(36(3)4)68(65-29-15-28-52)67-46-44(33-64-51(38-16-11-9-12-17-38,39-20-24-41(60-7)25-21-39)40-22-26-42(61-8)27-23-40)66-49(47(46)62-31-30-59-6)55-32-37(5)48(54-50(55)58)53-45(57)34-63-43-18-13-10-14-19-43/h9-14,16-27,32,35-36,44,46-47,49H,15,29-31,33-34H2,1-8H3,(H,53,54,57,58)/t44-,46-,47-,49-,68?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-MeC(pac) 3'-CE Phosphoramidite

2'-MOE G(iPr-pac) amidite

Description: 2'-MOE G(iPr-pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of guanine residues modified with 2'-methoxyethyl (2'-MOE) and protected with isopropylphenoxyacetyl (iPr-pac) into the oligonucleotide sequence. This compound is crucial for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00866
MF: C54H66N7O11P
MF: 1020.13
Purity: >95%
Appearance: Off-white solid
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InChIKey: HCOJSGDKIGGZGC-LZDPKHDJSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-(2-(4-isopropylphenoxy)acetamido)-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C54H66N7O11P/c1-35(2)38-16-22-44(23-17-38)68-33-46(62)57-53-58-50-47(51(63)59-53)56-34-60(50)52-49(67-31-30-64-7)48(72-73(70-29-13-28-55)61(36(3)4)37(5)6)45(71-52)32-69-54(39-14-11-10-12-15-39,40-18-24-42(65-8)25-19-40)41-20-26-43(66-9)27-21-41/h10-12,14-27,34-37,45,48-49,52H,13,29-33H2,1-9H3,(H2,57,58,59,62,63)/t45-,48-,49-,52-,73?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-G(iPr-pac) 3'-CE Phosphoramidite

2'-O-NMA A(Bz) amidite

Description: 2'-O-NMA A(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of adenine residues modified with 2'-O-(2-(methylamino)-2-oxoethyl) (NMA) and protected with benzoyl (Bz) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00867
CAS: 1025783-20-3
MF: C50H57N8O9P
MF: 945.03
Purity: >98%
Appearance: Off-white solid
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InChIKey: GEYNOJIHDLPUEX-GNUXOQNYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCC(=O)NC)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-(methylamino)-2-oxoethoxy]oxolan-2-yl]purin-6-yl]benzamide
InChI: InChI=1S/C50H57N8O9P/c1-33(2)58(34(3)4)68(65-28-14-27-51)67-44-41(29-64-50(36-17-12-9-13-18-36,37-19-23-39(61-6)24-20-37)38-21-25-40(62-7)26-22-38)66-49(45(44)63-30-42(59)52-5)57-32-55-43-46(53-31-54-47(43)57)56-48(60)35-15-10-8-11-16-35/h8-13,15-26,31-34,41,44-45,49H,14,28-30H2,1-7H3,(H,52,59)(H,53,54,56,60)/t41-,44-,45-,49-,68?/m1/s1
Synonyms: Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[2-(methylamino)-2-oxoethyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(methylamino)-2-oxoethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-DMT-2'-O-NMA-A(Bz)-3'-CE-Phosphoramidite; [6-N-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]adenosine]-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite

2'-O-NMA G(iBu) amidite

Description: 2'-O-NMA G(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of guanine residues modified with 2'-O-(2-(methylamino)-2-oxoethyl) (NMA) and protected with isobutyl (iBu) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00868
CAS: 1025783-22-5
MF: C47H59N8O10P
MF: 927.01
Purity: >98%
Appearance: Off-white solid
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InChIKey: BNLNDNDXCOPBTF-NCJSJSGWSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCC(=O)NC
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-(methylamino)-2-oxoethoxy]oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C47H59N8O10P/c1-29(2)43(57)52-46-51-42-39(44(58)53-46)50-28-54(42)45-41(61-27-38(56)49-7)40(65-66(63-25-13-24-48)55(30(3)4)31(5)6)37(64-45)26-62-47(32-14-11-10-12-15-32,33-16-20-35(59-8)21-17-33)34-18-22-36(60-9)23-19-34/h10-12,14-23,28-31,37,40-41,45H,13,25-27H2,1-9H3,(H,49,56)(H2,51,52,53,57,58)/t37-,40-,41-,45-,66?/m1/s1
Synonyms: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[2-(methylamino)-2-oxoethyl]-N-(2-methyl-1-oxopropyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-(methylamino)-2-oxoethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-DMT-2'-O-NMA-G(iBu)-3'-CE-Phosphoramidite; [5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-2-N-isobutyrylguanosine]-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite

2'-O-NMA MeC(Bz) amidite

Description: 2'-O-NMA MeC(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of cytidine residues modified with 2'-O-(2-(methylamino)-2-oxoethyl) (NMA) and protected with benzoyl (Bz) into the oligonucleotide sequence. This compound is essential for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00869
CAS: 1025783-18-9
MF: C50H59N6O10P
MF: 935.03
Purity: >95%
Appearance: Off-white solid
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InChIKey: OABRWFIIVWCDDM-WBHVIXSUSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=C(C(=NC2=O)NC(=O)C=3C=CC=CC3)C)C1OCC(=O)NC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(methylamino)-2-oxoethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C50H59N6O10P/c1-33(2)56(34(3)4)67(64-29-15-28-51)66-44-42(31-63-50(37-18-13-10-14-19-37,38-20-24-40(60-7)25-21-38)39-22-26-41(61-8)27-23-39)65-48(45(44)62-32-43(57)52-6)55-30-35(5)46(54-49(55)59)53-47(58)36-16-11-9-12-17-36/h9-14,16-27,30,33-34,42,44-45,48H,15,29,31-32H2,1-8H3,(H,52,57)(H,53,54,58,59)/t42-,44-,45-,48-,67?/m1/s1
Synonyms: Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-methyl-2'-O-[2-(methylamino)-2-oxoethyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-DMT-2'-O-NMA-5-Me-C(Bz)-3'-CE-Phosphoramidite
* Only for research. Not suitable for any diagnostic or therapeutic use.

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