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Phosphoramidites

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2'-Modified Phosphoramidites
(529/529) 2'-Phosphoramidites
(27/27) 3'-Modified Phosphoramidites
(201/201) 5'-Modified Phosphoramidites
(30/30) Arabino Phosphoramidites
(23/23) Base Protected Phosphoramidites (418/418) Dye Phosphoramidites
(53/53) Label Phosphoramidites
(80/80) Linker Phosphoramidites
(85/85) Other Phosphoramidites
(97/97) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(25/25) Spacer Phosphoramidites
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1-DMTr-2-propanediyl amidite

Description: 1-DMTr-2-propanediyl amidite is a phosphoramidite used in oligonucleotide synthesis. It serves as a spacer moiety during solid-phase oligonucleotide synthesis, allowing for the attachment of nucleotide building blocks to a growing oligonucleotide chain. 1-DMTr-2-propanediyl amidite plays a crucial role in the efficient and controlled synthesis of oligonucleotides for various applications in molecular biology and biotechnology.
CAT: BRP-00841
Molecular Formula: C33H43N2O5P
Molecular Weight: 578.69
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: XCLJWHBPKOARSH-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC(C)COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC
IUPAC Name: 3-[1-[bis(4-methoxyphenyl)-phenylmethoxy]propan-2-yloxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C33H43N2O5P/c1-25(2)35(26(3)4)41(39-23-11-22-34)40-27(5)24-38-33(28-12-9-8-10-13-28,29-14-18-31(36-6)19-15-29)30-16-20-32(37-7)21-17-30/h8-10,12-21,25-27H,11,23-24H2,1-7H3
Synonyms: 1-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite

LNA MeC(pac) amidite

Description: LNA MeC(pac) amidite is a modified phosphoramidite used in oligonucleotide synthesis to introduce Locked Nucleic Acid (LNA) modifications containing a methylated cytidine (MeC) base with a phenoxyacetyl (pac) protecting group. LNA MeC(pac) amidite allows for the synthesis of oligonucleotides containing LNA modifications with methylated cytidine residues, which can be useful in various molecular biology applications, including gene expression modulation and RNA targeting.
CAT: BRP-00842
Molecular Formula: C49H56N5O10P
Molecular Weight: 905.99
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: PRARYIAJOKFQRQ-MJKSTTCNSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(5-methyl-2-oxo-4-(2-phenoxyacetamido)pyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C49H56N5O10P/c1-33(2)54(34(3)4)65(62-28-14-27-50)64-44-43-46(53-29-35(5)45(52-47(53)56)51-42(55)30-59-41-17-12-9-13-18-41)63-48(44,31-60-43)32-61-49(36-15-10-8-11-16-36,37-19-23-39(57-6)24-20-37)38-21-25-40(58-7)26-22-38/h8-13,15-26,29,33-34,43-44,46H,14,28,30-32H2,1-7H3,(H,51,52,55,56)/t43-,44+,46-,48-,65?/m1/s1
Synonyms: LNA-5-Me-C(pac) CE-Phosphoramidite; DMTr-LNA-5MeC(pac)-3-CED-phosphoramidite

MMTr PEG3 amidite

Description: MMTr PEG3 amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a linker during solid-phase oligonucleotide synthesis, allowing for the attachment of nucleotide building blocks to a growing oligonucleotide chain with the flexibility provided by the PEG3 linker. MMTr PEG3 amidite plays a crucial role in the efficient and controlled synthesis of oligonucleotides for various applications in molecular biology and biotechnology, particularly when flexibility or spacing is desired.
CAT: BRP-00843
Molecular Formula: C35H47N2O6P
Molecular Weight: 622.74
Purity: >95%
Appearance: Colourless oily matter
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Storage: Store at -20 °C
InChIKey: FUFCVFZHFJGQTH-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OCCOCCOCCOC(C(C=C1)=CC=C1OC)(C2=CC=CC=C2)C3=CC=CC=C3)N(C(C)C)C(C)C
IUPAC Name: 2-cyanoethyl (2-(2-(2-((4-methoxyphenyl)diphenylmethoxy)ethoxy)ethoxy)ethyl) diisopropylphosphoramidite
InChI: InChI=1S/C35H47N2O6P/c1-29(2)37(30(3)4)44(42-22-12-21-36)43-28-26-40-24-23-39-25-27-41-35(31-13-8-6-9-14-31,32-15-10-7-11-16-32)33-17-19-34(38-5)20-18-33/h6-11,13-20,29-30H,12,22-28H2,1-5H3

LNA MeC(dmf) amidite

Description: LNA MeC(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis to introduce Locked Nucleic Acid (LNA) modifications containing a methylated cytidine (MeC) base with a dimethylformamidine (dmf) protecting group. LNA MeC(dmf) amidite allows for the synthesis of oligonucleotides containing LNA modifications with methylated cytidine residues, which can be useful in various molecular biology applications, including gene expression modulation and RNA targeting.
CAT: BRP-00844
Molecular Formula: C44H55N6O8P
Molecular Weight: 826.93
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: ALMLYLOSIBVJJH-JHFWARBRSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(4-(((dimethylamino)methylene)amino)-5-methyl-2-oxopyrimidin-1(2H)-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C44H55N6O8P/c1-30(2)50(31(3)4)59(56-25-13-24-45)58-39-38-41(49-26-32(5)40(47-42(49)51)46-29-48(6)7)57-43(39,27-54-38)28-55-44(33-14-11-10-12-15-33,34-16-20-36(52-8)21-17-34)35-18-22-37(53-9)23-19-35/h10-12,14-23,26,29-31,38-39,41H,13,25,27-28H2,1-9H3/t38-,39+,41-,43-,59?/m1/s1
Synonyms: LNA-5-Me-C(dmf) CE-Phosphoramidite; DMTr-LNA-5MeC(dmf)-3-CED-phosphoramidite

LNA A(dmf) amidite

Description: LNA A(dmf) amidite is a modified phosphoramidite used in oligonucleotide synthesis to introduce Locked Nucleic Acid (LNA) modifications containing a dimethylformamidine (dmf) protecting group on adenine (A) nucleobase. LNA A(dmf) amidite allows for the synthesis of oligonucleotides containing LNA modifications with adenine residues protected by dimethylformamidine, which can be useful in various molecular biology applications, including gene expression modulation and RNA targeting.
CAT: BRP-00845
Molecular Formula: C44H53N8O7P
Molecular Weight: 836.93
Purity: >98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: VCQRTYMXOYNMDL-IPPGHXGVSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-(6-(((dimethylamino)methylene)amino)-9H-purin-9-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C44H53N8O7P/c1-30(2)52(31(3)4)60(57-24-12-23-45)59-39-38-42(51-29-48-37-40(49-28-50(5)6)46-27-47-41(37)51)58-43(39,25-55-38)26-56-44(32-13-10-9-11-14-32,33-15-19-35(53-7)20-16-33)34-17-21-36(54-8)22-18-34/h9-11,13-22,27-31,38-39,42H,12,24-26H2,1-8H3/t38-,39+,42-,43-,60?/m1/s1
Synonyms: LNA A(dmf) CE-Phosphoramidite; DMTr-LNA-A(dmf)-3-CED-phosphoramidite

MMTr C3 amine amidite

Description: MMTr C3 amine amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a linker during solid-phase oligonucleotide synthesis, allowing for the attachment of nucleotide building blocks to a growing oligonucleotide chain. MMTr C3 amine amidite plays a crucial role in the efficient and controlled synthesis of oligonucleotides for various applications in molecular biology and biotechnology.
CAT: BRP-00846
CAS: 119462-97-4
Molecular Formula: C32H42N3O3P
Molecular Weight: 547.68
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
InChIKey: ZDCIPDOLNLJZRB-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCNC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=C(C=C3)OC)OCCC#N
IUPAC Name: 3-[[di(propan-2-yl)amino]-[3-[[(4-methoxyphenyl)-diphenylmethyl]amino]propoxy]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C32H42N3O3P/c1-26(2)35(27(3)4)39(37-24-12-22-33)38-25-13-23-34-32(28-14-8-6-9-15-28,29-16-10-7-11-17-29)30-18-20-31(36-5)21-19-30/h6-11,14-21,26-27,34H,12-13,23-25H2,1-5H3
Synonyms: 2-Cyanoethyl 3-[[(4-methoxyphenyl)diphenylmethyl]amino]propyl N,N-bis(1-methylethyl)phosphoramidite; 2-cyanoethyl (3-(((4-methoxyphenyl)diphenylmethyl)amino)propyl) diisopropylphosphoramidite; MMTr C3 linker Phosphoramidite; Monomethoxytrityl-propylamine-linker Phosphoramidite

(S)-BuNA U amidite

Description: (S)-BuNA U amidite is a modified phosphoramidite used in oligonucleotide synthesis. It is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00847
CAS: 1452390-83-8
Molecular Formula: C38H47N4O7P
Molecular Weight: 702.79
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: GMUTXDAJRYBBQH-NMIPJSAASA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: N#CCCOP(OC(CN1C=CC(=O)NC1=O)CCOC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N(C(C)C)C(C)C
IUPAC Name: (S)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-1-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)butan-2-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C38H47N4O7P/c1-28(2)42(29(3)4)50(48-25-10-23-39)49-35(27-41-24-21-36(43)40-37(41)44)22-26-47-38(30-11-8-7-9-12-30,31-13-17-33(45-5)18-14-31)32-15-19-34(46-6)20-16-32/h7-9,11-21,24,28-29,35H,10,22,25-27H2,1-6H3,(H,40,43,44)/t35-,50?/m0/s1
Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S)-3-[bis(4-methoxyphenyl)phenylmethoxy]-1-[(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methyl]propyl 2-cyanoethyl ester; (1S)-3-[Bis(4-methoxyphenyl)phenylmethoxy]-1-[(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methyl]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite

(S)-BuNA C(Bz) amidite

Description: (S)-BuNA C(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00848
CAS: 1452390-96-3
Molecular Formula: C45H52N5O7P
Molecular Weight: 805.91
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: OZJXSCDXPZBOPH-ONFVIWAESA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC(CCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)CN4C=CC(=NC4=O)NC(=O)C5=CC=CC=C5
IUPAC Name: N-[1-[(2S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxybutyl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C45H52N5O7P/c1-33(2)50(34(3)4)58(56-30-13-28-46)57-41(32-49-29-26-42(48-44(49)52)47-43(51)35-14-9-7-10-15-35)27-31-55-45(36-16-11-8-12-17-36,37-18-22-39(53-5)23-19-37)38-20-24-40(54-6)25-21-38/h7-12,14-26,29,33-34,41H,13,27,30-32H2,1-6H3,(H,47,48,51,52)/t41-,58?/m0/s1
Synonyms: (S)-1-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)butan-2-yl (2-cyanoethyl) diisopropylphosphoramidite

(S)-BuNA A(Bz) amidite

Description: (S)-BuNA A(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00849
CAS: 1452390-99-6
Molecular Formula: C46H52N7O6P
Molecular Weight: 829.94
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: QOLFEXISLSPHKS-CTHPAJCMSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC(CCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)CN4C=NC5=C(N=CN=C54)NC(=O)C6=CC=CC=C6
IUPAC Name: N-[9-[(2S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxybutyl]purin-6-yl]benzamide
InChI: InChI=1S/C46H52N7O6P/c1-33(2)53(34(3)4)60(58-28-13-27-47)59-41(30-52-32-50-42-43(48-31-49-44(42)52)51-45(54)35-14-9-7-10-15-35)26-29-57-46(36-16-11-8-12-17-36,37-18-22-39(55-5)23-19-37)38-20-24-40(56-6)25-21-38/h7-12,14-25,31-34,41H,13,26,28-30H2,1-6H3,(H,48,49,51,54)/t41-,60?/m0/s1
Synonyms: (S)-1-(6-benzamido-9H-purin-9-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)butan-2-yl (2-cyanoethyl) diisopropylphosphoramidite

(S)-BuNA G(iBu) amidite

Description: (S)-BuNA G(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00850
Molecular Formula: C43H54N7O7P
Molecular Weight: 811.92
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: JDXNYQOHJJNIOS-BVARLVFGSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2CC(CCOC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxybutyl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C43H54N7O7P/c1-29(2)40(51)47-42-46-39-38(41(52)48-42)45-28-49(39)27-37(57-58(56-25-12-24-44)50(30(3)4)31(5)6)23-26-55-43(32-13-10-9-11-14-32,33-15-19-35(53-7)20-16-33)34-17-21-36(54-8)22-18-34/h9-11,13-22,28-31,37H,12,23,25-27H2,1-8H3,(H2,46,47,48,51,52)/t37-,58?/m0/s1
Synonyms: (S)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-1-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)butan-2-yl (2-cyanoethyl) diisopropylphosphoramidite

3'-O-Me-U-2'-phosphoramidite

Description: 3'-O-Me-U-2'-phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 3'-O-methyluridine residues into the oligonucleotide sequence. 3'-O-Me-U-2'-phosphoramidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00851
CAS: 179479-05-1
Molecular Formula: C40H49N4O9P
Molecular Weight: 760.83
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: FPRLFGWVAXFXTL-XKZJCBTISA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OC
IUPAC Name: 3-[[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-2-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C40H49N4O9P/c1-27(2)44(28(3)4)54(51-25-11-23-41)53-37-36(49-7)34(52-38(37)43-24-22-35(45)42-39(43)46)26-50-40(29-12-9-8-10-13-29,30-14-18-32(47-5)19-15-30)31-16-20-33(48-6)21-17-31/h8-10,12-22,24,27-28,34,36-38H,11,25-26H2,1-7H3,(H,42,45,46)/t34-,36-,37-,38-,54?/m1/s1
Synonyms: 3'-OMe U 2'-amidite; 5'-O-(4,4'-Dimethoxytrityl)-3'-O-methyl-uridine-2'-cyanoethyl phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-DMTr-3'-O-methyluridine-2'-CED-phosphoramidite; 3'-OMe-U Phosphoramidite; 5'-O-DMTr-3'-O-methyluridine-3'-CED-phosphoramidite; 3'-O-Methyl Uridine CED phosphoramidite

3'-O-Me-C(Ac)-2'-phosphoramidite

Description: 3'-O-Me-C(Ac)-2'-phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 3'-O-methylcytidine residues with acetyl protection into the oligonucleotide sequence. 3'-O-Me-C(Ac)-2'-phosphoramidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00852
Molecular Formula: C42H52N5O9P
Molecular Weight: 801.88
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: GATGWWGSSVDAEU-UAQIPLLRSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OC
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide
InChI: InChI=1S/C42H52N5O9P/c1-28(2)47(29(3)4)57(54-26-12-24-43)56-39-38(52-8)36(55-40(39)46-25-23-37(44-30(5)48)45-41(46)49)27-53-42(31-13-10-9-11-14-31,32-15-19-34(50-6)20-16-32)33-17-21-35(51-7)22-18-33/h9-11,13-23,25,28-29,36,38-40H,12,26-27H2,1-8H3,(H,44,45,48,49)/t36-,38-,39-,40-,57?/m1/s1
Synonyms: (2R,3R,4R,5R)-2-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 3'-OMe C(Ac) 2'-amidite; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methyl-cytidine-2'-cyanoethyl phosphoramidite; 3'-OMe-C(Ac) Phosphoramidite

3'-O-Me-C(Bz)-2'-phosphoramidite

Description: 3'-O-Me-C(Bz)-2'-phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 3'-O-methylcytidine residues with benzoyl protection into the oligonucleotide sequence. 3'-O-Me-C(Bz)-2'-phosphoramidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00853
CAS: 179479-03-9
Molecular Formula: C47H54N5O9P
Molecular Weight: 863.95
Purity: >95%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: BENGZEFYMXNUAR-VKBHKTMGSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OC
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-methoxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C47H54N5O9P/c1-32(2)52(33(3)4)62(59-30-14-28-48)61-43-42(57-7)40(60-45(43)51-29-27-41(50-46(51)54)49-44(53)34-15-10-8-11-16-34)31-58-47(35-17-12-9-13-18-35,36-19-23-38(55-5)24-20-36)37-21-25-39(56-6)26-22-37/h8-13,15-27,29,32-33,40,42-43,45H,14,30-31H2,1-7H3,(H,49,50,53,54)/t40-,42-,43-,45-,62?/m1/s1
Synonyms: 3'-OMe C(Bz) 2'-amidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N4-Bz-5'-O-DMTr-3'-O-methylcytidine-2'-CED-phosphoramidite; 3'-O-Methyl Cytidine (n-bz) CED phosphoramidite

3'-O-Me-G(iBu)-2'-phosphoramidite

Description: 3'-O-Me-G(iBu)-2'-phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 3'-O-methylguanosine residues with isobutyl protection into the oligonucleotide sequence. 3'-O-Me-G(iBu)-2'-phosphoramidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00854
CAS: 179479-04-0
Molecular Formula: C45H56N7O9P
Molecular Weight: 869.96
Purity: >95%
Appearance: Off-white solid
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InChIKey: POYXHFZLQWXZTI-MLLDKZSOSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OC)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(61-62(59-25-13-24-46)52(29(3)4)30(5)6)38(57-9)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/m1/s1
Synonyms: 3'-OMe G(iBu) 2'-amidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-DMTr-N2-iso-butyroyl-3'-O-methylguanosine-2'-CED-phosphoramidite; 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)guanosine, 2'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-3'-O-methylguanosine-2'-cyanoethyl phosphoramidite; 3'-O-Methyl Guanosine (n-ibu) CED phosphoramidite

2'-TFA-AE A(iBu) amidite

Description: 2'-TFA-AE A(iBu) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of adenine residues with 2'-trifluoroacetyl modification and isobutyl protection into the oligonucleotide sequence. 2'-TFA-AE A(iBu) amidite is used in the synthesis of modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00855
CAS: 853748-67-1
Molecular Formula: C48H58F3N8O9P
Molecular Weight: 979.01
Purity: >95%
Appearance: Off-white solid
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InChIKey: PDBNCRNDNUXWIB-KUGYPCBWSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCNC(=O)C(F)(F)F
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-[(2,2,2-trifluoroacetyl)amino]ethoxy]oxolan-2-yl]purin-6-yl]-2-methylpropanamide
InChI: InChI=1S/C48H58F3N8O9P/c1-30(2)44(60)57-42-39-43(55-28-54-42)58(29-56-39)45-41(64-26-24-53-46(61)48(49,50)51)40(68-69(66-25-12-23-52)59(31(3)4)32(5)6)38(67-45)27-65-47(33-13-10-9-11-14-33,34-15-19-36(62-7)20-16-34)35-17-21-37(63-8)22-18-35/h9-11,13-22,28-32,38,40-41,45H,12,24-27H2,1-8H3,(H,53,61)(H,54,55,57,60)/t38-,40-,41-,45-,69?/m1/s1
Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-[2-[(trifluoroacetyl)amino]ethyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-isobutyramido-9H-purin-9-yl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-O-(TFA-aminoethyl)-A(iBu) 3'-CE Phosphoramidite

2'-TFA-AE G(iBu) amidite

Description: 2'-TFA-AE G(iBu) amidite is a modified phosphoramidite utilized in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of guanine residues with 2'-trifluoroacetyl modification and isobutyl protection into the oligonucleotide sequence. This compound is valuable for synthesizing modified oligonucleotides for diverse applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00856
CAS: 853748-79-5
Molecular Formula: C48H58F3N8O10P
Molecular Weight: 995.01
Purity: >95%
Appearance: Off-white solid
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InChIKey: XIQAQHLVRVPSFM-DYTYPCPCSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCNC(=O)C(F)(F)F
IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-[(2,2,2-trifluoroacetyl)amino]ethoxy]oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
InChI: InChI=1S/C48H58F3N8O10P/c1-29(2)42(60)56-46-55-41-38(43(61)57-46)54-28-58(41)44-40(65-26-24-53-45(62)48(49,50)51)39(69-70(67-25-12-23-52)59(30(3)4)31(5)6)37(68-44)27-66-47(32-13-10-9-11-14-32,33-15-19-35(63-7)20-16-33)34-17-21-36(64-8)22-18-34/h9-11,13-22,28-31,37,39-40,44H,12,24-27H2,1-8H3,(H,53,62)(H2,55,56,57,60,61)/t37-,39-,40-,44-,70?/m1/s1
Synonyms: (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-3,6-dihydro-9H-purin-9-yl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-O-(TFA-aminoethyl)-G(iBu) 3'-CE Phosphoramidite

2'-TFA-AE U amidite

Description: 2'-TFA-AE U amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of uracil residues with 2'-trifluoroacetyl modification into the oligonucleotide sequence. This compound is essential for synthesizing modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00857
CAS: 853748-56-8
Molecular Formula: C43H51F3N5O10P
Molecular Weight: 885.87
Purity: >95%
Appearance: Off-white solid
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InChIKey: YBHWJTBVGJAGKI-BVGHISPXSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCNC(=O)C(F)(F)F)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
IUPAC Name: N-[2-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxyethyl]-2,2,2-trifluoroacetamide
InChI: InChI=1S/C43H51F3N5O10P/c1-28(2)51(29(3)4)62(59-25-10-22-47)61-37-35(60-39(50-24-21-36(52)49-41(50)54)38(37)57-26-23-48-40(53)43(44,45)46)27-58-42(30-11-8-7-9-12-30,31-13-17-33(55-5)18-14-31)32-15-19-34(56-6)20-16-32/h7-9,11-21,24,28-29,35,37-39H,10,23,25-27H2,1-6H3,(H,48,53)(H,49,52,54)/t35-,37-,38-,39-,62?/m1/s1
Synonyms: 5'-O-DMT-2'-O-(TFA-aminoethyl)-rU 3'-CE Phosphoramidite; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

2'-TFA-AE G(Ac) amidite

Description: 2'-TFA-AE G(Ac) amidite is a modified phosphoramidite employed in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of guanine residues with 2'-trifluoroacetyl modification and acetyl protection into the oligonucleotide sequence. This compound is crucial for synthesizing modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00858
CAS: 911110-89-9
Molecular Formula: C46H54F3N8O10P
Molecular Weight: 966.95
Purity: >95%
Appearance: Off-white solid
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InChIKey: MHPBJBUMRBEOBZ-DZAGQWDNSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCNC(=O)C(F)(F)F)N2C=NC3=C2N=C(NC3=O)NC(=O)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC
IUPAC Name: N-[2-[(2R,3R,4R,5R)-2-(2-acetamido-6-oxo-1H-purin-9-yl)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-3-yl]oxyethyl]-2,2,2-trifluoroacetamide
InChI: InChI=1S/C46H54F3N8O10P/c1-28(2)57(29(3)4)68(65-24-11-22-50)67-38-36(26-64-45(31-12-9-8-10-13-31,32-14-18-34(61-6)19-15-32)33-16-20-35(62-7)21-17-33)66-42(39(38)63-25-23-51-43(60)46(47,48)49)56-27-52-37-40(56)54-44(53-30(5)58)55-41(37)59/h8-10,12-21,27-29,36,38-39,42H,11,23-26H2,1-7H3,(H,51,60)(H2,53,54,55,58,59)/t36-,38-,39-,42-,68?/m1/s1
Synonyms: Guanosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[2-[(trifluoroacetyl)amino]ethyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R)-5-(2-acetamido-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-O-(TFA-aminoethyl)-G(Ac) 3'-CE Phosphoramidite

2'-TFA-AE MeC(Bz) amidite

Description: 2'-TFA-AE MeC(Bz) amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, allowing the incorporation of 5-methylcytidine residues with 2'-trifluoroacetyl modification and benzoyl protection into the oligonucleotide sequence. This compound is essential for synthesizing modified oligonucleotides for various applications in molecular biology, diagnostics, and therapeutics.
CAT: BRP-00859
CAS: 911110-81-1
Molecular Formula: C51H58F3N6O10P
Molecular Weight: 1003.03
Purity: >95%
Appearance: Off-white solid
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InChIKey: SXKUHFATFPKDLA-DCGXNHRISA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)OCCNC(=O)C(F)(F)F
IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-[2-[(2,2,2-trifluoroacetyl)amino]ethoxy]oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide
InChI: InChI=1S/C51H58F3N6O10P/c1-33(2)60(34(3)4)71(68-29-14-27-55)70-43-42(32-67-50(37-17-12-9-13-18-37,38-19-23-40(64-6)24-20-38)39-21-25-41(65-7)26-22-39)69-47(44(43)66-30-28-56-48(62)51(52,53)54)59-31-35(5)45(58-49(59)63)57-46(61)36-15-10-8-11-16-36/h8-13,15-26,31,33-34,42-44,47H,14,28-30,32H2,1-7H3,(H,56,62)(H,57,58,61,63)/t42-,43-,44-,47-,71?/m1/s1
Synonyms: 5'-O-DMT-2'-O-(TFA-aminoethyl)-MeC(Bz) 3'-CE Phosphoramidite; (2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-(2,2,2-trifluoroacetamido)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

2'-(PHT)aminoethyl U amidite

Description: 2'-(PHT)aminoethyl U amidite is a modified phosphoramidite used in oligonucleotide synthesis. It serves as a building block during solid-phase oligonucleotide synthesis, enabling the incorporation of uracil residues with a 2'-(PHT)aminoethyl modification into the oligonucleotide sequence. This compound is important for synthesizing oligonucleotides with specific modifications, which can be utilized in various applications such as molecular biology research, diagnostics, and therapeutics.
CAT: BRP-00860
CAS: 1037523-39-9
Molecular Formula: C49H54N5O11P
Molecular Weight: 919.97
Purity: >95%
Appearance: Off-white solid
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InChIKey: VIVGUNXKRHKESW-FEVKEASNSA-N
Solubility: Soluble in Acetonitrile, DMF
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCN2C(=O)C3=CC=CC=C3C2=O)N4C=CC(=O)NC4=O)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC
IUPAC Name: 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-(1,3-dioxoisoindol-2-yl)ethoxy]-5-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C49H54N5O11P/c1-32(2)54(33(3)4)66(63-29-12-26-50)65-43-41(31-62-49(34-13-8-7-9-14-34,35-17-21-37(59-5)22-18-35)36-19-23-38(60-6)24-20-36)64-47(53-27-25-42(55)51-48(53)58)44(43)61-30-28-52-45(56)39-15-10-11-16-40(39)46(52)57/h7-11,13-25,27,32-33,41,43-44,47H,12,28-31H2,1-6H3,(H,51,55,58)/t41-,43-,44-,47-,66?/m1/s1
Synonyms: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-(PHT)aminoethyl-U 3'-CE Phosphoramidite
* Only for research. Not suitable for any diagnostic or therapeutic use.

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