Phosphoramidites - RNA / BOC Sciences

5'-DMT-2'-OMe-A(Bz)-3'-PS-Phosphoramidite

Description: 5'-DMT-2'-OMe-A(Bz)-3'-PS-Phosphoramidite is a specialized nucleotide compound utilized in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and an adenine base modified with a benzoyl (Bz) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite enables controlled addition during synthesis and offers enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It finds applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.

CAT: BRP-00403

MF: C52H53N6O8PS2

MF: 985.12

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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InChIKey: CLDYJLPUISOESS-LTMMGAFGSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N8CCCC8)SCCSC(=O)C9=CC=CC=C9

IUPAC Name: S-[2-[[(2R,3R,4R,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate

InChI: InChI=1S/C52H53N6O8PS2/c1-61-41-25-21-39(22-26-41)52(38-19-11-6-12-20-38,40-23-27-42(62-2)28-24-40)64-33-43-45(66-67(57-29-13-14-30-57)69-32-31-68-51(60)37-17-9-5-10-18-37)46(63-3)50(65-43)58-35-55-44-47(53-34-54-48(44)58)56-49(59)36-15-7-4-8-16-36/h4-12,15-28,34-35,43,45-46,50H,13-14,29-33H2,1-3H3,(H,53,54,56,59)/t43-,45-,46-,50-,67?/m1/s1

Synonyms: S-(2-(((((2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphino)thio)ethyl) benzothioate; DMT-2'-OMe-A(Bz)-3'-PS; [N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-adenosine]-3'-[S-(β-(Benzoylmercapto)ethyl) Pyrrolidino Thiophosphoroamidite]; 2'-OMe-A-Thiophosphoramidite; 5'-Dimethoxytrityl-N-benzoyl-Adenosine, 2'-O-methyl, 3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite

5'-DMT-2'-OMe-G(iBu)-3'-PS-Phosphoramidite

Description: 5'-DMT-2'-OMe-G(iBu)-3'-PS-Phosphoramidite is a specialized nucleotide compound employed in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and a guanine base modified with an isobutyl (iBu) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite enables controlled addition during synthesis and offers enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It finds applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.

CAT: BRP-00404

MF: C49H55N6O9PS2

MF: 967.11

Purity: ≥90% by HPLC

Appearance: White to yellow powder

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InChIKey: HZMNPGZRUUSWOU-VKFKYRIUSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N7CCCC7)SCCSC(=O)C8=CC=CC=C8)OC

IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxy-5-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate

InChI: InChI=1S/C49H55N6O9PS2/c1-32(2)44(56)52-48-51-43-40(45(57)53-48)50-31-55(43)46-42(61-5)41(64-65(54-26-12-13-27-54)67-29-28-66-47(58)33-14-8-6-9-15-33)39(63-46)30-62-49(34-16-10-7-11-17-34,35-18-22-37(59-3)23-19-35)36-20-24-38(60-4)25-21-36/h6-11,14-25,31-32,39,41-42,46H,12-13,26-30H2,1-5H3,(H2,51,52,53,56,57)/t39-,41-,42-,46-,65?/m1/s1

Synonyms: DMT-2'-OMe-G(iBu)-3'-PS; [N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-guanosine]-3'-[S-(β-(Benzoylmercapto)ethyl)pyrrolidino Thiophosphoroamidite]; S-(2-(((((2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1H-purin-9(6H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphino)thio)ethyl) benzothioate; 2'-OMe-G-Thiophosphoramidite; 5'-Dimethoxytrityl-N-isobutyryl-Guanosine, 2'-O-methyl,3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite

5'-DMT-2'-O-MOE-G(iBu)-3'-PS-Phosphoramidite

Description: 5'-DMT-2'-O-MOE-G(iBu)-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methoxyethyl (MOE) modification on the ribose sugar, and a guanine base modified with an isobutyl (iBu) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and provides enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It is utilized in various molecular biology research applications, including gene synthesis, RNA interference, and nucleic acid probe development.

CAT: BRP-00405

CAS: 2360826-78-2

MF: C51H59N6O10PS2

MF: 1011.16

Purity: ≥90% by HPLC

Appearance: White to yellow powder

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InChIKey: HDXVTGDRJQVYMX-MGIZDRFQSA-N

CanonicalSMILES: O=C1N=C(NC(=O)C(C)C)NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(OP(SCCSC(=O)C=7C=CC=CC7)N8CCCC8)C3OCCOC

IUPAC Name: S-(2-(((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate

InChI: InChI=1S/C51H59N6O10PS2/c1-34(2)46(58)54-50-53-45-42(47(59)55-50)52-33-57(45)48-44(64-29-28-61-3)43(67-68(56-26-12-13-27-56)70-31-30-69-49(60)35-14-8-6-9-15-35)41(66-48)32-65-51(36-16-10-7-11-17-36,37-18-22-39(62-4)23-19-37)38-20-24-40(63-5)25-21-38/h6-11,14-25,33-34,41,43-44,48H,12-13,26-32H2,1-5H3,(H2,53,54,55,58,59)/t41-,43-,44-,48-,68?/m1/s1

Synonyms: [N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-guanosine]-3'-[S-(β-(Benzoylmercapto)ethyl) Pyrrolidino Thiophosphoroamidite]

5'-DMT-2'-O-MOE-A(Bz)-3'-PS-Phosphoramidite

Description: 5'-DMT-2'-O-MOE-A(Bz)-3'-PS-Phosphoramidite is a specialized nucleotide compound utilized in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methoxyethyl (MOE) modification on the ribose sugar, and an adenine base modified with a benzoyl (Bz) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite enables controlled addition during synthesis and offers enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It finds applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.

CAT: BRP-00406

CAS: 2360826-72-6

MF: C54H57N6O9PS2

MF: 1029.18

Purity: ≥90% by HPLC

Appearance: White to yellow powder

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InChIKey: OKYFNXWXBWXJHI-QRWWDSLFSA-N

CanonicalSMILES: O=C(SCCSP(OC1C(OC(N2C=NC=3C(=NC=NC32)NC(=O)C=4C=CC=CC4)C1OCCOC)COC(C=5C=CC=CC5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)N8CCCC8)C=9C=CC=CC9

IUPAC Name: S-(2-(((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate

InChI: InChI=1S/C54H57N6O9PS2/c1-63-31-32-66-48-47(69-70(59-29-13-14-30-59)72-34-33-71-53(62)39-17-9-5-10-18-39)45(68-52(48)60-37-57-46-49(55-36-56-50(46)60)58-51(61)38-15-7-4-8-16-38)35-67-54(40-19-11-6-12-20-40,41-21-25-43(64-2)26-22-41)42-23-27-44(65-3)28-24-42/h4-12,15-28,36-37,45,47-48,52H,13-14,29-35H2,1-3H3,(H,55,56,58,61)/t45-,47-,48-,52-,70?/m1/s1

Synonyms: [N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine]-3'-[S-(β-(Benzoylmercapto)ethyl) Pyrrolidino Thiophosphoroamidite]

5'-DMT-2'-O-MOE-5-Me-C(Bz)-3'-PS-Phosphoramidite

Description: 5'-DMT-2'-O-MOE-5-Me-C(Bz)-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methoxyethyl (MOE) modification on the ribose sugar, and a 5-methylcytosine base modified with a benzoyl (Bz) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite enables controlled addition during synthesis and provides enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It is utilized in various molecular biology research applications, including gene synthesis, RNA interference, and nucleic acid probe development.

CAT: BRP-00407

CAS: 2360826-74-8

MF: C54H59N4O10PS2

MF: 1019.18

Purity: ≥90% by HPLC

Appearance: White to yellow powder

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InChIKey: JHTAVHWNDBSHFT-GDWCHFCQSA-N

CanonicalSMILES: O=C1N=C(NC(=O)C=2C=CC=CC2)C(=CN1C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(OP(SCCSC(=O)C=7C=CC=CC7)N8CCCC8)C3OCCOC)C

IUPAC Name: S-(2-(((((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate

InChI: InChI=1S/C54H59N4O10PS2/c1-38-36-58(53(61)56-49(38)55-50(59)39-16-8-5-9-17-39)51-48(65-33-32-62-2)47(68-69(57-30-14-15-31-57)71-35-34-70-52(60)40-18-10-6-11-19-40)46(67-51)37-66-54(41-20-12-7-13-21-41,42-22-26-44(63-3)27-23-42)43-24-28-45(64-4)29-25-43/h5-13,16-29,36,46-48,51H,14-15,30-35,37H2,1-4H3,(H,55,56,59,61)/t46-,47-,48-,51-,69?/m1/s1

Synonyms: [N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-5-methyl-cytidine]-3'-[S-(β-(Benzoylmercapto)ethyl) Pyrrolidino Thiophosphoroamidite]

5'-DMT-2'-OMe-5-Me-C(Bz)-3'-PS-Phosphoramidite

Description: 5'-DMT-2'-OMe-5-Me-C(Bz)-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It consists of a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and a 5-methylcytosine base modified with a benzoyl (Bz) group. Additionally, it features a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and enhances stability, making it suitable for applications such as gene synthesis, RNA interference, and nucleic acid probe development in molecular biology research.

CAT: BRP-00408

MF: C52H55N4O9PS2

MF: 975.12

Purity: ≥90% by HPLC

Appearance: White to yellow powder

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InChIKey: DOVLPDMECIOKGA-BZPNBFHRSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N7CCCC7)SCCSC(=O)C8=CC=CC=C8)OC

IUPAC Name: S-[2-[[(2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate

InChI: InChI=1S/C52H55N4O9PS2/c1-36-34-56(51(59)54-47(36)53-48(57)37-16-8-5-9-17-37)49-46(62-4)45(65-66(55-30-14-15-31-55)68-33-32-67-50(58)38-18-10-6-11-19-38)44(64-49)35-63-52(39-20-12-7-13-21-39,40-22-26-42(60-2)27-23-40)41-24-28-43(61-3)29-25-41/h5-13,16-29,34,44-46,49H,14-15,30-33,35H2,1-4H3,(H,53,54,57,59)/t44-,45-,46-,49-,66?/m1/s1

Synonyms: [N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyl-cytidine]-3'-[S-(β-(Benzoylmercapto)ethyl) Pyrrolidino Thiophosphoroamidite]; S-(2-(((((2R,3R,4R,5R)-5-(4-Benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphino)thio)ethyl) benzothioate

5'-DMT-2'-OMe-C(Ac)-3'-PS-Phosphoramidite

Description: 5'-DMT-2'-OMe-C(Ac)-3'-PS-Phosphoramidite is a specialized nucleotide compound utilized in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and a cytidine base modified with an acetyl (Ac) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite enables controlled addition during synthesis and provides enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It is employed in various molecular biology research applications, including gene synthesis, RNA interference, and nucleic acid probe development.

CAT: BRP-00409

MF: C46H51N4O9PS2

MF: 899.03

Purity: ≥90% by HPLC

Appearance: White to yellow powder

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InChIKey: CNCXGATYHORASL-SRYSXPHVSA-N

CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7)OC

IUPAC Name: S-[2-[[(2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate

InChI: InChI=1S/C46H51N4O9PS2/c1-32(51)47-40-25-28-50(45(53)48-40)43-42(56-4)41(59-60(49-26-11-12-27-49)62-30-29-61-44(52)33-13-7-5-8-14-33)39(58-43)31-57-46(34-15-9-6-10-16-34,35-17-21-37(54-2)22-18-35)36-19-23-38(55-3)24-20-36/h5-10,13-25,28,39,41-43H,11-12,26-27,29-31H2,1-4H3,(H,47,48,51,53)/t39-,41-,42-,43-,60?/m1/s1

Synonyms: DMT-2'-OMe-C(Ac)-3'-PS; [N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyl-cytidine]-3'-[S-(β-(Benzoylmercapto)ethyl) Pyrrolidino Thiophosphoroamidite]; S-(2-(((((2R,3R,4R,5R)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphino)thio)ethyl) benzothioate; 2'-OMe-C-Thiophosphoramidite; 5'-Dimethoxytrityl-N-acetyl-Cytidine, 2'-O-methyl,3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite

5'-DMT-2'-OMe-U-3'-PS-Phosphoramidite

Description: 5'-DMT-2'-OMe-U-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It comprises a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and a uridine base. Additionally, it contains a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and enhances stability, making it suitable for various applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.

CAT: BRP-00410

MF: C44H48N3O9PS2

MF: 857.97

Purity: ≥90% by HPLC

Appearance: White to yellow powder

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InChIKey: WOJBALAHZBVIKR-QBLJBMGASA-N

CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7

IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate

InChI: InChI=1S/C44H48N3O9PS2/c1-51-35-20-16-33(17-21-35)44(32-14-8-5-9-15-32,34-18-22-36(52-2)23-19-34)54-30-37-39(40(53-3)41(55-37)47-27-24-38(48)45-43(47)50)56-57(46-25-10-11-26-46)59-29-28-58-42(49)31-12-6-4-7-13-31/h4-9,12-24,27,37,39-41H,10-11,25-26,28-30H2,1-3H3,(H,45,48,50)/t37-,39-,40-,41-,57?/m1/s1

Synonyms: DMT-2'-OMe-U-3'-PS; [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-uridine]-3'-[S-(β-(Benzoylmercapto)ethyl)Pyrrolidino Thiophosphoroamidite]; S-(2-(((((2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphino)thio)ethyl) benzothioate; 2'-OMe-U-Thiophosphoramidite; 5'-Dimethoxytrityl-Uridine, 2'-O-methyl, 3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite

5'-DMT-2'-OMe-5-Me-U-3'-PS-Phosphoramidite

Description: 5'-DMT-2'-OMe-5-Me-U-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It consists of a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and a 5-methyluridine base. Additionally, it features a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and enhances stability, making it suitable for various applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.

CAT: BRP-00411

MF: C45H50N3O9PS2

MF: 872.00

Purity: ≥90% by HPLC

Appearance: White to yellow powder

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InChIKey: IWVGGTNZQUQJEA-MWUWPPOZSA-N

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7)OC

IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate

InChI: InChI=1S/C45H50N3O9PS2/c1-31-29-48(44(51)46-41(31)49)42-40(54-4)39(57-58(47-25-11-12-26-47)60-28-27-59-43(50)32-13-7-5-8-14-32)38(56-42)30-55-45(33-15-9-6-10-16-33,34-17-21-36(52-2)22-18-34)35-19-23-37(53-3)24-20-35/h5-10,13-24,29,38-40,42H,11-12,25-28,30H2,1-4H3,(H,46,49,51)/t38-,39-,40-,42-,58?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyl-uridine]-3'-[S-(β-(Benzoylmercapto)ethyl)Pyrrolidino Thiophosphoroamidite]; S-(2-(((((2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphino)thio)ethyl) benzothioate

5'-DMT-2'-O-MOE-5-Me-U-3'-PS-Phosphoramidite

Description: 5'-DMT-2'-O-MOE-5-Me-U-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It comprises a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methoxyethyl (MOE) modification on the ribose sugar, and a 5-methyluridine base. Additionally, it contains a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and enhances stability, making it suitable for various applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.

CAT: BRP-00412

CAS: 2360826-70-4

MF: C47H54N3O10PS2

MF: 916.05

Purity: ≥90% by HPLC

Appearance: White to yellow powder

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InChIKey: VCDBYBSSVSRJPT-OMRXSTERSA-N

CanonicalSMILES: O=C(SCCSP(OC1C(OC(N2C=C(C(=O)NC2=O)C)C1OCCOC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N6CCCC6)C=7C=CC=CC7

IUPAC Name: S-(2-(((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate

InChI: InChI=1S/C47H54N3O10PS2/c1-33-31-50(46(53)48-43(33)51)44-42(57-28-27-54-2)41(60-61(49-25-11-12-26-49)63-30-29-62-45(52)34-13-7-5-8-14-34)40(59-44)32-58-47(35-15-9-6-10-16-35,36-17-21-38(55-3)22-18-36)37-19-23-39(56-4)24-20-37/h5-10,13-24,31,40-42,44H,11-12,25-30,32H2,1-4H3,(H,48,51,53)/t40-,41-,42-,44-,61?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-5-methyl-uridine]-3'-[S-(β-(Benzoylmercapto)ethyl)Pyrrolidino Thiophosphoroamidite]

5'-DMT-2'-O-MOE-U-3'-PS-Phosphoramidite

Description: 5'-DMT-2'-O-MOE-U-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It consists of a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methoxyethyl (MOE) modification on the ribose sugar, and a uridine base. Additionally, it contains a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and enhances stability, making it suitable for various applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.

CAT: BRP-00413

CAS: 2360826-71-5

MF: C46H52N3O10PS2

MF: 902.03

Purity: ≥90% by HPLC

Appearance: White to yellow powder

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InChIKey: SDTFEZZYTOLLHY-SRYSXPHVSA-N

CanonicalSMILES: O=C(SCCSP(OC1C(OC(N2C=CC(=O)NC2=O)C1OCCOC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N6CCCC6)C=7C=CC=CC7

IUPAC Name: S-(2-(((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate

InChI: InChI=1S/C46H52N3O10PS2/c1-53-28-29-56-42-41(59-60(48-25-10-11-26-48)62-31-30-61-44(51)33-12-6-4-7-13-33)39(58-43(42)49-27-24-40(50)47-45(49)52)32-57-46(34-14-8-5-9-15-34,35-16-20-37(54-2)21-17-35)36-18-22-38(55-3)23-19-36/h4-9,12-24,27,39,41-43H,10-11,25-26,28-32H2,1-3H3,(H,47,50,52)/t39-,41-,42-,43-,60?/m1/s1

Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyluridine]-3'-[S-(β-(Benzoylmercapto)ethyl)Pyrrolidino Thiophosphoroamidite]

DMT-2'-OMe-N1-Me-Pseudouridine 3'-CE phosphoramidite

Description: DMT-2'-OMe-N1-Me-Pseudouridine 3'-CE phosphoramidite is a compound utilized in nucleic acid synthesis, particularly in RNA synthesis. It comprises various functional groups including DMT (4,4'-Dimethoxytrityl) for protection, 2'-OMe for 2'-O-methylation, N1-Me for N1-methylation, and 3'-CE for 3'-cyanoethyl protection, along with a phosphoramidite moiety for incorporation into nucleotide chains.

CAT: BRP-00426

MF: C41H51N4O9P

MF: 744.85

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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InChIKey: GVNBVKSXXSEBDA-QKBNJDQWSA-N

IUPAC Name: (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxy-5-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C41H51N4O9P/c1-27(2)45(28(3)4)55(52-24-12-23-42)54-37-35(53-36(38(37)50-8)34-25-44(5)40(47)43-39(34)46)26-51-41(29-13-10-9-11-14-29,30-15-19-32(48-6)20-16-30)31-17-21-33(49-7)22-18-31/h9-11,13-22,25,27-28,35-38H,12,24,26H2,1-8H3,(H,43,46,47)/t35-,36+,37-,38+,55?/m1/s1

Synonyms: 5'-DMT-2'-O-Me-N1-Me-PseudoUridine-CE-Phosphoramidite; N1-Methyl-2'-O-Methyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; DMT-2'-OMe-N1-Me-Pseudouridine

3'-DMT-2'-OMe-A(Bz)-CE Reverse

Description: 3'-DMT-2'-OMe-A(Bz)-CE Reverse is a specialized nucleotide compound used in oligonucleotide synthesis. It comprises a 2'-O-methyl modification and a 3'-DMT protecting group to ensure stability during synthesis. Additionally, the adenosine base is modified with a benzoyl (Bz) group. The 5'-CED phosphoramidite functionality allows for controlled addition to oligonucleotide chains, offering precision in molecular biology research for customized oligonucleotide design and synthesis.

CAT: BRP-00427

CAS: 1309448-27-8

MF: C48H54N7O8P

MF: 887.96

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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InChIKey: ZTDLWOHDFXTWBU-PSVHYZMASA-N

CanonicalSMILES: N#CCCOP(OCC1OC(N2C=NC=3C(=NC=NC32)NC(=O)C=4C=CC=CC4)C(OC)C1OC(C=5C=CC=CC5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)N(C(C)C)C(C)C

IUPAC Name: ((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-methoxytetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C48H54N7O8P/c1-32(2)55(33(3)4)64(60-28-14-27-49)61-29-40-42(43(59-7)47(62-40)54-31-52-41-44(50-30-51-45(41)54)53-46(56)34-15-10-8-11-16-34)63-48(35-17-12-9-13-18-35,36-19-23-38(57-5)24-20-36)37-21-25-39(58-6)26-22-37/h8-13,15-26,30-33,40,42-43,47H,14,28-29H2,1-7H3,(H,50,51,53,56)/t40-,42-,43-,47-,64?/m1/s1

Synonyms: Adenosine, N-benzoyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 3'-O-DMTr-2'-O-Me-A(Bz)-5'-CE-Phosphoramidite; 2'-O-Methyl-3'-DMT Adenosine (n-bz) 5'-CED phosphoramidite

3'-DMT-2'-OMe-G(iBu)-CE Reverse

Description: 3'-DMT-2'-OMe-G(iBu)-CE Reverse is a specialized nucleotide compound used in oligonucleotide synthesis. It consists of a 2'-O-methyl modification and a 3'-DMT protecting group to ensure stability during synthesis. Additionally, the guanosine base is modified with an isobutyryl (ibu) group. The 5'-CED phosphoramidite functionality allows for controlled addition to oligonucleotide chains, providing precision in molecular biology research for tailored oligonucleotide design and synthesis.

CAT: BRP-00428

CAS: 2721427-31-0

MF: C45H56N7O9P

MF: 869.96

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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InChIKey: ZRRIKKNCSIFYAP-MLLDKZSOSA-N

CanonicalSMILES: N#CCCOP(OCC1OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C(OC)C1OC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C

IUPAC Name: ((2R,3R,4R,5R)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9)38(36(60-43)26-59-62(58-25-13-24-46)52(29(3)4)30(5)6)61-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/m1/s1

Synonyms: 3'-O-DMTr-2'-O-Me-G(iBu)-5'-CE-Phosphoramidite; 2'-O-Methyl-3'-DMT Guanosine (n-ibu) 5'-CED phosphoramidite

3'-DMT-2'-OMe-C(Ac)-CE Reverse

Description: 3'-DMT-2'-OMe-C(Ac)-CE Reverse is a specialized nucleotide compound used in oligonucleotide synthesis. It features a 2'-O-methyl modification and a 3'-DMT protecting group to ensure stability during synthesis. Additionally, the cytidine base is modified with an acetyl (N-Ac) group. The 5'-CED phosphoramidite functionality enables controlled addition to oligonucleotide chains, providing precision in molecular biology research for customized oligonucleotide design and synthesis.

CAT: BRP-00429

MF: C42H52N5O9P

MF: 801.88

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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InChIKey: ZAQGXRDUFSXSGR-UAQIPLLRSA-N

IUPAC Name: ((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-methoxytetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C42H52N5O9P/c1-28(2)47(29(3)4)57(53-26-12-24-43)54-27-36-38(39(52-8)40(55-36)46-25-23-37(44-30(5)48)45-41(46)49)56-42(31-13-10-9-11-14-31,32-15-19-34(50-6)20-16-32)33-17-21-35(51-7)22-18-33/h9-11,13-23,25,28-29,36,38-40H,12,26-27H2,1-8H3,(H,44,45,48,49)/t36-,38-,39-,40-,57?/m1/s1

Synonyms: 3'-O-DMTr-2'-O-Me-C(Ac)-5'-CE-Phosphoramidite; 2'-O-Methyl-3'-DMT Cytidine (N-Ac) 5'-CED phosphoramidite

3'-O-DMTr-2'-O-Me-rU-5'-CE-Phosphoramidite

Description: 3'-O-DMTr-2'-O-Me-rU-5'-CE-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It contains a 3'-dimethoxytrityl (DMTr) protecting group on the 3' hydroxyl, a methyl (Me) modification at the 2' position of the ribose sugar with uracil (U) as the base, and a 5'-cyanoethyl (CE) phosphoramidite functionality for controlled addition during synthesis. This compound facilitates stable and precise synthesis of customized oligonucleotides for molecular biology research applications.

CAT: BRP-00430

CAS: 2721427-32-1

MF: C40H49N4O9P

MF: 760.82

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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InChIKey: ATKRAEVWEXDALJ-XKZJCBTISA-N

CanonicalSMILES: N#CCCOP(OCC1OC(N2C=CC(=O)NC2=O)C(OC)C1OC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C

IUPAC Name: ((2R,3R,4R,5R)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C40H49N4O9P/c1-27(2)44(28(3)4)54(50-25-11-23-41)51-26-34-36(37(49-7)38(52-34)43-24-22-35(45)42-39(43)46)53-40(29-12-9-8-10-13-29,30-14-18-32(47-5)19-15-30)31-16-20-33(48-6)21-17-31/h8-10,12-22,24,27-28,34,36-38H,11,25-26H2,1-7H3,(H,42,45,46)/t34-,36-,37-,38-,54?/m1/s1

Synonyms: 3'-DMT-2'-OMe-U-CE Reverse; 2'-O-Methyl-3'-DMT Uridine 5'-CED phosphoramidite

UNA-C(Ac)-CE Phosphoramidite

Description: UNA-C(Ac)-CE Phosphoramidite is a compound employed in the chemical synthesis of nucleic acids, specifically in RNA synthesis. It features a UNA (Unlocked Nucleic Acid) modification, denoted by "UNA," which alters the structure and properties of the nucleotide. The "C(Ac)" indicates the nucleotide base cytosine (C) with an acetyl (Ac) group attached, potentially impacting base pairing and stability. Additionally, "CE" denotes cyanoethyl, a protecting group for the phosphate moiety, and "Phosphoramidite" refers to the reactive form of the nucleotide used in automated oligonucleotide synthesis. This compound facilitates controlled addition of modified nucleotides during RNA synthesis for various research and biotechnological applications.

CAT: BRP-00431

CAS: 1120329-56-7

MF: C48H56N5O10P

MF: 893.96

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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InChIKey: UMUWXRLDMCRCFS-GXOVKUNTSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)OC(COC(=O)C4=CC=CC=C4)N5C=CC(=NC5=O)NC(=O)C

IUPAC Name: [(2R)-2-(4-acetamido-2-oxopyrimidin-1-yl)-2-[(2R)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]oxyethyl] benzoate

InChI: InChI=1S/C48H56N5O10P/c1-34(2)53(35(3)4)64(61-30-14-28-49)62-32-43(63-45(33-59-46(55)37-15-10-8-11-16-37)52-29-27-44(50-36(5)54)51-47(52)56)31-60-48(38-17-12-9-13-18-38,39-19-23-41(57-6)24-20-39)40-21-25-42(58-7)26-22-40/h8-13,15-27,29,34-35,43,45H,14,30-33H2,1-7H3,(H,50,51,54,56)/t43-,45-,64?/m1/s1

Synonyms: (2R)-2-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-2-(((2R)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)propan-2-yl)oxy)ethyl benzoate; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2R)-2-[(1R)-1-[4-(acetylamino)-2-oxo-1(2H)-pyrimidinyl]-2-(benzoyloxy)ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester; (2R)-2-[(1R)-1-[4-(Acetylamino)-2-oxo-1(2H)-pyrimidinyl]-2-(benzoyloxy)ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite

UNA-U-CE Phosphoramidite

Description: UNA-U-CE Phosphoramidite is a compound utilized in nucleic acid synthesis, particularly in RNA synthesis. It consists of UNA (Unlocked Nucleic Acid), denoted by "UNA," which modifies the nucleotide structure and properties. The "U" signifies uridine as the base, and "CE" indicates cyanoethyl, a protecting group for the phosphate moiety. "Phosphoramidite" refers to the reactive form of the nucleotide used in automated oligonucleotide synthesis. This compound enables controlled addition of modified uridine nucleotides during RNA synthesis for various research and biotechnological applications.

CAT: BRP-00432

CAS: 1120329-48-7

MF: C46H53N4O10P

MF: 852.91

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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InChIKey: MHRGEJFLFYZLJI-LZOZAVILSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)OC(COC(=O)C4=CC=CC=C4)N5C=CC(=O)NC5=O

IUPAC Name: [(2R)-2-[(2R)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]oxy-2-(2,4-dioxopyrimidin-1-yl)ethyl] benzoate

InChI: InChI=1S/C46H53N4O10P/c1-33(2)50(34(3)4)61(58-29-13-27-47)59-31-41(60-43(49-28-26-42(51)48-45(49)53)32-56-44(52)35-14-9-7-10-15-35)30-57-46(36-16-11-8-12-17-36,37-18-22-39(54-5)23-19-37)38-20-24-40(55-6)25-21-38/h7-12,14-26,28,33-34,41,43H,13,29-32H2,1-6H3,(H,48,51,53)/t41-,43-,61?/m1/s1

Synonyms: 5'-(4,4'-dimethoxytrityl)-2'-benzoyl-2',3'-seco-uridine-3'-cyanoethyl Phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2R)-2-[(1R)-2-(benzoyloxy)-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester; 5'-DMTr-2'-Bz-3'-O-CEP-UNA-U; 5'-(4,4'-dimethoxytrityl)-2'-benzoyl-2',3'-seco-uridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)] Phosphoramidite; (2R)-2-[(1R)-2-(Benzoyloxy)-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite

Morpholino G(PhAc) subunit

Description: The Morpholino G(PhAc) subunit is a component used in the synthesis of morpholino oligomers, synthetic analogs of nucleic acids. It features a morpholine ring structure as the backbone, with a guanine base modified by a phenylacetyl group (PhAc). This modification enhances the binding affinity of the oligomers to complementary RNA or DNA targets. The Morpholino G(PhAc) subunit is utilized in molecular biology and biotechnology for applications such as gene knockdown experiments, antisense therapy, and the study of gene function.

CAT: BRP-00433

CAS: 1044241-74-8

MF: C39H39ClN7O5P

MF: 752.20

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Density: 1.37±0.1 g/cm3

InChIKey: NURVOJDGJURYKG-BFXPVMCSSA-N

CanonicalSMILES: O=C1N=C(NC(=O)CC=2C=CC=CC2)NC3=C1N=CN3C4OC(COP(=O)(Cl)N(C)C)CN(C4)C(C=5C=CC=CC5)(C=6C=CC=CC6)C=7C=CC=CC7

IUPAC Name: ((2S,6R)-6-(6-oxo-2-(2-phenylacetamido)-1,6-dihydro-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate

InChI: InChI=1S/C39H39ClN7O5P/c1-45(2)53(40,50)51-26-32-24-46(39(29-17-9-4-10-18-29,30-19-11-5-12-20-30)31-21-13-6-14-22-31)25-34(52-32)47-27-41-35-36(47)43-38(44-37(35)49)42-33(48)23-28-15-7-3-8-16-28/h3-22,27,32,34H,23-26H2,1-2H3,(H2,42,43,44,48,49)/t32-,34+,53?/m0/s1

Synonyms: Phosphoramidochloridic acid, N,N-dimethyl-, [(2S,6R)-6-[1,6-dihydro-6-oxo-2-[(2-phenylacetyl)amino]-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester; [(2S,6R)-6-[1,6-Dihydro-6-oxo-2-[(2-phenylacetyl)amino]-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl N,N-dimethylphosphoramidochloridate; (2S,6R)-6-(6-oxo-2-(2-phenylacetamido)-1H-purin-9(6H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate

VIC phosphoramidite, 6-isomer

Description: VIC is an asymmetrical xanthene dye used for the design of qPCR probes. VIC phosphoramidite, 6-isomer allows to introduce the label onto 5'-terminus of the oligonucleotide.

CAT: BRP-00472

CAS: 1414265-81-8

MF: C52H59Cl3N3O10P

MF: 1023.37

Purity: ≥95%

Appearance: White to Off-white Solid

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InChIKey: WNXGKJMDPRPEFO-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)C1=CC(=C2C(=C1Cl)C3(C4=CC(=C(C=C4OC5=C3C=C(C(=C5)OC(=O)C(C)(C)C)C6=CC=CC=C6)OC(=O)C(C)(C)C)Cl)OC2=O)Cl)OCCC#N

IUPAC Name: [4,7,7'-trichloro-6-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxo-2'-phenylspiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate

InChI: InChI=1S/C52H59Cl3N3O10P/c1-30(2)58(31(3)4)69(64-24-18-21-56)63-23-17-12-11-16-22-57-46(59)34-26-38(54)43-44(45(34)55)52(68-47(43)60)35-25-33(32-19-14-13-15-20-32)39(66-48(61)50(5,6)7)28-40(35)65-41-29-42(37(53)27-36(41)52)67-49(62)51(8,9)10/h13-15,19-20,25-31H,11-12,16-18,22-24H2,1-10H3,(H,57,59)

Synonyms: 6-VIC Phosphoramidite