Inquiry Basket
2'-Modified Phosphoramidites
(529/529) 2'-Phosphoramidites
(27/27) 3'-Modified Phosphoramidites
(201/201) 5'-Modified Phosphoramidites
(30/30) Arabino Phosphoramidites
(23/23) Base Protected Phosphoramidites (418/418) Dye Phosphoramidites
(53/53) Label Phosphoramidites
(82/82) Linker Phosphoramidites
(85/85) Other Phosphoramidites
(97/97) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(25/25) Spacer Phosphoramidites
(24/24)
(529/529) 2'-Phosphoramidites
(27/27) 3'-Modified Phosphoramidites
(201/201) 5'-Modified Phosphoramidites
(30/30) Arabino Phosphoramidites
(23/23) Base Protected Phosphoramidites (418/418) Dye Phosphoramidites
(53/53) Label Phosphoramidites
(82/82) Linker Phosphoramidites
(85/85) Other Phosphoramidites
(97/97) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(25/25) Spacer Phosphoramidites
(24/24)
Backbone
Modification
Base Type
Filtered by
Clear All
DMT-2'-O-TBDMS-G(dmf)-CE Phosphoramidite
Description: DMT-2'-O-TBDMS-G(dmf)-CE Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group on the 3' hydroxyl, a tert-butyldimethylsilyl (TBDMS) protecting group on the 2' hydroxyl, and a guanine base modified with a dimethylformamide (dmf) group. Additionally, it contains a 5'-cyanoethyl (CE) phosphoramidite functionality for controlled addition during synthesis. This compound enables stable and precise synthesis of oligonucleotides for various molecular biology research applications, including gene silencing, antisense therapy, and diagnostics.
CAT: BRP-00402
CAS: 149559-87-5
Molecular Formula: C49H67N8O8PSi
Molecular Weight: 955.18
Purity: ≥95%
Appearance: White to light yellow powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: RQXRLANMGPTUJP-UTESLAMRSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=NC3=C2N=C(NC3=O)N=CN(C)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC
IUPAC Name: N'-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-N,N-dimethylmethanimidamide
InChI: InChI=1S/C49H67N8O8PSi/c1-33(2)57(34(3)4)66(62-29-17-28-50)64-42-40(30-61-49(35-18-15-14-16-19-35,36-20-24-38(59-10)25-21-36)37-22-26-39(60-11)27-23-37)63-46(43(42)65-67(12,13)48(5,6)7)56-32-51-41-44(56)53-47(54-45(41)58)52-31-55(8)9/h14-16,18-27,31-34,40,42-43,46H,17,29-30H2,1-13H3,(H,53,54,58)/t40-,42-,43-,46-,66?/m1/s1
Synonyms: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N2-Dimethylformamidine-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-guanosine-3'-cyanoethyl Phosphoramidite; 5'-O-DMT-2'-O-TBDMS-N2-DMF-Guanosine 3'-CE phosphoramidite; rG (dmf) CE-Phosphoramidite
-3'-ps.gif)
5'-DMT-2'-OMe-A(Bz)-3'-PS-Phosphoramidite
Description: 5'-DMT-2'-OMe-A(Bz)-3'-PS-Phosphoramidite is a specialized nucleotide compound utilized in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and an adenine base modified with a benzoyl (Bz) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite enables controlled addition during synthesis and offers enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It finds applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.
CAT: BRP-00403
Molecular Formula: C52H53N6O8PS2
Molecular Weight: 985.12
Purity: ≥98% by HPLC
Appearance: White to off-white powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: CLDYJLPUISOESS-LTMMGAFGSA-N
CanonicalSMILES: COC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N8CCCC8)SCCSC(=O)C9=CC=CC=C9
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C52H53N6O8PS2/c1-61-41-25-21-39(22-26-41)52(38-19-11-6-12-20-38,40-23-27-42(62-2)28-24-40)64-33-43-45(66-67(57-29-13-14-30-57)69-32-31-68-51(60)37-17-9-5-10-18-37)46(63-3)50(65-43)58-35-55-44-47(53-34-54-48(44)58)56-49(59)36-15-7-4-8-16-36/h4-12,15-28,34-35,43,45-46,50H,13-14,29-33H2,1-3H3,(H,53,54,56,59)/t43-,45-,46-,50-,67?/m1/s1
Synonyms: S-(2-(((((2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphino)thio)ethyl) benzothioate; DMT-2'-OMe-A(Bz)-3'-PS; [N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-adenosine]-3'-[S-(β-(Benzoylmercapto)ethyl) Pyrrolidino Thiophosphoroamidite]; 2'-OMe-A-Thiophosphoramidite; 5'-Dimethoxytrityl-N-benzoyl-Adenosine, 2'-O-methyl, 3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite
-3'-ps-phosphoramidite.gif)
5'-DMT-2'-OMe-G(iBu)-3'-PS-Phosphoramidite
Description: 5'-DMT-2'-OMe-G(iBu)-3'-PS-Phosphoramidite is a specialized nucleotide compound employed in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and a guanine base modified with an isobutyl (iBu) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite enables controlled addition during synthesis and offers enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It finds applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.
CAT: BRP-00404
Molecular Formula: C49H55N6O9PS2
Molecular Weight: 967.11
Purity: ≥90% by HPLC
Appearance: White to yellow powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: HZMNPGZRUUSWOU-VKFKYRIUSA-N
CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N7CCCC7)SCCSC(=O)C8=CC=CC=C8)OC
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxy-5-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]oxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C49H55N6O9PS2/c1-32(2)44(56)52-48-51-43-40(45(57)53-48)50-31-55(43)46-42(61-5)41(64-65(54-26-12-13-27-54)67-29-28-66-47(58)33-14-8-6-9-15-33)39(63-46)30-62-49(34-16-10-7-11-17-34,35-18-22-37(59-3)23-19-35)36-20-24-38(60-4)25-21-36/h6-11,14-25,31-32,39,41-42,46H,12-13,26-30H2,1-5H3,(H2,51,52,53,56,57)/t39-,41-,42-,46-,65?/m1/s1
Synonyms: DMT-2'-OMe-G(iBu)-3'-PS; [N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-guanosine]-3'-[S-(β-(Benzoylmercapto)ethyl)pyrrolidino Thiophosphoroamidite]; S-(2-(((((2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1H-purin-9(6H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphino)thio)ethyl) benzothioate; 2'-OMe-G-Thiophosphoramidite; 5'-Dimethoxytrityl-N-isobutyryl-Guanosine, 2'-O-methyl,3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite
5'-DMT-2'-O-MOE-G(iBu)-3'-PS-Phosphoramidite
Description: 5'-DMT-2'-O-MOE-G(iBu)-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methoxyethyl (MOE) modification on the ribose sugar, and a guanine base modified with an isobutyl (iBu) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and provides enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It is utilized in various molecular biology research applications, including gene synthesis, RNA interference, and nucleic acid probe development.
CAT: BRP-00405
CAS: 2360826-78-2
Molecular Formula: C51H59N6O10PS2
Molecular Weight: 1011.16
Purity: ≥90% by HPLC
Appearance: White to yellow powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: HDXVTGDRJQVYMX-MGIZDRFQSA-N
CanonicalSMILES: O=C1N=C(NC(=O)C(C)C)NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(OP(SCCSC(=O)C=7C=CC=CC7)N8CCCC8)C3OCCOC
IUPAC Name: S-(2-(((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate
InChI: InChI=1S/C51H59N6O10PS2/c1-34(2)46(58)54-50-53-45-42(47(59)55-50)52-33-57(45)48-44(64-29-28-61-3)43(67-68(56-26-12-13-27-56)70-31-30-69-49(60)35-14-8-6-9-15-35)41(66-48)32-65-51(36-16-10-7-11-17-36,37-18-22-39(62-4)23-19-37)38-20-24-40(63-5)25-21-38/h6-11,14-25,33-34,41,43-44,48H,12-13,26-32H2,1-5H3,(H2,53,54,55,58,59)/t41-,43-,44-,48-,68?/m1/s1
Synonyms: [N2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-guanosine]-3'-[S-(β-(Benzoylmercapto)ethyl) Pyrrolidino Thiophosphoroamidite]
5'-DMT-2'-O-MOE-A(Bz)-3'-PS-Phosphoramidite
Description: 5'-DMT-2'-O-MOE-A(Bz)-3'-PS-Phosphoramidite is a specialized nucleotide compound utilized in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methoxyethyl (MOE) modification on the ribose sugar, and an adenine base modified with a benzoyl (Bz) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite enables controlled addition during synthesis and offers enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It finds applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.
CAT: BRP-00406
CAS: 2360826-72-6
Molecular Formula: C54H57N6O9PS2
Molecular Weight: 1029.18
Purity: ≥90% by HPLC
Appearance: White to yellow powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: OKYFNXWXBWXJHI-QRWWDSLFSA-N
CanonicalSMILES: O=C(SCCSP(OC1C(OC(N2C=NC=3C(=NC=NC32)NC(=O)C=4C=CC=CC4)C1OCCOC)COC(C=5C=CC=CC5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)N8CCCC8)C=9C=CC=CC9
IUPAC Name: S-(2-(((((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate
InChI: InChI=1S/C54H57N6O9PS2/c1-63-31-32-66-48-47(69-70(59-29-13-14-30-59)72-34-33-71-53(62)39-17-9-5-10-18-39)45(68-52(48)60-37-57-46-49(55-36-56-50(46)60)58-51(61)38-15-7-4-8-16-38)35-67-54(40-19-11-6-12-20-40,41-21-25-43(64-2)26-22-41)42-23-27-44(65-3)28-24-42/h4-12,15-28,36-37,45,47-48,52H,13-14,29-35H2,1-3H3,(H,55,56,58,61)/t45-,47-,48-,52-,70?/m1/s1
Synonyms: [N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine]-3'-[S-(β-(Benzoylmercapto)ethyl) Pyrrolidino Thiophosphoroamidite]
5'-DMT-2'-O-MOE-5-Me-C(Bz)-3'-PS-Phosphoramidite
Description: 5'-DMT-2'-O-MOE-5-Me-C(Bz)-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methoxyethyl (MOE) modification on the ribose sugar, and a 5-methylcytosine base modified with a benzoyl (Bz) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite enables controlled addition during synthesis and provides enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It is utilized in various molecular biology research applications, including gene synthesis, RNA interference, and nucleic acid probe development.
CAT: BRP-00407
CAS: 2360826-74-8
Molecular Formula: C54H59N4O10PS2
Molecular Weight: 1019.18
Purity: ≥90% by HPLC
Appearance: White to yellow powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: JHTAVHWNDBSHFT-GDWCHFCQSA-N
CanonicalSMILES: O=C1N=C(NC(=O)C=2C=CC=CC2)C(=CN1C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(OP(SCCSC(=O)C=7C=CC=CC7)N8CCCC8)C3OCCOC)C
IUPAC Name: S-(2-(((((2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate
InChI: InChI=1S/C54H59N4O10PS2/c1-38-36-58(53(61)56-49(38)55-50(59)39-16-8-5-9-17-39)51-48(65-33-32-62-2)47(68-69(57-30-14-15-31-57)71-35-34-70-52(60)40-18-10-6-11-19-40)46(67-51)37-66-54(41-20-12-7-13-21-41,42-22-26-44(63-3)27-23-42)43-24-28-45(64-4)29-25-43/h5-13,16-29,36,46-48,51H,14-15,30-35,37H2,1-4H3,(H,55,56,59,61)/t46-,47-,48-,51-,69?/m1/s1
Synonyms: [N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-5-methyl-cytidine]-3'-[S-(β-(Benzoylmercapto)ethyl) Pyrrolidino Thiophosphoroamidite]
-3'-ps-phosphoramidite.gif)
5'-DMT-2'-OMe-5-Me-C(Bz)-3'-PS-Phosphoramidite
Description: 5'-DMT-2'-OMe-5-Me-C(Bz)-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It consists of a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and a 5-methylcytosine base modified with a benzoyl (Bz) group. Additionally, it features a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and enhances stability, making it suitable for applications such as gene synthesis, RNA interference, and nucleic acid probe development in molecular biology research.
CAT: BRP-00408
Molecular Formula: C52H55N4O9PS2
Molecular Weight: 975.12
Purity: ≥90% by HPLC
Appearance: White to yellow powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: DOVLPDMECIOKGA-BZPNBFHRSA-N
CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N7CCCC7)SCCSC(=O)C8=CC=CC=C8)OC
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-5-(4-benzamido-5-methyl-2-oxopyrimidin-1-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C52H55N4O9PS2/c1-36-34-56(51(59)54-47(36)53-48(57)37-16-8-5-9-17-37)49-46(62-4)45(65-66(55-30-14-15-31-55)68-33-32-67-50(58)38-18-10-6-11-19-38)44(64-49)35-63-52(39-20-12-7-13-21-39,40-22-26-42(60-2)27-23-40)41-24-28-43(61-3)29-25-41/h5-13,16-29,34,44-46,49H,14-15,30-33,35H2,1-4H3,(H,53,54,57,59)/t44-,45-,46-,49-,66?/m1/s1
Synonyms: [N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyl-cytidine]-3'-[S-(β-(Benzoylmercapto)ethyl) Pyrrolidino Thiophosphoroamidite]; S-(2-(((((2R,3R,4R,5R)-5-(4-Benzamido-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphino)thio)ethyl) benzothioate
-3'-ps-phosphoramidite.gif)
5'-DMT-2'-OMe-C(Ac)-3'-PS-Phosphoramidite
Description: 5'-DMT-2'-OMe-C(Ac)-3'-PS-Phosphoramidite is a specialized nucleotide compound utilized in oligonucleotide synthesis. It features a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and a cytidine base modified with an acetyl (Ac) group. Additionally, it incorporates a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite enables controlled addition during synthesis and provides enhanced stability and resistance to nuclease degradation in oligonucleotide sequences. It is employed in various molecular biology research applications, including gene synthesis, RNA interference, and nucleic acid probe development.
CAT: BRP-00409
Molecular Formula: C46H51N4O9PS2
Molecular Weight: 899.03
Purity: ≥90% by HPLC
Appearance: White to yellow powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: CNCXGATYHORASL-SRYSXPHVSA-N
CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7)OC
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C46H51N4O9PS2/c1-32(51)47-40-25-28-50(45(53)48-40)43-42(56-4)41(59-60(49-26-11-12-27-49)62-30-29-61-44(52)33-13-7-5-8-14-33)39(58-43)31-57-46(34-15-9-6-10-16-34,35-17-21-37(54-2)22-18-35)36-19-23-38(55-3)24-20-36/h5-10,13-25,28,39,41-43H,11-12,26-27,29-31H2,1-4H3,(H,47,48,51,53)/t39-,41-,42-,43-,60?/m1/s1
Synonyms: DMT-2'-OMe-C(Ac)-3'-PS; [N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyl-cytidine]-3'-[S-(β-(Benzoylmercapto)ethyl) Pyrrolidino Thiophosphoroamidite]; S-(2-(((((2R,3R,4R,5R)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphino)thio)ethyl) benzothioate; 2'-OMe-C-Thiophosphoramidite; 5'-Dimethoxytrityl-N-acetyl-Cytidine, 2'-O-methyl,3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite
5'-DMT-2'-OMe-U-3'-PS-Phosphoramidite
Description: 5'-DMT-2'-OMe-U-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It comprises a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and a uridine base. Additionally, it contains a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and enhances stability, making it suitable for various applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.
CAT: BRP-00410
Molecular Formula: C44H48N3O9PS2
Molecular Weight: 857.97
Purity: ≥90% by HPLC
Appearance: White to yellow powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: WOJBALAHZBVIKR-QBLJBMGASA-N
CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C44H48N3O9PS2/c1-51-35-20-16-33(17-21-35)44(32-14-8-5-9-15-32,34-18-22-36(52-2)23-19-34)54-30-37-39(40(53-3)41(55-37)47-27-24-38(48)45-43(47)50)56-57(46-25-10-11-26-46)59-29-28-58-42(49)31-12-6-4-7-13-31/h4-9,12-24,27,37,39-41H,10-11,25-26,28-30H2,1-3H3,(H,45,48,50)/t37-,39-,40-,41-,57?/m1/s1
Synonyms: DMT-2'-OMe-U-3'-PS; [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-uridine]-3'-[S-(β-(Benzoylmercapto)ethyl)Pyrrolidino Thiophosphoroamidite]; S-(2-(((((2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphino)thio)ethyl) benzothioate; 2'-OMe-U-Thiophosphoramidite; 5'-Dimethoxytrityl-Uridine, 2'-O-methyl, 3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite
5'-DMT-2'-OMe-5-Me-U-3'-PS-Phosphoramidite
Description: 5'-DMT-2'-OMe-5-Me-U-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It consists of a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methyl modification on the ribose sugar, and a 5-methyluridine base. Additionally, it features a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and enhances stability, making it suitable for various applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.
CAT: BRP-00411
Molecular Formula: C45H50N3O9PS2
Molecular Weight: 872.00
Purity: ≥90% by HPLC
Appearance: White to yellow powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: IWVGGTNZQUQJEA-MWUWPPOZSA-N
CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N6CCCC6)SCCSC(=O)C7=CC=CC=C7)OC
IUPAC Name: S-[2-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-methoxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-pyrrolidin-1-ylphosphanyl]sulfanylethyl] benzenecarbothioate
InChI: InChI=1S/C45H50N3O9PS2/c1-31-29-48(44(51)46-41(31)49)42-40(54-4)39(57-58(47-25-11-12-26-47)60-28-27-59-43(50)32-13-7-5-8-14-32)38(56-42)30-55-45(33-15-9-6-10-16-33,34-17-21-36(52-2)22-18-34)35-19-23-37(53-3)24-20-35/h5-10,13-24,29,38-40,42H,11-12,25-28,30H2,1-4H3,(H,46,49,51)/t38-,39-,40-,42-,58?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyl-uridine]-3'-[S-(β-(Benzoylmercapto)ethyl)Pyrrolidino Thiophosphoroamidite]; S-(2-(((((2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphino)thio)ethyl) benzothioate
5'-DMT-2'-O-MOE-5-Me-U-3'-PS-Phosphoramidite
Description: 5'-DMT-2'-O-MOE-5-Me-U-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It comprises a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methoxyethyl (MOE) modification on the ribose sugar, and a 5-methyluridine base. Additionally, it contains a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and enhances stability, making it suitable for various applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.
CAT: BRP-00412
CAS: 2360826-70-4
Molecular Formula: C47H54N3O10PS2
Molecular Weight: 916.05
Purity: ≥90% by HPLC
Appearance: White to yellow powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: VCDBYBSSVSRJPT-OMRXSTERSA-N
CanonicalSMILES: O=C(SCCSP(OC1C(OC(N2C=C(C(=O)NC2=O)C)C1OCCOC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N6CCCC6)C=7C=CC=CC7
IUPAC Name: S-(2-(((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate
InChI: InChI=1S/C47H54N3O10PS2/c1-33-31-50(46(53)48-43(33)51)44-42(57-28-27-54-2)41(60-61(49-25-11-12-26-49)63-30-29-62-45(52)34-13-7-5-8-14-34)40(59-44)32-58-47(35-15-9-6-10-16-35,36-17-21-38(55-3)22-18-36)37-19-23-39(56-4)24-20-37/h5-10,13-24,31,40-42,44H,11-12,25-30,32H2,1-4H3,(H,48,51,53)/t40-,41-,42-,44-,61?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-5-methyl-uridine]-3'-[S-(β-(Benzoylmercapto)ethyl)Pyrrolidino Thiophosphoroamidite]
5'-DMT-2'-O-MOE-U-3'-PS-Phosphoramidite
Description: 5'-DMT-2'-O-MOE-U-3'-PS-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It consists of a dimethoxytrityl (DMT) protecting group at the 5' position, a 2'-O-methoxyethyl (MOE) modification on the ribose sugar, and a uridine base. Additionally, it contains a phosphorothioate (PS) linkage at the 3' position. This phosphoramidite facilitates controlled addition during synthesis and enhances stability, making it suitable for various applications in molecular biology research, including gene synthesis, RNA interference, and nucleic acid probe development.
CAT: BRP-00413
CAS: 2360826-71-5
Molecular Formula: C46H52N3O10PS2
Molecular Weight: 902.03
Purity: ≥90% by HPLC
Appearance: White to yellow powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: SDTFEZZYTOLLHY-SRYSXPHVSA-N
CanonicalSMILES: O=C(SCCSP(OC1C(OC(N2C=CC(=O)NC2=O)C1OCCOC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N6CCCC6)C=7C=CC=CC7
IUPAC Name: S-(2-(((((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate
InChI: InChI=1S/C46H52N3O10PS2/c1-53-28-29-56-42-41(59-60(48-25-10-11-26-48)62-31-30-61-44(51)33-12-6-4-7-13-33)39(58-43(42)49-27-24-40(50)47-45(49)52)32-57-46(34-14-8-5-9-15-34,35-16-20-37(54-2)21-17-35)36-18-22-38(55-3)23-19-36/h4-9,12-24,27,39,41-43H,10-11,25-26,28-32H2,1-3H3,(H,47,50,52)/t39-,41-,42-,43-,60?/m1/s1
Synonyms: [5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyluridine]-3'-[S-(β-(Benzoylmercapto)ethyl)Pyrrolidino Thiophosphoroamidite]
DMT-2'-OMe-N1-Me-Pseudouridine 3'-CE phosphoramidite
Description: DMT-2'-OMe-N1-Me-Pseudouridine 3'-CE phosphoramidite is a compound utilized in nucleic acid synthesis, particularly in RNA synthesis. It comprises various functional groups including DMT (4,4'-Dimethoxytrityl) for protection, 2'-OMe for 2'-O-methylation, N1-Me for N1-methylation, and 3'-CE for 3'-cyanoethyl protection, along with a phosphoramidite moiety for incorporation into nucleotide chains.
CAT: BRP-00426
Molecular Formula: C41H51N4O9P
Molecular Weight: 744.85
Purity: ≥98% by HPLC
Appearance: White to off-white powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: GVNBVKSXXSEBDA-QKBNJDQWSA-N
IUPAC Name: (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxy-5-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C41H51N4O9P/c1-27(2)45(28(3)4)55(52-24-12-23-42)54-37-35(53-36(38(37)50-8)34-25-44(5)40(47)43-39(34)46)26-51-41(29-13-10-9-11-14-29,30-15-19-32(48-6)20-16-30)31-17-21-33(49-7)22-18-31/h9-11,13-22,25,27-28,35-38H,12,24,26H2,1-8H3,(H,43,46,47)/t35-,36+,37-,38+,55?/m1/s1
Synonyms: 5'-DMT-2'-O-Me-N1-Me-PseudoUridine-CE-Phosphoramidite; N1-Methyl-2'-O-Methyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; DMT-2'-OMe-N1-Me-Pseudouridine
3'-DMT-2'-OMe-A(Bz)-CE Reverse
Description: 3'-DMT-2'-OMe-A(Bz)-CE Reverse is a specialized nucleotide compound used in oligonucleotide synthesis. It comprises a 2'-O-methyl modification and a 3'-DMT protecting group to ensure stability during synthesis. Additionally, the adenosine base is modified with a benzoyl (Bz) group. The 5'-CED phosphoramidite functionality allows for controlled addition to oligonucleotide chains, offering precision in molecular biology research for customized oligonucleotide design and synthesis.
CAT: BRP-00427
CAS: 1309448-27-8
Molecular Formula: C48H54N7O8P
Molecular Weight: 887.96
Purity: ≥98% by HPLC
Appearance: White to off-white powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: ZTDLWOHDFXTWBU-PSVHYZMASA-N
CanonicalSMILES: N#CCCOP(OCC1OC(N2C=NC=3C(=NC=NC32)NC(=O)C=4C=CC=CC4)C(OC)C1OC(C=5C=CC=CC5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)N(C(C)C)C(C)C
IUPAC Name: ((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-methoxytetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C48H54N7O8P/c1-32(2)55(33(3)4)64(60-28-14-27-49)61-29-40-42(43(59-7)47(62-40)54-31-52-41-44(50-30-51-45(41)54)53-46(56)34-15-10-8-11-16-34)63-48(35-17-12-9-13-18-35,36-19-23-38(57-5)24-20-36)37-21-25-39(58-6)26-22-37/h8-13,15-26,30-33,40,42-43,47H,14,28-29H2,1-7H3,(H,50,51,53,56)/t40-,42-,43-,47-,64?/m1/s1
Synonyms: Adenosine, N-benzoyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 3'-O-DMTr-2'-O-Me-A(Bz)-5'-CE-Phosphoramidite; 2'-O-Methyl-3'-DMT Adenosine (n-bz) 5'-CED phosphoramidite
3'-DMT-2'-OMe-G(iBu)-CE Reverse
Description: 3'-DMT-2'-OMe-G(iBu)-CE Reverse is a specialized nucleotide compound used in oligonucleotide synthesis. It consists of a 2'-O-methyl modification and a 3'-DMT protecting group to ensure stability during synthesis. Additionally, the guanosine base is modified with an isobutyryl (ibu) group. The 5'-CED phosphoramidite functionality allows for controlled addition to oligonucleotide chains, providing precision in molecular biology research for tailored oligonucleotide design and synthesis.
CAT: BRP-00428
CAS: 2721427-31-0
Molecular Formula: C45H56N7O9P
Molecular Weight: 869.96
Purity: ≥98% by HPLC
Appearance: White to off-white powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: ZRRIKKNCSIFYAP-MLLDKZSOSA-N
CanonicalSMILES: N#CCCOP(OCC1OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C(OC)C1OC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: ((2R,3R,4R,5R)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9)38(36(60-43)26-59-62(58-25-13-24-46)52(29(3)4)30(5)6)61-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/m1/s1
Synonyms: 3'-O-DMTr-2'-O-Me-G(iBu)-5'-CE-Phosphoramidite; 2'-O-Methyl-3'-DMT Guanosine (n-ibu) 5'-CED phosphoramidite
-ce-reverse.gif)
3'-DMT-2'-OMe-C(Ac)-CE Reverse
Description: 3'-DMT-2'-OMe-C(Ac)-CE Reverse is a specialized nucleotide compound used in oligonucleotide synthesis. It features a 2'-O-methyl modification and a 3'-DMT protecting group to ensure stability during synthesis. Additionally, the cytidine base is modified with an acetyl (N-Ac) group. The 5'-CED phosphoramidite functionality enables controlled addition to oligonucleotide chains, providing precision in molecular biology research for customized oligonucleotide design and synthesis.
CAT: BRP-00429
Molecular Formula: C42H52N5O9P
Molecular Weight: 801.88
Purity: ≥98% by HPLC
Appearance: White to off-white powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: ZAQGXRDUFSXSGR-UAQIPLLRSA-N
IUPAC Name: ((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-4-methoxytetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C42H52N5O9P/c1-28(2)47(29(3)4)57(53-26-12-24-43)54-27-36-38(39(52-8)40(55-36)46-25-23-37(44-30(5)48)45-41(46)49)56-42(31-13-10-9-11-14-31,32-15-19-34(50-6)20-16-32)33-17-21-35(51-7)22-18-33/h9-11,13-23,25,28-29,36,38-40H,12,26-27H2,1-8H3,(H,44,45,48,49)/t36-,38-,39-,40-,57?/m1/s1
Synonyms: 3'-O-DMTr-2'-O-Me-C(Ac)-5'-CE-Phosphoramidite; 2'-O-Methyl-3'-DMT Cytidine (N-Ac) 5'-CED phosphoramidite
3'-O-DMTr-2'-O-Me-rU-5'-CE-Phosphoramidite
Description: 3'-O-DMTr-2'-O-Me-rU-5'-CE-Phosphoramidite is a specialized nucleotide used in oligonucleotide synthesis. It contains a 3'-dimethoxytrityl (DMTr) protecting group on the 3' hydroxyl, a methyl (Me) modification at the 2' position of the ribose sugar with uracil (U) as the base, and a 5'-cyanoethyl (CE) phosphoramidite functionality for controlled addition during synthesis. This compound facilitates stable and precise synthesis of customized oligonucleotides for molecular biology research applications.
CAT: BRP-00430
CAS: 2721427-32-1
Molecular Formula: C40H49N4O9P
Molecular Weight: 760.82
Purity: ≥98% by HPLC
Appearance: White to off-white powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: ATKRAEVWEXDALJ-XKZJCBTISA-N
CanonicalSMILES: N#CCCOP(OCC1OC(N2C=CC(=O)NC2=O)C(OC)C1OC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C
IUPAC Name: ((2R,3R,4R,5R)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-methoxytetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C40H49N4O9P/c1-27(2)44(28(3)4)54(50-25-11-23-41)51-26-34-36(37(49-7)38(52-34)43-24-22-35(45)42-39(43)46)53-40(29-12-9-8-10-13-29,30-14-18-32(47-5)19-15-30)31-16-20-33(48-6)21-17-31/h8-10,12-22,24,27-28,34,36-38H,11,25-26H2,1-7H3,(H,42,45,46)/t34-,36-,37-,38-,54?/m1/s1
Synonyms: 3'-DMT-2'-OMe-U-CE Reverse; 2'-O-Methyl-3'-DMT Uridine 5'-CED phosphoramidite
UNA-C(Ac)-CE Phosphoramidite
Description: UNA-C(Ac)-CE Phosphoramidite is a compound employed in the chemical synthesis of nucleic acids, specifically in RNA synthesis. It features a UNA (Unlocked Nucleic Acid) modification, denoted by "UNA," which alters the structure and properties of the nucleotide. The "C(Ac)" indicates the nucleotide base cytosine (C) with an acetyl (Ac) group attached, potentially impacting base pairing and stability. Additionally, "CE" denotes cyanoethyl, a protecting group for the phosphate moiety, and "Phosphoramidite" refers to the reactive form of the nucleotide used in automated oligonucleotide synthesis. This compound facilitates controlled addition of modified nucleotides during RNA synthesis for various research and biotechnological applications.
CAT: BRP-00431
CAS: 1120329-56-7
Molecular Formula: C48H56N5O10P
Molecular Weight: 893.96
Purity: ≥98% by HPLC
Appearance: White to off-white powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: UMUWXRLDMCRCFS-GXOVKUNTSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)OC(COC(=O)C4=CC=CC=C4)N5C=CC(=NC5=O)NC(=O)C
IUPAC Name: [(2R)-2-(4-acetamido-2-oxopyrimidin-1-yl)-2-[(2R)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]oxyethyl] benzoate
InChI: InChI=1S/C48H56N5O10P/c1-34(2)53(35(3)4)64(61-30-14-28-49)62-32-43(63-45(33-59-46(55)37-15-10-8-11-16-37)52-29-27-44(50-36(5)54)51-47(52)56)31-60-48(38-17-12-9-13-18-38,39-19-23-41(57-6)24-20-39)40-21-25-42(58-7)26-22-40/h8-13,15-27,29,34-35,43,45H,14,30-33H2,1-7H3,(H,50,51,54,56)/t43-,45-,64?/m1/s1
Synonyms: (2R)-2-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-2-(((2R)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)propan-2-yl)oxy)ethyl benzoate; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2R)-2-[(1R)-1-[4-(acetylamino)-2-oxo-1(2H)-pyrimidinyl]-2-(benzoyloxy)ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester; (2R)-2-[(1R)-1-[4-(Acetylamino)-2-oxo-1(2H)-pyrimidinyl]-2-(benzoyloxy)ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite
UNA-U-CE Phosphoramidite
Description: UNA-U-CE Phosphoramidite is a compound utilized in nucleic acid synthesis, particularly in RNA synthesis. It consists of UNA (Unlocked Nucleic Acid), denoted by "UNA," which modifies the nucleotide structure and properties. The "U" signifies uridine as the base, and "CE" indicates cyanoethyl, a protecting group for the phosphate moiety. "Phosphoramidite" refers to the reactive form of the nucleotide used in automated oligonucleotide synthesis. This compound enables controlled addition of modified uridine nucleotides during RNA synthesis for various research and biotechnological applications.
CAT: BRP-00432
CAS: 1120329-48-7
Molecular Formula: C46H53N4O10P
Molecular Weight: 852.91
Purity: ≥98% by HPLC
Appearance: White to off-white powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
InChIKey: MHRGEJFLFYZLJI-LZOZAVILSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)OC(COC(=O)C4=CC=CC=C4)N5C=CC(=O)NC5=O
IUPAC Name: [(2R)-2-[(2R)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]oxy-2-(2,4-dioxopyrimidin-1-yl)ethyl] benzoate
InChI: InChI=1S/C46H53N4O10P/c1-33(2)50(34(3)4)61(58-29-13-27-47)59-31-41(60-43(49-28-26-42(51)48-45(49)53)32-56-44(52)35-14-9-7-10-15-35)30-57-46(36-16-11-8-12-17-36,37-18-22-39(54-5)23-19-37)38-20-24-40(55-6)25-21-38/h7-12,14-26,28,33-34,41,43H,13,29-32H2,1-6H3,(H,48,51,53)/t41-,43-,61?/m1/s1
Synonyms: 5'-(4,4'-dimethoxytrityl)-2'-benzoyl-2',3'-seco-uridine-3'-cyanoethyl Phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2R)-2-[(1R)-2-(benzoyloxy)-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester; 5'-DMTr-2'-Bz-3'-O-CEP-UNA-U; 5'-(4,4'-dimethoxytrityl)-2'-benzoyl-2',3'-seco-uridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)] Phosphoramidite; (2R)-2-[(1R)-2-(Benzoyloxy)-1-(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite
Morpholino G(PhAc) subunit
Description: The Morpholino G(PhAc) subunit is a component used in the synthesis of morpholino oligomers, synthetic analogs of nucleic acids. It features a morpholine ring structure as the backbone, with a guanine base modified by a phenylacetyl group (PhAc). This modification enhances the binding affinity of the oligomers to complementary RNA or DNA targets. The Morpholino G(PhAc) subunit is utilized in molecular biology and biotechnology for applications such as gene knockdown experiments, antisense therapy, and the study of gene function.
CAT: BRP-00433
CAS: 1044241-74-8
Molecular Formula: C39H39ClN7O5P
Molecular Weight: 752.20
Purity: ≥98% by HPLC
Appearance: White to off-white powder
| Size | Price | Stock | Quantity |
|---|---|---|---|
| -- | -- | -- |
Storage: Store at -20 °C
Density: 1.37±0.1 g/cm3
InChIKey: NURVOJDGJURYKG-BFXPVMCSSA-N
CanonicalSMILES: O=C1N=C(NC(=O)CC=2C=CC=CC2)NC3=C1N=CN3C4OC(COP(=O)(Cl)N(C)C)CN(C4)C(C=5C=CC=CC5)(C=6C=CC=CC6)C=7C=CC=CC7
IUPAC Name: ((2S,6R)-6-(6-oxo-2-(2-phenylacetamido)-1,6-dihydro-9H-purin-9-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate
InChI: InChI=1S/C39H39ClN7O5P/c1-45(2)53(40,50)51-26-32-24-46(39(29-17-9-4-10-18-29,30-19-11-5-12-20-30)31-21-13-6-14-22-31)25-34(52-32)47-27-41-35-36(47)43-38(44-37(35)49)42-33(48)23-28-15-7-3-8-16-28/h3-22,27,32,34H,23-26H2,1-2H3,(H2,42,43,44,48,49)/t32-,34+,53?/m0/s1
Synonyms: Phosphoramidochloridic acid, N,N-dimethyl-, [(2S,6R)-6-[1,6-dihydro-6-oxo-2-[(2-phenylacetyl)amino]-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl ester; [(2S,6R)-6-[1,6-Dihydro-6-oxo-2-[(2-phenylacetyl)amino]-9H-purin-9-yl]-4-(triphenylmethyl)-2-morpholinyl]methyl N,N-dimethylphosphoramidochloridate; (2S,6R)-6-(6-oxo-2-(2-phenylacetamido)-1H-purin-9(6H)-yl)-4-tritylmorpholin-2-yl)methyl dimethylphosphoramidochloridate
