Phosphoramidites

2'-Modified Phosphoramidites
(466/466)
2'-Phosphoramidites
(21/21)
3'-Modified Phosphoramidites
(186/186)
5'-Modified Phosphoramidites
(21/21)
Arabino Phosphoramidites
(19/19)
Base Protected Phosphoramidites (365/365) Dye Phosphoramidites
(53/53)
Label Phosphoramidites
(82/82)
Linker Phosphoramidites
(72/72)
Other Phosphoramidites
(92/92)
PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12)
Reverse Phosphoramidites
(15/15)
Spacer Phosphoramidites
(22/22)
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6-FAM-DMT-phosphoramidite

Description: 6-FAM-DMT Phosphoramidite is a phosphoramidite derivative used to introduce 6-carboxyfluorescein (6-FAM) into oligonucleotides during solid-phase synthesis. It includes a 6-FAM fluorophore and a dimethoxytrityl (DMT) protecting group, which facilitates efficient incorporation and subsequent deprotection during synthesis. This reagent enables the production of fluorescently labeled oligonucleotides for applications such as fluorescence-based detection, quantitative PCR (qPCR), and fluorescence resonance energy transfer (FRET) assays.
CAT: BRP-00259
CAS: 316121-60-5
MF: C68H78N3O13P
MF: 1176.33
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Storage: Store at 2-8 °C
InChIKey: ODJKPDRSCITVNU-UHFFFAOYNA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: COC1=CC=C(C=C1)C(OCC(CCCCNC(=O)C1=CC=C2C(=O)OC3(C2=C1)C1=CC=C(OC(=O)C(C)(C)C)C=C1OC1=CC(OC(=O)C(C)(C)C)=CC=C31)COP(OCCC#N)N(C(C)C)C(C)C)(C1=CC=CC=C1)C1=CC=C(OC)C=C1
IUPAC Name: [6-[[5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]carbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1/C68H78N3O13P/c1-44(2)71(45(3)4)85(79-38-18-36-69)80-43-46(42-78-67(48-20-14-13-15-21-48,49-23-27-51(76-11)28-24-49)50-25-29-52(77-12)30-26-50)19-16-17-37-70-61(72)47-22-33-55-58(39-47)68(84-62(55)73)56-34-31-53(81-63(74)65(5,6)7)40-59(56)83-60-41-54(32-35-57(60)68)82-64(75)66(8,9)10/h13-15,20-35,39-41,44-46H,16-19,37-38,42-43H2,1-12H3,(H,70,72)
Synonyms: 6-Fluorescein Phosphoramidite; 2-Dimethoxytrityloxymethyl-6-(3',6'-dipivaloylfluorescein-6-yl-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-6-Fluorescein phosphoramidite (with DMT); Propanoic acid, 2,2-dimethyl-, 6-[7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; DMT-6-FAM phosphoramidite

Cholesteryl-TEG Phosphoramidite

Description: Cholesteryl-TEG Phosphoramidite is an indispensable component in the biomedical sector, exemplifing its significance by facilitating the research and development of altered nucleotides. Its pivotal contribution lies in propelling the progress of groundbreaking pharmaceuticals and therapeutics aimed at studying malignancies, viral affections and hereditary anomalies.
CAT: BRP-00260
CAS: 873435-29-1
MF: C70H106N3O11P
MF: 1196.60
Purity: 95%
Appearance: Colorless to faint yellow oily matter
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InChIKey: FNJSTUYYFCEZCA-PORNTWEGSA-N
CanonicalSMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC(=O)NCCCOCCOCCOCCOCC(COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N)C)C
IUPAC Name: [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] N-[3-[2-[2-[2-[3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropoxy]ethoxy]ethoxy]ethoxy]propyl]carbamate
InChI: InChI=1S/C70H106N3O11P/c1-51(2)18-15-19-54(7)64-32-33-65-63-31-26-58-48-61(34-36-68(58,8)66(63)35-37-69(64,65)9)83-67(74)72-39-17-40-77-42-43-78-44-45-79-46-47-80-49-62(84-85(82-41-16-38-71)73(52(3)4)53(5)6)50-81-70(55-20-13-12-14-21-55,56-22-27-59(75-10)28-23-56)57-24-29-60(76-11)30-25-57/h12-14,20-30,51-54,61-66H,15-19,31-37,39-50H2,1-11H3,(H,72,74)/t54-,61+,62?,63+,64-,65+,66+,68+,69-,85?/m1/s1
Synonyms: 1-Dimethoxytrityloxy-3-O-(N-cholesteryl-3-aminopropyl)-triethyleneglycol-glyceryl-2-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Cholest-5-en-3-ol (3β)-, 3-[17-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-19-[bis(1-methylethyl)amino]-22-cyano-6,9,12,15,18,20-hexaoxa-2-aza-19-phosphadocosanoate]; Cholesteryl TEG phosphoramidite; Cholest-5-en-3-ol (3β)-, 17-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-19-[bis(1-methylethyl)amino]-22-cyano-6,9,12,15,18,20-hexaoxa-2-aza-19-phosphadocosanoate; Dimethoxytrityloxy-3-O-(N-cholesteryl-3-aminopropyl)triethyleneglycol-glyceryl-2-O-(2-cyanoethyl)(N,N-diisopropyl)phosphoramidite; DMTr-Cholesteryl-TEG Phosphoramidite (plant source); 1-O-(4,4'-dimethoxytrityl)-3-O-(N-cholesteryl-3-aminopropyl)-triethyleneglycol-glyceryl-2-O-(2-cyanoethyl)-(N,N-diisopropyl) Phosphoramidite; DMT-Cholesterol (Plant) TEG CE phosphoramidite

Psoralen-C2 CEP

Description: Psoralen-C2 CEP is an innovative biomedical compound, used for studying a myriad of skin afflictions, particularly psoriasand vitiligo. It is derived from psoralen, an organic constituent inherent to select flora.
CAT: BRP-00261
CAS: 126221-83-8
MF: C26H35N2O6P
MF: 502.55
Purity: 95%
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InChIKey: DBDHKKULBPYUPD-UHFFFAOYSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC1=CC(=O)OC2=C(C3=C(C=C12)C(=C(O3)C)COCCOP(N(C(C)C)C(C)C)OCCC#N)C
IUPAC Name: 3-[[di(propan-2-yl)amino]-[2-[(2,5,9-trimethyl-7-oxofuro[3,2-g]chromen-3-yl)methoxy]ethoxy]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C26H35N2O6P/c1-16(2)28(17(3)4)35(31-10-8-9-27)32-12-11-30-15-23-20(7)33-26-19(6)25-21(14-22(23)26)18(5)13-24(29)34-25/h13-14,16-17H,8,10-12,15H2,1-7H3
Synonyms: 2-[4'-(hydroxymethyl)-4,5',8-trimethylpsoralen]-ethyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Psoralen C2 Phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 2-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]ethyl ester; 2-Cyanoethyl (2-((2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)methoxy)ethyl) diisopropylphosphoramidite; Psoralen C-2 CED phosphoramidite

Psoralen C6 Phosphoramidite

Description: Psoralen C6 Phosphoramidite is an indispensable compound, finding extensive employment in DNA synthesis and modification. This remarkable product effectively facilitates the incorporation of psoralen derivatives into oligonucleotides, thereby enabling the research of an extensive array of afflictions encompassing cancer and dermatological conditions.
CAT: BRP-00262
CAS: 518046-08-7
MF: C30H43N2O6P
MF: 558.65
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InChIKey: VBVUJRRJLYZYNP-UHFFFAOYSA-N
CanonicalSMILES: CC1=CC(=O)OC2=C(C3=C(C=C12)C(=C(O3)C)COCCCCCCOP(N(C(C)C)C(C)C)OCCC#N)C
IUPAC Name: 3-[[di(propan-2-yl)amino]-[6-[(2,5,9-trimethyl-7-oxofuro[3,2-g]chromen-3-yl)methoxy]hexoxy]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C30H43N2O6P/c1-20(2)32(21(3)4)39(36-16-12-13-31)35-15-11-9-8-10-14-34-19-27-24(7)37-30-23(6)29-25(18-26(27)30)22(5)17-28(33)38-29/h17-18,20-21H,8-12,14-16,19H2,1-7H3
Synonyms: 6-[4'-(Hydroxymethyl)-4,5',8-trimethylpsoralen]-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 6-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]hexyl ester; Psoralen C-6 CED phosphoramidite; 2-Cyanoethyl 6-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]hexyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 6-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]hexyl ester; Psoralen-C6 CEP

DNP-TEG CEP

Description: DNP-TEG CEP is a prominent biomedical compound, used in research of mitochondrial dysfunction. In its remarkable capacity as a mitochondrial uncoupler, it efficaciously facilitates energy dissipation while curbing ATP synthesis. Notably, this revolutionary compound exhibits immense promise in studying the burden of metabolic disorders like obesity and diabetes.
CAT: BRP-00263
CAS: 1027512-01-1
MF: C48H64N5O13P
MF: 950.02
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InChIKey: QMUUCQCGRWITRM-UHFFFAOYSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: N#CCCOP(OC(COCCOCCOCCOCCCNC1=CC=C(C=C1N(=O)=O)N(=O)=O)COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N(C(C)C)C(C)C
IUPAC Name: 2-cyanoethyl (18-((2,4-dinitrophenyl)amino)-1,1-bis(4-methoxyphenyl)-1-phenyl-2,6,9,12,15-pentaoxaoctadecan-4-yl) diisopropylphosphoramidite
InChI: InChI=1S/C48H64N5O13P/c1-37(2)51(38(3)4)67(65-27-10-24-49)66-45(35-63-33-32-62-31-30-61-29-28-60-26-11-25-50-46-23-18-42(52(54)55)34-47(46)53(56)57)36-64-48(39-12-8-7-9-13-39,40-14-19-43(58-5)20-15-40)41-16-21-44(59-6)22-17-41/h7-9,12-23,34,37-38,45,50H,10-11,25-33,35-36H2,1-6H3
Synonyms: 1-Dimethoxytrityloxy-3-O-[N-(2,4-dinitrophenyl)-3-N-aminopropyl-(triethyleneglycol)]-glyceryl-2-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; DNP-TEG Phosphoramidite; 1-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-15-[(2,4-dinitrophenyl)amino]-3,6,9,12-tetraoxapentadec-1-yl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-15-[(2,4-dinitrophenyl)amino]-3,6,9,12-tetraoxapentadec-1-yl 2-cyanoethyl ester; DNP-TEG CED phosphoramidite

Alkyne-Modifier Serinol Phosphoramidite

Description: Alkyne-Modifier Serinol Phosphoramidite is a potent chemical reagent that pervasively aids in the synthesis of oligonucleotides for biomedical research purposes. Its proficiency lies in the assortment, stability, solubility enhancement and augmented bioavailability of DNA and RNA modification. Not only that, it proficiently gets the job done in developing gene therapies with targeted drug delivery systems for treating ailments like cancer, viral infections, and genetic disorders.
CAT: BRP-00264
CAS: 2084118-98-7
MF: C42H55N4O7P
MF: 758.88
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InChIKey: AGVCOEQZDILAFH-UHFFFAOYSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)NC(=O)CCNC(=O)CCCC#C
IUPAC Name: N-[3-[[1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]amino]-3-oxopropyl]hex-5-ynamide
InChI: InChI=1S/C42H55N4O7P/c1-8-9-11-17-40(47)44-28-26-41(48)45-37(31-53-54(52-29-14-27-43)46(32(2)3)33(4)5)30-51-42(34-15-12-10-13-16-34,35-18-22-38(49-6)23-19-35)36-20-24-39(50-7)25-21-36/h1,10,12-13,15-16,18-25,32-33,37H,9,11,14,17,26,28-31H2,2-7H3,(H,44,47)(H,45,48)
Synonyms: 3-Dimethoxytrityloxy-2-(3-(5-hexynamido)propanamido)propyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 3-[bis(4-methoxyphenyl)phenylmethoxy]-2-[[1-oxo-3-[(1-oxo-5-hexyn-1-yl)amino]propyl]amino]propyl 2-cyanoethyl ester; 3-[Bis(4-methoxyphenyl)phenylmethoxy]-2-[[1-oxo-3-[(1-oxo-5-hexyn-1-yl)amino]propyl]amino]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite

Dithiol Serinol Phosphoramidite

Description: Dithiol Serinol Phosphoramidite is a key component in the synthesis of mRNA vaccines used to combat diseases like COVID-19. This compound provides a crucial thiol group that creates a stable linkage between mRNA and its delivery vehicle, enabling efficient cellular uptake and protein translation.
CAT: BRP-00265
MF: C44H61N4O7PS2
MF: 853.08
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InChIKey: DVWHOVJDNIOLBR-NDSIFBHOSA-N
Solubility: Soluble in Anhydrous Acetonitrile
IUPAC Name: 2-(3-(5-((R)-1,2-dithiolan-3-yl)pentanamido)propanamido)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C44H61N4O7PS2/c1-33(2)48(34(3)4)56(54-29-12-27-45)55-32-38(47-43(50)25-28-46-42(49)16-11-10-15-41-26-30-57-58-41)31-53-44(35-13-8-7-9-14-35,36-17-21-39(51-5)22-18-36)37-19-23-40(52-6)24-20-37/h7-9,13-14,17-24,33-34,38,41H,10-12,15-16,25-26,28-32H2,1-6H3,(H,46,49)(H,47,50)/t38?,41-,56?/m1/s1
Synonyms: 3-Dimethoxytrityloxy-2-(3-((R)-α-lipoamido)propanamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite

Protected Biotin Serinol Phosphoramidite

Description: Protected Biotin Serinol Phosphoramidite is a biomedicine product used in DNA synthesis for biotin labeling. It serves as a phosphate protecting agent during the synthesis of biotinylated oligonucleotides used in disease diagnostics, gene expression analysis, and biosensor development.
CAT: BRP-00266
CAS: 1275574-85-0
MF: C57H75N6O9PS
MF: 1051.28
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InChIKey: FKQJXAHANDDQSD-IKNNSCCISA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: N#CCCOP(OCC(NC(=O)CCNC(=O)CCCCC1SCC2N(C(=O)NC12)C(=O)C3=CC=C(C=C3)C(C)(C)C)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: 3-(bis(4-methoxyphenyl)(phenyl)methoxy)-2-(3-(5-((3aS,4S,6aR)-1-(4-(tert-butyl)benzoyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)propanamido)propyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C57H75N6O9PS/c1-39(2)63(40(3)4)73(71-35-15-33-58)72-37-46(36-70-57(43-16-11-10-12-17-43,44-24-28-47(68-8)29-25-44)45-26-30-48(69-9)31-27-45)60-52(65)32-34-59-51(64)19-14-13-18-50-53-49(38-74-50)62(55(67)61-53)54(66)41-20-22-42(23-21-41)56(5,6)7/h10-12,16-17,20-31,39-40,46,49-50,53H,13-15,18-19,32,34-38H2,1-9H3,(H,59,64)(H,60,65)(H,61,67)/t46?,49-,50-,53-,73?/m0/s1
Synonyms: 3-Dimethoxytrityloxy-2-(3-((4-t-butylbenzoyl)-biotinyl)propanamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 3-[Bis(4-methoxyphenyl)phenylmethoxy]-2-[[3-[[5-[(3aS,4S,6aR)-1-[4-(1,1-dimethylethyl)benzoyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-1-oxopropyl]amino]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 3-[bis(4-methoxyphenyl)phenylmethoxy]-2-[[3-[[5-[(3aS,4S,6aR)-1-[4-(1,1-dimethylethyl)benzoyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-1-oxopropyl]amino]propyl 2-cyanoethyl ester

6-Fluorescein Serinol Phosphoramidite

Description: 6-Fluorescein Serinol Phosphoramidite, a high-potency biocompatible fluorescent probe, finds extensive application in bioconjugation and labeling strategies for DNA and RNA synthesis. With its lucid capability to detect DNA and RNA oligonucleotides in fluorescence microscopy experiments, it has become a quintessential tool for hybridization assays. Its immense potential in modern biological research has termed it as a breakthrough innovation in the field of biochemistry and biophysics.
CAT: BRP-00267
CAS: 1275574-87-2
MF: C67H75N4O14P
MF: 1191.30
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InChIKey: GIUBJQWDYGXGQR-UHFFFAOYSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)NC(=O)CCNC(=O)C4=CC5=C(C=C4)C(=O)OC56C7=C(C=C(C=C7)OC(=O)C(C)(C)C)OC8=C6C=CC(=C8)OC(=O)C(C)(C)C
IUPAC Name: [6-[[3-[[1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]amino]-3-oxopropyl]carbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C67H75N4O14P/c1-42(2)71(43(3)4)86(80-36-16-34-68)81-41-48(40-79-66(45-17-14-13-15-18-45,46-20-24-49(77-11)25-21-46)47-22-26-50(78-12)27-23-47)70-59(72)33-35-69-60(73)44-19-30-53-56(37-44)67(85-61(53)74)54-31-28-51(82-62(75)64(5,6)7)38-57(54)84-58-39-52(29-32-55(58)67)83-63(76)65(8,9)10/h13-15,17-32,37-39,42-43,48H,16,33,35-36,40-41H2,1-12H3,(H,69,73)(H,70,72)
Synonyms: 3-Dimethoxytrityloxy-2-(3-(6-carboxy-(di-O-pivaloyl-fluorescein)propanamido)propyl)-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Propanoic acid, 2,2-dimethyl-, 1,1'-[6-[7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-1,5-dioxo-9,11-dioxa-2,6-diaza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] ester; 1,1'-[6-[7-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-1,5-dioxo-9,11-dioxa-2,6-diaza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] bis(2,2-dimethylpropanoate)

Protected BiotinLC Serinol Phosphoramidite

Description: Protected BiotinLC Serinol Phosphoramidite, a derivative of biotin and serinol, has been clinically proven to be an exceptional and highly-effective reagent for synthesizing DNA and RNA probes. With its myriad of applications, this reagent is a versatile choice for professionals in the field of tissue imaging and protein interaction studies. A key component in the creation of oligonucleotides, aptamers, and siRNA, Protected BiotinLC Serinol Phosphoramidite deftly performs a plethora of bioanalytical tasks with the utmost precision and accuracy.
CAT: BRP-00268
MF: C68H96N7O14PS
MF: 1298.57
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InChIKey: LLAFADMXMWCLJQ-XRKNHYQJSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)CCCCC4C5C(CS4)N(C(=O)N5)C(=O)C6=CC=C(C=C6)C(C)(C)C
IUPAC Name: 2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-28-((3aS,4S,6aR)-1-(4-(tert-butyl)benzoyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,8,24-trioxo-6,13,16,19-tetraoxa-3,9,23-triazaoctacosyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C68H96N7O14PS/c1-49(2)75(50(3)4)90(88-39-15-34-69)89-45-56(44-87-68(53-18-11-10-12-19-53,54-26-30-57(81-8)31-27-54)55-28-32-58(82-9)33-29-55)72-63(78)47-86-46-62(77)71-36-17-38-84-41-43-85-42-40-83-37-16-35-70-61(76)21-14-13-20-60-64-59(48-91-60)74(66(80)73-64)65(79)51-22-24-52(25-23-51)67(5,6)7/h10-12,18-19,22-33,49-50,56,59-60,64H,13-17,20-21,35-48H2,1-9H3,(H,70,76)(H,71,77)(H,72,78)(H,73,80)/t56?,59-,60-,64-,90?/m0/s1
Synonyms: 3-Dimethoxytrityloxy-2-(3-((4-t-butylbenzoyl)-biotinyl-3-aminopropyl)-diethyleneglycolyl-propylamido-glycanoylamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite

Amino-Modifier Serinol Phosphoramidite

Description: Amino-Modifier Serinol Phosphoramidite, a chemical reagent synonymous with biomedical synthesis, plays a key role in the modification of oligonucleotides - mercifully, chock-full of amino functionalities. As a potent building block, this product holds potential for therapeutic and diagnostic development, with applications pertaining to the likes of cancer, viral infections, and genetic disorders. Well-renowned for its high purity and stability, it remains a stand-out performer in the realm of gene therapy and all matters nucleic acid drug delivery.
CAT: BRP-00269
CAS: 196297-83-3
MF: C51H59N4O8P
MF: 887.01
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Storage: Store at -20°C
Boiling Point: 938.0±65.0 °C at 760 mmHg
InChIKey: AYVWOMBHOQDZKA-UHFFFAOYSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)NC(=O)CCNC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
IUPAC Name: 9H-fluoren-9-ylmethyl N-[3-[[1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]amino]-3-oxopropyl]carbamate
InChI: InChI=1S/C51H59N4O8P/c1-36(2)55(37(3)4)64(62-32-14-30-52)63-34-41(54-49(56)29-31-53-50(57)60-35-48-46-19-12-10-17-44(46)45-18-11-13-20-47(45)48)33-61-51(38-15-8-7-9-16-38,39-21-25-42(58-5)26-22-39)40-23-27-43(59-6)28-24-40/h7-13,15-28,36-37,41,48H,14,29,31-35H2,1-6H3,(H,53,57)(H,54,56)
Synonyms: 3-Dimethoxytrityloxy-2-(3-(fluorenylmethoxycarbonylamino)propanamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 9-Oxa-2,6,11-triaza-10-phosphatridecanoic acid, 7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-(2-cyanoethoxy)-12-methyl-11-(1-methylethyl)-5-oxo-, 9H-fluoren-9-ylmethyl ester; 9,11-Dioxa-2,6-diaza-10-phosphatridecanoic acid, 7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-[bis(1-methylethyl)amino]-13-cyano-5-oxo-, 9H-fluoren-9-ylmethyl ester; 9H-Fluoren-9-ylmethyl 7-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-(2-cyanoethoxy)-12-methyl-11-(1-methylethyl)-5-oxo-9-oxa-2,6,11-triaza-10-phosphatridecanoate

DBCO-Serinol Phosphoramidite

Description: DBCO-Serinol Phosphoramidite is a quintessential reagent for biomedical research, a chemical compound that is omnipresent in the lab benches of esteemed molecular biologists. This versatile oligonucleotide synthesizer is engineered to conjugate with various biomolecules for a plethora of drug delivery and bioimaging applications.
CAT: BRP-00270
MF: C54H61N4O7P
MF: 909.08
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InChIKey: VOACHPAMSJFKOH-UHFFFAOYSA-N
CanonicalSMILES: O=C(NC(COP(OCCC#N)N(C(C)C)C(C)C)COC(C1=CC=C(OC)C=C1)(C2=CC=C(OC)C=C2)C3=CC=CC=C3)CCCCC(N4C(C=CC=C5)=C5C#CC(C=CC=C6)=C6C4)=O
InChI: InChI=1S/C54H61N4O7P/c1-40(2)58(41(3)4)66(64-36-16-35-55)65-39-48(38-63-54(45-20-8-7-9-21-45,46-27-31-49(61-5)32-28-46)47-29-33-50(62-6)34-30-47)56-52(59)23-14-15-24-53(60)57-37-44-19-11-10-17-42(44)25-26-43-18-12-13-22-51(43)57/h7-13,17-22,27-34,40-41,48H,14-16,23-24,36-39H2,1-6H3,(H,56,59)
Synonyms: 3-Dimethoxytrityloxy-2-(6-oxo-6-(dibenzo[b,f]azacyclooct-4-yn-1-yl)-capramido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite

Azobenzene Phosphoramidite

Description: Azobenzene phosphoramidite, a synthetic molecule utilized in biomedicine to modify the DNA and RNA, is a photoswitch aiding light-dependent control of gene expression. Researched to treat cancer, viral infections and neurological disorders, Azobenzene phosphoramidite proves promising.
CAT: BRP-00271
CAS: 1227873-20-2
MF: C47H54N5O6P
MF: 815.94
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InChIKey: HWVZOGDVVZLMFF-AKCAFWOHSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: N#CCCOP(OC(C)C(NC(=O)C1=CC=C(N=NC=2C=CC=CC2)C=C1)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C
IUPAC Name: (2S,3S)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(4-(phenyldiazenyl)benzamido)butan-2-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C47H54N5O6P/c1-34(2)52(35(3)4)59(57-32-14-31-48)58-36(5)45(49-46(53)37-19-25-42(26-20-37)51-50-41-17-12-9-13-18-41)33-56-47(38-15-10-8-11-16-38,39-21-27-43(54-6)28-22-39)40-23-29-44(55-7)30-24-40/h8-13,15-30,34-36,45H,14,32-33H2,1-7H3,(H,49,53)/t36-,45-,59?/m0/s1
Synonyms: 3-O-(Dimethoxytrityl)-2-N-(4-carboxyazobenzene)-D-threonin-1-yl-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S,2S)-3-[bis(4-methoxyphenyl)phenylmethoxy]-1-methyl-2-[[4-(2-phenyldiazenyl)benzoyl]amino]propyl 2-cyanoethyl ester; (1S,2S)-3-[Bis(4-methoxyphenyl)phenylmethoxy]-1-methyl-2-[[4-(2-phenyldiazenyl)benzoyl]amino]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite

SIMA phosphoramidite, 6-isomer

Description: SIMA (dichloro-diphenyl-fluorescein) is a xanthene dye with spectral characteristics similar to those of HEX but with a higher quantum yield. SIMA phosphoramidite is used in oligonucleotide synthesis to produce fluorescently labeled primers and hybridization probes for quantitative PCR.
CAT: BRP-00272
CAS: 1411797-05-1
MF: C58H64N3Cl2O10P
MF: 1065.02
Appearance: White Powder
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InChIKey: WPCMEEMVKXSQGE-UHFFFAOYSA-N
Solubility: Soluble in acetonitrile and DCM
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)C1=CC(=C2C(=C1Cl)C3(C4=C(C=C(C(=C4)C5=CC=CC=C5)OC(=O)C(C)(C)C)OC6=C3C=C(C(=C6)OC(=O)C(C)(C)C)C7=CC=CC=C7)OC2=O)Cl)OCCC#N
IUPAC Name: [4,7-dichloro-6-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxo-2',7'-diphenylspiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C58H64Cl2N3O10P/c1-35(2)63(36(3)4)74(69-29-21-26-61)68-28-20-12-11-19-27-62-52(64)41-32-44(59)49-50(51(41)60)58(73-53(49)65)42-30-39(37-22-15-13-16-23-37)45(71-54(66)56(5,6)7)33-47(42)70-48-34-46(72-55(67)57(8,9)10)40(31-43(48)58)38-24-17-14-18-25-38/h13-18,22-25,30-36H,11-12,19-21,27-29H2,1-10H3,(H,62,64)
Synonyms: 6-(4,7-Dichloro-2',7'-diphenyl-3',6'-dipivaloylfluorescein-6-carboxamido)-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Propanoic acid, 2,2-dimethyl-, 1,1'-[6-[10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-4,7-dichloro-3-oxo-2',7'-diphenylspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] ester; 1,1'-[6-[10-[Bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-4,7-dichloro-3-oxo-2',7'-diphenylspiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] bis(2,2-dimethylpropanoate); SIMA; SIMA phosphoramidite, 6-isomer

Redmond Red® Phosphoramidite

Description: Redmond Red® Phosphoramidite, a paramount element utilized in the fabrication of tagged oligonucleotides, holds pivotal value regarding diagnostic utilities namely therapeutic RNA sequencing and genotyping assays. Additionally, it exhibits noteworthy application towards the treatment of hereditary maladies such as cystic fibrosis and Huntington's disease.
CAT: BRP-00273
CAS: 909906-38-3
MF: C55H63N4O10P
MF: 971.09
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InChIKey: ZRDCBBFLELRHPG-OGAYPNLZSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: N#CCCOP(OC1CN(C(=O)CCC2=CC3=NC=4C=CC(OC(=O)C(C)(C)C)=CC4OC3=CC2=O)C(COC(C=5C=CC=CC5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7)C1)N(C(C)C)C(C)C
IUPAC Name: 2-(3-((2S,4R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)pyrrolidin-1-yl)-3-oxopropyl)-3-oxo-3H-phenoxazin-7-yl pivalate
InChI: InChI=1S/C55H63N4O10P/c1-36(2)59(37(3)4)70(66-29-13-28-56)69-46-31-42(35-65-55(39-14-11-10-12-15-39,40-17-21-43(63-8)22-18-40)41-19-23-44(64-9)24-20-41)58(34-46)52(61)27-16-38-30-48-51(33-49(38)60)68-50-32-45(25-26-47(50)57-48)67-53(62)54(5,6)7/h10-12,14-15,17-26,30,32-33,36-37,42,46H,13,16,27,29,31,34-35H2,1-9H3/t42-,46+,70?/m0/s1
Synonyms: 3-(3-oxo-7-pivaloylphenoxazin-2-yl)-propanamido-1-(2-O-dimethoxytrityloxymethyl)-pyrrolidin-4-yl-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Propanoic acid, 2,2-dimethyl-, 2-[3-[(2S,4R)-2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-4-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]-1-pyrrolidinyl]-3-oxopropyl]-3-oxo-3H-phenoxazin-7-yl ester; 2-[3-[(2S,4R)-2-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-4-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]-1-pyrrolidinyl]-3-oxopropyl]-3-oxo-3H-phenoxazin-7-yl 2,2-dimethylpropanoate

5'-AquaPhluor® 593 CE Phosphoramidite

Description: 5'-AquaPhluor® 593 CE Phosphoramidite, a premium compound of utmost finesse, plays a central role in the realm of oligonucleotide development. Its distinguished fluorescence labeling attribute is deftly infused into the backbone of oligonucleotides, vastly facilitating the discernment of DNA, RNA and DNA-protein interactions. Enabling cutting-edge genetic inquiry, this invaluable substance is a critical tool in biomedicine research, aiding in the detection and scrutiny of DNA and RNA sequences, as well as the diagnosis of genetic disorders.
CAT: BRP-00274
CAS: 2378004-17-0
MF: C57H78F9N6O8P3
MF: 1239.17
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InChIKey: DWHRLIUARJHFGF-UHFFFAOYSA-O
CanonicalSMILES: N#CCCOP(OCCCCCCOP(=O)(OCCCCNC(=O)C(F)(F)F)C=1C=CC(C(=O)N(CC)CC)=C(C1)C=2C=3C=C4C5=C(C3[O+]=C6C2C=C7C8=C6CCCN8CCC7)CCCN5CCC4)N(C(C)C)C(C)C.[F-][P+5]([F-])([F-])([F-])([F-])[F-]
InChI: InChI=1S/C57H77F3N6O8P2.F6P/c1-7-63(8-2)55(67)44-25-24-43(76(69,73-35-14-11-27-62-56(68)57(58,59)60)72-34-13-10-9-12-32-70-75(71-33-19-26-61)66(39(3)4)40(5)6)38-47(44)50-48-36-41-20-15-28-64-30-17-22-45(51(41)64)53(48)74-54-46-23-18-31-65-29-16-21-42(52(46)65)37-49(50)54;1-7(2,3,4,5)6/h24-25,36-40H,7-23,27-35H2,1-6H3;/q;-1/p+1
Synonyms: 6-[2,3,6,7,12,13,16,17-Octohydro-1H,5H,11H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium-9-yl-[(2-diethylaminocarbonyl)-phen-4-yl][trifluoroacetylaminobutoxy]phosphoryl][oxy]]-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite,hexafluorophosphate salt; 1H,5H,11H,15H-Quinolizino[1',9':5,6,7]xantheno[2,3,4-ij]quinolizin-18-ium, 9-[5-[10-[bis(1-methylethyl)amino]-13-cyano-1-oxido-1-[4-[(2,2,2-trifluoroacetyl)amino]butoxy]-2,9,11-trioxa-1,10-diphosphatridec-1-yl]-2-[(diethylamino)carbonyl]phenyl]-2,3,6,7,12,13,16,17-octahydro-, hexafluorophosphate(1-) (1:1)
Related CAS: 2378004-16-9 (free base)

5'-BBQ-650®-CE Phosphoramidite

Description: 5'-BBQ-650®-CE Phosphoramidite is a highly complex and exceedingly versatile chemical reagent that boasts an impressive array of applications in the realms of oligonucleotide synthesis, bioimaging, diagnostics, gene expression and genetic disorders. Infused with a fluorescent marker, this stunningly sophisticated product is capable of facilitating easy detection and in-depth analysis of a wide range of biological phenomena.
CAT: BRP-00275
CAS: 1027512-25-9
MF: C41H55N8O7P
MF: 802.90
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InChIKey: QDVVHDWLKVWLFU-UHFFFAOYSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCOC1=C(C=C2CCCN3C2=C1CCC3)N=NC4=C(C=C(C(=C4)OC)N=NC5=CC=C(C=C5)[N+](=O)[O-])OC)OCCC#N
IUPAC Name: 3-[6-[[7-[[2,5-dimethoxy-4-[(4-nitrophenyl)diazenyl]phenyl]diazenyl]-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8-trien-6-yl]oxy]hexoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C41H55N8O7P/c1-29(2)48(30(3)4)57(56-25-13-20-42)55-24-10-8-7-9-23-54-41-34-15-12-22-47-21-11-14-31(40(34)47)26-37(41)46-45-36-28-38(52-5)35(27-39(36)53-6)44-43-32-16-18-33(19-17-32)49(50)51/h16-19,26-30H,7-15,21-25H2,1-6H3
Synonyms: 5'-BBQ-650 CEP; 9-[4-Nitro-2',5'-dimethoxy-azobenz-4'-yl)-diazo]-julolidine-8]-O-hexyl-[2-cyanoethyl-(N,N-diisopropyl)]-phosphoramidite; 5'-BBQ-650 CE-Phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 6-[[9-[2-[2,5-dimethoxy-4-[2-(4-nitrophenyl)diazenyl]phenyl]diazenyl]-2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizin-8-yl]oxy]hexyl ester; 2-Cyanoethyl 6-[[9-[2-[2,5-dimethoxy-4-[2-(4-nitrophenyl)diazenyl]phenyl]diazenyl]-2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizin-8-yl]oxy]hexyl N,N-bis(1-methylethyl)phosphoramidite

5'-AquaPhluor® 639 CE Phosphoramidite

Description: 5'-AquaPhluor® 639 CE Phosphoramidite is a chemical reagent widely used in the biomedicine industry for efficient labeling of synthetic oligonucleotides. This product is capable of introducing fluorescent dyes into the oligonucleotides for multi-color detection and analysis of RNA and DNA sequences. Its high brightness and stability make it suitable for use in various molecular diagnostic applications, including for infectious diseases, cancer diagnosis, and gene expression analysis.
CAT: BRP-00276
MF: C62H82ClF3N6O11P2S
MF: 1273.82
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InChIKey: JREHZANXZDRQFA-UHFFFAOYSA-N
CanonicalSMILES: CC(N(P(OCCC#N)OCCCCCCOP(C1=CC(C(N(C)CCS(=O)([O-])=O)=O)=C(C(C2=C3C4=C5C(C(C)=CC(C)(C)N5CCC4)=C2)=C6C=C7C(C)=CC(C)(C)N8CCCC(C6=[O+]3)=C78)C(Cl)=C1)(OCCCCNC(C(F)(F)F)=O)=O)C(C)C)C
InChI: InChI=1S/C62H82ClF3N6O11P2S/c1-39(2)72(40(3)4)84(80-29-20-23-67)79-28-15-12-13-16-30-81-85(75,82-31-17-14-24-68-59(74)62(64,65)66)43-33-50(58(73)69(11)27-32-86(76,77)78)53(51(63)34-43)52-48-35-46-41(5)37-60(7,8)70-25-18-21-44(54(46)70)56(48)83-57-45-22-19-26-71-55(45)47(36-49(52)57)42(6)38-61(71,9)10/h33-40H,12-22,24-32H2,1-11H3,(H-,68,74,76,77,78)
Synonyms: 6-[2,3,16,17-tetrahydro-5,5,7,11,13,13-hexamethyl-1H,5H,13H,15H-Xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium-9-yl-[2-chloro-6-(N-hydroxysulfonylethyl-N'-methylaminocarbonyl)-phen-4-yl][trifluoroacetylaminobutoxy]phosphoryl][oxy]-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite

Methylene Blue II Phosphoramidite

Description: Methylene Blue II Phosphoramidite is a tool compound used in gene synthesis procedures. It serves as a reagent for the introduction of a non-fluorescent molecule, which is converted into a fluorescent moiety after deprotection during oligonucleotide synthesis.
CAT: BRP-00277
MF: C54H69ClN5O5PS
MF: 966.66
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Storage: Store at -20°C
InChIKey: LMAFXDVQHZECFP-UHFFFAOYSA-M
CanonicalSMILES: CCCCN(C1=CC2=[S+]C3=CC(N(CCCC)CCOC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)=CC=C3N=C2C=C1)CCOP(OCCC#N)N(C(C)C)C(C)C.[Cl-]
IUPAC Name: 3-((2-(bis(4-methoxyphenyl)(phenyl)methoxy)ethyl)(butyl)amino)-7-(butyl(2-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)ethyl)amino)phenothiazin-5-ium;chloride
InChI: InChI=1S/C54H69N5O5PS.ClH/c1-9-11-32-57(34-37-62-54(43-17-14-13-15-18-43,44-19-25-48(60-7)26-20-44)45-21-27-49(61-8)28-22-45)46-23-29-50-52(39-46)66-53-40-47(24-30-51(53)56-50)58(33-12-10-2)35-38-64-65(63-36-16-31-55)59(41(3)4)42(5)6;/h13-15,17-30,39-42H,9-12,16,32-38H2,1-8H3;1H/q+1;/p-1
Synonyms: 3-Butyl-3-[2-(2-cyanoethyl)(N,N-diisopropyl)phosphoramidityl)ethyl]amino-7-(2-(4,4'-dimethoxytrityloxy)ethyl)-7-(butylamino)phenothiazin-5-ium chloride

2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite

Description: 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite is a chemical compound used in the synthesis of oligonucleotides. It serves as a phosphoramidite building block, facilitating the addition of nucleotide units during solid-phase oligonucleotide synthesis. The cyanoethyl group protects the phosphorus atom, while the tetraisopropylphosphorodiamidite moiety enables efficient coupling reactions with nucleotides. This reagent plays a crucial role in the automated synthesis of oligonucleotides, allowing for the controlled assembly of DNA or RNA sequences with high purity and yield.
CAT: BRP-00307
CAS: 102691-36-1
MF: C15H32N3OP
MF: 301.41
Purity: ≥95%
Appearance: Clear Light Yellow Oily Matter
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Storage: Store at 2-8°C under inert atmosphere
Density: 0.949 g/mL at 25°C
Boiling Point: 298.1±0.0°C at 760 mmHg
InChIKey: RKVHNYJPIXOHRW-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile (Slightly), Benzene, Chloroform (Slightly), Methanol (Slightly)
CanonicalSMILES: CC(C)N(C(C)C)P(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: 3-bis[di(propan-2-yl)amino]phosphanyloxypropanenitrile
InChI: InChI=1S/C15H32N3OP/c1-12(2)17(13(3)4)20(19-11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3
Synonyms: N,N,N',N'-Tetrakis(1-methylethyl)phosphorodiamidous Acid 2-Cyanoethyl Ester; 2-Cyanoethoxy bis(N,N-diisopropylamino)phosphine; 2-Cyanoethyl Tetraisopropylphosphorodiamidite; Bis(diisopropylamino)(2-cyanoethoxy)phosphine; 3-((Bis(diisopropylamino)phosphino)oxy)propanenitrile
* Only for research. Not suitable for any diagnostic or therapeutic use.
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