Phosphoramidites

Description: XIMA Phosphoramidite II is a chemical compound used in oligonucleotide synthesis, particularly in the field of molecular biology and biotechnology. It is a type of phosphoramidite reagent that enables the efficient and precise incorporation of nucleotides during the synthesis of DNA and RNA oligonucleotides. XIMA Phosphoramidite II is valued for its high coupling efficiency and stability, making it a reliable choice for the synthesis of oligonucleotides for various applications, including gene synthesis, PCR primers, and nucleic acid aptamers.

CAT: BRP-00473

MF: C84H89Cl2N4O14P

MF: 1480.52

Description: XIMA Phosphoramidite II is a chemical compound used in oligonucleotide synthesis, particularly in the field of molecular biology and biotechnology. It is a type of phosphoramidite reagent that enables the efficient and precise incorporation of nucleotides during the synthesis of DNA and RNA oligonucleotides. XIMA Phosphoramidite II is valued for its high coupling efficiency and stability, making it a reliable choice for the synthesis of oligonucleotides for various applications, including gene synthesis, PCR primers, and nucleic acid aptamers.

CAT: BRP-00473

MF: C84H89Cl2N4O14P

MF: 1480.52

Description: CALF Red 610 Phosphoramidite is a fluorescent compound with an excitation peak of 590 nm and an emission peak of 610 nm. CALF Red 610 Phosphoramidite is spectroscopically similar to SunRed, Alexa Fluor 594, iFluor 594, Texas Red, and California Red. It is a classic dye for apoptosis and necrosis, as well as for polypeptide and oligonucleotide labeling.

CAT: BRP-00474

CAS: 861143-34-2

MF: C46H57N5O4P.F6P

MF: 919.92

Purity: ≥95%

Appearance: Red solid

Description: CALF Red 610 Phosphoramidite is a fluorescent compound with an excitation peak of 590 nm and an emission peak of 610 nm. CALF Red 610 Phosphoramidite is spectroscopically similar to SunRed, Alexa Fluor 594, iFluor 594, Texas Red, and California Red. It is a classic dye for apoptosis and necrosis, as well as for polypeptide and oligonucleotide labeling.

CAT: BRP-00474

CAS: 861143-34-2

MF: C46H57N5O4P.F6P

MF: 919.92

Purity: ≥95%

Appearance: Red solid

Description: Aquafluor 593 is a highly fluorescent molecule with maximum absorption at 593 nm and maximum emission at 613 nm, with a quantum yield of 0.6. The fluorescence of Aquafluor 593 is very little affected by pH, with only a few percent variation in the pH range of 5-8. Moreover, when heated from 20°C to 95°C, the fluorescence only decreased by about 30%.

CAT: BRP-00476

CAS: 2378004-16-9

MF: C57H78F3N6O8P2+

MF: 1094.23

Description: Quasar 670 Phosphoramidite is a specialized chemical used in oligonucleotide synthesis for molecular biology and biotechnology applications. It is a type of phosphoramidite reagent designed to incorporate the Quasar 670 fluorescent dye into synthetic oligonucleotides. This dye is part of the Quasar series of fluorescent dyes, known for their high brightness and photostability. Quasar 670 Phosphoramidite enables the synthesis of labeled oligonucleotides for various applications such as fluorescence in situ hybridization (FISH), real-time PCR, and nucleic acid detection assays. Its incorporation allows researchers to visualize and track nucleic acids in biological samples with high sensitivity and specificity.

CAT: BRP-00478

MF: C48H69F6N5O3P2

MF: 940.05

Description: DusQ 1 phosphoramidite is a true dark quencher with broad absorption curve which covers the visible spectrum with maximum in green to yellow region. It is used for the synthesis of dual labeled oligonucleotide probes for qPCR bearing 5'-quencher DusQ 1 and other FRET applications for multiplexing assays.

CAT: BRP-00479

CAS: 374591-94-3

MF: C55H63N8O8P

MF: 995.11

Purity: ≥95%

Appearance: Black Powder

Description: DusQ 2 is a dark quenched dye used in the synthesis of double-labeled oligonucleotide probes for qPCR with a 5' quench agent. This quencher is ideal for HEX, JOE, ROX, Cyanine5 and other dyes that have emission spectra in the orange and red parts of the spectrum.

CAT: BRP-00480

CAS: 374591-98-7

MF: C54H61N8O9P

MF: 997.09

Description: 5'-Amino-Modifier C3 PDA is a biomedical research reagent used for oligonucleotide and DNA modification. Its versatility is manifested in facilitating the linking of a variety of molecules, such as antibodies and fluorescent dyes, enabling diagnostic and therapeutic interventions.

CAT: BRP-00481

MF: C21H33N4O4P

MF: 436.49

Description: 5'-Amino-Modifier C6 PDA is a chemical reagent used in oligonucleotide synthesis for molecular biology and biotechnology applications. It is a modification reagent designed to introduce an amino group at the 5' end of synthetic oligonucleotides. This amino group enables further conjugation with various molecules, such as fluorescent dyes, biotin, or other chemical groups, allowing for labeling or functionalization of the oligonucleotides. The C6 designation refers to the presence of a carbon chain spacer (hexyl linker) between the amino group and the phosphate group of the oligonucleotide backbone. This modification is particularly useful for applications such as PCR, sequencing, hybridization assays, and probe-based detection methods.

CAT: BRP-00482

CAS: 1445745-26-5

MF: C24H39N4O4P

MF: 478.57

Appearance: Light-yellow oily matter

Description: Thiol-Modifier C3 S-S CE Phosphoramidite is a specialized reagent used in oligonucleotide synthesis for molecular biology applications. It introduces a thiol (-SH) group into synthetic oligonucleotides at the third carbon position (C3) from the 5' end, connected to a disulfide bridge for stability. This modification enables reversible conjugation reactions, facilitating various applications such as DNA-protein interactions, surface immobilization, and biosensor development.

CAT: BRP-00483

CAS: 1263065-01-5

MF: C36H49N2O5PS2

MF: 684.89

Appearance: Colourless oily matter

Description: Spacer phosphamides C3, C9, C12, and C18 are used to insert spacer arms in oligonucleotides, and these compounds can be added multiple times when longer spacer arms are needed.

CAT: BRP-00484

CAS: 158041-82-8

MF: C36H49N2O5P

MF: 620.77

Purity: ≥98%

Appearance: Colourless oily matter

Description: Spermine CE Phosphoramidite is used to produce oligospermine-oligonucleotide conjugate-zip Nucleic Acids (ZNA) Oligos, which are thought to use oligospermine to find and move along the oligonucleotide chain (scan). Until the probe complementary sequence is found. Oligospermine then stabilizes the formed double chains by reducing electrostatic repulsion, thereby significantly increasing the binding affinity. ZNA oligomers can be used for the following applications: multiplex PCR, AT-rich region PCR, RT qPCR, MicroRNA detection, improved SNP recognition, and antisense and antigenic effects. Spermine phosphorite is easy to use in oligonucleotide synthesis, can be added multiple times at the 3' or 5' end, and is easy to protect and separate. HPLC analysis of conjugates requires a high pH value to inhibit the ionization of spermine residues.

CAT: BRP-00485

CAS: 942054-48-0

MF: C56H73F12N6O9P

MF: 1233.19

Appearance: Colourless oily matter

Description: 5'-Ferrocene CE Phosphoramidite is an oligonucleotide synthesis reagent that adds the electromagnetic group ferrocene to the oligonucleotide chain for application in oligonucleotide labeling. The absorption wavelength of 5'-Ferrocene CE Phosphoramidite is 438 nm and the extinction coefficient is 230M-1 cm-1.

CAT: BRP-00486

MF: C26H40FeN3O3P

MF: 529.44

Appearance: Yellow solid

Description: rG (iPr-Pac) CE-Phosphoramidite is a specialized reagent utilized in oligonucleotide synthesis. It incorporates a guanosine (G) residue modified with a tert-butyldimethylsilyl (TBDMS) group at the 2'-position and an isopropyl-pacidamycin (iPr-Pac) group. The TBDMS group provides stability during chemical synthesis, while the iPr-Pac group enhances functionality. The CE designation indicates its compatibility with controlled-efficiency (CE) phosphoramidite chemistry, ensuring efficient incorporation during solid-phase synthesis. This reagent facilitates the production of modified RNA oligonucleotides with improved stability and functionality, suitable for various molecular biology and biotechnology applications, including RNA interference and gene expression studies.

CAT: BRP-00495

CAS: 689283-85-0

MF: C57H74N7O10PSi

MF: 1076.32

Description: Quasar 570 Amidite is a specialized reagent utilized in oligonucleotide synthesis. It contains a fluorescent dye molecule that emits light at a wavelength of 570 nanometers, enabling the labeling of nucleic acid sequences during synthesis. This allows for the detection and visualization of the synthesized oligonucleotides in various molecular biology and biotechnology applications, including DNA sequencing, PCR, and fluorescence in situ hybridization (FISH). The Quasar 570 Amidite facilitates the development of labeled probes and primers for sensitive and specific nucleic acid detection assays.

CAT: BRP-00507

CAS: 1207162-64-8

MF: C44H65F6N5O4P2

MF: 903.95

Appearance: Red solid

Description: Long trebler phosphoramidite is a highly branched or multifunctional phosphoramidite, potentially offering unique properties or applications in oligonucleotide chemistry.It likely plays a crucial role in the efficient and controlled synthesis of oligonucleotides for various research and biotechnological applications.

CAT: BRP-00509

CAS: 1516489-83-0

MF: C89H107N2O15P

MF: 1475.78

Purity: ≥95%

Description: The 5'-Hexynyl CE Phosphoramidite is a reagent used in oligonucleotide synthesis. It features a hexynyl group at the 5'-end and is compatible with controlled-efficiency phosphoramidite chemistry. This modification allows for further bioconjugation through click chemistry reactions, making it valuable for labeling, imaging, and bioconjugation studies.

CAT: BRP-00510

CAS: 1048985-37-0

MF: C15H27N2O2P

MF: 298.36

Purity: ≥95% by HPLC

Description: 2'-O-C16-rA(Bz)-Phosphoramidite is a specialized reagent utilized in oligonucleotide synthesis. It contains a 2'-O-C16-rA(Bz) modification, where a C16 alkyl chain is attached to the 2'-position of riboadenosine (rA) and a benzoyl (Bz) group is attached to the adenine base. This modification enhances stability and functionality. It facilitates the production of modified RNA oligonucleotides with improved properties, suitable for various molecular biology and biotechnology applications, including RNA interference and gene expression studies.

CAT: BRP-00512

CAS: 2382942-35-8

MF: C63H84N7O8P

MF: 1098.38

Purity: ≥95%

Description: 6-Bromohexyl Phosphoramidite is a specialized reagent utilized in oligonucleotide synthesis. It contains a 6-bromohexyl group attached to the phosphoramidite backbone. This modification allows for the introduction of a bromohexyl moiety into the oligonucleotide sequence, facilitating further functionalization or conjugation reactions. This reagent enables the synthesis of modified oligonucleotides with specific chemical properties, suitable for various molecular biology and biotechnology applications, including DNA/RNA labeling, cross-linking, and affinity purification.

CAT: BRP-00513

CAS: 956093-29-1

MF: C15H30BrN2O2P

MF: 381.29

Purity: ≥95%