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Phosphoramidites

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2'-Modified Phosphoramidites
(466/466) 2'-Phosphoramidites
(21/21) 3'-Modified Phosphoramidites
(186/186) 5'-Modified Phosphoramidites
(21/21) Arabino Phosphoramidites
(19/19) Base Protected Phosphoramidites (365/365) Dye Phosphoramidites
(53/53) Label Phosphoramidites
(82/82) Linker Phosphoramidites
(72/72) Other Phosphoramidites
(92/92) PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12) Reverse Phosphoramidites
(15/15) Spacer Phosphoramidites
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5'-POM-(E)-vinyl phosphonate-2'-O-Me-rC(Bz)-3'-CE-Phosphoramidite

Description: 5'-POM-(E)-vinyl phosphonate-2'-O-Me-rC(Bz)-3'-CE-Phosphoramidite is employed to introduce modified cytosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00561
MF: C39H57N5O13P2
MF: 865.85
Purity: ≥98%
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InChIKey: JCWBJBRNLLVLQY-ZUZGDNAQSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=CC(=NC2=O)NC(=O)C=3C=CC=CC3)C1OC)C=CP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)N(C(C)C)C(C)C
IUPAC Name: ((((E)-2-((2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-4-methoxytetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)
InChI: InChI=1S/C39H57N5O13P2/c1-26(2)44(27(3)4)58(53-22-15-20-40)57-31-29(19-23-59(49,54-24-51-35(46)38(5,6)7)55-25-52-36(47)39(8,9)10)56-34(32(31)50-11)43-21-18-30(42-37(43)48)41-33(45)28-16-13-12-14-17-28/h12-14,16-19,21,23,26-27,29,31-32,34H,15,22,24-25H2,1-11H3,(H,41,42,45,48)/b23-19+/t29-,31-,32-,34-,58?/m1/s1

5'-POM-(E)-vinyl phosphonate-2'-O-Me-rG(iBu)-3'-CE-Phosphoramidite

Description: 5'-POM-(E)-vinyl phosphonate-2'-O-Me-rG(iBu)-3'-CE-Phosphoramidite is employed to introduce modified guanine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA structural studies, aptamer development, and gene regulation research.
CAT: BRP-00562
MF: C37H59N7O13P2
MF: 871.86
Purity: ≥98%
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InChIKey: BVJBAQGYDLYVPP-OGBCVAHGSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1OC)C=CP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)N(C(C)C)C(C)C
IUPAC Name: ((((E)-2-((2R,3R,4R,5R)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)
InChI: InChI=1S/C37H59N7O13P2/c1-22(2)30(45)41-35-40-29-26(31(46)42-35)39-19-43(29)32-28(50-13)27(57-58(53-17-14-16-38)44(23(3)4)24(5)6)25(56-32)15-18-59(49,54-20-51-33(47)36(7,8)9)55-21-52-34(48)37(10,11)12/h15,18-19,22-25,27-28,32H,14,17,20-21H2,1-13H3,(H2,40,41,42,45,46)/b18-15+/t25-,27-,28-,32-,58?/m1/s1

5'-POM-(E)-vinyl phosphonate-2'-O-Me-6-Deamino-6-(m-benzenepropanoic acid methyl ester)-rA-3'-CE-Phosphoramidite

Description: 5'-POM-(E)-vinyl phosphonate-2'-O-Me-6-Deamino-6-(m-benzenepropanoic acid methyl ester)-rA-3'-CE-Phosphoramidite is employed to introduce modified adenine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00563
MF: C43H62N6O13P2
MF: 932.95
Purity: ≥98%
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InChIKey: RKTQEWDKWSBILL-UQDZCBPASA-N
IUPAC Name: ((((E)-2-((2R,3R,4R,5R)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-4-methoxy-5-(6-(3-(3-methoxy-3-oxopropyl)phenyl)-9H-purin-9-yl)tetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)
InChI: InChI=1S/C43H62N6O13P2/c1-28(2)49(29(3)4)63(58-21-14-20-44)62-36-32(19-22-64(53,59-26-56-40(51)42(5,6)7)60-27-57-41(52)43(8,9)10)61-39(37(36)55-12)48-25-47-35-34(45-24-46-38(35)48)31-16-13-15-30(23-31)17-18-33(50)54-11/h13,15-16,19,22-25,28-29,32,36-37,39H,14,17-18,21,26-27H2,1-12H3/b22-19+/t32-,36-,37-,39-,63?/m1/s1

DMTr-2'-O-Me-rA(Bz)-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rA(Bz)-3'-(D)-PSM-Phosphoramidite is employed to introduce modified adenosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as antisense technology, RNA interference (RNAi), and gene regulation research.
CAT: BRP-00564
CAS: 2379296-27-0
MF: C51H51N6O10PS
MF: 971.03
Purity: ≥98%
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InChIKey: GAVWOPVBQOSPKA-GPNGAECYSA-N
CanonicalSMILES: O=C(NC1=NC=NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(OP7OC(CS(=O)(=O)C=8C=CC=CC8)C9N7CCC9)C3OC)C=%10C=CC=CC%10
IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-methoxy-4-(((1R,3R,3aR)-3-((phenylsulfonyl)methyl)tetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
InChI: InChI=1S/C51H51N6O10PS/c1-61-38-25-21-36(22-26-38)51(35-16-9-5-10-17-35,37-23-27-39(62-2)28-24-37)64-30-42-45(67-68-57-29-13-20-41(57)43(66-68)31-69(59,60)40-18-11-6-12-19-40)46(63-3)50(65-42)56-33-54-44-47(52-32-53-48(44)56)55-49(58)34-14-7-4-8-15-34/h4-12,14-19,21-28,32-33,41-43,45-46,50H,13,20,29-31H2,1-3H3,(H,52,53,55,58)/t41-,42-,43+,45-,46-,50-,68+/m1/s1
Synonyms: (D)-PSM-MA-RP; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-3'-O-[(1R,3R,3aR)-tetrahydro-3-[(phenylsulfonyl)methyl]-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl]-

DMTr-2'-O-Me-rA(Bz)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rA(Bz)-3'-(L)-PSM-Phosphoramidite is employed to introduce modified adenosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as antisense technology, RNA interference (RNAi), and gene regulation research.
CAT: BRP-00565
CAS: 2379296-17-8
MF: C51H51N6O10PS
MF: 971.03
Purity: ≥98%
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InChIKey: GAVWOPVBQOSPKA-UKMMDQOKSA-N
CanonicalSMILES: O=C(NC1=NC=NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(OP7OC(CS(=O)(=O)C=8C=CC=CC8)C9N7CCC9)C3OC)C=%10C=CC=CC%10
IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-methoxy-4-(((1S,3S,3aS)-3-((phenylsulfonyl)methyl)tetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
InChI: InChI=1S/C51H51N6O10PS/c1-61-38-25-21-36(22-26-38)51(35-16-9-5-10-17-35,37-23-27-39(62-2)28-24-37)64-30-42-45(67-68-57-29-13-20-41(57)43(66-68)31-69(59,60)40-18-11-6-12-19-40)46(63-3)50(65-42)56-33-54-44-47(52-32-53-48(44)56)55-49(58)34-14-7-4-8-15-34/h4-12,14-19,21-28,32-33,41-43,45-46,50H,13,20,29-31H2,1-3H3,(H,52,53,55,58)/t41-,42+,43+,45+,46+,50+,68+/m0/s1
Synonyms: (L)-PSM-MA-RP; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-3'-O-[(1S,3S,3aS)-tetrahydro-3-[(phenylsulfonyl)methyl]-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl]-

DMTr-2'-O-Me-rG(iBu)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rG(iBu)-3'-(L)-PSM-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified guanosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as antisense technology, RNA interference (RNAi), and gene regulation research.
CAT: BRP-00566
MF: C48H53N6O11PS
MF: 953.02
Purity: ≥98%
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InChIKey: QCPFOYJTUFIVGR-JADAPZILSA-N
CanonicalSMILES: O=C1N=C(NC(=O)C(C)C)NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(OP7OC(CS(=O)(=O)C=8C=CC=CC8)C9N7CCC9)C3OC
IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-methoxy-4-(((1S,3S,3aS)-3-((phenylsulfonyl)methyl)tetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl)oxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
InChI: InChI=1S/C48H53N6O11PS/c1-30(2)44(55)51-47-50-43-40(45(56)52-47)49-29-53(43)46-42(61-5)41(65-66-54-26-12-17-37(54)39(64-66)28-67(57,58)36-15-10-7-11-16-36)38(63-46)27-62-48(31-13-8-6-9-14-31,32-18-22-34(59-3)23-19-32)33-20-24-35(60-4)25-21-33/h6-11,13-16,18-25,29-30,37-39,41-42,46H,12,17,26-28H2,1-5H3,(H2,50,51,52,55,56)/t37-,38+,39+,41+,42+,46+,66+/m0/s1

DMTr-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite is used in oligonucleotide synthesis. It is employed to introduce modified uridine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as antisense technology, RNA interference (RNAi), and gene regulation research.
CAT: BRP-00567
CAS: 2963598-67-4
MF: C43H46N3O11PS
MF: 843.88
Purity: ≥98%
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InChIKey: WALZCFCZIWHBMO-NRIQKVBLSA-N
CanonicalSMILES: O=C1C=CN(C(=O)N1)C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(OP6OC(CS(=O)(=O)C=7C=CC=CC7)C8N6CCC8)C2OC
IUPAC Name: 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-methoxy-4-(((1S,3S,3aS)-3-((phenylsulfonyl)methyl)tetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl)oxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChI: InChI=1S/C43H46N3O11PS/c1-51-32-20-16-30(17-21-32)43(29-11-6-4-7-12-29,31-18-22-33(52-2)23-19-31)54-27-36-39(40(53-3)41(55-36)45-26-24-38(47)44-42(45)48)57-58-46-25-10-15-35(46)37(56-58)28-59(49,50)34-13-8-5-9-14-34/h4-9,11-14,16-24,26,35-37,39-41H,10,15,25,27-28H2,1-3H3,(H,44,47,48)/t35-,36+,37+,39+,40+,41+,58+/m0/s1
Synonyms: (L)-PSM-mU-Sp

DMTr-2'-O-Me-rC(Ac)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rC(Ac)-3'-(L)-PSM-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified cytidine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as antisense technology, RNA interference (RNAi), and gene regulation research.
CAT: BRP-00568
MF: C45H49N4O11PS
MF: 884.94
Purity: ≥98%
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InChIKey: AOAKYUMILRMJOU-KNYXQZDESA-N
IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-methoxy-4-(((1S,3S,3aS)-3-((phenylsulfonyl)methyl)tetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl)oxy)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
InChI: InChI=1S/C45H49N4O11PS/c1-30(50)46-40-25-27-48(44(51)47-40)43-42(56-4)41(60-61-49-26-11-16-37(49)39(59-61)29-62(52,53)36-14-9-6-10-15-36)38(58-43)28-57-45(31-12-7-5-8-13-31,32-17-21-34(54-2)22-18-32)33-19-23-35(55-3)24-20-33/h5-10,12-15,17-25,27,37-39,41-43H,11,16,26,28-29H2,1-4H3,(H,46,47,50,51)/t37-,38+,39+,41+,42+,43+,61+/m0/s1

DMTr-2'-O-Me-6-Deamino-6-(m-benzenepropanoic acid methyl ester)-rA-3'-CE-Phosphoramidite

Description: DMTr-2'-O-Me-6-Deamino-6-(m-benzenepropanoic acid methyl ester)-rA-3'-CE-Phosphoramidite is used in oligonucleotide synthesis. It is employed to introduce modified adenine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00569
MF: C51H59N6O9P
MF: 931.04
Purity: ≥98%
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InChIKey: UYFASKQCDQCXQQ-MREAKBAOSA-N
IUPAC Name: methyl 3-(3-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)phenyl)propanoate
InChI: InChI=1S/C51H59N6O9P/c1-34(2)57(35(3)4)67(64-29-13-28-52)66-47-43(31-63-51(38-16-10-9-11-17-38,39-19-23-41(59-5)24-20-39)40-21-25-42(60-6)26-22-40)65-50(48(47)62-8)56-33-55-46-45(53-32-54-49(46)56)37-15-12-14-36(30-37)18-27-44(58)61-7/h9-12,14-17,19-26,30,32-35,43,47-48,50H,13,18,27,29,31H2,1-8H3/t43-,47-,48-,50-,67?/m1/s1

DMTr-2'-O-Me-N2,N6-Diibu-2-amido-rA-3'-CE-Phosphoramidite

Description: DMTr-2'-O-Me-N2,N6-Diibu-2-amido-rA-3'-CE-Phosphoramidite is used in oligonucleotide synthesis. It is employed to introduce modified adenine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00570
CAS: 160526-51-2
MF: C49H63N8O9P
MF: 939.06
Purity: ≥98%
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InChIKey: GBCWEEZHQVKVPU-FKYZNXHZSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=NC(=NC32)NC(=O)C(C)C)NC(=O)C(C)C)C1OC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,6-diisobutyramido-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C49H63N8O9P/c1-30(2)45(58)52-43-40-44(54-48(53-43)55-46(59)31(3)4)56(29-51-40)47-42(62-11)41(66-67(64-27-15-26-50)57(32(5)6)33(7)8)39(65-47)28-63-49(34-16-13-12-14-17-34,35-18-22-37(60-9)23-19-35)36-20-24-38(61-10)25-21-36/h12-14,16-25,29-33,39,41-42,47H,15,27-28H2,1-11H3,(H2,52,53,54,55,58,59)/t39-,41-,42-,47-,67?/m1/s1
Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-2-[(2-methyl-1-oxopropyl)amino]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-2-[(2-methyl-1-oxopropyl)amino]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

5'-POM-(E)-vinyl phosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite

Description: 5'-POM-(E)-vinyl phosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite is used in oligonucleotide synthesis. It is employed to introduce modified adenine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00571
CAS: 2419895-65-9
MF: C40H57N7O12P2
MF: 889.88
Purity: ≥98%
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InChIKey: DCUPCJOKPAHCLB-OZKJWBRJSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=NC=NC32)NC(=O)C=4C=CC=CC4)C1OC)C=CP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)N(C(C)C)C(C)C
IUPAC Name: ((((E)-2-((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-4-methoxytetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)
InChI: InChI=1S/C40H57N7O12P2/c1-26(2)47(27(3)4)60(55-20-15-19-41)59-31-29(18-21-61(51,56-24-53-37(49)39(5,6)7)57-25-54-38(50)40(8,9)10)58-36(32(31)52-11)46-23-44-30-33(42-22-43-34(30)46)45-35(48)28-16-13-12-14-17-28/h12-14,16-18,21-23,26-27,29,31-32,36H,15,20,24-25H2,1-11H3,(H,42,43,45,48)/b21-18+/t29-,31-,32-,36-,60?/m1/s1
Synonyms: Benzamide, N-[9-[(5E)-6-[bis[(2,2-dimethyl-1-oxopropoxy)methoxy]phosphinyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5,6-dideoxy-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]-9H-purin-6-yl]-; VP-2'-OMe-A(Bz)-CE-Phosphoramidite; vinyl phosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite

DMTr-2'-O-MOE-rC(Ac)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-rC(Ac)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified cytidine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00572
MF: C44H56N5O10P
MF: 845.93
Purity: ≥98%
Appearance: White to off-white powder
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InChIKey: VSHRWOKGZWQVKY-FSEQMNGPSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C44H56N5O10P/c1-30(2)49(31(3)4)60(57-26-12-24-45)59-40-38(58-42(41(40)55-28-27-52-6)48-25-23-39(46-32(5)50)47-43(48)51)29-56-44(33-13-10-9-11-14-33,34-15-19-36(53-7)20-16-34)35-17-21-37(54-8)22-18-35/h9-11,13-23,25,30-31,38,40-42H,12,26-29H2,1-8H3,(H,46,47,50,51)/t38-,40-,41-,42-,60?/m1/s1
Synonyms: 5'-O-DMT-N4-Acetyl-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite; Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

DMTr-2'-O-MOE-rG(dmf)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-rG(dmf)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified guanosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00573
MF: C46H59N8O9P
MF: 898.98
Purity: ≥98%
Appearance: Off-white solid
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Storage: Store at -20 °C
InChIKey: IHRMKEYMVRZIQH-PFKWAGDCSA-N
Solubility: Soluble in Acetonitrile, DMF
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-(((dimethylamino)methylene)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C46H59N8O9P/c1-31(2)54(32(3)4)64(61-25-13-24-47)63-40-38(62-44(41(40)59-27-26-56-7)53-30-48-39-42(53)50-45(51-43(39)55)49-29-52(5)6)28-60-46(33-14-11-10-12-15-33,34-16-20-36(57-8)21-17-34)35-18-22-37(58-9)23-19-35/h10-12,14-23,29-32,38,40-41,44H,13,25-28H2,1-9H3,(H,50,51,55)/t38-,40-,41-,44-,64?/m1/s1
Synonyms: 5'-O-DMT-2'-O-MOE-G(dmf)-CE Phosphoramidite; 2'-MOE G(dmf) amidite; DMT-2'-O-MOE-G(dmf)-CE-Phosphoramidite; N2-Dimethylformamidine-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-guanosine-3'-cyanoethyl Phosphoramidite

DMTr-2'-O-MOE-5-Me-rC-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-5-Me-rC-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified cytidine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00574
CAS: 251647-56-0
MF: C43H56N5O9P
MF: 817.92
Purity: ≥90%
Appearance: White to off-white powder
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Storage: Store at -20 °C
InChIKey: FGTJXCRQSYSIEF-KZQAAKLLSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=C(C(=NC2=O)N)C)C1OCCOC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C43H56N5O9P/c1-29(2)48(30(3)4)58(55-24-12-23-44)57-38-37(56-41(39(38)53-26-25-50-6)47-27-31(5)40(45)46-42(47)49)28-54-43(32-13-10-9-11-14-32,33-15-19-35(51-7)20-16-33)34-17-21-36(52-8)22-18-34/h9-11,13-22,27,29-30,37-39,41H,12,24-26,28H2,1-8H3,(H2,45,46,49)/t37-,38-,39-,41-,58?/m1/s1
Synonyms: Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 5-Me-5'-O-DMT-2'-O-MOE-Cr 3'-CE-Phosphoramidite; 5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine-3'-cyanoethyl Phosphoramidite

DMTr-2'-O-MOE-5-Me-rC(DMTr)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-5-Me-rC(DMTr)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified cytidine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00575
MF: C64H74N5O11P
MF: 1120.29
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: NHLNZHFBOBWWBL-XCWYBNAASA-N
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-((bis(4-methoxyphenyl)(phenyl)methyl)amino)-5-methyl-2-oxopyrimidin-1(2H)-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C64H74N5O11P/c1-44(2)69(45(3)4)81(78-39-17-38-65)80-58-57(43-77-64(50-20-15-12-16-21-50,51-26-34-55(74-9)35-27-51)52-28-36-56(75-10)37-29-52)79-61(59(58)76-41-40-71-6)68-42-46(5)60(66-62(68)70)67-63(47-18-13-11-14-19-47,48-22-30-53(72-7)31-23-48)49-24-32-54(73-8)33-25-49/h11-16,18-37,42,44-45,57-59,61H,17,39-41,43H2,1-10H3,(H,66,67,70)/t57-,58-,59-,61-,81?/m1/s1

DMTr-2'-O-MOE-rG-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-rG-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified guanosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00576
CAS: 1558023-79-2
MF: C43H54N7O9P
MF: 843.91
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: BONZQXQXGMLHEM-USUFPPIWSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(N)NC32)C1OCCOC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: (2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C43H54N7O9P/c1-28(2)50(29(3)4)60(57-23-11-22-44)59-37-35(58-41(38(37)55-25-24-52-5)49-27-46-36-39(49)47-42(45)48-40(36)51)26-56-43(30-12-9-8-10-13-30,31-14-18-33(53-6)19-15-31)32-16-20-34(54-7)21-17-32/h8-10,12-21,27-29,35,37-38,41H,11,23-26H2,1-7H3,(H3,45,47,48,51)/t35-,37-,38-,41-,60?/m1/s1
Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)guanosine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite); Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

DMTr-2'-O-MOE-rG(DMTr)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-rG(DMTr)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified guanosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00577
MF: C64H72N7O11P
MF: 1146.29
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: RBJNKLVMRRLXHA-IDILFZDASA-N
IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-((bis(4-methoxyphenyl)(phenyl)methyl)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C64H72N7O11P/c1-43(2)71(44(3)4)83(80-38-16-37-65)82-57-55(41-79-64(48-19-14-11-15-20-48,49-25-33-53(76-8)34-26-49)50-27-35-54(77-9)36-28-50)81-61(58(57)78-40-39-73-5)70-42-66-56-59(70)67-62(68-60(56)72)69-63(45-17-12-10-13-18-45,46-21-29-51(74-6)30-22-46)47-23-31-52(75-7)32-24-47/h10-15,17-36,42-44,55,57-58,61H,16,38-41H2,1-9H3,(H2,67,68,69,72)/t55-,57-,58-,61-,83?/m1/s1

DMTr-2'-O-MOE-rA-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-rA-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified adenosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00578
CAS: 1558023-78-1
MF: C43H54N7O8P
MF: 827.91
Purity: ≥95% by HPLC
Appearance: White, off-white to faint yellow powder
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Storage: Store at -20 °C
InChIKey: SMHLYNOCXUPBAV-NFQMNAKDSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=NC=NC32)N)C1OCCOC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C
IUPAC Name: 3-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-(2-methoxyethoxy)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C43H54N7O8P/c1-29(2)50(30(3)4)59(56-23-11-22-44)58-38-36(57-42(39(38)54-25-24-51-5)49-28-48-37-40(45)46-27-47-41(37)49)26-55-43(31-12-9-8-10-13-31,32-14-18-34(52-6)19-15-32)33-16-20-35(53-7)21-17-33/h8-10,12-21,27-30,36,38-39,42H,11,23-26H2,1-7H3,(H2,45,46,47)/t36-,38-,39-,42-,59?/m1/s1
Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)adenosine 3'-O-(2-cyanoethyl N,N-diisopropylphosphoramidite); Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; DMT-2'-O-MOE-Ar-CE-Phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl Phosphoramidite

DMTr-2'-O-MOE-rA(Bz)-3'-CE-(1-hydroxy-N,N-diisopropyl)phosphoramidite

Description: DMTr-2'-O-MOE-rA(Bz)-3'-CE-(1-hydroxy-N,N-diisopropyl)phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified adenosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00579
MF: C47H55N6O9P
MF: 878.96
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: QDIFFXPFBYESPR-QCDZHEALSA-N
IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl hydrogen diisopropylphosphoramidite
InChI: InChI=1S/C47H55N6O9P/c1-31(2)53(32(3)4)63(55)62-41-39(28-60-47(34-16-12-9-13-17-34,35-18-22-37(57-6)23-19-35)36-20-24-38(58-7)25-21-36)61-46(42(41)59-27-26-56-5)52-30-50-40-43(48-29-49-44(40)52)51-45(54)33-14-10-8-11-15-33/h8-25,29-32,39,41-42,46,55H,26-28H2,1-7H3,(H,48,49,51,54)/t39-,41-,42-,46-,63?/m1/s1

DMTr-2'-O-MOE-rA(DMTr)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-rA(DMTr)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified adenosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.
CAT: BRP-00580
MF: C64H72N7O10P
MF: 1130.29
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: IOSMJVNZGCZZRX-LEYRIAGYSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OCCOC)N2C=NC3=C(N=CN=C32)NC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)COC(C7=CC=CC=C7)(C8=CC=C(C=C8)OC)C9=CC=C(C=C9)OC
IUPAC Name: 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-[6-[[bis(4-methoxyphenyl)-phenylmethyl]amino]purin-9-yl]-4-(2-methoxyethoxy)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C64H72N7O10P/c1-44(2)71(45(3)4)82(79-38-16-37-65)81-58-56(41-78-64(49-19-14-11-15-20-49,50-25-33-54(75-8)34-26-50)51-27-35-55(76-9)36-28-51)80-62(59(58)77-40-39-72-5)70-43-68-57-60(66-42-67-61(57)70)69-63(46-17-12-10-13-18-46,47-21-29-52(73-6)30-22-47)48-23-31-53(74-7)32-24-48/h10-15,17-36,42-45,56,58-59,62H,16,38-41H2,1-9H3,(H,66,67,69)/t56-,58-,59-,62-,82?/m1/s1
Synonyms: (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-((bis(4-methoxyphenyl)(phenyl)methyl)amino)-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
* Only for research. Not suitable for any diagnostic or therapeutic use.

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