Phosphoramidites - RNA / BOC Sciences

DMTr-2'-O-TBDMS-5-OMe-rU-3'-CE-Phosphoramidite

Description: DMTr-2'-O-TBDMS-5-OMe-rU-3'-CE-Phosphoramidite is employed in oligonucleotide synthesis and features a TBDMS (tert-butyldimethylsilyl) group at the 2'-O position, and a methoxy (OMe) group on the uracil (rU) nucleoside. The 3'-end is functionalized with a cyanoethyl (CE) group, facilitating efficient coupling reactions during solid-phase synthesis. It is used to introduce modified uracil residues with increased stability and altered base pairing properties into nucleic acid sequences, suitable for various research applications including RNA structural studies, aptamer development, and gene regulation research.

CAT: BRP-00560

Molecular Formula: C46H63N4O10PSi

Molecular Weight: 891.09

Purity: ≥98%

Appearance: White, off-white to faint yellow powder

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InChIKey: OWTUZLAYUDYRNE-ACYYXZCMSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=C(C(=O)NC2=O)OC)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: 3-[[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-(5-methoxy-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C46H63N4O10PSi/c1-31(2)50(32(3)4)61(57-28-16-27-47)59-40-39(58-43(41(40)60-62(11,12)45(5,6)7)49-29-38(55-10)42(51)48-44(49)52)30-56-46(33-17-14-13-15-18-33,34-19-23-36(53-8)24-20-34)35-21-25-37(54-9)26-22-35/h13-15,17-26,29,31-32,39-41,43H,16,28,30H2,1-12H3,(H,48,51,52)/t39-,40-,41-,43-,61?/m1/s1

Synonyms: 5'-O-DMTr-2'-O-TBDMS-5-methoxyuridine-3'-(cyanoethyl-N,N-diisopropyl)phosphoramidite; (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(5-methoxy-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-2'-O-TBDMS-5-OMe-Ur Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-5-O-methyl-Uridine 3'-cyanoethyl Phosphoramidite

5'-POM-(E)-vinyl phosphonate-2'-O-Me-rC(Bz)-3'-CE-Phosphoramidite

Description: 5'-POM-(E)-vinyl phosphonate-2'-O-Me-rC(Bz)-3'-CE-Phosphoramidite is employed to introduce modified cytosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00561

Molecular Formula: C39H57N5O13P2

Molecular Weight: 865.85

Purity: ≥98%

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InChIKey: JCWBJBRNLLVLQY-ZUZGDNAQSA-N

CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=CC(=NC2=O)NC(=O)C=3C=CC=CC3)C1OC)C=CP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)N(C(C)C)C(C)C

IUPAC Name: ((((E)-2-((2R,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-4-methoxytetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)

InChI: InChI=1S/C39H57N5O13P2/c1-26(2)44(27(3)4)58(53-22-15-20-40)57-31-29(19-23-59(49,54-24-51-35(46)38(5,6)7)55-25-52-36(47)39(8,9)10)56-34(32(31)50-11)43-21-18-30(42-37(43)48)41-33(45)28-16-13-12-14-17-28/h12-14,16-19,21,23,26-27,29,31-32,34H,15,22,24-25H2,1-11H3,(H,41,42,45,48)/b23-19+/t29-,31-,32-,34-,58?/m1/s1

5'-POM-(E)-vinyl phosphonate-2'-O-Me-rG(iBu)-3'-CE-Phosphoramidite

Description: 5'-POM-(E)-vinyl phosphonate-2'-O-Me-rG(iBu)-3'-CE-Phosphoramidite is employed to introduce modified guanine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA structural studies, aptamer development, and gene regulation research.

CAT: BRP-00562

Molecular Formula: C37H59N7O13P2

Molecular Weight: 871.86

Purity: ≥98%

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InChIKey: BVJBAQGYDLYVPP-OGBCVAHGSA-N

CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1OC)C=CP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)N(C(C)C)C(C)C

IUPAC Name: ((((E)-2-((2R,3R,4R,5R)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)

InChI: InChI=1S/C37H59N7O13P2/c1-22(2)30(45)41-35-40-29-26(31(46)42-35)39-19-43(29)32-28(50-13)27(57-58(53-17-14-16-38)44(23(3)4)24(5)6)25(56-32)15-18-59(49,54-20-51-33(47)36(7,8)9)55-21-52-34(48)37(10,11)12/h15,18-19,22-25,27-28,32H,14,17,20-21H2,1-13H3,(H2,40,41,42,45,46)/b18-15+/t25-,27-,28-,32-,58?/m1/s1

Synonyms: 5'(E)-VP-2'-OMe-G(ibu)-CE-Phoshoramidite; 5'-POM-(E)-vinyl phosphonate-2'-O-Me-rG(iBu)-3'-CE-Phosphoramidite; 5'-(E)-VP-2'-OMe-G(iBu)-CE-Phoshoramidite

5'-POM-(E)-vinyl phosphonate-2'-O-Me-6-Deamino-6-(m-benzenepropanoic acid methyl ester)-rA-3'-CE-Phosphoramidite

Description: 5'-POM-(E)-vinyl phosphonate-2'-O-Me-6-Deamino-6-(m-benzenepropanoic acid methyl ester)-rA-3'-CE-Phosphoramidite is employed to introduce modified adenine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00563

Molecular Formula: C43H62N6O13P2

Molecular Weight: 932.95

Purity: ≥98%

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InChIKey: RKTQEWDKWSBILL-UQDZCBPASA-N

IUPAC Name: ((((E)-2-((2R,3R,4R,5R)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-4-methoxy-5-(6-(3-(3-methoxy-3-oxopropyl)phenyl)-9H-purin-9-yl)tetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)

InChI: InChI=1S/C43H62N6O13P2/c1-28(2)49(29(3)4)63(58-21-14-20-44)62-36-32(19-22-64(53,59-26-56-40(51)42(5,6)7)60-27-57-41(52)43(8,9)10)61-39(37(36)55-12)48-25-47-35-34(45-24-46-38(35)48)31-16-13-15-30(23-31)17-18-33(50)54-11/h13,15-16,19,22-25,28-29,32,36-37,39H,14,17-18,21,26-27H2,1-12H3/b22-19+/t32-,36-,37-,39-,63?/m1/s1

DMTr-2'-O-Me-rA(Bz)-3'-(D)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rA(Bz)-3'-(D)-PSM-Phosphoramidite is employed to introduce modified adenosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as antisense technology, RNA interference (RNAi), and gene regulation research.

CAT: BRP-00564

CAS: 2379296-27-0

Molecular Formula: C51H51N6O10PS

Molecular Weight: 971.03

Purity: ≥98%

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InChIKey: GAVWOPVBQOSPKA-GPNGAECYSA-N

CanonicalSMILES: O=C(NC1=NC=NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(OP7OC(CS(=O)(=O)C=8C=CC=CC8)C9N7CCC9)C3OC)C=%10C=CC=CC%10

IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-methoxy-4-(((1R,3R,3aR)-3-((phenylsulfonyl)methyl)tetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

InChI: InChI=1S/C51H51N6O10PS/c1-61-38-25-21-36(22-26-38)51(35-16-9-5-10-17-35,37-23-27-39(62-2)28-24-37)64-30-42-45(67-68-57-29-13-20-41(57)43(66-68)31-69(59,60)40-18-11-6-12-19-40)46(63-3)50(65-42)56-33-54-44-47(52-32-53-48(44)56)55-49(58)34-14-7-4-8-15-34/h4-12,14-19,21-28,32-33,41-43,45-46,50H,13,20,29-31H2,1-3H3,(H,52,53,55,58)/t41-,42-,43+,45-,46-,50-,68+/m1/s1

Synonyms: (D)-PSM-MA-RP; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-3'-O-[(1R,3R,3aR)-tetrahydro-3-[(phenylsulfonyl)methyl]-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl]-

DMTr-2'-O-Me-rA(Bz)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rA(Bz)-3'-(L)-PSM-Phosphoramidite is employed to introduce modified adenosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as antisense technology, RNA interference (RNAi), and gene regulation research.

CAT: BRP-00565

CAS: 2379296-17-8

Molecular Formula: C51H51N6O10PS

Molecular Weight: 971.03

Purity: ≥98%

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InChIKey: GAVWOPVBQOSPKA-UKMMDQOKSA-N

CanonicalSMILES: O=C(NC1=NC=NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(OP7OC(CS(=O)(=O)C=8C=CC=CC8)C9N7CCC9)C3OC)C=%10C=CC=CC%10

IUPAC Name: N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-methoxy-4-(((1S,3S,3aS)-3-((phenylsulfonyl)methyl)tetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide

Synonyms: (L)-PSM-MA-RP; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-3'-O-[(1S,3S,3aS)-tetrahydro-3-[(phenylsulfonyl)methyl]-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl]-

DMTr-2'-O-Me-rG(iBu)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rG(iBu)-3'-(L)-PSM-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified guanosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as antisense technology, RNA interference (RNAi), and gene regulation research.

CAT: BRP-00566

Molecular Formula: C48H53N6O11PS

Molecular Weight: 953.02

Purity: ≥98%

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InChIKey: QCPFOYJTUFIVGR-JADAPZILSA-N

CanonicalSMILES: O=C1N=C(NC(=O)C(C)C)NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(OP7OC(CS(=O)(=O)C=8C=CC=CC8)C9N7CCC9)C3OC

InChI: InChI=1S/C48H53N6O11PS/c1-30(2)44(55)51-47-50-43-40(45(56)52-47)49-29-53(43)46-42(61-5)41(65-66-54-26-12-17-37(54)39(64-66)28-67(57,58)36-15-10-7-11-16-36)38(63-46)27-62-48(31-13-8-6-9-14-31,32-18-22-34(59-3)23-19-32)33-20-24-35(60-4)25-21-33/h6-11,13-16,18-25,29-30,37-39,41-42,46H,12,17,26-28H2,1-5H3,(H2,50,51,52,55,56)/t37-,38+,39+,41+,42+,46+,66+/m0/s1

DMTr-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rU-3'-(L)-PSM-Phosphoramidite is used in oligonucleotide synthesis. It is employed to introduce modified uridine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as antisense technology, RNA interference (RNAi), and gene regulation research.

CAT: BRP-00567

CAS: 2963598-67-4

Molecular Formula: C43H46N3O11PS

Molecular Weight: 843.88

Purity: ≥98%

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InChIKey: WALZCFCZIWHBMO-NRIQKVBLSA-N

CanonicalSMILES: O=C1C=CN(C(=O)N1)C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(OP6OC(CS(=O)(=O)C=7C=CC=CC7)C8N6CCC8)C2OC

IUPAC Name: 1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-methoxy-4-(((1S,3S,3aS)-3-((phenylsulfonyl)methyl)tetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl)oxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

InChI: InChI=1S/C43H46N3O11PS/c1-51-32-20-16-30(17-21-32)43(29-11-6-4-7-12-29,31-18-22-33(52-2)23-19-31)54-27-36-39(40(53-3)41(55-36)45-26-24-38(47)44-42(45)48)57-58-46-25-10-15-35(46)37(56-58)28-59(49,50)34-13-8-5-9-14-34/h4-9,11-14,16-24,26,35-37,39-41H,10,15,25,27-28H2,1-3H3,(H,44,47,48)/t35-,36+,37+,39+,40+,41+,58+/m0/s1

Synonyms: (L)-PSM-mU-Sp

DMTr-2'-O-Me-rC(Ac)-3'-(L)-PSM-Phosphoramidite

Description: DMTr-2'-O-Me-rC(Ac)-3'-(L)-PSM-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified cytidine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as antisense technology, RNA interference (RNAi), and gene regulation research.

CAT: BRP-00568

Molecular Formula: C45H49N4O11PS

Molecular Weight: 884.94

Purity: ≥98%

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InChIKey: AOAKYUMILRMJOU-KNYXQZDESA-N

IUPAC Name: N-(1-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-methoxy-4-(((1S,3S,3aS)-3-((phenylsulfonyl)methyl)tetrahydro-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaphosphol-1-yl)oxy)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide

InChI: InChI=1S/C45H49N4O11PS/c1-30(50)46-40-25-27-48(44(51)47-40)43-42(56-4)41(60-61-49-26-11-16-37(49)39(59-61)29-62(52,53)36-14-9-6-10-15-36)38(58-43)28-57-45(31-12-7-5-8-13-31,32-17-21-34(54-2)22-18-32)33-19-23-35(55-3)24-20-33/h5-10,12-15,17-25,27,37-39,41-43H,11,16,26,28-29H2,1-4H3,(H,46,47,50,51)/t37-,38+,39+,41+,42+,43+,61+/m0/s1

DMTr-2'-O-Me-6-Deamino-6-(m-benzenepropanoic acid methyl ester)-rA-3'-CE-Phosphoramidite

Description: DMTr-2'-O-Me-6-Deamino-6-(m-benzenepropanoic acid methyl ester)-rA-3'-CE-Phosphoramidite is used in oligonucleotide synthesis. It is employed to introduce modified adenine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00569

Molecular Formula: C51H59N6O9P

Molecular Weight: 931.04

Purity: ≥98%

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InChIKey: UYFASKQCDQCXQQ-MREAKBAOSA-N

IUPAC Name: methyl 3-(3-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-yl)phenyl)propanoate

InChI: InChI=1S/C51H59N6O9P/c1-34(2)57(35(3)4)67(64-29-13-28-52)66-47-43(31-63-51(38-16-10-9-11-17-38,39-19-23-41(59-5)24-20-39)40-21-25-42(60-6)26-22-40)65-50(48(47)62-8)56-33-55-46-45(53-32-54-49(46)56)37-15-12-14-36(30-37)18-27-44(58)61-7/h9-12,14-17,19-26,30,32-35,43,47-48,50H,13,18,27,29,31H2,1-8H3/t43-,47-,48-,50-,67?/m1/s1

DMTr-2'-O-Me-N2,N6-Diibu-2-amido-rA-3'-CE-Phosphoramidite

Description: DMTr-2'-O-Me-N2,N6-Diibu-2-amido-rA-3'-CE-Phosphoramidite is used in oligonucleotide synthesis. It is employed to introduce modified adenine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00570

CAS: 160526-51-2

Molecular Formula: C49H63N8O9P

Molecular Weight: 939.06

Purity: ≥98%

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InChIKey: GBCWEEZHQVKVPU-FKYZNXHZSA-N

CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=NC(=NC32)NC(=O)C(C)C)NC(=O)C(C)C)C1OC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,6-diisobutyramido-9H-purin-9-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C49H63N8O9P/c1-30(2)45(58)52-43-40-44(54-48(53-43)55-46(59)31(3)4)56(29-51-40)47-42(62-11)41(66-67(64-27-15-26-50)57(32(5)6)33(7)8)39(65-47)28-63-49(34-16-13-12-14-17-34,35-18-22-37(60-9)23-19-35)36-20-24-38(61-10)25-21-36/h12-14,16-25,29-33,39,41-42,47H,15,27-28H2,1-11H3,(H2,52,53,54,55,58,59)/t39-,41-,42-,47-,67?/m1/s1

Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-2-[(2-methyl-1-oxopropyl)amino]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-N-(2-methyl-1-oxopropyl)-2-[(2-methyl-1-oxopropyl)amino]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

5'-POM-(E)-vinyl phosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite

Description: 5'-POM-(E)-vinyl phosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite is used in oligonucleotide synthesis. It is employed to introduce modified adenine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00571

CAS: 2419895-65-9

Molecular Formula: C40H57N7O12P2

Molecular Weight: 889.88

Purity: ≥98%

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InChIKey: DCUPCJOKPAHCLB-OZKJWBRJSA-N

CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=NC=NC32)NC(=O)C=4C=CC=CC4)C1OC)C=CP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)N(C(C)C)C(C)C

IUPAC Name: ((((E)-2-((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-4-methoxytetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)

InChI: InChI=1S/C40H57N7O12P2/c1-26(2)47(27(3)4)60(55-20-15-19-41)59-31-29(18-21-61(51,56-24-53-37(49)39(5,6)7)57-25-54-38(50)40(8,9)10)58-36(32(31)52-11)46-23-44-30-33(42-22-43-34(30)46)45-35(48)28-16-13-12-14-17-28/h12-14,16-18,21-23,26-27,29,31-32,36H,15,20,24-25H2,1-11H3,(H,42,43,45,48)/b21-18+/t29-,31-,32-,36-,60?/m1/s1

Synonyms: N-[9-[(5E)-6-[Bis[(2,2-dimethyl-1-oxopropoxy)methoxy]phosphinyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5,6-dideoxy-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]-9H-purin-6-yl]benzamide; (E)-VP-2'-OMe-A(Bz)-CE-Phosphoramidite; (E)-Vinyl phosphonate-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite; 5'-VP-2'-0Me-A(Bz)-CE-Phosphoramidite; (E)-5'-VP-2'-0Me-A(Bz)-CE-Phosphoramidite

DMTr-2'-O-MOE-rC(Ac)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-rC(Ac)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified cytidine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00572

Molecular Formula: C44H56N5O10P

Molecular Weight: 845.93

Purity: ≥98%

Appearance: White to off-white powder

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InChIKey: VSHRWOKGZWQVKY-FSEQMNGPSA-N

IUPAC Name: (2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C44H56N5O10P/c1-30(2)49(31(3)4)60(57-26-12-24-45)59-40-38(58-42(41(40)55-28-27-52-6)48-25-23-39(46-32(5)50)47-43(48)51)29-56-44(33-13-10-9-11-14-33,34-15-19-36(53-7)20-16-34)35-17-21-37(54-8)22-18-35/h9-11,13-23,25,30-31,38,40-42H,12,26-29H2,1-8H3,(H,46,47,50,51)/t38-,40-,41-,42-,60?/m1/s1

Synonyms: 5'-O-DMT-N4-Acetyl-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite; Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

DMTr-2'-O-MOE-rG(dmf)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-rG(dmf)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified guanosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00573

Molecular Formula: C46H59N8O9P

Molecular Weight: 898.98

Purity: ≥98%

Appearance: Off-white solid

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InChIKey: IHRMKEYMVRZIQH-PFKWAGDCSA-N

Solubility: Soluble in Acetonitrile, DMF

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-(((dimethylamino)methylene)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C46H59N8O9P/c1-31(2)54(32(3)4)64(61-25-13-24-47)63-40-38(62-44(41(40)59-27-26-56-7)53-30-48-39-42(53)50-45(51-43(39)55)49-29-52(5)6)28-60-46(33-14-11-10-12-15-33,34-16-20-36(57-8)21-17-34)35-18-22-37(58-9)23-19-35/h10-12,14-23,29-32,38,40-41,44H,13,25-28H2,1-9H3,(H,50,51,55)/t38-,40-,41-,44-,64?/m1/s1

Synonyms: 5'-O-DMT-2'-O-MOE-G(dmf)-CE Phosphoramidite; 2'-MOE G(dmf) amidite; DMT-2'-O-MOE-G(dmf)-CE-Phosphoramidite; N2-Dimethylformamidine-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-guanosine-3'-cyanoethyl Phosphoramidite

DMTr-2'-O-MOE-5-Me-rC-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-5-Me-rC-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified cytidine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00574

CAS: 251647-56-0

Molecular Formula: C43H56N5O9P

Molecular Weight: 817.92

Purity: ≥90%

Appearance: White to off-white powder

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InChIKey: FGTJXCRQSYSIEF-KZQAAKLLSA-N

CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=C(C(=NC2=O)N)C)C1OCCOC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C

IUPAC Name: (2R,3R,4R,5R)-5-(4-amino-5-methyl-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C43H56N5O9P/c1-29(2)48(30(3)4)58(55-24-12-23-44)57-38-37(56-41(39(38)53-26-25-50-6)47-27-31(5)40(45)46-42(47)49)28-54-43(32-13-10-9-11-14-32,33-15-19-35(51-7)20-16-33)34-17-21-36(52-8)22-18-34/h9-11,13-22,27,29-30,37-39,41H,12,24-26,28H2,1-8H3,(H2,45,46,49)/t37-,38-,39-,41-,58?/m1/s1

Synonyms: Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-5-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 5-Me-5'-O-DMT-2'-O-MOE-Cr 3'-CE-Phosphoramidite; 5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine-3'-cyanoethyl Phosphoramidite

DMTr-2'-O-MOE-5-Me-rC(DMTr)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-5-Me-rC(DMTr)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified cytidine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00575

Molecular Formula: C64H74N5O11P

Molecular Weight: 1120.29

Purity: ≥98%

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InChIKey: NHLNZHFBOBWWBL-XCWYBNAASA-N

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-((bis(4-methoxyphenyl)(phenyl)methyl)amino)-5-methyl-2-oxopyrimidin-1(2H)-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C64H74N5O11P/c1-44(2)69(45(3)4)81(78-39-17-38-65)80-58-57(43-77-64(50-20-15-12-16-21-50,51-26-34-55(74-9)35-27-51)52-28-36-56(75-10)37-29-52)79-61(59(58)76-41-40-71-6)68-42-46(5)60(66-62(68)70)67-63(47-18-13-11-14-19-47,48-22-30-53(72-7)31-23-48)49-24-32-54(73-8)33-25-49/h11-16,18-37,42,44-45,57-59,61H,17,39-41,43H2,1-10H3,(H,66,67,70)/t57-,58-,59-,61-,81?/m1/s1

DMTr-2'-O-MOE-rG-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-rG-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified guanosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00576

CAS: 1558023-79-2

Molecular Formula: C43H54N7O9P

Molecular Weight: 843.91

Purity: ≥98%

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InChIKey: BONZQXQXGMLHEM-USUFPPIWSA-N

CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(N)NC32)C1OCCOC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C

IUPAC Name: (2R,3R,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C43H54N7O9P/c1-28(2)50(29(3)4)60(57-23-11-22-44)59-37-35(58-41(38(37)55-25-24-52-5)49-27-46-36-39(49)47-42(45)48-40(36)51)26-56-43(30-12-9-8-10-13-30,31-14-18-33(53-6)19-15-31)32-16-20-34(54-7)21-17-32/h8-10,12-21,27-29,35,37-38,41H,11,23-26H2,1-7H3,(H3,45,47,48,51)/t35-,37-,38-,41-,60?/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)guanosine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite); Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

DMTr-2'-O-MOE-rG(DMTr)-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-rG(DMTr)-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified guanosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00577

Molecular Formula: C64H72N7O11P

Molecular Weight: 1146.29

Purity: ≥95%

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InChIKey: RBJNKLVMRRLXHA-IDILFZDASA-N

IUPAC Name: (2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-((bis(4-methoxyphenyl)(phenyl)methyl)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C64H72N7O11P/c1-43(2)71(44(3)4)83(80-38-16-37-65)82-57-55(41-79-64(48-19-14-11-15-20-48,49-25-33-53(76-8)34-26-49)50-27-35-54(77-9)36-28-50)81-61(58(57)78-40-39-73-5)70-42-66-56-59(70)67-62(68-60(56)72)69-63(45-17-12-10-13-18-45,46-21-29-51(74-6)30-22-46)47-23-31-52(75-7)32-24-47/h10-15,17-36,42-44,55,57-58,61H,16,38-41H2,1-9H3,(H2,67,68,69,72)/t55-,57-,58-,61-,83?/m1/s1

DMTr-2'-O-MOE-rA-3'-CE-Phosphoramidite

Description: DMTr-2'-O-MOE-rA-3'-CE-Phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified adenosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00578

CAS: 1558023-78-1

Molecular Formula: C43H54N7O8P

Molecular Weight: 827.91

Purity: ≥95% by HPLC

Appearance: White, off-white to faint yellow powder

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InChIKey: SMHLYNOCXUPBAV-NFQMNAKDSA-N

CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=NC=NC32)N)C1OCCOC)COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)N(C(C)C)C(C)C

IUPAC Name: 3-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-(2-methoxyethoxy)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C43H54N7O8P/c1-29(2)50(30(3)4)59(56-23-11-22-44)58-38-36(57-42(39(38)54-25-24-51-5)49-28-48-37-40(45)46-27-47-41(37)49)26-55-43(31-12-9-8-10-13-31,32-14-18-34(52-6)19-15-32)33-16-20-35(53-7)21-17-33/h8-10,12-21,27-30,36,38-39,42H,11,23-26H2,1-7H3,(H2,45,46,47)/t36-,38-,39-,42-,59?/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)adenosine 3'-O-(2-cyanoethyl N,N-diisopropylphosphoramidite); Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; DMT-2'-O-MOE-Ar-CE-Phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl Phosphoramidite

DMTr-2'-O-MOE-rA(Bz)-3'-CE-(1-hydroxy-N,N-diisopropyl)phosphoramidite

Description: DMTr-2'-O-MOE-rA(Bz)-3'-CE-(1-hydroxy-N,N-diisopropyl)phosphoramidite is utilized in oligonucleotide synthesis. It is employed to introduce modified adenosine residues with altered chemical properties into nucleic acid sequences, suitable for applications such as RNA interference (RNAi), gene silencing, and nucleic acid therapeutics.

CAT: BRP-00579

Molecular Formula: C47H55N6O9P

Molecular Weight: 878.96

Purity: ≥98%

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InChIKey: QDIFFXPFBYESPR-QCDZHEALSA-N

IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl hydrogen diisopropylphosphoramidite

InChI: InChI=1S/C47H55N6O9P/c1-31(2)53(32(3)4)63(55)62-41-39(28-60-47(34-16-12-9-13-17-34,35-18-22-37(57-6)23-19-35)36-20-24-38(58-7)25-21-36)61-46(42(41)59-27-26-56-5)52-30-50-40-43(48-29-49-44(40)52)51-45(54)33-14-10-8-11-15-33/h8-25,29-32,39,41-42,46,55H,26-28H2,1-7H3,(H,48,49,51,54)/t39-,41-,42-,46-,63?/m1/s1