Phosphoramidites

Biotin-dT CE-Phosphoramidite

Description: Biotin-dT CE-Phosphoramidite is a prestigious compound, engaged in the critical tasks of labeling and detecting DNA or RNA sequences. With the amalgamation of biotin, this meticulously modified nucleotide engenders a realm of convenience for meticulous purification processes, unrivaled amplification endeavors and captivating visualization techniques.

CAT: BRP-02358

CAS: 198080-40-9

Molecular Formula: C69H89N8O12PS

Molecular Weight: 1285.55

Purity: 95%

Appearance: White, off-white to light yellow powder

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Storage: Store at -20 °C

InChIKey: FHABSPMZQJOPSS-GGVSAJPNSA-N

Solubility: Soluble in Anhydrous Acetonitrile

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C=CC(=O)NCCCCCCNC(=O)CCCCC6C7C(CS6)N(C(=O)N7)C(=O)C8=CC=C(C=C8)C(C)(C)C

IUPAC Name: 5-[(3aR,6S,6aS)-3-(4-tert-butylbenzoyl)-2-oxo-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]-N-[6-[3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoylamino]hexyl]pentanamide

InChI: InChI=1S/C69H89N8O12PS/c1-46(2)77(47(3)4)90(87-41-19-38-70)89-57-42-62(88-58(57)44-86-69(51-20-13-12-14-21-51,52-29-33-54(84-8)34-30-52)53-31-35-55(85-9)36-32-53)75-43-49(64(80)74-66(75)82)26-37-61(79)72-40-18-11-10-17-39-71-60(78)23-16-15-22-59-63-56(45-91-59)76(67(83)73-63)65(81)48-24-27-50(28-25-48)68(5,6)7/h12-14,20-21,24-37,43,46-47,56-59,62-63H,10-11,15-19,22-23,39-42,44-45H2,1-9H3,(H,71,78)(H,72,79)(H,73,83)(H,74,80,82)/t56-,57-,58+,59-,62+,63-,90?/m0/s1

Synonyms: 5'-Dimethoxytrityloxy-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Biotin-dT Amidite; Biotin-dT Phosphoramidite; (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-(3-((6-(5-((3aS,4S,6aR)-1-(4-(tert-butyl)benzoyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexyl)amino)-3-oxoprop-1-en-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMTr-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-dT-3'-CE-phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxythymidine-3'-O-[(2-cyanoethyl)-N,N-diisopropyl]-phosphoramidite; Biotin-dT

3'-O-DMT-N6-Benzoyl-Cytidine TNA 2'-CE phosphoramidite

Description: TNA 2'-CE oligonucleotide synthesis necessitates 3'-O-DMT-N6-benzoyl-cytidine, and our TNA 2'-CE phosphoramidite is precisely engineered for just that purpose. Researchers within the biomedicine discipline rely heavily on our product due to their capacity to incorporate TNA monomers as they fabricate artificial nucleic acids for gene-based therapeutics and pharmacological advancement.

CAT: BRP-02365

CAS: 325683-96-3

Molecular Formula: C45H50N5O8P

Molecular Weight: 819.90

Purity: 98%

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1 g	$998	In stock
100 mg	$398	In stock

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InChIKey: URCWUOWKRJMYKD-RBZSHJCZSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(COC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)OC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

IUPAC Name: N-[1-[(2R,3R,4S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C45H50N5O8P/c1-31(2)50(32(3)4)59(56-29-13-27-46)58-41-39(30-55-43(41)49-28-26-40(48-44(49)52)47-42(51)33-14-9-7-10-15-33)57-45(34-16-11-8-12-17-34,35-18-22-37(53-5)23-19-35)36-20-24-38(54-6)25-21-36/h7-12,14-26,28,31-32,39,41,43H,13,29-30H2,1-6H3,(H,47,48,51,52)/t39-,41+,43+,59?/m0/s1

Synonyms: Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; DMTr-TNA C(Bz)-amidite; (2R,3R,4S)-2-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; TNA-C(Bz)-CE-Phosphoramidite; N-Benzoyl-1-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]cytosine; DMTr-TNA-C(Bz)-Phosphoramidite

3'-O-DMT-O6-DPC-N2-Acetyl-Guanosine TNA 2'-CE phosphoramidite

Description: 3'-O-DMT-O6-DPC-N2-Acetyl-Guanosine TNA 2'-CE phosphoramidite is a highly complex chemical compound utilized in the biomedical industry to fabricate nucleic acid-based drugs that effectively combat a multitude of ailments, including but not limited to cancer, viral infections, and genetic disorders. The intricate nature of the molecule allows for the synthesis of oligonucleotides that specifically target variably expressed genes, culminating in an unparalleled approach towards achieving precision medication. Procuring this compound necessitates a specialized skill set and equipment, and can only be obtained from esteemed chemical outlets.

CAT: BRP-02367

CAS: 325683-97-4

Molecular Formula: C54H57N8O9P

Molecular Weight: 993.05

Purity: 98%

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1 g	$998	In stock
100 mg	$398	In stock

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InChIKey: QGLNDUMJEPXLMP-DMYMLFOFSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(COC1N2C=NC3=C2N=C(N=C3OC(=O)N(C4=CC=CC=C4)C5=CC=CC=C5)NC(=O)C)OC(C6=CC=CC=C6)(C7=CC=C(C=C7)OC)C8=CC=C(C=C8)OC

IUPAC Name: [2-acetamido-9-[(2R,3R,4S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]聽N,N-diphenylcarbamate

InChI: InChI=1S/C54H57N8O9P/c1-36(2)62(37(3)4)72(68-33-17-32-55)71-48-46(70-54(39-18-11-8-12-19-39,40-24-28-44(65-6)29-25-40)41-26-30-45(66-7)31-27-41)34-67-51(48)60-35-56-47-49(60)58-52(57-38(5)63)59-50(47)69-53(64)61(42-20-13-9-14-21-42)43-22-15-10-16-23-43/h8-16,18-31,35-37,46,48,51H,17,33-34H2,1-7H3,(H,57,58,59,63)/t46-,48+,51+,72?/m0/s1

Synonyms: DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite; TNA-G(O-CONPh2)(N-Ac)CE-Phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[2-(acetylamino)-6-[[(diphenylamino)carbonyl]oxy]-9H-purin-9-yl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; 2-Acetamido-9-((2R,3R,4S)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl diphenylcarbamate

3'-O-DMT-N6-Benzoyl-Adenosine TNA 2'-CE phosphoramidite

Description: 3'-O-DMT-N6-Benzoyl-Adenosine TNA 2'-CE phosphoramidite is a modified nucleotide used in the synthesis of Threose Nucleic Acid (TNA) molecules for biomedical research. TNA is a promising alternative to DNA and RNA for gene and drug delivery due to its chemical stability and resistance to nuclease degradation. This specific phosphoramidite derivative incorporates a benzoyl-adenosine moiety, making it ideal for designing TNA-based drugs for the treatment of viral infections, inflammatory diseases, and cancer.

CAT: BRP-02380

CAS: 325683-93-0

Molecular Formula: C46H50N7O7P

Molecular Weight: 843.92

Purity: 98%

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1 g	$998	In stock
100 mg	$398	In stock

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InChIKey: QDGHMYBPKHSPSZ-BZWOVQDPSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(COC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)OC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

IUPAC Name: N-[9-[(2R,3R,4S)-4-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]benzamide

InChI: InChI=1S/C46H50N7O7P/c1-31(2)53(32(3)4)61(58-27-13-26-47)60-41-39(28-57-45(41)52-30-50-40-42(48-29-49-43(40)52)51-44(54)33-14-9-7-10-15-33)59-46(34-16-11-8-12-17-34,35-18-22-37(55-5)23-19-35)36-20-24-38(56-6)25-21-36/h7-12,14-25,29-32,39,41,45H,13,27-28H2,1-6H3,(H,48,49,51,54)/t39-,41+,45+,61?/m0/s1

Synonyms: DMTr-TNA A(Bz)-amidite; TNA-A(Bz)-CE-Phosphoramidite; DMTr-TNA A(Bz)-Phosphoramidite; N-Benzoyl-9-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]-9H-purine-6-amine; 1-{2'-O-[(2-Cyanoethoxy)(diisopropyl amino)phosphino]-3'-O-[(4,4'-dimethoxytriphenyl)methyl]-a-L-threofuranosyl}-N6-benzoyladenine; (2R,3R,4S)-2-[6-(Benzoylamino)-9H-purin-9-yl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[6-(benzoylamino)-9H-purin-9-yl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2R,3R,4S)-2-[6-(benzoylamino)-9H-purin-9-yl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester

DMTr-LNA-C(Bz)-3-CED-phosphoramidite

Description: DMTr-LNA-C(Bz)-3-CED-phosphoramidite is a purine nucleoside analog which has broad antitumor activity targeting indolent lymphoid malignancies.

CAT: BRP-00015

CAS: 206055-78-9

Molecular Formula: C47H52N5O9P

Molecular Weight: 861.93

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InChIKey: SSGINSHBUWKRHC-XCHZTBEFSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C2C(OC1(CO2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)N6C=CC(=NC6=O)NC(=O)C7=CC=CC=C7

IUPAC Name: N-[1-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C47H52N5O9P/c1-32(2)52(33(3)4)62(59-29-13-27-48)61-42-41-44(51-28-26-40(50-45(51)54)49-43(53)34-14-9-7-10-15-34)60-46(42,30-57-41)31-58-47(35-16-11-8-12-17-35,36-18-22-38(55-5)23-19-36)37-20-24-39(56-6)25-21-37/h7-12,14-26,28,32-33,41-42,44H,13,29-31H2,1-6H3,(H,49,50,53,54)/t41-,42+,44-,46-,62?/m1/s1

Synonyms: LNA-C(Bz)-CE Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-LNA-cytidine-3'-cyanoethyl phosphoramidite; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O,4'-C-methylene-cytidine 3'-O-[(2-cyanoethyl) (N,N-diisopropyl)]-phosphorramidite; 5'-O-DMTr-2'-O-4'-C-Locked-C(Bz) Phosphoramidite; DMT-locC(bz)Amidite; DMT-locC(bz) phosphoramidite; LNA-C(Bz)-3-CED-phosphoramidite; Bz-C-LA-CE Phosphoramidite

DMTr-LNA-G(iBu)-3'-CED-phosphoramidite

Description: DMTr-LNA-G(iBu)-3'-CED-phosphoramidite is a phosphoramidite used in the biomedical industry for the synthesis of modified nucleic acids. It contains DMTr-protected LNA-G(iBu)-3'-CED, which enables efficient and stable incorporation of modified bases during DNA/RNA synthesis.

CAT: BRP-00016

CAS: 206055-77-8

Molecular Formula: C45H54N7O9P

Molecular Weight: 867.94

Purity: ≥98% by HPLC

Appearance: Off-white to yellow powder

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InChIKey: UUBFSNDSLDOIDQ-NIQOLRRHSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C4C(C(O3)(CO4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)OP(N(C(C)C)C(C)C)OCCC#N

IUPAC Name: N-[9-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C45H54N7O9P/c1-28(2)40(53)49-43-48-39-36(41(54)50-43)47-27-51(39)42-37-38(61-62(59-24-12-23-46)52(29(3)4)30(5)6)44(60-42,25-57-37)26-58-45(31-13-10-9-11-14-31,32-15-19-34(55-7)20-16-32)33-17-21-35(56-8)22-18-33/h9-11,13-22,27-30,37-38,42H,12,24-26H2,1-8H3,(H2,48,49,50,53,54)/t37-,38+,42-,44-,62?/m1/s1

Synonyms: N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-LNA-guanosine-3'-cyanoethyl phosphoramidite; LNA-G(ibu) phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O,4'-C-methyleneguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; LNA-G(iBu)-CE Phosphoramidite; DMTr-2'-O-4'-C-Locked-rG(iBu)-3'-CE-Phosphoramidite; DMT-2'-O-4'-C-Locked-G(iBu)-CE; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-Guanosine-3'-cyanoethyl Phosphoramidite; N2-iBu-2'-O-4'-C-Locked-Gr-CE-Phosphoramidite

iBu-G-(S)-GNA phosphoramidite

Description: Bz-G-(S)-GNA phosphoramidite: A Potent Anticancer and Antiviral Reagent for DNA Synthesis and Modification. This widely employed derivative is recognized for its high-purity and stability, enabling the synthesis of oligonucleotides with amplified efficacy and selectivity. Renowned for its use in drug discovery and development, the Bz-G-(S)-GNA nucleoside intermediate supports treatment of devastating conditions like HIV and cancer.

CAT: BRP-00085

CAS: 182625-68-9

Molecular Formula: C44H52N7O7P

Molecular Weight: 797.88

Purity: ≥98%

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InChIKey: GOUPKQZMFOWLOW-AUNMUFMCSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2CC(COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N(C(C)C)C(C)C)OCCC#N

IUPAC Name: N-[9-[(2S)-3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropyl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C42H52N7O7P/c1-28(2)39(50)46-41-45-38-37(40(51)47-41)44-27-48(38)25-36(56-57(55-24-12-23-43)49(29(3)4)30(5)6)26-54-42(31-13-10-9-11-14-31,32-15-19-34(52-7)20-16-32)33-17-21-35(53-8)22-18-33/h9-11,13-22,27-30,36H,12,24-26H2,1-8H3,(H2,45,46,47,50,51)/t36-,57?/m0/s1

Synonyms: 2'-O-(2-Cyanoethoxy)(diisopropylamino)phosphino-3'-O-(4,4'-dimethoxytriphenyl)methyl-N2-isobutyryl-(S)-9-(2,3-dihydroxypropyl)guanine; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S)-2-[bis(4-methoxyphenyl)phenylmethoxy]-1-[[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]methyl]ethyl 2-cyanoethyl ester; (S)-1-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite; (S)-GNA-G(iBu) phosphoramidite; DMT-G(iBu)-(S)-GNA Phosphoramidite

N6-Bz-A-(S)-GNA phosphoramidite

Description: N6-Bz-A-(S)-GNA phosphoramidite, a chemical utilized in the synthesis of oligonucleotides for molecular biology study, imitates nucleotide bases to scrutinize RNA/DNA structure and function. Furthermore, it assists in the creation of disease-specific gene-targeting medications.

CAT: BRP-00118

CAS: 851050-24-3

Molecular Formula: C45H50N7O6P

Molecular Weight: 815.90

Purity: ≥98%

Appearance: White, off-white to faint yellow powder

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InChIKey: RHPZFMWWZNRHHT-MXHUVDEASA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC(CN1C=NC2=C(N=CN=C21)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

IUPAC Name: N-[9-[(2S)-3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropyl]purin-6-yl]benzamide

InChI: InChI=1S/C45H50N7O6P/c1-32(2)52(33(3)4)59(57-27-13-26-46)58-40(28-51-31-49-41-42(47-30-48-43(41)51)50-44(53)34-14-9-7-10-15-34)29-56-45(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-25,30-33,40H,13,27-29H2,1-6H3,(H,47,48,50,53)/t40-,59?/m0/s1

Synonyms: (S)-GNA-A(Bz)-phosphoramidite; N6-benzoyl-(S)-1-(4,4'-dimethoxytrityl)-3-adenosine-2-cyanoethyl Phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (1S)-1-[[6-(benzoylamino)-9H-purin-9-yl]methyl]-2-[bis(4-methoxyphenyl)phenylmethoxy]ethyl 2-cyanoethyl ester; (1S)-1-[[6-(Benzoylamino)-9H-purin-9-yl]methyl]-2-[bis(4-methoxyphenyl)phenylmethoxy]ethyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; (S)-G-A(Bz)-phosphoramidite; (S)-1-(6-Benzamido-9H-purin-9-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite

5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite

Description: 5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite is a phosphoramidite derivative used in the synthesis of modified oligonucleotides for biomedical research. It enables the incorporation of 2'-O-methyl-pseudouridine modifications into RNA sequences, enhancing stability and specific RNA-protein interactions.

CAT: BRP-00128

CAS: 199737-09-2

Molecular Formula: C40H49N4O9P

Molecular Weight: 760.81

Purity: ≥95% by HPLC

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InChIKey: QRORKJSFBIFPIM-ALEZOLFBSA-N

CanonicalSMILES: N#CCCOP(OC1C(OC(C2=CNC(=O)NC2=O)C1OC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)N(C(C)C)C(C)C

IUPAC Name: (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C40H49N4O9P/c1-26(2)44(27(3)4)54(51-23-11-22-41)53-36-34(52-35(37(36)49-7)33-24-42-39(46)43-38(33)45)25-50-40(28-12-9-8-10-13-28,29-14-18-31(47-5)19-15-29)30-16-20-32(48-6)21-17-30/h8-10,12-21,24,26-27,34-37H,11,23,25H2,1-7H3,(H2,42,43,45,46)/t34-,35+,36-,37+,54?/m1/s1

Synonyms: 2'-O-Methyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; pseudoUridine (with 5'-DMT, 3'-phosphoramidite, and 2'-OMe); 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione

5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite

Description: It is a modified ribonucleoside analogue suitable for incorporation into small interfering RNA (siRNA) to enhance RNA stability in biological applications such as gene silencing.

CAT: BRP-00130

CAS: 875302-45-7

Molecular Formula: C46H63N4O9PSi

Molecular Weight: 875.07

Purity: ≥98%

Appearance: White to off-white powder

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InChIKey: ZDZLHJPETUXZJT-NSASEYFNSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)C2=CN(C(=O)NC2=O)C)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1S/C46H63N4O9PSi/c1-31(2)50(32(3)4)60(56-28-16-27-47)58-41-39(57-40(38-29-49(8)44(52)48-43(38)51)42(41)59-61(11,12)45(5,6)7)30-55-46(33-17-14-13-15-18-33,34-19-23-36(53-9)24-20-34)35-21-25-37(54-10)26-22-35/h13-15,17-26,29,31-32,39-42H,16,28,30H2,1-12H3,(H,48,51,52)/t39-,40+,41-,42+,60?/m1/s1

Synonyms: 5'-Dimethoxytrityl-1-methyl-pseudouridine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-1-methyl-2,4(1H,3H)-pyrimidinedione; 2'-O-TBDMS-N1-Me-Pseudouridine CEP; 5'-O-DMTr-2'-O-TBDMS-N1-methylpseudouridine 3'-(cyanoethyl-N,N-diisopropyl)phosphoramidite; 5'-O-DMT-2'-O-TBDMS-N1-Me-pU Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-N1-methyl-Pseudouridine-3'-cyanoethyl Phosphoramidite

N4-Ac-C-(S)-GNA phosphoramidite

Description: N4-Ac-C-(S)-GNA phosphoramidite- a paramount ingredient utilized in the synthesis of nucleic acids and their analogs- holds significant potential as a therapeutic agent for a plethora of viral diseases including but not limited to coronavirus, influenza, and HIV. Additionally, it finds relevance in the research concerning genetic engineering and gene therapy - substantially empowering cutting-edge biosciences.

CAT: BRP-00131

CAS: 1159174-80-7

Molecular Formula: C39H48N5O7P

Molecular Weight: 729.8

Purity: ≥98%

Appearance: White to off-white powder

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InChIKey: GJBIWQXFRRQYML-RRUDDRBXSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC(CN1C=CC(=NC1=O)NC(=O)C)COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC

IUPAC Name: N-[1-[(2S)-3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropyl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C39H48N5O7P/c1-28(2)44(29(3)4)52(50-25-11-23-40)51-36(26-43-24-22-37(41-30(5)45)42-38(43)46)27-49-39(31-12-9-8-10-13-31,32-14-18-34(47-6)19-15-32)33-16-20-35(48-7)21-17-33/h8-10,12-22,24,28-29,36H,11,25-27H2,1-7H3,(H,41,42,45,46)/t36-,52?/m0/s1

Synonyms: N4-acetyl-(S)-1-(4,4'-dimethoxytrityl)-3-cytidine-2-cyanoethyl Phosphoramidite; (S)-1-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite; (1S)-2-[4-(Acetylamino)-2-oxo-1(2H)-pyrimidinyl]-1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]ethyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; GNA-S-C(Ac)-Phosphoramidite

UNA-A(Bz)-CE Phosphoramidite

Description: UNA-A(Bz)-CE Phosphoramidite is an advanced biomedical compound used for the research of cancer, including breast and lung cancer. It acts by targeting specific cellular pathways involved in cancer progression, inhibiting tumor growth and promoting cell death.

CAT: BRP-00132

CAS: 1120329-52-3

Molecular Formula: C54H58N7O9P

Molecular Weight: 980.06

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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InChIKey: DETQAICZNNZAEM-OWWCMFKUSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCC(COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)OC(COC(=O)C4=CC=CC=C4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7

IUPAC Name: [(2R)-2-(6-benzamidopurin-9-yl)-2-[(2R)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]oxyethyl] benzoate

InChI: InChI=1S/C54H58N7O9P/c1-38(2)61(39(3)4)71(68-32-16-31-55)69-34-47(33-67-54(42-21-14-9-15-22-42,43-23-27-45(64-5)28-24-43)44-25-29-46(65-6)30-26-44)70-48(35-66-53(63)41-19-12-8-13-20-41)60-37-58-49-50(56-36-57-51(49)60)59-52(62)40-17-10-7-11-18-40/h7-15,17-30,36-39,47-48H,16,32-35H2,1-6H3,(H,56,57,59,62)/t47-,48-,71?/m1/s1

Synonyms: N6-Benzoyl-(5'-(4,4'-dimethoxytrityl)-2'-benzoyl-2',3'-seco-adenosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)] phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2R)-2-[(1R)-1-[6-(benzoylamino)-9H-purin-9-yl]-2-(benzoyloxy)ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester; (2R)-2-[(1R)-1-[6-(Benzoylamino)-9H-purin-9-yl]-2-(benzoyloxy)ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite

UNA-G(iBu)-CE Phosphoramidite

Description: UNA-G(iBu)-CE Phosphoramidite is a uniquely intricate compound possessing potential applications in the realm of cancer therapeutics. Possessing potent antineoplastic capabilities, it demonstrates high efficacy in the research of obstruction in malignant cellular proliferation.

CAT: BRP-00133

CAS: 1120329-61-4

Molecular Formula: C51H60N7O10P

Molecular Weight: 962.04

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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InChIKey: PCZJDFIZVYBABW-WESQYFQMSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C(COC(=O)C3=CC=CC=C3)OC(COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)COP(N(C(C)C)C(C)C)OCCC#N

IUPAC Name: [(2R)-2-[(2R)-1-[bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]oxy-2-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]ethyl] benzoate

InChI: InChI=1S/C51H60N7O10P/c1-34(2)47(59)55-50-54-46-45(48(60)56-50)53-33-57(46)44(32-64-49(61)37-16-11-9-12-17-37)68-43(31-67-69(66-29-15-28-52)58(35(3)4)36(5)6)30-65-51(38-18-13-10-14-19-38,39-20-24-41(62-7)25-21-39)40-22-26-42(63-8)27-23-40/h9-14,16-27,33-36,43-44H,15,29-32H2,1-8H3,(H2,54,55,56,59,60)/t43-,44-,69?/m1/s1

Synonyms: N2-Isobutyryl-(5'-(4,4'-dimethoxytrityl)-2'-benzoyl-2',3'-seco-guanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)] phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (2R)-2-[(1R)-2-(benzoyloxy)-1-[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl ester; (2R)-2-[(1R)-2-(Benzoyloxy)-1-[1,6-dihydro-2-[(2-methyl-1-oxopropyl)amino]-6-oxo-9H-purin-9-yl]ethoxy]-3-[bis(4-methoxyphenyl)phenylmethoxy]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite

Yakima Yellow® Phosphoramidite

Description: Yakima Yellow Phosphoramidite is a fluorescent dye with a maximum absorbance of 530 nm and an emission maximum of 549 nm. It has similar excitation and emission characteristics to VIC, JOE, HEX, and Alexa Fluor 532.

CAT: BRP-00218

CAS: 502485-39-4

Molecular Formula: C49H60Cl4N3O10P

Molecular Weight: 1023.81

Appearance: Off-white solid

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InChIKey: POEPDWFKAYRZJK-UHFFFAOYSA-N

CanonicalSMILES: CC1=C2C(=CC(=C1OC(=O)C(C)(C)C)Cl)C3(C4=CC(=C(C=C4C(=O)O3)Cl)Cl)C5=C(O2)C(=C(C(=C5)CCC(=O)NCCCCCCOP(N(C(C)C)C(C)C)OCCC#N)OC(=O)C(C)(C)C)Cl

IUPAC Name: [2',5,5',6-tetrachloro-7'-[3-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylamino]-3-oxopropyl]-6'-(2,2-dimethylpropanoyloxy)-4'-methyl-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate

InChI: InChI=1S/C49H60Cl4N3O10P/c1-27(2)56(28(3)4)67(62-22-16-19-54)61-21-15-13-12-14-20-55-38(57)18-17-30-23-33-43(39(53)42(30)65-46(60)48(9,10)11)63-40-29(5)41(64-45(59)47(6,7)8)37(52)26-34(40)49(33)32-25-36(51)35(50)24-31(32)44(58)66-49/h23-28H,12-18,20-22H2,1-11H3,(H,55,57)

Synonyms: Y-Yellow Phosphoramidite; Yakima Yellow; 3-(5,6,4',7'-tetrachloro-5'-methyl-3',6'-dipivaloylfluorescein-2-yl)-propanamidohexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 1,1'-[2'-[12-[Bis(1-methylethyl)amino]-15-cyano-3-oxo-11,13-dioxa-4-aza-12-phosphapentadec-1-yl]-4',5,6,7'-tetrachloro-5'-methyl-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] bis(2,2-dimethylpropanoate); Propanoic acid, 2,2-dimethyl-, 2'-[3-[[6-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]hexyl]amino]-3-oxopropyl]-4',5,6,7'-tetrachloro-5'-methyl-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; Epoch Yakima Yellow Phosphoramidite; Yakima Yellow Amidite; Yakima Yellow Phosphoramidite

DyLight 3 CEP

Description: DyLight 3 CEP is a fluorescent dye used for oligonucleotide labeling.

CAT: BRP-00220

CAS: 182873-76-3

Molecular Formula: C58H70CIN4O4P

Molecular Weight: 953.64

Purity: ≥90%

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InChIKey: DQXAVRZQYYKELZ-UHFFFAOYSA-M

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC[N+]1=C(C(C2=CC=CC=C21)(C)C)C=CC=C3C(C4=CC=CC=C4N3CCCOC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=C(C=C7)OC)(C)C)OCCC#N.[Cl-]

IUPAC Name: 3-[[di(propan-2-yl)amino]-[3-[2-[3-[1-[3-[(4-methoxyphenyl)-diphenylmethoxy]propyl]-3,3-dimethylindol-2-ylidene]prop-1-enyl]-3,3-dimethylindol-1-ium-1-yl]propoxy]phosphanyl]oxypropanenitrile;chloride

InChI: InChI=1S/C58H70N4O4P.ClH/c1-44(2)62(45(3)4)67(65-42-21-38-59)66-43-23-40-61-53-31-19-17-29-51(53)57(7,8)55(61)33-20-32-54-56(5,6)50-28-16-18-30-52(50)60(54)39-22-41-64-58(46-24-12-10-13-25-46,47-26-14-11-15-27-47)48-34-36-49(63-9)37-35-48;/h10-20,24-37,44-45H,21-23,39-43H2,1-9H3;1H/q+1;/p-1

Synonyms: Cy3 MMTr CE Phosphoramidite; 1-[3-(4-monomethoxytrityloxy)propyl]-1'-[3-[(2-cyanoethyl)-(N,N-diisopropyl)phosphoramidityl]propyl]-3,3,3',3'-tetramethylindocarbocyanine chloride; Cyanine 3 Phosphoramidite

Related CAS: 718594-66-2 (free base)

Eclipse® Quencher Phosphoramidite

Description: Eclipse® Quencher Phosphoramidite is a paramount constituent employed in the fabrication of oligonucleotides, emerges as a pivotal ensemble. Its functions lie in its ability to dampen the fluorescence signal within nucleotide probes, consequently facilitating meticulous identification of distinctive DNA or RNA sequences. It substantiates its worth by contributing to the proficiency of diagnostic assays and molecular biology research, consequently augmenting the detection and scrutiny of assorted maladies and genetic irregularities.

CAT: BRP-00227

CAS: 916753-64-5

Molecular Formula: C52H61CIN7O8P

Molecular Weight: 978.51

Appearance: Black solid

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Boiling Point: 962.2±65.0 °C (Predicted)

InChIKey: CXNVOZCFZYENEQ-SOWLJRCBNA-N

CanonicalSMILES: N#CCCOP(OC1CN(C(=O)CCCN(C2=CC=C(N=NC3=CC=C(C=C3Cl)N(=O)=O)C=C2)C)C(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C1)N(C(C)C)C(C)C

IUPAC Name: rel-(3R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-1-(4-((4-((2-chloro-4-nitrophenyl)diazenyl)phenyl)(methyl)amino)butanoyl)pyrrolidin-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChI: InChI=1/C52H61ClN7O8P/c1-37(2)59(38(3)4)69(67-32-12-30-54)68-48-33-45(36-66-52(39-13-9-8-10-14-39,40-16-25-46(64-6)26-17-40)41-18-27-47(65-7)28-19-41)58(35-48)51(61)15-11-31-57(5)43-22-20-42(21-23-43)55-56-50-29-24-44(60(62)63)34-49(50)53/h8-10,13-14,16-29,34,37-38,45,48H,11-12,15,31-33,35-36H2,1-7H3/t45-,48+,69?/s2

Synonyms: EclipseQ Phosphoramidite; Eclipse Quencher Phosphoramidite; 4-N-methyl-N-(4'-nitro-2'-chloroazobenzen-4-yl)-aminobutanamido-1-(2-O-dimethoxytrityloxymethyl)-pyrrolidin-4-yl-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramdite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, (3R,5S)-5-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[4-[[4-[2-(2-chloro-4-nitrophenyl)diazenyl]phenyl]methylamino]-1-oxobutyl]-3-pyrrolidinyl 2-cyanoethyl ester, rel-; rel-(3R,5S)-5-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-1-[4-[[4-[2-(2-chloro-4-nitrophenyl)diazenyl]phenyl]methylamino]-1-oxobutyl]-3-pyrrolidinyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; 5'-Eclipse Amidite

5'-Amino Modifier C3-TFA CE Phosphoramidite

Description: 5'-Amino Modifier C3-TFA CE Phosphoramidite is a valuable product used in the biomedical industry for the synthesis of modified nucleic acids. This phosphoramidite reagent allows for the introduction of an amino modifier group at the 5' position of nucleosides, enabling the creation of modified oligonucleotides with enhanced properties. It finds applications in various fields such as drug discovery, gene synthesis, and molecular diagnostics.

CAT: BRP-00229

CAS: 853955-89-2

Molecular Formula: C14H25F3N3O3P

Molecular Weight: 371.34

Appearance: Colorless Oil

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Boiling Point: 391.4±42.0 °C at 760 mmHg

InChIKey: AOAXRHUQUZSDAX-UHFFFAOYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCCNC(=O)C(F)(F)F)OCCC#N

IUPAC Name: N-[3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropyl]-2,2,2-trifluoroacetamide

InChI: InChI=1S/C14H25F3N3O3P/c1-11(2)20(12(3)4)24(22-9-5-7-18)23-10-6-8-19-13(21)14(15,16)17/h11-12H,5-6,8-10H2,1-4H3,(H,19,21)

Synonyms: 5'-Amino Modifier C3 TFA CE Phosphoramidite; 5'-Amino-modifier-C 3-tfa cep; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 3-[(trifluoroacetyl)amino]propyl ester; 2-Cyanoethyl 3-[(trifluoroacetyl)amino]propyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 3-[(trifluoroacetyl)amino]propyl ester; 5'-Amino-Modifier C3-TFA

5'-BHQ-1 Phosphoramidite

Description: 5'-BHQ-1 Phosphoramidite, an indispensable reagent, is widely employed in synthesizing oligonucleotides with numerous biomedical potentialities. A notable function is creating luminous probes for detecting nucleic acid sequences in vivo and in vitro. Moreover, it has crucially contributed to the progress in crafting diagnostic devices for malignant neoplasms, viral infections and innate deficiencies.

CAT: BRP-00234

CAS: 1430816-77-5

Molecular Formula: C34H45N8O5P

Molecular Weight: 676.75

Purity: ≥98% by HPLC

Appearance: Dark red solid

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InChIKey: PYSPQPFQYWCYDV-UHFFFAOYSA-N

CanonicalSMILES: CCN(CCOP(N(C(C)C)C(C)C)OCCC#N)C1=CC=C(C=C1)N=NC2=C(C=C(C(=C2)C)N=NC3=C(C=C(C=C3)C)[N+](=O)[O-])OC

IUPAC Name: 3-[[di(propan-2-yl)amino]-[2-[N-ethyl-4-[[2-methoxy-5-methyl-4-[(4-methyl-2-nitrophenyl)diazenyl]phenyl]diazenyl]anilino]ethoxy]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C34H45N8O5P/c1-9-40(18-20-47-48(46-19-10-17-35)41(24(2)3)25(4)5)29-14-12-28(13-15-29)36-39-32-22-27(7)31(23-34(32)45-8)38-37-30-16-11-26(6)21-33(30)42(43)44/h11-16,21-25H,9-10,18-20H2,1-8H3

Synonyms: 4'-(2-Nitro-4-toluyldiazo)-2'-methoxy-5'-methyl-azobenzene-4''-(N-ethyl)-N-ethyl-2-cyanoethyl-(N,N-diisopropyl)-phosphoramidite; 5'-HDQ-1 Phosphoramidite; BHQ-1-Amidite; BHQ-1 Amidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 2-[ethyl[4-[2-[2-methoxy-5-methyl-4-[2-(4-methyl-2-nitrophenyl)diazenyl]phenyl]diazenyl]phenyl]amino]ethyl ester; 2-Cyanoethyl 2-[ethyl[4-[2-[2-methoxy-5-methyl-4-[2-(4-methyl-2-nitrophenyl)diazenyl]phenyl]diazenyl]phenyl]amino]ethyl N,N-bis(1-methylethyl)phosphoramidite; DusQ1 amidite, 5'-terminal

5'-BHQ-2 Phosphoramidite

Description: 5'-BHQ-2 Phosphoramidite is integral in the synthesis of oligonucleotides for cutting-edge biomedical investigations and diagnostics, showcasing its prowess as a fluorescent quencher. It expedites the identification and evaluation of diverse DNA and RNA patterns. With unparalleled efficacy and unwavering consistency, it fulfills an optimal role in real-time PCR, next-generation sequencing is and hybridization assays.

CAT: BRP-00235

CAS: 1345959-73-0

Molecular Formula: C33H43N8O6P

Molecular Weight: 678.72

Purity: ≥98% by HPLC

Appearance: Dark purple solid

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InChIKey: OXESOGDAJXFPNE-UHFFFAOYSA-N

CanonicalSMILES: CCN(CCOP(N(C(C)C)C(C)C)OCCC#N)C1=CC=C(C=C1)N=NC2=CC(=C(C=C2OC)N=NC3=CC=C(C=C3)[N+](=O)[O-])OC

IUPAC Name: 3-[2-[4-[[2,5-dimethoxy-4-[(4-nitrophenyl)diazenyl]phenyl]diazenyl]-N-ethylanilino]ethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C33H43N8O6P/c1-8-39(19-21-47-48(46-20-9-18-34)40(24(2)3)25(4)5)28-14-10-26(11-15-28)35-37-30-22-33(45-7)31(23-32(30)44-6)38-36-27-12-16-29(17-13-27)41(42)43/h10-17,22-25H,8-9,19-21H2,1-7H3

Synonyms: 4'-(4-Nitro-phenyldiazo)-2'-methoxy-5'-methoxy-azobenzene-4''-(N-ethyl)-N-ethyl-2-cyanoethyl-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 2-[[4-[2-[2,5-dimethoxy-4-[2-(4-nitrophenyl)diazenyl]phenyl]diazenyl]phenyl]ethylamino]ethyl ester; 2-Cyanoethyl 2-[[4-[2-[2,5-dimethoxy-4-[2-(4-nitrophenyl)diazenyl]phenyl]diazenyl]phenyl]ethylamino]ethyl N,N-bis(1-methylethyl)phosphoramidite; BHQ-2-Amidite; BHQ-2 Amidite

5'-Aldehyde-Modifier C2 Phosphoramidite

Description: 5'-Aldehyde-Modifier C2 Phosphoramidite, an essential reagent for bioconjugation and labeling of oligonucleotides, is an attractive option for introducing aldehydes into DNA strands in a site-selective and efficient manner. With its potential applications in gene editing, diagnostics, and drug discovery, this product provides researchers with a versatile tool for developing advanced therapies. The wide range of possibilities provided by this reagent sets it apart from other options on the market, making it an essential component in any research lab dealing with DNA analyses.

CAT: BRP-00236

CAS: 433684-36-7

Molecular Formula: C25H41N2O5P

Molecular Weight: 480.58

Purity: ≥95%

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Storage: Store at -20 °C

InChIKey: JCAVMJJPXGZACF-UHFFFAOYSA-N

Solubility: Soluble in Anhydrous Acetonitrile

CanonicalSMILES: N#CCCOP(OCCOC1=CC=C(C=C1)C2OCC(CO2)(CC)CC)N(C(C)C)C(C)C

InChI: InChI=1S/C25H41N2O5P/c1-7-25(8-2)18-29-24(30-19-25)22-10-12-23(13-11-22)28-16-17-32-33(31-15-9-14-26)27(20(3)4)21(5)6/h10-13,20-21,24H,7-9,15-19H2,1-6H3

Synonyms: 5'-Aldehyde-C2 Amidite; 2-[4-(5,5-Diethyl-1,3-dioxan-2-yl)phenoxy]ethan-1-yl-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 2-[4-(5,5-diethyl-1,3-dioxan-2-yl)phenoxy]ethyl ester; 2-Cyanoethyl 2-[4-(5,5-diethyl-1,3-dioxan-2-yl)phenoxy]ethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 2-[4-(5,5-diethyl-1,3-dioxan-2-yl)phenoxy]ethyl ester

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