Phosphoramidites - RNA / BOC Sciences

Fmoc-PNA-C(Bhoc)-OH

Description: Fmoc-PNA-C(Bhoc)-OH is a cytosine-containing peptide nucleic acid (PNA) monomer that is protected with an Fmoc (fluorenylmethyloxycarbonyl) group at the N-terminus and a Bhoc (benzhydryloxycarbonyl) group protecting the cytosine base. Fmoc-PNA-C(Bhoc)-OH is a protected PNA monomer used in the synthesis of peptide nucleic acids, offering specificity for guanine binding, stability against enzymatic degradation, and strong hybridization properties. It is widely used in genetic diagnostics, antisense therapy, and various molecular biology applications.

CAT: BRP-02043

CAS: 186046-81-1

MF: C39H35N5O8

MF: 701.73

Purity: ≥95%

Appearance: White to off-white powder

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Storage: Store at 2-8 °C

Density: 1.34±0.1 g/cm3

InChIKey: YPTOIRLDQISSCH-UHFFFAOYSA-N

CanonicalSMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)OC(=O)NC3=NC(=O)N(C=C3)CC(=O)N(CCNC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46)CC(=O)O

IUPAC Name: 2-[[2-[4-(benzhydryloxycarbonylamino)-2-oxopyrimidin-1-yl]acetyl]-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]amino]acetic acid

InChI: InChI=1S/C39H35N5O8/c45-34(23-44-21-19-33(41-37(44)48)42-39(50)52-36(26-11-3-1-4-12-26)27-13-5-2-6-14-27)43(24-35(46)47)22-20-40-38(49)51-25-32-30-17-9-7-15-28(30)29-16-8-10-18-31(29)32/h1-19,21,32,36H,20,22-25H2,(H,40,49)(H,46,47)(H,41,42,48,50)

Synonyms: 2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(4-(((benzhydryloxy)carbonyl)amino)-2-oxopyrimidin-1(2H)-yl)acetamido)acetic acid; Glycine, N-[[4-[[(diphenylmethoxy)carbonyl]amino]-2-oxo-1(2H)-pyrimidinyl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]-; N-[2-[4-[[(Diphenylmethoxy)carbonyl]amino]-2-oxo-1(2H)-pyrimidinyl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; Fmoc PNA-C(Bhoc)-OH; Fmoc-C(Bhoc)-Aeg-OH; PNA C Monomer

Fmoc-PNA-A(Bhoc)-OH

Description: Fmoc-PNA-A(Bhoc)-OH is an adenine-containing peptide nucleic acid (PNA) monomer that is protected with an Fmoc (fluorenylmethyloxycarbonyl) group at the N-terminus and a Bhoc (benzhydryloxycarbonyl) group protecting the adenine base. Fmoc-PNA-A(Bhoc)-OH is a protected PNA monomer used in the synthesis of peptide nucleic acids, offering specificity for thymine (or uracil) binding, stability against enzymatic degradation, and strong hybridization properties. It is widely used in genetic diagnostics, antisense therapy, and various molecular biology applications.

CAT: BRP-02044

CAS: 186046-82-2

MF: C40H35N7O7

MF: 725.75

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at 2-8 °C

Density: 1.39±0.1 g/cm3

InChIKey: LVVQRXRVCLWIIO-UHFFFAOYSA-N

CanonicalSMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)OC(=O)NC3=C4C(=NC=N3)N(C=N4)CC(=O)N(CCNC(=O)OCC5C6=CC=CC=C6C7=CC=CC=C57)CC(=O)O

IUPAC Name: 2-[[2-[6-(benzhydryloxycarbonylamino)purin-9-yl]acetyl]-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]amino]acetic acid

InChI: InChI=1S/C40H35N7O7/c48-33(46(22-34(49)50)20-19-41-39(51)53-23-32-30-17-9-7-15-28(30)29-16-8-10-18-31(29)32)21-47-25-44-35-37(42-24-43-38(35)47)45-40(52)54-36(26-11-3-1-4-12-26)27-13-5-2-6-14-27/h1-18,24-25,32,36H,19-23H2,(H,41,51)(H,49,50)(H,42,43,45,52)

Synonyms: 2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(6-(((benzhydryloxy)carbonyl)amino)-9H-purin-9-yl)acetamido)acetic acid; Fmoc-A(Bhoc)-Aeg-OH; Fmoc PNA-A(Bhoc)-OH; Glycine, N-[[6-[[(diphenylmethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]-; PNA A Monomer; N-[2-[6-[[(Diphenylmethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; Fmoc-A-(Bhoc)-OH; Fmoc-PNA-adenine(Bhoc)-OH

Fmoc-PNA-G(Bhoc)-OH

Description: Fmoc-PNA-G(Bhoc)-OH is a guanine-containing peptide nucleic acid (PNA) monomer that is protected with an Fmoc (fluorenylmethyloxycarbonyl) group at the N-terminus and a Bhoc (benzhydryloxycarbonyl) group protecting the guanine base. Fmoc-PNA-G(Bhoc)-OH is a protected PNA monomer used in the synthesis of peptide nucleic acids, offering specificity for cytosine binding, stability against enzymatic degradation, and strong hybridization properties. It is widely used in genetic diagnostics, antisense therapy, and various molecular biology applications.

CAT: BRP-02045

CAS: 186046-83-3

MF: C40H35N7O8

MF: 741.75

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at 2-8 °C

Density: 1.43±0.1 g/cm3

InChIKey: ZNHVLNAONKUINW-UHFFFAOYSA-N

CanonicalSMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)OC(=O)NC3=NC4=C(C(=O)N3)N=CN4CC(=O)N(CCNC(=O)OCC5C6=CC=CC=C6C7=CC=CC=C57)CC(=O)O

IUPAC Name: 2-[[2-[2-(benzhydryloxycarbonylamino)-6-oxo-1H-purin-9-yl]acetyl]-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]amino]acetic acid

InChI: InChI=1S/C40H35N7O8/c48-32(46(22-33(49)50)20-19-41-39(52)54-23-31-29-17-9-7-15-27(29)28-16-8-10-18-30(28)31)21-47-24-42-34-36(47)43-38(44-37(34)51)45-40(53)55-35(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-18,24,31,35H,19-23H2,(H,41,52)(H,49,50)(H2,43,44,45,51,53)

Synonyms: Glycine, N-[[2-[[(diphenylmethoxy)carbonyl]amino]-1,6-dihydro-6-oxo-9H-purin-9-yl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]-; N-[2-[2-[[(Diphenylmethoxy)carbonyl]amino]-1,6-dihydro-6-oxo-9H-purin-9-yl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; 2-[N-[2-(Fmoc-amino)ethyl]-2-[2-[[(benzhydryloxy)carbonyl]amino]-6-oxo-1H-purin-9(6H)-yl]acetamido]acetic Acid; Fmoc-G(Bhoc)-Aeg-OH; Fmoc PNA-G-(Bhoc)-OH; PNA G Monomer

Fmoc-PNA-T-OH

Description: Fmoc-PNA-T-OH is a protected peptide nucleic acid (PNA) monomer used in the synthesis of peptide nucleic acids, offering specificity for adenine binding, stability against enzymatic degradation, and strong hybridization properties. It is widely used in genetic diagnostics, antisense therapy, and various molecular biology applications.

CAT: BRP-02046

CAS: 169396-92-3

MF: C26H26N4O7

MF: 506.51

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Storage: Store at 2-8 °C

Density: 1.368±0.06 g/cm3

InChIKey: REUYSHQBEXUIRY-UHFFFAOYSA-N

CanonicalSMILES: CC1=CN(C(=O)NC1=O)CC(=O)N(CCNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)CC(=O)O

IUPAC Name: 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl-[2-(5-methyl-2,4-dioxopyrimidin-1-yl)acetyl]amino]acetic acid

InChI: InChI=1S/C26H26N4O7/c1-16-12-30(25(35)28-24(16)34)13-22(31)29(14-23(32)33)11-10-27-26(36)37-15-21-19-8-4-2-6-17(19)18-7-3-5-9-20(18)21/h2-9,12,21H,10-11,13-15H2,1H3,(H,27,36)(H,32,33)(H,28,34,35)

Synonyms: Fmoc-T-Aeg-OH; PNA T Monomer; Fmoc-U(5-Me)-Aeg-OH; Glycine, N-[(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]-; N-[2-(3,4-Dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; 2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)acetic acid

Fmoc-PNA-U-OH

Description: Fmoc-PNA-U-OH is a protected peptide nucleic acid (PNA) monomer used in the synthesis of peptide nucleic acids, offering specificity for adenine binding, stability against enzymatic degradation, and strong hybridization properties. It is widely used in genetic diagnostics, antisense therapy, and various molecular biology applications.

CAT: BRP-02047

CAS: 959151-70-3

MF: C25H24N4O7

MF: 492.48

Purity: ≥95%

Appearance: Solid

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Storage: Store at 2-8 °C

Density: 1.398±0.06 g/cm3

InChIKey: SSDDNBIJABMEDZ-UHFFFAOYSA-N

CanonicalSMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCN(CC(=O)O)C(=O)CN4C=CC(=O)NC4=O

IUPAC Name: 2-[[2-(2,4-dioxopyrimidin-1-yl)acetyl]-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]amino]acetic acid

InChI: InChI=1S/C25H24N4O7/c30-21-9-11-29(24(34)27-21)13-22(31)28(14-23(32)33)12-10-26-25(35)36-15-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-9,11,20H,10,12-15H2,(H,26,35)(H,32,33)(H,27,30,34)

Synonyms: N-[2-(3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; Fmoc-U-Aeg-OH; 2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamido)acetic acid

BOC-PNA-DAP(Z)-OH

Description: BOC-PNA-DAP(Z)-OH is a diaminopurine (DAP)-containing peptide nucleic acid (PNA) monomer that is protected with a BOC (tert-butoxycarbonyl) group at the N-terminus and has a benzyloxycarbonyl (Z) protection on the exocyclic amine group of diaminopurine. BOC-PNA-DAP(Z)-OH is a protected PNA monomer used in the synthesis of peptide nucleic acids, offering enhanced binding affinity for thymine or uracil, stability against enzymatic degradation, and strong hybridization properties. It is widely used in genetic diagnostics, antisense therapy, and various molecular biology applications where higher binding strength is advantageous.

CAT: BRP-02048

CAS: 202343-73-5

MF: C24H30N8O7

MF: 542.54

Purity: ≥95%

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Density: 1.43±0.1 g/cm3

InChIKey: FHGQSRLUXIVDFA-UHFFFAOYSA-N

CanonicalSMILES: CC(C)(C)OC(=O)NCCN(CC(=O)O)C(=O)CN1C=NC2=C(N=C(N=C21)N)NC(=O)OCC3=CC=CC=C3

IUPAC Name: 2-[[2-[2-amino-6-(phenylmethoxycarbonylamino)purin-9-yl]acetyl]-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethyl]amino]acetic acid

InChI: InChI=1S/C24H30N8O7/c1-24(2,3)39-22(36)26-9-10-31(12-17(34)35)16(33)11-32-14-27-18-19(28-21(25)30-20(18)32)29-23(37)38-13-15-7-5-4-6-8-15/h4-8,14H,9-13H2,1-3H3,(H,26,36)(H,34,35)(H3,25,28,29,30,37)

Synonyms: Boc-DAP(Z)-Aeg-OH; BOC-PNA-D(Z)-OH; Glycine, N-[[2-amino-6-[[(phenylmethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; N-[2-[2-Amino-6-[[(phenylmethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]glycine

BOC-PNA-thioU(PMB)-OH

Description: BOC-PNA-thioU(PMB)-OH is a protected peptide nucleic acid (PNA) monomer used in the synthesis of peptide nucleic acids, featuring thiouracil with a PMB protecting group for enhanced binding affinity to adenine. It provides stability against enzymatic degradation and strong hybridization properties, making it useful in genetic diagnostics, antisense therapy, and various molecular biology applications where higher binding strength and additional functionalization are advantageous.

CAT: BRP-02049

CAS: 253438-99-2

MF: C23H30N4O7S

MF: 506.57

Purity: ≥95%

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Density: 1.29±0.1 g/cm3

InChIKey: HDKCTBBIWSKCEV-UHFFFAOYSA-N

CanonicalSMILES: CC(C)(C)OC(=O)NCCN(CC(=O)O)C(=O)CN1C=CC(=O)N=C1SCC2=CC=C(C=C2)OC

IUPAC Name: 2-[[2-[2-[(4-methoxyphenyl)methylsulfanyl]-4-oxopyrimidin-1-yl]acetyl]-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethyl]amino]acetic acid

InChI: InChI=1S/C23H30N4O7S/c1-23(2,3)34-22(32)24-10-12-26(14-20(30)31)19(29)13-27-11-9-18(28)25-21(27)35-15-16-5-7-17(33-4)8-6-16/h5-9,11H,10,12-15H2,1-4H3,(H,24,32)(H,30,31)

Synonyms: BOC-PNA-thioU(PMB)-AEG-OH; Boc-thioU(PMB)-OH; BOC-PNA-S(Pmb)-OH; Glycine, N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-N-[[2-[[(4-methoxyphenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]acetyl]-; N-[2-[[(1,1-Dimethylethoxy)carbonyl]amino]ethyl]-N-[2-[2-[[(4-methoxyphenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]acetyl]glycine; N-(2-((tert-butoxycarbonyl)amino)ethyl)-N-(2-(2-((4-methoxybenzyl)thio)-4-oxopyrimidin-1(4H)-yl)acetyl)glycine

Fmoc-PNA-J(BOC)-OH

Description: Fmoc-PNA-J(BOC)-OH is a protected peptide nucleic acid (PNA) monomer used in the synthesis of peptide nucleic acids, featuring the synthetic J base with BOC protection for enhanced binding properties. It provides stability against enzymatic degradation and strong hybridization properties, making it useful in genetic diagnostics, antisense therapy, and various molecular biology applications where higher binding strength and additional functionalization are advantageous.

CAT: BRP-02050

CAS: 1095275-70-9

MF: C30H33N5O8

MF: 591.61

Purity: ≥95%

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Density: 1.37±0.1 g/cm3

InChIKey: HKYCYPRKFVETLD-UHFFFAOYSA-N

CanonicalSMILES: CC(C)(C)OC(=O)NC1=NC=C(C(=O)N1)CC(=O)N(CCNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)CC(=O)O

IUPAC Name: 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]-6-oxo-1H-pyrimidin-5-yl]acetyl]amino]acetic acid

InChI: InChI=1S/C30H33N5O8/c1-30(2,3)43-29(41)34-27-32-15-18(26(39)33-27)14-24(36)35(16-25(37)38)13-12-31-28(40)42-17-23-21-10-6-4-8-19(21)20-9-5-7-11-22(20)23/h4-11,15,23H,12-14,16-17H2,1-3H3,(H,31,40)(H,37,38)(H2,32,33,34,39,41)

Synonyms: Fmoc-J-(BOC)-AEG-OH; N-[2-[2-[[(1,1-Dimethylethoxy)carbonyl]amino]-1,6-dihydro-6-oxo-5-pyrimidinyl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(2-((tert-butoxycarbonyl)amino)-6-oxo-1,6-dihydropyrimidin-5-yl)acetyl)glycine; 2-[2-(2-{[(tert-butoxy)carbonyl]amino}-6-oxo-1,6-dihydropyrimidin-5-yl)-N-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]acetamido]acetic acid

BOC-PNA-J(Z)-OH

Description: BOC-PNA-J(Z)-OH is a protected peptide nucleic acid (PNA) monomer used in the synthesis of peptide nucleic acids, featuring the synthetic J base with Z protection for enhanced binding properties. It provides stability against enzymatic degradation and strong hybridization properties, making it useful in genetic diagnostics, antisense therapy, and various molecular biology applications where higher binding strength and additional functionalization are advantageous.

CAT: BRP-02051

CAS: 163081-03-6

MF: C23H29N5O8

MF: 503.51

Purity: ≥95%

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Density: 1.34±0.1 g/cm3

InChIKey: SNXJLIUIBYUYNG-UHFFFAOYSA-N

CanonicalSMILES: CC(C)(C)OC(=O)NCCN(CC(=O)O)C(=O)CC1=CN=C(NC1=O)NC(=O)OCC2=CC=CC=C2

IUPAC Name: 2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethyl-[2-[6-oxo-2-(phenylmethoxycarbonylamino)-1H-pyrimidin-5-yl]acetyl]amino]acetic acid

InChI: InChI=1S/C23H29N5O8/c1-23(2,3)36-21(33)24-9-10-28(13-18(30)31)17(29)11-16-12-25-20(26-19(16)32)27-22(34)35-14-15-7-5-4-6-8-15/h4-8,12H,9-11,13-14H2,1-3H3,(H,24,33)(H,30,31)(H2,25,26,27,32,34)

Synonyms: BOC-J(Z)-AEG-OH; Glycine, N-[[1,4-dihydro-4-oxo-2-[[(phenylmethoxy)carbonyl]amino]-5-pyrimidinyl]acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; N-(2-(2-(((benzyloxy)carbonyl)amino)-6-oxo-1,6-dihydropyrimidin-5-yl)acetyl)-N-(2-((tert-butoxycarbonyl)amino)ethyl)glycine

G-clamp PNA Monomer

Description: Guanidino-G-Clamp-PNA is a specialized type of peptide nucleic acid (PNA) modified with a guanidino group and a stabilizing clamp structure. This modification enhances its binding affinity, stability, and specificity when targeting complementary nucleic acid sequences. It finds applications in genetic diagnostics, therapeutics, and various research areas where precise nucleic acid targeting is essential.

CAT: BRP-02052

CAS: 476667-31-9

MF: C50H46N8O12

MF: 950.96

Purity: ≥95%

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Density: 1.42±0.1 g/cm3

InChIKey: AIWBXGLHDFKUCY-UHFFFAOYSA-N

CanonicalSMILES: C1=CC=C(C=C1)COC(=O)NC(=NCCOC2=CC=CC3=C2NC4=NC(=O)N(C=C4O3)CC(=O)N(CCNC(=O)OCC5C6=CC=CC=C6C7=CC=CC=C57)CC(=O)O)NC(=O)OCC8=CC=CC=C8

IUPAC Name: 2-[[2-[9-[2-[bis(phenylmethoxycarbonylamino)methylideneamino]ethoxy]-2-oxo-10H-pyrimido[5,4-b][1,4]benzoxazin-3-yl]acetyl]-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]amino]acetic acid

InChI: InChI=1S/C50H46N8O12/c59-42(57(28-43(60)61)24-22-52-48(63)69-31-38-36-18-9-7-16-34(36)35-17-8-10-19-37(35)38)27-58-26-41-45(54-47(58)62)53-44-39(20-11-21-40(44)70-41)66-25-23-51-46(55-49(64)67-29-32-12-3-1-4-13-32)56-50(65)68-30-33-14-5-2-6-15-33/h1-21,26,38H,22-25,27-31H2,(H,52,63)(H,60,61)(H,53,54,62)(H2,51,55,56,64,65)

Synonyms: Guanidino-G-Clamp-PNA; N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(9-(2-(2,3-bis((benzyloxy)carbonyl)guanidino)ethoxy)-2-oxo-2,10-dihydro-3H-benzo[b]pyrimido[4,5-e][1,4]oxazin-3-yl)acetyl)glycine; Glycine, N-[[9-[2-[[bis[[(phenylmethoxy)carbonyl]amino]methylene]amino]ethoxy]-1,2-dihydro-2-oxo-3H-pyrimido[5,4-b][1,4]benzoxazin-3-yl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]-

Fmoc-PNA-A(Boc)-OH

Description: Fmoc-PNA-A(Boc)-OH is a synthetic peptide nucleic acid (PNA) modified with Fmoc and Boc protecting groups, designed for precise synthesis and specific hybridization with complementary DNA or RNA sequences. It serves as a versatile tool in molecular biology and biomedical research, offering high specificity and stability in nucleic acid interactions.

CAT: BRP-02053

CAS: 511534-99-9

MF: C31H33N7O7

MF: 615.64

Purity: ≥95%

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Density: 1.41±0.1 g/cm3

InChIKey: CQFVUKSSRZPFKA-UHFFFAOYSA-N

CanonicalSMILES: CC(C)(C)OC(=O)NC1=C2C(=NC=N1)N(C=N2)CC(=O)N(CCNC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)CC(=O)O

IUPAC Name: 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl-[2-[6-[(2-methylpropan-2-yl)oxycarbonylamino]purin-9-yl]acetyl]amino]acetic acid

InChI: InChI=1S/C31H33N7O7/c1-31(2,3)45-30(43)36-27-26-28(34-17-33-27)38(18-35-26)14-24(39)37(15-25(40)41)13-12-32-29(42)44-16-23-21-10-6-4-8-19(21)20-9-5-7-11-22(20)23/h4-11,17-18,23H,12-16H2,1-3H3,(H,32,42)(H,40,41)(H,33,34,36,43)

Synonyms: Glycine, N-[[6-[[(1,1-dimethylethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]-; N-[2-[6-[[(1,1-Dimethylethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(6-((tert-butoxycarbonyl)amino)-9H-purin-9-yl)acetyl)glycine

Fmoc-PNA-C(Boc)-OH

Description: Fmoc-PNA-C(Boc)-OH is a synthetic peptide nucleic acid (PNA) modified with Fmoc and Boc protecting groups, designed for controlled synthesis and specific binding to complementary DNA or RNA sequences. It serves as a valuable tool in molecular biology, offering high specificity and stability in nucleic acid interactions and applications ranging from basic research to diagnostics and therapeutic development.

CAT: BRP-02054

CAS: 172405-61-7

MF: C30H33N5O8

MF: 591.61

Purity: ≥95%

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Density: 1.35±0.1 g/cm3

InChIKey: XTXTTZCNVKRDDX-UHFFFAOYSA-N

CanonicalSMILES: CC(C)(C)OC(=O)NC1=NC(=O)N(C=C1)CC(=O)N(CCNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)CC(=O)O

IUPAC Name: 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl-[2-[4-[(2-methylpropan-2-yl)oxycarbonylamino]-2-oxopyrimidin-1-yl]acetyl]amino]acetic acid

InChI: InChI=1S/C30H33N5O8/c1-30(2,3)43-29(41)33-24-12-14-35(27(39)32-24)16-25(36)34(17-26(37)38)15-13-31-28(40)42-18-23-21-10-6-4-8-19(21)20-9-5-7-11-22(20)23/h4-12,14,23H,13,15-18H2,1-3H3,(H,31,40)(H,37,38)(H,32,33,39,41)

Synonyms: Glycine, N-[[4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-1(2H)-pyrimidinyl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]-; N-[2-[4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-oxo-1(2H)-pyrimidinyl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(4-((tert-butoxycarbonyl)amino)-2-oxopyrimidin-1(2H)-yl)acetyl)glycine

Fmoc-PNA-G(Boc)-OH

Description: Fmoc-PNA-G(Boc)-OH is a synthetic peptide nucleic acid (PNA) modified with Fmoc and Boc protecting groups, designed for precise synthesis and targeted binding to complementary DNA or RNA sequences. It serves as a versatile tool in molecular biology, offering robustness, specificity, and applicability across various research and diagnostic fields.

CAT: BRP-02055

CAS: 1052677-90-3

MF: C31H33N7O8

MF: 631.64

Purity: ≥95%

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Density: 1.46±0.1 g/cm3

InChIKey: JVIAXIMEDXKTSN-UHFFFAOYSA-N

CanonicalSMILES: CC(C)(C)OC(=O)NC1=NC2=C(C(=O)N1)N=CN2CC(=O)N(CCNC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)CC(=O)O

IUPAC Name: 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]-6-oxo-1H-purin-9-yl]acetyl]amino]acetic acid

InChI: InChI=1S/C31H33N7O8/c1-31(2,3)46-30(44)36-28-34-26-25(27(42)35-28)33-17-38(26)14-23(39)37(15-24(40)41)13-12-32-29(43)45-16-22-20-10-6-4-8-18(20)19-9-5-7-11-21(19)22/h4-11,17,22H,12-16H2,1-3H3,(H,32,43)(H,40,41)(H2,34,35,36,42,44)

Synonyms: N-[2-[2-[[(1,1-Dimethylethoxy)carbonyl]amino]-1,6-dihydro-6-oxo-9H-purin-9-yl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(2-((tert-butoxycarbonyl)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)acetyl)glycine; 2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(2-((tert-butoxycarbonyl)amino)-6-oxo-1H-purin-9(6H)-yl)acetamido)acetic acid

Boc-PNA-U-OH

Description: Boc-PNA-U-OH is a synthetic peptide nucleic acid (PNA) modified with the Boc protecting group, designed for controlled synthesis and targeted binding to complementary DNA or RNA sequences. It serves as a versatile tool in molecular biology research, offering high specificity and utility across various applications in gene regulation, diagnostics, and nucleic acid research.

CAT: BRP-02056

CAS: 149500-74-3

MF: C15H22N4O7

MF: 370.36

Purity: ≥95%

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Density: 1.335±0.06 g/cm3

Melting Point: 164-170 °C

InChIKey: ZPRZPMGSCWEHKC-UHFFFAOYSA-N

CanonicalSMILES: O=C(OC(C)(C)C)NCCN(C(=O)CN1C=CC(=O)NC1=O)CC(=O)O

IUPAC Name: N-(2-((tert-butoxycarbonyl)amino)ethyl)-N-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetyl)glycine

InChI: InChI=1S/C15H22N4O7/c1-15(2,3)26-14(25)16-5-7-18(9-12(22)23)11(21)8-19-6-4-10(20)17-13(19)24/h4,6H,5,7-9H2,1-3H3,(H,16,25)(H,22,23)(H,17,20,24)

Synonyms: Glycine, N-[(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; N-[2-(3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]glycine

Boc-PNA-M(Z)-OH

Description: Boc-PNA-M(Z)-OH is a PNA monomer with a Boc protecting group on the terminal amine and a Cbz protecting group on the modified base. It is used in the synthesis of peptide nucleic acids (PNAs). The Boc group facilitates solid-phase synthesis by protecting the amine group, while the Z group protects the base during chemical reactions.

CAT: BRP-02057

MF: C24H30N4O7

MF: 486.53

Purity: ≥95%

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InChIKey: CXZDUTOZNUXMQC-UHFFFAOYSA-N

CanonicalSMILES: O=C(O)CN(C(CC1=CC=C(NC(OCC2=CC=CC=C2)=O)N=C1)=O)CCNC(OC(C)(C)C)=O

IUPAC Name: N-(2-(6-(((benzyloxy)carbonyl)amino)pyridin-3-yl)acetyl)-N-(2-((tert-butoxycarbonyl)amino)ethyl)glycine

InChI: InChI=1S/C24H30N4O7/c1-24(2,3)35-22(32)25-11-12-28(15-21(30)31)20(29)13-18-9-10-19(26-14-18)27-23(33)34-16-17-7-5-4-6-8-17/h4-10,14H,11-13,15-16H2,1-3H3,(H,25,32)(H,30,31)(H,26,27,33)

Fmoc-PNA-M(Bhoc)-OH

Description: Fmoc-PNA-M(Bhoc)-OH is a PNA monomer with an Fmoc protecting group on the terminal amine, and a Bhoc protecting group on the modified base. It is used in the synthesis of peptide nucleic acids (PNAs) which are synthetic analogs of DNA and RNA. The Fmoc group allows for solid-phase synthesis, while the Bhoc group protects the base during chemical reactions.

CAT: BRP-02058

MF: C40H36N4O7

MF: 684.75

Purity: ≥95%

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InChIKey: ZVLCJMSLDDKFKX-UHFFFAOYSA-N

CanonicalSMILES: O=C(O)CN(C(CC1=CC=C(NC(OC(C2=CC=CC=C2)C3=CC=CC=C3)=O)N=C1)=O)CCNC(OCC4C5=C(C=CC=C5)C6=C4C=CC=C6)=O

IUPAC Name: N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(6-(((benzhydryloxy)carbonyl)amino)pyridin-3-yl)acetyl)glycine

InChI: InChI=1S/C40H36N4O7/c45-36(23-27-19-20-35(42-24-27)43-40(49)51-38(28-11-3-1-4-12-28)29-13-5-2-6-14-29)44(25-37(46)47)22-21-41-39(48)50-26-34-32-17-9-7-15-30(32)31-16-8-10-18-33(31)34/h1-20,24,34,38H,21-23,25-26H2,(H,41,48)(H,46,47)(H,42,43,49)

Fmoc-PNA-M(Boc)-OH

Description: Fmoc-PNA-M(Boc)-OH is a PNA monomer with an Fmoc protecting group on the terminal amine and a Boc protecting group on the modified base. It is used in the synthesis of peptide nucleic acids (PNAs). The Fmoc group facilitates solid-phase synthesis by protecting the amine group, while the Boc group protects the base during chemical reactions.

CAT: BRP-02059

CAS: 1417611-27-8

MF: C31H34N4O7

MF: 574.62

Purity: ≥95%

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Density: 1.308±0.06 g/cm3

Boiling Point: 781.3±60.0 °C at 760 mmHg

InChIKey: KKGJHNNYUDROSA-UHFFFAOYSA-N

CanonicalSMILES: CC(C)(C)OC(=O)NC1=NC=C(C=C1)CC(=O)N(CCNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)CC(=O)O

IUPAC Name: 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl-[2-[6-[(2-methylpropan-2-yl)oxycarbonylamino]pyridin-3-yl]acetyl]amino]acetic acid

InChI: InChI=1S/C31H34N4O7/c1-31(2,3)42-30(40)34-26-13-12-20(17-33-26)16-27(36)35(18-28(37)38)15-14-32-29(39)41-19-25-23-10-6-4-8-21(23)22-9-5-7-11-24(22)25/h4-13,17,25H,14-16,18-19H2,1-3H3,(H,32,39)(H,37,38)(H,33,34,40)

Synonyms: 2-(N-(2-(Fmoc)ethyl)-2-(6-(tert-butoxycarbonylamino)pyridin-3-yl)acetamido)acetic acid; N-[2-[6-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-pyridinyl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(6-((tert-butoxycarbonyl)amino)pyridin-3-yl)acetyl)glycine

Fmoc-PNA-J(Bhoc)-OH

Description: Fmoc-PNA-J(Bhoc)-OH is a PNA monomer used in the synthesis of peptide nucleic acids (PNAs). It features an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group on the terminal amine and a Bhoc (benzyloxycarbonyl) protecting group on the modified base J. These protecting groups facilitate solid-phase synthesis, ensuring the integrity of the monomer and preventing unwanted side reactions during the assembly of PNA sequences.

CAT: BRP-02060

MF: C39H35N5O8

MF: 701.74

Purity: ≥95%

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InChIKey: AXTIXKVVQRPTAF-UHFFFAOYSA-N

CanonicalSMILES: O=C(O)CN(CCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(CC4=CN=C(NC(OC(C5=CC=CC=C5)C6=CC=CC=C6)=O)NC4=O)=O

IUPAC Name: N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(2-(((benzhydryloxy)carbonyl)amino)-6-oxo-1,6-dihydropyrimidin-5-yl)acetyl)glycine

InChI: InChI=1S/C39H35N5O8/c45-33(21-27-22-41-37(42-36(27)48)43-39(50)52-35(25-11-3-1-4-12-25)26-13-5-2-6-14-26)44(23-34(46)47)20-19-40-38(49)51-24-32-30-17-9-7-15-28(30)29-16-8-10-18-31(29)32/h1-18,22,32,35H,19-21,23-24H2,(H,40,49)(H,46,47)(H2,41,42,43,48,50)

Fmoc-PNA-D(tetraBhoc)-OH

Description: Fmoc-PNA-D(tetraBhoc)-OH is a peptide nucleic acid (PNA) monomer used in the synthesis of PNAs. It features an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group on the terminal amine and tetraBhoc (tetra benzyloxycarbonyl) protecting groups on the modified base D. These protecting groups are essential for solid-phase synthesis, ensuring that the monomer remains stable and reactive only at the desired stages of the assembly process. This monomer is particularly useful for creating PNAs with specific binding properties and enhanced stability.

CAT: BRP-02061

MF: C82H66N8O13

MF: 1371.47

Purity: ≥95%

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InChIKey: JQBRHDKMTRBGAE-UHFFFAOYSA-N

CanonicalSMILES: O=C(O)CN(CCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)C(CN4C=NC5=C4N=C(N(C(OC(C6=CC=CC=C6)C7=CC=CC=C7)=O)C(OC(C8=CC=CC=C8)C9=CC=CC=C9)=O)N=C5N(C(OC(C%10=CC=CC=C%10)C%11=CC=CC=C%11)=O)C(OC(C%12=CC=CC=C%12)C%13=CC=CC=C%13)=O)=O

IUPAC Name: N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(2,6-bis(bis((benzhydryloxy)carbonyl)amino)-9H-purin-9-yl)acetyl)glycine

InChI: InChI=1S/C82H66N8O13/c91-68(87(52-69(92)93)50-49-83-78(94)99-53-67-65-47-27-25-45-63(65)64-46-26-28-48-66(64)67)51-88-54-84-70-75(88)85-77(90(81(97)102-73(59-37-17-5-18-38-59)60-39-19-6-20-40-60)82(98)103-74(61-41-21-7-22-42-61)62-43-23-8-24-44-62)86-76(70)89(79(95)100-71(55-29-9-1-10-30-55)56-31-11-2-12-32-56)80(96)101-72(57-33-13-3-14-34-57)58-35-15-4-16-36-58/h1-48,54,67,71-74H,49-53H2,(H,83,94)(H,92,93)

Fmoc-PNA-D(tetraBoc)-OH

Description: Fmoc-PNA-D(tetraBoc)-OH is a peptide nucleic acid (PNA) monomer used in the synthesis of PNA oligomers. It features an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group on the terminal amine and tetraBoc (tetra tert-butoxycarbonyl) protecting groups on the modified base D. These protecting groups help maintain the integrity of the monomer during the solid-phase synthesis process, allowing for precise and controlled assembly of PNA sequences. This monomer is valuable for creating PNAs with tailored binding characteristics and increased stability for various biochemical applications.

CAT: BRP-02062

CAS: 2101661-88-3

MF: C46H58N8O13

MF: 931.00

Purity: ≥95%

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Density: 1.30±0.1 g/cm3

InChIKey: FNWBHNGZUCVYGL-UHFFFAOYSA-N

CanonicalSMILES: CC(C)(C)OC(=O)N(C1=NC(=NC2=C1N=CN2CC(=O)N(CCNC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)CC(=O)O)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

IUPAC Name: 2-[[2-[2,6-bis[bis[(2-methylpropan-2-yl)oxycarbonyl]amino]purin-9-yl]acetyl]-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]amino]acetic acid

InChI: InChI=1S/C46H58N8O13/c1-43(2,3)64-39(59)53(40(60)65-44(4,5)6)36-34-35(49-37(50-36)54(41(61)66-45(7,8)9)42(62)67-46(10,11)12)52(26-48-34)23-32(55)51(24-33(56)57)22-21-47-38(58)63-25-31-29-19-15-13-17-27(29)28-18-14-16-20-30(28)31/h13-20,26,31H,21-25H2,1-12H3,(H,47,58)(H,56,57)

Synonyms: 2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(2,6-bis(bis(tert-butoxycarbonyl)amino)-9H-purin-9-yl)acetamido)acetic acid; N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(2,6-bis(bis(tert-butoxycarbonyl)amino)-9H-purin-9-yl)acetyl)glycine; 2-{2-[2,6-bis({bis[(tert-butoxy)carbonyl]amino})-9H-purin-9-yl]-N-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]acetamido}acetic acid