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2'-Modified Phosphoramidites
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Cyanine 5.5 Phosphoramidite (BRP-02236)
Description: Cyanine 5.5 Phosphoramidite is a fluorescent dye used for oligonucleotide labeling.
CAT: BRP-02236
CAS: 916753-58-7
Molecular Formula: C68H76IN4O4P
Molecular Weight: 1171.24
Purity: ≥95%
Appearance: Blue Solid
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Storage: Store at -20 °C
Symbol: Cy5.5 Phosphoramidite
InChIKey: HUHDLWQCBHNBPG-UHFFFAOYSA-M
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC[N+]1=C(C(C2=C1C=CC3=CC=CC=C32)(C)C)C=CC=CC=C4C(C5=C(N4CCCOC(C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=C(C=C8)OC)C=CC9=CC=CC=C95)(C)C)OCCC#N.[I-]
IUPAC Name: 3-[[di(propan-2-yl)amino]-[3-[2-[5-[3-[3-[(4-methoxyphenyl)-diphenylmethoxy]propyl]-1,1-dimethylbenzo[e]indol-2-ylidene]penta-1,3-dienyl]-1,1-dimethylbenzo[e]indol-3-ium-3-yl]propoxy]phosphanyl]oxypropanenitrile;iodide
InChI: InChI=1S/C68H76N4O4P.HI/c1-50(2)72(51(3)4)77(75-48-23-44-69)76-49-25-46-71-61-43-37-53-27-20-22-33-59(53)65(61)67(7,8)63(71)35-18-12-17-34-62-66(5,6)64-58-32-21-19-26-52(58)36-42-60(64)70(62)45-24-47-74-68(54-28-13-10-14-29-54,55-30-15-11-16-31-55)56-38-40-57(73-9)41-39-56;/h10-22,26-43,50-51H,23-25,45-49H2,1-9H3;1H/q+1;/p-1
Synonyms: 1-[3-(4-monomethoxytrityloxy)propyl]-1'-[3-[(2-cyanoethyl)-(N,N-diisopropyl)phosphoramidityl]propyl]-3,3,3',3'-tetramethyl-4,5-benzindodicarbocyanine iodide; 1H-Benz[e]indolium, 2-[5-[3-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-1,1-dimethyl-2H-benz[e]indol-2-ylidene]-1,3-pentadien-1-yl]-3-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-1,1-dimethyl-, iodide (1:1); Cy5.5 Phosphoramidite
Related CAS: 791569-89-6 (free base)
6-JOE phosphoramidite (BRP-02237)
Description: 6-JOE phosphoramidite is a fluorescent dye used for oligonucleotide labeling.
CAT: BRP-02237
Molecular Formula: C48H60Cl2N3O12P
Molecular Weight: 972.88
Purity: ≥95%
Appearance: White solid
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Storage: Store at -20 °C
InChIKey: CKBMUCQWGUZAKQ-UHFFFAOYSA-N
Fluorescence Maximum: 554
Absorption Maximum (Lambda Max): 533
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)C1=CC2=C(C=C1)C(=O)OC23C4=CC(=C(C(=C4OC5=C(C(=C(C=C35)OC)OC(=O)C(C)(C)C)Cl)Cl)OC(=O)C(C)(C)C)OC)OCCC#N
IUPAC Name: [4',5'-dichloro-6-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-2',7'-dimethoxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C48H60Cl2N3O12P/c1-27(2)53(28(3)4)66(61-23-17-20-51)60-22-16-14-13-15-21-52-42(54)29-18-19-30-31(24-29)48(65-43(30)55)32-25-34(58-11)40(63-44(56)46(5,6)7)36(49)38(32)62-39-33(48)26-35(59-12)41(37(39)50)64-45(57)47(8,9)10/h18-19,24-28H,13-17,21-23H2,1-12H3,(H,52,54)
Synonyms: 6-(4',5'-Dichloro-2',7'-dimethoxy-3',6'-dipivaloylfluorescein-6-carboxamido)-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 5'-Dichloro-dimethoxy-Fluorescein Phosphoramidite II (Joe II); JOE phosphoramidite, 6-isomer; 5-Carboxy-2',7'-dimethoxy-4',5'-dichloro-fluoresceinamide phosphoramidite; 4',5'-dichloro-6-((6-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)hexyl)carbamoyl)-2',7'-dimethoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)
TAMRA-dT phosphoramidite (BRP-02238)
Description: TAMRA-dT phosphoramidite is a fluorescent dye used for oligonucleotide labeling.
CAT: BRP-02238
CAS: 1266091-48-8
Molecular Formula: C73H83N8O13P
Molecular Weight: 1311.48
Purity: >95%
Appearance: Red glass
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Storage: Store at -20 °C, Keep in a dark and dry place
Symbol: TAMRA-dT
InChIKey: LQNDGVJBXVJPAT-FQPLGIQNSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C=CC(=O)NCCCCCCNC(=O)C6=CC(=C(C=C6)C(=O)[O-])C7=C8C=CC(=[N+](C)C)C=C8OC9=C7C=CC(=C9)N(C)C
IUPAC Name: 4-[6-[[3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoyl]amino]hexylcarbamoyl]-2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]benzoate
InChI: InChI=1S/C73H83N8O13P/c1-47(2)81(48(3)4)95(91-40-18-37-74)94-64-44-67(93-65(64)46-90-73(51-19-14-13-15-20-51,52-23-29-56(88-9)30-24-52)53-25-31-57(89-10)32-26-53)80-45-50(70(84)77-72(80)87)22-36-66(82)75-38-16-11-12-17-39-76-69(83)49-21-33-58(71(85)86)61(41-49)68-59-34-27-54(78(5)6)42-62(59)92-63-43-55(79(7)8)28-35-60(63)68/h13-15,19-36,41-43,45,47-48,64-65,67H,11-12,16-18,38-40,44,46H2,1-10H3,(H3-,75,76,77,82,83,84,85,86,87)/b36-22+/t64-,65+,67+,95?/m0/s1
Synonyms: 5'-Dimethoxytrityloxy-5-[N-((tetramethylrhodaminyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Xanthylium, 9-[5-[[[6-[[3-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-1-oxo-2-propen-1-yl]amino]hexyl]amino]carbonyl]-2-carboxyphenyl]-3,6-bis(dimethylamino)-, inner salt; 4-((6-(3-(1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylamido)hexyl)carbamoyl)-2-(6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl)benzoate
6-TAMRA phosphoramidite (BRP-02239)
Description: Oligonucleotides modified with TAMRA derivatives can be used for genomic research, molecular diagnosis, and molecular biology.
CAT: BRP-02239
Molecular Formula: C66H77N6O10P
Molecular Weight: 1145.35
Purity: >95%
Appearance: Dark red solid
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Storage: Store at -20 °C
Symbol: 5'-TAMRA phosphoramidite (6-TAMRA)
InChIKey: VDRDQKBQFCBCQK-FYICZBFESA-N
Solubility: Soluble in acetonitrile, DCM
IUPAC Name: (3R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-1-(6-(3',6'-bis(dimethylamino)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxamido)hexanoyl)pyrrolidin-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C66H77N6O10P/c1-44(2)72(45(3)4)83(79-37-17-35-67)82-55-39-52(43-78-65(47-18-13-11-14-19-47,48-22-28-53(76-9)29-23-48)49-24-30-54(77-10)31-25-49)71(42-55)62(73)20-15-12-16-36-68-63(74)46-21-32-56-59(38-46)66(81-64(56)75)57-33-26-50(69(5)6)40-60(57)80-61-41-51(70(7)8)27-34-58(61)66/h11,13-14,18-19,21-34,38,40-41,44-45,52,55H,12,15-17,20,36-37,39,42-43H2,1-10H3,(H,68,74)/t52-,55+,83?/m0/s1
Synonyms: TAMRA phosphoramidite, 6-isomer; N-(6-oxo-6-[(3R,5S)-5-[(4,4'-dimethoxytrityl)-oxymethyl]-3-(N,N-diisopropylamino-2-cyanoethoxyphosphin-oxy)pyrrolidine-1-yl]hexyl)-3',6'-Bis(dimethylamino)-3-oxo-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-yl-carboxamide
6-Fluorescein phosphoramidite (BRP-02240)
Description: 6-Fluorescein phosphoramidite is prepared from 6-carboxyfluorescein derivatives and does not contain 4,4'-dimethoxytrityl (DMT) groups. It can only be added once at the 5'end to terminate the synthesis.
CAT: BRP-02240
CAS: 204697-37-0
Molecular Formula: C46H58N3O10P
Molecular Weight: 843.94
Purity: ≥90%
Appearance: White to Off-white Solid
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Storage: Store at -20 °C
Boiling Point: 850.6±65.0°C at 760 mmHg
Symbol: 6-FAM
InChIKey: MGPYJVWEJNTXLC-UHFFFAOYSA-N
Solubility: Soluble in Acetonitrile, DCM
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)C1=CC2=C(C=C1)C(=O)OC23C4=C(C=C(C=C4)OC(=O)C(C)(C)C)OC5=C3C=CC(=C5)OC(=O)C(C)(C)C)OCCC#N
IUPAC Name: [6-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C46H58N3O10P/c1-29(2)49(30(3)4)60(55-25-15-22-47)54-24-14-12-11-13-23-48-40(50)31-16-19-34-37(26-31)46(59-41(34)51)35-20-17-32(56-42(52)44(5,6)7)27-38(35)58-39-28-33(18-21-36(39)46)57-43(53)45(8,9)10/h16-21,26-30H,11-15,23-25H2,1-10H3,(H,48,50)
Synonyms: FAM Phosphoramidite, 6-Isomer; 6-FAM phosphoramidite; FAM phosphoramidite, 6-isomer; DyLight FAM-6 CEP; 5'(6)-FAM; 5'-6-Fluorescein phosphoramidite; 6-((6-(((2-Cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)hexyl)carbamoyl)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)
-ce-phosphoramidite.gif)
5'-VP-2'-OMe-G(iBu)-CE-Phosphoramidite
Description: 5'-VP-2'-OMe-G(iBu)-CE-Phosphoramidite is a reagent used in the solid-phase synthesis of RNA oligonucleotides for incorporating 2'-O-methylguanosine (G) residues. It features a 5'-VP (Vented Protective group) for protection during synthesis, a 2'-O-methyl modification on the guanine ribose to enhance RNA stability, and an isobutyryl (iBu) group protecting the exocyclic amino group of guanine. The reagent also includes a cyanoethyl (CE) phosphoramidite group, which facilitates the coupling of nucleotides during the synthesis process. This configuration is commonly used to create RNA sequences with enhanced resistance to enzymatic degradation, making it ideal for therapeutic and diagnostic applications.
CAT: BRP-02346
Molecular Formula: C37H59N7O13P2
Molecular Weight: 871.86
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: BVJBAQGYDLYVPP-UYDHQHTBSA-N
CanonicalSMILES: N#CCCOP(OC1C(OC(N2C=NC=3C(=O)N=C(NC(=O)C(C)C)NC32)C1OC)C=CP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)N(C(C)C)C(C)C
IUPAC Name: (((2-((2R,3R,4R,5R)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-methoxytetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)
InChI: InChI=1S/C37H59N7O13P2/c1-22(2)30(45)41-35-40-29-26(31(46)42-35)39-19-43(29)32-28(50-13)27(57-58(53-17-14-16-38)44(23(3)4)24(5)6)25(56-32)15-18-59(49,54-20-51-33(47)36(7,8)9)55-21-52-34(48)37(10,11)12/h15,18-19,22-25,27-28,32H,14,17,20-21H2,1-13H3,(H2,40,41,42,45,46)/t25-,27-,28-,32-,58?/m1/s1
Synonyms: 5'-POM-vinyl phosphonate-2'-O-Me-rG(iBu)-3'-CE-Phosphoramidite; 5'-VP-2'-OMe-G(iBu)-3'-CE-Phoshoramidite; 5'-POM-vinyl phosphonate-2'-OMe-G(iBu)-CE-Phosphoramidite
-ce-phosphoramidite.gif)
5'-VP-2'-OMe-C(Ac)-CE-Phosphoramidite
Description: 5'-VP-2'-OMe-C(Ac)-CE-Phosphoramidite is a reagent used in the solid-phase synthesis of RNA oligonucleotides for incorporating 2'-O-methylcytidine (C) residues. It features a 5'-VP (Vented Protective) group for safeguarding the 5' end during synthesis, a 2'-O-methyl modification on the cytidine ribose to enhance the stability and resistance of the RNA to enzymatic degradation, and an acetyl (Ac) group protecting the exocyclic amino group of cytidine. The cyanoethyl (CE) phosphoramidite group facilitates the coupling of nucleotides during the synthesis process. This reagent is particularly useful for creating stable RNA sequences, often used in therapeutic and diagnostic applications.
CAT: BRP-02347
Molecular Formula: C34H55N5O13P2
Molecular Weight: 803.78
Purity: ≥98%
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Storage: Store at -20 °C
InChIKey: IHTFJGAKRRVDIF-VFAGAGMZSA-N
IUPAC Name: (((2-((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-4-methoxytetrahydrofuran-2-yl)vinyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)
InChI: InChI=1S/C34H55N5O13P2/c1-22(2)39(23(3)4)53(48-18-13-16-35)52-27-25(51-29(28(27)45-12)38-17-14-26(36-24(5)40)37-32(38)43)15-19-54(44,49-20-46-30(41)33(6,7)8)50-21-47-31(42)34(9,10)11/h14-15,17,19,22-23,25,27-29H,13,18,20-21H2,1-12H3,(H,36,37,40,43)/t25-,27-,28-,29-,53?/m1/s1
Synonyms: 5'-POM-vinyl phosphonate-2'-O-Me-rC(Ac)-3'-CE-Phosphoramidite; 5'-POM-vinyl phosphonate-2'-OMe-C(Ac)-CE-Phosphoramidite; 5'-VP-2'-OMe-C(Ac)-3'-CE-Phosphoramidite
FAM-dT Phosphoramidite
Description: FAM-dT phosphoramidite is a conjugate of deoxythymidine phosphoramidite and 6-isomer of FAM.
CAT: BRP-02348
CAS: 637330-26-8
Molecular Formula: C79H87N6O17P
Molecular Weight: 1423.54
Appearance: Off White Powder
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Storage: Store at -20 °C
InChIKey: FVVPPYBKLBLXEK-FLDIZLHUSA-N
Solubility: Soluble in in acetonitrile, DCM
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C#CCNC(=O)CCCCCNC(=O)C6=CC7=C(C=C6)C(=O)OC78C9=C(C=C(C=C9)OC(=O)C(C)(C)C)OC1=C8C=CC(=C1)OC(=O)C(C)(C)C
IUPAC Name: [6-[[6-[3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-ynylamino]-6-oxohexyl]carbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C79H87N6O17P/c1-49(2)85(50(3)4)103(96-42-20-39-80)102-66-46-69(100-67(66)48-95-78(53-22-15-13-16-23-53,54-26-30-56(93-11)31-27-54)55-28-32-57(94-12)33-29-55)84-47-52(71(88)83-75(84)92)21-19-41-81-68(86)24-17-14-18-40-82-70(87)51-25-36-60-63(43-51)79(101-72(60)89)61-37-34-58(97-73(90)76(5,6)7)44-64(61)99-65-45-59(35-38-62(65)79)98-74(91)77(8,9)10/h13,15-16,22-23,25-38,43-45,47,49-50,66-67,69H,14,17-18,20,24,40-42,46,48H2,1-12H3,(H,81,86)(H,82,87)(H,83,88,92)/t66-,67+,69+,103?/m0/s1
Synonyms: 6-((6-((3-(1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)prop-2-yn-1-yl)amino)-6-oxohexyl)carbamoyl)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate); Uridine, 5-[3-[[6-[[[3',6'-bis(2,2-dimethyl-1-oxopropoxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl]carbonyl]amino]-1-oxohexyl]amino]-1-propynyl]-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
6-Fluorescein dT phosphoramidite
Description: 6-Fluorescein dT phosphoramidite can be inserted into the desired sequence as a replacement for a dT residue during oligonucleotides synthesis.
CAT: BRP-02349
CAS: 1194507-30-6
Molecular Formula: C79H89N6O17P
Molecular Weight: 1425.56
Purity: ≥95%
Appearance: Off-white Solid
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Storage: Store at 2-8 °C
InChIKey: CADOGPWQRZBAGJ-FLDIZLHUSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: N#CCCOP(OC1CC(OC1COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C=C(C=CC(=O)NCCCCCCNC(=O)C6=CC=C7C(=O)OC8(C9=CC=C(OC(=O)C(C)(C)C)C=C9OC%10=CC(OC(=O)C(C)(C)C)=CC=C%108)C7=C6)C(=O)NC5=O)N(C(C)C)C(C)C
IUPAC Name: 6-((6-(3-(1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylamido)hexyl)carbamoyl)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)
InChI: InChI=1S/C79H89N6O17P/c1-49(2)85(50(3)4)103(96-42-20-39-80)102-66-46-69(100-67(66)48-95-78(53-21-16-15-17-22-53,54-25-29-56(93-11)30-26-54)55-27-31-57(94-12)32-28-55)84-47-52(71(88)83-75(84)92)24-38-68(86)81-40-18-13-14-19-41-82-70(87)51-23-35-60-63(43-51)79(101-72(60)89)61-36-33-58(97-73(90)76(5,6)7)44-64(61)99-65-45-59(34-37-62(65)79)98-74(91)77(8,9)10/h15-17,21-38,43-45,47,49-50,66-67,69H,13-14,18-20,40-42,46,48H2,1-12H3,(H,81,86)(H,82,87)(H,83,88,92)/t66-,67+,69+,103?/m0/s1
Synonyms: Uridine, 5-[3-[[6-[[[3',6'-bis(2,2-dimethyl-1-oxopropoxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl]carbonyl]amino]hexyl]amino]-3-oxo-1-propen-1-yl]-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-Dimethoxytrityloxy-5-[N-((3',6'-dipivaloylfluoresceinyl)-aminohexyl)-3-acrylimido]-2'-deoxyuridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Fluorescein-dT Phosphoramidite; Fluorescein dT CEP; 6-FAM-dT Phosphoramidite
HEX-dT Phosphoramidite
Description: HEX-dT phosphoramidite contains a DMT group to allow quantification of coupling. It can be inserted into a target sequence as a replacement for a dT residue. It provides a valuable tool to add the HEX tag to a desired location of an oligo sequence. It is complimentary to the commonly used 6-HEX phosphoramidite that contains no DMT group and can only be added at the 5'-terminus, thus terminating synthesis.
CAT: BRP-02350
Molecular Formula: C79H83Cl6N6O17P
Molecular Weight: 1632.23
Appearance: Solid
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Storage: Store at -20 °C
InChIKey: PYHVUSJUSKKCHB-YNKBEQGLSA-N
IUPAC Name: 6-((6-(3-(1-((2R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylamido)hexyl)carbamoyl)-2',4,4',5',7,7'-hexachloro-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)
InChI: InChI=1S/C79H83Cl6N6O17P/c1-43(2)91(44(3)4)109(102-36-20-33-86)108-57-40-60(103-58(57)42-101-78(46-21-16-15-17-22-46,47-24-28-49(99-11)29-25-47)48-26-30-50(100-12)31-27-48)90-41-45(70(93)89-75(90)98)23-32-59(92)87-34-18-13-14-19-35-88-71(94)51-37-54(80)61-62(63(51)83)79(107-72(61)95)52-38-55(81)68(105-73(96)76(5,6)7)64(84)66(52)104-67-53(79)39-56(82)69(65(67)85)106-74(97)77(8,9)10/h15-17,21-32,37-39,41,43-44,57-58,60H,13-14,18-20,34-36,40,42H2,1-12H3,(H,87,92)(H,88,94)(H,89,93,98)/t57-,58+,60+,109?/m0/s1
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SIMA (HEX)-dT Phosphoramidite
Description: SIMA (HEX)-dT Phosphoramidite embodies an exquisite chemical reagent, which, when employed in the synthesis of oligonucleotides, brings forth labeling with fluorescent prowess. This sky-high labeling capacity, what with its hexachlorofluorescein (HEX) dye and the thymidine base, can be ushered into diverse biomedical applications, including the fluoroescence in situ hybridization (FISH), DNA sequencing and detecting specific genetic mutations or diseases.
CAT: BRP-02351
Molecular Formula: C91H95Cl2N6O17P
Molecular Weight: 1646.64
Purity: ≥95%
Appearance: White powder
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Storage: Store at -20 °C
InChIKey: KPIIJRDTWQIEJL-WLPPFOLSSA-N
Solubility: Soluble in Anhydrous Acetonitrile, DCM
IUPAC Name: 6-((6-((3-(1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)allyl)amino)-6-oxohexyl)carbamoyl)-4,7-dichloro-3-oxo-2',7'-diphenyl-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)
InChI: InChI=1S/C91H95Cl2N6O17P/c1-55(2)99(56(3)4)117(110-46-26-43-94)116-75-52-78(112-76(75)54-109-90(60-32-21-15-22-33-60,61-35-39-63(107-11)40-36-61)62-37-41-64(108-12)42-38-62)98-53-59(82(101)97-87(98)106)31-25-45-95-77(100)34-23-16-24-44-96-83(102)67-49-70(92)79-80(81(67)93)91(115-84(79)103)68-47-65(57-27-17-13-18-28-57)71(113-85(104)88(5,6)7)50-73(68)111-74-51-72(114-86(105)89(8,9)10)66(48-69(74)91)58-29-19-14-20-30-58/h13-15,17-22,25,27-33,35-42,47-51,53,55-56,75-76,78H,16,23-24,26,34,44-46,52,54H2,1-12H3,(H,95,100)(H,96,102)(H,97,101,106)/t75-,76+,78+,117?/m0/s1
Synonyms: SIMA-dT phosphoramidite, 6-isomer; 5'-Dimethoxytrityl-5-[6-((2',7'-diphenyl-4,7-dichloro-3',6'-dipivaloylfluorescein-6-yl-carboxamido)-hexanoyl)-3-aminoallyl]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
2-[5-[1-[6-[[trans-4-[[[Bis(1-methylethyl)amino](2-cyanoethyl)phosphino]oxy]cyclohexyl]amino]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1,3,3-trimethyl-3H-indolium, hexafluorophosphate(1-) (1:1)
Description: It is a type of fluorescent probe. Its highly conjugated structure, including the indolium-based chromophores, enables it to emit fluorescence upon excitation, making it useful in various applications such as imaging, detection, and analytical studies in biological and chemical environments. The specific functional groups and substituents enhance its solubility, stability, and interaction with target molecules, making it a versatile tool in fluorescence-based assays.
CAT: BRP-02352
CAS: 1032678-33-3
Molecular Formula: C47H67N5O2P.F6P
Molecular Weight: 910.01
Purity: ≥95%
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InChIKey: CXTKSIZCEDZHOE-PVMSMBLDNA-O
CanonicalSMILES: N#CCCP(OC1CCC(NC(=O)CCCCCN2C=3C=CC=CC3C(C2=CC=CC=CC4=[N+](C=5C=CC=CC5C4(C)C)C)(C)C)CC1)N(C(C)C)C(C)C.[F-][P+5]([F-])([F-])([F-])([F-])[F-]
IUPAC Name: 1-(6-(((1r,4r)-4-(((2-cyanoethyl)(diisopropylamino)phosphaneyl)oxy)cyclohexyl)amino)-6-oxohexyl)-3,3-dimethyl-2-(5-(1,3,3-trimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-3H-indol-1-ium;hexafluorophosphate
InChI: InChI=1/C47H66N5O2P.F6P/c1-35(2)52(36(3)4)55(34-20-32-48)54-38-30-28-37(29-31-38)49-45(53)27-14-11-19-33-51-42-24-18-16-22-40(42)47(7,8)44(51)26-13-10-12-25-43-46(5,6)39-21-15-17-23-41(39)50(43)9;1-7(2,3,4,5)6/h10,12-13,15-18,21-26,35-38H,11,14,19-20,27-31,33-34H2,1-9H3;/q;-1/p+1/t37-,38-,55?;
Synonyms: 3H-Indolium, 2-[5-[1-[6-[[trans-4-[[[bis(1-methylethyl)amino](2-cyanoethyl)phosphino]oxy]cyclohexyl]amino]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-1,3,3-trimethyl-, hexafluorophosphate(1-) (1:1)
Related CAS: 1032678-32-2 (free base)
Quasar 670 Amidite
Description: Quasar 670 Amidite is a fluorescent dye amidite used in the synthesis of labeled oligonucleotides. It incorporates the Quasar 670 dye, which emits in the far-red region of the spectrum, into the oligonucleotide during solid-phase synthesis. This dye is commonly used for applications in molecular biology and diagnostics, including fluorescence-based assays, real-time PCR, and other nucleic acid detection methods. The far-red fluorescence of Quasar 670 provides advantages in minimizing background interference and allows for multiplexing with other dyes.
CAT: BRP-02353
CAS: 1207163-26-5
Molecular Formula: C46H67N5O4P.F6P
Molecular Weight: 929.99
Purity: ≥95%
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InChIKey: YDZHKALIHBAHCU-UHFFFAOYSA-O
CanonicalSMILES: N#CCCOP(OCCOCCNC(=O)CCCCCN1C=2C=CC=CC2C(C1=CC=CC=CC3=[N+](C=4C=CC=CC4C3(C)C)CC)(C)C)N(C(C)C)C(C)C.[F-][P+5]([F-])([F-])([F-])([F-])[F-]
IUPAC Name: 1-(6-((2-(2-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)ethoxy)ethyl)amino)-6-oxohexyl)-2-(5-(1-ethyl-3,3-dimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-3,3-dimethyl-3H-indol-1-ium;hexafluorophosphate
InChI: InChI=1S/C46H66N5O4P.F6P/c1-10-49-40-24-18-16-22-38(40)45(6,7)42(49)26-13-11-14-27-43-46(8,9)39-23-17-19-25-41(39)50(43)31-20-12-15-28-44(52)48-30-33-53-34-35-55-56(54-32-21-29-47)51(36(2)3)37(4)5;1-7(2,3,4,5)6/h11,13-14,16-19,22-27,36-37H,10,12,15,20-21,28,30-35H2,1-9H3;/q;-1/p+1
Synonyms: 3H-Indolium, 2-[5-[1-[14-[bis(1-methylethyl)amino]-17-cyano-6-oxo-10,13,15-trioxa-7-aza-14-phosphaheptadec-1-yl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1,3-pentadienyl]-1-ethyl-3,3-dimethyl-, hexafluorophosphate(1-) (1:1); Quasar 670 CE Phosphoramidite; Quasar 670 Phosphoramidite
Related CAS: 865651-00-9 (free base) ; 865611-62-7 (iodide salt)
Quasar 670-dT Phosphoramidite
Description: Quasar 670 dyes are cyanine derivatives of Cyanine 5. Cyanine dyes are a popular oligonucleotide modification and are commonly used for imaging, flow cytometry, and genomic applications.
CAT: BRP-02354
Molecular Formula: C81H102F6N8O10P2
Molecular Weight: 1523.69
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Storage: Store at -20 °C
Solubility: Soluble in Anhydrous Acetonitrile
IUPAC Name: 2-(5-(1-(6-((6-(3-(1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylamido)hexyl)amino)-6-oxohexyl)-3,3-dimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium;hexafluorophosphate
Synonyms: 5'-Dimethoxytrityloxy-5-[(N-(6-(N1-ethyl-3,3,3',3'-tetramethylindodicarbocyanin-1'-yl)hexanoyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite, hexafluorophosphate salt
BHQ-1-dT CE Phosphoramidite
Description: BHQ-1-dT, a widely utilized reagent in the biomedicine realm, remains pertinent for nucleic acid detection and DNA sequencing. Its potential significance surfaces in disease and genetic disorder determination alongside viral load monitoring in infectious cases. From a development standpoint, BHQ-1-dT fosters therapeutic targeting of nucleic acids.
CAT: BRP-02355
Molecular Formula: C74H89N12O14P
Molecular Weight: 1401.56
Purity: ≥95%
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Storage: Store at -20 °C
InChIKey: MNVPAZMXRNVVHL-KGKIMOMESA-N
Solubility: Soluble in Anhydrous Acetonitrile/Dichloromethane 1:3 (v/v)
CanonicalSMILES: CCN(CCOC(=O)NCCCCCCNC(=O)C=CC1=CN(C(=O)NC1=O)C2CC(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N(C(C)C)C(C)C)OCCC#N)C6=CC=C(C=C6)N=NC7=C(C=C(C(=C7)C)N=NC8=C(C=C(C=C8)C)[N+](=O)[O-])OC
IUPAC Name: 2-[N-ethyl-4-[[2-methoxy-5-methyl-4-[(4-methyl-2-nitrophenyl)diazenyl]phenyl]diazenyl]anilino]ethyl N-[6-[[3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoyl]amino]hexyl]carbamate
InChI: InChI=1S/C74H89N12O14P/c1-11-83(59-30-28-58(29-31-59)79-82-64-45-53(7)63(46-66(64)95-10)81-80-62-36-22-52(6)44-65(62)86(91)92)41-43-96-73(90)77-40-18-13-12-17-39-76-69(87)37-23-54-48-84(72(89)78-71(54)88)70-47-67(100-101(98-42-19-38-75)85(50(2)3)51(4)5)68(99-70)49-97-74(55-20-15-14-16-21-55,56-24-32-60(93-8)33-25-56)57-26-34-61(94-9)35-27-57/h14-16,20-37,44-46,48,50-51,67-68,70H,11-13,17-19,39-43,47,49H2,1-10H3,(H,76,87)(H,77,90)(H,78,88,89)/b37-23+,81-80?,82-79?/t67-,68+,70+,101?/m0/s1
Synonyms: BHQ-1-dT; HCQ-12-dT Phosphoramidite; 5'-Dimethoxytrityloxy-5-[(N-4''-carboxyethyl-4''-(N-ethyl)-4'-(2-Nitro-4-toluyldiazo)-2'-methoxy-5'-methyl-azobenzene)-aminohexyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; BHQ-1-dT Amidite
BHQ-2-dT
Description: BHQ-2-dT plays a critical role in propelling PCR probes and hybridization assays to new heights of detection, this modified nucleoside serves as a beacon for identifying viral pathogens, genetic diseases, and cancer biomarkers. With its distinctive fluorescent abilities, molecular matching is taken to the next level of precision and accuracy, boosting sensitivity like never before.
CAT: BRP-02356
CAS: 1415097-34-5
Molecular Formula: C73H87N12O15P
Molecular Weight: 1403.53
Purity: ≥95%
Appearance: Blue Solid
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Storage: Store at -20 °C
InChIKey: QCQIEDGINBSSOG-GOQRVKJUSA-N
Solubility: Soluble in Anhydrous Acetonitrile/Dichloromethane 1:3 (v/v)
CanonicalSMILES: N#CCCOP(OC1CC(OC1COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C=C(C=CC(=O)NCCCCCCNC(=O)OCCN(C6=CC=C(N=NC7=CC(OC)=C(N=NC8=CC=C(C=C8)N(=O)=O)C=C7OC)C=C6)CC)C(=O)NC5=O)N(C(C)C)C(C)C
IUPAC Name: 2-[4-[[2,5-dimethoxy-4-[(4-nitrophenyl)diazenyl]phenyl]diazenyl]-N-ethylanilino]ethyl N-[6-[[(E)-3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoyl]amino]hexyl]carbamate
InChI: InChI=1S/C73H87N12O15P/c1-10-82(58-30-26-56(27-31-58)78-80-62-45-65(95-9)63(46-64(62)94-8)81-79-57-28-32-59(33-29-57)85(90)91)42-44-96-72(89)76-41-17-12-11-16-40-75-68(86)38-21-52-48-83(71(88)77-70(52)87)69-47-66(100-101(98-43-18-39-74)84(50(2)3)51(4)5)67(99-69)49-97-73(53-19-14-13-15-20-53,54-22-34-60(92-6)35-23-54)55-24-36-61(93-7)37-25-55/h13-15,19-38,45-46,48,50-51,66-67,69H,10-12,16-18,40-44,47,49H2,1-9H3,(H,75,86)(H,76,89)(H,77,87,88)/t66-,67+,69+,101?/m0/s1
Synonyms: HCQ-2-dT Phosphoramidite; BHQ-2-dT CE Phosphoramidite; 5'-Dimethoxytrityloxy-5-[(N-4''-carboxyethyl-4''-(N-ethyl)-4'-(4-Nitro-phenyldiazo)-2'-methoxy-5'-methoxy-azobenzene)-aminohexyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; BHQ-2-dT Phosphoramidite; BHQ-2-dT Amidite
Amino-Modifier C6 dT
Description: Amino-Modifier C6 dT is a pivotal aspect, serving as a prized instrument for conducting comprehensive nucleic acid investigations. This extraordinary compound has played a crucial role in augmenting the realm of pharmaceutical transport mechanisms and diagnostic apparatuses.
CAT: BRP-02357
CAS: 210534-16-0
Molecular Formula: C50H62F3N6O10P
Molecular Weight: 995.03
Purity: 95%
Appearance: Off-white Solid
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Storage: Store at 2-8 °C
InChIKey: XHGOWDJUVKONLU-HAKODNTASA-N
Solubility: Soluble in Anhydrous Acetonitrile, DMSO
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C=CC(=O)NCCCCCCNC(=O)C(F)(F)F
IUPAC Name: (E)-3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]-N-[6-[(2,2,2-trifluoroacetyl)amino]hexyl]prop-2-enamide
InChI: InChI=1S/C50H62F3N6O10P/c1-34(2)59(35(3)4)70(67-30-14-27-54)69-42-31-45(58-32-36(46(61)57-48(58)63)17-26-44(60)55-28-12-7-8-13-29-56-47(62)50(51,52)53)68-43(42)33-66-49(37-15-10-9-11-16-37,38-18-22-40(64-5)23-19-38)39-20-24-41(65-6)25-21-39/h9-11,15-26,32,34-35,42-43,45H,7-8,12-14,28-31,33H2,1-6H3,(H,55,60)(H,56,62)(H,57,61,63)/b26-17+/t42-,43+,45+,70?/m0/s1
Synonyms: Amino-modifier C6 dT CE Phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[(1E)-3-oxo-3-[[6-[(2,2,2-trifluoroacetyl)amino]hexyl]amino]-1-propen-1-yl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-5-[(1E)-3-oxo-3-({6-[(trifluoroacetyl)amino]hexyl}amino)-1-propen-1-yl]uridine; Amino-modifier C6 dT Phosphoramidite; Amino-Modifier C6 dT CEP
Biotin-dT CE-Phosphoramidite
Description: Biotin-dT CE-Phosphoramidite is a prestigious compound, engaged in the critical tasks of labeling and detecting DNA or RNA sequences. With the amalgamation of biotin, this meticulously modified nucleotide engenders a realm of convenience for meticulous purification processes, unrivaled amplification endeavors and captivating visualization techniques.
CAT: BRP-02358
CAS: 198080-40-9
Molecular Formula: C69H89N8O12PS
Molecular Weight: 1285.55
Purity: 95%
Appearance: White, off-white to light yellow powder
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Storage: Store at -20 °C
InChIKey: FHABSPMZQJOPSS-GGVSAJPNSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C=CC(=O)NCCCCCCNC(=O)CCCCC6C7C(CS6)N(C(=O)N7)C(=O)C8=CC=C(C=C8)C(C)(C)C
IUPAC Name: 5-[(3aR,6S,6aS)-3-(4-tert-butylbenzoyl)-2-oxo-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]-N-[6-[3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-enoylamino]hexyl]pentanamide
InChI: InChI=1S/C69H89N8O12PS/c1-46(2)77(47(3)4)90(87-41-19-38-70)89-57-42-62(88-58(57)44-86-69(51-20-13-12-14-21-51,52-29-33-54(84-8)34-30-52)53-31-35-55(85-9)36-32-53)75-43-49(64(80)74-66(75)82)26-37-61(79)72-40-18-11-10-17-39-71-60(78)23-16-15-22-59-63-56(45-91-59)76(67(83)73-63)65(81)48-24-27-50(28-25-48)68(5,6)7/h12-14,20-21,24-37,43,46-47,56-59,62-63H,10-11,15-19,22-23,39-42,44-45H2,1-9H3,(H,71,78)(H,72,79)(H,73,83)(H,74,80,82)/t56-,57-,58+,59-,62+,63-,90?/m0/s1
Synonyms: 5'-Dimethoxytrityloxy-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Biotin-dT Amidite; Biotin-dT Phosphoramidite; (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-(3-((6-(5-((3aS,4S,6aR)-1-(4-(tert-butyl)benzoyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexyl)amino)-3-oxoprop-1-en-1-yl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMTr-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-dT-3'-CE-phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-5-[N-((4-t-butylbenzoyl)-biotinyl)-aminohexyl)-3-acrylimido]-2'-deoxythymidine-3'-O-[(2-cyanoethyl)-N,N-diisopropyl]-phosphoramidite; Biotin-dT
FAM-xtra Phosphoramidite
Description: Oligonucleotides made from FAM-xtra phosphamide have considerable advantages over 6-FAM-labeled nucleotides.
CAT: BRP-02359
CAS: 2304636-67-5
Molecular Formula: C46H56F2N3O10P
Molecular Weight: 879.94
Purity: ≥95%
Appearance: White Solid
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InChIKey: LOTXQVJIDMUGJL-UHFFFAOYSA-N
CanonicalSMILES: N#CCCOP(OCCCCCCNC(=O)C1=CC=C2C(=O)OC3(C4=CC(F)=C(OC(=O)C(C)(C)C)C=C4OC5=CC(OC(=O)C(C)(C)C)=C(F)C=C53)C2=C1)N(C(C)C)C(C)C
IUPAC Name: 6-((6-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)hexyl)carbamoyl)-2',7'-difluoro-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)
InChI: InChI=1S/C46H56F2N3O10P/c1-27(2)51(28(3)4)62(57-21-15-18-49)56-20-14-12-11-13-19-50-40(52)29-16-17-30-31(22-29)46(61-41(30)53)32-23-34(47)38(59-42(54)44(5,6)7)25-36(32)58-37-26-39(35(48)24-33(37)46)60-43(55)45(8,9)10/h16-17,22-28H,11-15,19-21H2,1-10H3,(H,50,52)
Fluorescein II CEP
Description: Fluorescein II CEP is a derivative of fluorescein, which is used in many fluorescent tracers. It can be attached to certain bioactive molecules, thus allowing biologists to target fluorophores to specific proteins or structures within cells.
CAT: BRP-02360
CAS: 1027512-13-5
Molecular Formula: C67H76N3O14P
Molecular Weight: 1178.33
Purity: ≥95%
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Storage: Store at 2-8 °C
Boiling Point: 1063.4±65.0 °C (Predicted)
InChIKey: ZQNXVFAFTICSEX-UHFFFAOYSA-N
CanonicalSMILES: N#CCCOP(OC(COCCCNC(=O)C1=CC=C2C(=O)OC3(C4=CC=C(OC(=O)C(C)(C)C)C=C4OC5=CC(OC(=O)C(C)(C)C)=CC=C53)C2=C1)COC(C=6C=CC=CC6)(C7=CC=C(OC)C=C7)C8=CC=C(OC)C=C8)N(C(C)C)C(C)C
IUPAC Name: 6-((3-(3-(bis(4-methoxyphenyl)(phenyl)methoxy)-2-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)propoxy)propyl)carbamoyl)-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)
InChI: InChI=1S/C67H76N3O14P/c1-43(2)70(44(3)4)85(79-37-16-34-68)84-53(42-78-66(46-18-14-13-15-19-46,47-21-25-49(75-11)26-22-47)48-23-27-50(76-12)28-24-48)41-77-36-17-35-69-60(71)45-20-31-54-57(38-45)67(83-61(54)72)55-32-29-51(80-62(73)64(5,6)7)39-58(55)82-59-40-52(30-33-56(59)67)81-63(74)65(8,9)10/h13-15,18-33,38-40,43-44,53H,16-17,35-37,41-42H2,1-12H3,(H,69,71)
Synonyms: 6-Fluorescein CE Phosphoramidite; Propanoic acid, 2,2-dimethyl-, 1,1'-[6-[8-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-(2-cyanoethoxy)-12-methyl-11-(1-methylethyl)-1-oxo-6,9-dioxa-2,11-diaza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] ester; 1,1'-[6-[8-[[Bis(4-methoxyphenyl)phenylmethoxy]methyl]-10-(2-cyanoethoxy)-12-methyl-11-(1-methylethyl)-1-oxo-6,9-dioxa-2,11-diaza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl] bis(2,2-dimethylpropanoate)
