What are phosphoramidites used for?

Phosphoramidites are activated monomers used in solid-phase DNA and RNA oligonucleotide synthesis.

What is the difference between DNA and RNA phosphoramidites?

RNA phosphoramidites include additional 2′-hydroxyl protecting groups, making them more sensitive to moisture and handling conditions.

Why is moisture control important for phosphoramidites?

Moisture can cause premature hydrolysis of phosphoramidites, reducing coupling efficiency and synthesis yield.

Can phosphoramidites be used for long oligonucleotide synthesis?

Yes, high-quality phosphoramidites are essential for achieving good yields in long and complex oligonucleotide sequences.

Are modified phosphoramidites available for custom oligos?

Modified and specialty phosphoramidites are commonly used to introduce functional groups or labels into oligonucleotides.

Phosphoramidites - RNA / BOC Sciences

Fmoc-PNA-C(Boc)-OH

Description: Fmoc-PNA-C(Boc)-OH is a synthetic peptide nucleic acid (PNA) modified with Fmoc and Boc protecting groups, designed for controlled synthesis and specific binding to complementary DNA or RNA sequences. It serves as a valuable tool in molecular biology, offering high specificity and stability in nucleic acid interactions and applications ranging from basic research to diagnostics and therapeutic development.

CAT: BRP-02054

CAS: 172405-61-7

Molecular Formula: C30H33N5O8

Molecular Weight: 591.61

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: -20°C for long term storage

Density: 1.35±0.1 g/cm3

InChIKey: XTXTTZCNVKRDDX-UHFFFAOYSA-N

CanonicalSMILES: CC(C)(C)OC(=O)NC1=NC(=O)N(C=C1)CC(=O)N(CCNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)CC(=O)O

IUPAC Name: 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl-[2-[4-[(2-methylpropan-2-yl)oxycarbonylamino]-2-oxopyrimidin-1-yl]acetyl]amino]acetic acid

InChI: InChI=1S/C30H33N5O8/c1-30(2,3)43-29(41)33-24-12-14-35(27(39)32-24)16-25(36)34(17-26(37)38)15-13-31-28(40)42-18-23-21-10-6-4-8-19(21)20-9-5-7-11-22(20)23/h4-12,14,23H,13,15-18H2,1-3H3,(H,31,40)(H,37,38)(H,32,33,39,41)

Synonyms: Glycine, N-[[4-[[(1,1-dimethylethoxy)carbonyl]amino]-2-oxo-1(2H)-pyrimidinyl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]-; N-[2-[4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-oxo-1(2H)-pyrimidinyl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(4-((tert-butoxycarbonyl)amino)-2-oxopyrimidin-1(2H)-yl)acetyl)glycine

Fmoc-PNA-G(Boc)-OH

Description: Fmoc-PNA-G(Boc)-OH is a synthetic peptide nucleic acid (PNA) modified with Fmoc and Boc protecting groups, designed for precise synthesis and targeted binding to complementary DNA or RNA sequences. It serves as a versatile tool in molecular biology, offering robustness, specificity, and applicability across various research and diagnostic fields.

CAT: BRP-02055

CAS: 1052677-90-3

Molecular Formula: C31H33N7O8

Molecular Weight: 631.64

Purity: ≥95%

Appearance: White to Off-white Powder

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Density: 1.46±0.1 g/cm3

InChIKey: JVIAXIMEDXKTSN-UHFFFAOYSA-N

CanonicalSMILES: CC(C)(C)OC(=O)NC1=NC2=C(C(=O)N1)N=CN2CC(=O)N(CCNC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)CC(=O)O

IUPAC Name: 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]-6-oxo-1H-purin-9-yl]acetyl]amino]acetic acid

InChI: InChI=1S/C31H33N7O8/c1-31(2,3)46-30(44)36-28-34-26-25(27(42)35-28)33-17-38(26)14-23(39)37(15-24(40)41)13-12-32-29(43)45-16-22-20-10-6-4-8-18(20)19-9-5-7-11-21(19)22/h4-11,17,22H,12-16H2,1-3H3,(H,32,43)(H,40,41)(H2,34,35,36,42,44)

Synonyms: N-[2-[2-[[(1,1-Dimethylethoxy)carbonyl]amino]-1,6-dihydro-6-oxo-9H-purin-9-yl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(2-((tert-butoxycarbonyl)amino)-6-oxo-1,6-dihydro-9H-purin-9-yl)acetyl)glycine; 2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(2-((tert-butoxycarbonyl)amino)-6-oxo-1H-purin-9(6H)-yl)acetamido)acetic acid

Boc-PNA-U-OH

Description: Boc-PNA-U-OH is a synthetic peptide nucleic acid (PNA) modified with the Boc protecting group, designed for controlled synthesis and targeted binding to complementary DNA or RNA sequences. It serves as a versatile tool in molecular biology research, offering high specificity and utility across various applications in gene regulation, diagnostics, and nucleic acid research.

CAT: BRP-02056

CAS: 149500-74-3

Molecular Formula: C15H22N4O7

Molecular Weight: 370.36

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: -20°C for long term storage

Density: 1.335±0.06 g/cm3

Melting Point: 164-170 °C

InChIKey: ZPRZPMGSCWEHKC-UHFFFAOYSA-N

CanonicalSMILES: O=C(OC(C)(C)C)NCCN(C(=O)CN1C=CC(=O)NC1=O)CC(=O)O

IUPAC Name: N-(2-((tert-butoxycarbonyl)amino)ethyl)-N-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetyl)glycine

InChI: InChI=1S/C15H22N4O7/c1-15(2,3)26-14(25)16-5-7-18(9-12(22)23)11(21)8-19-6-4-10(20)17-13(19)24/h4,6H,5,7-9H2,1-3H3,(H,16,25)(H,22,23)(H,17,20,24)

Synonyms: Glycine, N-[(3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; N-[2-(3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidinyl)acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]glycine

Boc-PNA-M(Z)-OH

Description: Boc-PNA-M(Z)-OH is a PNA monomer with a Boc protecting group on the terminal amine and a Cbz protecting group on the modified base. It is used in the synthesis of peptide nucleic acids (PNAs). The Boc group facilitates solid-phase synthesis by protecting the amine group, while the Z group protects the base during chemical reactions.

CAT: BRP-02057

Molecular Formula: C24H30N4O7

Molecular Weight: 486.53

Purity: ≥95%

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InChIKey: CXZDUTOZNUXMQC-UHFFFAOYSA-N

CanonicalSMILES: O=C(O)CN(C(CC1=CC=C(NC(OCC2=CC=CC=C2)=O)N=C1)=O)CCNC(OC(C)(C)C)=O

IUPAC Name: N-(2-(6-(((benzyloxy)carbonyl)amino)pyridin-3-yl)acetyl)-N-(2-((tert-butoxycarbonyl)amino)ethyl)glycine

InChI: InChI=1S/C24H30N4O7/c1-24(2,3)35-22(32)25-11-12-28(15-21(30)31)20(29)13-18-9-10-19(26-14-18)27-23(33)34-16-17-7-5-4-6-8-17/h4-10,14H,11-13,15-16H2,1-3H3,(H,25,32)(H,30,31)(H,26,27,33)

Fmoc-PNA-M(Bhoc)-OH

Description: Fmoc-PNA-M(Bhoc)-OH is a PNA monomer with an Fmoc protecting group on the terminal amine, and a Bhoc protecting group on the modified base. It is used in the synthesis of peptide nucleic acids (PNAs) which are synthetic analogs of DNA and RNA. The Fmoc group allows for solid-phase synthesis, while the Bhoc group protects the base during chemical reactions.

CAT: BRP-02058

Molecular Formula: C40H36N4O7

Molecular Weight: 684.75

Purity: ≥95%

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InChIKey: ZVLCJMSLDDKFKX-UHFFFAOYSA-N

CanonicalSMILES: O=C(O)CN(C(CC1=CC=C(NC(OC(C2=CC=CC=C2)C3=CC=CC=C3)=O)N=C1)=O)CCNC(OCC4C5=C(C=CC=C5)C6=C4C=CC=C6)=O

IUPAC Name: N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(6-(((benzhydryloxy)carbonyl)amino)pyridin-3-yl)acetyl)glycine

InChI: InChI=1S/C40H36N4O7/c45-36(23-27-19-20-35(42-24-27)43-40(49)51-38(28-11-3-1-4-12-28)29-13-5-2-6-14-29)44(25-37(46)47)22-21-41-39(48)50-26-34-32-17-9-7-15-30(32)31-16-8-10-18-33(31)34/h1-20,24,34,38H,21-23,25-26H2,(H,41,48)(H,46,47)(H,42,43,49)

Fmoc-PNA-M(Boc)-OH

Description: Fmoc-PNA-M(Boc)-OH is a PNA monomer with an Fmoc protecting group on the terminal amine and a Boc protecting group on the modified base. It is used in the synthesis of peptide nucleic acids (PNAs). The Fmoc group facilitates solid-phase synthesis by protecting the amine group, while the Boc group protects the base during chemical reactions.

CAT: BRP-02059

CAS: 1417611-27-8

Molecular Formula: C31H34N4O7

Molecular Weight: 574.62

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: -20°C for long term storage

Density: 1.308±0.06 g/cm3

Boiling Point: 781.3±60.0 °C at 760 mmHg

InChIKey: KKGJHNNYUDROSA-UHFFFAOYSA-N

CanonicalSMILES: CC(C)(C)OC(=O)NC1=NC=C(C=C1)CC(=O)N(CCNC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)CC(=O)O

IUPAC Name: 2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl-[2-[6-[(2-methylpropan-2-yl)oxycarbonylamino]pyridin-3-yl]acetyl]amino]acetic acid

InChI: InChI=1S/C31H34N4O7/c1-31(2,3)42-30(40)34-26-13-12-20(17-33-26)16-27(36)35(18-28(37)38)15-14-32-29(39)41-19-25-23-10-6-4-8-21(23)22-9-5-7-11-24(22)25/h4-13,17,25H,14-16,18-19H2,1-3H3,(H,32,39)(H,37,38)(H,33,34,40)

Synonyms: 2-(N-(2-(Fmoc)ethyl)-2-(6-(tert-butoxycarbonylamino)pyridin-3-yl)acetamido)acetic acid; N-[2-[6-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-pyridinyl]acetyl]-N-[2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]ethyl]glycine; N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(6-((tert-butoxycarbonyl)amino)pyridin-3-yl)acetyl)glycine

Fmoc-PNA-J(Bhoc)-OH

Description: Fmoc-PNA-J(Bhoc)-OH is a PNA monomer used in the synthesis of peptide nucleic acids (PNAs). It features an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group on the terminal amine and a Bhoc (benzyloxycarbonyl) protecting group on the modified base J. These protecting groups facilitate solid-phase synthesis, ensuring the integrity of the monomer and preventing unwanted side reactions during the assembly of PNA sequences.

CAT: BRP-02060

Molecular Formula: C39H35N5O8

Molecular Weight: 701.74

Purity: ≥95%

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InChIKey: AXTIXKVVQRPTAF-UHFFFAOYSA-N

CanonicalSMILES: O=C(O)CN(CCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(CC4=CN=C(NC(OC(C5=CC=CC=C5)C6=CC=CC=C6)=O)NC4=O)=O

IUPAC Name: N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(2-(((benzhydryloxy)carbonyl)amino)-6-oxo-1,6-dihydropyrimidin-5-yl)acetyl)glycine

InChI: InChI=1S/C39H35N5O8/c45-33(21-27-22-41-37(42-36(27)48)43-39(50)52-35(25-11-3-1-4-12-25)26-13-5-2-6-14-26)44(23-34(46)47)20-19-40-38(49)51-24-32-30-17-9-7-15-28(30)29-16-8-10-18-31(29)32/h1-18,22,32,35H,19-21,23-24H2,(H,40,49)(H,46,47)(H2,41,42,43,48,50)

Fmoc-PNA-D(tetraBhoc)-OH

Description: Fmoc-PNA-D(tetraBhoc)-OH is a peptide nucleic acid (PNA) monomer used in the synthesis of PNAs. It features an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group on the terminal amine and tetraBhoc (tetra benzyloxycarbonyl) protecting groups on the modified base D. These protecting groups are essential for solid-phase synthesis, ensuring that the monomer remains stable and reactive only at the desired stages of the assembly process. This monomer is particularly useful for creating PNAs with specific binding properties and enhanced stability.

CAT: BRP-02061

Molecular Formula: C82H66N8O13

Molecular Weight: 1371.47

Purity: ≥95%

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InChIKey: JQBRHDKMTRBGAE-UHFFFAOYSA-N

CanonicalSMILES: O=C(O)CN(CCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)C(CN4C=NC5=C4N=C(N(C(OC(C6=CC=CC=C6)C7=CC=CC=C7)=O)C(OC(C8=CC=CC=C8)C9=CC=CC=C9)=O)N=C5N(C(OC(C%10=CC=CC=C%10)C%11=CC=CC=C%11)=O)C(OC(C%12=CC=CC=C%12)C%13=CC=CC=C%13)=O)=O

IUPAC Name: N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(2,6-bis(bis((benzhydryloxy)carbonyl)amino)-9H-purin-9-yl)acetyl)glycine

InChI: InChI=1S/C82H66N8O13/c91-68(87(52-69(92)93)50-49-83-78(94)99-53-67-65-47-27-25-45-63(65)64-46-26-28-48-66(64)67)51-88-54-84-70-75(88)85-77(90(81(97)102-73(59-37-17-5-18-38-59)60-39-19-6-20-40-60)82(98)103-74(61-41-21-7-22-42-61)62-43-23-8-24-44-62)86-76(70)89(79(95)100-71(55-29-9-1-10-30-55)56-31-11-2-12-32-56)80(96)101-72(57-33-13-3-14-34-57)58-35-15-4-16-36-58/h1-48,54,67,71-74H,49-53H2,(H,83,94)(H,92,93)

Fmoc-PNA-D(tetraBoc)-OH

Description: Fmoc-PNA-D(tetraBoc)-OH is a peptide nucleic acid (PNA) monomer used in the synthesis of PNA oligomers. It features an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group on the terminal amine and tetraBoc (tetra tert-butoxycarbonyl) protecting groups on the modified base D. These protecting groups help maintain the integrity of the monomer during the solid-phase synthesis process, allowing for precise and controlled assembly of PNA sequences. This monomer is valuable for creating PNAs with tailored binding characteristics and increased stability for various biochemical applications.

CAT: BRP-02062

CAS: 2101661-88-3

Molecular Formula: C46H58N8O13

Molecular Weight: 931.00

Purity: ≥95%

Appearance: White to Light Beige Solid

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Storage: Store at -20°C under inert atmosphere

Density: 1.30±0.1 g/cm3

Melting Point: 135-140°C

Boiling Point: 402.2±55.0°C (Predicted)

InChIKey: FNWBHNGZUCVYGL-UHFFFAOYSA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly)

CanonicalSMILES: CC(C)(C)OC(=O)N(C1=NC(=NC2=C1N=CN2CC(=O)N(CCNC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)CC(=O)O)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

IUPAC Name: 2-[[2-[2,6-bis[bis[(2-methylpropan-2-yl)oxycarbonyl]amino]purin-9-yl]acetyl]-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]amino]acetic acid

InChI: InChI=1S/C46H58N8O13/c1-43(2,3)64-39(59)53(40(60)65-44(4,5)6)36-34-35(49-37(50-36)54(41(61)66-45(7,8)9)42(62)67-46(10,11)12)52(26-48-34)23-32(55)51(24-33(56)57)22-21-47-38(58)63-25-31-29-19-15-13-17-27(29)28-18-14-16-20-30(28)31/h13-20,26,31H,21-25H2,1-12H3,(H,47,58)(H,56,57)

Synonyms: 2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(2,6-bis(bis(tert-butoxycarbonyl)amino)-9H-purin-9-yl)acetamido)acetic acid; N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(2,6-bis(bis(tert-butoxycarbonyl)amino)-9H-purin-9-yl)acetyl)glycine; 2-{2-[2,6-bis({bis[(tert-butoxy)carbonyl]amino})-9H-purin-9-yl]-N-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]acetamido}acetic acid

Boc-PNA-D(tetraZ)-OH

Description: Boc-PNA-D(tetraZ)-OH is a peptide nucleic acid (PNA) monomer used in the synthesis of PNA oligomers. It features a Boc (tert-butoxycarbonyl) protecting group on the terminal amine and tetraZ (tetra benzyloxycarbonyl) protecting groups on the modified base D. These protecting groups are utilized to protect reactive sites during the solid-phase synthesis, ensuring accurate assembly of PNA sequences. This monomer is important for constructing PNAs with specific binding properties and enhanced stability for various biochemical and biomedical applications.

CAT: BRP-02063

Molecular Formula: C48H48N8O13

Molecular Weight: 944.96

Purity: ≥95%

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InChIKey: XREWKMOLHCLRJZ-UHFFFAOYSA-N

CanonicalSMILES: O=C(O)CN(CCNC(OC(C)(C)C)=O)C(CN1C=NC2=C1N=C(N(C(OCC3=CC=CC=C3)=O)C(OCC4=CC=CC=C4)=O)N=C2N(C(OCC5=CC=CC=C5)=O)C(OCC6=CC=CC=C6)=O)=O

IUPAC Name: N-(2-(2,6-bis(bis((benzyloxy)carbonyl)amino)-9H-purin-9-yl)acetyl)-N-(2-((tert-butoxycarbonyl)amino)ethyl)glycine

InChI: InChI=1S/C48H48N8O13/c1-48(2,3)69-43(60)49-24-25-53(27-38(58)59)37(57)26-54-32-50-39-40(54)51-42(56(46(63)67-30-35-20-12-6-13-21-35)47(64)68-31-36-22-14-7-15-23-36)52-41(39)55(44(61)65-28-33-16-8-4-9-17-33)45(62)66-29-34-18-10-5-11-19-34/h4-23,32H,24-31H2,1-3H3,(H,49,60)(H,58,59)

ENA-T-Phosphoramidite

Description: ENA-T-Phosphoramidite is a specialized reagent used in oligonucleotide synthesis. This phosphoramidite derivative allows for the introduction of modified nucleotide sequences into synthetic oligonucleotides, facilitating various research and biotechnological applications.

CAT: BRP-02064

CAS: 287737-40-0

Molecular Formula: C42H51N4O9P

Molecular Weight: 786.86

Purity: ≥95%

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InChIKey: BCXPUDBJUMTTSQ-RWDMRMDHSA-N

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C3C(C(O2)(CCO3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N

IUPAC Name: 3-[[(1R,5R,7R,8S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C42H51N4O9P/c1-28(2)46(29(3)4)56(53-24-11-23-43)55-37-36-39(45-26-30(5)38(47)44-40(45)48)54-41(37,22-25-51-36)27-52-42(31-12-9-8-10-13-31,32-14-18-34(49-6)19-15-32)33-16-20-35(50-7)21-17-33/h8-10,12-21,26,28-29,36-37,39H,11,22,24-25,27H2,1-7H3,(H,44,47,48)/t36-,37+,39-,41-,56?/m1/s1

Synonyms: ENA-T-CE-Phosphoramidite; 2,4(1H,3H)-Pyrimidinedione, 1-[2,6-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5-deoxy-α-L-lyxo-hexofuranosyl]-5-methyl-; 1-[2,6-Anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5-deoxy-α-L-lyxo-hexofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; ENA-5-Me-U-Phosphoramidite

5'-O-DMT-2'-O-TBDMS-5-Methy-L-Uridine 3'-CE phosphoramidite

Description: 5'-O-DMT-2'-O-TBDMS-5-Methyl-L-Uridine 3'-CE phosphoramidite is a specialized phosphoramidite used in the synthesis of oligonucleotides. It contains a dimethoxytrityl (DMT) group at the 5'-hydroxyl position, a tert-butyldimethylsilyl (TBDMS) group at the 2'-hydroxyl position, and a cyanoethyl (CE) group attached to the phosphoramidite. This reagent incorporates the 5-methyl modification on the uridine base, specifically in the L-configuration, into oligonucleotides, which is important for enhancing the stability and binding properties of the synthesized strands, making it useful in various genetic and therapeutic applications.

CAT: BRP-02151

Molecular Formula: C46H63N4O9PSi

Molecular Weight: 875.09

Purity: ≥95%

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Storage: Store at -20 °C

InChIKey: KYRSLFQMFXXGLW-PKLCMXGVSA-N

CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OP(N(C(C)C)C(C)C)OCCC#N)O[Si](C)(C)C(C)(C)C

IUPAC Name: 3-[[(2S,3S,4S,5S)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C46H63N4O9PSi/c1-31(2)50(32(3)4)60(56-28-16-27-47)58-40-39(57-43(41(40)59-61(11,12)45(6,7)8)49-29-33(5)42(51)48-44(49)52)30-55-46(34-17-14-13-15-18-34,35-19-23-37(53-9)24-20-35)36-21-25-38(54-10)26-22-36/h13-15,17-26,29,31-32,39-41,43H,16,28,30H2,1-12H3,(H,48,51,52)/t39-,40-,41-,43-,60?/m0/s1

Synonyms: L-Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5-Methyl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-L-uridine-3'-cyanoethyl phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]-5-methyl-L-uridine; DMT-2'-O-TBDMS-5-Me-L-rU Phosphoramidite; 5'-O-DMT-2'-O-TBDMS-L-rT Phosphoramidite; 5'-O-DMT-2'-O-TBDMS-L-MeU 3'-CE-Phosphoramidite; 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-L-5-methyluridine 3'-CE phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-β-L-T-3'-CE-Phosphoramidite

5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-L-cytidine 3'-CE phosphoramidite

Description: 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-L-cytidine 3'-CE phosphoramidite is a modified phosphoramidite designed for efficient and controlled synthesis of RNA and DNA oligonucleotides. The protective groups and modifications, such as 5'-O-DMTr, N4-acetyl, and 2'-fluoro-2'-deoxy, enhance the stability of the resulting nucleic acids and facilitate their incorporation into nucleic acid chains during solid-phase synthesis. This compound is crucial in the production of antisense oligonucleotides, siRNA, probes, and primers, providing enhanced resistance to enzymatic degradation and improved performance in various applications.

CAT: BRP-02152

CAS: 856888-81-8

Molecular Formula: C41H49FN5O8P

Molecular Weight: 789.83

Purity: ≥95%

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InChIKey: CNFKJHKDSRXNFL-NYKPPYOCSA-N

CanonicalSMILES: N#CCCOP(OC1C(F)C(OC1COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C=CC(=NC5=O)NC(=O)C)N(C(C)C)C(C)C

IUPAC Name: N-[1-[(2S,3S,4S,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-fluorooxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide

InChI: InChI=1S/C41H49FN5O8P/c1-27(2)47(28(3)4)56(53-25-11-23-43)55-38-35(54-39(37(38)42)46-24-22-36(44-29(5)48)45-40(46)49)26-52-41(30-12-9-8-10-13-30,31-14-18-33(50-6)19-15-31)32-16-20-34(51-7)21-17-32/h8-10,12-22,24,27-28,35,37-39H,11,25-26H2,1-7H3,(H,44,45,48,49)/t35-,37-,38-,39-,56?/m0/s1

Synonyms: N-[1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-L-ribofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]acetamide; (2S,3S,4S,5S)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluoro-L-cytidine 3'-CE phosphoramidite; 2'-F-Ac-L-dC CE phosphoramide; DMT-2'-F-L-dC(Ac)-CE Phosphoramidite; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxy-L-cytidine-3'-CE-Phosphoramidite; 2'-Fluoro-2'-deoxy-L-Cytidine (n-ac) CED Phosphoramidite; 5'-O-DMT-2'-F-L-dC(Ac) 3'-CE phosphoramidite

5'-O-DMT-N4-Benzoyl-2'-deoxy-2'-fluoro-cytidine phosphoramidite (BRP-02161)

Description: A novel nucleoside phosphoramidite with anticancer and antiviral properties.

CAT: BRP-02161

CAS: 161442-19-9

Molecular Formula: C46H51FN5O8P

Molecular Weight: 851.90

Purity: ≥98% by HPLC

Appearance: White to light yellow solid

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InChIKey: CKKJPMGSTGVCJJ-GNUWXFRUSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1F)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-fluorooxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C46H51FN5O8P/c1-31(2)52(32(3)4)61(58-29-13-27-48)60-42-39(59-44(41(42)47)51-28-26-40(50-45(51)54)49-43(53)33-14-9-7-10-15-33)30-57-46(34-16-11-8-12-17-34,35-18-22-37(55-5)23-19-35)36-20-24-38(56-6)25-21-36/h7-12,14-26,28,31-32,39,41-42,44H,13,29-30H2,1-6H3,(H,49,50,53,54)/t39-,41-,42-,44-,61?/m1/s1

Synonyms: 2'-Fluoro-N4-benzoyl-5'-O-DMT-2'-deoxycytidine-3'-ce-phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 2'-F-Bz-dC Phosphoramidite; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluorocytidine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite (BRP-02162)

Description: N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is an indispensable biomolecule, finding profound applications within the intricate synthesis of bespoke nucleotides, thus aiding in genetic investigations.

CAT: BRP-02162

CAS: 118380-84-0

Molecular Formula: C52H66N5O9PSi

Molecular Weight: 964.19

Appearance: White to off-white solid

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InChIKey: VWNXEDLLHIFAOL-YOVDOAOFSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C52H66N5O9PSi/c1-36(2)57(37(3)4)67(63-34-18-32-53)65-46-44(35-62-52(39-21-16-13-17-22-39,40-23-27-42(60-8)28-24-40)41-25-29-43(61-9)30-26-41)64-49(47(46)66-68(10,11)51(5,6)7)56-33-31-45(55-50(56)59)54-48(58)38-19-14-12-15-20-38/h12-17,19-31,33,36-37,44,46-47,49H,18,34-35H2,1-11H3,(H,54,55,58,59)/t44-,46-,47-,49-,67?/m1/s1

Synonyms: Bz-rC Phosphoramidite; N-Bz-2'-O-TBDMS-5'-DMT-cytidine 3'-CE phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-tert-butyldimethylsilyl)cytidine 3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite]; 5'-DMT-2'-TBDMS-N4-Bz-rC phosphoramidite; 5'-O-DMT-2'-O-TBDMS-rC (Bz) phosphoramidite; 5'-O-DMT-2'-O-TBDMS-rC(Bz) 3'-CE phosphoramidite

2'-O-Methyl-rG(N-Ac) phosphoramidite (BRP-02166)

Description: 2'-O-Methyl-rG(N-Ac) phosphoramidite is an anticancer agent with antiviral and antiparasitic activities. 2'-O-Methyl-rG(N-Ac) phosphoramidite is a modified guanosine phosphoramidite used in oligonucleotide synthesis. It features a 2'-O-methyl group, which enhances the stability of the oligonucleotide by increasing resistance to nucleases and improving binding affinity. The N-Ac (N-acetyl) group protects the amino group of the guanine base during synthesis. This reagent is particularly useful for synthesizing RNA molecules with increased stability and improved hybridization properties, making it valuable for applications in molecular biology, diagnostics, and therapeutic development.

CAT: BRP-02166

CAS: 909033-40-5

Molecular Formula: C43H52N7O9P

Molecular Weight: 841.89

Purity: ≥98%

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InChIKey: FBABQKPBRXEHBT-USUFPPIWSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1OC)N2C=NC3=C2N=C(NC3=O)NC(=O)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]acetamide

InChI: InChI=1S/C43H52N7O9P/c1-27(2)50(28(3)4)60(57-24-12-23-44)59-37-35(58-41(38(37)55-8)49-26-45-36-39(49)47-42(46-29(5)51)48-40(36)52)25-56-43(30-13-10-9-11-14-30,31-15-19-33(53-6)20-16-31)32-17-21-34(54-7)22-18-32/h9-11,13-22,26-28,35,37-38,41H,12,24-25H2,1-8H3,(H2,46,47,48,51,52)/t35-,37-,38-,41-,60?/m1/s1

Synonyms: Ac-2'-OMe-rG Phosphoramidite; N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; 5'-O-DMT-2'-O-Me-rG(Ac)-3'-CE phosphoramidite; 5'-O-DMT-2'-O-Me-rG(N-Ac)-3'-CED; 5'-DMT-2'-OMe-rG(N-Ac) Phosphoramidite; Guanosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE-phosphoramidite (BRP-02167)

Description: 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE-phosphoramidite is a novel nucleotide monophosphate with antiviral and anticancer properties.

CAT: BRP-02167

CAS: 1190089-70-3

Molecular Formula: C39H46FN4O8P

Molecular Weight: 748.78

Purity: ≥95%

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InChIKey: HQHQPAYRJJMYQX-CPBIVIIKSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1F)N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: 3-[[(2R,3R,4S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-fluorooxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C39H46FN4O8P/c1-26(2)44(27(3)4)53(50-24-10-22-41)52-36-33(51-37(35(36)40)43-23-21-34(45)42-38(43)46)25-49-39(28-11-8-7-9-12-28,29-13-17-31(47-5)18-14-29)30-15-19-32(48-6)20-16-30/h7-9,11-21,23,26-27,33,35-37H,10,24-25H2,1-6H3,(H,42,45,46)/t33-,35+,36-,37-,53?/m1/s1

Synonyms: 2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-b-D-arabinouridine-3'-CEN-phosphoramidite; 5'-O-DMT-2'-F-2'-arabinofuranosyl-deoxyuridine 3'-CE phosphoramidite; 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-α-D-arabinofuranosyl]-; 2'-ara-2'-F-2'-dU Phosphoramidite; 2'-F-U-ANA-CE Phosphoramidite

5'-O-DMT-3'-O-tert-Butyldimethylsilyl-uridine-2'-CE phosphoramidite (BRP-02169)

Description: 5'-O-DMT-3'-O-tert-Butyldimethylsilyl-uridine-2'-CE phosphoramidite is a phosphoramidite reagent used in the synthesis of oligonucleotides. It features a dimethoxytrityl (DMT) protecting group at the 5'-hydroxyl position, a tert-butyldimethylsilyl (TBDMS) protecting group at the 3'-hydroxyl position, and a cyanoethyl (CE) protecting group on the phosphoramidite at the 2' position. These protective groups ensure efficient incorporation of uridine into oligonucleotides while enhancing the stability and accuracy of synthesis. This reagent is important for creating modified oligonucleotides for research and therapeutic applications.

CAT: BRP-02169

CAS: 129451-77-0

Molecular Formula: C45H61N4O9PSi

Molecular Weight: 861.05

Purity: ≥97% by HPLC

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InChIKey: UZVSHRLVIXPYEZ-ZMHKPELYSA-N

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O[Si](C)(C)C(C)(C)C

IUPAC Name: 3-[[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-2-(2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile

InChI: InChI=1S/C45H61N4O9PSi/c1-31(2)49(32(3)4)59(55-29-15-27-46)57-41-40(58-60(10,11)44(5,6)7)38(56-42(41)48-28-26-39(50)47-43(48)51)30-54-45(33-16-13-12-14-17-33,34-18-22-36(52-8)23-19-34)35-20-24-37(53-9)25-21-35/h12-14,16-26,28,31-32,38,40-42H,15,29-30H2,1-11H3,(H,47,50,51)/t38-,40-,41-,42-,59?/m1/s1

Synonyms: 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 2'-CE phosphoramidite; 3'-TBDMS-rU Phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-2-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-3-O-(tert-butyl-dimethyl-silyl)-1-deoxy-1-uracil-1-yl-beta-D-ribo-pentofuranose; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 3'-OTBS U 2'-amidite; 3'-O-TBDMS-5'-O-DMT-rU CED phosphoramidite; DMT-3'-O-TBDMS-U-2'-CE-Phosphoramidite

2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite (BRP-02171)

Description: 2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite is a modified phosphoramidite used in the synthesis of oligonucleotides. This compound features a 2'-fluoro and 2'-deoxy modification on the arabinose sugar, a benzoyl (Bz) protective group on the nucleobase cytosine, and a phosphoramidite group at the 3' position. These modifications enhance the chemical stability and binding affinity of the resulting oligonucleotides, making them useful for applications in molecular biology, diagnostics, and therapeutic development.

CAT: BRP-02171

CAS: 1404463-12-2

Molecular Formula: C46H51FN5O8P

Molecular Weight: 851.90

Purity: ≥95%

Appearance: White to Off-white Powder

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Boiling Point: 856.5±75.0°C at 760 mmHg

InChIKey: CKKJPMGSTGVCJJ-OEJVQKCDSA-N

Solubility: Soluble in DMSO

CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1F)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC

IUPAC Name: N-[1-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-fluorooxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

Synonyms: N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-b-D-arabinocytidine-3'-CED-phosphoramidite; N4-Benzoyl-2'-fluoro-5'-O-DMT-2'-arabinofuranosyl-deoxycytidine phosphoramidite; 4-(Benzoylimino)-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-1,4-dihydro-2-pyrimidinol; N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytidine 3'-CE-phosphoramidite; 5'-O-DMTr-2'-ara-F-C(Bz)-3'-CE-Phosphoramidite; 2'-F-2'-ara-Bz-dC Phosphoramidite; 2'-F-dC(Bz)-ANA-CE Phosphoramidite; 2'-F-2'-ara-N4-Bz-dC phosphoramidite

9-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite (BRP-02172)

Description: The 9-(2'-Deoxy-5'-O-DMT-2'-fluoro-beta-D-arabinofuranosyl)-N2-isobutyrylguanine 3'-CE phosphoramidite has been proven effective against cancer.

CAT: BRP-02172

CAS: 1404463-20-2

Molecular Formula: C44H53FN7O8P

Molecular Weight: 857.93

Purity: ≥97% by HPLC

Appearance: White to Off-white Solid

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InChIKey: KJFUMXZZVYMQEU-SJIRJWTBSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)F

IUPAC Name: N-[9-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-fluorooxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C44H53FN7O8P/c1-27(2)40(53)49-43-48-39-37(41(54)50-43)47-26-51(39)42-36(45)38(60-61(58-24-12-23-46)52(28(3)4)29(5)6)35(59-42)25-57-44(30-13-10-9-11-14-30,31-15-19-33(55-7)20-16-31)32-17-21-34(56-8)22-18-32/h9-11,13-22,26-29,35-36,38,42H,12,24-25H2,1-8H3,(H2,48,49,50,53,54)/t35-,36+,38-,42-,61?/m1/s1

Synonyms: 5'-O-DMT-2'-fluoro-N2-isobutyryl-2'-arabinofuranosyl-deoxyguanosine 3'-CE phosphoramidite; 2'-F-2'-ara-N2-ibu-dG phosphoramidite; Propanamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methyl-; N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-fluoro-2'-arabinoguanosine-3'-CED-phosphoramidite; 9-{5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-2-(isobutyrylamino)-1,9-dihydro-6H-purin-6-one