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Phosphoramidites

2'-Modified Phosphoramidites
(549/549)
2'-Phosphoramidites
(27/27)
3'-Modified Phosphoramidites
(201/201)
5'-Modified Phosphoramidites
(34/34)
Arabino Phosphoramidites
(24/24)
Base Protected Phosphoramidites (435/435) Dye Phosphoramidites
(63/63)
Label Phosphoramidites
(81/81)
Linker Phosphoramidites
(97/97)
Other Phosphoramidites
(94/94)
PMO Phosphoramidates and Derivatives (33/33) PseudoUridine Phosphoramidite
(12/12)
Reverse Phosphoramidites
(25/25)
Spacer Phosphoramidites
(24/24)
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Biotin TEG Phosphoramidite (BRP-02214)

Description: Biotin TEG Phosphoramidite incorporates a biotin label with triethylene glycol spacer, either internally or at the 5' end of an oligonucleotide. Biotin is commonly used in detection systems in conjunction with streptavidin
CAT: BRP-02214
CAS: 198080-44-3
Molecular Formula: C52H76N5O11PS
Molecular Weight: 1010.24
Purity: ≥95% by NMR
Appearance: Off-white Solid
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Storage: Store at -20 °C
Boiling Point: 1018.0±65.0 °C at 760 mmHg
Symbol: BIOTIN-TEG CEP
Formulation: Dilute with anhydrous acetonitrile
InChIKey: JHOFQGWLXUQCDS-MPUKHDSVSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC(COCCOCCOCCOCCCNC(=O)CCCCC1C2C(CS1)NC(=O)N2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
IUPAC Name: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[3-[2-[2-[2-[3-[bis(4-methoxyphenyl)-phenylmethoxy]-2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropoxy]ethoxy]ethoxy]ethoxy]propyl]pentanamide
InChI: InChI=1S/C52H76N5O11PS/c1-39(2)57(40(3)4)69(67-29-12-26-53)68-46(37-66-52(41-14-8-7-9-15-41,42-18-22-44(60-5)23-19-42)43-20-24-45(61-6)25-21-43)36-65-35-34-64-33-32-63-31-30-62-28-13-27-54-49(58)17-11-10-16-48-50-47(38-70-48)55-51(59)56-50/h7-9,14-15,18-25,39-40,46-48,50H,10-13,16-17,27-38H2,1-6H3,(H,54,58)(H2,55,56,59)/t46?,47-,48-,50-,69?/m0/s1
Synonyms: 1-Dimethoxytrityloxy-3-O-(N-biotinyl-3-aminopropyl)-triethyleneglycolyl-glyceryl-2-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-3,6,9,12-tetraoxa-16-azaheneicos-1-yl 2-cyanoethyl ester; Phosphoramidous acid, bis(1-methylethyl)-, 1-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-21-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-17-oxo-3,6,9,12-tetraoxa-16-azaheneicos-1-yl 2-cyanoethyl ester, [3aS-(3aα,4β,6aα)]-[partial]-; Biotin-TEG CEP; Biotin TEG amidite; Biotin TEG CE Phosphoramidite

10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite (BRP-02215)

Description: 10-O-[1-Propyl-3-N-carbamoylcholesteryl]-TEG-CE phosphoramidite, an activator for viral RNA replication, is a specialized reagent used in the synthesis of modified oligonucleotides, particularly in the context of creating conjugated or functionalized nucleic acids. This reagent is particularly useful in the development of oligonucleotide-based drugs, where conjugation with lipophilic molecules like cholesterol can significantly improve the drug's performance.
CAT: BRP-02215
CAS: 1325147-19-0
Molecular Formula: C46H82N3O7P
Molecular Weight: 820.13
Purity: ≥95%
Appearance: Colorless oil to heavy oily matter
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Storage: Store at -20 °C
Boiling Point: 777.0±60.0 °C at 760 mmHg
InChIKey: XIXYNNLTICMGJD-CYNTUAGHSA-N
Solubility: Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
CanonicalSMILES: CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OC(=O)NCCCOCCOCCOCCOP(N(C(C)C)C(C)C)OCCC#N)C)C
IUPAC Name: [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] N-[3-[2-[2-[2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyethoxy]ethoxy]ethoxy]propyl]carbamate
InChI: InChI=1S/C46H82N3O7P/c1-34(2)13-10-14-37(7)41-17-18-42-40-16-15-38-33-39(19-21-45(38,8)43(40)20-22-46(41,42)9)56-44(50)48-24-12-25-51-27-28-52-29-30-53-31-32-55-57(54-26-11-23-47)49(35(3)4)36(5)6/h15,34-37,39-43H,10-14,16-22,24-33H2,1-9H3,(H,48,50)/t37-,39+,40+,41-,42+,43+,45+,46-,57?/m1/s1
Synonyms: 5'-Cholesterol-TEG-CE Phosphoramidite; 10-O-[1-Propyl-3-N-carbamoylcholesteryl]-triethyleneglycol-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Cholest-5-en-3-ol (3β)-, 3-[16-[bis(1-methylethyl)amino]-19-cyano-6,9,12,15,17-pentaoxa-2-aza-16-phosphanonadecanoate]; 5'-Cholesteryl TEG phosphoramidite

5'-Amino-Modifier C12 (BRP-02216)

Description: 5'-Amino Modifier is designed for use in automatic synthesizers to functionalize the sequence of the 5'end of the target oligonucleotide. The use of trityl-protected amino-modifiers is recommended when purification is required prior to use.
CAT: BRP-02216
CAS: 178925-51-4
Molecular Formula: C41H60N3O3P
Molecular Weight: 673.92
Purity: >95%
Appearance: Light-yellow oily matter
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Storage: Store at -20 °C
Boiling Point: 687.7±55.0 °C at 760 mmHg
Formulation: Dilute with anhydrous acetonitrile
InChIKey: VJLVUDQTXLCFHR-UHFFFAOYSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCCCCCCCNC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=C(C=C3)OC)OCCC#N
IUPAC Name: 3-[[di(propan-2-yl)amino]-[12-[[(4-methoxyphenyl)-diphenylmethyl]amino]dodecoxy]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C41H60N3O3P/c1-35(2)44(36(3)4)48(47-34-22-31-42)46-33-21-13-11-9-7-6-8-10-12-20-32-43-41(37-23-16-14-17-24-37,38-25-18-15-19-26-38)39-27-29-40(45-5)30-28-39/h14-19,23-30,35-36,43H,6-13,20-22,32-34H2,1-5H3
Synonyms: 5'-Amino-Modifier C12-MMTr CE Phosphoramidite; 12-(4-Monomethoxytritylamino)dodecyl-1-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl 12-[[(4-methoxyphenyl)diphenylmethyl]amino]dodecyl ester; MMT-C12-amine-linker Phosphoramidite; Monomethoxytrityl-C12-hexylamine-linker Phosphoramidite; 5'-Amino-Modifier C12 Phosphoramidite; 2-Cyanoethyl 12-[[(4-methoxyphenyl)diphenylmethyl]amino]dodecyl N,N-bis(1-methylethyl)phosphoramidite

Biotin Phosphoramidite (BRP-02217)

Description: Biotin Phosphoramidite is a reagent used to incorporate biotin into oligonucleotides during solid-phase synthesis. The biotin moiety, known for its strong affinity to streptavidin, allows for easy detection, purification, and immobilization of the modified oligonucleotides. This makes it a valuable tool in molecular biology for labeling, assays, and targeted delivery applications. Biotinylated oligonucleotides are commonly used in techniques such as ELISA, Western blotting, and nucleic acid hybridization, providing a versatile and efficient way to enhance the functionality of DNA and RNA sequences.
CAT: BRP-02217
CAS: 1217500-22-5
Molecular Formula: C46H64N5O8PS
Molecular Weight: 878.07
Purity: ≥96%
Appearance: Off-white powder
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Storage: Store at -20 °C
Boiling Point: 954.5±65.0 °C at 760 mmHg
Formulation: Dilute with anhydrous acetonitrile
InChIKey: WSDQYLGSIUJJRU-ZMKGMYJVSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OCCOCCOCCNC(=O)CCCCC1C2C(CS1)N(C(=O)N2)C(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC
IUPAC Name: 5-[(3aR,6S,6aS)-3-[bis(4-methoxyphenyl)-phenylmethyl]-2-oxo-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]-N-[2-[2-[2-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyethoxy]ethoxy]ethyl]pentanamide
InChI: InChI=1S/C46H64N5O8PS/c1-34(2)51(35(3)4)60(58-27-12-25-47)59-32-31-57-30-29-56-28-26-48-43(52)16-11-10-15-42-44-41(33-61-42)50(45(53)49-44)46(36-13-8-7-9-14-36,37-17-21-39(54-5)22-18-37)38-19-23-40(55-6)24-20-38/h7-9,13-14,17-24,34-35,41-42,44H,10-12,15-16,26-33H2,1-6H3,(H,48,52)(H,49,53)/t41-,42-,44-,60?/m0/s1
Synonyms: 1-Dimethoxytrityloxy-2-(N-biotinyl-4-aminobutyl)-propyl-3-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-[2-[2-[[5-[(3aS,4S,6aR)-1-[bis(4-methoxyphenyl)phenylmethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]ethyl 2-cyanoethyl ester; 2-[2-[2-[[5-[(3aS,4S,6aR)-1-[Bis(4-methoxyphenyl)phenylmethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethoxy]ethoxy]ethyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Biotin-amidite; DMTr-biotin-PEG3-(2-cyanoethyl) diisopropylphosphoramidite

5'-Biotin CE Phosphoramidite (BRP-02218)

Description: 5'-Biotin Phosphoramidite for direct labeling of synthetic oligonucleotides has the following characteristics:
  • Soluble in acetonitrile at concentrations useful for DNA synthesis.
  • Include the DMT group used for cassette purification, which is essential for the preparation of biotinylated PCR primers because cross-contamination may occur during HPLC purification.
  • To develop diagnostic probes, biotin phosphoramidite can be branched to allow the introduction of multiple biotins at the 3'or 5'end.
CAT: BRP-02218
CAS: 135137-87-0
Molecular Formula: C46H64N5O6PS
Molecular Weight: 846.08
Purity: >95% by HPLC
Appearance: Off-white Solid
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Storage: Store at -20 °C
Boiling Point: 934.9±65.0 °C at 760 mmHg
Symbol: DMT-Biotin-C6 Amidite
Formulation: Dilute with anhydrous acetonitrile
InChIKey: RBXYKQBFPLXSJS-RYQQVEDISA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)CCCCC1C2C(CS1)N(C(=O)N2)C(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OCCC#N
IUPAC Name: 5-[(3aR,6S,6aS)-3-[bis(4-methoxyphenyl)-phenylmethyl]-2-oxo-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl]-N-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]pentanamide
InChI: InChI=1S/C46H64N5O6PS/c1-34(2)51(35(3)4)58(57-32-16-29-47)56-31-15-8-7-14-30-48-43(52)20-13-12-19-42-44-41(33-59-42)50(45(53)49-44)46(36-17-10-9-11-18-36,37-21-25-39(54-5)26-22-37)38-23-27-40(55-6)28-24-38/h9-11,17-18,21-28,34-35,41-42,44H,7-8,12-16,19-20,30-33H2,1-6H3,(H,48,52)(H,49,53)/t41-,42-,44-,58?/m0/s1
Synonyms: DMT-Biotin-C6 Phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 6-[[5-[(3aS,4S,6aR)-1-[bis(4-methoxyphenyl)phenylmethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]hexyl 2-cyanoethyl ester; Phosphoramidous acid, bis(1-methylethyl)-, 6-[[5-[1-[bis(4-methoxyphenyl)phenylmethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]hexyl 2-cyanoethyl ester, [3aS-(3aα,4β,6aα)]-; 5'-Biotin Phosphoramidite; N1-(4,4'-Dimethoxytrityl)-biotinyl-6-aminohexyl]-2-cyanoethyl-(N,N-diisopropyl)-phosphoramidite

PC Biotin Phosphoramidite (BRP-02219)

Description: PC Biotin phosphoramidite can be used to prepare 5'-biotinylated oligonucleotides. After capturing the biotin-labeled DNA with streptavidin beads or attaching the modified DNA to the surface, the DNA can be released into the solution only by irradiating with a handheld ultraviolet light source.
CAT: BRP-02219
CAS: 853955-90-5
Molecular Formula: C55H72N7O9PS
Molecular Weight: 1038.25
Purity: >95%
Appearance: Light yellow solid
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Storage: Store at -20 °C
InChIKey: XSOZHGRMILVYEM-RNCGZCDESA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: N#CCCOP(OC(C1=CC(=CC=C1N(=O)=O)CNC(=O)CCCCCNC(=O)CCCCC2SCC3N(C(=O)NC23)C(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C)N(C(C)C)C(C)C
IUPAC Name: 1-(5-((6-(5-((3aS,4S,6aR)-1-(bis(4-methoxyphenyl)(phenyl)methyl)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)methyl)-2-nitrophenyl)ethyl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C55H72N7O9PS/c1-38(2)61(39(3)4)72(70-34-16-32-56)71-40(5)47-35-41(22-31-48(47)62(66)67)36-58-52(64)20-12-9-15-33-57-51(63)21-14-13-19-50-53-49(37-73-50)60(54(65)59-53)55(42-17-10-8-11-18-42,43-23-27-45(68-6)28-24-43)44-25-29-46(69-7)30-26-44/h8,10-11,17-18,22-31,35,38-40,49-50,53H,9,12-16,19-21,33-34,36-37H2,1-7H3,(H,57,63)(H,58,64)(H,59,65)/t40?,49-,50-,53-,72?/m0/s1
Synonyms: 1-[2-Nitro-5-(6-(N-(4,4'-dimethoxytrityl))-biotinamidocaproamidomethyl)phenyl]-ethyl-[2-cyanoethyl-(N,N-diisopropyl)]-phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 1-[5-[[[6-[[5-[(3aS,4S,6aR)-1-[bis(4-methoxyphenyl)phenylmethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-1-oxohexyl]amino]methyl]-2-nitrophenyl]ethyl 2-cyanoethyl ester

Phosphate-ON Phosphoramidite (BRP-02220)

Description: Phosphate-ON Phosphoramidite can be used to prepare 5'-phosphorylated oligonucleotides.
CAT: BRP-02220
CAS: 669013-14-3
Molecular Formula: C49H62N7O11P
Molecular Weight: 956.03
Purity: ≥96.0% (reversed phase HPLC)
Appearance: Solid
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Storage: Store at -20 °C
Symbol: Phosphate-ON amidite
InChIKey: MCGIOYZUTKDSIL-NNUNARBDSA-N
CanonicalSMILES: CC1=CN(C(=O)NC1=O)C2CC(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OC(=O)NCCCNC(=O)CC(CC#N)OP(N(C(C)C)C(C)C)OCCC#N
IUPAC Name: [(2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl] N-[3-[[(3R)-4-cyano-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxybutanoyl]amino]propyl]carbamate
InChI: InChI=1S/C49H62N7O11P/c1-33(2)56(34(3)4)68(64-28-11-24-50)67-41(23-25-51)29-44(57)52-26-12-27-53-48(60)66-42-30-45(55-31-35(5)46(58)54-47(55)59)65-43(42)32-63-49(36-13-9-8-10-14-36,37-15-19-39(61-6)20-16-37)38-17-21-40(62-7)22-18-38/h8-10,13-22,31,33-34,41-43,45H,11-12,23,26-30,32H2,1-7H3,(H,52,57)(H,53,60)(H,54,58,59)/t41-,42+,43-,45-,68?/m1/s1
Synonyms: (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (3-((3R)-4-cyano-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)butanamido)propyl)carbamate; Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 3'-[(9R)-11-[bis(1-methylethyl)amino]-14-cyano-9-(cyanomethyl)-7-oxo-10,12-dioxa-2,6-diaza-11-phosphatetradecanoate]

Amino-Modifier C6 dA (BRP-02221)

Description: Amino-Modifier C6 dA is designed for automatic synthesis. During oligonucleotide synthesis, the addition of the amino modifier dA can replace the dA residue to functionalize the target oligonucleotide.
CAT: BRP-02221
CAS: 1301170-09-1
Molecular Formula: C55H65F3N9O8P
Molecular Weight: 1068.14
Purity: ≥95%
Appearance: Crisp White Foam
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Storage: Store at 2-8 °C
InChIKey: GXRUEUPQLOMARL-QLBLUKILSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C6=NC=NC(=C6N=C5NCCCCCCNC(=O)C(F)(F)F)NC(=O)C7=CC=CC=C7
IUPAC Name: N-[9-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-8-[6-[(2,2,2-trifluoroacetyl)amino]hexylamino]purin-6-yl]benzamide
InChI: InChI=1S/C55H65F3N9O8P/c1-37(2)67(38(3)4)76(73-33-17-30-59)75-45-34-47(74-46(45)35-72-54(40-20-13-10-14-21-40,41-22-26-43(70-5)27-23-41)42-24-28-44(71-6)29-25-42)66-50-48(49(62-36-63-50)65-51(68)39-18-11-9-12-19-39)64-53(66)61-32-16-8-7-15-31-60-52(69)55(56,57)58/h9-14,18-29,36-38,45-47H,7-8,15-17,31-35H2,1-6H3,(H,60,69)(H,61,64)(H,62,63,65,68)/t45-,46+,47+,76?/m0/s1
Synonyms: 5'-Dimethoxytrityl-N6-benzoyl-N8-[6-(trifluoroacetylamino)-hex-1-yl]-8-amino-2'-deoxyadenosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-8-[[6-[(2,2,2-trifluoroacetyl)amino]hexyl]amino]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-DMTr-8-C6-linker-TFA-2'-deoxy-3'-O-CEP-adenosine; Amino Modifier C6-dA CE-Phosphoramidite

Amino-Modifier C6 dC (BRP-02222)

Description: Amino-Modifier C6 dC is designed for automatic synthesis. During oligonucleotide synthesis, the addition of the amino modifier dC can replace the dC residue to functionalize the target oligonucleotide.
CAT: BRP-02222
CAS: 853955-92-7
Molecular Formula: C53H68F3N8O9P
Molecular Weight: 1049.12
Purity: ≥95%
Appearance: Crisp white foam
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Storage: Store at 2-8 °C
InChIKey: BOZPQLMADZRBAJ-DDCNFULFSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=NC5=O)N=CN(C)C)C=CC(=O)NCCCCCCNC(=O)C(F)(F)F
IUPAC Name: 3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-4-(dimethylaminomethylideneamino)-2-oxopyrimidin-5-yl]-N-[6-[(2,2,2-trifluoroacetyl)amino]hexyl]prop-2-enamide
InChI: InChI=1S/C53H68F3N8O9P/c1-37(2)64(38(3)4)74(71-32-16-29-57)73-45-33-48(63-34-39(49(61-51(63)67)60-36-62(5)6)19-28-47(65)58-30-14-9-10-15-31-59-50(66)53(54,55)56)72-46(45)35-70-52(40-17-12-11-13-18-40,41-20-24-43(68-7)25-21-41)42-22-26-44(69-8)27-23-42/h11-13,17-28,34,36-38,45-46,48H,9-10,14-16,30-33,35H2,1-8H3,(H,58,65)(H,59,66)/t45-,46+,48+,74?/m0/s1
Synonyms: Amino-modifier-C6-dC Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-N-[(dimethylamino)methylene]-5-[(1E)-3-oxo-3-({6-[(trifluoroacetyl)amino]hexyl}amino)-1-propen-1-yl]cytidine; 5'-Dimethoxytrityl-N-dimethylformamidine-5-[N-(trifluoroacetylaminohexyl)-3-acrylimido]-2'-deoxycytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Amino-Modifier C6 dC CEP; Amino-modifier-C6-dC-CE-Phosphoramidite; Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[(dimethylamino)methylene]-5-[3-oxo-3-[[6-[(trifluoroacetyl)amino]hexyl]amino]-1-propenyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

Amino-Modifier C6 dT (BRP-02223)

Description: Amino-Modifier C6 dT is designed for automatic synthesis. During oligonucleotide synthesis, the addition of the amino modifier dT can replace the dT residue to functionalize the target oligonucleotide.
CAT: BRP-02223
CAS: 178925-21-8
Molecular Formula: C50H62N6O10F3P
Molecular Weight: 995.05
Purity: ≥95%
Appearance: White to off-white powder
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Storage: Store at -20 °C, Keep in a dark and dry place
Formulation: Dilute with anhydrous acetonitrile
InChIKey: XHGOWDJUVKONLU-DCHZGMOKSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C=CC(=O)NCCCCCCNC(=O)C(F)(F)F
IUPAC Name: 3-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2,4-dioxopyrimidin-5-yl]-N-[6-[(2,2,2-trifluoroacetyl)amino]hexyl]prop-2-enamid
InChI: InChI=1S/C50H62F3N6O10P/c1-34(2)59(35(3)4)70(67-30-14-27-54)69-42-31-45(58-32-36(46(61)57-48(58)63)17-26-44(60)55-28-12-7-8-13-29-56-47(62)50(51,52)53)68-43(42)33-66-49(37-15-10-9-11-16-37,38-18-22-40(64-5)23-19-38)39-20-24-41(65-6)25-21-39/h9-11,15-26,32,34-35,42-43,45H,7-8,12-14,28-31,33H2,1-6H3,(H,55,60)(H,56,62)(H,57,61,63)/t42-,43+,45+,70?/m0/s1
Synonyms: 5'-Dimethoxytrityl-5-[N-(trifluoroacetylaminohexyl)-3-acrylimido]-2'-deoxyuridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[3-oxo-3-[[6-[(2,2,2-trifluoroacetyl)amino]hexyl]amino]-1-propen-1-yl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[3-oxo-3-[[6-[(trifluoroacetyl)amino]hexyl]amino]-1-propenyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; Trifluoroacetyl Amino-Modifier C6 dT
Related CAS: 210534-16-0 (E-isomer)

N2-Amino-Modifier C6 dG (BRP-02224)

Description: N2-Amino-Modifier C6 dG is designed for automatic synthesis. During oligonucleotide synthesis, the addition of the amino modifier dG can replace the dG residue to functionalize the target oligonucleotide.
CAT: BRP-02224
CAS: 1810776-99-8
Molecular Formula: C48H60F3N8O8P
Molecular Weight: 965.01
Purity: ≥95%
Appearance: Crisp Off-White Foam
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Storage: Store at 2-8 °C
InChIKey: LCMSIWHSYYDELA-AYXHSPLSSA-N
CanonicalSMILES: N#CCCOP(OC1CC(OC1COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C=NC=6C(=O)N=C(NC65)NCCCCCCNC(=O)C(F)(F)F)N(C(C)C)C(C)C
IUPAC Name: (2R,3S,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-oxo-2-((6-(2,2,2-trifluoroacetamido)hexyl)amino)-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
InChI: InChI=1S/C48H60F3N8O8P/c1-32(2)59(33(3)4)68(65-28-14-25-52)67-39-29-41(58-31-55-42-43(58)56-46(57-44(42)60)54-27-13-8-7-12-26-53-45(61)48(49,50)51)66-40(39)30-64-47(34-15-10-9-11-16-34,35-17-21-37(62-5)22-18-35)36-19-23-38(63-6)24-20-36/h9-11,15-24,31-33,39-41H,7-8,12-14,26-30H2,1-6H3,(H,53,61)(H2,54,56,57,60)/t39-,40+,41+,68?/m0/s1
Synonyms: 5'-Dimethoxytrityl-N2-[6-(trifluoroacetylamino)-hex-1-yl]-2'-deoxyguanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[6-[(2,2,2-trifluoroacetyl)amino]hexyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

PC Amino-Modifier Phosphoramidite (BRP-02225)

Description: PC Amino-Modifier Phosphoramidite is can be incorporated into DNA and RNA with both phosphate and phosphorothioate linkages, used to prepare 5'-amino-modified oligonucleotides suitable for subsequent photocleavage.
CAT: BRP-02225
CAS: 732298-96-3
Molecular Formula: C26H39F3N5O6P
Molecular Weight: 605.59
Purity: ≥95%
Appearance: Colorless to light yellow oily matter
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Storage: Store at -20 °C
InChIKey: DSRDGAPERUUCRW-UHFFFAOYSA-N
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: N#CCCOP(OC(C1=CC(=CC=C1N(=O)=O)CNC(=O)CCCCCNC(=O)C(F)(F)F)C)N(C(C)C)C(C)C
IUPAC Name: 2-cyanoethyl (1-(2-nitro-5-((6-(2,2,2-trifluoroacetamido)hexanamido)methyl)phenyl)ethyl) diisopropylphosphoramidite
InChI: InChI=1S/C26H39F3N5O6P/c1-18(2)33(19(3)4)41(39-15-9-13-30)40-20(5)22-16-21(11-12-23(22)34(37)38)17-32-24(35)10-7-6-8-14-31-25(36)26(27,28)29/h11-12,16,18-20H,6-10,14-15,17H2,1-5H3,(H,31,36)(H,32,35)
Synonyms: Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 1-[2-nitro-5-[[[1-oxo-6-[(trifluoroacetyl)amino]hexyl]amino]methyl]phenyl]ethyl ester; [(6-Trifluoroacetylamidocaproamidomethyl)-1-(2-nitrophenyl)-ethyl]-2-cyanoethyl-(N,N-diisopropyl)-phosphoramidite; PC 5'-Amino modifier-CE-Phoshoramidite

Thiol-Modifier C6 S-S (BRP-02226)

Description: Thiol-Modifier C6 S-S incorporates a thiol reactive functional group for conjugation. This disulphide product can also be used to modify the 3'-position by using the phosphoramidite as the first adduct in the oligo sequence.
CAT: BRP-02226
CAS: 148254-21-1
Molecular Formula: C42H61N2O5S2P
Molecular Weight: 769.05
Purity: >95% by HPLC
Appearance: Colorless oily matter
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Storage: Store at -20 °C
Boiling Point: 757.4±60.0 °C at 760 mmHg
InChIKey: VEONRKLBSGQZRU-UHFFFAOYSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCSSCCCCCCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)OCCC#N
IUPAC Name: 3-[6-[6-[bis(4-methoxyphenyl)-phenylmethoxy]hexyldisulfanyl]hexoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
InChI: InChI=1S/C42H61N2O5PS2/c1-35(2)44(36(3)4)50(49-32-18-29-43)48-31-15-8-10-17-34-52-51-33-16-9-7-14-30-47-42(37-19-12-11-13-20-37,38-21-25-40(45-5)26-22-38)39-23-27-41(46-6)28-24-39/h11-13,19-28,35-36H,7-10,14-18,30-34H2,1-6H3
Synonyms: 1-O-Dimethoxytrityl-hexyl-disulfide, 1'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Thiol-Modifier C6 S-S CE Phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 6-[[6-[bis(4-methoxyphenyl)phenylmethoxy]hexyl]dithio]hexyl 2-cyanoethyl ester; N,N-Bis(1-methylethyl)phosphoramidous Acid [[6-[Bis(4-methoxyphenyl)phenylmethoxy]hexyl]dithio]hexyl 2-Cyanoethylester; 6-[[6-[Bis(4-methoxyphenyl)phenylmethoxy]hexyl]dithio]hexyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite

5'-(5-Fluorescein) phosphoramidite (BRP-02227)

Description: A fluorescein phosphoramidite for oligonucleotide labeling and DNA synthesis. Ideal for molecular biology and fluorescence probe development.
CAT: BRP-02227
CAS: 147566-42-5
Molecular Formula: C46H58N3O10P
Molecular Weight: 843.94
Purity: >95%
Appearance: White to off-white solid
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Storage: Store at -20 °C
Boiling Point: 844.7±65.0 °C at 760 mmHg
Symbol: 5-FAM
InChIKey: XUQUNBOKLNVMMK-UHFFFAOYSA-N
Fluorescence Maximum: 517
Absorption Maximum (Lambda Max): 492
Solubility: Soluble in Acetonitrile, DCM
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)C1=CC2=C(C=C1)C3(C4=C(C=C(C=C4)OC(=O)C(C)(C)C)OC5=C3C=CC(=C5)OC(=O)C(C)(C)C)OC2=O)OCCC#N
IUPAC Name: [5-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C46H58N3O10P/c1-29(2)49(30(3)4)60(55-25-15-22-47)54-24-14-12-11-13-23-48-40(50)31-16-19-35-34(26-31)41(51)59-46(35)36-20-17-32(56-42(52)44(5,6)7)27-38(36)58-39-28-33(18-21-37(39)46)57-43(53)45(8,9)10/h16-21,26-30H,11-15,23-25H2,1-10H3,(H,48,50)
Synonyms: 5-FAM phosphoramidite; 5-Fluorescein Phosphoramidite; 5'(5)-FAM; 5'-5-Fluorescein phosphoramidite; FAM Phosphoramidite, 5-Isomer; Propanoic acid, 2,2-dimethyl-, 5-[10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; Fluorescein Phosphoramidite

5'-Dabcyl Phosphoramidite (BRP-02229)

Description: A dark quencher phosphoramidite for oligonucleotide synthesis and FRET probes. Buy this high-purity reagent for molecular beacon construction.
CAT: BRP-02229
CAS: 288631-58-3
Molecular Formula: C30H45N6O3P
Molecular Weight: 568.69
Purity: >95%
Appearance: Sticky orange solid
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Storage: Store at -20 °C
Boiling Point: 680.0±55.0 °C at 760 mmHg
Symbol: 5'-DABCYL CEP
Formulation: Dilute with anhydrous acetonitrile
InChIKey: RBMLVVGBOLZOAB-UHFFFAOYSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)C1=CC=C(C=C1)N=NC2=CC=C(C=C2)N(C)C)OCCC#N
IUPAC Name: N-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexyl]-4-[[4-(dimethylamino)phenyl]diazenyl]benzamide
InChI: InChI=1S/C30H45N6O3P/c1-24(2)36(25(3)4)40(39-23-11-20-31)38-22-10-8-7-9-21-32-30(37)26-12-14-27(15-13-26)33-34-28-16-18-29(19-17-28)35(5)6/h12-19,24-25H,7-11,21-23H2,1-6H3,(H,32,37)
Synonyms: 5'-DABCYL CEP; 6-(N-4'-carboxy-4-(dimethylamino)azobenzene)-aminohexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 2-cyanoethyl 6-[[4-[[4-(dimethylamino)phenyl]azo]benzoyl]amino]hexyl ester; 2-cyanoethyl (6-(4-((4-(dimethylamino)phenyl)diazenyl)benzamido)hexyl) diisopropylphosphoramidite

Fluorescein 2'-deoxy-5'-O-DMT-pseudouridine 3'-CE phosphoramidite (BRP-02231)

Description: This fluorescein-modified phosphoramidite enables site-specific fluorescent labeling of RNA during synthesis. It yields bright green emission for nucleic acid detection.
CAT: BRP-02231
CAS: 289712-99-8
Molecular Formula: C79H89N6O17P
Molecular Weight: 1425.57
Purity: ≥95%
Appearance: Off-white powder
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Storage: Store at 2-8 °C
InChIKey: WHVKLEUMJJAXRZ-PCLSEREPSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)C5=CN(C(=O)NC5=O)C=CC(=O)NCCCCCCNC(=O)C6=CC7=C(C=C6)C8(C9=C(C=C(C=C9)OC(=O)C(C)(C)C)OC1=C8C=CC(=C1)OC(=O)C(C)(C)C)OC7=O
IUPAC Name: [5-[6-[3-[5-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-2,4-dioxopyrimidin-1-yl]prop-2-enoylamino]hexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C79H89N6O17P/c1-49(2)85(50(3)4)103(96-42-20-38-80)102-67-46-64(99-68(67)48-95-78(52-21-16-15-17-22-52,53-24-28-55(93-11)29-25-53)54-26-30-56(94-12)31-27-54)60-47-84(75(92)83-71(60)88)41-37-69(86)81-39-18-13-14-19-40-82-70(87)51-23-34-61-59(43-51)72(89)101-79(61)62-35-32-57(97-73(90)76(5,6)7)44-65(62)100-66-45-58(33-36-63(66)79)98-74(91)77(8,9)10/h15-17,21-37,41,43-45,47,49-50,64,67-68H,13-14,18-20,39-40,42,46,48H2,1-12H3,(H,81,86)(H,82,87)(H,83,88,92)/t64-,67+,68-,103?/m1/s1
Synonyms: Propanoic acid, 2,2-dimethyl-, 5-[[[6-[[3-[5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl]-1-oxo-2-propenyl]amino]hexyl]amino]carbonyl]-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; Fluorescein-deoxy-pU Phosphoramidite; Fluorescein 5-methyl-2'-deoxy-5'-O-DMT-pseudouridine 3'-CE phosphoramidite; 6-Fluorescein 5-methyl-2'-deoxy-5'-O-DMT-pseudouridine 3'-CE phosphoramidite
Related CAS: 1194507-30-6 (6-Fluorescein dT phosphoramidite)

5-SIMA phosphoramidite (BRP-02232)

Description: A SIMA quencher phosphoramidite for oligonucleotide synthesis and qPCR probes. Build high-performance molecular beacons and FRET assays with reliable dark quenching.
CAT: BRP-02232
Molecular Formula: C58H64Cl2N3O10P
Molecular Weight: 1065.02
Purity: >95%
Appearance: Soild
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Storage: Store at -20 °C
Formulation: Dilute with anhydrous acetonitrile
InChIKey: DRMXDUCOFIXGTJ-UHFFFAOYSA-N
IUPAC Name: 4,7-dichloro-5-((6-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)hexyl)carbamoyl)-3-oxo-2',7'-diphenyl-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)
InChI: InChI=1S/C58H64Cl2N3O10P/c1-35(2)63(36(3)4)74(69-29-21-26-61)68-28-20-12-11-19-27-62-52(64)41-32-44(59)50-49(51(41)60)53(65)73-58(50)42-30-39(37-22-15-13-16-23-37)45(71-54(66)56(5,6)7)33-47(42)70-48-34-46(72-55(67)57(8,9)10)40(31-43(48)58)38-24-17-14-18-25-38/h13-18,22-25,30-36H,11-12,19-21,27-29H2,1-10H3,(H,62,64)

6-Tetrachloro-Fluorescein Phosphoramidite (BRP-02233)

Description: This high-purity fluorescent phosphoramidite dye enables efficient DNA and RNA labeling with exceptional signal intensity. Choose our fluorescent probe supplier platform to buy fluorescent dyes online for genetic analysis and FRET experiments.
CAT: BRP-02233
CAS: 877049-90-6
Molecular Formula: C46H54N3O10Cl4P
Molecular Weight: 981.72
Purity: ≥95%
Appearance: White to off-white powder
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Storage: Store at -20 °C
Boiling Point: 895.1±65.0 °C at 760 mmHg
Symbol: 6-TET Phosphoramidite; 5'-Tetrachloro-Fluorescein-CE Phosphoramidite (TET)
InChIKey: RKVIHIDUTMZQEZ-UHFFFAOYSA-N
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)C1=CC(=C2C(=C1Cl)C3(C4=CC(=C(C=C4OC5=CC(=C(C=C53)Cl)OC(=O)C(C)(C)C)OC(=O)C(C)(C)C)Cl)OC2=O)Cl)OCCC#N
IUPAC Name: [2',4,7,7'-tetrachloro-6-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C46H54Cl4N3O10P/c1-25(2)53(26(3)4)64(59-19-15-16-51)58-18-14-12-11-13-17-52-40(54)27-20-32(49)37-38(39(27)50)46(63-41(37)55)28-21-30(47)35(61-42(56)44(5,6)7)23-33(28)60-34-24-36(31(48)22-29(34)46)62-43(57)45(8,9)10/h20-26H,11-15,17-19H2,1-10H3,(H,52,54)
Synonyms: DyLight TET CEP; Propanoic acid, 2,2-dimethyl-, 6-[10-[bis(1-methylethyl)amino]-13-cyano-1-oxo-9,11-dioxa-2-aza-10-phosphatridec-1-yl]-2',4,7,7'-tetrachloro-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-3',6'-diyl ester; 6-TET Phosphoramidite; TET phosphoramidite, 6-isomer; 6-(4,7,2',7'-Tetrachloro-3',6'-dipivaloylfluoresceinyl-6-carboxamido)-hexyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

Cyanine 5.5 Phosphoramidite (BRP-02236)

Description: Cyanine 5.5 Phosphoramidite offers deeper red emission for multiplex fluorescence assays and molecular imaging. This reliable labeling dye delivers high signal-to-noise performance for advanced bioanalysis.
CAT: BRP-02236
CAS: 916753-58-7
Molecular Formula: C68H76IN4O4P
Molecular Weight: 1171.24
Purity: ≥95%
Appearance: Blue Solid
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Storage: Store at -20 °C
Symbol: Cy5.5 Phosphoramidite
InChIKey: HUHDLWQCBHNBPG-UHFFFAOYSA-M
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC(C)N(C(C)C)P(OCCC[N+]1=C(C(C2=C1C=CC3=CC=CC=C32)(C)C)C=CC=CC=C4C(C5=C(N4CCCOC(C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=C(C=C8)OC)C=CC9=CC=CC=C95)(C)C)OCCC#N.[I-]
IUPAC Name: 3-[[di(propan-2-yl)amino]-[3-[2-[5-[3-[3-[(4-methoxyphenyl)-diphenylmethoxy]propyl]-1,1-dimethylbenzo[e]indol-2-ylidene]penta-1,3-dienyl]-1,1-dimethylbenzo[e]indol-3-ium-3-yl]propoxy]phosphanyl]oxypropanenitrile;iodide
InChI: InChI=1S/C68H76N4O4P.HI/c1-50(2)72(51(3)4)77(75-48-23-44-69)76-49-25-46-71-61-43-37-53-27-20-22-33-59(53)65(61)67(7,8)63(71)35-18-12-17-34-62-66(5,6)64-58-32-21-19-26-52(58)36-42-60(64)70(62)45-24-47-74-68(54-28-13-10-14-29-54,55-30-15-11-16-31-55)56-38-40-57(73-9)41-39-56;/h10-22,26-43,50-51H,23-25,45-49H2,1-9H3;1H/q+1;/p-1
Synonyms: 1-[3-(4-monomethoxytrityloxy)propyl]-1'-[3-[(2-cyanoethyl)-(N,N-diisopropyl)phosphoramidityl]propyl]-3,3,3',3'-tetramethyl-4,5-benzindodicarbocyanine iodide; 1H-Benz[e]indolium, 2-[5-[3-[3-[[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]propyl]-1,3-dihydro-1,1-dimethyl-2H-benz[e]indol-2-ylidene]-1,3-pentadien-1-yl]-3-[3-[(4-methoxyphenyl)diphenylmethoxy]propyl]-1,1-dimethyl-, iodide (1:1); Cy5.5 Phosphoramidite
Related CAS: 791569-89-6 (free base)

6-JOE phosphoramidite (BRP-02237)

Description: A JOE phosphoramidite for direct 5′ DNA/RNA labeling in synthesis. Ideal for qPCR probes, SNP assays, and multiplex detection.
CAT: BRP-02237
Molecular Formula: C48H60Cl2N3O12P
Molecular Weight: 972.88
Purity: ≥95%
Appearance: White solid
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Storage: Store at -20 °C
InChIKey: CKBMUCQWGUZAKQ-UHFFFAOYSA-N
Fluorescence Maximum: 554
Absorption Maximum (Lambda Max): 533
Solubility: Soluble in Anhydrous Acetonitrile
CanonicalSMILES: CC(C)N(C(C)C)P(OCCCCCCNC(=O)C1=CC2=C(C=C1)C(=O)OC23C4=CC(=C(C(=C4OC5=C(C(=C(C=C35)OC)OC(=O)C(C)(C)C)Cl)Cl)OC(=O)C(C)(C)C)OC)OCCC#N
IUPAC Name: [4',5'-dichloro-6-[6-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyhexylcarbamoyl]-6'-(2,2-dimethylpropanoyloxy)-2',7'-dimethoxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl] 2,2-dimethylpropanoate
InChI: InChI=1S/C48H60Cl2N3O12P/c1-27(2)53(28(3)4)66(61-23-17-20-51)60-22-16-14-13-15-21-52-42(54)29-18-19-30-31(24-29)48(65-43(30)55)32-25-34(58-11)40(63-44(56)46(5,6)7)36(49)38(32)62-39-33(48)26-35(59-12)41(37(39)50)64-45(57)47(8,9)10/h18-19,24-28H,13-17,21-23H2,1-12H3,(H,52,54)
Synonyms: 6-(4',5'-Dichloro-2',7'-dimethoxy-3',6'-dipivaloylfluorescein-6-carboxamido)-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; 5'-Dichloro-dimethoxy-Fluorescein Phosphoramidite II (Joe II); JOE phosphoramidite, 6-isomer; 5-Carboxy-2',7'-dimethoxy-4',5'-dichloro-fluoresceinamide phosphoramidite; 4',5'-dichloro-6-((6-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)hexyl)carbamoyl)-2',7'-dimethoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2,2-dimethylpropanoate)
* Only for research. Not suitable for any diagnostic or therapeutic use.

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