PC Spacer Phosphoramidite - CAS 653575-45-2

Catalog number: BRI-011

PC Spacer phosphoramidite can be used as an intermediate to link any modification reagent (which can be used as phosphoramidite) to the end of the oligonucleotide. After light cleavage, 5'-phosphate is generated on the DNA, making it suitable for further biotransformation, such as gene construction and cloning after ligation.

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Ordering Information
Catalog Number Size Price Stock Quantity
BRI-011 250 mg $499 In stock
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Synonyms
[4-(4,4'-Dimethoxytrityloxy)butyramidomethyl)-1-(2-nitrophenyl)-ethyl]-2-cyanoethyl-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 1-[5-[[[4-[bis(4-methoxyphenyl)phenylmethoxy]-1-oxobutyl]amino]methyl]-2-nitrophenyl]ethyl 2-cyanoethyl ester; 1-[5-[[[4-[Bis(4-methoxyphenyl)phenylmethoxy]-1-oxobutyl]amino]methyl]-2-nitrophenyl]ethyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, 1-[5-[[[4-[bis(4-methoxyphenyl)phenylmethoxy]-1-oxobutyl]amino]methyl]-2-nitrophenyl]ethyl 2-cyanoethyl ester
CAS
653575-45-2
IUPAC Name
1-(5-((4-(bis(4-methoxyphenyl)(phenyl)methoxy)butanamido)methyl)-2-nitrophenyl)ethyl (2-cyanoethyl) diisopropylphosphoramidite
Molecular Weight
784.88
Molecular Formula
C43H53N4O8P
Canonical SMILES
N#CCCOP(OC(C1=CC(=CC=C1N(=O)=O)CNC(=O)CCCOC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)C)N(C(C)C)C(C)C
InChI
InChI=1S/C43H53N4O8P/c1-31(2)46(32(3)4)56(54-28-12-26-44)55-33(5)40-29-34(16-25-41(40)47(49)50)30-45-42(48)15-11-27-53-43(35-13-9-8-10-14-35,36-17-21-38(51-6)22-18-36)37-19-23-39(52-7)24-20-37/h8-10,13-14,16-25,29,31-33H,11-12,15,27-28,30H2,1-7H3,(H,45,48)
InChIKey
KYVUUUIHEDGDBA-UHFFFAOYSA-N
Appearance
Off-white to yellow powder
Storage
Store at -20°C
Formulation
Dilute with anhydrous acetonitrile

Chemical Structure:

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