Nucleosides - RNA / BOC Sciences

N4-Dibutylformamidine-2'-fluoro-deoxycytidine

Description: N4-Dibutylformamidine-2'-fluoro-deoxycytidine is a modified deoxycytidine nucleoside featuring a dibutylformamidine group at the N4 position and a 2'-fluoro modification on the deoxyribose sugar, enhancing stability and enzymatic resistance in oligonucleotide synthesis, crucial for biomedical applications like gene therapy and molecular diagnostics.

CAT: BRP-01564

MF: C18H29FN4O4

MF: 384.45

Purity: ≥95% by HPLC

Appearance: White powder

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Storage: Store at 2-8 °C, Keep in a dark and dry place

InChIKey: LALGLRQWGPDIIJ-MWQQHZPXSA-N

IUPAC Name: N,N-dibutyl-N'-(1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)formimidamide

InChI: InChI=1S/C18H29FN4O4/c1-3-5-8-22(9-6-4-2)12-20-14-7-10-23(18(26)21-14)17-15(19)16(25)13(11-24)27-17/h7,10,12-13,15-17,24-25H,3-6,8-9,11H2,1-2H3/t13-,15-,16-,17-/m1/s1

Synonyms: N4-dibutylformamidine-2'-F-dC

N2-Dibutylformamidine-2'-fluoro-guanosine

Description: N2-Dibutylformamidine-2'-fluoro-guanosine is a modified guanosine nucleoside with a dibutylformamidine group attached to the N2 position and a 2'-fluoro modification on the ribose, enhancing stability and enzymatic resistance in oligonucleotide synthesis, crucial for biomedical applications like gene therapy and molecular diagnostics.

CAT: BRP-01565

MF: C19H29FN6O4

MF: 424.48

Purity: ≥95% by HPLC

Appearance: White powder

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Storage: Store at 2-8 °C, Keep in a dark and dry place

InChIKey: XMWCLGNFTGLYEX-HOPMXRPOSA-N

IUPAC Name: N,N-dibutyl-N'-(9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)formimidamide

InChI: InChI=1S/C19H29FN6O4/c1-3-5-7-25(8-6-4-2)10-22-19-23-16-14(17(29)24-19)21-11-26(16)18-13(20)15(28)12(9-27)30-18/h10-13,15,18,27-28H,3-9H2,1-2H3,(H,23,24,29)/t12-,13-,15-,18-/m1/s1

Synonyms: N2-dibutylformamidine-2'-F-Gr

N2-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-deoxyguanosine

Description: N2-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-deoxyguanosine is a modified deoxyguanosine nucleoside with an acetyl group at the N2 position and a 2'-fluoro modification on the deoxyribose sugar, protected by a 4,4'-dimethoxytrityl (DMTr) group at the 5'-hydroxyl. This modification enhances stability and enzymatic resistance in oligonucleotide synthesis, essential for biomedical applications such as gene therapy and molecular diagnostics.

CAT: BRP-01566

CAS: 514830-14-9

MF: C33H32FN5O7

MF: 629.63

Purity: ≥95% by HPLC

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Storage: Store at 2-8 °C, Keep in a dark and dry place

InChIKey: JKJYAEOBEUHFSL-IAHIMPAPSA-N

CanonicalSMILES: CC(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)F

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]acetamide

InChI: InChI=1S/C33H32FN5O7/c1-19(40)36-32-37-29-27(30(42)38-32)35-18-39(29)31-26(34)28(41)25(46-31)17-45-33(20-7-5-4-6-8-20,21-9-13-23(43-2)14-10-21)22-11-15-24(44-3)16-12-22/h4-16,18,25-26,28,31,41H,17H2,1-3H3,(H2,36,37,38,40,42)/t25-,26-,28-,31-/m1/s1

Synonyms: N2-Ac-DMT-2'-F-dG; N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide; Guanosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-; N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoroguanosine

N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-3'-O-succinate-2'-fluoro-deoxyguanosine, triethylamine salt

Description: N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-3'-O-succinate-2'-fluoro-deoxyguanosine, triethylamine salt is a modified deoxyguanosine nucleoside. It features an isobutyryl group at the N2 position, a 4,4'-dimethoxytrityl (DMTr) group at the 5'-hydroxyl, a succinate ester at the 3'-hydroxyl, and a 2'-fluoro modification on the deoxyribose sugar. This compound, in its triethylamine salt form, enhances stability and enzymatic resistance in oligonucleotide synthesis, crucial for applications such as gene therapy and molecular diagnostics.

CAT: BRP-01572

MF: C45H55FN6O10

MF: 858.95

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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InChIKey: JAFGAGVWXBMKKQ-KYJIEUEGSA-N

CanonicalSMILES: O=C1N=C(NC(=O)C(C)C)NC2=C1N=CN2C3OC(COC(C=4C=CC=CC4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)C(OC(=O)CCC(=O)O)C3F.N(CC)(CC)CC

IUPAC Name: 4-(((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluoro-5-(2-isobutyramido-6-oxo-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine

InChI: InChI=1S/C39H40FN5O10.C6H15N/c1-22(2)35(49)43-38-42-34-32(36(50)44-38)41-21-45(34)37-31(40)33(55-30(48)19-18-29(46)47)28(54-37)20-53-39(23-8-6-5-7-9-23,24-10-14-26(51-3)15-11-24)25-12-16-27(52-4)17-13-25;1-4-7(5-2)6-3/h5-17,21-22,28,31,33,37H,18-20H2,1-4H3,(H,46,47)(H2,42,43,44,49,50);4-6H2,1-3H3/t28-,31-,33-,37-;/m1./s1

Synonyms: N2-iBu-DMT-2'-F-dG-3'-succinate, TEA salt; 5'-DMT-2'-F-dG(iBu)-3'-succinate, TEA salt; 5'-DMT-NIBu-2'-F-dG-3'-succinate, TEA salt; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-fluoro-deoxyguanosine-3'-O-succinate, triethylamine salt

N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-succinate-2'-fluoro-deoxyadenosine, triethylamine salt

Description: N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-succinate-2'-fluoro-deoxyadenosine, triethylamine salt is a modified deoxyadenosine nucleoside. It features a benzoyl group at the N6 position, a 4,4'-dimethoxytrityl (DMTr) group at the 5'-hydroxyl, a succinate ester at the 3'-hydroxyl, and a 2'-fluoro modification on the deoxyribose sugar. This compound, in its triethylamine salt form, enhances stability and enzymatic resistance in oligonucleotide synthesis, crucial for applications such as gene therapy and molecular diagnostics.

CAT: BRP-01573

MF: C48H53FN6O9

MF: 876.97

Purity: ≥98% by HPLC

Appearance: White to yellow powder

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Storage: Store at 2-8 °C

InChIKey: RVRGUAZPBXTGSP-ARCYALSHSA-N

CanonicalSMILES: O=C(O)CCC(=O)OC1C(F)C(OC1COC(C=2C=CC=CC2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)N5C=NC=6C(=NC=NC65)NC(=O)C=7C=CC=CC7.N(CC)(CC)CC

IUPAC Name: 4-(((2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl)oxy)-4-oxobutanoic acid;N,N-diethylethanamine

InChI: InChI=1S/C42H38FN5O9.C6H15N/c1-53-30-17-13-28(14-18-30)42(27-11-7-4-8-12-27,29-15-19-31(54-2)20-16-29)55-23-32-37(57-34(51)22-21-33(49)50)35(43)41(56-32)48-25-46-36-38(44-24-45-39(36)48)47-40(52)26-9-5-3-6-10-26;1-4-7(5-2)6-3/h3-20,24-25,32,35,37,41H,21-23H2,1-2H3,(H,49,50)(H,44,45,47,52);4-6H2,1-3H3/t32-,35-,37-,41-;/m1./s1

Synonyms: N6-Bz-DMT-2'-F-dA-3'-succinate, TEA salt; 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenoisne-3'-O-succinate, triethylamine salt; 5'-DMT-NBz-2'-dA-3'-succinate, TEA salt

N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-succinate-2'-fluoro-deoxycytidine, triethylamine salt

Description: N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-succinate-2'-fluoro-deoxycytidine, triethylamine salt is a modified deoxycytidine nucleoside. It features an acetyl group at the N4 position, a 4,4'-dimethoxytrityl (DMTr) group at the 5'-hydroxyl, a succinate ester at the 3'-hydroxyl, and a 2'-fluoro modification on the deoxyribose sugar. This compound, in its triethylamine salt form, enhances stability and enzymatic resistance in oligonucleotide synthesis, crucial for applications such as gene therapy and molecular diagnostics.

CAT: BRP-01574

MF: C42H51FN4O10

MF: 790.87

Purity: ≥98% by HPLC

Appearance: White to yellow powder

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Storage: Store at 2-8 °C

InChIKey: GGLFHSJASYEZGI-PBJRKIRISA-N

CanonicalSMILES: CCN(CC)CC.CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)OC(=O)CCC(=O)O)F

IUPAC Name: 4-[(2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-fluorooxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

InChI: InChI=1S/C36H36FN3O10.C6H15N/c1-22(41)38-29-19-20-40(35(45)39-29)34-32(37)33(50-31(44)18-17-30(42)43)28(49-34)21-48-36(23-7-5-4-6-8-23,24-9-13-26(46-2)14-10-24)25-11-15-27(47-3)16-12-25;1-4-7(5-2)6-3/h4-16,19-20,28,32-34H,17-18,21H2,1-3H3,(H,42,43)(H,38,39,41,45);4-6H2,1-3H3/t28-,32-,33-,34-;/m1./s1

Synonyms: N4-Ac-DMT-2'-F-dC-3'-succinate, TEA salt; 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-3'-O-succinate-2'-fluoro-deoxycytidine, triethylamine salt; 5'-DMT-N4-Ac-2'-F-dC-3'-succinate, TEA salt; Triethylamine 4-(((2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl)oxy)-4-oxobutanoate

Related CAS: 2746380-45-8 (free base)

5'-O-DMT-3'-O-succinate-2'-F-deoxyuridine, triethylamine salt

Description: 5'-O-DMT-3'-O-succinate-2'-F-deoxyuridine, triethylamine salt is a modified deoxyuridine nucleoside. It features a 5'-dimethoxytrityl (DMT) group at the 5'-hydroxyl, a succinate ester at the 3'-hydroxyl, and a fluorine atom (2'-F) modification on the deoxyribose sugar. This compound, in its triethylamine salt form, enhances stability and enzymatic resistance in oligonucleotide synthesis, making it valuable for applications such as gene therapy and molecular diagnostics.

CAT: BRP-01575

CAS: 2294880-79-6

MF: C40H48FN3O10

MF: 749.82

Purity: ≥98% by HPLC

Appearance: White to yellow powder

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InChIKey: ZLUXDOSHTOAICW-GNGCXMSBSA-N

CanonicalSMILES: CCN(CC)CC.COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(C(C(O4)N5C=CC(=O)NC5=O)F)OC(=O)CCC(=O)O

IUPAC Name: 4-[(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-fluorooxolan-3-yl]oxy-4-oxobutanoic acid;N,N-diethylethanamine

InChI: InChI=1S/C34H33FN2O10.C6H15N/c1-43-24-12-8-22(9-13-24)34(21-6-4-3-5-7-21,23-10-14-25(44-2)15-11-23)45-20-26-31(47-29(41)17-16-28(39)40)30(35)32(46-26)37-19-18-27(38)36-33(37)42;1-4-7(5-2)6-3/h3-15,18-19,26,30-32H,16-17,20H2,1-2H3,(H,39,40)(H,36,38,42);4-6H2,1-3H3/t26-,30-,31-,32-;/m1./s1

Synonyms: DMT-2'-F-dU-3'-succinate, TEA salt; 5'-O-(4,4'-dimethoxytrityl)-3'-O-succinate-2'-fluoro-deoxyuridine, triethylamine salt; Triethylamine 4-(((2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl)oxy)-4-oxobutanoate; 5'-O-(4,4'-Dimethoxytrityl)-2'-fluoro-deoxyuridine 3'-O-succinate, triethylamine salt; 5'-DMT-2'-F-dU-3'-succinate, TEA salt

Related CAS: 2294880-67-2 (free base)

1-(2-Fluoro-2-deoxy-β-L-arabinofuranosyl)cytosine

Description: 1-(2-Fluoro-2-deoxy-β-L-arabinofuranosyl)cytosine is a modified nucleoside where cytosine is attached to a β-L-arabinofuranosyl sugar with a 2-fluoro-2-deoxy modification. This modification enhances the stability and alters the chemical properties of the nucleoside, making it useful in nucleic acid chemistry for applications such as nucleotide analog synthesis and structural studies.

CAT: BRP-01592

CAS: 163686-35-9

MF: C9H12FN3O4

MF: 245.21

Purity: ≥98%

Appearance: White to off-white powder

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Density: 1.82±0.1 g/cm3

Boiling Point: 500.1±60.0 °C at 760 mmHg

InChIKey: NVZFZMCNALTPBY-UCVXFZOQSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)F

IUPAC Name: 4-amino-1-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C9H12FN3O4/c10-6-7(15)4(3-14)17-8(6)13-2-1-5(11)12-9(13)16/h1-2,4,6-8,14-15H,3H2,(H2,11,12,16)/t4-,6+,7-,8-/m0/s1

Synonyms: 2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-; L-2'-F-Ara-Cytidine; 1-(2-Deoxy-2-fluoro-beta-L-arabinofuranosyl) cytosine; 4-amino-1-((2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 4-Amino-1-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-2(1H)-pyrimidinone

9-(2'-Fluoro-2'-deoxy-β-L-arabinofuranosyl)adenine

Description: 9-(2'-Fluoro-2'-deoxy-β-L-arabinofuranosyl)adenine is a modified nucleoside where adenine is attached to a β-L-arabinofuranosyl sugar with a 2'-fluoro-2'-deoxy modification at the ribose. This modification enhances the stability and alters the chemical properties of the nucleoside, making it useful in nucleic acid chemistry for applications such as nucleotide analog synthesis and structural studies.

CAT: BRP-01593

CAS: 193754-07-3

MF: C10H12FN5O3

MF: 269.23

Purity: ≥98%

Appearance: White to off-white powder

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Density: 2.01±0.1 g/cm3

Boiling Point: 628.6±65.0 °C at 760 mmHg

InChIKey: ZGYYPTJWJBEXBC-JZWIFLOVSA-N

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)F)N

IUPAC Name: (2S,3S,4R,5S)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol

InChI: InChI=1S/C10H12FN5O3/c11-5-7(18)4(1-17)19-10(5)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5+,7-,10-/m0/s1

Synonyms: L-2'-F-Ara-Adenosine; 9-(2-Deoxy-2-fluoro-beta-L-arabinofuranosyl)adenine; (2S,3S,4R,5S)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol; 9-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-9H-purin-6-amine; 9H-Purin-6-amine, 9-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-

9-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)guanine

Description: 9-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)guanine is a modified nucleoside where guanine is attached to a β-L-arabinofuranosyl sugar with a 2-deoxy-2-fluoro modification. This modification enhances the stability and alters the chemical properties of the nucleoside, making it useful in nucleic acid chemistry for applications such as nucleotide analog synthesis and structural studies.

CAT: BRP-01594

CAS: 193754-19-7

MF: C10H12FN5O4

MF: 285.23

Purity: ≥98%

Appearance: White to off-white powder

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Density: 2.17±0.1 g/cm3

Boiling Point: 726.1±70.0 °C at 760 mmHg

InChIKey: UXUZARPLRQRNNX-LSSUFRDISA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)F)N=C(NC2=O)N

IUPAC Name: 2-amino-9-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H12FN5O4/c11-4-6(18)3(1-17)20-9(4)16-2-13-5-7(16)14-10(12)15-8(5)19/h2-4,6,9,17-18H,1H2,(H3,12,14,15,19)/t3-,4+,6-,9-/m0/s1

Synonyms: L-2'-F-Ara-Guanosine; 9-(2-Fluoro-2-deoxy-β-L-arabinofuranosyl)guanine; 6H-Purin-6-one, 2-amino-9-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-3,9-dihydro-; 2-Amino-9-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-3,9-dihydro-6H-purin-6-one; 2-amino-9-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]purin-6-ol; 6H-Purin-6-one, 2-amino-9-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-1,9-dihydro-; 2-Amino-9-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-1,9-dihydro-6H-purin-6-one

1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)uracil

Description: 1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)uracil is a modified nucleoside where uracil is attached to a β-L-arabinofuranosyl sugar with a 2-deoxy-2-fluoro modification. This modification enhances the stability and alters the chemical properties of the nucleoside, making it useful in nucleic acid chemistry for applications such as nucleotide analog synthesis and structural studies.

CAT: BRP-01595

CAS: 1312300-54-1

MF: C9H11FN2O5

MF: 246.19

Purity: ≥98%

Appearance: White to off-white powder

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Density: 1.63±0.1 g/cm3

InChIKey: UIYWFOZZIZEEKJ-UCVXFZOQSA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)F

IUPAC Name: 1-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6+,7-,8-/m0/s1

Synonyms: 1-((2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-Deoxy-2'-fluoro-beta-L-arabinouridine; 1-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-; 2'-Fluoro-5-ethyl-1-β-L-arabinofuranosyluracil

N,2'-O,3'-O-Triacetylcytidine

Description: N,2'-O,3'-O-Triacetylcytidine is an exceptional biomedical product, used for studying conspicuous viral infections, such as hepatitis C and influenza. It has the remarkable ability to impede viral RNA replication.

CAT: BRP-01628

CAS: 40632-06-2

MF: C15H19N3O8

MF: 369.33

Appearance: White to off-white powder

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Storage: Store at -20 °C

Density: 1.53±0.1 g/cm3

InChIKey: PWCGIZSEUGLASX-FMKGYKFTSA-N

CanonicalSMILES: CC(=O)NC1=NC(=O)N(C=C1)C2C(C(C(O2)CO)OC(=O)C)OC(=O)C

IUPAC Name: [(2R,3R,4R,5R)-5-(4-acetamido-2-oxopyrimidin-1-yl)-4-acetyloxy-2-(hydroxymethyl)oxolan-3-yl] acetate

InChI: InChI=1S/C15H19N3O8/c1-7(20)16-11-4-5-18(15(23)17-11)14-13(25-9(3)22)12(24-8(2)21)10(6-19)26-14/h4-5,10,12-14,19H,6H2,1-3H3,(H,16,17,20,23)/t10-,12-,13-,14-/m1/s1

Synonyms: N4-acetyl-2',3'-diacetyl-cytidine; 2',3'-diAc-C(Ac); Cytidine, N-acetyl-, 2',3'-diacetate; (2R,3R,4R,5R)-2-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl diacetate; N-Acetyl-2',3'-di-O-acetylcytidine

5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O,4'-C-methyleneguanosine

Description: 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O,4'-C-methyleneguanosine is a revolutionary biomedical substance renowned for its remarkable antiviral and antiproliferative attributes.

CAT: BRP-01629

CAS: 206055-72-3

MF: C36H37N5O8

MF: 667.71

Purity: ≥95%

Appearance: Off-white to yellow powder

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Storage: Store at -20 °C

Density: 1.41±0.1 g/cm3

InChIKey: JMGQUFRCVHVMAX-UBMDZZGASA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C4C(C(O3)(CO4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O

IUPAC Name: N-[9-[(1R,3R,4R,7S)-1-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C36H37N5O8/c1-21(2)31(43)39-34-38-30-27(32(44)40-34)37-20-41(30)33-28-29(42)35(49-33,18-47-28)19-48-36(22-8-6-5-7-9-22,23-10-14-25(45-3)15-11-23)24-12-16-26(46-4)17-13-24/h5-17,20-21,28-29,33,42H,18-19H2,1-4H3,(H2,38,39,40,43,44)/t28-,29+,33-,35-/m1/s1

Synonyms: N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-guanosine; N2-iBu-DMT-2'-O-4'-C-Locked-Gr; N-(9-{(1R,3R,4R,7S)-1-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-7-hydroxy-2,5-dioxa-bicyclo[2.2.1]hept-3-yl}-6-oxo-6,9-dihydro-1H-purin-2-yl)-isobutyramide; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O,4'-C-methylene-N-(2-methyl-1-oxopropyl)-; (1R,3R,4R,7S)-1-(4,4'-Dimethoxytrityloxymethyl)-7-hydroxy-3-(2-N-isobutyrylguanin-9-yl)-2,5-dioxabicyclo[2.2.1]heptane

N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-2'-O,4'-C-methylenecytidine

Description: N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-2'-O,4'-C-methylenecytidine, a highly potent compound extensively employed in the biomedical field, exhibits exceptional efficacy in combatting viral infections. This compound particularly exhibits remarkable proficiency against RNA viruses, such as SARS-CoV-2, ensuring its pervasive usefulness. By engaging viral RNA polymerase, it effectively impedes viral replication, thereby portraying its indispensable antiviral attributes.

CAT: BRP-01630

CAS: 445012-77-1

MF: C39H37N3O8

MF: 675.73

Purity: ≥98% by HPLC

Appearance: White, off-white to faint yellow powder

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Storage: Store at 2-8 °C, in tightly closed container, protected from light and humidity

Density: 1.32±0.1 g/cm3

InChIKey: CTGWFRQUULNNIN-OSZGUBSQSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C4C(C(O3)(CO4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O

IUPAC Name: N-(1-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide

InChI: InChI=1S/C39H37N3O8/c1-25-22-42(37(45)41-34(25)40-35(44)26-10-6-4-7-11-26)36-32-33(43)38(50-36,23-48-32)24-49-39(27-12-8-5-9-13-27,28-14-18-30(46-2)19-15-28)29-16-20-31(47-3)21-17-29/h4-22,32-33,36,43H,23-24H2,1-3H3,(H,40,41,44,45)/t32-,33+,36-,38-/m1/s1

Synonyms: N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-4'-C-Locked-5-methyl-cytidine; N-(1-((1R,3R,4R,7S)-1-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide; Benzamide, N-[1-[2,5-anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-α-L-lyxofuranosyl]-1,2-dihydro-5-methyl-2-oxo-4-pyrimidinyl]-; N-[1-[2,5-Anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-α-L-lyxofuranosyl]-1,2-dihydro-5-methyl-2-oxo-4-pyrimidinyl]benzamide; N4-Bz-DMT-2'-O-4'-C-Locked-5-Me-Cr

N4-Benzoyl-5'-O-(dimethoxytrityl)-5-methyl-2'-O-methylcytidine

Description: N4-Benzoyl-5'-O-(dimethoxytrityl)-5-methyl-2'-O-methylcytidine, a recently developed cytidine derivative, exhibits potential application in treating various diseases, such as cancer and viral infections, by suppressing malignancy and viral proliferation whilst preserving normal cells. With its unique mechanism, this product may have a significant impact in the combat of severe afflictions.

CAT: BRP-01631

CAS: 741725-57-5

MF: C39H39N3O8

MF: 677.76

Purity: ≥98% by HPLC

Appearance: White, off-white to faint yellow powder

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Storage: Store at 2-8 °C, Keep in a dark and dry place

Density: 1.26±0.1 g/cm3 (Predicted)

InChIKey: BUUDDUQHVVDKLA-TUDCZORBSA-N

CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OC

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C39H39N3O8/c1-25-23-42(38(45)41-35(25)40-36(44)26-11-7-5-8-12-26)37-34(48-4)33(43)32(50-37)24-49-39(27-13-9-6-10-14-27,28-15-19-30(46-2)20-16-28)29-17-21-31(47-3)22-18-29/h5-23,32-34,37,43H,24H2,1-4H3,(H,40,41,44,45)/t32-,33-,34-,37-/m1/s1

Synonyms: N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-5-methyl-Cytidine; DMT-2'-O-Me-5-Me-C(Bz); 5'-O-DMT-2'-OMe-N4-Bz-5-Me-C; N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine; 5'-O-(4,4'-Dimethoxytrityl)-N4-Benzoyl-2'-O-Methy-5-MethyCytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-5-methyl-2'-O-methylcytidine; N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine

5'-O-DMT-2'-O-methylcytidine

Description: 5'-O-DMT-2'-O-methylcytidine is a biomedicine research product used for the treatment of viral infections, cancer, and neurological disorders. It acts as an antiviral and anticancer agent by inhibiting viral replication and tumor growth, respectively. Additionally, it also has neuroprotective properties that help in treating neurological disorders.

CAT: BRP-01632

CAS: 103285-21-8

MF: C31H33N3O7

MF: 559.62

Purity: ≥98% by HPLC

Appearance: White to Off-white Powder

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Storage: Store at 2-8°C

Density: 1.3±0.1 g/cm3

Boiling Point: 729.7±70.0°C at 760 mmHg

InChIKey: JUECLTUXFCGWTO-YXINZVNLSA-N

CanonicalSMILES: COC1C(C(OC1N2C=CC(=NC2=O)N)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C31H33N3O7/c1-37-23-13-9-21(10-14-23)31(20-7-5-4-6-8-20,22-11-15-24(38-2)16-12-22)40-19-25-27(35)28(39-3)29(41-25)34-18-17-26(32)33-30(34)36/h4-18,25,27-29,35H,19H2,1-3H3,(H2,32,33,36)/t25-,27-,28-,29-/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine; DMT-2'-OMe-Cr; 5'-O-DMT-2'-O-methyl-D-cytidine; 5'-O-DMT-2'-OMe-rC; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylcytidine

5'-O-(Dimethoxytrityl)-2'-O-methylinosine

Description: 5'-O-(Dimethoxytrityl)-2'-O-methylinosine is an indispensable compound employed in the biomedical industry, showcasing considerable promise as a research tool for diverse afflictions and maladies. With profound implications in drug development, it enables the precise modulation of molecular pathways and gene expressions. The multifaceted utilization of this compound extends to the realm of research of cancer, viral infections and neurological impairments.

CAT: BRP-01633

CAS: 128219-84-1

MF: C32H32N4O7

MF: 584.63

Purity: ≥97% by HPLC

Appearance: White to off-white powder

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Storage: Store at 2-8 °C, Keep in a dark and dry place

Density: 1.35±0.1 g/cm3

Boiling Point: 841.8±65.0 °C at 760 mmHg

InChIKey: KXFBGUCGEWPHRA-QWOIFIOOSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=CNC3=O)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: 9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C32H32N4O7/c1-39-23-13-9-21(10-14-23)32(20-7-5-4-6-8-20,22-11-15-24(40-2)16-12-22)42-17-25-27(37)28(41-3)31(43-25)36-19-35-26-29(36)33-18-34-30(26)38/h4-16,18-19,25,27-28,31,37H,17H2,1-3H3,(H,33,34,38)/t25-,27-,28-,31-/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-inosine; DMT-2'-OMe-Ir; 5'-O-Dmt-2'-O-methyl-inosine; Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-; 9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-methoxytetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one

5'-O-DMT-2'-O-methylguanosine

Description: 5'-O-DMT-2'-O-methylguanosine, a nucleoside analogue, finds its purpose in biomedical research due to its potential antiviral activity against RNA viruses, an area of significant scientific interest. Its inhibitory role in the replication of notorious viruses such as Zika virus and hepatitis C virus warrants further academic study.

CAT: BRP-01634

CAS: 103285-24-1

MF: C32H33N5O7

MF: 599.65

Purity: ≥98% by HPLC

Appearance: White to off-white powder

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Density: 1.40±0.1 g/cm3

InChIKey: AYVWAUNZRMANQB-BQOYKFDPSA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=C2N=C(NC3=O)N)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C32H33N5O7/c1-40-22-13-9-20(10-14-22)32(19-7-5-4-6-8-19,21-11-15-23(41-2)16-12-21)43-17-24-26(38)27(42-3)30(44-24)37-18-34-25-28(37)35-31(33)36-29(25)39/h4-16,18,24,26-27,30,38H,17H2,1-3H3,(H3,33,35,36,39)/t24-,26-,27-,30-/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-guanosine; DMT-2'-OMe-Gr; 2'-O-Methyl-5'-O-DMT-D-guanosine; 5'-O-Dimethoxytrityl-2'-O-methylguanosine; 5'-O-DMT-2'-O-methyl-D-guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methylguanosine

3'-O-Acetyl-5'-O-DMT-5-iodo-2'-O-methyl-uridine

Description: Highly specialized in the field of biomedicine, 3'-O-Acetyl-5'-O-DMT-5-iodo-2'-O-methyl-uridine stands as a critical compound. Its employment primarily revolves around synthesizing nucleotide analogs for antiviral drug development and acting as a probe in biochemical studies concerning RNA. Promising therapeutic applications against viral infections, like HIV and hepatitis B, are attributed to this product.

CAT: BRP-01635

CAS: 1374692-34-8

MF: C33H33IN2O9

MF: 728.53

Purity: ≥95%

Appearance: White Solid

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Density: 1.55±0.1 g/cm3

InChIKey: FRHDXHYTYBOQIT-BUVRPPHQSA-N

CanonicalSMILES: CC(=O)OC1C(OC(C1OC)N2C=C(C(=O)NC2=O)I)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC

IUPAC Name: [(2R,3R,4R,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(5-iodo-2,4-dioxopyrimidin-1-yl)-4-methoxyoxolan-3-yl] acetate

InChI: InChI=1S/C33H33IN2O9/c1-20(37)44-28-27(45-31(29(28)42-4)36-18-26(34)30(38)35-32(36)39)19-43-33(21-8-6-5-7-9-21,22-10-14-24(40-2)15-11-22)23-12-16-25(41-3)17-13-23/h5-18,27-29,31H,19H2,1-4H3,(H,35,38,39)/t27-,28-,29-,31-/m1/s1

Synonyms: 5'-O-(4,4'-dimethoxytrityl)-3'-acetyl-5-Iodo-2'-O-methyl-uridine; 5'-O-DMT-3'-Ac-5-I-2'-OMe-Ur; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-3'-O-acetyl-5-iodouridine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-5-iodo-2'-O-methyl-uridine 3'-acetate; 5-Iodo-5'-DMT-2'-O-methyl-3'-acetyl-uridine; 3'-O-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-5-iodo-2'-O-methyluridine

5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine

Description: 5'-O-DMT-N2-isobutyryl-2'-O-propargylguanosine is an advanced compound prescribed for research of viral infections, demonstrating inhibitory efficacy by selectively targeting specific RNA viruses. Employing a potent mechanism of inhibiting viral replication and considerably attenuating viral loads, this compound exhibits promising potential in the research of RNA virus-induced ailments such as influenza and hepatitis C.

CAT: BRP-01636

CAS: 171486-53-6

MF: C38H39N5O8

MF: 693.74

Purity: ≥95%

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Density: 1.31±0.1 g/cm3

InChIKey: ZTBYTNLGRCUAEU-BEGXHNNXSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OCC#C

IUPAC Name: N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-prop-2-ynoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide

InChI: InChI=1S/C38H39N5O8/c1-6-20-49-32-31(44)29(51-36(32)43-22-39-30-33(43)40-37(42-35(30)46)41-34(45)23(2)3)21-50-38(24-10-8-7-9-11-24,25-12-16-27(47-4)17-13-25)26-14-18-28(48-5)19-15-26/h1,7-19,22-23,29,31-32,36,44H,20-21H2,2-5H3,(H2,40,41,42,45,46)/t29-,31-,32-,36-/m1/s1

Synonyms: N2-iBu-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl-guanosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-2-propyn-1-yl-Guanosine; N2-iBu-DMT-2'-O-propargyl-Gr; N2-iso-Butyroyl-5'-(4,4'-dimethoxytrityl)-2'-O-propargylguanosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-N-isobutyryl-2'-O-2-propyn-1-ylguanosine; Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-2'-O-2-propynyl-