Nucleosides - RNA / BOC Sciences

2-Thiouridine

Description: 2-Thiouridine, an esteemed biomedical marvel, is renowned for its profound efficacy in combatting malignant neoplasms and thwarting viral affections. This exalted nucleoside derivative ingeniously integrates itself into RNA, instigating the impeding of viral propagation and invoking apoptosis within neoplastic entities. Its exceptional anti-tumorigenic and antiviral prowess has propelled 2-Thiouridine to the vanguard of biomedical exploration and therapeutic breakthroughs.

CAT: BRP-01780

CAS: 20235-78-3

MF: C9H12N2O5S

MF: 260.27

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at 2-8°C under inert atmosphere

Density: 1.72±0.1 g/cm3 at 20°C, 760 Torr

Melting Point: 216-218 °C

Symbol: s²U

InChIKey: GJTBSTBJLVYKAU-XVFCMESISA-N

Solubility: Soluble in DMSO (Slightly, Heated), Water (Slightly, Heated)

CanonicalSMILES: C1=CN(C(=S)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one

InChI: InChI=1S/C9H12N2O5S/c12-3-4-6(14)7(15)8(16-4)11-2-1-5(13)10-9(11)17/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,17)/t4-,6-,7-,8-/m1/s1

Synonyms: 1-β-D-Ribofuranosyl-2-thiouracil; 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; Thiouridine

2-Amino-6-chloropurine-9-(2'-O-propargyl)riboside

Description: 2-Amino-6-chloropurine-9-(2'-O-propargyl)riboside, a revolutionary biomedicine, has been developed to combat various types of malignant tumors. This potent compound, an incredibly effective CDK9 inhibitory agent, promises to be a boon in the scientific community as it is capable of arresting malignant cell division and growth. Studies have shown that this complex could potentially mitigate the adverse effects of leukemia, lymphoma, and breast cancer, making it a versatile cure for widespread ailments. Furthermore, in addition to its medicinal properties, its potential application as a research tool in understanding CDK9 mediated phenomenon in cellular processes is also noteworthy.

CAT: BRP-01781

CAS: 2095417-35-7

MF: C13H14ClN5O4

MF: 339.73

Purity: ≥95%

Appearance: White to off-white solid

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Storage: Store at 2-8 °C

Density: 1.75±0.1 g/cm3

Boiling Point: 704.4±70.0 °C at 760 mmHg

InChIKey: QAXQMTXPZDSDLF-WOUKDFQISA-N

CanonicalSMILES: C#CCOC1C(C(OC1N2C=NC3=C2N=C(N=C3Cl)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(2-amino-6-chloropurin-9-yl)-2-(hydroxymethyl)-4-prop-2-ynoxyoxolan-3-ol

InChI: InChI=1S/C13H14ClN5O4/c1-2-3-22-9-8(21)6(4-20)23-12(9)19-5-16-7-10(14)17-13(15)18-11(7)19/h1,5-6,8-9,12,20-21H,3-4H2,(H2,15,17,18)/t6-,8-,9-,12-/m1/s1

Synonyms: 2-Amino-6-chloro-9-(2-O-propargyl-b-D-ribofuranosyl)-9H-purine; 2-Amino-6-chloro-2'-O-propargylpurine-9-riboside; 2-Amino-6-chloro-9-(2'-O-propargyl-b-D-ribofuranosyl)purine; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-ol

6-Azauridine

Description: 6-Azauridine is a nucleoside analog where a nitrogen atom replaces the carbon at the sixth position of the uridine base, altering its chemical properties and inhibiting RNA and DNA synthesis. It is studied for its antiviral and anticancer potential due to its ability to interfere with nucleic acid metabolism. Additionally, 6-azauridine is used in biochemical research to explore the effects of nucleoside analogs on cellular processes and enzyme activities related to nucleic acid synthesis.

CAT: BRP-01782

CAS: 54-25-1

MF: C8H11N3O6

MF: 245.19

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at 2-8°C under inert atmosphere

Density: 2.08±0.1 g/cm3

Melting Point: >238°C (dec.)

InChIKey: WYXSYVWAUAUWLD-SHUUEZRQSA-N

Solubility: Soluble in DMSO (Slightly, Heated), Methanol (Slightly, Heated), Pyridine (Slightly), Water

CanonicalSMILES: C1=NN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazine-3,5-dione

InChI: InChI=1S/C8H11N3O6/c12-2-3-5(14)6(15)7(17-3)11-8(16)10-4(13)1-9-11/h1,3,5-7,12,14-15H,2H2,(H,10,13,16)/t3-,5-,6-,7-/m1/s1

Synonyms: 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione; 2-β-D-Ribofuranosyl-as-triazine-3,5(2H,4H)-dione; 6-AzUr; 6-Azauracil 1-riboside; 6-Azauracil-β-D-riboside; NSC 32074; Ribo-azuracil; Riboazauracil; Azauridine

9-(b-D-Xylofuranosyl)adenine

Description: 9-(b-D-Xylofuranosyl)adenine is an anticancer agent. 9-(β-D-Xylofuranosyl)adenine is a nucleoside analog in which the ribose sugar of adenosine is replaced with β-D-xylofuranose, altering its interaction with nucleic acid-related enzymes. It is used in biochemical research to study the effects of sugar modifications on nucleoside function and enzyme activity. Additionally, it has potential applications in antiviral and anticancer research due to its ability to disrupt nucleic acid synthesis and function.

CAT: BRP-01784

CAS: 524-69-6

MF: C10H13N5O4

MF: 267.24

Purity: ≥95%

Appearance: White solid

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Storage: Store at 2-8 °C

Density: 2.08±0.1 g/cm3 (Predicted)

Melting Point: 125-140°C

Boiling Point: 676.3±65.0°C (Predicted)

InChIKey: OIRDTQYFTABQOQ-GAWUUDPSSA-N

Solubility: Soluble in DMF, DMSO, Methanol, Water

CanonicalSMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N

IUPAC Name: (2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6+,7-,10-/m1/s1

Synonyms: Xylo-adenosine; NSC7359; 9-β-D-Xylofuranosyladenine; NSC 7359; (2R,3R,4R,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Adenine xyloside; Xylosyladenine; Xylosyl A; 9-β-D-Xylofuranosyl-9H-purin-6-amine; Adenine, 9-β-D-xylofuranosyl-; Adenine β-D-xylofuranoside; Adenine-9-β-D-xylofuranoside; AMG 002370; NQZ-007; NSC 7359; Xyloadenosine

5-Aminouridine

Description: 5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. It therefore exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses.

CAT: BRP-01785

CAS: 2149-76-0

MF: C9H13N3O6

MF: 259.22

Purity: ≥95%

Appearance: Off-white to Yellow Powder

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Storage: Store at -20°C

Density: 1.712±0.06 g/cm3 (Predicted)

Melting Point: 214-216°C

InChIKey: YBTWWWIJBCCYNR-UAKXSSHOSA-N

Solubility: Soluble in Methanol (Slightly, Heated), Water (Slightly, Sonicated)

CanonicalSMILES: C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)O)N

IUPAC Name: 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H13N3O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2,10H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1

Synonyms: 5-Amino Uridine; 5-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5-Amino-1-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione; NSC 72560

Related CAS: 116154-74-6 (monohydrochloride)

Kinetin Riboside

Description: Kinetin Riboside is a cell growth inhibitor used as an anticancer and antiviral agent. Kinetin Riboside is a modified nucleoside where a furfuryl group is attached to the sixth position nitrogen of the adenosine base. This modification is utilized in biochemical research to investigate nucleic acid structure and function, RNA modification studies, and drug development due to its potential to modulate nucleic acid metabolism. Its altered chemical properties make it a valuable tool for understanding RNA biology and exploring therapeutic applications.

CAT: BRP-01786

CAS: 4338-47-0

MF: C15H17N5O5

MF: 347.33

Purity: ≥95%

Appearance: White to Pale Brown Solid

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Storage: Store at -20°C under inert atmosphere

Density: 1.78±0.1 g/cm3

Melting Point: >129°C (dec.)

Boiling Point: 683.7±65.0°C at 760 mmHg

InChIKey: CAGLGYNQQSIUGX-SDBHATRESA-N

Solubility: Soluble in DMSO (Slightly), Ethanol (Slightly, Heated, Sonicated), Methanol (Very Slightly)

CanonicalSMILES: C1=COC(=C1)CNC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O

IUPAC Name: (2R,3R,4S,5R)-2-[6-(furan-2-ylmethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C15H17N5O5/c21-5-9-11(22)12(23)15(25-9)20-7-19-10-13(17-6-18-14(10)20)16-4-8-2-1-3-24-8/h1-3,6-7,9,11-12,15,21-23H,4-5H2,(H,16,17,18)/t9-,11-,12-,15-/m1/s1

Synonyms: Furfurylaminopurineriboside; N6-Furfuryladenosine; 6-Furfurylaminopurine Riboside, N-(2-Furanylmethyl)adenosine; NSC 120958; Ribosylkinetin; Kinetin-9-riboside; N6-(2-Furanyl-methyl)adenosine; N-(2-Furylmethyl)-9-pentofuranosyl-9H-purin-6-amine

3-Deazauridine

Description: 3-Deazauridine is a nucleoside analog. It is converted intracellularly to 3-deazauridine triphosphate, which competitively inhibits cytidine triphosphate synthetase thereby inhibiting biosynthesis of the nucleic acid cytidine 5'-triphosphate (CTP).

CAT: BRP-01787

CAS: 23205-42-7

MF: C10H13NO6

MF: 243.21

Purity: ≥95%

Appearance: White to Pale Beige Solid

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Storage: Store at 2-8°C

Density: 1.718±0.06 g/cm3 (Predicted)

Melting Point: 230-232 °C

Boiling Point: 569.2±50.0°C (Predicted)

Application: Antimetabolites, Antineoplastic

InChIKey: CBOKZNLSFMZJJA-PEBGCTIMSA-N

Solubility: Soluble in DMF (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=CN(C(=O)C=C1O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxypyridin-2-one

InChI: InChI=1S/C10H13NO6/c12-4-6-8(15)9(16)10(17-6)11-2-1-5(13)3-7(11)14/h1-3,6,8-10,12-13,15-16H,4H2/t6-,8-,9-,10-/m1/s1

Synonyms: 4-Hydroxy-1-beta-D-ribofuranosyl-2(1H)-pyridinone; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxypyridin-2(1H)-one; 1-β-D-Ribofuranosyl-4-hydroxy-2-pyridone; 4-Hydroxy-1-(β-D-ribofuranosyl)-2-pyridone; NSC 126849

(R)-N-(2,3-dihydro-1H-indenyl)adenosine

Description: PD-117519 is a N6-substituted adenosine receptor agonist. It shows oral antihypertensive activity in pharmacological animal models. It is used as a potential antihypertensive agent.

CAT: BRP-01789

CAS: 96392-15-3

MF: C19H21N5O4

MF: 383.40

Purity: ≥95%

Appearance: White solid

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Storage: Store at -20°C

Density: 1.71±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr

Melting Point: 185-187 °C

Boiling Point: 723.3±70.0 °C | Condition: Press: 760 Torr

Application: PD-117519 is used as a potential antihypertensive agent.

Shelf Life: 2 month in rt, long time

InChIKey: FSKMJUWPFLDDRS-BYMDKACISA-N

Solubility: Soluble in DMSO (>3.9 mg/mL)

CanonicalSMILES: C1CC2=CC=CC=C2C1NC3=NC=NC4=C3N=CN4C5C(C(C(O5)CO)O)O

IUPAC Name: (2R,3R,4S,5R)-2-[6-[[(1R)-2,3-dihydro-1H-inden-1-yl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C19H21N5O4/c25-7-13-15(26)16(27)19(28-13)24-9-22-14-17(20-8-21-18(14)24)23-12-6-5-10-3-1-2-4-11(10)12/h1-4,8-9,12-13,15-16,19,25-27H,5-7H2,(H,20,21,23)/t12-,13-,15-,16-,19-/m1/s1

Synonyms: N-[(R)-Indan-1-yl]adenosine; PD 117519; PD117519; PD-117519; N-[(1R)-2,3-Dihydro-1H-inden-1-yl]adenosine; N-[[(R)-2,3-Dihydro-1H-inden]-1α-yl]adenosine; (2R,3R,4S,5R)-2-(6-(((R)-2,3-dihydro-1H-inden-1-yl)amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; CI-947; CI 947; CI 947

1-Methylinosine

Description: 1-Methylinosine is a modified nucleoside which is present in higher concentrations in the urinary excretion of patients afflicted with breast cancer. It acts as a biomarker for diagnosis of the disease.

CAT: BRP-01790

CAS: 2140-73-0

MF: C11H14N4O5

MF: 282.26

Purity: ≥95%

Appearance: White Solid

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Storage: Store at -20°C

Density: 1.88±0.1 g/cm3 (Predicted)

Melting Point: 211-212 °C

Boiling Point: 695.3±65.0 °C at 760 mmHg

Symbol: m¹I

InChIKey: WJNGQIYEQLPJMN-IOSLPCCCSA-N

Solubility: Soluble in Chloroform (Slightly, Heated), DMSO (Slightly, Heated)

CanonicalSMILES: CN1C=NC2=C(C1=O)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpurin-6-one

InChI: InChI=1S/C11H14N4O5/c1-14-3-13-9-6(10(14)19)12-4-15(9)11-8(18)7(17)5(2-16)20-11/h3-5,7-8,11,16-18H,2H2,1H3/t5-,7-,8-,11-/m1/s1

Synonyms: N1-Methylinosine; 1-Methyl-Inosine; Inosine, 1-methyl-; 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1-methyl-1,9-dihydro-6H-purin-6-one

3'-O-Propargyladenosine

Description: 3'-O-Propargyladenosine, a pharmaceutical product extensively employed within the biomedical industry, exhibits remarkable efficacy in treating numerous ailments, inclusive of cancer and viral infections. Via its potent antineoplastic properties, it diligently impedes the proliferation of malignant tumors, while commendably repressing viral replication as an antiviral agent.

CAT: BRP-01791

CAS: 2305416-10-6

MF: C13H15N5O4

MF: 305.29

Purity: ≥97% by HPLC

Appearance: White to off-white solid

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Storage: Store at 2-8 °C

Density: 1.7±0.1 g/cm3

Boiling Point: 655.1±65.0°C at 760 mmHg

InChIKey: SLZDQTVTJDVDJE-QYVSTXNMSA-N

CanonicalSMILES: C#CCOC1C(OC(C1O)N2C=NC3=C(N=CN=C32)N)CO

IUPAC Name: (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)-4-prop-2-ynoxyoxolan-3-ol

InChI: InChI=1S/C13H15N5O4/c1-2-3-21-10-7(4-19)22-13(9(10)20)18-6-17-8-11(14)15-5-16-12(8)18/h1,5-7,9-10,13,19-20H,3-4H2,(H2,14,15,16)/t7-,9-,10-,13-/m1/s1

Synonyms: 3'-(O-propargyl) Adenosine; 3'-O-2-Propyn-1-yladenosine; 3'-O-Propargyl-D-adenosine; (2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxymethyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-ol

2'-O-(2-Methoxyethyl)-2-aminoadenosine

Description: 2'-O-(2-Methoxyethyl)-2-aminoadenosine is a vital compound widely used in the biomedical industry. It exhibits potent antiviral properties, making it a valuable tool in the treatment and research of viral infections such as HIV.

CAT: BRP-01793

CAS: 256224-13-2

MF: C13H20N6O5

MF: 340.34

Purity: ≥95%

Appearance: White to off-white solid

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Storage: Store at 2-8 °C

Density: 1.81±0.1 g/cm3

Boiling Point: 734.5±70.0°C at 760 mmHg

InChIKey: ZPWSGIIALWUBNX-WOUKDFQISA-N

CanonicalSMILES: COCCOC1C(C(OC1N2C=NC3=C(N=C(N=C32)N)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(2,6-diaminopurin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)oxolan-3-ol

InChI: InChI=1S/C13H20N6O5/c1-22-2-3-23-9-8(21)6(4-20)24-12(9)19-5-16-7-10(14)17-13(15)18-11(7)19/h5-6,8-9,12,20-21H,2-4H2,1H3,(H4,14,15,17,18)/t6-,8-,9-,12-/m1/s1

Synonyms: Adenosine, 2-amino-2'-O-(2-methoxyethyl)-; 2-Amino-2'-O-(2-methoxyethyl)adenosine; (2R,3R,4R,5R)-5-(2,6-Diamino-9H-purin-9-yl)-2-(hydroxymethyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-ol; 9-[2-O-(2-Methoxyethyl)-β-D-xylofuranosyl]-9H-purine-2,6-diamine

1-Methylguanosine

Description: 1-Methylguanosine is a methylated nucleoside. It is known that some modified, especially methylated, nucleosides originating from RNA degradation are excreted in abnormal levels in the urine of patients with malignant tumours. These nucleosides have been proposed as tumour markers. Their measurement could provide a non-invasive diagnostic method, help identify different cancers, and monitor any therapeutic effects.

CAT: BRP-01794

CAS: 2140-65-0

MF: C11H15N5O5

MF: 297.27

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at -20°C under inert atmosphere

Density: 2.02±0.1 g/cm3 (Predicted)

Melting Point: 163 °C

Boiling Point: 737.4±70.0 °C at 760 mmHg

Symbol: m¹G

InChIKey: UTAIYTHAJQNQDW-KQYNXXCUSA-N

Solubility: Soluble in Methanol (Slightly), Water (Slightly)

CanonicalSMILES: CN1C(=O)C2=C(N=C1N)N(C=N2)C3C(C(C(O3)CO)O)O

IUPAC Name: 2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpurin-6-one

InChI: InChI=1S/C11H15N5O5/c1-15-9(20)5-8(14-11(15)12)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14)/t4-,6-,7-,10-/m1/s1

Synonyms: N1-Methylguanosine; Guanosine, 1-methyl-; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1-methyl-1H-purin-6(9H)-one; 1-Methyl-2-amino-9-(β-D-ribofuranosyl)-9H-purine-6(1H)-one; NSC 70897

8-Chloroadenosine

Description: 8-Chloroadenosine is an analog of adenosine. It is metabolized in vivo to 8-Chloro-ATP. It depletes ATP and inhibits tumor growth in hematological malignancies. It also inhibits tumor growth in lung and breast cancer cell lines. It incorporates into RNA during transcription and inhibits RNA synthesis. It mitotics catastrophe and induces G2/M cell cycle arrest in A549 and H1299 cells.
It is a useful research chemical and has cytotoxicity effects.

CAT: BRP-01796

CAS: 34408-14-5

MF: C10H12ClN5O4

MF: 301.69

Purity: ≥98% by HPLC

Appearance: White to Off-white Crystalline Powder

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Storage: Store at -20°C

Density: 2.19±0.1 g/cm3

Melting Point: 189-191 °C

Boiling Point: 707.4±70.0°C at 760 mmHg

InChIKey: MHDPPLULTMGBSI-UUOKFMHZSA-N

Solubility: Soluble in DMSO, Water

CanonicalSMILES: C1=NC(=C2C(=N1)N(C(=N2)Cl)C3C(C(C(O3)CO)O)O)N

IUPAC Name: (2R,3R,4S,5R)-2-(6-amino-8-chloropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C10H12ClN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)/t3-,5-,6-,9-/m1/s1

Synonyms: 6-Amino-8-chloropurine riboside; 8-Cl-Ado; 8-Chloro-adenosine; (2R,3R,4S,5R)-2-(6-amino-8-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Chloro-D-adenosine

6-Methoxy-9-(2-C-methyl-beta-D-ribofuranosyl)purine

Description: 6-Methoxy-9-(2-C-methyl-beta-D-ribofuranosyl)purine is a potent antiviral compound used in the research of viral infections, particularly those caused by herpes viruses. It exhibits a high selectivity index and low toxicity towards host cells, making it an effective option for suppressing viral replication. This nucleoside analogue inhibits the viral DNA polymerase, thus preventing viral DNA research and development and subsequent viral replication.

CAT: BRP-01797

CAS: 565450-78-4

MF: C12H16N4O5

MF: 296.28

Purity: ≥95%

Appearance: White foam solid

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Storage: Store at 2-8 °C

Density: 1.70±0.1 g/cm3 (Predicted)

Boiling Point: 588.7±60.0°C (Predicted)

InChIKey: HFOYSXHOPVYGPB-YUTYNTIBSA-N

CanonicalSMILES: CC1(C(C(OC1N2C=NC3=C2N=CN=C3OC)CO)O)O

IUPAC Name: (2R,3R,4R,5R)-5-(hydroxymethyl)-2-(6-methoxypurin-9-yl)-3-methyloxolane-3,4-diol

InChI: InChI=1S/C12H16N4O5/c1-12(19)8(18)6(3-17)21-11(12)16-5-15-7-9(16)13-4-14-10(7)20-2/h4-6,8,11,17-19H,3H2,1-2H3/t6-,8-,11-,12-/m1/s1

Synonyms: (2R,3R,4R,5R)-5-(hydroxymethyl)-2-(6-methoxy-9H-purin-9-yl)-3-methyltetrahydrofuran-3,4-diol; 2'-C-Methyl-6-O-methylinosine; Inosine, 2'-C-methyl-6-O-methyl-; 9H-Purine, 6-methoxy-9-(2-C-methyl-β-D-ribofuranosyl)-

N2-iBu-2',3'-bis-O-TBDMS guanosine

Description: N2-iBu-2',3'-bis-O-TBDMS guanosine is a highly esteemed compound within the biomedical sector, manifesting remarkable utility in studying diverse afflictions including viral infections, cancers and neurological disorders.

CAT: BRP-01798

CAS: 79974-70-2

MF: C26H47N5O6Si2

MF: 581.85

Purity: ≥95%

Appearance: White to off-white foam solid

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Storage: Store at 2-8 °C

Density: 1.20±0.1 g/cm3 (Predicted)

Melting Point: 149-150 °C

InChIKey: VZMILHMVPGBTBQ-DYVMYPEFSA-N

Solubility: Soluble in Methanol

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C

IUPAC Name: N-(9-((2R,3R,4R,5R)-3,4-bis((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

InChI: InChI=1S/C26H47N5O6Si2/c1-15(2)21(33)29-24-28-20-17(22(34)30-24)27-14-31(20)23-19(37-39(11,12)26(6,7)8)18(16(13-32)35-23)36-38(9,10)25(3,4)5/h14-16,18-19,23,32H,13H2,1-12H3,(H2,28,29,30,33,34)/t16-,18-,19-,23-/m1/s1

Synonyms: Guanosine, 2',3'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-; 2',3'-Bis-O-(tert-butyldimethylsilyl)-N2-isobutyroylguanosine

2',3'-Bis-(O-t-butyldimethylsilyl)uridine

Description: 2',3'-Bis-(O-t-butyldimethylsilyl)uridine, a widely utilized compound in the realm of biomedicine, assumes an indispensable function in the amalgamation of nucleoside analogs and antiviral pharmaceuticals, notably AZT and acyclovir. Moreover, it exerts an inhibitory effect on viral replication, rendering it instrumental in combating illnesses such as HIV and herpes. Its exceptional attributes render this biomedical research and drug development tool truly invaluable.

CAT: BRP-01800

CAS: 69504-12-7

MF: C21H40N2O6Si2

MF: 472.72

Purity: ≥95%

Appearance: White to off-white solid

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Storage: Store at -20 °C

Density: 1.10±0.1 g/cm3

Melting Point: 226-227 °C

InChIKey: FZXFJQVZSQAGPM-VDHUWJSZSA-N

CanonicalSMILES: CC(C)(C)[Si](C)(C)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=CC(=O)NC2=O)CO

IUPAC Name: 1-((2R,3R,4R,5R)-3,4-bis((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

InChI: InChI=1S/C21H40N2O6Si2/c1-20(2,3)30(7,8)28-16-14(13-24)27-18(23-12-11-15(25)22-19(23)26)17(16)29-31(9,10)21(4,5)6/h11-12,14,16-18,24H,13H2,1-10H3,(H,22,25,26)/t14-,16-,17-,18-/m1/s1

Synonyms: Uridine, 2',3'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-; 2',3'-Bis-O-tert-butyldimethylsilyluridine; 2'-O,3'-O-Bis(tert-butyldimethylsilyl)uridine; 2',3'-Bis-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine; 2',3'-Bis-O-[(1,1-dimethylethyl)dimethylsilyl]uridine

1-(b-D-Xylofuranosyl)cytosine

Description: 1-(b-D-Xylofuranosyl)cytosine, a nucleoside analog, exhibits remarkable potency as an antiviral agent, finding utility in combating viral infections induced by pathogens such as Herpes simplex virus, Varicella-zoster virus, and Epstein-Barr virus. By impeding viral DNA synthesis, this compound serves as a pivotal tool in thwarting viral replication.

CAT: BRP-01801

CAS: 3530-56-1

MF: C9H13N3O5

MF: 243.22

Purity: ≥95%

Appearance: White to Off-white Powder

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Storage: Store at 2-8 °C

Density: 1.89±0.1 g/cm3

Melting Point: 237-238°C

Boiling Point: 545.7±60.0°C at 760 mmHg

InChIKey: UHDGCWIWMRVCDJ-PXBUCIJWSA-N

CanonicalSMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O

IUPAC Name: 4-amino-1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6+,7-,8-/m1/s1

Synonyms: Xylocytidine; Xylo-cytidine; 4-Amino-1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 4-Amino-1-β-D-xylofuranosyl-2(1H)-pyrimidinone; Cytosine, 1-β-D-xylofuranosyl-; 1-(β-D-Xylofuranosyl)cytosine

9-(b-D-Xylofuranosyl)guanine

Description: 9-(β-D-Xylofuranosyl)guanine, a renowned biomedicine product, is widely recognized for its efficaciousness in combating viral infections, particularly those induced by herpes viruses. Functioning as an antiviral agent, this compound effectively hinders the proliferation of viral DNA, thereby mitigating viral burden and alleviating symptoms related to herpes virus infections.

CAT: BRP-01803

CAS: 27462-39-1

MF: C10H13N5O5

MF: 283.24

Purity: ≥95%

Appearance: White to off-white solid

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Storage: Store at 2-8 °C

Density: 2.25±0.1 g/cm3

Boiling Point: 775.9±70.0°C at 760 mmHg

InChIKey: NYHBQMYGNKIUIF-FTWQFJAYSA-N

CanonicalSMILES: C1=NC2=C(N1C3C(C(C(O3)CO)O)O)N=C(NC2=O)N

IUPAC Name: 2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5+,6-,9-/m1/s1

Synonyms: 6H-Purin-6-one, 1,9-dihydro-2-amino-9-beta-D-xylofuranosyl-; 2-Amino-9-(β-D-xylofuranosyl)-1,9-dihydro-6H-purin-6-one; 2-Amino-9-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 2-Amino-1,9-dihydro-9-β-D-xylofuranosyl-6H-purin-6-one; Guanine, 9-β-D-xylofuranosyl-; 9-β-D-Xylofuranosylguanine; NSC 115607

6-Methyl-9-(beta-D-ribofuranosyl)-9H-purine

Description: It is a natural antibiotic, antifungal and antiviral agent.

CAT: BRP-01805

CAS: 14675-48-0

MF: C11H14N4O4

MF: 266.25

Purity: ≥95%

Appearance: White solid

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Storage: Store at -20°C

Density: 1.81±0.1 g/cm3 (Predicted)

Melting Point: 209-210°C

Boiling Point: 590.4±60.0°C (Predicted)

InChIKey: FIGBCBGMUIGJBD-PNHWDRBUSA-N

CanonicalSMILES: CC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O

IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-methylpurin-9-yl)oxolane-3,4-diol

InChI: InChI=1S/C11H14N4O4/c1-5-7-10(13-3-12-5)15(4-14-7)11-9(18)8(17)6(2-16)19-11/h3-4,6,8-9,11,16-18H,2H2,1H3/t6-,8-,9-,11-/m1/s1

Synonyms: 6-D-MPR; 9H-Purine, 6-methyl-9-b-D-ribofuranosyl-; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)tetrahydrofuran-3,4-diol; 6-Methylpurine-beta-D-ribonucleoside; 6-Methyl-9-β-D-ribofuranosylpurine; NSC 101619; 6-Methylpurine ribonucleoside

3'-O-TBDMS-N2-Isobutyryl-Guanosine

Description: 3'-O-TBDMS-N2-Isobutyryl-Guanosine is an impressive and versatile nucleotide analog with burgeoning potential. Frequently deployed as a biochemical tool in modified RNA synthesis, it also boasts functionality as a viral RNA-dependent RNA polymerase substrate. A captivatingly multifaceted compound, studies to date suggest its exceptional capacity to combat viral infections, including Hepatitis C and Zika virus.

CAT: BRP-01807

CAS: 1237684-87-5

MF: C20H33N5O6Si

MF: 467.60

Purity: ≥95% by HPLC

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Density: 1.37±0.1 g/cm3

InChIKey: MCKWRFWFUTWNLD-XWXWGSFUSA-N

CanonicalSMILES: CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O[Si](C)(C)C(C)(C)C)O

IUPAC Name: N-(9-((2R,3R,4S,5R)-4-((tert-butyldimethylsilyl)oxy)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

InChI: InChI=1S/C20H33N5O6Si/c1-10(2)16(28)23-19-22-15-12(17(29)24-19)21-9-25(15)18-13(27)14(11(8-26)30-18)31-32(6,7)20(3,4)5/h9-11,13-14,18,26-27H,8H2,1-7H3,(H2,22,23,24,28,29)/t11-,13-,14-,18-/m1/s1

Synonyms: Guanosine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-; 3'-O-[Dimethyl(2-methyl-2-propanyl)silyl]-N-isobutyrylguanosine; 3'-O-[(1,1-Dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine