Nucleosides - RNA / BOC Sciences

3-Methyluridine

Description: 3-Methyluridine is a modified nucleoside of RNA.

CAT: BRP-01736

CAS: 2140-69-4

MF: C10H14N2O6

MF: 258.23

Purity: ≥95%

Appearance: White Crystalline Powder

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Storage: Store at -20°C

Density: 1.605±0.06 g/cm3 (Predicted)

Melting Point: 113-115°C

Boiling Point: 501.1±60.0°C (Predicted)

Application: 3-Methyluridine is a modified nucleoside of RNA.

Symbol: m³U

InChIKey: UTQUILVPBZEHTK-ZOQUXTDFSA-N

Solubility: Soluble in DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly, Sonicated)

CanonicalSMILES: CN1C(=O)C=CN(C1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-methylpyrimidine-2,4-dione

InChI: InChI=1S/C10H14N2O6/c1-11-6(14)2-3-12(10(11)17)9-8(16)7(15)5(4-13)18-9/h2-3,5,7-9,13,15-16H,4H2,1H3/t5-,7-,8-,9-/m1/s1

Synonyms: N3-Methyl Uridine; N3-Methyluridine; N-3-Methyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3-methylpyrimidine-2,4(1H,3H)-dione; NSC 246077; 3-Methyl-uridine; 3-Methyl-1-(β-L-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione

N6-Phenoxyacetyladenosine

Description: N6-Phenoxyacetyladenosine is an extensively utilized compound in the biomedical sector, serving as a noteworthy resource for investigating adenosine receptors. This compound displays heightened affinity towards diverse subtypes of adenosine receptors due to its distinctive structural alteration.

CAT: BRP-01737

CAS: 119824-65-6

MF: C18H19N5O6

MF: 401.37

Purity: ≥95%

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Density: 1.67±0.1 g/cm3

Melting Point: 110-112°C

InChIKey: FLHMVFSWPWAGQW-XKLVTHTNSA-N

Solubility: Soluble in Ethanol, Water

CanonicalSMILES: C1=CC=C(C=C1)OCC(=O)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]-2-phenoxyacetamide

InChI: InChI=1S/C18H19N5O6/c24-6-11-14(26)15(27)18(29-11)23-9-21-13-16(19-8-20-17(13)23)22-12(25)7-28-10-4-2-1-3-5-10/h1-5,8-9,11,14-15,18,24,26-27H,6-7H2,(H,19,20,22,25)/t11-,14-,15-,18-/m1/s1

Synonyms: N6-PAc-rA; PAc-rA; N6-PAc-adenosine; ribo Adenosine (n-PAC); N-(Phenoxyacetyl)adenosine; N-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)-2-phenoxyacetamide; Adenosine, N-(2-phenoxyacetyl)-; N-(2-Phenoxyacetyl)adenosine

N4-Benzoyl-5-methylcytidine

Description: N4-Benzoyl-5-methylcytidine, an extraordinary biomedical compound, emerges as a pivotal player in combating diverse ailments. This remarkable agent manifests indispensible significance in precise drug or therapy delivery for cancer eradication, antiviral remedy, and genic treatment.

CAT: BRP-01738

CAS: 160107-15-3

MF: C17H19N3O6

MF: 361.35

Purity: 98%

Appearance: White to Off-white Powder

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Storage: Store at 2-8°C

Density: 1.55±0.1 g/cm3 (Predicted)

InChIKey: NVJJYVKITRVBHJ-BRXULGCHSA-N

Solubility: Soluble in Methanol

CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)CO)O)O

IUPAC Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C17H19N3O6/c1-9-7-20(16-13(23)12(22)11(8-21)26-16)17(25)19-14(9)18-15(24)10-5-3-2-4-6-10/h2-7,11-13,16,21-23H,8H2,1H3,(H,18,19,24,25)/t11-,12-,13-,16-/m1/s1

Synonyms: 5-Methyl-cytidine (N-Bz); N4-Benzoyl-5-methyl-D-cytidine; N-Benzoyl-5-methylcytidine; N-(1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide

1-(6-Amino-9-β-D-ribofuranosyl-9H-purin-2-yl)-1H-pyrazole-4-carboxylic Acid Ethyl Ester

Description: A short-acting A2A adenosine receptor agonist.

CAT: BRP-01745

CAS: 313348-16-2

MF: C16H19N7O6

MF: 405.37

Purity: ≥98%

Appearance: Yellow Powder

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Density: 1.89±0.1 g/cm3

Boiling Point: 823.5±75.0 °C at 760 mmHg

InChIKey: ZPVLTIXYQGANFL-IDTAVKCVSA-N

Solubility: Soluble in Dimethyl Formamide

CanonicalSMILES: CCOC(=O)C1=CN(N=C1)C2=NC(=C3C(=N2)N(C=N3)C4C(C(C(O4)CO)O)O)N

IUPAC Name: ethyl 1-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]pyrazole-4-carboxylate

InChI: InChI=1S/C16H19N7O6/c1-2-28-15(27)7-3-19-23(4-7)16-20-12(17)9-13(21-16)22(6-18-9)14-11(26)10(25)8(5-24)29-14/h3-4,6,8,10-11,14,24-26H,2,5H2,1H3,(H2,17,20,21)/t8-,10-,11-,14-/m1/s1

Synonyms: 1H-Pyrazole-4-carboxylic acid, 1-(6-amino-9-β-D-ribofuranosyl-9H-purin-2-yl)-, ethyl ester; CVT 3127; CVT3127; CVT-3127; Regadenoson Impurity; Ethyl 1-(6-amino-9-β-D-ribofuranosyl-9H-purin-2-yl)-1H-pyrazole-4-carboxylate

5-Methoxycytidine

Description: 5-Methoxycytidine is an indispensable pharmaceutical compound, showcasing immense potential in the realm of disease research, especially cancer. Its significant ability to impede the expansion and multiplication of malignant cells substantiates its worth as an invaluable weapon in the ongoing research and development of anti-cancer drugs.

CAT: BRP-01758

CAS: 37805-90-6

MF: C10H15N3O6

MF: 273.24

Purity: ≥95%

Appearance: White to Off-white powder

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Storage: Store at 2-8 °C

Density: 1.81±0.1 g/cm3 (Predicted)

Boiling Point: 569.9±60.0 °C at 760 mmHg

InChIKey: IZFJAICCKKWWNM-JXOAFFINSA-N

CanonicalSMILES: COC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O

IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxypyrimidin-2-one

InChI: InChI=1S/C10H15N3O6/c1-18-4-2-13(10(17)12-8(4)11)9-7(16)6(15)5(3-14)19-9/h2,5-7,9,14-16H,3H2,1H3,(H2,11,12,17)/t5-,6-,7-,9-/m1/s1

Synonyms: 5-Methoxy cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidin-2(1H)-one; NSC 339193; 5-OMe-Cr

N6-(4-Methyoxybenzoyl)adenosine

Description: N6-(4-Methoxybenzoyl)adenosine, a chemical compound, finds its essential use in investigating adenosine receptors in the domain of biomedicine, towards seeking cures for a diverse range of diseases. Its therapeutic potential is particularly noteworthy and extends to neurological conditions like Parkinson's disease and Alzheimer's disease, not to forget the noteworthy anti-inflammatory effects it has on cardiovascular diseases. The effective binding to adenosine receptors makes it fertile ground for exploring wider possibilities in the study of diseases.

CAT: BRP-01761

CAS: 56883-05-7

MF: C18H19N5O6

MF: 401.37

Purity: ≥97% by HPLC

Appearance: White to pale yellow solid

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Storage: Store at -20°C

Density: 1.67±0.1 g/cm3 (Predicted)

InChIKey: YDVLBCYELIMFHS-XWXWGSFUSA-N

CanonicalSMILES: COC1=CC=C(C=C1)C(=O)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]-4-methoxybenzamide

InChI: InChI=1S/C18H19N5O6/c1-28-10-4-2-9(3-5-10)17(27)22-15-12-16(20-7-19-15)23(8-21-12)18-14(26)13(25)11(6-24)29-18/h2-5,7-8,11,13-14,18,24-26H,6H2,1H3,(H,19,20,22,27)/t11-,13-,14-,18-/m1/s1

Synonyms: N6-Anisoyladenosine; Adenosine, N-(4-methoxybenzoyl)-; N-(p-Anisoyl)adenosine; N-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)-4-methoxybenzamide; N-(4-Methoxybenzoyl)adenosine; 6-N-p-Anisoyladenosine

N2-Phenoxyacetylguanosine

Description: N2-Phenoxyacetylguanosine, a renowned biomedical compound, garners attention due to its exceptional anti-viral qualities. Refined scientific research highlights its profound role as a potent inhibitor, effectively impeding the replication processes of select viruses through specific targeting of their viral enzymes. This exceptional product exhibits remarkable efficacy in combating viral infections triggered by distinct RNA viruses. Intriguingly, its mechanism of action disrupts viral RNA synthesis, presenting immense prospects for the development of avant-garde antiviral therapies.

CAT: BRP-01762

CAS: 119824-66-7

MF: C18H19N5O7

MF: 417.37

Purity: ≥95%

Appearance: White to Yellow Crystalline Powder

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Storage: Store at 2-8°C

Density: 1.76±0.10 g/cm3

Melting Point: 159-160 °C

InChIKey: FOOYAXZEBFXEJD-IWCJZZDYSA-N

CanonicalSMILES: C1=CC=C(C=C1)OCC(=O)NC2=NC3=C(C(=O)N2)N=CN3C4C(C(C(O4)CO)O)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-phenoxyacetamide

InChI: InChI=1S/C18H19N5O7/c24-6-10-13(26)14(27)17(30-10)23-8-19-12-15(23)21-18(22-16(12)28)20-11(25)7-29-9-4-2-1-3-5-9/h1-5,8,10,13-14,17,24,26-27H,6-7H2,(H2,20,21,22,25,28)/t10-,13-,14-,17-/m1/s1

Synonyms: Gua(pac); 2-N-phenoxyacetylguanosine; N-[9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl]-2-phenoxy-acetamide; N-(Phenoxyacetyl)guanosine; ribo Guanosine (n-PAC); N2-PAC-rG; N-(2-Phenoxyacetyl)guanosine

5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine

Description: 5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine, a compound widely employed in the realm of biomedicine, encapsulates vast prospects for therapeutic interventions in an array of ailments, encompassing viral infections and select malignancies. Possessing an idiosyncratic molecular configuration, this enigmatic substance has attained an eminent stance within drug exploration and advancement, particularly pertaining to nucleoside chemistry.

CAT: BRP-01763

CAS: 251647-51-5

MF: C33H36N2O9

MF: 604.65

Purity: ≥98% by HPLC

Appearance: White to Faint Yellow Powder

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Storage: Store at 2-8°C

Density: 1.34±0.1 g/cm3(Predicted)

InChIKey: YVYKKLNOXPCFGC-PMFUCWTESA-N

CanonicalSMILES: COCCOC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O

IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C33H36N2O9/c1-39-19-20-42-30-29(37)27(44-31(30)35-18-17-28(36)34-32(35)38)21-43-33(22-7-5-4-6-8-22,23-9-13-25(40-2)14-10-23)24-11-15-26(41-3)16-12-24/h4-18,27,29-31,37H,19-21H2,1-3H3,(H,34,36,38)/t27-,29-,30-,31-/m1/s1

Synonyms: 5'-O-DMT-2'-O-(2-Methoxyethyl)-Uridine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)uridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)uridine; 5'-O-DMT-2'-O-MOE-Ur

N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-cytidine

Description: N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-cytidine, an influential nucleoside analogue with potent antiviral properties, is extensively employed across the biomedical sector. Its remarkable efficacy extends to a diverse range of DNA and RNA viruses, encompassing herpesvirus, papillomavirus, and retroviruses. Notably, this compound showcases promising outcomes in impeding viral replication, thereby presenting itself as a promising therapeutic avenue for combating viral infections and associated ailments.

CAT: BRP-01764

CAS: 251647-49-1

MF: C40H41N3O9

MF: 707.77

Purity: ≥95%

Appearance: White to Off-white Powder or Crystals

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Storage: Store at -20°C

Density: 1.26±0.1 g/cm3 (Predicted)

InChIKey: PRAZQDMVAGLVKR-XHOUGWTJSA-N

CanonicalSMILES: COCCOC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C40H41N3O9/c1-47-24-25-50-36-35(44)33(52-38(36)43-23-22-34(42-39(43)46)41-37(45)27-10-6-4-7-11-27)26-51-40(28-12-8-5-9-13-28,29-14-18-31(48-2)19-15-29)30-16-20-32(49-3)21-17-30/h4-23,33,35-36,38,44H,24-26H2,1-3H3,(H,41,42,45,46)/t33-,35-,36-,38-/m1/s1

Synonyms: 5'-O-DMT-N4-BZ-2'-O-(2-Methoxyethyl)-Cytidine; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)cytidine; N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-(2-methoxyethyl)cytidine; 5'-O-DMT-2'-O-MOE-C(Bz)

Arabinofuranosyl-hypoxanthine (ara-HX)

Description: Arabinofuranosyl-hypoxanthine is a prodrug of Vidarabine for improving the oral bioavailability, which is an antiviral drug. It is an antimetabolic nucleoside that inhibits Streptococcus pyogenes and other bacteria, as well as zirconium oxide, pulmonary vasodilation, squamous cell carcinoma, and rate constant.

CAT: BRP-01769

CAS: 7013-16-3

MF: C10H12N4O5

MF: 268.22

Purity: ≥98%

Appearance: White or off-white solid

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Storage: Store at 2-8 °C

Density: 2.08±0.1 g/cm3

Melting Point: 259-260 °C

Boiling Point: 797.9±60.0 °C at 760 mmHg

Application: Antiviral Agents

InChIKey: UGQMRVRMYYASKQ-UHTZMRCNSA-N

Solubility: Soluble in DMSO (Slightly), Water (Slightly)

CanonicalSMILES: C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)CO)O)O

IUPAC Name: 9-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6-,7+,10-/m1/s1

Synonyms: Arabinofuranosyl-hypoxanthine; Arabino inosine; 9-β-D-Arabinofuranosyl-1,9-dihydro-6H-purin-6-one; Hypoxanthine, 9-β-D-arabinofuranosyl-; 9-β-D-Arabinofuranosylhypoxanthine; Ara-H; Arabinosylhypoxanthine; Arainosine; Hypoxanthine arabinoside; NSC 405122; 9-(β-D-Arabinofuranosyl)-hypoxanthine

2-Amino-9-(2-O-methyl-β-D-ribofuranosyl)purine

Description: 2-Amino-9-(2-O-methyl-β-D-ribofuranosyl)purine is a renowned pharmaceutical compound, boasting its exceptional potency as an antiviral agent. With a distinctive focus on combating the likes of hepatitis C and diverse DNA viruses, this product manifests remarkable efficacy in hindering viral replication.

CAT: BRP-01770

CAS: 274259-35-7

MF: C11H15N5O4

MF: 281.27

Purity: ≥97%

Appearance: White or off-white solid

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Storage: Store at 2-8 °C

Density: 1.84±0.1 g/cm3

Boiling Point: 654.1±65.0 °C at 760 mmHg

InChIKey: UQKXGJSZRSHLBF-FDDDBJFASA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=CN=C(N=C32)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(2-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol

InChI: InChI=1S/C11H15N5O4/c1-19-8-7(18)6(3-17)20-10(8)16-4-14-5-2-13-11(12)15-9(5)16/h2,4,6-8,10,17-18H,3H2,1H3,(H2,12,13,15)/t6-,7-,8-,10-/m1/s1

Synonyms: 2-Amino-9-(2'-O-methyl-beta-D-ribofuranosyl)-9H-purine; 9-(2-O-Methyl-β-D-ribofuranosyl)-9H-purin-2-amine; 2-Amino-9-(2-o-methyl-β-d-ribofuranosyl)purine

2-Thiocytidine

Description: 2-Thiocytidine, a nucleoside analogue, is a potent anti-cancer agent that shows promise in treating several types of cancer, including leukemia, lymphoma, and solid tumors. Through interference with the DNA synthesis process, it effectively halts cancer cell growth, while also demonstrating antiviral activity towards HIV and hepatitis B. From these qualities, it is clear that 2-Thiocytidine holds tremendous potential as a therapeutic agent for the treatment of cancer and viral infections.

CAT: BRP-01771

CAS: 13239-97-9

MF: C9H13N3O4S

MF: 259.28

Purity: ≥95%

Appearance: Off-white to Dark Brown Solid

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Storage: Store at -20°C under inert atmosphere

Density: 1.85±0.1 g/cm3(Predicted)

Melting Point: 208-209 °C

Boiling Point: 540.5±60.0 °C at 760 mmHg

Symbol: s²C

InChIKey: RHFUOMFWUGWKKO-XVFCMESISA-N

Solubility: Soluble in Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=CN(C(=S)N=C1N)C2C(C(C(O2)CO)O)O

IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2-thione

InChI: InChI=1S/C9H13N3O4S/c10-5-1-2-12(9(17)11-5)8-7(15)6(14)4(3-13)16-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,17)/t4-,6-,7-,8-/m1/s1

Synonyms: Cytidine, 2-thio-; 4-amino-1-beta-D-ribofuranosylpyrimidine-2(1H)-thione; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2(1H)-thione; 2(1H)-Pyrimidinethione, 4-amino-1-β-D-ribofuranosyl-

2'-O-Methyl-2-thiouridine

Description: 2'-O-Methyl-2-thiouridine is a valuable compound widely used in biomedicine. It acts as an RNA modification tool, incorporating into RNA molecules during synthesis. This powerful molecule exhibits antiviral activity against various viral infections, making it a potential therapeutic option for treating RNA virus-associated diseases. Its unique properties and versatility make it an essential tool for studying RNA biology and developing antiviral therapies.

CAT: BRP-01772

CAS: 113886-72-9

MF: C10H14N2O5S

MF: 274.29

Purity: ≥95%

Appearance: Off-white to Brown Powder

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Storage: Store at 2-8 °C

Density: 1.55±0.1 g/cm3 (Predicted)

Symbol: s²Um

InChIKey: WARUUAMZJXEUEA-ZOQUXTDFSA-N

CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)NC2=S)CO)O

IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2-sulfanylidenepyrimidin-4-one

InChI: InChI=1S/C10H14N2O5S/c1-16-8-7(15)5(4-13)17-9(8)12-3-2-6(14)11-10(12)18/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,18)/t5-,7-,8-,9-/m1/s1

Synonyms: 2-thio-2'-O-methyluridine; Uridine, 2'-O-methyl-2-thio-; 1-(2-O-Methyl-β-D-ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 4(1H)-Pyrimidinone, 2,3-dihydro-1-(2-O-methyl-β-D-ribofuranosyl)-2-thioxo-; 1-((2R,3R,4R,5R)-4-Hydroxy-5-hydroxymethyl-3-methoxy-tetrahydro-furan-2-yl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

N4-Aminocytidine

Description: N4-Aminocytidine is a cytidine analog where an amino group is attached to the nitrogen at the 4th position of the cytosine base. This modification can be used in biochemical and molecular biology research to study nucleic acid interactions, enzymatic activity, and as a potential antiviral or anticancer agent. The presence of the additional amino group can influence base pairing and the overall stability of nucleic acids, providing a useful tool for exploring nucleic acid structure and function. It inhibits the growth of Escherichia coli and Salmonella typhimurium in vitro. It binds to the bacterial ribosome and inhibits protein synthesis, which results in cell death.

CAT: BRP-01773

CAS: 57294-74-3

MF: C9H14N4O5

MF: 258.23

Purity: ≥98%

Appearance: White or off-white solid

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Storage: Store at 2-8 °C

Density: 1.93±0.1 g/cm3

InChIKey: RSSRMDMJEZIUJX-XVFCMESISA-N

Solubility: Soluble in DMSO (Slightly), Water (Slightly)

CanonicalSMILES: C1=CN(C(=O)N=C1NN)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydrazinylpyrimidin-2-one

InChI: InChI=1S/C9H14N4O5/c10-12-5-1-2-13(9(17)11-5)8-7(16)6(15)4(3-14)18-8/h1-2,4,6-8,14-16H,3,10H2,(H,11,12,17)/t4-,6-,7-,8-/m1/s1

Synonyms: Uridine, 4-hydrazone; Uridine 4-hydrazone; Cytidine, N-amino-; EIDD 1910; N-Aminocytidine; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydrazinylpyrimidin-2(1H)-one

5-Bromocytidine

Description: 5-Bromocytidine, an indispensable biomedicine compound, holds immense promise for combating viral infections and cancer. Functioning as a nucleoside analog, it effectively impedes the replication of viral RNA and DNA. Moreover, its integration into cellular nucleic acids and subsequent interference with their synthesis inflict cytotoxicity upon cancer cells.

CAT: BRP-01774

CAS: 3066-86-2

MF: C9H12BrN3O5

MF: 322.11

Purity: ≥95%

Appearance: White to Off-white Crystalline Powder

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Storage: Store at 2-8°C

Density: 2.28±0.1 g/cm3 (Predicted)

Melting Point: 183-185°C

Boiling Point: 555.4±60.0°C (Predicted)

InChIKey: HRDXGYQCVPZEJE-UAKXSSHOSA-N

CanonicalSMILES: C1=C(C(=NC(=O)N1C2C(C(C(O2)CO)O)O)N)Br

IUPAC Name: 4-amino-5-bromo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

InChI: InChI=1S/C9H12BrN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1

Synonyms: 5-Bromo-ribo Cytidine; 4-amino-5-bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 5-Bromo-D-cytidine

N2,N2-Dimethylguanosine

Description: N2,N2-Dimethylguanosine is a modified nucleoside where two methyl groups are attached to the nitrogen at the second position of the guanine base. This modification can affect hydrogen bonding and base pairing within nucleic acids. It is often found in tRNA and other RNA molecules, contributing to their stability and function. In biochemical research, N2,N2-dimethylguanosine is used to study enzyme interactions and the impact of methylation on nucleic acid structure and function.

CAT: BRP-01775

CAS: 2140-67-2

MF: C12H17N5O5

MF: 311.29

Purity: ≥95%

Appearance: White to Pale Beige Solid

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Storage: Store at -20°C

Density: 1.83±0.1 g/cm3 (Predicted)

Melting Point: >218°C (dec.)

Boiling Point: 683.6°C at 760 mmHg

Symbol: m²₂G

InChIKey: RSPURTUNRHNVGF-IOSLPCCCSA-N

Solubility: Soluble in DMSO (Slightly, Heated), Methanol (Slightly, Heated)

CanonicalSMILES: CN(C)C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-(dimethylamino)-1H-purin-6-one

InChI: InChI=1S/C12H17N5O5/c1-16(2)12-14-9-6(10(21)15-12)13-4-17(9)11-8(20)7(19)5(3-18)22-11/h4-5,7-8,11,18-20H,3H2,1-2H3,(H,14,15,21)/t5-,7-,8-,11-/m1/s1

Synonyms: N,N-Dimethylguanosine; N2-Dimethylguanosine; 2,2-Dimethylguanosine; 2-Dimethylamino-6-oxypurine riboside; 2-Dimethylguanosine; 2-(dimethylamino)-9-(beta-D-ribofuranosyl)-1,9-dihydro-6H-purin-6-one; 9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-(dimethylamino)-1H-purin-6(9H)-one

5,6-Dihydrouridine

Description: 5,6-Dihydrouridine is an intermediate used in the synthesis of 3,4,5,6-Tetrahydrouridine (>80%), which is a derivative of Uridine. Tetrahydrouridine (THU) is a potent inhibitor of cytidine. It inhibits cell proliferation through cell cycle regulation regardless of cytidine deaminase expression levels deaminase (CDA), and thus can be used as a potential and promising treatment for tumors with highly expressed CDA.

CAT: BRP-01777

CAS: 5627-05-4

MF: C9H14N2O6

MF: 246.22

Purity: ≥95%

Appearance: White to Off-White Solid

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Storage: Store at 2-8°C under inert atmosphere

Density: 1.614±0.06 g/cm3 (Predicted)

Melting Point: >64°C (dec.)

Symbol: D

InChIKey: ZPTBLXKRQACLCR-XVFCMESISA-N

Solubility: Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione

InChI: InChI=1S/C9H14N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4,6-8,12,14-15H,1-3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1

Synonyms: Dihydro-1-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione; Dihydrouridine; 1-β-D-Ribofuranosyl-hydrouracil; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)dihydropyrimidine-2,4(1H,3H)-dione; 1-(β-L-Ribofuranosyl)dihydro-2,4(1H,3H)-pyrimidinedione

2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]inosine

Description: 2-Fluoro-6-O-[2-(4-nitrophenyl)ethyl]inosine is a remarkable and transformative compound research and development, manifesting its remarkable potential in research of an array of incessant and pernicious viral infections. As a meticulously tailored nucleoside analog, this compound exerts its magnificent influence by diligently thwarting the relentless propagation of notorious entities such as herpes simplex virus (HSV) and human immunodeficiency virus (HIV).

CAT: BRP-01778

CAS: 171284-49-4

MF: C18H18FN5O7

MF: 435.36

Purity: ≥95%

Appearance: White or off-white solid

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Storage: Store at 2-8 °C

Density: 1.76±0.1 g/cm3

Boiling Point: 811.6±75.0 °C at 760 mmHg

InChIKey: XUQAGOPCIUTOKD-LSCFUAHRSA-N

CanonicalSMILES: C1=CC(=CC=C1CCOC2=NC(=NC3=C2N=CN3C4C(C(C(O4)CO)O)O)F)[N+](=O)[O-]

IUPAC Name: (2R,3R,4S,5R)-2-[2-fluoro-6-[2-(4-nitrophenyl)ethoxy]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol

InChI: InChI=1S/C18H18FN5O7/c19-18-21-15-12(20-8-23(15)17-14(27)13(26)11(7-25)31-17)16(22-18)30-6-5-9-1-3-10(4-2-9)24(28)29/h1-4,8,11,13-14,17,25-27H,5-7H2/t11-,13-,14-,17-/m1/s1

Synonyms: 2-Fluoro-O6-(p-nitrophenylethyl)-9-b-D-ribofuranosyl)purine; 2-Fluoro-9-(beta-D-ribofuranosyl)-6-[2-(4-nitrophenyl)ethoxy]-9H-purine; (2R,3R,4S,5R)-2-{2-Fluoro-6-[2-(4-nitro-phenyl)-ethoxy]-purin-9-yl}-5-hydroxymethyl-tetrahydro-furan-3,4-diol; 2-fluoro-O6-[2-(4-nitrophenyl)ethyl]inosine

8-Azaguanosine

Description: 8-Azaguanosine is a modified nucleoside where a nitrogen atom replaces the carbon at the eighth position of the guanine base. This alteration can impact base pairing and hydrogen bonding properties. It is used in biochemical and molecular biology research to study nucleic acid interactions, enzyme activity, and the structural effects of nucleobase modifications. Additionally, 8-azaguanosine is investigated for its potential antiviral and anticancer properties due to its ability to interfere with nucleic acid metabolism.

CAT: BRP-01779

CAS: 2133-80-4

MF: C9H12N6O5

MF: 284.23

Purity: ≥95%

Appearance: Pale yellow solid

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Storage: Store at 2-8 °C

Density: 2.49±0.1 g/cm3 (Predicted)

Melting Point: 250-252°C (dec.)

Boiling Point: 567.3°C at 760 mmHg

InChIKey: QOVIBFFZCVPCEI-UMMCILCDSA-N

Solubility: Soluble in Water

CanonicalSMILES: C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=N2)O)O)O

IUPAC Name: 5-amino-3-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6H-triazolo[4,5-d]pyrimidin-7-one

InChI: InChI=1S/C9H12N6O5/c10-9-11-6-3(7(19)12-9)13-14-15(6)8-5(18)4(17)2(1-16)20-8/h2,4-5,8,16-18H,1H2,(H3,10,11,12,19)/t2-,4-,5-,8-/m1/s1

Synonyms: Azaguanosine; NSC 46788; NSC 130283; 5-Amino-3,6-dihydro-3-β-D-ribofuranosyl-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one; 3H-v-Triazolo[4,5-d]pyrimidin-7(6H)-one, 5-amino-3-β-D-ribofuranosyl-; 3H-v-Triazolo[4,5-d]pyrimidin-7-ol, 5-amino-3-β-D-ribofuranosyl-; 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,4-dihydro-3-β-D-ribofuranosyl-; 7H-v-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,6-dihydro-3-β-D-ribofuranosyl-

2-Thiouridine

Description: 2-Thiouridine, an esteemed biomedical marvel, is renowned for its profound efficacy in combatting malignant neoplasms and thwarting viral affections. This exalted nucleoside derivative ingeniously integrates itself into RNA, instigating the impeding of viral propagation and invoking apoptosis within neoplastic entities. Its exceptional anti-tumorigenic and antiviral prowess has propelled 2-Thiouridine to the vanguard of biomedical exploration and therapeutic breakthroughs.

CAT: BRP-01780

CAS: 20235-78-3

MF: C9H12N2O5S

MF: 260.27

Purity: ≥95%

Appearance: White to Off-white Solid

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Storage: Store at 2-8°C under inert atmosphere

Density: 1.72±0.1 g/cm3 at 20°C, 760 Torr

Melting Point: 216-218 °C

Symbol: s²U

InChIKey: GJTBSTBJLVYKAU-XVFCMESISA-N

Solubility: Soluble in DMSO (Slightly, Heated), Water (Slightly, Heated)

CanonicalSMILES: C1=CN(C(=S)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one

InChI: InChI=1S/C9H12N2O5S/c12-3-4-6(14)7(15)8(16-4)11-2-1-5(13)10-9(11)17/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,17)/t4-,6-,7-,8-/m1/s1

Synonyms: 1-β-D-Ribofuranosyl-2-thiouracil; 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; Thiouridine