Nucleosides

L-Uridine

Description: L-Uridine, a crucial nucleoside component harnessed for its role in promoting protein synthesis, boasts neuroprotective abilities, demonstrated in its function as a potent inhibitor of neuronal death while concurrently elevating neuroplasticity. Exhibiting efficacy in treating neurodegenerative ailments such as Alzheimer's and Parkinson's disease, L-Uridine further improves cognitive functions and memory. Its diverse range extends to addressing certain types of cancer and viral infections, positioning it to be a burgeoning therapeutic marvel.

CAT: BRP-01730

CAS: 26287-69-4

Molecular Formula: C9H12N2O6

Molecular Weight: 244.20

Purity: ≥99% by HPLC

Appearance: White to off-white crystalline powder

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Storage: Store at 2-8°C

Density: 1.674±0.06 g/cm3

InChIKey: DRTQHJPVMGBUCF-PSQAKQOGSA-N

CanonicalSMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m0/s1

Synonyms: Beta-L-ribo Uridine; 1-(b-L-ribofuranosyl)uracil; 1-((2S,3S,4R,5S)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-β-L-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione; Uracil, 1-β-L-ribofuranosyl-; β-L-Uridine

L-Inosine

Description: L-Inosine is a pivotal nucleoside, showcasing indispensible involvement in energy metabolism and purine nucleotide synthesis. Its profound significance thrives in the biomedical sector, where it acts as a adjunct for studying multifarious ailments such as immune-related disorders, neurodegenerative afflictions and cardiovascular maladies.

CAT: BRP-01731

CAS: 21138-24-9

Molecular Formula: C10H12N4O5

Molecular Weight: 268.23

Purity: ≥97% by HPLC

Appearance: Off-white Powder

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Storage: Store at -20°C

Density: 2.08 g/cm3

Melting Point: 218 °C

Boiling Point: 797.9±60.0 °C(Predicted)

InChIKey: UGQMRVRMYYASKQ-DEGSGYPDSA-N

CanonicalSMILES: C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)CO)O)O

IUPAC Name: 9-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6-,7-,10-/m0/s1

Synonyms: Beta-L-ribo Inosine; 9-((2S,3S,4R,5S)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 9-beta-L-Ribofuranosylhypoxanthine; L-ribofuranosyl-Inosine; 1,9-Dihydro-9-β-L-ribofuranosyl-6H-purin-6-one; Hypoxanthine, 9-β-L-ribofuranosyl-; 9-(β-L-Ribofuranosyl)-3,9-dihydro-6H-purin-6-one; β-L-Inosine

1,N6-Ethenoadenosine

Description: N6-Ethenoadenosine, a purine nucleoside analog, is paramount for the examination of oxidative damage on cellular DNA. It has demonstrated a capability to initiate DNA damage and apoptosis in cancer cells, rendering it an integral component of investigating its effectiveness as an anticancer agent. Its potential usage within the realm of cancer treatment necessitates a thorough understanding and exploration of its capabilities.

CAT: BRP-01732

CAS: 39007-51-7

Molecular Formula: C12H13N5O4

Molecular Weight: 291.26

Purity: ≥95% by HPLC

Appearance: White to Brown Crystalline Powder

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Storage: Store at -20°C

Density: 1.99±0.1 g/cm3

InChIKey: LRPBXXZUPUBCAP-WOUKDFQISA-N

CanonicalSMILES: C1=CN2C=NC3=C(C2=N1)N=CN3C4C(C(C(O4)CO)O)O

IUPAC Name: (2R,3S,4R,5R)-2-(hydroxymethyl)-5-imidazo[2,1-f]purin-3-yloxolane-3,4-diol

InChI: InChI=1S/C12H13N5O4/c18-3-6-8(19)9(20)12(21-6)17-5-14-7-10-13-1-2-16(10)4-15-11(7)17/h1-2,4-6,8-9,12,18-20H,3H2/t6-,8-,9-,12-/m1/s1

Synonyms: Etheno ribo Adenosine; N6-Etheno-D-adenosine; N6-Ethenoadenosine; 3-(β-D-Ribofuranosyl)-3H-imidazo[2,1-i]purine; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(3H-imidazo[2,1-i]purin-3-yl)tetrahydrofuran-3,4-diol; 3-β-D-Ribofuranosyl-3H-imidazo[2,1-i]purine; 1,6-Ethenoadenosine; Ethenoadenosine; N6-β-D-Ribosyl-1,N6-ethenoadenine; ε-Adenosine

N4-Ethenocytidine

Description: N4-Ethenocytidine, an indispensable compound within the biomedical industry, is of paramount significance. Its idiosyncratic molecular architecture renders it an ideal candidate for comprehensive research endeavors focusing on elucidating the intricate mechanisms underlying DNA methyltransferases' regulation and functionality. Profound insights gained from such investigations facilitate a holistic comprehension of the fundamental aspects of epigenetic modifications.

CAT: BRP-01733

CAS: 39007-52-8

Molecular Formula: C11H13N3O5

Molecular Weight: 267.24

Purity: ≥98% by HPLC

Appearance: White to off-white solid

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Density: 1.82±0.1 g/cm3

Boiling Point: 657.4±65.0 °C at 760 mmHg

InChIKey: DUCZQUFMCSTEHH-PEBGCTIMSA-N

CanonicalSMILES: C1=CN(C(=O)N2C1=NC=C2)C3C(C(C(O3)CO)O)O

IUPAC Name: 6-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazo[1,2-c]pyrimidin-5-one

InChI: InChI=1S/C11H13N3O5/c15-5-6-8(16)9(17)10(19-6)14-3-1-7-12-2-4-13(7)11(14)18/h1-4,6,8-10,15-17H,5H2/t6-,8-,9-,10-/m1/s1

Synonyms: Etheno ribo Cytidine; N4-Etheno-D-cytidine; Ethenocytidine; 6-β-D-Ribofuranosylimidazo[1,2-c]pyrimidin-5(6H)-one; 3,N4-Ethenocytidine

2,2'-Anhydrocytidine

Description: 2,2'-Anhydrocytidine, an intriguing compound highly regarded in the biomedical field, serves as a critical subject of research owing to its profound prospects in combatting viral infections, especially those instigated by RNA viruses.

CAT: BRP-01734

CAS: 31698-14-3

Molecular Formula: C9H11N3O4

Molecular Weight: 225.20

Purity: ≥95%

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Storage: Store at -20 °C

Density: 2.01±0.1 g/cm3

Melting Point: 249 °C (dec.)

Boiling Point: 422.2±55.0 °C at 760 mmHg

InChIKey: BBDAGFIXKZCXAH-CCXZUQQUSA-N

Solubility: Soluble in Methanol (Slightly), Water (Sparingly)

CanonicalSMILES: C1=CN2C3C(C(C(O3)CO)O)OC2=NC1=N

IUPAC Name: (2R,4R,5R,6S)-4-(hydroxymethyl)-10-imino-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-5-ol

InChI: InChI=1S/C9H11N3O4/c10-5-1-2-12-8-7(16-9(12)11-5)6(14)4(3-13)15-8/h1-2,4,6-8,10,13-14H,3H2/t4-,6-,7+,8-/m1/s1

Synonyms: Cytarabine Impurity H; (2R,3R,3aS,9aR)-2-(Hydroxymethyl)-6-imino-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-3-ol; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, (2R,3R,3aS,9aR)-; (2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-6-imino-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, [2R-(2α,3β,3aβ,9aβ)]-; 2,2'-Anhydro(1-β-D-arabinofuranosyl)cytosine; 2,2'-Anhydroarabinosylcytosine; 2,2'-Cyclocytidine; 2,2'-O-Cyclocytidine; Ancitabine; Ancytabine; Cyclocytidine; O2,2'-Cyclocytidine; O2:2'-Anhydro-1-β-D-arabinosylcytosine; Cytarabine EP Impurity H

Related CAS: 34939-46-3 (Deleted CAS) ; 36258-39-6 (Deleted CAS) ; 46488-37-3 (Deleted CAS) ; 51743-54-5 (Deleted CAS) ; 10212-25-6 (monohydrochloride)

2,2'-Cyclocytidine hydrochloride

Description: 2,2'-Anhydro-cytidine-HCl is a DNA synthesis inhibitor commonly used as an antineoplastic agent to treat leukemias.

CAT: BRP-01735

CAS: 10212-25-6

Molecular Formula: C9H12ClN3O4

Molecular Weight: 261.66

Purity: ≥95%

Appearance: White Crystalline Powder

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Storage: Store at -20°C

Density: 2.01 g/cm3

Melting Point: >230°C (dec.)

Boiling Point: 442°C at 760 mmHg

Flash Point: 221.1°C

InChIKey: KZOWNALBTMILAP-JBMRGDGGSA-N

Solubility: Soluble in Methanol (Slightly), Water (Sparingly)

CanonicalSMILES: C1=CN2C3C(C(C(O3)CO)O)OC2=NC1=N.Cl

IUPAC Name: (2R,4R,5R,6S)-4-(hydroxymethyl)-10-imino-3,7-dioxa-1,9-diazatricyclo[6.4.0.02,6]dodeca-8,11-dien-5-ol;hydrochloride

InChI: InChI=1S/C9H11N3O4.ClH/c10-5-1-2-12-8-7(16-9(12)11-5)6(14)4(3-13)15-8;/h1-2,4,6-8,10,13-14H,3H2;1H/t4-,6-,7+,8-;/m1./s1

Synonyms: Ancytabine Hydrochloride; 2,2'-Anhydro-(1-β-D-arabinofuranosyl)cytosine hydrochloride; Cyclocytidine Hydrochloride; 2,2'-Anhydrocytarabine HCl; 2,2'-O-Cyclocytidine Hydrochloride; Cyclo-CMP Hydrochloride; NSC 145668; O2,O2'-Anhydro-1-β-D-arabinofuranosylcytosine Monohydrochloride; [2R-(2α,3β,3aβ,9aβ)]-2,3,3a,9a-Tetrahydro-3-hydroxy-6-imino-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol Monohydrochloride

Related CAS: 31698-14-3 (free base)

3-Methyluridine

Description: 3-Methyluridine is a modified nucleoside of RNA.

CAT: BRP-01736

CAS: 2140-69-4

Molecular Formula: C10H14N2O6

Molecular Weight: 258.23

Purity: ≥95%

Appearance: White Crystalline Powder

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Storage: Store at -20°C

Density: 1.605±0.06 g/cm3 (Predicted)

Melting Point: 113-115°C

Boiling Point: 501.1±60.0°C (Predicted)

Application: 3-Methyluridine is a modified nucleoside of RNA.

Symbol: m³U

InChIKey: UTQUILVPBZEHTK-ZOQUXTDFSA-N

Solubility: Soluble in DMSO (Slightly, Heated), Methanol (Slightly, Heated), Water (Slightly, Sonicated)

CanonicalSMILES: CN1C(=O)C=CN(C1=O)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3-methylpyrimidine-2,4-dione

InChI: InChI=1S/C10H14N2O6/c1-11-6(14)2-3-12(10(11)17)9-8(16)7(15)5(4-13)18-9/h2-3,5,7-9,13,15-16H,4H2,1H3/t5-,7-,8-,9-/m1/s1

Synonyms: N3-Methyl Uridine; N3-Methyluridine; N-3-Methyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3-methylpyrimidine-2,4(1H,3H)-dione; NSC 246077; 3-Methyl-uridine; 3-Methyl-1-(β-L-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione

N6-Phenoxyacetyladenosine

Description: N6-Phenoxyacetyladenosine is an extensively utilized compound in the biomedical sector, serving as a noteworthy resource for investigating adenosine receptors. This compound displays heightened affinity towards diverse subtypes of adenosine receptors due to its distinctive structural alteration.

CAT: BRP-01737

CAS: 119824-65-6

Molecular Formula: C18H19N5O6

Molecular Weight: 401.37

Purity: ≥95%

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Density: 1.67±0.1 g/cm3

Melting Point: 110-112°C

InChIKey: FLHMVFSWPWAGQW-XKLVTHTNSA-N

Solubility: Soluble in Ethanol, Water

CanonicalSMILES: C1=CC=C(C=C1)OCC(=O)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]-2-phenoxyacetamide

InChI: InChI=1S/C18H19N5O6/c24-6-11-14(26)15(27)18(29-11)23-9-21-13-16(19-8-20-17(13)23)22-12(25)7-28-10-4-2-1-3-5-10/h1-5,8-9,11,14-15,18,24,26-27H,6-7H2,(H,19,20,22,25)/t11-,14-,15-,18-/m1/s1

Synonyms: N6-PAc-rA; PAc-rA; N6-PAc-adenosine; ribo Adenosine (n-PAC); N-(Phenoxyacetyl)adenosine; N-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)-2-phenoxyacetamide; Adenosine, N-(2-phenoxyacetyl)-; N-(2-Phenoxyacetyl)adenosine

N4-Benzoyl-5-methylcytidine

Description: N4-Benzoyl-5-methylcytidine, an extraordinary biomedical compound, emerges as a pivotal player in combating diverse ailments. This remarkable agent manifests indispensible significance in precise drug or therapy delivery for cancer eradication, antiviral remedy, and genic treatment.

CAT: BRP-01738

CAS: 160107-15-3

Molecular Formula: C17H19N3O6

Molecular Weight: 361.35

Purity: 98%

Appearance: White to Off-white Powder

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Storage: Store at 2-8°C

Density: 1.55±0.1 g/cm3 (Predicted)

InChIKey: NVJJYVKITRVBHJ-BRXULGCHSA-N

Solubility: Soluble in Methanol

CanonicalSMILES: CC1=CN(C(=O)N=C1NC(=O)C2=CC=CC=C2)C3C(C(C(O3)CO)O)O

IUPAC Name: N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C17H19N3O6/c1-9-7-20(16-13(23)12(22)11(8-21)26-16)17(25)19-14(9)18-15(24)10-5-3-2-4-6-10/h2-7,11-13,16,21-23H,8H2,1H3,(H,18,19,24,25)/t11-,12-,13-,16-/m1/s1

Synonyms: 5-Methyl-cytidine (N-Bz); N4-Benzoyl-5-methyl-D-cytidine; N-Benzoyl-5-methylcytidine; N-(1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide

1-(6-Amino-9-β-D-ribofuranosyl-9H-purin-2-yl)-1H-pyrazole-4-carboxylic Acid Ethyl Ester

Description: A short-acting A2A adenosine receptor agonist.

CAT: BRP-01745

CAS: 313348-16-2

Molecular Formula: C16H19N7O6

Molecular Weight: 405.37

Purity: ≥98%

Appearance: Yellow Powder

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Density: 1.89±0.1 g/cm3

Boiling Point: 823.5±75.0 °C at 760 mmHg

InChIKey: ZPVLTIXYQGANFL-IDTAVKCVSA-N

Solubility: Soluble in Dimethyl Formamide

CanonicalSMILES: CCOC(=O)C1=CN(N=C1)C2=NC(=C3C(=N2)N(C=N3)C4C(C(C(O4)CO)O)O)N

IUPAC Name: ethyl 1-[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]pyrazole-4-carboxylate

InChI: InChI=1S/C16H19N7O6/c1-2-28-15(27)7-3-19-23(4-7)16-20-12(17)9-13(21-16)22(6-18-9)14-11(26)10(25)8(5-24)29-14/h3-4,6,8,10-11,14,24-26H,2,5H2,1H3,(H2,17,20,21)/t8-,10-,11-,14-/m1/s1

Synonyms: 1H-Pyrazole-4-carboxylic acid, 1-(6-amino-9-β-D-ribofuranosyl-9H-purin-2-yl)-, ethyl ester; CVT 3127; CVT3127; CVT-3127; Regadenoson Impurity; Ethyl 1-(6-amino-9-β-D-ribofuranosyl-9H-purin-2-yl)-1H-pyrazole-4-carboxylate

5-Methoxycytidine

Description: 5-Methoxycytidine is an indispensable pharmaceutical compound, showcasing immense potential in the realm of disease research, especially cancer. Its significant ability to impede the expansion and multiplication of malignant cells substantiates its worth as an invaluable weapon in the ongoing research and development of anti-cancer drugs.

CAT: BRP-01758

CAS: 37805-90-6

Molecular Formula: C10H15N3O6

Molecular Weight: 273.24

Purity: ≥95%

Appearance: White to Off-white powder

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Storage: Store at 2-8 °C

Density: 1.81±0.1 g/cm3 (Predicted)

Boiling Point: 569.9±60.0 °C at 760 mmHg

InChIKey: IZFJAICCKKWWNM-JXOAFFINSA-N

CanonicalSMILES: COC1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O

IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methoxypyrimidin-2-one

InChI: InChI=1S/C10H15N3O6/c1-18-4-2-13(10(17)12-8(4)11)9-7(16)6(15)5(3-14)19-9/h2,5-7,9,14-16H,3H2,1H3,(H2,11,12,17)/t5-,6-,7-,9-/m1/s1

Synonyms: 5-Methoxy cytidine; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methoxypyrimidin-2(1H)-one; NSC 339193; 5-OMe-Cr

N6-(4-Methyoxybenzoyl)adenosine

Description: N6-(4-Methoxybenzoyl)adenosine, a chemical compound, finds its essential use in investigating adenosine receptors in the domain of biomedicine, towards seeking cures for a diverse range of diseases. Its therapeutic potential is particularly noteworthy and extends to neurological conditions like Parkinson's disease and Alzheimer's disease, not to forget the noteworthy anti-inflammatory effects it has on cardiovascular diseases. The effective binding to adenosine receptors makes it fertile ground for exploring wider possibilities in the study of diseases.

CAT: BRP-01761

CAS: 56883-05-7

Molecular Formula: C18H19N5O6

Molecular Weight: 401.37

Purity: ≥97% by HPLC

Appearance: White to pale yellow solid

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Storage: Store at -20°C

Density: 1.67±0.1 g/cm3 (Predicted)

InChIKey: YDVLBCYELIMFHS-XWXWGSFUSA-N

CanonicalSMILES: COC1=CC=C(C=C1)C(=O)NC2=C3C(=NC=N2)N(C=N3)C4C(C(C(O4)CO)O)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]-4-methoxybenzamide

InChI: InChI=1S/C18H19N5O6/c1-28-10-4-2-9(3-5-10)17(27)22-15-12-16(20-7-19-15)23(8-21-12)18-14(26)13(25)11(6-24)29-18/h2-5,7-8,11,13-14,18,24-26H,6H2,1H3,(H,19,20,22,27)/t11-,13-,14-,18-/m1/s1

Synonyms: N6-Anisoyladenosine; Adenosine, N-(4-methoxybenzoyl)-; N-(p-Anisoyl)adenosine; N-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)-4-methoxybenzamide; N-(4-Methoxybenzoyl)adenosine; 6-N-p-Anisoyladenosine

N2-Phenoxyacetylguanosine

Description: N2-Phenoxyacetylguanosine, a renowned biomedical compound, garners attention due to its exceptional anti-viral qualities. Refined scientific research highlights its profound role as a potent inhibitor, effectively impeding the replication processes of select viruses through specific targeting of their viral enzymes. This exceptional product exhibits remarkable efficacy in combating viral infections triggered by distinct RNA viruses. Intriguingly, its mechanism of action disrupts viral RNA synthesis, presenting immense prospects for the development of avant-garde antiviral therapies.

CAT: BRP-01762

CAS: 119824-66-7

Molecular Formula: C18H19N5O7

Molecular Weight: 417.37

Purity: ≥95%

Appearance: White to Yellow Crystalline Powder

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Storage: Store at 2-8°C

Density: 1.76±0.10 g/cm3

Melting Point: 159-160 °C

InChIKey: FOOYAXZEBFXEJD-IWCJZZDYSA-N

CanonicalSMILES: C1=CC=C(C=C1)OCC(=O)NC2=NC3=C(C(=O)N2)N=CN3C4C(C(C(O4)CO)O)O

IUPAC Name: N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-phenoxyacetamide

InChI: InChI=1S/C18H19N5O7/c24-6-10-13(26)14(27)17(30-10)23-8-19-12-15(23)21-18(22-16(12)28)20-11(25)7-29-9-4-2-1-3-5-9/h1-5,8,10,13-14,17,24,26-27H,6-7H2,(H2,20,21,22,25,28)/t10-,13-,14-,17-/m1/s1

Synonyms: Gua(pac); 2-N-phenoxyacetylguanosine; N-[9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl]-2-phenoxy-acetamide; N-(Phenoxyacetyl)guanosine; ribo Guanosine (n-PAC); N2-PAC-rG; N-(2-Phenoxyacetyl)guanosine

5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine

Description: 5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine, a compound widely employed in the realm of biomedicine, encapsulates vast prospects for therapeutic interventions in an array of ailments, encompassing viral infections and select malignancies. Possessing an idiosyncratic molecular configuration, this enigmatic substance has attained an eminent stance within drug exploration and advancement, particularly pertaining to nucleoside chemistry.

CAT: BRP-01763

CAS: 251647-51-5

Molecular Formula: C33H36N2O9

Molecular Weight: 604.65

Purity: ≥98% by HPLC

Appearance: White to Faint Yellow Powder

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Storage: Store at 2-8°C

Density: 1.34±0.1 g/cm3(Predicted)

InChIKey: YVYKKLNOXPCFGC-PMFUCWTESA-N

CanonicalSMILES: COCCOC1C(C(OC1N2C=CC(=O)NC2=O)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O

IUPAC Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]pyrimidine-2,4-dione

InChI: InChI=1S/C33H36N2O9/c1-39-19-20-42-30-29(37)27(44-31(30)35-18-17-28(36)34-32(35)38)21-43-33(22-7-5-4-6-8-22,23-9-13-25(40-2)14-10-23)24-11-15-26(41-3)16-12-24/h4-18,27,29-31,37H,19-21H2,1-3H3,(H,34,36,38)/t27-,29-,30-,31-/m1/s1

Synonyms: 5'-O-DMT-2'-O-(2-Methoxyethyl)-Uridine; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(2-methoxyethyl)uridine; 1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)uridine; 5'-O-DMT-2'-O-MOE-Ur

N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-cytidine

Description: N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-cytidine, an influential nucleoside analogue with potent antiviral properties, is extensively employed across the biomedical sector. Its remarkable efficacy extends to a diverse range of DNA and RNA viruses, encompassing herpesvirus, papillomavirus, and retroviruses. Notably, this compound showcases promising outcomes in impeding viral replication, thereby presenting itself as a promising therapeutic avenue for combating viral infections and associated ailments.

CAT: BRP-01764

CAS: 251647-49-1

Molecular Formula: C40H41N3O9

Molecular Weight: 707.77

Purity: ≥95%

Appearance: White to Off-white Powder or Crystals

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Storage: Store at -20°C

Density: 1.26±0.1 g/cm3 (Predicted)

InChIKey: PRAZQDMVAGLVKR-XHOUGWTJSA-N

CanonicalSMILES: COCCOC1C(C(OC1N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O

IUPAC Name: N-[1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

InChI: InChI=1S/C40H41N3O9/c1-47-24-25-50-36-35(44)33(52-38(36)43-23-22-34(42-39(43)46)41-37(45)27-10-6-4-7-11-27)26-51-40(28-12-8-5-9-13-28,29-14-18-31(48-2)19-15-29)30-16-20-32(49-3)21-17-30/h4-23,33,35-36,38,44H,24-26H2,1-3H3,(H,41,42,45,46)/t33-,35-,36-,38-/m1/s1

Synonyms: 5'-O-DMT-N4-BZ-2'-O-(2-Methoxyethyl)-Cytidine; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)cytidine; N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-(2-methoxyethyl)cytidine; 5'-O-DMT-2'-O-MOE-C(Bz)

Arabinofuranosyl-hypoxanthine (ara-HX)

Description: Arabinofuranosyl-hypoxanthine is a prodrug of Vidarabine for improving the oral bioavailability, which is an antiviral drug. It is an antimetabolic nucleoside that inhibits Streptococcus pyogenes and other bacteria, as well as zirconium oxide, pulmonary vasodilation, squamous cell carcinoma, and rate constant.

CAT: BRP-01769

CAS: 7013-16-3

Molecular Formula: C10H12N4O5

Molecular Weight: 268.22

Purity: ≥98%

Appearance: White or off-white solid

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Storage: Store at 2-8 °C

Density: 2.08±0.1 g/cm3

Melting Point: 259-260 °C

Boiling Point: 797.9±60.0 °C at 760 mmHg

Application: Antiviral Agents

InChIKey: UGQMRVRMYYASKQ-UHTZMRCNSA-N

Solubility: Soluble in DMSO (Slightly), Water (Slightly)

CanonicalSMILES: C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)CO)O)O

IUPAC Name: 9-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one

InChI: InChI=1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6-,7+,10-/m1/s1

Synonyms: Arabinofuranosyl-hypoxanthine; Arabino inosine; 9-β-D-Arabinofuranosyl-1,9-dihydro-6H-purin-6-one; Hypoxanthine, 9-β-D-arabinofuranosyl-; 9-β-D-Arabinofuranosylhypoxanthine; Ara-H; Arabinosylhypoxanthine; Arainosine; Hypoxanthine arabinoside; NSC 405122; 9-(β-D-Arabinofuranosyl)-hypoxanthine

2-Amino-9-(2-O-methyl-β-D-ribofuranosyl)purine

Description: 2-Amino-9-(2-O-methyl-β-D-ribofuranosyl)purine is a renowned pharmaceutical compound, boasting its exceptional potency as an antiviral agent. With a distinctive focus on combating the likes of hepatitis C and diverse DNA viruses, this product manifests remarkable efficacy in hindering viral replication.

CAT: BRP-01770

CAS: 274259-35-7

Molecular Formula: C11H15N5O4

Molecular Weight: 281.27

Purity: ≥97%

Appearance: White or off-white solid

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Storage: Store at 2-8 °C

Density: 1.84±0.1 g/cm3

Boiling Point: 654.1±65.0 °C at 760 mmHg

InChIKey: UQKXGJSZRSHLBF-FDDDBJFASA-N

CanonicalSMILES: COC1C(C(OC1N2C=NC3=CN=C(N=C32)N)CO)O

IUPAC Name: (2R,3R,4R,5R)-5-(2-aminopurin-9-yl)-2-(hydroxymethyl)-4-methoxyoxolan-3-ol

InChI: InChI=1S/C11H15N5O4/c1-19-8-7(18)6(3-17)20-10(8)16-4-14-5-2-13-11(12)15-9(5)16/h2,4,6-8,10,17-18H,3H2,1H3,(H2,12,13,15)/t6-,7-,8-,10-/m1/s1

Synonyms: 2-Amino-9-(2'-O-methyl-beta-D-ribofuranosyl)-9H-purine; 9-(2-O-Methyl-β-D-ribofuranosyl)-9H-purin-2-amine; 2-Amino-9-(2-o-methyl-β-d-ribofuranosyl)purine

2-Thiocytidine

Description: 2-Thiocytidine, a nucleoside analogue, is a potent anti-cancer agent that shows promise in treating several types of cancer, including leukemia, lymphoma, and solid tumors. Through interference with the DNA synthesis process, it effectively halts cancer cell growth, while also demonstrating antiviral activity towards HIV and hepatitis B. From these qualities, it is clear that 2-Thiocytidine holds tremendous potential as a therapeutic agent for the treatment of cancer and viral infections.

CAT: BRP-01771

CAS: 13239-97-9

Molecular Formula: C9H13N3O4S

Molecular Weight: 259.28

Purity: ≥95%

Appearance: Off-white to Dark Brown Solid

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Storage: Store at -20°C under inert atmosphere

Density: 1.85±0.1 g/cm3(Predicted)

Melting Point: 208-209 °C

Boiling Point: 540.5±60.0 °C at 760 mmHg

Symbol: s²C

InChIKey: RHFUOMFWUGWKKO-XVFCMESISA-N

Solubility: Soluble in Methanol (Slightly), Water (Slightly)

CanonicalSMILES: C1=CN(C(=S)N=C1N)C2C(C(C(O2)CO)O)O

IUPAC Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2-thione

InChI: InChI=1S/C9H13N3O4S/c10-5-1-2-12(9(17)11-5)8-7(15)6(14)4(3-13)16-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,17)/t4-,6-,7-,8-/m1/s1

Synonyms: Cytidine, 2-thio-; 4-amino-1-beta-D-ribofuranosylpyrimidine-2(1H)-thione; 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2(1H)-thione; 2(1H)-Pyrimidinethione, 4-amino-1-β-D-ribofuranosyl-

2'-O-Methyl-2-thiouridine

Description: 2'-O-Methyl-2-thiouridine is a valuable compound widely used in biomedicine. It acts as an RNA modification tool, incorporating into RNA molecules during synthesis. This powerful molecule exhibits antiviral activity against various viral infections, making it a potential therapeutic option for treating RNA virus-associated diseases. Its unique properties and versatility make it an essential tool for studying RNA biology and developing antiviral therapies.

CAT: BRP-01772

CAS: 113886-72-9

Molecular Formula: C10H14N2O5S

Molecular Weight: 274.29

Purity: ≥95%

Appearance: Off-white to Brown Powder

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Storage: Store at 2-8 °C

Density: 1.55±0.1 g/cm3 (Predicted)

Symbol: s²Um

InChIKey: WARUUAMZJXEUEA-ZOQUXTDFSA-N

CanonicalSMILES: COC1C(C(OC1N2C=CC(=O)NC2=S)CO)O

IUPAC Name: 1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-2-sulfanylidenepyrimidin-4-one

InChI: InChI=1S/C10H14N2O5S/c1-16-8-7(15)5(4-13)17-9(8)12-3-2-6(14)11-10(12)18/h2-3,5,7-9,13,15H,4H2,1H3,(H,11,14,18)/t5-,7-,8-,9-/m1/s1

Synonyms: 2-thio-2'-O-methyluridine; Uridine, 2'-O-methyl-2-thio-; 1-(2-O-Methyl-β-D-ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone; 4(1H)-Pyrimidinone, 2,3-dihydro-1-(2-O-methyl-β-D-ribofuranosyl)-2-thioxo-; 1-((2R,3R,4R,5R)-4-Hydroxy-5-hydroxymethyl-3-methoxy-tetrahydro-furan-2-yl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

N4-Aminocytidine

Description: N4-Aminocytidine is a cytidine analog where an amino group is attached to the nitrogen at the 4th position of the cytosine base. This modification can be used in biochemical and molecular biology research to study nucleic acid interactions, enzymatic activity, and as a potential antiviral or anticancer agent. The presence of the additional amino group can influence base pairing and the overall stability of nucleic acids, providing a useful tool for exploring nucleic acid structure and function. It inhibits the growth of Escherichia coli and Salmonella typhimurium in vitro. It binds to the bacterial ribosome and inhibits protein synthesis, which results in cell death.

CAT: BRP-01773

CAS: 57294-74-3

Molecular Formula: C9H14N4O5

Molecular Weight: 258.23

Purity: ≥98%

Appearance: White or off-white solid

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Storage: Store at 2-8 °C

Density: 1.93±0.1 g/cm3

InChIKey: RSSRMDMJEZIUJX-XVFCMESISA-N

Solubility: Soluble in DMSO (Slightly), Water (Slightly)

CanonicalSMILES: C1=CN(C(=O)N=C1NN)C2C(C(C(O2)CO)O)O

IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydrazinylpyrimidin-2-one

InChI: InChI=1S/C9H14N4O5/c10-12-5-1-2-13(9(17)11-5)8-7(16)6(15)4(3-14)18-8/h1-2,4,6-8,14-16H,3,10H2,(H,11,12,17)/t4-,6-,7-,8-/m1/s1

Synonyms: Uridine, 4-hydrazone; Uridine 4-hydrazone; Cytidine, N-amino-; EIDD 1910; N-Aminocytidine; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydrazinylpyrimidin-2(1H)-one

L-Uridine

L-Inosine

1,N6-Ethenoadenosine

N4-Ethenocytidine

2,2'-Anhydrocytidine

2,2'-Cyclocytidine hydrochloride

3-Methyluridine

N6-Phenoxyacetyladenosine

N4-Benzoyl-5-methylcytidine

1-(6-Amino-9-β-D-ribofuranosyl-9H-purin-2-yl)-1H-pyrazole-4-carboxylic Acid Ethyl Ester

5-Methoxycytidine

N6-(4-Methyoxybenzoyl)adenosine

N2-Phenoxyacetylguanosine

5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine

N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)-cytidine

Arabinofuranosyl-hypoxanthine (ara-HX)

2-Amino-9-(2-O-methyl-β-D-ribofuranosyl)purine

2-Thiocytidine

2'-O-Methyl-2-thiouridine

N4-Aminocytidine

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